Reports From Four International Clinical Trials for Cancers of the Cervix, Uterus and Vulva, and a New Guideline for Cervical Cancer
No abstract prepared.
62 RADIOLOGY AND NUCLEAR MEDICINE↗
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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.
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Validating Modern NRG Oncology Pelvic Nodal and Groupe Francophone de Radiothérapie Urologique Prostate Bed Contouring Guidelines for Post-Prostatectomy Salvage Radiation: A Secondary Analysis of the LOCATE Trial
We used the patterns of recurrence on {sup 18}F-fluciclovine positron emission tomography (PET)–computed tomography (CT) in patients enrolled in the LOCATE trial after prostatectomy to evaluate how well the most recent NRG Oncology and Groupe Francophone de Radiothérapie Urologique (GFRU) contouring recommendations encompassed all sites of recurrence in the prostate fossa and pelvic nodes in comparison to former Radiation Therapy Oncology Group (RTOG) recommendations.
62 RADIOLOGY AND NUCLEAR MEDICINE↗
Unlocking multiphysics design guidelines on Si/C composite nanostructures for high-energy-density and robust lithium-ion battery anode
In general, current material fabrication guidance for novel designs of Si/C composite particle materials focuses on electrochemical behavior and redox reactions at the nano/micro level. However, such guidance cannot provide detailed information for predicting mechanical deformations of the composite particles, especially when the mechanical field coupled with electrochemical and thermal fields. Here, we establish an electro-chemo-mechanical model and implement it to quantitatively analyze the multiphysics behavior of five representative Si/C composite nanostructures. Modeling and computation discover that yolk-shell and dual-shell structures are more robust in terms of particle fractures. When considering electrochemical performance, the yolk-shell structure is the best among the compared five Si/C composites. Finally, we map design guidance to further illustrate quantitative structure-property relationships. This study provides novel insights on Si/C composite nanostructure anode material design and additional powerful design tools for next-generation high-energy-density lithium-ion batteries.
25 ENERGY STORAGE↗
Toxicity reference values for force health protection: Provisional occupational exposure guidelines
Not Available
Sweeney, Lisa M. (ORCID:0000000246727358)↗
Carbon Capture: Theoretical Guidelines for Activated Carbon-Based CO 2 Adsorption Material Evaluation
Not Available
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗
From Data to Structure: Guidelines for Trustworthy SAXS Interpretation in Energy-Related Systems
Explore the source record for details and available documents.
Wu, Shiwen↗
Valorisation of technical lignin in rigid polyurethane foam: A critical evaluation on trends, guidelines and future perspectives
Lignin is one of the most abundant aromatic natural polymers. Produced as a by-product from the biomass refinery industries, lignin remains largely underutilised in high-value industrial applications. The incorporation of lignin in rigid polyurethane foam (RPUF) has been the focus of much research, due to its potential to replace fossil fuel-based components of RPUF. However, the overall sustainability of RPUF depends on numerous factors including processability, cost-effectiveness, and retention of performance throughout the service life. To date, the incorporation of lignin has been explored either as filler particles (through direct incorporation) or as a blendable liquid polyol introduced after chemical modifications (such as oxyalkylation, functionalisation, or depolymerisation). However, the production of lignin incorporated foam with high performance through cost-effective processing is still an ongoing challenge. Herein, this review critically appraises the progress on the effective incorporation of lignin in RPUF. Firstly, this review briefly covers the essential raw materials, formulation, important properties, and sustainability aspects of RPUF for industrial applications. Secondly, it provides insights on the key parameters of lignin of relevance to incorporation into RPUF. Thirdly, it benchmarks the reported studies on incorporation of lignin in RPUF systems by evaluating their important properties and proposes potential strategies for addressing the key challenges in the incorporation of lignin in RPUF. By bridging the gaps that exist in the literature on the utilisation of lignin in RPUF this account will serve as a resource for both beginners and professionals in the polyurethane and biorefinery industries towards the successful development of lignin incorporated RPUF for industrial applications
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗
Correlation function metrology for warm dense matter: Recent developments and practical guidelines
X-ray Thomson scattering (XRTS) has emerged as a valuable diagnostic for matter under extreme conditions, as it captures the intricate many-body physics of the probed sample. Recent advances, such as the model-free temperature diagnostic of Dornheim et al. [Nat. Commun. 13 , 7911 (2022)], have demonstrated how much information can be extracted directly within the imaginary-time formalism. However, since the imaginary-time formalism is a concept often difficult to grasp, we provide here a systematic overview of its theoretical foundations and explicitly demonstrate its practical applications to temperature inference, including relevant subtleties. Furthermore, we present recent developments that enable the determination of the absolute normalization, Rayleigh weight, and density from XRTS measurements without reliance on uncontrolled model assumptions. Finally, we outline a unified workflow that guides the extraction of these key observables, offering a practical framework for applying the method to interpret experimental measurements.
70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
A multimodal and integrated approach to interrogate human kidney biopsies with rigor and reproducibility: guidelines from the Kidney Precision Medicine Project
Comprehensive and spatially mapped molecular atlases of organs at a cellular level are a critical resource to gain insights into pathogenic mechanisms and personalized therapies for diseases. The Kidney Precision Medicine Project (KPMP) is an endeavor to generate three-dimensional (3-D) molecular atlases of healthy and diseased kidney biopsies by using multiple state-of-the-art omics and imaging technologies across several institutions. Obtaining rigorous and reproducible results from disparate methods and at different sites to interrogate biomolecules at a single-cell level or in 3-D space is a significant challenge that can be a futile exercise if not well controlled. Here we describe a “follow the tissue” pipeline for generating a reliable and authentic single-cell/region 3-D molecular atlas of human adult kidney. Our approach emphasizes quality assurance, quality control, validation, and harmonization across different omics and imaging technologies from sample procurement, processing, storage, shipping to data generation, analysis, and sharing. We established benchmarks for quality control, rigor, reproducibility, and feasibility across multiple technologies through a pilot experiment using common source tissue that was processed and analyzed at different institutions and different technologies. A peer review system was established to critically review quality control measures and the reproducibility of data generated by each technology before their being approved to interrogate clinical biopsy specimens. The process established economizes the use of valuable biopsy tissue for multiomics and imaging analysis with stringent quality control to ensure rigor and reproducibility of results and serves as a model for precision medicine projects across laboratories, institutions and consortia.
59 BASIC BIOLOGICAL SCIENCES↗
GHEP WIBT (Guidelines for Home Energy Professionals Weatherization Installer Badges Toolkit) [SWR-20-69]
The National Renewable Energy Laboratory (NREL) and the U.S. Department of Energy's (DOE) Weatherization Assistance Program (WAP) are collaborating with the home energy retrofit industry to support the development of skilled workers. The Installer Badges Toolkit provides a flexible, customizable, and voluntary approach to training and skills recognition for WAP implementers, utility programs, private-sector workers, and contractors. In Fiscal Year 2018, DOE, along with the Crew Leader scheme committee, determined the Retrofit Installer Technician (RIT) Job Task Analysis (JTA) could be eliminated and its tasks inserted in the Crew Leader JTA. The RIT tasks became the basis of the Installer Badges. The Badges Toolkit was updated in 2020 to add licensing and copyright agreements. Users must cite the copyright information when using or distributing copies of the Badges Toolkit in any way. The technical content has remained unchanged from previous versions of the Badges Toolkit. The Toolkit for home retrofits consists of 25 Badges, each representing different energy efficiency tasks that an installer could perform on a home. Each Badge defines the desired outcome, criteria to verify, applicable material requirements, and references to Standard Work Specifications (SWS) or other relevant standards. The Badges provide a consistent approach to training by ensuring that installers in different regions are learning the same skills nationwide. Organizations can also customize the Toolkit by choosing only those Badges that are relevant to their program. The Badges Toolkit includes five pieces: "How to Use the Badges Toolkit" provides a brief overview of how a Grantee, Subgrantee, or training provider may approach using the toolkit. The "Badges Toolkit: Worksheet" includes what to consider when determining whether and how to best incorporate the Badges into a weatherization assistance program. The "Crew Leader Job Task Analysis Spreadsheet" indicates how the Badges align with specific areas of the JTA. The "Installer Badges Passport" features separate pages for each Badge, which include places for the installer and the supervisor/trainer to record the number of times a task has been successfully completed. The "Installer Badges Verification Criteria" includes sample inspection checklists for each Badge. These can be modified as needed based on approved variance requests or more stringent requirements. They also provide a basis for consistent inspections and awarding of Badges. Note: All elements of the Badges Toolkit are designed for use by potential program implementers. They are not off-the-shelf products intended for immediate deployment. Program implementers must review and modify as needed, revise verification criteria to match local requirements, complete worksheets, and otherwise define the parameters of their own badging program.
Desai, Jal↗
Monitoring, Reporting, and Verification Plan (MRV)- Meeting EPA Guidelines for GHGRP and Subpart RR
This report summarizes the process and work completed to develop and successfully submit an MRV plan to EPA. This work used the lessons learned from various MRCSP tasks to demonstrate the geologic understanding of the Niagaran reefs, successful monitoring and accounting methodologies, understanding of potential risks and leakage pathways, and mass balance of CO2 baseline and net storage. The plan currently encompasses 10 reefs and also provides a reporting plan for future reef development.
accounting↗
Design & Brand Guidelines (V.1.03)
The goal is to revitalize the Lab’s identity so that it reflects a focused and forward-looking approach to solving national security challenges. This goal is achieved through design that is dynamic, accessible, and optimized for 21st century communications.
96 KNOWLEDGE MANAGEMENT AND PRESERVATION↗
Recruitment Brand Guidelines (V.0.2)
The goal is to revitalize the Lab’s identity so that it reflects a focused and forward-looking approach to solving national security challenges. This goal is achieved through design that is dynamic, accessible, and optimized for 21st century communications.
99 GENERAL AND MISCELLANEOUS↗
Monitoring, Reporting, and Verification (MRV) Plan - Meeting EPA Guidelines for GHGRP and Subpart RR
The Midwest Regional Carbon Sequestration Partnership (MRCSP) was founded in 2003 as part of the U.S. Department of Energy’s (DOE’s) Regional Carbon Sequestration Partnership initiative. Since its founding, MRCSP has made significant strides toward making CCUS a viable option for states in the region. The public/private consortium, funded through the DOE Regional Carbon Sequestration Initiative, brings together nearly 40 industry partners and 10 states. Battelle, as the project lead, oversees research, development and operations and coordinates activities among the partners. The incremental, phased approach has built a valuable knowledge base for the industry and paved the way for commercial-scale adoption of CCUS technologies. From 2008 to 2020, MRCSP Phase III focused on the development of large-scale injection projects. This report is part of a series of reports prepared under the Midwestern Regional Carbon Sequestration Partnership (MRCSP) Phase III (Development Phase). These reports summarize and detail the findings of the work conducted under the Phase III project. This report summarizes the steps for successfully submitting a Monitoring, Reporting and Verification (MRV) plan to the U.S. Environmental Protection Agency (EPA). This work used the lessons learned from various MRCSP tasks to demonstrate the geologic understanding of the reefs in Northern Niagaran Pinnacle Reef Trend (NNPRT), successful monitoring and accounting methodologies, understanding of potential risks and leakage pathways, and mass balance of CO2 baseline and net storage. The plan encompasses ten reefs and provides a reporting plan for future reef development.
01 COAL, LIGNITE, AND PEAT↗