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At least 109 records · Page 6

Scaling features of noncoding DNA

We review evidence supporting the idea that the DNA sequence in genes containing noncoding regions is correlated, and that the correlation is remarkably long range--indeed, base pairs thousands of base pairs distant are correlated. We do not find such a long-range correlation in the coding regions of the gene, and utilize this fact to build a Coding Sequence Finder Algorithm, which uses statistical ideas to locate the coding regions of an unknown DNA sequence. Finally, we describe briefly some recent work adapting to DNA the Zipf approach to analyzing linguistic texts, and the Shannon approach to quantifying the "redundancy" of a linguistic text in terms of a measurable entropy function, and reporting that noncoding regions in eukaryotes display a larger redundancy than coding regions. Specifically, we consider the possibility that this result is solely a consequence of nucleotide concentration differences as first noted by Bonhoeffer and his collaborators. We find that cytosine-guanine (CG) concentration does have a strong "background" effect on redundancy. However, we find that for the purine-pyrimidine binary mapping rule, which is not affected by the difference in CG concentration, the Shannon redundancy for the set of analyzed sequences is larger for noncoding regions compared to coding regions.

Non-NASA Center↗

The effect of a redundant color code on an overlearned identification task

The possibility of finding redundancy gains with overlearned tasks was examined using a paradigm varying familiarity with the stimulus set. Redundant coding in a multidimensional stimulus was demonstrated to result in increased identification accuracy and decreased latency of identification when compared to stimuli varying on only one dimension. The advantages attributable to redundant coding are referred to as redundancy gain and were found for a variety of stimulus dimension combinations, including the use of hue or color as one of the dimensions. Factors that have affected redundancy gain include the discriminability of the levels of one stimulus dimension and the level of stimulus-to-response association. The results demonstrated that response time is in part a function of familiarity, but no effect of redundant color coding was demonstrated. Implications of research on coding in identification tasks for display design are discussed.

Obrien, Kevin↗

Local performance optimization for a class of redundant eight-degree-of-freedom manipulators

Local performance optimization for joint limit avoidance and manipulability maximization (singularity avoidance) is obtained by using the Jacobian matrix pseudoinverse and by projecting the gradient of an objective function into the Jacobian null space. Real-time redundancy optimization control is achieved for an eight-joint redundant manipulator having a three-axis spherical shoulder, a single elbow joint, and a four-axis spherical wrist. Symbolic solutions are used for both full-Jacobian and wrist-partitioned pseudoinverses, partitioned null-space projection matrices, and all objective function gradients. A kinematic limitation of this class of manipulators and the limitation's effect on redundancy resolution are discussed. Results obtained with graphical simulation are presented to demonstrate the effectiveness of local redundant manipulator performance optimization. Actual hardware experiments performed to verify the simulated results are also discussed. A major result is that the partitioned solution is desirable because of low computation requirements. The partitioned solution is suboptimal compared with the full solution because translational and rotational terms are optimized separately; however, the results show that the difference is not significant. Singularity analysis reveals that no algorithmic singularities exist for the partitioned solution. The partitioned and full solutions share the same physical manipulator singular conditions. When compared with the full solution, the partitioned solution is shown to be ill-conditioned in smaller neighborhoods of the shared singularities.

Williams, Robert L., II↗

X-wing fly-by-wire vehicle management system

A complete, computer based, vehicle management system (VMS) for X-Wing aircraft using digital fly-by-wire technology controlling many subsystems and providing functions beyond the classical aircraft flight control system. The vehicle management system receives input signals from a multiplicity of sensors and provides commands to a large number of actuators controlling many subsystems. The VMS includes--segregating flight critical and mission critical factors and providing a greater level of back-up or redundancy for the former; centralizing the computation of functions utilized by several subsystems (e.g. air data, rotor speed, etc.); integrating the control of the flight control functions, the compressor control, the rotor conversion control, vibration alleviation by higher harmonic control, engine power anticipation and self-test, all in the same flight control computer (FCC) hardware units. The VMS uses equivalent redundancy techniques to attain quadruple equivalency levels; includes alternate modes of operation and recovery means to back-up any functions which fail; and uses back-up control software for software redundancy.

Fischer, Jr., William C.↗

Survey of space flight safety systems.

Preventive and remedial conceptual approaches may be employed to enhance the safety of space flight operations. The preventive approach makes use of components of high reliability and the incorporation of redundancy in crew safety-related functions. According to the second conceptual approach the means are to be provided to cope with accidents when they arise. The remedial means include onboard systems, pre-positioned aids, and earth-launched systems. Reports or papers dealing with rescue and survival systems of various types are considered, and a summary of the results of space escape, rescue, and survivability investigations is presented.

Fleisig, R.↗

A new approach to long-life noncontacting electromechanical devices

Brushless dc motors are finding increasing application in space. Likewise, with the advent of the light emitting diode, noncontacting encoders are gradually replacing sliding contact types. The direct drive concept has proved its merit and is now the preferred approach for tape recorders and low to moderate torque instrument drives. The final step in this evolution is the magnetic bearing, which now appears feasible for several applications. Where it can be applied in a totally noncontacting system, life and reliability will be a function of the electronic controls, where redundancy, derating, and quality assurance approaches virtually assure the desired lifetime and failure rate.

Devine, E. J.↗

Management of information in a research and development agency

The NASA program for managing scientific and technical information (STI) is examined, noting the technological, managerial, educational, and legal aspects of transferring and disseminating information. A definition of STI is introduced and NASA's STI-related management programs are outlined. Consideration is given to the role of STI management in NASA mission programs, research efforts supporting the management and use of STI, STI program interfaces, and the Automated Information Management Program to eliminate redundant automation efforts in common administrative functions. The infrastructure needed to manage the broad base of NASA information and the interfaces between NASA's STI management and external organizations are described.

Keene, Wallace O.↗

Management of information in a research and development agency

The NASA program for managing scientific and technical information (STI) is examined, noting the technological, managerial, educational, and legal aspects of transferring and disseminating information. A definition of STI is introduced and NASA's STI-related management programs are outlined. Consideration is given to the role of STI management in NASA mission programs, research efforts supporting the management and use of STI, STI program interfaces, and the Automated Information Management Program to eliminate redundant automation efforts in common administrative functions. The infrastructure needed to manage the broad base of NASA information and the interfaces between NASA's STI management and external organizations are described.

Keene, Wallace O.↗

Fault Management Techniques in Human Spaceflight Operations

This paper discusses human spaceflight fault management operations. Fault detection and response capabilities available in current US human spaceflight programs Space Shuttle and International Space Station are described while emphasizing system design impacts on operational techniques and constraints. Preflight and inflight processes along with products used to anticipate, mitigate and respond to failures are introduced. Examples of operational products used to support failure responses are presented. Possible improvements in the state of the art, as well as prioritization and success criteria for their implementation are proposed. This paper describes how the architecture of a command and control system impacts operations in areas such as the required fault response times, automated vs. manual fault responses, use of workarounds, etc. The architecture includes the use of redundancy at the system and software function level, software capabilities, use of intelligent or autonomous systems, number and severity of software defects, etc. This in turn drives which Caution and Warning (C&W) events should be annunciated, C&W event classification, operator display designs, crew training, flight control team training, and procedure development. Other factors impacting operations are the complexity of a system, skills needed to understand and operate a system, and the use of commonality vs. optimized solutions for software and responses. Fault detection, annunciation, safing responses, and recovery capabilities are explored using real examples to uncover underlying philosophies and constraints. These factors directly impact operations in that the crew and flight control team need to understand what happened, why it happened, what the system is doing, and what, if any, corrective actions they need to perform. If a fault results in multiple C&W events, or if several faults occur simultaneously, the root cause(s) of the fault(s), as well as their vehicle-wide impacts, must be determined in order to maintain situational awareness. This allows both automated and manual recovery operations to focus on the real cause of the fault(s). An appropriate balance must be struck between correcting the root cause failure and addressing the impacts of that fault on other vehicle components. Lastly, this paper presents a strategy for using lessons learned to improve the software, displays, and procedures in addition to determining what is a candidate for automation. Enabling technologies and techniques are identified to promote system evolution from one that requires manual fault responses to one that uses automation and autonomy where they are most effective. These considerations include the value in correcting software defects in a timely manner, automation of repetitive tasks, making time critical responses autonomous, etc. The paper recommends the appropriate use of intelligent systems to determine the root causes of faults and correctly identify separate unrelated faults.

O'Hagan, Brian↗

Refined Gearbox Design for the Chariot Lunar Rover

In planning for NASA's return to the moon by the year 2020, the NASA Johnson Space Center (JSC) designed and built a lunar concept vehicle called Chariot. Slightly larger than a pickup truck, it was designed to demonstrate similar utilitarian functions, but with twelve wheels for redundancy, reliability, and reduced surface contact pressure. JSC designed a motor gearbox to drive each of Chariot s six wheel pods. The pods can be independently steered over 360 for maneuverability. This paper describes the design of a second generation, drop-in replacement gearbox. The new design has a lower parts count, and is lighter than the original, which represents a step toward flight hardware.

Bauman, Steve↗

Two is One, One is None: A Discussion on Redundancy

Redundancy is the duplication of critical components or functions of a system with the intention of increasing reliability of the system, usually in the form of a backup or fail-safe. But the topic of redundancy can be a contentious topic; what is too little, too much, and just right may not be readily apparent. This presentation will be a discussion on redundancy situations from different industries as well as the evolving nature of the “best” amount of redundancy.

Redundancy↗

Apollo experience report: Real-time auxiliary computing facility development

The Apollo real time auxiliary computing function and facility were an extension of the facility used during the Gemini Program. The facility was expanded to include support of all areas of flight control, and computer programs were developed for mission and mission-simulation support. The scope of the function was expanded to include prime mission support functions in addition to engineering evaluations, and the facility became a mandatory mission support facility. The facility functioned as a full scale mission support activity until after the first manned lunar landing mission. After the Apollo 11 mission, the function and facility gradually reverted to a nonmandatory, offline, on-call operation because the real time program flexibility was increased and verified sufficiently to eliminate the need for redundant computations. The evaluation of the facility and function and recommendations for future programs are discussed in this report.

Allday, C. E.↗

Vehicle management and mission planning in support of shuttle operations.

An operational approach to shuttle mission planning during high flight frequency years (20 or more flights per year) is described wherein diverse mission planning functions interface via an interactive computer system and common data base. The Vehicle Management and Mission Planning System (VMMPS) is proposed as a means of helping to accomplish the mission planning function. The VMMPS will link together into an interactive system the major mission planning areas such as trajectory, crew, vehicle performance, and launch operations. A common data base will be an integral part of the system and the concept of standard mission types and phases will be used to minimize mission to mission uniqueness. The use of this system will eliminate much redundancy and replanning, shorten interface times between functions, and provide a means to evaluate unplanned events and modify schedules.

Pruett, W. R.↗

The Apollo VHF ranging system

As the Apollo program proceeded, redundancy became a requirement for all crew safety functions. One critical period of the Apollo missions was the rendezvous of the Command Module and the Lunar Module. The rendezvous radar provided the critical range, range rate, and angle measurements necessary to complete the rendezvous. Use of a redundant radar for backup was out of the question because of its 80-lb weight. It was, however, found that the voice radios could be adapted to perform the ranging function. Slight modifications of the VHF voice radios and the addition of a ranging interrogator and transponder at a weight of less than 10 lbs total would provide an accuracy of 100-ft rms at several hundred miles. The Apollo VHF ranging system demonstrated that it is feasible to achieve highly accurate range measurements with conventional voice radios.

Nossen, E. J.↗

Radiation Tolerant Intelligent Memory Stack (RTIMS)

The Radiation Tolerant Intelligent Memory Stack (RTIMS), suitable for both geostationary and low earth orbit missions, has been developed. The memory module is fully functional and undergoing environmental and radiation characterization. A self-contained flight-like module is expected to be completed in 2006. RTIMS provides reconfigurable circuitry and 2 gigabits of error corrected or 1 gigabit of triple redundant digital memory in a small package. RTIMS utilizes circuit stacking of heterogeneous components and radiation shielding technologies. A reprogrammable field programmable gate array (FPGA), six synchronous dynamic random access memories, linear regulator, and the radiation mitigation circuitries are stacked into a module of 42.7mm x 42.7mm x 13.00mm. Triple module redundancy, current limiting, configuration scrubbing, and single event function interrupt detection are employed to mitigate radiation effects. The mitigation techniques significantly simplify system design. RTIMS is well suited for deployment in real-time data processing, reconfigurable computing, and memory intensive applications.

Ng, Tak-kwong↗

The P prime(f) to N(h) inversion problem in ionospheric soundings

A general review is given of the inversion techniques used to derive the ionospheric electron density N as a function of altitude h from group path P versus frequency f measurements obtained by vertical incidence ionospheric sounders. The paper discusses the medium under investigation, the experimental techniques used to obtain the P(f) data, the theoretical considerations leading to the integral equation relating P(f) to N(h), and the assumptions made in the inversion process. The lamination inversion technique is then presented, with special attention given to mathematical difficulties arising from discontinuities in the P(f) function, infinities in the integrand, and in some cases unknown integration limits. Methods outlined for minimizing the uncertainties due to discontinuities include the use of redundant information - that is the two distinct P(f) functions available for a given N(h) profile - and the use of models based on statistical data. Mathematical procedures are discussed that increase significantly the efficiency and accuracy of the required numerical integrations. The accuracy of the inversion technique is deduced by comparing the resulting N(h) profile with N(h) data obtained by simultaneous but independent observations.

Jackson, J. E.↗

Statistical and linguistic features of DNA sequences

We present evidence supporting the idea that the DNA sequence in genes containing noncoding regions is correlated, and that the correlation is remarkably long range--indeed, base pairs thousands of base pairs distant are correlated. We do not find such a long-range correlation in the coding regions of the gene. We resolve the problem of the "non-stationary" feature of the sequence of base pairs by applying a new algorithm called Detrended Fluctuation Analysis (DFA). We address the claim of Voss that there is no difference in the statistical properties of coding and noncoding regions of DNA by systematically applying the DFA algorithm, as well as standard FFT analysis, to all eukaryotic DNA sequences (33 301 coding and 29 453 noncoding) in the entire GenBank database. We describe a simple model to account for the presence of long-range power-law correlations which is based upon a generalization of the classic Levy walk. Finally, we describe briefly some recent work showing that the noncoding sequences have certain statistical features in common with natural languages. Specifically, we adapt to DNA the Zipf approach to analyzing linguistic texts, and the Shannon approach to quantifying the "redundancy" of a linguistic text in terms of a measurable entropy function. We suggest that noncoding regions in plants and invertebrates may display a smaller entropy and larger redundancy than coding regions, further supporting the possibility that noncoding regions of DNA may carry biological information.

Non-NASA Center↗

Current limiting remote power control module

The power source for the Space Station Freedom will be fully utilized nearly all of the time. As such, any loads on the system will need to operate within expected limits. Should any load draw an inordinate amount of power, the bus voltage for the system may sag and disrupt the operation of other loads. To protect the bus and loads some type of power interface between the bus and each load must be provided. This interface is most crucial when load faults occur. A possible system configuration is presented. The proposed interface is the Current Limiting Remote Power Controller (CL-RPC). Such an interface should provide the following power functions: limit overloading and resulting undervoltage; prevent catastrophic failure and still provide for redundancy management within the load; minimize cable heating; and provide accurate current measurement. A functional block diagram of the power processing stage of a CL-RPC is included. There are four functions that drive the circuit design: rate control of current; current sensing; the variable conductance switch (VCS) technology; and the algorithm used for current limiting. Each function is discussed separately.

Hopkins, Douglas C.↗