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NASA NTRS2012

Linked Open Data in the Global Change Information System (GCIS)

The U.S. Global Change Research Program (http://globalchange.gov) coordinates and integrates federal research on changes in the global environment and their implications for society. The USGCRP is developing a Global Change Information System (GCIS) that will centralize access to data and information related to global change across the U.S. federal government. The first implementation will focus on the 2013 National Climate Assessment (NCA) . (http://assessment.globalchange.gov) The NCA integrates, evaluates, and interprets the findings of the USGCRP; analyzes the effects of global change on the natural environment, agriculture, energy production and use, land and water resources, transportation, human health and welfare, human social systems, and biological diversity; and analyzes current trends in global change, both human-induced and natural, and projects major trends for the subsequent 25 to 100 years. The NCA has received over 500 distinct technical inputs to the process, many of which are reports distilling and synthesizing even more information, coming from thousands of individuals around the federal, state and local governments, academic institutions and non-governmental organizations. The GCIS will present a web-based version of the NCA including annotations linking the findings and content of the NCA with the scientific research, datasets, models, observations, etc. that led to its conclusions. It will use semantic tagging and a linked data approach, assigning globally unique, persistent, resolvable identifiers to all of the related entities and capturing and presenting the relationships between them, both internally and referencing out to other linked data sources and back to agency data centers. The developing W3C PROV Data Model and ontology will be used to capture the provenance trail and present it in both human readable web pages and machine readable formats such as RDF and SPARQL. This will improve visibility into the assessment process, increase understanding and reproducibility, and ultimately increase credibility and trust of the resulting report. Building on the foundation of the NCA, longer term plans for the GCIS include extending these capabilities throughout the U.S. Global Change Research Program, centralizing access to global change data and information across the thirteen agencies that comprise the program.

Tilmes, Curt A.↗

NASA NTRS2019

DNA Damage Response to Low and High-LET in a Large Cohort of Mice and Humans and Latest Advancement in NASA Space Omics

This presentation will first focus on a thorough evaluation of the DNA damage response to both low and high-LET in a cohort of 76 mice primary skin fibroblast derived from 15 different strains or in human blood mononuclear cells derived from 550 healthy donors. In both the human and mice work, we have hypothesized that DNA repair capacity can be used as a marker to evaluate and differentiate individual radiation sensitivity. More specifically, this work is based on the concept that the combined time-dose dependence of radiation-induced foci (RIF) of p53-binding protein 1 (53BP1) following low-LET exposure contains sufficient information to infer sensitivity to any other LET. This work is one of the most extensive studies on the kinetics and possible genetic underpinnings of radiation-induced DNA damage and repair. Results on humans are still preliminary as we are still in the process of collecting and isolating primary blood mononuclear cells from 500 to 800 healthy subjects of European descent, 18-75 years of age, 50/50 male/female distribution. We have analyzed 53BP1+ RIF formation as well as oxidative stress and cell death in primary cells from 192 subjects in response to the same HZE particles as used in mice: 600 MeV/n Fe, 350 MeV/n Ar and 350 MeV/n Si, 1.1 and 3 particles/100m2, 4 and 24 hours after irradiation. The second part of the talk will focus on describing GeneLab: The NASA Systems Biology Platform for Space Omics Repository, Analysis and Visualization. NASA GeneLab is an open-access repository for omics datasets generated by biological experiments conducted in space or experiments relevant to spaceflight (e.g. simulated cosmic radiation, simulated microgravity, bed rest studies). Started as a repository designed to archive precious omics from space experiments, GeneLab has expanded its scope to maximize the intelligibility of the raw data (e.g. RNAseq, microarray, WGBS, metagenome), particularly for users with limited bioinformatics knowledge. As such GeneLab is now providing processed data derived from the raw data covering a large spectrum of omics (genome, epigenome, transcriptome, epitranscriptome, proteome, metabolome), to help users explore important questions: Which genes or proteins are expressed differently in space for various living organisms? What are the consequences arising from these changes? What specifics DNA mutations or epigenetic changes happen in space? What species or genetic features lead to better adaption to such a unique environment? In this presentation, we will report on the current and future objectives for GeneLab, and review recent published studies relating molecular changes observed in various animal models and tissue with microgravity, radiation, circadian rhythm, hydration and carbon dioxide conditions.

DNA repair kinetics↗

NASA NTRS1993

Study on the biological effect of cosmic radiation and the development of radiation protection technology (L-11)

NASDA is now participating in a series of flight experiments on Spacelab missions. The first experiment was carried out on the first International Microgravity Laboratory Mission (IML-1) January 1992, and the second experiment will be conducted on the Spacelab-J Mission, First Materials Processing Test (FMPT). The equipment or Radiation Monitoring Container Devices (RMCD) includes passive dosimeter systems and biological specimens. The experiments using this hardware are designed by NASDA to measure and investigate the radiation levels inside spacecraft like space shuttle and to look at the basic effects of the space environment from the aspect of radiation biology. The data gathered will be analyzed to understand the details of biological effects as well as the physical nature of space radiation registered in the sensitive Solid-State Track Detectors (SSTD).

Nagaoka, Shunji↗

NASA NTRS1995

Advanced Biotelemetry Systems for Space Life Sciences: PH Telemetry

The SENSORS 2000! (S2K!) program at NASA's Ames Research Center is currently developing a biotelemetry system for monitoring pH and temperature in unrestrained subjects. This activity is part of a broader scope effort to provide an Advanced Biotelemetry System (ABTS) for use in future space life sciences research. Many anticipated research endeavors will require biomedical and biochemical sensors and related instrumentation to make continuous inflight measurements in a variable-gravity environment. Since crew time is limited, automated data acquisition, data processing, data storage, and subject health monitoring are required. An automated biochemical and physiological data acquisition system based on non invasive or implantable biotelemetry technology will meet these requirements. The ABTS will ultimately acquire a variety of physiological measurands including temperature, biopotentials (e.g. ECG, EEG, EMG, EOG), blood pressure, flow and dimensions, as well as chemical and biological parameters including pH. Development activities are planned in evolutionary, leveraged steps. Near-term activities include 1) development of a dual channel pH/temperature telemetry system, and 2) development of a low bandwidth, 4-channel telemetry system, that measures temperature, heart rate, pressure, and pH. This abstract describes the pH/temperature telemeter.

Hines, John W.↗

NASA NTRS1992

The EOS Data and Information System (EOSDIS)

The Earth Observing System (EOS) is the centerpiece of NASA's Mission to Planet Earth initiative. It is a pivotal part of the U.S. Global Change Research Program and hence of the international effort to understand global change and the increasing demands of human activity. EOS consists of a space-based observing system, a Data and Information System (EOSDIS) and a scientific research program. The space component consists of two series of polar-orbiting spacecraft, the first scheduled for launch in 1998, that will collect data for 15 years. EOS is completing its conceptual design phase and is preparing to enter the design phase with the selection and construction of the instruments for the first platform. EOSDIS will allow researchers to quickly and easily access data about the Earth system. Development of EOSDIS has already begun; it will support research and analysis with existing data. Geophysical and biological products will be created from the satellite data to be used to a broad range of the scientific community. NASA has also committed to providing smaller missions - called Earth Probes - dedicated to near-term observations of specific Earth processes. The scientific research program was initiated in 1990, with funding for 28 interdisciplinary teams, to begin development of models that will use EOS data and define the data requirements from the instruments, nine facility instruments and their science teams, 23 instrument investigations and definition studies for a synthetic-aperture radar.

Dozier, J.↗

NASA NTRS1984

Satellite land remote sensing advancements for the eighties; Proceedings of the Eighth Pecora Symposium, Sioux Falls, SD, October 4-7, 1983

Among the topics discussed are NASA's land remote sensing plans for the 1980s, the evolution of Landsat 4 and the performance of its sensors, the Landsat 4 thematic mapper image processing system radiometric and geometric characteristics, data quality, image data radiometric analysis and spectral/stratigraphic analysis, and thematic mapper agricultural, forest resource and geological applications. Also covered are geologic applications of side-looking airborne radar, digital image processing, the large format camera, the RADARSAT program, the SPOT 1 system's program status, distribution plans, and simulation program, Space Shuttle multispectral linear array studies of the optical and biological properties of terrestrial land cover, orbital surveys of solar-stimulated luminescence, the Space Shuttle imaging radar research facility, and Space Shuttle-based polar ice sounding altimetry.

Source record↗

NASA NTRS1999

SIMBIOS Project 1998 Annual Report

The purpose of this series of technical reports is to provide current documentation of the Sensor Intercomparison and Merger for Biological and Interdisciplinary Ocean Studies (SIMBIOS) Project activities, NASA Research Announcement (NRA) research status, satellite data processing, data product validation and field calibration. This documentation is necessary to ensure that critical information is related to the scientific community and NASA management. This critical information includes the technical difficulties and challenges of combining ocean color data from an array of independent satellite systems to form consistent and accurate global bio-optical time series products. This technical report is not meant to substitute for scientific literature. Instead, it will provide a ready and responsive vehicle for the multitude of technical reports issues by an operational project.

McClain, Charles R.↗

NASA NTRS1999

SIMBIOS Project 1999 Annual Report

The purpose of this technical memorandum is to provide current documentation of the Sensor Intercomparison and Merger for Biological and Interdisciplinary Oceanic Studies (SIMBIOS) Project activities, NASA Research Announcement (NRA) research status, satellite data processing, data product validation, and field calibration. This documentation is necessary to ensure that critical information is related to the scientific community and NASA management. This critical information includes the technical difficulties and challenges of combining ocean color data from an array of independent satellite systems to form consistent and accurate global bio-optical time series products. This technical report is not meant as a substitute for scientific literature. Instead, it will provide a ready and responsive vehicle for the multitude of technical reports issued by an operational project.

McClain, Charles R.↗

NASA NTRS1977

A preliminary investigation of the Environmental Control and Life Support Subsystem (EC/LSS) for the space construction base manufacturing modules

The preliminary data of the environmental control and life support subsystem for a space construction base manufacturing module was reported. A space processing module, which is capable of performing production biological experiments, was chosen as a baseline configuration. The primary assemblies and components considered for use were humidity and temperature control, ventilation fan, cabin fan, water separator, condensate storage, overboard dumping, distribution system, contaminant monitoring, cabin sensors, and fire and smoke detection.

Wells, H. B.↗

NASA NTRS2012

Using the NASA Giovanni DICCE Portal to Investigate Land-Ocean Linkages with Satellite and Model Data

Data-enhanced Investigations for Climate Change Education (DICCE), a NASA climate change education project, employs the NASA Giovanni data system to enable teachers to create climate-related classroom projects using selected satellite and assimilated model data. The easy-to-use DICCE Giovanni portal (DICCE-G) provides data parameters relevant to oceanic, terrestrial, and atmospheric processes. Participants will explore land-ocean linkages using the available data in the DICCE-G portal, in particular focusing on temperature, ocean biology, and precipitation variability related to El Ni?o and La Ni?a events. The demonstration includes the enhanced information for educators developed for the DICCE-G portal. The prototype DICCE Learning Environment (DICCE-LE) for classroom project development will also be demonstrated.

Acker, James G.↗

NASA NTRS2001

SIMBIOS Project

The purpose of this technical report is to provide current documentation of the Sensor Intercomparison and Merger for Biological and Interdisciplinary Oceanic Studies (SIMBIOS) Project activities, NASA Research Announcement (NRAI) research status, satellite data processing, data product validation, and field calibration. This documentation is necessary to ensure that critical information is related to the scientific community and NASA management. This critical information includes the technical difficulties and challenges of validating and combining ocean color data from an array of independent satellite systems to form consistent and accurate global bio-optical time series products. This technical report is not meant as a substitute for scientific literature. Instead, it will provide a ready and responsive vehicle for the multitude of technical reports issued by an operational project.

Fargion, Giulietta S.↗

NASA NTRS2002

SIMBIOS Project

The purpose of this technical report is to provide current documentation of the Sensor Intercomparison and Merger for Biological and Interdisciplinary Oceanic Studies (SIMBIOS) Project activities, NASA Research Announcement (NRA) research status, satellite data processing, data product validation, and field calibration. This documentation is necessary to ensure that critical information is related to the scientific community and NASA management. This critical information includes the technical difficulties and challenges of validating and combining ocean color data from an array of independent satellite systems to form consistent and accurate global bio-optical time series products. This technical report is not meant as a substitute for scientific literature. Instead, it will provide a ready and responsive vehicle for the multitude of technical reports issued by an operational project. The SIMBIOS Science Team Principal Investigators' (PIs) original contributions to this report are in chapters four and above. The purpose of these contributions is to describe the current research status of the SIMBIOS-NRA-96 funded research. The contributions are published as submitted, with the exception of minor edits to correct obvious grammatical or clerical errors.

Fargion, Giulietta S.↗

NASA NTRS2002

Sources of Variability in Chlorophyll Analysis by Fluorometry and High-Performance Liquid Chromatography in a SIMBIOS Inter-Calibration Exercise

The purpose of this technical report is to provide current documentation of the Sensor Intercomparison and Merger for Biological and Interdisciplinary Oceanic Studies (SIMBIOS) Project activities, NASA Research Announcement (NRA) research status, satellite data processing, data product validation, and field calibration. This documentation is necessary to ensure that critical information is related to the scientific community and NASA management. This critical information includes the technical difficulties and challenges of validating and combining ocean color data from an array of independent satellite systems to form consistent and accurate global bio-optical time series products. This technical report is not meant as a substitute for scientific literature. Instead, it will provide a ready and responsive vehicle for the multitude of technical reports issued by an operational project. This particular document focus on the variability in chlorophyll pigment measurements resulting from differences in methodologies and laboratories conducting the pigment analysis.

VanHeukelem, Laurie↗

NASA NTRS2003

SIMBIOS Project; 2003 Annual Report

The purpose of this technical report is to provide current documentation of the the Sensor Intercomparison and Merger for Biological and Interdisciplinary Oceanic Studies (SIMBIOS) Project activities, NASA Research Announcement (NRA) research status, satellite data processing, data product validation, and field calibration. This documentation is necessary to ensure that critical information is related to the scientific community and NASA management. This critical information includes the technical difficulties and challenges of validating and combining ocean color data from an array of independent satellite systems to form consistent and accurate global bio-optical time series products. This technical report is not meant as a substitute for scientific literature. Instead, it will provide a ready and responsive vehicle for the multitude of technical reports issued by an operational project. The SIMBIOS Science Team Principal Investigators (PIs) original contributions to this report are in chapters four and above. The purpose of these contributions is to describe the current research status of the SIMBIOS-NRA-99 funded research. The contributions are published as submitted, with the exception of minor edits to correct obvious grammatical or clerical errors.

McClain, Charles R.↗

NASA NTRS2003

Semiselective Optoelectronic Sensors for Monitoring Microbes

Sensor systems are under development for use in real-time detection and quantitation of microbes in water without need for sampling. These systems include arrays of optical sensors; miniature, portable electronic data-acquisition circuits; and optoelectronic interfaces between the sensor arrays and data-acquisition circuits. These systems are intended for original use in long-term, inline monitoring of waterborne micro-organisms in water-reclamation systems aboard future spacecraft. They could also be adapted to similar terrestrial uses with respect to municipal water supplies, stored drinking water, and swimming water; for detecting low-level biological contamination in biotechnological, semiconductor, and pharmaceutical process streams; and in verifying the safety of foods and beverages. In addition, they could be adapted to monitoring of airborne microbes and of surfaces (e.g., to detect and/or quantitate biofilms). The designs of the sensors in these systems are based partly on those of sensors developed previously for monitoring airborne biological materials. The designs exploit molecular- recognition and fluorescence-spectroscopy techniques, such that in the presence of micro-organisms of interest, fluorescence signals change and the changes can be measured. These systems are characterized as semiselective because they respond to classes of micro-organisms and can be used to discriminate among the classes. This semiselectivity is a major aspect of the design: It is important to distinguish between (1) the principle of detection and quantitation of classes of micro-organisms by use of these sensors and (2) the principle of detection and quantitation of individual microbiological species by means of prior immuno-diagnostic and/or molecular-biology techniques. Detection of classes (in contradistinction to species) is particularly valuable when the exact nature of a contaminant is unknown.

Tabacco, Mary Beth↗

NASA NTRS1986

Architectures and algorithms for digital image processing; Proceedings of the Meeting, Cannes, France, December 5, 6, 1985

The conference presents papers on the architectures, algorithms, and applications of image processing. Particular attention is given to a very large scale integration system for image reconstruction from projections, a prebuffer algorithm for instant display of volume data, and an adaptive image sequence filtering scheme based on motion detection. Papers are also presented on a simple, direct practical method of sensing local motion and analyzing local optical flow, image matching techniques, and an automated biological dosimetry system.

Duff, Michael J. B.↗

NASA NTRS1998

The Mississippi NASA Community College Initiative

The object of this project was to provide greater utilization of existing resources to enhance the educational opportunities of Mississippi Community College students. When first introduced to the concept the teachers were understandably reluctant. They already had very heavy, prescribed work loads and most of what they had to do did not include NASA data. Teacher cooperation became a first goal. The second goal was effective use of NASA Earth Observation Data at every campus. Some compromises had to be made. The goal became to create a methodology or system that could be used on every campus and that the teachers would use. First year Biology was taught from a state-level prescribed curriculum on every one of the fifteen campuses. However, using Earth Observation Data in that curriculum was difficult. A compromise was made that allowed us to focus, in the first year, on the lesson hosting and creation process. Ten of the thirteen participating teachers agreed to create future lessons. They also asked to have a Community College Science Symposium in the Spring to demonstrate their lessons to the other science teachers in the state.

Lawhead, Pamela B.↗

NASA NTRS1998

End-to-End Data System Architecture for the Space Station Biological Research Project

The Space Station Biological Research Project (SSBRP) Is developing hardware referred to as the "facility" for providing life sciences research capability on the International Space Station. This hardware includes several biological specimen habitats, habitat holding racks, a centrifuge and a glovebox. An SSBRP end to end data system architecture has been developed to allow command and control of the facility from the ground, either with crew assistance or autonomously. The data system will be capable of handling commands, sensor data, and video from multiple cameras. The data will traverse through several onboard and ground networks and processing entities including the SSBRP and Space Station onboard and ground data systems. A large number of onboard and ground (,entities of the data system are being developed by the Space Station Program, other NASA centers and the International Partners. The SSBRP part of the system which includes the habitats, holding racks, and the ground operations center, User Operations Facility (UOF) will be developed by a multitude of geographically distributed development organizations. The SSBRP has the responsibility to define the end to end data and communications systems to make the interfaces manageable and verifiable with multiple contractors with widely varying development constraints and schedules. This paper provides an overview of the SSBRP end-to-end data system. Specifically, it describes the hardware, software and functional interactions of individual systems, and interface requirements among various entities of the end-to-end system.

Mian, Arshad↗