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At least 1,045 records · Page 58

Fan Beam Emission Tomography Demonstrated Successfully in the Reduced-Gravity Environment of Drop Towers

Fires onboard manned spacecraft and launch vehicles are a particularly feared hazard because one cannot jump ship while in orbit 240 nmi above the Earth at 17 000 mph! Understanding the physical properties of fires in free fall and on orbit is, therefore, a very important endeavor for NASA s Human Exploration and Development of Space (HEDS) enterprise. However, detailed information concerning the structure of microgravity fires remained elusive until recently since robustness, limited power, limited volume, and limited mass place severe constraints on diagnostic equipment for use in space and in NASA Glenn Research Center s reduced-gravity facilities. Under NASA Research Associate funding since 2001, En'Urga, Inc. (Dr. Sivathanu, principal investigator, and Dr. Lim, co-investigator) in collaboration with Glenn (Dr. Feikema, coinvestigator) have successfully demonstrated a new technology for use in microgravity combustion. A midinfrared scanning spectrometer has been developed by En'Urga and tested at Glenn to measure 30 spectra per second at different spatial locations in a flame from 1.8 to 4.8 microns.

Feikema, Douglas A.↗

Tomography of a Gamma-ray Burst Progenitor and its Host Galaxy

We have obtained near-infrared and high-resolution optical spectroscopy of the bright afterglow of the very intense gamma-ray burst recorded on 2002, October 4 (GRB 021004). Besides of line emission in the near-IR allowing an independent measurement of the systemic redshift (z = 2.3304 plus or minus 0.0005), we find several absorption line groups spanning a range of about 3,000 kilometers per second in velocity relative to the redshift of the host galaxy. The absorption profiles are very complex with both velocity-broadened components extending over several 100 kilometers per second and narrow lines with velocity widths of only approximately 20 kilometers per second. By analogy with QSO absorption line studies, the relative velocities, widths, and degrees of ionization of the lines ("line-locking", "ionization-velocity correlation") show that the progenitor had both an extremely strong radiation field and several distinct mass loss phases (winds). These results are consistent with GRB progenitors being massive stars, such as Luminous Blue Variables (LBVs) or Wolf-Rayet stars, providing a detailed picture of the spatial and velocity structure of the GRB progenitor star at the time of explosion. The host galaxy is a prolific star-forming galaxy with a SFR of approximately 10 solar mass yr(sup -l).

Castro-Tirado, Alberto J.↗

On the Feasibility of Satellite Altimeter Tomography

The time-varying field of sea surface height (SSH) reflects a large number of dynamical processes including a broad range of baroclinic waves. Inertia-gravity (IG) and Rossby waves (RW) are readily detected in power spectra F(k) of SSH spatial variations, as well as in wavenumber-frequency spectral, ,k), and autocorrelation functions W(). these statistical characteristics contain information on dynamical processes in the upper thermocline. We show that the well-known 3-segment shape of 1-d spectra (based on SSH variations along satellite tracks) is determined by the Internal Rossby radius of deformation and by the degree of nonlinearity of baroclinic IG waves. Analyzing altimeter-based spectra of SSH variations in the light of a recently proposed theory for IG wave turbulence, we demonstrate that baroclinic IG waves are typically highly nonlinear. For a number of mid- and high-latitude regions, the internal Rossby radius and the wave nonlinearity are estimated from T/P data and shown to agree with expected values. The degree of the wave nonlinearity is of great practical interest. In particular, it tells us about the intensity of internal wave breaking. Furthermore, estimating the velocity of baroclinic RW we derive additional information on the upper layer stratification. These experiments point to the feasibility of using observed SSH field statistics (such F(k) and W()) to monitor properties of and dynamical processes in the upper mixed layer of the ocean.

Satellite Altimeter↗

Method for beam hardening correction in quantitative computed X-ray tomography

Each voxel is assumed to contain exactly two distinct materials, with the volume fraction of each material being iteratively calculated. According to the method, the spectrum of the X-ray beam must be known, and the attenuation spectra of the materials in the object must be known, and be monotonically decreasing with increasing X-ray photon energy. Then, a volume fraction is estimated for the voxel, and the spectrum is iteratively calculated.

Yan, Chye Hwang↗

Applications of Computed Tomography to Evaluate Cellular Solid Interfaces

The major morphological features - foam cells, voids, knit lines, and the bondline interface were evaluated. The features identified by micro-CT correlate well to those observed by SEM. 3D reconstructions yielded volumetric dimensions for large voids (max ~ 30 mm). Internal voids and groupings of smaller cells at the bondline are concluded to be the cause of the indications noted during the NDE prescreening process.

Maisano, Josephine↗

Contrast enhanced spectroscopic optical coherence tomography

A method of forming an image of a sample includes performing SOCT on a sample. The sample may include a contrast agent, which may include an absorbing agent and/or a scattering agent. A method of forming an image of tissue may include selecting a contrast agent, delivering the contrast agent to the tissue, acquiring SOCT data from the tissue, and converting the SOCT data into an image. The contributions to the SOCT data of an absorbing agent and a scattering agent in a sample may be quantified separately.

Boppart, Stephen A.↗

Improving Bone-Health Monitoring in Astronauts: Recommended Use of Quantitative Computed Tomography [QCT] for Clinical and Operational Decisions by NASA

DXA measurement of areal bone mineral density [aBMD,g/cm2] is required by NASA for assessing skeletal integrity in astronauts. Due to the abundance of population-based data that correlate hip and spine BMDs to fragility fractures, BMD is widely applied as a predictor of fractures in the general aging population. In contrast, QCT is primarily a research technology that measures three-dimensional , volumetric BMD (vBMD,mg/cm3) of bone and is therefore capable of differentiating between cortical and trabecular components. Additionally, when combined with Finite Element Modeling [FEM], a computational tool, QCT data can be used to estimate the whole bone strength of the hip [FE strength] for a specific load vector. A recent report demonstrated that aBMD failed to correlate with incurred changes in FE strength (for fall and stance loading) by astronauts over typical 180-day ISS (International Space Station) missions. While there are no current guidelines for using QCT data in clinical practice, QCT increases the understanding of how bone structure and mineral content are affected by spaceflight and recovery on Earth. In order to understand/promote/consider the use of QCT, NASA convened a panel of clinicians specializing in osteoporosis. After reviewing the available, albeit limited, medical and research information from long-duration astronauts (e.g., data from DXA, QCT, FEM, biochemistry analyses, medical records and in-flight exercise performance) the panelists were charged with recommending how current and future research data and analyses could inform clinical and operational decisions. The Panel recommended that clinical bone tests on astronauts should include QCT (hip and lumbar spine) for occupational risk surveillance and for the estimation of whole hip bone strength as derived by FEM. FE strength will provide an improved index that NASA could use to select astronauts of optimal bone health for extended duration missions, for repeat missions or for specific mission operations.

Sibonga, J. D.↗

Electrical Impedance Tomography Technology (EITT) Project

Development of a portable, lightweight device providing two-dimensional tomographic imaging of the human body using impedance mapping. This technology can be developed to evaluate health risks and provide appropriate medical care on the ISS, during space travel and on the ground.

Technology Portfolio System↗

Measurement of Acute Changes in Choroid Thickness in Healthy Eyes During Posture Change Using Optical Coherence Tomography

The Visual Impairment and Intracranial Pressure (VIIP) syndrome affects 60% of astronauts returning from long-duration missions and is characterized by structural and functional changes of the eye (3). Upon entry into weightlessness, approximately two liters of fluid translocates from the lower body to the thorax and cephalad regions, potentially contributing to elevated intracranial and intraocular pressures. The choroid is the vasculature that supplies blood flow to the posterior part of the retina and has limited autoregulation. As a consequence these vessels may engorge during a cephalad fluid shift, contributing to structural changes in the retina. The purpose of this experiment was to quantify changes in choroid thickness during a fluid shift. In order to fulfill this objective, it was also necessary to improve the measurement technique for assessing choroid thickness.

Ferguson, Connor R.↗

Operational Transition from the First-Generation Heidelberg Spectralis Optical Coherence Tomography [OCT("OCT1")] to the Second-Generation Heidelberg Spectralis OCT("OCT2")

The Heidelberg Spectralis "OCT2", which recently became commercially available, is going to be implemented at the Johnson Space Center Flight Medicine Clinic and on board the International Space Station. Due to the increased scan rate of the "OCT2", this upgrade will allow for significant reduction in valuable crew testing time and also allow for additional capabilities, like OCT Angiography and Multi-Color Fundus Imaging. Due to the custom scans used to monitor Space Flight-Associated Neuro-ocular Syndrome (SANS) in our crewmembers, an evaluation to assess the impacts of transitioning from "OCT1" to "OCT2" was performed. An engineering assessment (N=1) was performed to identify any potential impacts of maintaining an "OCT1" on board ISS while implementing an "OCT2" in the JSC Clinic. "OCT2" implementation will lag JSC FMC clinical implementation due to the flight certification/manifestation process. The clinical assessment was performed (n=12) to identify any impacts due to the replacement of the "OCT1" with the "OCT2" to the longitudinal OCT data across a crewmember's mission/lifetime. The qualitative results from the engineering and clinical evaluation will be reported, as well as the quantitative assessment of the clinical variables

Mason, S.↗