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At least 1,063 records · Page 59

Miniaturize the Redox Flow Battery for Accelerated Materials Discovery and Development

Redox flow batteries are a promising technology for grid-scale energy storage. The aqueous organic redox flow battery is of particular interest for its potentially low material cost and sustainability. Developing novel organic active material for flow battery electrolytes typically entails molecular engineering toward desired properties, necessitating organic synthesis. In a research laboratory setting, the synthesis of specifically designed organic molecules featuring targeted functional groups is time and resources intensive. In the past, synthesizing materials required for battery testing has often required gram-scale production, presenting considerable constraints on the pace of novel organic material discovery. In this report, we introduce a miniaturized cell design that mandates only milligram-scale material synthesis while yielding testing outcomes equivalent or superior to those reported with other commercially available or homemade flow cells in the literature. The test results under various pH conditions validate the scale-down strategy to accelerate the flow battery material discovery and development using the newly designed mini cell. This approach offers researchers an efficient means to notably reduce the time and resources required to develop novel materials for flow batteries.

25 ENERGY STORAGE↗

Graphical Environment Tools for Application to Gamma-Ray Energy Tracking Arrays (Final Report)

Highly segmented, position-sensitive germanium detector systems are being developed for nuclear physics research where traditional electronic signal processing with mixed analog and digital function blocks would be enormously complex and costly. Future systems will be constructed using pipelined processing of high-speed digitized signals as is done in the telecommunications industry. Techniques which provide rapid algorithm and system development for future systems are desirable. This project has used digital signal processing concepts and existing graphical system design tools to develop a set of re-usable modular functions and libraries targeted for the nuclear physics community. Researchers working with complex nuclear detector arrays such as the Gamma-Ray Energy Tracking Array (GRETA) have been able to construct advanced data processing algorithms for implementation in field programmable gate arrays (FPGAs) through application of these library functions using intuitive graphical interfaces.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Advanced Natural Gas Reciprocating Engine(s)

The objective of the Cummins ARES program, in partnership with the US Department of Energy (DOE), is to develop advanced natural gas engine technologies that increase engine system efficiency at lower emissions levels while attaining lower cost of ownership. The goals of the project are to demonstrate engine system achieving 50% Brake Thermal Efficiency (BTE) in three phases, 44%, 47% and 50% (starting baseline efficiency at 36% BTE) and 0.1 g/bhp-hr NOx system out emissions (starting baseline NOx emissions at 2 – 4 g/bhp-hr NOx). Primary path towards above goals include high Brake Mean Effective Pressure (BMEP), improved closed cycle efficiency, increased air handling efficiency and optimized engine subsystems. Cummins has successfully demonstrated each of the phases of this program. All targets have been achieved through application of a combined set of advanced base engine technologies and Waste Heat Recovery from Charge Air and Exhaust streams, optimized and validated on the demonstration engine and other large engines. The following architectures were selected for each Phase: Phase 1: Lean Burn Spark Ignited (SI) Key Technologies: High Efficiency Turbocharging, Higher Efficiency Combustion System. In production on the 60/91L engines. Over 500MW of ARES Phase 1 technology has been sold. Phase 2: Lean Burn Technology with Exhaust Waste Heat Recovery (WHR) System Key Technologies: Advanced Ignition System, Combustion Improvement, Integrated Waste Heat Recovery System. Base engine technologies intended for production within 2 to 3 years Phase 3: Lean Burn Technology with Exhaust and Charge Air Waste Heat Recovery System Key Technologies: Lower Friction, New Cylinder Head Designs, Improved Integrated Waste Heat Recovery System. Intended for production within 5 to 6 years Cummins is committed to the launch of next generation of large advanced NG engines based on ARES technology to be commercialized worldwide.

Pike, Edward↗

Muon Antineutrino Disappearance in the MINOS Experiment

Antineutrinos from the set of 7.09$\times 10^{20}$ Protons-on-target (POT) of $\nu_\mu\textrm{-dominant}$ and 3.40$\times 10^{20}$ POT of $\bar\nu_\mu\textrm{-enhanced}$ MINOS beam data is analysed to extract the antineutrino atmospheric-scale oscillation parameters $\left|\Delta\bar m^2\right|$ and $\sin^2\left(2\bar\theta\right)$. Using the Feldman-Cousins statistical technique to account for systematic and statistical errors, $\left|\Delta\bar m^2\right|=2.58^{+0.26}_{-0.17} \times 10^{-3}~\textrm{eV}^2$ and $\sin^2\left(2\bar\theta\right)=0.96^{+0.04}_{-0.10}$ were measured. This measurement of $\left|\Delta\bar m^2\right|$ improves on the previous world limits from Super-K by a factor of five. Any observed difference between the neutrino and antineutrino oscillation parameters could be an indication of CPT violation, or otherwise physics beyond the standard model. This measurement is consistent with the global limits on $\left|\Delta m^2\right|$ and $\sin^2\left(2\theta\right)$ for neutrinos.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Monte Carlo Hauser-Feshbach computer code system to model nuclear reactions: YAHFC

A computer program framework, YAHFC, to model low-energy nuclear reactions is presented. The framework allows for reactions with incident particles ranging from protons/neutrons to alphas and is designed to address reactions that ultimately lead to the formation of compound nuclear systems that then decay statistically as outlined in concepts of Hauser and Feshbach. Additionally, instead of a reaction, it is also possible to model the decay of a nuclear system with an initial excitation and population. The code models nuclear decays with a Monte Carlo process that tracks the decay of each state. This allows for an exact representation of the spectra for all emitted particles in each of the final exit channels and the possibility of generating reaction data for simulation purposes. The program is interfaced with the optical model code system FRESCOX to calculate transmission coefficients as well as the effects of coupled channels and other direct excitations via the distorted wave Born approximation (DWBA). Modules are included to account for nuclear processes such as width corrections, pre-equilibrium emission, and fission. The program is controlled by a series of input commands and while a set of input parameters exists for each projectile and target, the input commands allow for complete control over each input parameter. Extensive data files are produced and a program is provided that converts YAHFC data files into nuclear data library entries in the generalized nuclear data structure (GNDS).

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

RESIN: Responsible Innovation for Highly Recyclable Plastics - TASK 4: Risk Assessment Framework

This report covers the entirety of Task 4, but its main purpose is to deliver milestones ML4.4 and ML4.5, the last two SOPO milestones under Task 4. ML4.4 reports on the compatibility of polymer properties that affect both environmental performance and functional performance and the tradeoffs involved in turning these properties to the benefit of each. ML4.5 presents a complete set of information on the critical properties of benign target products, where benign products are defined as those with the shortest environmental lifetime which meet performance requirements. To support and provide context to the discussions of ML4.4 and ML4.5 and to provide a complete picture of Task 4, milestones 4.1-4.3 are briefly summarized at the beginning of the report. The discussion of ML4.4 introduces the notion of polymer persistence as a proxy for environmental risk. It then discusses the development and comparison of two machine leaning models explored for estimating polymer degradation rates, a random forest (RF) classifier and an RF regressor. Given the advantage of continuous outputs rather than simple classes, the RF regressor was incorporated in the Excel risk calculator, which to this point could implement the objectives of subtasks 4.1-4.3, estimating polymer release and redistribution. The ML4.4 discussion then addresses the effect of each of the three polymer features used by the RF regressor on polymer functional performance. These features are number molecular weight (Mn), glass transition temperature (T g ) and heat of fusion (H fus ). The discussion of ML4.5 reviews the conceptual framework of the risk model, which served as the foundation for developing the Excel risk calculator and describes the use of, and assumptions within, the calculator. Appendix A is further provided as a user’s guide for the calculator. To demonstrate how the calculator is intended to be used by developers in the design of low-risk polymers, an analysis of 27 hypothetical polymers defined by varying values for the three polymer features used by the RF regressor is presented. The range of parameter values selected produces estimates of polymer degradation rates and lifetimes that may be typical of various consumer products made from polyurethane polymers and shows how changes in polymer features affect lifetimes. The demonstration also predicts the final distribution of released polymer materials in environmental compartments as a function of consumer product mix and assumed leakage rates of end-of-life processes. Lastly, this report summarizes the achievement of Task 4 goals from original conception to final delivery and discusses how and to what degree to which each subtask goal was achieved.

36 MATERIALS SCIENCE↗

The Role of Specific Chemokines in the Amelioration of Colitis by Appendicitis and Appendectomy

The appendix contains abundant lymphoid tissue and is constantly exposed to gut flora. When completed at a young age, appendicitis followed by appendectomy (AA) prevents or significantly ameliorates Inflammatory Bowel Diseases (IBDs) in later life. Inflammatory bowel disease comprises Crohn’s disease and ulcerative colitis. Our murine AA model is the only existing experimental model of AA. In our unique model, AA performed in the most proximal colon limits colitis pathology in the most distal colon by curbing T-helper 17 cell activity, diminishing autophagy, modulating interferon activity-associated molecules, and suppressing endothelin vaso-activity-mediated immunopathology. In the research presented in this paper, we have examined the role of chemokines in colitis pathology with our murine AA model. Chemokines are a family of small cytokines with four conserved cysteine residues. Chemokines induce chemotaxis in adjacent cells with corresponding receptors. All 40 known chemokine genes and 24 chemokine receptor genes were examined for gene expression levels in distal colons three days post-AA and 28 days post-AA. At 28 days post-AA, the chemokine gene CCL5 was significantly upregulated. Furthermore, Gene Set Enrichment Analysis (GSEA) showed upregulation of seven CCL5-associated gene-sets 28 days post-AA in contrast to just one gene-set downregulated at the same time-point. The chemokine gene CXCL11 was significantly upregulated three days post-AA and 28 days post-AA. Evaluation using GSEA showed upregulation of six CXCL11-associated gene sets but no downregulation of any gene set. At 28 days post-AA, CCL17 gene expression was significantly downregulated. There was no expression of any chemokine receptor gene three days post-AA, but CCR10 was the only chemokine receptor gene that displayed differential gene expression (upregulation) 28 days post-AA. No CCR10-associated gene set was upregulated in GSEA in contrast to one downregulated gene set. Our analysis resulted in identifying three new therapeutic targets towards ameliorating colitis: CCL5, CXCL11, and CCL17. While CCL5 and CXCL11 are good therapeutic chemokine candidates to be exogenously administered, CCL17 is a good candidate chemokine to competitively inhibit or limit colitis pathology.

appendectomy, appendicities, chemokine, chemokine ↗

Longitudinal Antigenic Sequences and Sites from Intra-Host Evolution (LASSIE) identifies immune-selected HIV variants

Within-host genetic sequencing from samples collected over time provides a dynamic view of how viruses evade host immunity. Immune-driven mutations might stimulate neutralization breadth by selecting antibodies adapted to cycles of immune escape that generate within-subject epitope diversity. Comprehensive identification of immune-escape mutations is experimentally and computationally challenging. With current technology, many more viral sequences can readily be obtained than can be tested for binding and neutralization, making down-selection necessary. Typically, this is done manually, by picking variants that represent different time-points and branches on a phylogenetic tree. Such strategies are likely to miss many relevant mutations and combinations of mutations, and to be redundant for other mutations. Longitudinal Antigenic Sequences and Sites from Intrahost Evolution (LASSIE) uses transmitted founder loss to identify virus “hot-spots” under putative immune selection and chooses sequences that represent recurrent mutations in selected sites. LASSIE favors earliest sequences in which mutations arise. Here, with well-characterized longitudinal Env sequences, we confirmed selected sites were concentrated in antibody contacts and selected sequences represented diverse antigenic phenotypes. Finally, practical applications include rapidly identifying immune targets under selective pressure within a subject, selecting minimal sets of reagents for immunological assays that characterize evolving antibody responses, and for immunogens in polyvalent “cocktail” vaccines.

59 BASIC BIOLOGICAL SCIENCES↗

Numerical Methodology for Optimization of Compression-Ignited Engines Considering Combustion Noise Control

It is challenging to develop highly efficient and clean engines while meeting user expectations in terms of performance, comfort, and drivability. One of the critical aspects in this regard is combustion noise control. Combustion noise accounts for about 40 percent of the overall engine noise in typical turbocharged diesel engines. The experimental investigation of noise generation is difficult due to its inherent complexity and measurement limitations. Therefore, it is important to develop efficient numerical strategies in order to gain a better understanding of the combustion noise mechanisms. In this work, a novel methodology was developed, combining computational fluid dynamics (CFD) modeling and genetic algorithm (GA) technique to optimize the combustion system hardware design of a high-speed direct injection (HSDI) diesel engine, with respect to various emissions and performance targets including combustion noise. The CFD model was specifically set up to reproduce the unsteady pressure field inside the combustion chamber, thereby allowing an accurate prediction of the acoustic response of the combustion phenomena. The model was validated by simulating several steady operating conditions and comparing the numerical results against experimental data, in both temporal and frequency domains. Thereafter, a GA optimization was performed with the goal of minimizing indicated specific fuel consumption (ISFC) and combustion noise, while restricting pollutant (soot and NOx) emissions to their respective baseline values. Eight design variables were selected pertaining to piston bowl geometry, nozzle inclusion angle, number of injector nozzle holes, and in-cylinder swirl. An objective merit function (MF) based on the emissions, ISFC, and combustion noise was constructed to quantify the strength of the engine designs and was determined using the CFD model as the function evaluator. The in-cylinder noise level was characterized by the total resonance energy of local pressure oscillations. The optimum engine configuration thus obtained showed a significant improvement in terms of efficiency and combustion noise compared to the baseline system, along with both soot and NOx emissions within their respective constraints. This optimum configuration included a deeper and tighter bowl geometry with higher swirl and larger number of nozzle holes. Subsequently, a more detailed acoustics analysis based on proper orthogonal decomposition (POD) technique was carried out to further explore the combustion noise benefits achieved by the GA optimum. In conclusion, this computational study is a first of its kind (to the best of the authors’ knowledge), which demonstrates a comprehensive framework to incorporate combustion noise into a numerical optimization strategy for engine design.

42 ENGINEERING↗

Fast Machine Learning for Quantum Control of Microwave Qudits on Edge Hardware

Quantum optimal control is a promising approach to improve the accuracy of quantum gates, but it relies on complex algorithms to determine the best control settings. CPU or GPU-based approaches often have delays that are too long to be applied in practice. It is paramount to have systems with extremely low delays to quickly and with high fidelity adjust quantum hardware settings, where fidelity is defined as overlap with a target quantum state. Here, we utilize machine learning (ML) models to determine control-pulse parameters for preparing Selective Number-dependent Arbitrary Phase (SNAP) gates in microwave cavity qudits, which are multi-level quantum systems that serve as elementary computation units for quantum computing. The methodology involves data generation using classical optimization techniques, ML model development, design space exploration, and quantization for hardware implementation. Our results demonstrate the efficacy of the proposed approach, with optimized models achieving low gate trace infidelity near $10^{-3}$ and efficient utilization of programmable logic resources.

Sanders, Flor [Columbia U.]↗

Functional genomics of lipid metabolism in the oleaginous yeast Rhodosporidium toruloides

The basidiomycete yeast Rhodosporidium toruloides (also known as Rhodotorula toruloides) accumulates high concentrations of lipids and carotenoids from diverse carbon sources. It has great potential as a model for the cellular biology of lipid droplets and for sustainable chemical production. We developed a method for high-throughput genetics (RB-TDNAseq), using sequence-barcoded Agrobacterium tumefaciens T-DNA insertions. We identified 1,337 putative essential genes with low T-DNA insertion rates. We functionally profiled genes required for fatty acid catabolism and lipid accumulation, validating results with 35 targeted deletion strains. We identified a high-confidence set of 150 genes affecting lipid accumulation, including genes with predicted function in signaling cascades, gene expression, protein modification and vesicular trafficking, autophagy, amino acid synthesis and tRNA modification, and genes of unknown function. These results greatly advance our understanding of lipid metabolism in this oleaginous species and demonstrate a general approach for barcoded mutagenesis that should enable functional genomics in diverse fungi.

59 BASIC BIOLOGICAL SCIENCES↗

The evaluation of display symbology - A chronometric study of visual search

Three single-target visual search tasks were used to evaluate a set of CRT symbols for a helicopter traffic display. The search tasks were representative of the kinds of information extraction required in practice, and reaction time was used to measure the efficiency with which symbols could be located and identified. The results show that familiar numeric symbols were responded to more quickly than graphic symbols. The addition of modifier symbols such as a nearby flashing dot or surrounding square had a greater disruptive effect on the graphic symbols than the alphanumeric characters. The results suggest that a symbol set is like a list that must be learned. Factors that affect the time to respond to items in a list, such as familiarity and visual discriminability, and the division of list items into categories, also affect the time to identify symbols.

Remington, R.↗

On the selection and evaluation of visual display symbology Factors influencing search and identification times

Three single-target visual search tasks were used to evaluate a set of cathode-ray tube (CRT) symbols for a helicopter situation display. The search tasks were representative of the information extraction required in practice, and reaction time was used to measure the efficiency with which symbols could be located and identified. Familiar numeric symbols were responded to more quickly than graphic symbols. The addition of modifier symbols, such as a nearby flashing dot or surrounding square, had a greater disruptive effect on the graphic symbols than did the numeric characters. The results suggest that a symbol set is, in some respects, like a list that must be learned. Factors that affect the time to identify items in a memory task, such as familiarity and visual discriminability, also affect the time to identify symbols. This analogy has broad implications for the design of symbol sets. An attempt was made to model information access with this class of display.

Remington, Roger↗

ADRPM-VII applied to the long-range acoustic detection problem

An acoustic detection range prediction model (ADRPM-VII) has been written for IBM PC/AT machines running on the MS-DOS operating system. The software allows the user to predict detection distances of ground combat vehicles and their associated targets when they are involved in quasi-military settings. The program can also calculate individual attenuation losses due to spherical spreading, atmospheric absorption, ground reflection and atmospheric refraction due to temperature and wind gradients while varying parameters effecting the source-receiver problem. The purpose here is to examine the strengths and limitations of ADRPM-VII by modeling the losses due to atmospheric refraction and ground absorption, commonly known as excess attenuation, when applied to the long range detection problem for distances greater than 3 kilometers.

Shalis, Edward↗

Knowledge From Pictures (KFP)

The old maxim goes: 'A picture is worth a thousand words'. The objective of the research reported in this paper is to demonstrate this idea as it relates to the knowledge acquisition process and the automated development of an expert system's rule base. A prototype tool, the Knowledge From Pictures (KFP) tool, has been developed which configures an expert system's rule base by an automated analysis of and reasoning about a 'picture', i.e., a graphical representation of some target system to be supported by the diagnostic capabilities of the expert system under development. This rule base, when refined, could then be used by the expert system for target system monitoring and fault analysis in an operational setting. Most people, when faced with the problem of understanding the behavior of a complicated system, resort to the use of some picture or graphical representation of the system as an aid in thinking about it. This depiction provides a means of helping the individual to visualize the bahavior and dynamics of the system under study. An analysis of the picture augmented with the individual's background information, allows the problem solver to codify knowledge about the system. This knowledge can, in turn, be used to develop computer programs to automatically monitor the system's performance. The approach taken is this research was to mimic this knowledge acquisition paradigm. A prototype tool was developed which provides the user: (1) a mechanism for graphically representing sample system-configurations appropriate for the domain, and (2) a linguistic device for annotating the graphical representation with the behaviors and mutual influences of the components depicted in the graphic. The KFP tool, reasoning from the graphical depiction along with user-supplied annotations of component behaviors and inter-component influences, generates a rule base that could be used in automating the fault detection, isolation, and repair of the system.

Truszkowski, Walt↗

Design and development status of ETS-7, an RVD and space robot experiment satellite

ETS-7 (Engineering Test Satellite #7) is an experimental satellite for the in-orbit experiment of the Rendezvous Docking (RVD) and the space robot (RBT) technologies. ETS-7 is a set of two satellites, a chaser satellite and a target satellite. Both satellites will be launched together by NASDA's H-2 rocket into a low earth orbit. Development of ETS-7 started in 1990. Basic design and EM (Engineering Model) development are in progress now in 1994. The satellite will be launched in mid 1997 and the above in-orbit experiments will be conducted for 1.5 years. Design of ETS-7 RBT experiment system and development status are described in this paper.

Oda, M.↗

Method for Correcting Control Surface Angle Measurements in Single Viewpoint Photogrammetry

A method of determining a corrected control surface angle for use in single viewpoint photogrammetry to correct control surface angle measurements affected by wing bending. First and second visual targets are spaced apart &om one another on a control surface of an aircraft wing. The targets are positioned at a semispan distance along the aircraft wing. A reference target separation distance is determined using single viewpoint photogrammetry for a "wind off condition. An apparent target separation distance is then computed for "wind on." The difference between the reference and apparent target separation distances is minimized by recomputing the single viewpoint photogrammetric solution for incrementally changed values of target semispan distances. A final single viewpoint photogrammetric solution is then generated that uses the corrected semispan distance that produced the minimized difference between the reference and apparent target separation distances. The final single viewpoint photogrammetric solution set is used to determine the corrected control surface angle.

Burner, Alpheus W.↗

Low-Energy Elastic Electron Scattering by Atomic Oxygen

The B-spline R-matrix method is employed to investigate the low-energy elastic electron scattering by atomic oxygen. Flexible non-orthogonal sets of radial functions are used to construct the target description and to represent the scattering functions. A detailed investigation regarding the dependence of the predicted partial and total cross sections on the scattering model and the accuracy of the target description is presented. The predicted angle-integrated elastic cross sections are in good agreement with experiment, whereas significant discrepancies are found in the angle-differential elastic cross sections near the forward direction. .The near-threshold results are found to strongly depend on the treatment of inner-core short-range correlation effects in the target description, as well as on a proper account of the target polarizability. A sharp increase in the elastic cross sections below 1 eV found in some earlier calculations is judged to be an artifact of an unbalanced description of correlation in the N-electron target structure and the (N+l)-electron-collision problems.

Zatsarinny O.↗