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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 109 records · Page 6
All sourcesNASA NTRSDOE OSTI
DOE OSTI2023

Using CRISPR/Cas13a technologies to detect miRNA [DOE SULI Internship Report]

Micro ribonucleic acids (miRNA) give our immune systems the ability to recognize viruses and other pathogens by their complementary single-stranded RNA (ssRNA) produced in the reproduction of the pathogen in our cells. When miRNA of a specific sequence is detected in a cell sample, it can be assumed that the immune system is activated and attempting to track down the infection. This pathway can be utilized to diagnose infection from a pathogen before the individual even develops symptoms, aiding in early disease detection and proper treatment. One of the ways that we can detect miRNA is through an assay of clustered regularly interspaced short palindromic repeats or “CRISPR” and the bacterial protein Cas13a. This report details discoveries made while attempting to optimize this assay for miRNA detection. After looking at several different factors within the assay, it was determined that some factors, such as reporter type and metallic ion concentration, are more impactful on the overall assay sensitivity than other factors, such as the overall concentration of Cas13a, CRISPR RNA (crRNA), or ssRNA reporter. It was also discovered that different sequences with different lengths require renewed optimization efforts, as each target has a unique binding affinity determined by the sequence length and composition. This information is crucial in the development of point of care molecular detection devices as they become sensitive enough to identify pathogens before they spread.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2024

Integrating PCTRAN with AI-Driven Host-Intrusion Detection and Secured Container Systems for Advanced Malware Analysis (Summer Internship Report)

This study presents a solution for enhancing the security of the Personal Computer Transient Analyzer (PCTRAN) PC-based Nuclear Power Plant Simulator by integrating the software with an artificial intelligence (AI)-driven host-intrusion detection system (HIDS), in addition to a secured container system, for malware analysis. PCTRAN is a Windows XP-based software package that has the ability to simulate a variety of accident and transient conditions for nuclear power plants (NPPs). It offers a high-resolution replica of the Nuclear Steam Supply System (NSSS) and displays the status of important parameters allowing for operator interaction. By including AI-driven HIDS for the NSSS, the framework can identify security threats in real-time, ensuring the integrity of the nuclear simulation environment. Additionally, the secured container system offers the ability to isolate and analyze malware, preventing potential threats from affecting core systems. The integration process involves extensive testing and validation in order to ensure accuracy, reliability, and compliance with security policies. This framework sets a new precedent for secure simulation and training in NPP operations, and offers insight for future advancements in cybersecurity.

21 SPECIFIC NUCLEAR REACTORS AND ASSOCIATED PLANTS↗
DOE OSTI2024

QuarkNet Center Summer Internship for High School Students – FY2023

The purpose of this CRADA is to provide the contractual vehicle for Fermilab to receive funds from the College of DuPage in support of high school student research working with the Fermilab/University of Chicago QuarkNet Center, beginning with the effective date of this CRADA and continuing through 2023. Local QuarkNet Centers provide professional development programs to high school teachers and high energy physics research opportunities to high school teachers and students who participate in the local programs. The Office of Education and Public Engagement at Fermi National Accelerator Laboratory (Fermilab) administers a local QuarkNet Center program on behalf of both Fermilab and the University of Chicago.

99 GENERAL AND MISCELLANEOUS↗
DOE OSTI2024

Once-Through Steam Generator Model Analysis Using Python and Advanced Optimization Tools (Summer Internship Report)

This study focuses on the parametric analysis of design parameters for a once-through steam generator (OTSG) model, using python and advanced optimization tools to facilitate applications such as the flowing autoclave steam generator (FASG) test cases. Building on previous research involving another OTSG with a different design, this project aims to enhance our understanding of how steam generators (SGs) behave and how their outputs are influenced by changes in design. The reason for this design change is to allow for more precise modeling and optimization of SG performance, to provide a comparative analysis between the two designs, and to set up the model for integration with the FASG test case. The OTSG python-model is a mathematical representation (including fluid flow and heat transfer equations/models/correlations) of a steam-generating unit in a pressurized water reactor-type small modular reactor system. Design studies involve changing the model’s input design parameters to observe the resulting effects on the output of the system. By using advanced optimization tools, such as the Risk Analysis Virtual Environment (RAVEN) developed at Idaho National Laboratory, detailed design parametric studies and model optimization were performed. Six input parameters—pressure, temperature, and mass flow rate for the inlet of the primary-side (hot fluid) and secondary-side (cold fluid), respectively, of the SG—were randomly perturbed via RAVEN’s Monte Carlo Sampler module, using uniform distributions (i.e., ±1%, ±5% and ±10% relative changes) for 600 samples. The analysis provides valuable insights into SG optimization and can be used for sensor placement optimization to effectively monitor and obtain experimental data in other tests.

20 FOSSIL-FUELED POWER PLANTS↗
DOE OSTI2024

Implementing a Laser Stabilization System for Trapping Ca+ Ions: an Internship Reflection

At Lawrence Livermore National Laboratory, I contributed to a project developing 3D printed micro ion traps for quantum computing. I designed, implemented, and assessed a laser stabilization system that locked lasers to the frequencies required for calibrating our High Finesse WS8-10 wavelength meter and for laser cooling and trapping of Ca+ ions. I also programmed a Python interface for hardware communication, data collection, and statistical analysis. Additionally, I optimized and aligned laser beam paths, and I implemented a closed digital feedback loop using Proportional, Integral, and Derivative (PID) control parameters. I analyzed both the long-term and short-term behavior of our locked lasers and adjusted PID parameters to enhance performance. Furthermore, I used COMSOL to simulate the capacitance of a linear Paul trap design and predict our trap’s performance. The procedures I developed for the interface, analysis, and simulations will continue to support the ion trapping experiment after my appointment. I strengthened my skills in data analysis, Python coding, and optical alignment for laser systems. My confidence as a researcher grew, particularly in communicating my research. This experience taught me the importance of careful planning and consideration in research and solidified my desire to continue exploring novel quantum technology as an undergraduate

42 ENGINEERING↗
DOE OSTI2024

QuarkNet Center Summer Internship for High School Students – FY2024

The purpose of this CRADA is to provide the contractual vehicle for Fermilab to receive funds from the College of DuPage in support of high school student research working with the Fermilab/University of Chicago QuarkNet Center, beginning with the effective date of this CRADA and continuing through 2024. Local QuarkNet Centers provide professional development programs to high school teachers and high energy physics research opportunities to high school teachers and students who participate in the local programs. The Office of Education and Public Engagement at Fermi National Accelerator Laboratory (Fermilab) administers a local QuarkNet Center program on behalf of both Fermilab and the University of Chicago.

99 GENERAL AND MISCELLANEOUS↗
DOE OSTI2025

Roxana Paramo Ramirez: MSIIP 2025-2026 Internship [Poster]

At Sandia National Laboratories, there is a high level of importance placed on identifying and developing solutions to the nation’s current and future security problems. One of these problem would be hardware electronics validation and verification.

42 ENGINEERING↗
DOE OSTI2025

Summer Internship Report: ARA2 Benchmarking

Over the past decade, the RISC-V Instruction Set Architecture (ISA) has emerged as a significant player in both academic and industrial processor design due to its open-source nature, modular extension system, and versatility across domains ranging from microcontrollers to high-performance computing (HPC). One of its most important recent advancements is the RISC-V Vector Extension (RVV), which enables explicit data-level parallelism through vector registers and vectorized instructions. Unlike traditional SIMD (Single Instruction, Multiple Data) architectures that fix vector lengths at design time, RVV uses the concept of VLEN (vector register length) as a hardware-independent parameter and allows software to adapt dynamically to the available vector width. This flexible approach ensures portability across implementations while enabling scalable performance. The ARA2 core is a parameterizable RISC-V vector processor developed at the Integrated Systems Lab at ETH Zürich and the University of Bologna. Designed as a tightly-coupled accelerator to a scalar RISC-V core, ARA2 implements the RVV 1.0 specification and offers tunable architectural parameters such as the number of vector lanes, VLEN, and cache sizes.

97 MATHEMATICS AND COMPUTING↗
DOE OSTI2025

Trigger-System Development for the HGCAL Cassette Testing (Final Report, Summer Internship 2023)

The Large Hadron Collider (LHC) will be upgraded to increase the instantaneous luminosity, which will result in an increase in the number of collisions from the 15 pile-up events of the first run of phase 1 to the 150-200 pile-up events of phase 2. Increasing the number of collisions means increasing the amount of radiation that the experiments will absorb. To meet these challenging conditions, the CMS calorimeters need to be upgraded. The new version of the hadronic HGCAL (High Granularity CALorimeters) in the endcaps will be assembled and tested in Fermilab’s laboratory. This report describes the new trigger system for testing the HGCAL’s cassettes.

42 ENGINEERING↗
DOE OSTI2023

Study of NuMI Dirt Monte Carlo Events in the ICARUS T600 Detector (Fermilab Internship Final Report)

The moving of the Icarus detector from Laboratori Nazionali del Gran Sasso to Fermilab in order to pursue the physics goals of the Short-Baseline Neutrino (SBN) program has introduced the necessity of a more careful study of backgrounds. In this work some developments of the validation of the Monte Carlo backgrounds for the Icarus run 1 data taking are presented, focusing on the study of the so called “Dirt” events from the NuMI beamline. In particular the analysis hints at a possible underestimation of the muon background. Hopefully this issue will be solved at a later stage of the analysis with the inclusion of components that were not considered in the present work.

43 PARTICLE ACCELERATORS↗
DOE OSTI2025

Advancing Neutrino Simulation Modeling with MARLEY: Insights from the NNSA-MSIIP Internship

Core-collapse supernovae are intense sources of tens-of-MeV neutrinos. However, there is no experimental data to validate the current event generator MARLEY (Model of Argon Reaction Low Energy Yields) that can model supernova neutrinos. To validate the model, I developed a new muon capture feature within the MARLEY simulation framework by coding key functions in C++, Python, and ROOT. I generated and analyzed one million simulated muon capture events and comparing the results to experimental data. To improve the model, I worked on optimizing the model’s parameters to improve its precision using statistical methods.

Wong, Baker [Fermilab]↗
DOE OSTI2026

Fermilab 2025 Summer Internship: Repairing Pre-Amplifiers with Mu2e Electronics Installation Team

The author spent nine weeks over summer 2025 working on the tracker electronics installation team for the Mu2e experiment. One of her main responsibilities was repairing high voltage (HV) and calibration (Cal) pre-amplifiers (pre-amps). During installation, the fragile wires connecting the two sockets to the pre-amp board must be bent, often leading to breakage. During production, the sockets and wires were initially soldered to the board at UC Berkely, then the whole pre-amp was coated in parylene before transport to Fermilab. The interns were able to expedite the repairs, and thus whole installation process, by using an alternative method on-site with epoxy. Another task they were responsible for, not included in the original project specifications, was attaching copper clips to specific vias on the Cals to reduce noise. The talk will give listeners insight into the daily problem-solving required by the novel technologies in the Mu2e project. The author would like to acknowledge her fellow Monmouth College undergraduate interns, Lizzie Durfee and Gianna Maughan, advisor and PI of the DOE RENEW Grant Dr. Christopher G. Fasano, and the Mu2e team lead by co-spokesperson Dr. Bob Bernstein and tracker L2 manager Dr. Brendan Kiburg.

de Zwart, Bronte [Monmouth Coll.]↗
DOE OSTI2026

Fermilab 2025 Summer Internship Skills Learned from Working with Mu2e Tracker Team

As part of a DOE RENEW Grant, the undergraduate authors interned at Fermilab. They spent nine weeks over summer 2025 working on the tracker team for the Mu2e experiment. They gained practical experience in a multitude of new skills including electronics installation, testing, and repairs. Their work particularly increased productivity by helping repair the high voltage and calibration pre-amplifiers, over 20,000 of which are needed in the tracker. These components are very fragile and often break during the installation process. The experience also taught them several soft skills such as the importance of thoughtful data storage, record- keeping, and problem-solving skills. They learned the demands of a large, international collaboration and how to work in a team. The authors would like to acknowledge their advisor and PI of the grant, Dr. Christopher G. Fasano, and the Mu2e team lead by co- spokesperson Dr. Bob Bernstein and tracker L2 manager Dr. Brendan Kiburg.

de Zwart, Brontë↗
DOE OSTI2026

IMPACT 2025-2026 Internship Poster

At Sandia National Laboratories, I developed a C++ program that converts printed circuit boards(PCB) and integrated circuits(IC) design files to be compatible for computed tomography (CT) simulations through Monte Carlo methods.

97 MATHEMATICS AND COMPUTING↗
DOE OSTI2026

Internship overview

Explore the source record for details and available documents.

42 ENGINEERING↗
DOE OSTI2026

Fuel Performance Modeling Internship Final Presentation

This study examines the performance of U-Zr and U-Pd-Zr annular metallic fuel rodlets and details the current status of modeling efforts regarding U-Pu-Zr solid metallic fuel rodlets which were experimentally evaluated as part of the Advanced Fuels Campaign (AFC). The AFC mission is to develop novel fuel technologies and facilitate the implementation of those technologies by industry partners. A key objective is to improve steady-state and transient performance over current fuel types. The experiments of interest in this study included metallic fuel rodlets within HT-9 cladding which were placed in SS-316 capsules and inserted in the Advanced Test Reactor (ATR). Certain mechanical and thermal conditions cannot be directly evaluated through experiments and fuel performance modeling is used to shed light on this evolution over time. In this study, BISON Multiphysics simulations are leveraged to investigate the state of the fuel system throughout and after the experimental conditions.

11 - NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗
NASA NTRS1980

Traditional and nontraditional internships in government

Traditional and nontraditional methods for training technical writers-editors within the federal government are discussed. It is concluded that cooperative education that combines work experience with classroom instruction provides an excellent method for locating and training competent and reliable young professionals.

Stohrer, Freda F.↗
NASA NTRS1994

Engineering Internship Program Report

Towards the end of the summer, I prepared for a presentation to the chief of the Flight Crew Support Division to obtain funding for Phase 1 of the project. I presented information on the tracking systems, David Ray presented on the POGO and PABF and the integration of the virtual reality systems, and Mike Van Chau talked about other hardware issues such as head-mounted display, 3-D sound, gloves, graphics platforms, and other peripherals. The funding was approved, and work was to begin at the end of August in evaluating a couple of the tracking systems, to integrate the graphics platform and video equipment with the POGO, and to build a larger gantry for the POGO. This tour I learned how to effectively gather information and present them in a convincible form to gain funding. I explored a entirely new area of technology, that being virtual reality from the most general form down to finer details in its tracking systems. The experiences over the summer have added a lot of detail to work at the Johnson Space Center, life within NASA, and to the many possibilities for becoming involved with the space program.

Bosch, Brian Y.↗