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At least 1,063 records · Page 59
All sourcesNASA NTRSDOE OSTI
NASA NTRS1973

Sustained linear acceleration

The subjective effects of sustained acceleration are discussed, including positive, negative, forward, backward, and lateral acceleration effects. Physiological effects, such as retinal and visual response, unconsciousness and cerebral function, pulmonary response, and renal output, are studied. Human tolerance and performance under sustained acceleration are ascertained.

Fraser, T. M.↗
NASA NTRS1984

The Effect of Part-simulation of Weightlessness on Human Control of Bilateral Teleoperation: Neuromotor Considerations

The effect of weightlessness on the human operator's performance in force reflecting position control of remote manipulators was investigated. A gravity compensation system was developed to simulate the effect of weightlessness on the operator's arm. A universal force reflecting hand controller (FRHC) and task simulation software were employed. Two experiments were performed because of anticipated disturbances in neuromotor control specification on the human operator in an orbital control environment to investigate: (1) the effect of controller stiffness on the attainment of a learned terminal position in the three dimensional controller space, and (2) the effect of controller stiffness and damping on force tracking of the contour of a simulated three dimensional cube using the part simulation of weightless conditions. The results support the extension of neuromotor control models, which postulate a stiffness balance encoding of terminal position, to three dimensional motion of a multilink system, confirm the existence of a disturbance in human manual control performance under gravity compensated conditions, and suggest techniques for compensation of weightlessness induced performance decrement through appropriate specification of hand controller response characteristics. These techniques are based on the human control model.

Corker, K.↗
NASA NTRS1985

Image gathering and processing - Information and fidelity

In this paper we formulate and use information and fidelity criteria to assess image gathering and processing, combining optical design with image-forming and edge-detection algorithms. The optical design of the image-gathering system revolves around the relationship among sampling passband, spatial response, and signal-to-noise ratio (SNR). Our formulations of information, fidelity, and optimal (Wiener) restoration account for the insufficient sampling (i.e., aliasing) common in image gathering as well as for the blurring and noise that conventional formulations account for. Performance analyses and simulations for ordinary optical-design constraints and random scences indicate that (1) different image-forming algorithms prefer different optical designs; (2) informationally optimized designs maximize the robustness of optimal image restorations and lead to the highest-spatial-frequency channel (relative to the sampling passband) for which edge detection is reliable (if the SNR is sufficiently high); and (3) combining the informationally optimized design with a 3 by 3 lateral-inhibitory image-plane-processing algorithm leads to a spatial-response shape that approximates the optimal edge-detection response of (Marr's model of) human vision and thus reduces the data preprocessing and transmission required for machine vision.

Huck, F. O.↗
NASA NTRS1987

Space 2000: Meeting the challenge of a new era

The focus of the present book is on the variety of past and future human activities in space. NASA's response to the Challenger explosion is discussed and an overview is given of the agency's relations with foreign competitors in the 1980s. The practical uses of space are described with attention given to communications satellites, the orbital high ground (weather watching, spying, and SDI), earth science, and materials processing in space. Other topics include the exploration of the near and distant universe, and permanent stations in space and on the moon.

Shipman, Harry L.↗
NASA NTRS1990

A new six-degree-of-freedom force-reflecting hand controller for space telerobotics

A new 6 degree of freedom universal Force Reflecting Hand Controller (FRHC) was designed for use as the man-machine interface in teleoperated and telerobotic flight systems. The features of this new design include highly intuitive operation, excellent kinesthetic feedback, high fidelity force/torque feedback, a kinematically simple structure, mechanically decoupled motion in all 6 DOF, good back-drivability, and zero backlash. In addition, the new design has a much larger work envelope, smaller stowage volume, greater stiffness and responsiveness, and better overlap of the human operator's range of motion than do previous designs. The utility and basic operation of a new, flight prototype FRHC called the Model X is briefly discussed. The design heritage, general design goals, and design implementation of this advanced new generation of FRHCs are presented, followed by a discussion of basic features and the results of initial testing.

Mcaffee, Douglas↗
NASA NTRS1990

BUBBLES: an Automated Decision Support System for Final Approach Controllers

With the assumptions that an explicit schedule exists for landings (and takeoffs) at each runway, that each aircraft has declared an IAS for final approach and will be obligated to fly it as accurately as possible, and that there is a continuous estimate of average windspeed on approach, the objective was to provide automated cues to assist controllers in the spacing of landing aircraft. The cues have two characteristics. First, they are adaptive to estimation errors in position and speed by the radar tracking process and piloting errors in the execution of turns and commanded speed reductions. Second, the cues are responsive to the desires of the human controller. Several diagrams are used to help explain the system.

Chi, Zhizang↗
NASA NTRS1993

Intelligent data presentation for real-time spacecraft monitoring

This paper describes an intelligent user interface that is currently under development. The interface serves as a front end for real-time spacecraft monitoring software. The software operates under circumstances in which neither an intelligent human without automated assistance nor an automated system without intelligence are sufficiently effective. The user interface is supported by dynamic trade-off evaluation (DTE), a new technique that has been developed to automate general types of performance trade-offs in real-time problem solving systems. In this application, DTE is used to perform dynamic input data management for the purpose of determining which input data should be monitored in time constrained situations and how to present the monitoring information to a human analyst who has the ultimate responsibility for the spacecraft. This application has demonstrated that DTE can be used to dynamically vary the data that is monitored, making it possible to detect and correctly analyze all anomalous data by examining only a subset of the total input data. In carefully structured experimental evaluations that use real spacecraft data and real decision making, DTE provides the ability to handle a three-fold increase in input data (in real-time) without loss of performance and to intelligently present the information to a mission analyst.

Schwuttke, U. M.↗
NASA NTRS2002

Induction of chromatin damage and distribution of isochromatid breaks in human fibroblast cells exposed to heavy ions

The frequency of chromatid breaks and the distribution of isochromatid breaks were measured in G2-phase normal human fibroblasts prematurely condensed a short time after exposure to low- or high-LET radiations. The average number of isochromatid breaks from a single particle traversal increased with increasing LET values, while the average number of chromatid-type breaks appeared to reach a plateau. The distribution of isochromatid breaks after high-LET iron particles exposure was overdispersed compared to gamma-rays, indicating that a single iron particle traversal through a cell nucleus can produce multiple isochromatid breaks.

NASA Center JSC↗
NASA NTRS2002

A comparison of quality factors and weighting factors for characterizing astronaut radiation exposures

Radiation exposures are typically characterized by two quantities. The first is the absorbed dose, or the energy deposited per unit mass for specific types of radiation passing through specified materials. The same amount of energy deposited in material by two different types of radiation, however, can result in two different levels of risk. Because of this, for the purpose of radiation protection operations, absorbed dose is modified by a second factor intended to normalize the risk associated with a given exposure. We present here an inter-comparison of methods for this modification. First is the radiation quality factor (Q), as defined by ICRP publication 60. This quantity is related functionally to the unrestricted linear energy transfer (LET) of a given radiation, and is multiplied by the absorbed dose to derive the dose equivalent (H). The second method for modifying absorbed dose is the radiation weighting factor, also given in ICRP-60, or as modified in NCRP report 115. To implement the weighting factor, the absorbed dose resulting from incidence of a particular radiation is multiplied by a factor assigned to that type of radiation, giving the equivalent dose. We compare calculations done based on identical fields of radiation representative of that encountered by the MIR space station, applying each of these two methods. c2002 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

NASA Center JSC↗
NASA NTRS2002

Oxidative stress inhibits caveolin-1 palmitoylation and trafficking in endothelial cells

During normal and pathological conditions, endothelial cells (ECs) are subjected to locally generated reactive oxygen species, produced by themselves or by other vessel wall cells. In excess these molecules cause oxidative injury to the cell but at moderate levels they might modulate intracellular signalling pathways. We have investigated the effect of oxidative stress on the palmitoylation and trafficking of caveolin-1 in bovine aortic ECs. Exogenous H2O2 did not alter the intracellular localization of caveolin-1 in ECs. However, metabolic labelling experiments showed that H2O2 inhibited the trafficking of newly synthesized caveolin-1 to membrane raft domains. Several mechanisms potentially responsible for this inhibition were examined. Impairment of caveolin-1 synthesis by H2O2 was not responsible for diminished trafficking. Similarly, the inhibition was independent of H2O2-induced caveolin-1 phosphorylation as shown by the markedly different concentration dependences. We tested the effect of H2O2 on palmitoylation of caveolin-1 by the incorporation of [3H]palmitic acid. Exposure of ECs to H2O2 markedly inhibited the palmitoylation of caveolin-1. Comparable inhibition was observed after treatment of cells with H2O2 delivered either as a bolus or by continuous delivery with glucose and glucose oxidase. Kinetic studies showed that H2O2 did not alter the rate of caveolin-1 depalmitoylation but instead decreased the 'on-rate' of palmitoylation. Together these results show for the first time the modulation of protein palmitoylation by oxidative stress, and suggest a cellular mechanism by which stress might influence caveolin-1-dependent cell activities such as the concentration of signalling proteins and cholesterol trafficking.

NASA Discipline Cell Biology↗