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At least 109 records · Page 6

AgMIP-Wheat Multi-Model Simulations on Climate Change Impact and Adaptation for Global Wheat

The climate change impact and adaptation simulations from the Agricultural Model Intercomparison and Improvement Project (AgMIP) for wheat provide a unique dataset of multi-model ensemble simulations for 60 representative global locations covering all global wheat mega environments. The multi-model ensemble reported here has been thoroughly benchmarked against a large number of experimental data, including different locations, growing season temperatures, atmospheric CO2 concentration, heat stress scenarios, and their interactions. In this paper, we describe the main characteristics of this global simulation dataset. Detailed cultivar, crop management, and soil datasets were compiled for all locations to drive 32 wheat growth models. The dataset consists of 30-year simulated data including 25 output variables for nine climate scenarios, including Baseline (1980-2010) with 360 or 550 ppm CO2, Baseline +2oC or +4oC with 360 or 550 ppm CO2, a mid-century climate change scenario (RCP8.5, 571 ppm CO2), and 1.5°C (423 ppm CO2) and 2.0oC (487 ppm CO2) warming above the pre-industrial period (HAPPI). This global simulation dataset can be used as a benchmark from a well-tested multi-model ensemble in future analyses of global wheat. Also, resource use efficiency (e.g., for radiation, water, and nitrogen use) and uncertainty analyses under different climate scenarios can be explored at different scales. The DOI for the dataset is 10.5281/zenodo.4027033 (AgMIP-Wheat, 2020), and all the data are available on the data repository of Zenodo (http://doi.org/10.5281/zenodo.4027033). Two scientific publications have been published based on some of these data here.

Agricultural Model Intercomparison and Improvement↗

RadLab: Graphical and Programming Interfaces for Interrogation of Space Telemetry Data

Sensors on multiple spacecraft in and beyond low Earth orbit continuously monitor and collect space radiation data and transmit it back to Earth. These data are of vast importance to space biology research, as ionizing radiation affects living organisms—astronauts and non-human experiment subjects alike—placing them at higher risk of carcinogenesis, degenerative diseases, and radiation sickness. Therefore, knowledge of the biological effects of space radiation is essential for planning future crewed missions beyond low Earth orbit. The RadLab project, initiated by GeneLab and ALSDA (the Open Science Data Repository; OSDR) and sponsored by the NASA Human Research Program, is a new effort aimed at connecting dosimetry data from radiation detectors located on the International Space Station (ISS), as well as other spacecraft. To date, access to these data has been fragmented across space agencies and databases; to address this issue, we have developed an application programming interface (API) and an associated graphical user interface (GUI) designed to provide a single point of access to the data. As of now, OSDR has focused on the detectors located on the ISS, with the long-term goal to establish a self-sustained portal receiving continuous updates through APIs connecting to multiple radiation databases of varying scope, as well as individual investigator contributions. The RadLab API implements a request syntax enabling users to query data by craft, sensor type, timespan, etc, allowing for arbitrary combinations of original source data, thus providing programmatic access for use in computational pipelines, while the GUI facilitates data visualization and exploration, making these data FAIR (Findable, Accessible, Interoperable, and Reusable), complementing the biological data contained in OSDR, and providing the space science community with a valuable resource for scientific analyses.

radiation↗

Continental Spatio-Temporal Data Analysis with Linear Spectral Mixture Model Using FOSS

This work demonstrates the development and implementation of a Fully Constrained Least Squares (FCLS) unmixing model developed in C++ programming language with OpenCV package and boost C++ libraries in the NASA Earth Exchange (NEX). Visualization of the results is supported by GRASS GIS and statistical analysis is carried in R in a Linux system environment. FCLS was first tested on computer simulated data with Gaussian noise of various signal-to-noise ratio, and Landsat data of an agricultural scenario and an urban environment using a set of global end members of substrate (soils, sediments, rocks, and non-photosynthetic vegetation), vegetation that includes green photosynthetic plants and dark objects which encompasses absorptive substrate materials, clear water, deep shadows, etc. For the agricultural scenario, a spectrally diverse collection of 11 scenes of Level 1 terrain corrected, cloud free Landsat-5 TM data of Fresno, California, USA were unmixed and the results were validated with the corresponding ground data. To study an urbanized landscape, a clear sky Landsat-5 TM data were unmixed and validated with coincident World View-2 abundance maps (of 2 m spatial resolution) for an area of San Francisco, California, USA. The results were evaluated using descriptive statistics, correlation coefficient, RMSE, probability of success, boxplot and bivariate distribution function. Finally, FCLS was used for sub-pixel land cover analysis of the monthly WELD (Wen-enabled Landsat data) repository from 2008 to 2011 of North America. The abundance maps in conjunction with DMSP-OLS nighttime lights data were used to extract the urban land cover features and analyze their spatial-temporal growth.

Landsat Satellites↗

RadLab Platform: Investigating Space Radiation

The RadLab Project, initiated by the Open Science Data Repository (OSDR) for Space Biology at NASA Ames Research Center (osdr.nasa.gov), aims to be an ongoing compilation of radiation data relevant to human space flight. Sponsored by the NASA Human Research Program, RadLab serves as the latest database in this domain. RadLab is intended to serve the needs of both the space radiation detector and space radiation biology communities. The RadLab architecture is being designed to accommodate data both from low Earth orbit (LEO) and beyond low Earth orbit (BLEO). Our long-term vision entails the establishment of a sustainable database receiving continuous updates through APIs connecting to other databases, as well as individual investigator contributions via a RadLab submission portal, modeled on the OSDR (https://osdr.nasa.gov/bio/submission-sso-login.html). In addition to serving as a resource for space biologists and space radiation physicists, such a database would facilitate the deployment of AI algorithms to study the impact of location in space and within spacecraft on the ambient space radiation field. The ultimate goal is to develop predictive dosimetry algorithms for future BLEO missions.

Sylvain V Costes↗

RadLab: A Comprehensive Database and Graphical and Programming Interfaces for Biologically Relevant Space Radiation Data

RadLab, a new component of the NASA Open Science Data Repository (OSDR), comprises a database of radiation measurements relevant to space biology, and visual and programmatic interfaces for interrogation and retrieval of these data. The attributes of data available through RadLab include spacecraft, types of radiation sensing instruments, locations within the spacecraft (e.g. modules of the ISS), associated celestial bodies, trajectories, and spacecraft coordinates. The application programming interface (API) implements a request syntax for retrieval of timestamped data filtered by various combinations of such attributes; the graphical user interface (GUI) extends this functionality with visualizations, such as spacecraft schematics, time series plots, geospatial visualizations, and provides easy means to iteratively refine search parameters, inspect the data on the fly, and download target subsets of these data. The release of RadLab currently available to the public contains datasets provided by US and international collaborators and focuses on data recorded on the ISS. Investigators from multiple countries, including the US, Canada, Germany, Bulgaria, Hungary, Italy, Japan, Russia and the Czech Republic, have committed to provide data from their instruments in and beyond low Earth orbit; RadLab will also soon expand to include past (e.g. Shuttle and Mir) and future (e.g. Artemis) data. RadLab will provide a comprehensive, dynamic compendium of space radiation data, enabling the scientific community to perform analyses of data from multiple detectors and to determine the radiation environment of research missions and experiments, both via programmatic retrieval of these data and through the graphical analysis toolkit. The RadLab Working Group has been formed to foster collaborations among data contributors and users, to identify data sources, to put in place standards for data harmonization, and to guide the development of the platform, with the goal to establish the use of RadLab in space radiation research and to advance our understanding of the space radiation environment in human habitats.

radiation↗

RadLab: A Comprehensive Database and Graphical and Programming Interfaces for Biologically Relevant Space Radiation Data

RadLab, a new component of the NASA Open Science Data Repository (OSDR), comprises a database of radiation measurements relevant to space biology, and visual and programmatic interfaces for interrogation and retrieval of these data. The attributes of data available through RadLab include spacecraft, types of radiation sensing instruments, locations within the spacecraft (e.g. modules of the ISS), associated celestial bodies, trajectories, and spacecraft coordinates. The application programming interface (API) implements a request syntax for retrieval of timestamped data filtered by various combinations of such attributes; the graphical user interface (GUI) extends this functionality with visualizations, such as spacecraft schematics, time series plots, geospatial visualizations, and provides easy means to iteratively refine search parameters, inspect the data on the fly, and download target subsets. The release of RadLab currently available to the public contains datasets provided by US and international collaborators and focuses on data recorded on the ISS. Investigators from multiple countries, including the US, Canada, Germany, Bulgaria, Hungary, Italy, Japan, Russia and the Czech Republic, have committed to provide data from their instruments in and beyond low Earth orbit; RadLab will also soon expand to include past (e.g. Shuttle and Mir) and future (e.g. Artemis) data. RadLab will provide a comprehensive, dynamic compendium of space radiation data, enabling the scientific community to perform analyses of data from multiple detectors and to determine the radiation environment of research missions and experiments. The RadLab Working Group has been formed to foster collaborations among data contributors and users, to identify data sources, to put in place standards for data harmonization, and to guide the development of the platform, with the goal to establish the use of RadLab in space radiation research and to advance our understanding of the space radiation environment in human habitats.

database↗

Cloud-Based Orchestration of a Model-Based Power and Data Analysis Toolchain

The proposed Europa Mission concept contains many engineering and scientific instruments that consume varying amounts of power and produce varying amounts of data throughout the mission. System-level power and data usage must be well understood and analyzed to verify design requirements. Numerous cross-disciplinary tools and analysis models are used to simulate the system-level spacecraft power and data behavior. This paper addresses the problem of orchestrating a consistent set of models, tools, and data in a unified analysis toolchain when ownership is distributed among numerous domain experts. An analysis and simulation environment was developed as a way to manage the complexity of the power and data analysis toolchain and to reduce the simulation turnaround time. A system model data repository is used as the trusted store of high-level inputs and results while other remote servers are used for archival of larger data sets and for analysis tool execution. Simulation data passes through numerous domain-specific analysis tools and end-to-end simulation execution is enabled through a web-based tool. The use of a cloud-based service facilitates coordination among distributed developers and enables scalable computation and storage needs, and ensures a consistent execution environment. Configuration management is emphasized to maintain traceability between current and historical simulation runs and their corresponding versions of models, tools and data.

Post, Ethan↗

High School Citizen Scientists Use AI/ML to Predict Intra-Ocular Pressure From Gene Expression Data for Spaceflown Mice

Artificial Intelligence (AI) and Machine Learning (ML) have increasingly become pivotal in biological and biomedical research, largely due to the culture of open data sharing and its associated benefits. The methodologies inherent in AI/ML are particularly adept at identifying and forecasting biological phenotypes from the vast amounts of data generated by next-generation sequencing technologies. These techniques offer substantial promise for advancing research in space biosciences and for the development of automated systems for monitoring space health. Nevertheless, there are crucial aspects to consider when training, validating, and testing machine learning models in both biological research and clinical contexts. It is essential that Open Science principles, including data sharing and the availability of open-source code, are complemented by high-quality, publicly accessible training resources. These resources should focus on best practices and include modules based on real-world scientific cases and data to ensure that future AI/ML practitioners gain practical experience with genuine problems. Addressing this knowledge gap, we have designed, developed, and delivered both interactive and self-paced training programs for citizen scientists worldwide, enabling them to utilize AI/ML for space biology research. This initiative was made possible through generous funding from a Transformation to Open Science Training grant. The interactive training sessions, conducted this summer, utilized AI/ML techniques to analyze data from the Open Science Data Repository, specifically targeting the effects of spaceflight on ocular structure and function. The dataset OSD-583, from the Rodent Research 9 mission, provides experimental data detailing the ocular responses of mice subjected to a 35-day spaceflight, compared with ground control counterparts. Using OSD-583 as observational data, our summer training participants applied AI/ML methods to predict intraocular pressure from RNA-seq data and identify the genes most predictive of the observed responses. Further analysis through pathway enrichment and gene set enrichment revealed that these genes are involved in molecular and cellular processes contributing to retinal degeneration.

James Casaletto↗

RadLab: A Comprehensive Database and Graphical and Programming Interfaces for Space Radiation Data

RadLab, a component of the NASA Open Science Data Repository (OSDR), is a database of radiation measurements from multiple instruments and spacecraft that provides visual and programmatic interfaces for interrogation and retrieval of these data. The attributes of data available through RadLab include spacecraft, types of radiation sensing instruments, locations within the spacecraft (e.g. ISS modules), associated celestial bodies, trajectories, and spacecraft coordinates; the primary type of data is the absorbed dose rate, as well as flux and dose equivalent rate where available. The application programming interface (API) implements a request syntax for retrieval of timestamped data filtered by various combinations of such attributes; the graphical user interface (GUI) extends this functionality with visualizations (time series plots, comparison plots, geospatial visualizations) which provide easy means to assess data availability, iteratively refine search parameters, interactively inspect the data, and export target data subsets. Datasets are continuously being added to the RadLab database as part of the rolling release process. Investigators from multiple countries, including the US, Canada, Germany, Bulgaria, Hungary, Italy, Japan, Russia and the Czech Republic, have committed to provide data from their instruments in and beyond low Earth orbit. The current release contains datasets provided by US and international collaborators and includes readings from multiple modules of the ISS, the BioSentinel CubeSat, Chang’e 4, the Lunar Reconnaissance Orbiter, the ExoMars Orbiter, and the Curiosity rover. Datasets are associated with respective RadLab knowledgebase articles which include instrument descriptions and provide bibliographical references. RadLab aims to provide a comprehensive, dynamic compendium of space radiation data, enabling the scientific community to perform analyses of data from multiple detectors and to determine the radiation environment of research missions and experiments. Some of its applications include inference of absorbed radiation dose for NASA GeneLab payloads, and training predictive models as part of the 2024 FDL-X challenge. The platform is actively expanding and seeking additional data, with plans to also cover past (e.g. Shuttle, Mir) and future (e.g. Artemis) missions. The RadLab Working Group has been created to aid in this process as well as to foster collaborations among data contributors and users, to develop standards for data harmonization, and to guide the development of the platform, with the goal to establish the use of RadLab in space radiation research and to advance our understanding of the radiation environment in outer space.

Kirill Grigorev↗

RadLab: A Comprehensive Database and Graphical and Programming Interfaces for Space Radiation Data

RadLab, a component of the NASA Open Science Data Repository (OSDR), is a database of radiation measurements from multiple instruments and spacecraft that provides visual and programmatic interfaces for interrogation and retrieval of these data. The attributes of data available through RadLab include spacecraft, types of radiation sensing instruments, locations within the spacecraft (e.g. ISS modules), associated celestial bodies, trajectories, and spacecraft coordinates; the primary type of data is the absorbed dose rate, as well as flux and dose equivalent rate where available. The application programming interface (API) implements a request syntax for retrieval of timestamped data filtered by various combinations of such attributes; the graphical user interface (GUI) extends this functionality with visualizations (time series plots, comparison plots, geospatial visualizations) which provide easy means to assess data availability, iteratively refine search parameters, interactively inspect the data, and export target data subsets. Datasets are continuously being added to the RadLab database as part of the rolling release process. Investigators from multiple countries, including the US, Canada, Germany, Bulgaria, Hungary, Italy, Japan, Russia and the Czech Republic, have committed to provide data from their instruments in and beyond low Earth orbit. The current release contains datasets provided by US and international collaborators and includes readings from multiple modules of the ISS, the BioSentinel CubeSat, Chang’e 4, the Lunar Reconnaissance Orbiter, the ExoMars Orbiter, and the Curiosity rover. Datasets are associated with respective RadLab knowledgebase articles which include instrument descriptions and provide bibliographical references. RadLab aims to provide a comprehensive, dynamic compendium of space radiation data, enabling the scientific community to perform analyses of data from multiple detectors and to determine the radiation environment of research missions and experiments. Some of its applications include inference of absorbed radiation dose for NASA GeneLab payloads, and training predictive models as part of the 2024 FDL-X challenge. The platform is actively expanding and seeking additional data, with plans to also cover past (e.g. Shuttle, Mir) and future (e.g. Artemis) missions. The RadLab Working Group has been created to aid in this process as well as to foster collaborations among data contributors and users, to develop standards for data harmonization, and to guide the development of the platform, with the goal to establish the use of RadLab in space radiation research and to advance our understanding of the radiation environment in outer space.

Kirill Grigorev↗

GL4U: Using Space Biology Omics Data to Provide Bioinformatics Training for Students and Educators

NASA’s GeneLab project provides researchers open access to space-relevant multi-omics data via the Open Science Data Repository (OSDR) that can be mined to understand the effects of spaceflight on biological systems. To maximize the number of scientists who understand and utilize GeneLab data and data processing pipelines, GeneLab created GeneLab for Colleges and Universities (GL4U). GL4U provides space biology-relevant training in bioinformatics to the next generation of scientists through direct (training students) and indirect (training educators) approaches. The GL4U pilot programs were conducted in June 2021 (direct training) and 2022 (indirect training). During the pilots, students and educators at Historically Black Colleges and Universities (HBCUs) and Minority Serving Institutions (MSIs) participated in a week-long (direct training) or two-week-long (indirect training) bootcamp consisting of space biology-specific lectures and hands-on instruction using Jupyter Notebooks to analyze space biology RNA sequencing data from OSDR. During the educator pilot, participants received materials, training, and the necessary compute resources to enable them to run the bootcamp at their home institutions, thereby extending the reach of this initiative. In July 2023, GeneLab is partnering with JPL to expand GL4U to include amplicon sequencing (Amp-Seq) analysis training. During the GL4U Amp-Seq bootcamp, student and educator participants will receive training on how to analyze and interpret Amp-Seq data using the NASA GeneLab data processing pipeline. All bootcamp material, including instructions for requesting compute resources, will be made publicly available on GitHub for educators to teach the GL4U content in subsequent semesters. GL4U provides undergraduate students from underrepresented groups the opportunity to learn about NASA and Space Biology, and to enhance their career prospects by gaining hands-on experience analyzing omics data, a skillset that is highly applicable and marketable in the life sciences. We present results from pre- and post-training surveys completed by all participants of the Amp-Seq bootcamp.

Amanda M Saravia-Butler↗

Development of Solar Flare and Energetic Particle Prediction Portal (SEP 3 )

Solar activity is a primary factor determining the state of the Earth’s space environment, geomagnetic and ionospheric disturbances, and radiation hazards. In the current state of knowledge, machine learning (ML) methods provide essential tools for processing data, investigating relationships among various physical properties and characteristics, uncovering hidden connections, and predicting hazardous solar events. The primary difficulty in developing and applying modern machine-learning tools in heliophysics is that the essential data are scattered among over a hundred data repositories developed by instrument teams of space missions and ground-based observatories. In addition, statistical and ML methods require long time series of homogeneous measurements. To facilitate ML-ready data preparation and access, we have developed an interactive database of solar flares integrating the most essential datasets (https://solarflare.njit.edu/). The database performs an initial data processing and is automatically updated. In addition, we are developing the Solar Energetic Particle Prediction Portal (SEP3, https://sun.njit.edu/SEP3), which hosts web applications that allow users to retrieve the database records. The Portal has a search page for browsing the events from the most widely used catalogs and a dedicated space to share the most recent achievements of the team. The interactive widget can display soft X-ray and proton flux time series from GOES satellites and the flare records. The data portal has been used to evaluate the forecasts of solar proton events and investigate machine-learning approaches to SEP prediction.

SMD↗

Greenland and Canadian Arctic Ice Temperature Profiles Database

Here, we present a compilation of 95 ice temperature profiles from 85 boreholes from the Greenland ice sheet and peripheral ice caps, as well as local ice caps in the Canadian Arctic. Profiles from only 31 boreholes (36 %) were previously available in open-access data repositories. The remaining 54 borehole profiles (64 %) are being made digitally available here for the first time. These newly available profiles, which are associated with pre-2010 boreholes, have been submitted by community members or digitized from published graphics and/or data tables. All 95 profiles are now made available in both absolute (meters) and normalized (0 to 1 ice thickness) depth scales and are accompanied by extensive metadata. These metadata include a transparent description of data provenance. The ice temperature profiles span 70 years, with the earliest profile being from 1950 at Camp VI, West Greenland. To highlight the value of this database in evaluating ice flow simulations, we compare the ice temperature profiles from the Greenland ice sheet with an ice flow simulation by the Parallel Ice Sheet Model (PISM). We find a cold bias in modeled near-surface ice temperatures within the ablation area, a warm bias in modeled basal ice temperatures at inland cold-bedded sites, and an apparent underestimation of deformational heating in high-strain settings. These biases provide process level insight on simulated ice temperatures.

Greenland↗

Governing Data Findability, Accessibility, Interoperability and Reusability (FAIR) Compliance

The most recent data strategy documents at both the federal and NASA levels stipulate that systems should strive for the data they manage to be Findable, Accessible, Interoperable, and Reusable (FAIR). The NASA Life Sciences Portal (NLSP) has already begun leading efforts in this area for HRP, initiating efforts to comply with the FAIR principles. The broad interpretation of the FAIR principles has led to a plethora of tools that use a splay of metrics specifically but variably developed to judge how compliant data and systems are with the principles. A recent review [3] identified and studied 1,180 metrics across 20 publicly available tools for checking FAIR compliance of data and systems. Because of their very recent development, many organizations and data systems managers and developers have not yet had adequate time or resources to understand these FAIR compliance tools and metrics, their variations in design, accuracy or ease of application to their specific data sets and systems. Thus, it would be best for larger organizations like NASA to approach formulating a strategy for governance of FAIR compliance that can be flexibly applied and is adaptable to an evolving awareness knowledge of FAIR compliance methods and tools. In September 2024, the NASA Science Mission Directorate(SMD) organized a workshop on NASA science data repositories, including the topics of implementing FAIR and governing FAIR compliance across SMD. The initial part of these FAIR discussions focused on developing consensus around required science metadata fields. This is challenging given the diverse nature of NASA’s scientific data portfolio, the variety of metadata models and vocabularies used, and variable level of resources available to curate these data. Later discussion focused on three possible approaches to governing FAIR compliance: distributed, in which various programs, projects or systems define their own methods for assessing FAIR compliance, reporting results up appropriate management lines; centralized, in which higher-level organization(s) specify compliance tools or methods for the various data systems; and multi-level, in which a group comprised of individuals with expertise from multiple levels with organizations is formed to provide guidance and/or specifications for governing FAIR compliance. We report on the recommendations this session yielded, and how these might be shaped specifically to help implement and govern the compliance with FAIR of Human Research Program data and systems.

governance↗

New Developments in NASA's Rodent Research Hardware for Conducting Long Duration Biomedical and Basic Research in Space

Animal models, particularly rodents, are the foundation of pre-clinical research to understand human diseases and evaluate new therapeutics, and play a key role in advancing biomedical discoveries both on Earth and in space. The National Research Councils Decadal survey emphasized the importance of expanding NASA's life sciences research to perform long duration, rodent experiments on the International Space Station (ISS) to study effects of the space environment on the musculoskeletal and neurological systems of mice as model organisms of human health and disease, particularly in areas of muscle atrophy, bone loss, and fracture healing. To accomplish this objective, flight hardware, operations, and science capabilities were developed at NASA Ames Research Center (ARC) to enhance science return for both commercial (CASIS) and government-sponsored rodent research. The Rodent Research Project at NASA ARC has pioneered a new research capability on the International Space Station and has progressed toward translating research to the ISS utilizing commercial rockets, collaborating with academia and science industry, while training crewmembers to assist in performing research on orbit. The Rodent Research Habitat provides a living environment for animals on ISS according to standard animal welfare requirements, and daily health checks can be performed using the habitats camera system. Results from these studies contribute to the science community via both the primary investigation and banked samples that are shared in publicly available data repository such as GeneLab. Following each flight, through the Biospecimen Sharing Program (BSP), numerous tissues and thousands of samples will be harvested, and distributed from the Space Life and Physical Sciences (SLPS) to Principal Investigators (PIs) through the Ames Life Science Data Archive (ALSDA). Every completed mission sets a foundation to build and design greater complexity into future research and answer questions about common human diseases. Together, the hardware improvements (enrichment, telemetry sensors, cameras), new capabilities (live animal return), and experience that the Rodent Research team has gained working with principal investigator teams and ISS crew to conduct complex experiments on orbit are expanding capabilities for long duration rodent research on the ISS to achieve both basic science and biomedical research objectives.

Shirazi, Yasaman↗

NASA’s Data Preservation Strategies for Ensuring Ongoing Use and Access: Leveraging the Capabilities at the NASA DAACs

As NASA prepares for the follow on to EOS through the deployment of many new space and airborne-based assets envisioned under the ESO initiative, the need for ensuring user access to the very large and diverse archive of past missions remains a critical endeavor for current and future research. The ESDIS team has been working for many years on developing strategies and implementations that will make the linkage between the data held in our archives and the emerging missions possible. The focus on how best to preserve these past data has proven to be a collaborative effort, and one that may well benefit from the adoption of innovative technical tools that enable organizational efficiencies. This poster reveals both aspects of NASA’s EOS data repository strategy by discussing the collaborative community efforts of development of ISO 19165-2 – an international standard supported by a team from many countries around the world, the use by EOSDIS DAACs of a Preservation Content Specification, and ongoing work with mission teams to ensure mission data and all associated information are preserved and available for current and future use.

Francis Lindsay↗

Nasa Genelab - Knowledge Graph Fabric Enables Deep Biomedical Analysis of Multi-Omics Datasets

The limited number of astronauts and human samples from long-duration space missions pose significant challenges for studying the health risks associated with spaceflight and developing new treatments. As a result, much of our understanding of the biological impact of space travel relies on samples from model organisms. NASA GeneLab, integrated into Open Science Data Repository (OSDR) is a centralized multi-omics resource containing almost 1000 datasets from over 500 space-related studies from human and model organism samples. Previous studies have demonstrated that human phenotypes and physiological changes caused by spaceflight can be identified by connecting gene expression data from model organisms flown in space to a biomedical knowledge graph (SPOKE). In this work, we present a data fabric connecting OSDR datasets to SPOKE that empowers biomedical analyses through the GeneLab visualization portal. This collaboration is funded by NSF’s Proto-OKN program.

data fabric↗