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At least 109 records · Page 6

Accurate universal parameterization of absorption cross sections

We present a simple universal parameterization of total reaction cross sections for any system of colliding nuclei valid for the entire energy range from a few A MeV to a few A GeV. The universal picture presented here treats the proton-nucleus collision as a special case of the nucleus-nucleus collision, where the projectile has charge and mass number one. The parameters are associated with the physics of the collision system. In general terms Coulomb interaction modifies cross sections at lower energies and the effects of Pauli blocking are important at higher energies. The agreement between the calculated and experimental data is better than all earlier published results.

NASA Discipline Radiation Health

Chemical Process Safety at TRISO-Based, Metal-Based, and Salt-Based Fuel Fabrication Facilities: Technical Assessment and Guidance Assessment

As part of efforts to prepare for potential and ongoing safety reviews for licensing of advanced non-light-water reactor fuel cycles, the U.S. Nuclear Regulatory Commission (NRC) tasked Pacific Northwest National Laboratory to prepare an assessment on the state of knowledge of potential chemical processes at fuel cycle facilities supporting the front end of these fuel cycles, and to assess the associated regulatory guidance. This report provides a technical assessment of chemical process safety considerations to support NRC licensing reviews of fabrication processes for tri-structural isotropic (TRISO) based, metallic-based, and salt-based fuels. The assessments involved collecting publicly available information on the fuel fabrication processes to (i) identify the operational process steps, characteristics and chemicals involved, (ii) identify the physical safety considerations and health safety considerations during licensing reviews of the various process steps, and (iii) collect information to support assessments of severity of accidents and potential mitigative measures to be implemented. The assessment provides a foundational basis on chemical process safety considerations for advanced fuel fabrication activities, although it is recognized that licensing reviews may necessitate design-specific considerations. The specific conditions under which chemical hazards emerge will require process-specific considerations, highlighting the importance of process-informed interpretation. The assessment also determined that exposure guidelines and limits to assess the consequences of acute exposures are limited for some chemicals, although alternative limits and supplementary information from databases or safety data sheets provide sufficient information to evaluate consequences of acute exposures. In addition, it was identified that metallic and salt fuel fabrication processes may involve beryllium, which is an exposure hazard. The regulatory framework for the licensing of advanced fuel cycle facilities, per 10 CFR Part 70 Domestic Licensing of Special Nuclear Material, is deemed robust and flexible to address the chemical safety considerations in this report. A review was conducted on various regulatory guidance and technical basis documents. This included reviewing NUREG-1520, Revision 2, Standard Review Plan for Fuel Cycle Facilities License Applications – Final Report and the process descriptions in Appendix A of NUREG/CR-6410, Nuclear Fuel Cycle Facility Accident Analysis Handbook, to address advanced fuel types. As new fuels will involve process-specific chemical uses, process-specific considerations are provided in this report. Additionally, it is noted that the U.S. Department of Energy protective action criteria database includes Temporary Emergency Exposure Limits (TEELs) for process-specific chemicals. This report provides technical information to support chemical safety assessments of new advanced fuel cycle facilities and identifies technical and safety information to support licensing reviews. No regulatory barriers were identified for the licensing of advanced fuel cycle facilities.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS

Latent Herpes Viruses Reactivation in Astronauts

Space flight has many adverse effects on human physiology. Changes in multiple systems, including the cardiovascular, musculoskeletal, neurovestibular, endocrine, and immune systems have occurred (12, 32, 38, 39). Alterations in drug pharmacokinetics and pharmacodynamics (12), nutritional needs (31), renal stone formation (40), and microbial flora (2) have also been reported. Evidence suggests that the magnitude of some changes may increase with time in space. A variety of changes in immunity have been reported during both short (.16 days) and long (>30 days) space missions. However, it is difficult to determine the medical significance of these immunological changes in astronauts. Astronauts are in excellent health and in superb physical condition. Illnesses in astronauts during space flight are not common, are generally mild, and rarely affect mission objectives. In an attempt to clarify this issue, we identified the latent herpes viruses as medically important indicators of the effects of space flight on immunity. This chapter demonstrates that space flight leads to asymptomatic reactivation of latent herpes viruses, and proposes that this results from marked changes in neuroendocrine function and immunity caused by the inherent stressfullness of human space flight. Astronauts experience uniquely stressful environments during space flight. Potential stressors include confinement in an unfamiliar, crowded environment, isolation, separation from family, anxiety, fear, sleep deprivation, psychosocial issues, physical exertion, noise, variable acceleration forces, increased radiation, and others. Many of these are intermittent and variable in duration and intensity, but variable gravity forces (including transitions from launch acceleration to microgravity and from microgravity to planetary gravity) and variable radiation levels are part of each mission and contribute to a stressful environment that cannot be duplicated on Earth. Radiation outside the Earth's magnetosphere is particularly worrisome because it includes ionizing radiation from cosmic galactic radiation. Increased stress levels appear even before flight, presumably from the rigors of preflight training and the anticipation of the mission (12, 32, 38, 39). Space flight causes significant changes in human immune function (32), but the means by which these changes come about have been difficult to discern. Consistent indicators of stress associated with space flight include increased production of stress hormones, and changes in cells of the immune system. These changes include elevated white blood cell (WBC) and neutrophil counts at landing (15, 16, 35, 37). Activation of generalized stress responses before, during, and after space flight probably affects the function of the immune system. Space flight has been shown to decrease many aspects of immune function, including natural killer (NK) cell activity, interferon production, the blastogenic response of leukocytes to mitogens, cell-mediated immunity, neutrophil function and monocyte function (5, 16, 18, 21, 35-37).

Mehta, Satish K.

Human Integration Design Processes (HIDP)

The purpose of the Human Integration Design Processes (HIDP) document is to provide human-systems integration design processes, including methodologies and best practices that NASA has used to meet human systems and human rating requirements for developing crewed spacecraft. HIDP content is framed around human-centered design methodologies and processes in support of human-system integration requirements and human rating. NASA-STD-3001, Space Flight Human-System Standard, is a two-volume set of National Aeronautics and Space Administration (NASA) Agency-level standards established by the Office of the Chief Health and Medical Officer, directed at minimizing health and performance risks for flight crews in human space flight programs. Volume 1 of NASA-STD-3001, Crew Health, sets standards for fitness for duty, space flight permissible exposure limits, permissible outcome limits, levels of medical care, medical diagnosis, intervention, treatment and care, and countermeasures. Volume 2 of NASASTD- 3001, Human Factors, Habitability, and Environmental Health, focuses on human physical and cognitive capabilities and limitations and defines standards for spacecraft (including orbiters, habitats, and suits), internal environments, facilities, payloads, and related equipment, hardware, and software with which the crew interfaces during space operations. The NASA Procedural Requirements (NPR) 8705.2B, Human-Rating Requirements for Space Systems, specifies the Agency's human-rating processes, procedures, and requirements. The HIDP was written to share NASA's knowledge of processes directed toward achieving human certification of a spacecraft through implementation of human-systems integration requirements. Although the HIDP speaks directly to implementation of NASA-STD-3001 and NPR 8705.2B requirements, the human-centered design, evaluation, and design processes described in this document can be applied to any set of human-systems requirements and are independent of reference missions. The HIDP is a reference document that is intended to be used during the development of crewed space systems and operations to guide human-systems development process activities.

Boyer, Jennifer

Coordination of International Risk-Reduction Investigations by the Multilateral Human Research Panel for Exploration

Effective use of the unique capabilities of the International Space Station (ISS) for risk reduction on future deep space missions involves preliminary work in analog environments to identify and evaluate the most promising techniques, interventions and treatments. This entails a consolidated multinational approach to biomedical research both on ISS and in ground analogs. The Multilateral Human Research Panel for Exploration (MHRPE) was chartered by the five ISS partners to recommend the best combination of partner investigations on ISS for risk reduction in the relatively short time available for ISS utilization. MHRPE will also make recommendations to funding agencies for appropriate preparatory analog work. In 2011, NASA's Human Research Program (HRP) and the Institute of Biomedical Problems (IBMP) of the Russian Academy of Science, acting for MHRPE, developed a joint US-Russian biomedical program for the 2015 one-year ISS mission (1YM) of American and Russian crewmembers. This was to evaluate the possibilities for multilateral research on ISS. An overlapping list of 16 HRP, 9 IBMP, 3 Japanese, 3 European and 1 Canadian investigations were selected to address risk-reduction goals in 7 categories: Functional Performance, Behavioral Health, Visual Impairment, Metabolism, Physical Capacity, Microbial and Human Factors. MHRPE intends to build on this bilateral foundation to recommend more fully-integrated multilateral investigations on future ISS missions commencing after the 1YM. MHRPE has also endorsed an on-going program of coordinated research on 6-month, one-year and 6-week missions ISS expeditions that is now under consideration by ISS managers. Preparatory work for these missions will require coordinated and collaborative campaigns especially in the psychological and psychosocial areas using analog isolation facilities in Houston, Köln and Moscow, and possibly elsewhere. The multilateral Human Analogs research working group (HANA) is the focal point of those planning discussions, with MHRPE coordinating between the national programs and then supporting implementation on ISS. Experience gained during preparations for the 1YM has identified improvements in both American and Russian processes to enable well-integrated investigations on all subsequent ISS expeditions. Among those is that the greatest efficiency is to be gained with investigations that are fully integrated from their conception, with co-principal investigators, a consolidated proposal and integrated plans for crewmember time and other flight-related resources. Analog investigations preceding future ISS expeditions will employ these lessons in efficiency to evaluate the techniques and tools to be validated aboard ISS. In this way, the resources and capabilities of ISS can be applied most efficiently to solving the problems facing astronauts of all nations in missions deep into the solar system.

Charles, John B.

Software and System Health Management with R2U2

R2U2 (Realizable, Responsive, Unobtrusive Unit) is a hardware-supported tool and framework for the real-time system and software health management of cyber-physical systems. R2U2 continuously monitors properties about safety, performance, and security of the vehicle and can perform diagnostic reasoning. Efficient observers for past-time and future-time Metric Temporal Logic, reasoners for Bayesian Networks, and model-based prognostics algorithms are major components of R2U2. Their combination makes it possible to design powerful models for system runtime monitoring, diagnostics, software health management, prognostics, and security monitoring. The R2U2 monitoring engine is designed for minimal runtime overhead and is available as Simulink block or as a software component for integration into the flight software stack, and enables R2U2 to monitor complex cyber-physical systems without any instrumentation of the flight software. In this presentation, we give an overview of R2U2 architecture and reasoning algorithms, present its features, and give a life demo of the tool.

Schumann, Johann

Cytogenetic effects of space radiation in lymphocytes of MIR-18 crews

For assessing health risk, the measurement of physical dose received during a space mission, as well as the LETs, energies and charges of particles is important. It is also important to obtain quantitative information regarding the effectiveness of space radiation in causing damage to critical biological targets, e.g., chromosomes, since at present the estimated uncertainty of biological effects of space radiation is more than a factor of two. Such large uncertainty makes accurate health risk assessment very difficult. For this very reason, a study on cytogenetic effects of space radiation in human lymphocytes was proposed and done for MIR-18 mission. This study used FISH technique to score chromosomal translocations and C-banding method to determine dicentrics. Growth kinetics of cells and SCE were examined to ensure that chromosomal aberrations were scored in first mitosis and were induced not by chemical mutagens. Our results showed that chromosomal aberration frequency of post-flight samples was significantly higher than that of pre-flight ones and that SCE frequency was similar between pre- and post-flight samples. Based on a dose-response curve of preflight samples exposed to gamma rays, the absorbed dose received by crews during the mission was estimated to be about 14.5 cSv. Because the absorbed dose measured by physical dosimeters is 4.16 cGy for the entire mission, the RBE is about 3.5.

Mir Project

Intelligent Engine Systems Work Element 1.3: Sub System Health Management

The objectives of this program were to develop health monitoring systems and physics-based fault detection models for engine sub-systems including the start, lubrication, and fuel. These models will ultimately be used to provide more effective sub-system fault identification and isolation to reduce engine maintenance costs and engine down-time. Additionally, the bearing sub-system health is addressed in this program through identification of sensing requirements, a review of available technologies and a demonstration of a demonstration of a conceptual monitoring system for a differential roller bearing. This report is divided into four sections; one for each of the subtasks. The start system subtask is documented in section 2.0, the oil system is covered in section 3.0, bearing in section 4.0, and the fuel system is presented in section 5.0.

Ashby, Malcolm

A Cryogenic Fluid System Simulation in Support of Integrated Systems Health Management

Simulations serve as important tools throughout the design and operation of engineering systems. In the context of sys-tems health management, simulations serve many uses. For one, the underlying physical models can be used by model-based health management tools to develop diagnostic and prognostic models. These simulations should incorporate both nominal and faulty behavior with the ability to inject various faults into the system. Such simulations can there-fore be used for operator training, for both nominal and faulty situations, as well as for developing and prototyping health management algorithms. In this paper, we describe a methodology for building such simulations. We discuss the design decisions and tools used to build a simulation of a cryogenic fluid test bed, and how it serves as a core technology for systems health management development and maturation.

cryogenics

Runtime Monitoring with R2U2 for Aircraft Systems with Neural Networks

R2U2 (Realizable, Responsive, Unobtrusive Unit) is a hardware-supported tool and framework for real-time system monitoring and software health management of cyber-physical systems. During system operation, R2U2 continuously monitors properties about safety, performance, and security of the vehicle and its vital components and can perform diagnostic reasoning. Efficient observers for past-time and future-time Metric Temporal Logic, fast reasoners for Bayesian Networks, and model-based prognostics algorithms are key components of R2U2 and designed for minimal computational footprint. R2U2 has been implemented in software supporting ROS, NASA's cFS/cFE, and Simulink and as an FPGA configuration. The synergistic combination of monitors and observers in R2U2 makes it possible to design powerful models for system runtime monitoring, diagnostics, software health management, prognostics, and security monitoring. In this presentation, I will give a detailed overview of the R2U2 architecture and its features and will discuss the application of R2U2 for safety-monitoring of a neural-network based autonomous centerline tracking system (ACT) for autonomous aircraft.

Runtime Monitoring

Power modeling of degraded PV systems: Case studies using a dynamically updated physical model (PV-Pro)

Power modeling, widely applied for health monitoring and power prediction, is crucial for the efficiency and reliability of Photovoltaic (PV) systems. The most common approach for power modeling uses a physical equivalent circuit model, with the core challenge being the estimation of model parameters. Traditional parameter estimation either relies on datasheet information, which does not reflect the system's current health status, especially for degraded PV systems, or requires additional I-V characterization, which is generally unavailable for large-scale PV systems. Thus, we build upon our previously developed tool, PV-Pro (originally proposed for degradation analysis), to enhance its application for power modeling of degraded PV systems. PV-Pro extracts model parameters from production data without requiring I-V characterization. This dynamic model, periodically updated, can closely capture the actual degradation status, enabling precise power modeling. PV-Pro is compared with popular power modeling techniques, including persistence, nominal physical, and various machine learning models. The results indicate that PV-Pro achieves outstanding power modeling performance, with an average nMAE of 1.4 % across four field-degraded PV systems, reducing error by 17.6 % compared to the best alternative technique. Furthermore, PV-Pro demonstrates robustness across different seasons and severities of degradation. The tool is available as a Python package at https://github.com/DuraMAT/pvpro.

14 SOLAR ENERGY

Moving NASA Remote Sensing Data to the GIS Environment for Health Studies

There has been an increasing demand by the health community for improved data on many different environmental factors relevant to the links between the environment and disease occurrence and transmission. These data are important for GIS-based monitoring, risk mapping, and surveillance of epidemiological parameters on a large number of different spatial, temporal, and spectral resolutions. Accordingly, NASA is developing new approaches to data collection and distribution in order to improve access to multiple sources of data streams to increase spatial and temporal coverage. Methods are being developed to incorporate different, scalable capabilities to handle multiple data sources by adding, deleting and replacing components as required as well as associated tools for their management. An approach has been to search for innovative solutions focused on the creation, use and manipulation of data stored in many different archives. These include data transformation and combination as well as data and information tools that can assist the public health and science community to use existing and anticipated products in new and flexible ways. This presentation will provide an inventory of geophysical parameters derived from satellite remote sensing sensors that are useful for GIS-based public health studies. The presentation will also discuss the physical and scientific limitations of access to and use of these data for health applications such as resolution and format differences, lack of software interoperability, data access problems. Finally, there will be a summary of the recent steps the NASA program has taken to bring NASA-generated satellite products to a wider range of users in the GIS community.

Vicente, Gilberto A.

Image-Driven Hybrid Structural Analysis Based on Continuum Point Cloud Method with Boundary Capturing Technique

Conventional approaches for the structural health monitoring of infrastructures often rely on physical sensors or targets attached to structural members, which require considerable preparation, maintenance, and operational effort, including continuous on-site adjustments. This paper presents an image-driven hybrid structural analysis technique that combines digital image processing (DIP) and regression analysis with a continuum point cloud method (CPCM) built on a particle-based strong formulation. Polynomial regressions capture the boundary shape change due to the structural loading and precisely identify the edge and corner coordinates of the deformed structure. The captured edge profiles are transformed into essential boundary conditions. This allows the construction of a strongly formulated boundary value problem (BVP), classified as the Dirichlet problem. Capturing boundary conditions from the digital image is novel, although a similar approach was applied to the point cloud data. It was shown that the CPCM is more efficient in this hybrid simulation framework than the weak-form-based numerical schemes. Unlike the finite element method (FEM), it can avoid aligning boundary nodes with regression points. A three-point bending test of a rubber beam was simulated to validate the developed technique. The simulation results were benchmarked against numerical results by ANSYS and various relevant numerical schemes. The technique can effectively solve the Dirichlet-type BVP, yielding accurate deformation, stress, and strain values across the entire problem domain when employing a linear strain model and increasing the number of CPCM nodes. In addition, comparative analysis with conventional displacement tracking techniques verifies the developed technique’s robustness. The proposed technique effectively circumvents the inherent limitations of traditional monitoring methods resulting from the reliance on physical gauges or target markers so that a robust and non-contact solution for remote structural health monitoring in real-scale infrastructures can be provided, even in unfavorable experimental environments.

Chemistry

DESSY: Making a real-time expert system robust and useful

As the complexity and expected life-span of modern space systems continue to increase, the need for real-time data monitoring and failure analysis becomes more critical to their successful operation. The DEcision Support SYstem (DESSY) is a joint effort by the Intelligent Systems Branch/ER2 and the Remote Manipulator System (RMS) Section/DF44 to develop an expert system for the monitoring of the Payload Deployment and Retrieval System (PDRS). DESSY users, the RMS flight controllers, are provided with user interface enhancements and automated monitoring of system state (physical orientation) and status (operational health). Currently, a DESSY prototype for the Manipulator Positioning Mechanism (MPM) and Manipulator Retention Latches (MRL) of the PDRS has been developed and successfully demonstrated during the STS-49 and STS-46 missions. Expert systems for monitoring real-time operations must not only accurately represent domain knowledge, but also address the challenges of using unfiltered real-time data as input. This paper describes the methods and design strategies developed to overcome problems with real-time data in the NASA Mission Control Center. Types of data problems addressed are as follows: (1) loss of data; (2) erratic data; and (3) data lags and irregularities during state transition. Methods used to handle data problems include rule disabling for ignoring data when data quality is uncertain, context-sensitive bounded pattern recognition for minimizing incorrect conclusions based on bad data, and graceful recovery through system correction when reliable data returns. This combination of methods with an object-based modular DESSY design assures a robust program capable of lengthy periods of uninterrupted use in operations.

Land, Sherry A.

US-USSR telemedicine consultation spacebridge to Armenia and Ufa

The Final Report on the U.S.-U.S.S.R. Telemedicine Consultation Spacebride to Armenia and Ufa is presented. The goal of this activity was to provide expert medical consultation to the Armenian medical personnel in the areas of plastic and reconstructive surgery, physical and psychological rehabilitation, public health, and epidemiology following the devastating earthquake in Dec. 1988. The U.S. and U.S.S.R. implementation teams developed new standards for medical information transmittal as well as protocols and schedules on how to conduct medical consultations. The consultations were provided to the Republic Diagnostic Center in Yerevan, U.S.S.R. by four U.S. medical centers: University of Utah/LDS Hospital, University of Texas, Maryland Institute for Emergency Medical Service Systems, and Uniformed Services University of the Health Sciences.

Source record

Bio-Optical and Remote Sensing Observations in Chesapeake Bay

The high temporal and spatial resolution of satellite ocean color observations will prove invaluable for monitoring the health of coastal ecosystems where physical and biological variability demands sampling scales beyond that possible by ship. However, ocean color remote sensing of Case 2 waters is a challenging undertaking due to the optical complexity of the water. The focus of this SIMBIOS support has been to provide in situ optical measurements from Chesapeake Bay (CB) and adjacent mid-Atlantic bight (MAB) waters for use in algorithm development and validation efforts to improve the satellite retrieval of chlorophyll (chl a) in Case 2 waters. CB provides a valuable site for validation of data from ocean color sensors for a number of reasons. First, the physical dimensions of the Bay (> 6,500 km2) make retrievals from satellites with a spatial resolution of approx. 1 km (i.e., SeaWiFS) or less (i.e., MODIS) reasonable for most of the ecosystem. Second, CB is highly influenced by freshwater flow from major rivers, making it a classic Case 2 water body with significant concentrations of chlorophyll, particulates and chromophoric dissolved organic matter (CDOM) that highly impact the shape of reflectance spectra.

Harding, Lawrence W., Jr.

Evaluation and Validation of Case 2 Algorithms in Chesapeake Bay

The high temporal and spatial resolution of satellite ocean color observations will prove invaluable for monitoring the health of coastal ecosystems where physical and biological variability demands sampling scales beyond that possible by ship. However, ocean color remote sensing of Case 2 waters is a challenging undertaking due to the optical complexity of the water. The focus of this SIMBIOS support has been to provide in situ optical measurements form Chesapeake Bay (CB) and adjacent mid-Atlantic bight (MAB) waters for use in algorithm development and validation efforts to improve the satellite retrieval of chlorophyll (chl a) in Case 2 waters. CB provides a valuable site for validation of data from ocean color sensors for a number of reasons. First, the physical dimensions of the Bay (greater than 6,500 square kilometers) make retrievals from satellites with a spatial resolution of approximately 1 kilometer (i.e., SeaWiFS) or less (i.e., MODIS) reasonable for most of the ecosystem. Second, CB is highly influenced by freshwater flow from major rivers, making it a classic Case 2 water body with significant concentrations of chlorophyll, particulates and chromophoric dissolved organic matter (CDOM) that highly impact the shape of reflectance spectra. Finally, past and ongoing research efforts provided an expensive data set of optical observations that support the goal of this project.

Harding, Lawrence W., Jr.