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At least 1,045 records · Page 58

Integrated atomistic chemical imaging and reactive force field molecular dynamic simulations on silicon oxidation

In this paper, we quantitatively investigate with atom probe tomography, the effect of temperature on the interfacial transition layer suboxide species due to the thermal oxidation of silicon. The chemistry at the interface was measured with atomic scale resolution, and the changes in chemistry and intermixing at the interface were identified on a nanometer scale. We find an increase of suboxide (SiOx) concentration relative to SiO{sub 2} and increased oxygen ingress with elevated temperatures. Our experimental findings are in agreement with reactive force field molecular dynamics simulations. This work demonstrates the direct comparison between atom probe derived chemical profiles and atomistic-scale simulations for transitional interfacial layer of suboxides as a function of temperature.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

Onboard utilization of ground control points for image correction. Volume 3: Ground control point simulation software design

The software developed to simulate the ground control point navigation system is described. The Ground Control Point Simulation Program (GCPSIM) is designed as an analysis tool to predict the performance of the navigation system. The system consists of two star trackers, a global positioning system receiver, a gyro package, and a landmark tracker.

Source record↗

Probabilistic Inference of Low-Surface-Brightness Galaxy Morphological Parameters Using Simulation-Based Inference

Low-surface-brightness galaxies (LSBGs) are diffuse, often dark-matter-dominated systems whose faintness makes their structural parameters difficult to measure reliably in wide-field imaging surveys. Robust parameter inference, including uncertainty quantification, is important for population studies and for comparisons with models of galaxy formation, as future surveys are expected to produce increasingly large samples of diffuse galaxies. In practice, LSBG profile modeling is sensitive to sky- background errors, masking choices, contaminating background sources, and the computational cost of obtaining posterior-level uncertainties for large samples. Motivated by these questions, we develop a simulation-based inference (SBI) framework for estimating posterior distributions of LSBG morphological parameters from simulated galaxy images. Using PyImfit, we generate DES-like single-Sersic profile LSBG images with known position angle, ellipticity, Sersic index, effective surface brightness, and effective radius. We then train a normalizing-flow-based neural posterior estimator using the sbi package to infer these parameters from the simulated images. For isolated simulated galaxies, the SBI posterior recovers the true input parameters, produces posterior predictive residuals consistent with the assumed noise model, and shows good empirical calibration in a DES-motivated test regime. We also compare SBI with PyImfit-based MCMC inference and find broadly comparable posterior constraints, while SBI enables substantially faster posterior sampling after training. Finally, we test robustness to compact background contaminants. A model trained only on isolated galaxies produces undercovered posteriors on contaminated images, whereas training on simulations with variable contaminant positions and fluxes improves calibration across contaminated test sets. These results demonstrate the promise of SBI for scalable, uncertainty-aware LSBG morphology inference, while emphasizing that posterior reliability strongly depends on whether training simulations include relevant observational complications.

Batbayar, Bilguun [U. Chicago (main)]↗

Electron image contrast analysis of mosaicity in rutile nanocrystals using direct electron detection

Direct electron detection provides high detective quantum efficiency, significantly improved point spread function and fast read-out which have revolutionized the field of cryogenic electron microscopy. However, these benefits for high-resolution electron microscopy (HREM) are much less exploited, especially for in situ study where major impacts on crystallographic structural studies could be made. By using direct detection in electron counting mode, rutile nanocrystals have been imaged at high temperature inside an environmental transmission electron microscope. The improvements in image contrast are quantified by comparison with a charge-coupled device (CCD) camera and by image matching with simulations using an automated approach based on template matching. Together, these approaches enable a direct measurement of 3D shape and mosaicity (~1°) of a vacuum-reduced TiO 2 nanocrystal about 50 nm in size. Thus, this work demonstrates the possibility of quantitative HREM image analysis based on direct electron detection.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

A Wind Tunnel Investigation of a Small Scale Tiltrotor Model in Descending Flight

A small-scale tiltrotor model was tested in the 7-by 10-foot Wind Tunnel at NASA Ames Research Center, with the goal of better understanding Vortex Ring State (VRS) effects on tiltrotor aircraft. Test objectives were to obtain performance data of a tiltrotor model over a wide range of descent conditions, to explore the effects of sideslip at these descent conditions, and to investigate the validity of using a single-rotor with a physical image plane to simulate dual rotor performance characteristics. The model consisted of a pair of 2-bladed teetering rotors with untwisted, 11.125-inch diameter, rectangular planform blades. Model configuration variations included a dual-rotor, an isolated-rotor, and a single-rotor with a physical image plane. Rotor performance data were obtained for the dual-rotor configuration operating over a wide range of descent and sideslip conditions. Isolated-rotor and single-rotor with image plane configurations were tested over an abbreviated range of descent conditions. Results of this investigation are presented and show mean thrust reductions in the region of VRS for each model configuration. In comparison with the dual-rotor configuration, the isolated-rotor and single-rotor with image plane configurations produced thrust results similar in trend but different in magnitude.

Abrego, Anita I.↗

SU-D-210-06: Feasibility for Monitoring the Head of the Pancreas Motion Through a Surrogate Using Ultrasound During Radiation Therapy Delivery

Purpose: Substantial target motion during the delivery of radiation therapy (RT) for pancreatic cancer is well recognized as a major limiting factor on RT effectiveness. The aim of this work is to monitor intra-fractional motion of the pancreas using ultrasound during RT delivery. Methods: Transabdominal Ultrasound B-mode images were collected from 5 volunteers using a research version of the Clarity Autoscan System (Elekta). The autoscan transducer with center frequency of 5 MHz was utilized for the scans. Imaging parameters were adjusted to acquire images at the desired depth with good contrast and a wide sweep angle. Since well-defined boundaries of the pancreas can be difficult to find on ultrasound B-mode images, the portal vein was selected as a surrogate for motion estimation of the head of the pancreas. The selection was due to its anatomical location posterior to the neck of the pancreas and close proximity to the pancreas head. The portal vein was contoured on the ultrasound images acquired during simulation using the Clarity Research AFC Workstation software. Volunteers were set up in a similar manner to the simulation for their monitoring session and the ultrasound transducer was mounted on an arm fixed to the couch. A video segment of the portal vein motion was captured. Results: The portal vein was visualized and segmented. Successful monitoring sessions of the portal vein were observed. In addition, our results showed that the ultrasound transducer itself reduces breathing related motion. This is analogous to the use of a compression plate to suppress respiration motion during thorax or abdominal irradiation. Conclusion: We demonstrate the feasibility of tracking the pancreas through the localization of the portal vein using abdominal ultrasound. This will allow for real-time tracking of the intra-fractional motion to justify PTV-margin and to account for unusual motions, thus, improving normal tissue sparing. This research was funding in part by Elekta Inc.

60 APPLIED LIFE SCIENCES↗

Adaptive snakes - Control of damping and material parameters

The stability of active contour models or 'snakes' is studied. It is shown that the modification of snake parameters using adaptive systems improves both the stability of the snakes and the boundaries obtained. The adaptive snakes perform better with images of varying contrasts, noisy images and images with different curvatures along the boundaries. The computational costs at each iteration for the adaptive snakes is still of order N, where N is the number of points on the snakes. Comparisons of the results for non-adaptive and adaptive snakes are shown using both computer simulations and satellite images.

Samadani, Ramin↗

SU-C-9A-06: The Impact of CT Image Used for Attenuation Correction in 4D-PET

Purpose: To evaluate the appropriateness of using 3D non-gated CT image for attenuation correction (AC) in a 4D-PET (gated PET) imaging protocol used in radiotherapy treatment planning simulation. Methods: The 4D-PET imaging protocol in a Siemens PET/CT simulator (Biograph mCT, Siemens Medical Solutions, Hoffman Estates, IL) was evaluated. CIRS Dynamic Thorax Phantom (CIRS Inc., Norfolk, VA) with a moving glass sphere (8 mL) in the middle of its thorax portion was used in the experiments. The glass was filled with {sup 18}F-FDG and was in a longitudinal motion derived from a real patient breathing pattern. Varian RPM system (Varian Medical Systems, Palo Alto, CA) was used for respiratory gating. Both phase-gating and amplitude-gating methods were tested. The clinical imaging protocol was modified to use three different CT images for AC in 4D-PET reconstruction: first is to use a single-phase CT image to mimic actual clinical protocol (single-CT-PET); second is to use the average intensity projection CT (AveIP-CT) derived from 4D-CT scanning (AveIP-CT-PET); third is to use 4D-CT image to do the phase-matched AC (phase-matching- PET). Maximum SUV (SUVmax) and volume of the moving target (glass sphere) with threshold of 40% SUVmax were calculated for comparison between 4D-PET images derived with different AC methods. Results: The SUVmax varied 7.3%±6.9% over the breathing cycle in single-CT-PET, compared to 2.5%±2.8% in AveIP-CT-PET and 1.3%±1.2% in phasematching PET. The SUVmax in single-CT-PET differed by up to 15% from those in phase-matching-PET. The target volumes measured from single- CT-PET images also presented variations up to 10% among different phases of 4D PET in both phase-gating and amplitude-gating experiments. Conclusion: Attenuation correction using non-gated CT in 4D-PET imaging is not optimal process for quantitative analysis. Clinical 4D-PET imaging protocols should consider phase-matched 4D-CT image if available to achieve better accuracy.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Investigating the limits of PET/CT imaging at very low true count rates and high random fractions in ion-beam therapy monitoring

Purpose: External beam radiotherapy with protons and heavier ions enables a tighter conformation of the applied dose to arbitrarily shaped tumor volumes with respect to photons, but is more sensitive to uncertainties in the radiotherapeutic treatment chain. Consequently, an independent verification of the applied treatment is highly desirable. For this purpose, the irradiation-induced β{sup +}-emitter distribution within the patient is detected shortly after irradiation by a commercial full-ring positron emission tomography/x-ray computed tomography (PET/CT) scanner installed next to the treatment rooms at the Heidelberg Ion-Beam Therapy Center (HIT). A major challenge to this approach is posed by the small number of detected coincidences. This contribution aims at characterizing the performance of the used PET/CT device and identifying the best-performing reconstruction algorithm under the particular statistical conditions of PET-based treatment monitoring. Moreover, this study addresses the impact of radiation background from the intrinsically radioactive lutetium-oxyorthosilicate (LSO)-based detectors at low counts. Methods: The authors have acquired 30 subsequent PET scans of a cylindrical phantom emulating a patientlike activity pattern and spanning the entire patient counting regime in terms of true coincidences and random fractions (RFs). Accuracy and precision of activity quantification, image noise, and geometrical fidelity of the scanner have been investigated for various reconstruction algorithms and settings in order to identify a practical, well-suited reconstruction scheme for PET-based treatment verification. Truncated listmode data have been utilized for separating the effects of small true count numbers and high RFs on the reconstructed images. A corresponding simulation study enabled extending the results to an even wider range of counting statistics and to additionally investigate the impact of scatter coincidences. Eventually, the recommended reconstruction scheme has been applied to exemplary postirradiation patient data-sets. Results: Among the investigated reconstruction options, the overall best results in terms of image noise, activity quantification, and accurate geometrical recovery were achieved using the ordered subset expectation maximization reconstruction algorithm with time-of-flight (TOF) and point-spread function (PSF) information. For this algorithm, reasonably accurate (better than 5%) and precise (uncertainty of the mean activity below 10%) imaging can be provided down to 80 000 true coincidences at 96% RF. Image noise and geometrical fidelity are generally improved for fewer iterations. The main limitation for PET-based treatment monitoring has been identified in the small number of true coincidences, rather than the high intrinsic random background. Application of the optimized reconstruction scheme to patient data-sets results in a 25% − 50% reduced image noise at a comparable activity quantification accuracy and an improved geometrical performance with respect to the formerly used reconstruction scheme at HIT, adopted from nuclear medicine applications. Conclusions: Under the poor statistical conditions in PET-based treatment monitoring, improved results can be achieved by considering PSF and TOF information during image reconstruction and by applying less iterations than in conventional nuclear medicine imaging. Geometrical fidelity and image noise are mainly limited by the low number of true coincidences, not the high LSO-related random background. The retrieved results might also impact other emerging PET applications at low counting statistics.

60 APPLIED LIFE SCIENCES↗

Asymmetric nanoparticle oxidation observed in-situ by the evolution of diffraction contrast

Abstract The use of transmission electron microscopy (TEM) to observe real-time structural and compositional changes has proven to be a valuable tool for understanding the dynamic behavior of nanomaterials. However, identifying the nanoparticles of interest typically require an obvious change in position, size, or structure, as compositional changes may not be noticeable during the experiment. Oxidation or reduction can often result in subtle volume changes only, so elucidating mechanisms in real-time requires atomic-scale resolution or in-situ electron energy loss spectroscopy, which may not be widely accessible. Here, by monitoring the evolution of diffraction contrast, we can observe both structural and compositional changes in iron oxide nanoparticles, specifically the oxidation from a wüstite-magnetite (FeO@Fe 3 O 4 ) core – shell nanoparticle to single crystalline magnetite, Fe 3 O 4 nanoparticle. The in-situ TEM images reveal a distinctive light and dark contrast known as the ‘Ashby-Brown contrast’, which is a result of coherent strain across the core – shell interface. As the nanoparticles fully oxidize to Fe 3 O 4 , the diffraction contrast evolves and then disappears completely, which is then confirmed by modeling and simulation of TEM images. This represents a new, simplified approach to tracking the oxidation or reduction mechanisms of nanoparticles using in-situ TEM experiments.

36 MATERIALS SCIENCE↗

The Identification and Modeling of Visual Cue Usage in Manual Control Task Experiments

Many fields of endeavor require humans to conduct manual control tasks while viewing a perspective scene. Manual control refers to tasks in which continuous, or nearly continuous, control adjustments are required. Examples include flying an aircraft, driving a car, and riding a bicycle. Perspective scenes can arise through natural viewing of the world, simulation of a scene (as in flight simulators), or through imaging devices (such as the cameras on an unmanned aerospace vehicle). Designers frequently have some degree of control over the content and characteristics of a perspective scene; airport designers can choose runway markings, vehicle designers can influence the size and shape of windows, as well as the location of the pilot, and simulator database designers can choose scene complexity and content. Little theoretical framework exists to help designers determine the answers to questions related to perspective scene content. An empirical approach is most commonly used to determine optimum perspective scene configurations. The goal of the research effort described in this dissertation has been to provide a tool for modeling the characteristics of human operators conducting manual control tasks with perspective-scene viewing. This is done for the purpose of providing an algorithmic, as opposed to empirical, method for analyzing the effects of changing perspective scene content for closed-loop manual control tasks.

Sweet, Barbara Townsend↗

Signatures of asymmetry in neutron spectra and images predicted by three-dimensional radiation hydrodynamics simulations of indirect drive implosions

We present the results of 3D simulations of indirect drive inertial confinement fusion capsules driven by the “high-foot” radiation pulse on the National Ignition Facility. The results are post-processed using a semi-deterministic ray tracing model to generate synthetic deuterium-tritium (DT) and deuterium-deuterium (DD) neutron spectra as well as primary and down scattered neutron images. Results with low-mode asymmetries are used to estimate the magnitude of anisotropy in the neutron spectra shift, width, and shape. Comparisons of primary and down scattered images highlight the lack of alignment between the neutron sources, scatter sites, and detector plane, which limits the ability to infer the ρr of the fuel from a down scattered ratio. Further calculations use high bandwidth multi-mode perturbations to induce multiple short scale length flows in the hotspot. The results indicate that the effect of fluid velocity is to produce a DT neutron spectrum with an apparently higher temperature than that inferred from the DD spectrum and which is also higher than the temperature implied by the DT to DD yield ratio.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

A study of image quality for radar image processing

Methods developed for image quality metrics are reviewed with focus on basic interpretation or recognition elements including: tone or color; shape; pattern; size; shadow; texture; site; association or context; and resolution. Seven metrics are believed to show promise as a way of characterizing the quality of an image: (1) the dynamic range of intensities in the displayed image; (2) the system signal-to-noise ratio; (3) the system spatial bandwidth or bandpass; (4) the system resolution or acutance; (5) the normalized-mean-square-error as a measure of geometric fidelity; (6) the perceptual mean square error; and (7) the radar threshold quality factor. Selective levels of degradation are being applied to simulated synthetic radar images to test the validity of these metrics.

King, R. W.↗

Identifying crack tip position and stress intensity factors from displacement data

Fracture prognosis and characterization efforts require knowledge of crack tip position and the Stress Intensity Factors (SIFs) acting in the vicinity of the crack. Here, in this work, we present an efficient numerical approach to infer both of these characteristics under a consistent theoretical framework from noisy, unstructured displacement data. The novel approach utilizes the separability of the asymptotic linear elastic fracture mechanics fields to expedite the search for crack tip position and is particularly useful for noisy displacement data. The manuscript begins with an assessment of the importance of accurately locating crack tip position when quantifying the SIFs from displacement data. Next, the proposed separability approach for quickly inferring crack tip position is introduced. Comparing to the widely used displacement correlation approach, the performance of the separability approach is assessed. Cases involving both noisy data and systematic deviation from the asymptotic linear elastic fracture mechanics model are considered, e.g. inelastic material behavior and finite geometries. An open source python implementation of the proposed approach is available for use by those doing field and laboratory work involving digital image correlation and simulations, e.g. finite element, discrete element, molecular dynamics and peridynamics, where the crack tip position is not explicitly defined.

36 MATERIALS SCIENCE↗

A quadrant-CCD star tracker

The characteristics of a quadrant-CCD designed for pointing and tracking are discussed with reference to its use in an adaptive optics program. The quadrant-CCD is used to correct stellar image motion proceeding from atmospheric turbulence by means of a system in which a sensor measures the image offset and sends data to a high-speed tip/tilt mirror. The design and control of the device are detailed, including four 100-micron-square pixels, the quadrant architecture, controller electronics, and data acquisition computer and interface. The transfer function is set forth in the x and y directions, and transfer curves are shown. A laboratory simulation of random image motion was conducted to evaluate the performance of the quadrant-CCD as an image motion sensor, and the experimental results are presented. The suitability of the quadrant-CCD for space-based pointing and tracking uses is demonstrated by this test and two earlier theoretical studies. Some future developments which improve performance capabilities are mentioned.

Clampin, M.↗

Soft X-Ray Imaging of Earth's Dayside Magnetosheath and Cusps Using Hybrid Simulations

Interactions between solar wind ions and neutral hydrogen atoms in Earth's exosphere can lead to the emission of soft X-rays. Upcoming missions such as SMILE and LEXI aim to use soft X-ray imaging to study the global structure of the magnetosphere. Although the magnetosheath and dayside magnetopause can often be driven by kinetic physics, it has typically been omitted from fluid simulations used to predict X-ray emissions. We study the possible results of soft X-ray imaging using hybrid simulations under quasi-radial interplanetary magnetic fields, where ion-ion instabilities drive ultra-low frequency foreshock waves, leading to turbulence in the magnetosheath, affecting the dynamics of the cusp and magnetopause. We simulate soft X-ray emission to determine what may be seen by missions such as LEXI, and evaluate the possibility of identifying kinetic structures. While kinetic structures are visible in high-cadence imaging, current instruments may not have the time resolution to discern kinetic signals.

J Ng↗