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At least 1,045 records · Page 58

Preformed template fluctuations promote fibril formation: Insights from lattice and all-atom models

Fibril formation resulting from protein misfolding and aggregation is a hallmark of several neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases. Despite the fact that the fibril formation process is very slow and thus poses a significant challenge for theoretical and experimental studies, a number of alternative pictures of molecular mechanisms of amyloid fibril formation have been recently proposed. What seems to be common for the majority of the proposed models is that fibril elongation involves the formation of pre-nucleus seeds prior to the creation of a critical nucleus. Once the size of the pre-nucleus seed reaches the critical nucleus size, its thermal fluctuations are expected to be small and the resulting nucleus provides a template for sequential (one-by-one) accommodation of added monomers. The effect of template fluctuations on fibril formation rates has not been explored either experimentally or theoretically so far. In this paper, we make the first attempt at solving this problem by two sets of simulations. To mimic small template fluctuations, in one set, monomers of the preformed template are kept fixed, while in the other set they are allowed to fluctuate. The kinetics of addition of a new peptide onto the template is explored using all-atom simulations with explicit water and the GROMOS96 43a1 force field and simple lattice models. Our result demonstrates that preformed template fluctuations can modulate protein aggregation rates and pathways. The association of a nascent monomer with the template obeys the kinetics partitioning mechanism where the intermediate state occurs in a fraction of routes to the protofibril. It was shown that template immobility greatly increases the time of incorporating a new peptide into the preformed template compared to the fluctuating template case. This observation has also been confirmed by simulation using lattice models and may be invoked to understand the role of template fluctuations in slowing down fibril elongation in vivo.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

On the interplay between relaxation, defect formation, and atomic Sn distribution in Ge{sub (1−x)}Sn{sub (x)} unraveled with atom probe tomography

Ge{sub (1−x)}Sn{sub (x)} has received a lot of interest for opto-electronic applications and for strain engineering in advanced complementary-metal-oxide-semiconductor technology, because it enables engineering of the band gap and inducing strain in the alloy. To target a reliable technology for mass application in microelectronic devices, the physical problem to be addressed is to unravel the complex relationship between strain relaxation (as induced by the growth of large layer thicknesses or a thermal anneal) and defect formation, and/or stable Sn-cluster formation. In this paper, we study the onset of Sn-cluster formation and its link to strain relaxation using Atom Probe Tomography (APT). To this end, we also propose a modification of the core-linkage [Stephenson et al., Microsc. Microanal. 13, 448 (2007)] cluster analysis method, to overcome the challenges of limited detection efficiency and lateral resolution of APT, and the quantitative assessment for very small clusters (<40 atoms) embedded in a random distribution of Sn-atoms. We concluded that the main relaxation mechanism for these layers is defect generation (misfit dislocations, threading dislocations, etc.), irrespective of the cause (thickness of layer or thermal anneal) of relaxation and is independent of the cluster formation. The low thermodynamic solubility limit of Sn in Ge seems to be the driving force for Sn-cluster formation. Finally, we also discuss the spatial distribution of Sn in clusters and relate them to the theoretically predicted stable Sn clusters [Ventura et al., Phys. Rev. B 79, 155202 (2009)].

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Transient β-hairpin formation in α-synuclein monomer revealed by coarse-grained molecular dynamics simulation

Parkinson’s disease, originating from the intrinsically disordered peptide α-synuclein, is a common neurodegenerative disorder that affects more than 5% of the population above age 85. It remains unclear how α-synuclein monomers undergo conformational changes leading to aggregation and formation of fibrils characteristic for the disease. In the present study, we perform molecular dynamics simulations (over 180 μs in aggregated time) using a hybrid-resolution model, Proteins with Atomic details in Coarse-grained Environment (PACE), to characterize in atomic detail structural ensembles of wild type and mutant monomeric α-synuclein in aqueous solution. The simulations reproduce structural properties of α-synuclein characterized in experiments, such as secondary structure content, long-range contacts, chemical shifts, and {sup 3}J(H{sub N}H{sub C{sub α}})-coupling constants. Most notably, the simulations reveal that a short fragment encompassing region 38-53, adjacent to the non-amyloid-β component region, exhibits a high probability of forming a β-hairpin; this fragment, when isolated from the remainder of α-synuclein, fluctuates frequently into its β-hairpin conformation. Two disease-prone mutations, namely, A30P and A53T, significantly accelerate the formation of a β-hairpin in the stated fragment. We conclude that the formation of a β-hairpin in region 38-53 is a key event during α-synuclein aggregation. We predict further that the G47V mutation impedes the formation of a turn in the β-hairpin and slows down β-hairpin formation, thereby retarding α-synuclein aggregation.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Experimental explanation of the formation mechanism of surface mound-structures by femtosecond laser on polycrystalline Ni{sub 60}Nb{sub 40}

Femtosecond laser surface processing (FLSP) is an emerging technique for creating functionalized surfaces with specialized properties, such as broadband optical absorption or superhydrophobicity/superhydrophilicity. It has been demonstrated in the past that FLSP can be used to form two distinct classes of mound-like, self-organized micro/nanostructures on the surfaces of various metals. Here, the formation mechanisms of below surface growth (BSG) and above surface growth (ASG) mounds on polycrystalline Ni{sub 60}Nb{sub 40} are studied. Cross-sectional imaging of these mounds by focused ion beam milling and subsequent scanning electron microscopy revealed evidence of the unique formation processes for each class of microstructure. BSG-mound formation during FLSP did not alter the microstructure of the base material, indicating preferential valley ablation as the primary formation mechanism. For ASG-mounds, the microstructure at the peaks of the mounds was clearly different from the base material. Transmission electron microscopy revealed that hydrodynamic melting of the surface occurred during FLSP under ASG-mound forming conditions. Thus, there is a clear difference in the formation mechanisms of ASG- and BSG-mounds during FLSP.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

In situ multimodal imaging for nanoscale visualization of tribofilm formation

A third of the energy from fuel combustion in passenger car gasoline engines is lost due to friction. Carefully designed engine lubricants can recover some of these losses by reducing friction and wear by forming a nanometer-scale chemico-physico tribofilm between surfaces. Accordingly, attention has focused on developing oil formulations that form low-friction tribofilms. However, analyses of resultant tribofilms are typically conducted after tribo-tests with conventional characterization tools and do not offer insights into tribofilm formation and evolution, precluding information critical to tuning tribofilm properties. In this work, we developed a unique multimodal methodology based on Atomic Force Microscopy (AFM) with local probe heating for in situ tribological studies that activates friction modifiers and simultaneously captures the evolution of friction and surface roughness, with nanometer resolution. As a platform to demonstrate the ability of this methodology to visualize dynamics of tribofilm formation in situ, we apply it to molybdenum-based friction modifiers to distinguish key factors in their functionality and correlate nanoscale AFM and Friction Force Microscopy data to bench tribo-tests used in the industry. To decode the formation mechanisms observed in situ and underlying chemistry of tribofilms, we performed ab initio Molecular Dynamics (AIMD) simulations at comparable conditions. AIMD simulations confirmed both nanoscale and bench tribo-test results and showed deviations in molecular organization in tribofilms that are formed from different molybdenum-based friction modifiers that corroborates with surface functionality. With this innovative methodology, we demonstrate proof-of-principle in situ formation of molybdenum-based tribofilms directly on steel surfaces that could be applied generally to studying tribofilm formation.

36 MATERIALS SCIENCE↗

Hole formation effect on surface morphological response of plasma-facing tungsten

We report simulation results on the effect of helium (He) bubble bursting-mediated surface hole formation on the surface morphological response of tungsten plasma-facing components (PFCs) in nuclear fusion devices. Our analysis is based on an atomistically informed, continuum-scale model, which is capable of accessing the spatiotemporal scales relevant to the fuzz nanostructure formation process on the surface of PFC tungsten. Our simulations account, in an empirical fashion, for two types of subsurface bubble dynamical phenomena in the nanobubble region of PFC tungsten during He plasma irradiation, involving bubble bursting and surface crater formation. We demonstrate that the hole formation effect on the PFC tungsten surface accelerates the growth rate of nanotendrils and the onset of fuzz formation. As a result, the predicted incubation time for surface nanotendril growth is shortened, in agreement with experimental data of incubation fluence at comparable plasma exposure conditions. We also explore systematically the dependence of the PFC surface morphological response on the areal density of holes introduced at regular time intervals onto the He-implanted tungsten surface, a parameter in our analysis that serves as a proxy for the rate of He bubble bursting. More importantly, our simulations capture fine surface features in the PFC tungsten surface morphology and predict that the average spacing between nanotendrils is on the order of 100 nm, consistent with the experimental findings.

Chen, Chao-Shou (ORCID:0000000307910042)↗

Experimental observations of detached bow shock formation in the interaction of a laser-produced plasma with a magnetized obstacle

The magnetic field produced by planets with active dynamos, like the Earth, can exert sufficient pressure to oppose supersonic stellar wind plasmas, leading to the formation of a standing bow shock upstream of the magnetopause, or pressure-balance surface. Scaled laboratory experiments studying the interaction of an inflowing solar wind analog with a strong, external magnetic field are a promising new way to study magnetospheric physics and to complement existing models, although reaching regimes favorable for magnetized shock formation is experimentally challenging. This paper presents experimental evidence of the formation of a magnetized bow shock in the interaction of a supersonic, super-Alfvenic plasma with a strongly magnetized obstacle at the OMEGA laser facility. The solar wind analog is generated by the collision and subsequent expansion of two counterpropagating, laser-driven plasma plumes. The magnetized obstacle is a thin wire, driven with strong electrical currents. Hydrodynamic simulations using the FLASH code predict that the colliding plasma source meets the criteria for bow shock formation. Spatially resolved, optical Thomson scattering measures the electron number density, and optical emission lines provide a measurement of the plasma temperature, from which we infer the presence of a fast magnetosonic shock far upstream of the obstacle. Proton images provide a measure of large-scale features in the magnetic field topology, and reconstructed path-integrated magnetic field maps from these images suggest the formation of a bow shock upstream of the wire and as a transient magnetopause. Finally, we compare features in the reconstructed fields to two-dimensional MHD simulations of the system.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Computationally guided experimental validation of divacancy defect formation in 4H-SiC

Recent research into solid-state qubits for quantum information science has focused on optically addressable spin defects such as the negatively charged nitrogen-vacancy center in diamond and the neutrally charged divacancy (VV) in 4H-SiC as scalable quantum sensors and networking qubits. Within this context, direct investigations of the structural origin and defect formation dynamics of a sub-set of the VV center in 4H-SiC remain lacking. Here, we take a systematic experimental approach guided by predictions from first-principles simulations to gain a thorough mechanistic understanding of the VV defect formation and control in 4H-SiC. We study the effect of annealing time and temperature on VV formation in high-purity semi-insulating 4H-SiC samples following electron irradiation. Three different temperatures (1123, 1273, and 1473 K) and annealing duration (from 0.5 to 72 h) are chosen to explore VV formation in different regions. We find that samples annealed at 1273 K give the highest VV-related photoluminescence (PL) intensities, in agreement with the prediction from first-principles calculations. Furthermore, the logarithmic dependence of VV-related PL intensities on the annealing duration at 1273 K indicates that 1273 K provides sufficient thermal energy for silicon vacancy migration but not for VV migration. Together, these results suggest that efficient VV formation occurs above the V Si migration temperature and below the VV migration threshold.

74 ATOMIC AND MOLECULAR PHYSICS↗

Formation of HONO from the NH 3 -promoted hydrolysis of NO 2 dimers in the atmosphere

One challenging issue in atmospheric chemistry is identifying the source of nitrous acid (HONO), which is believed to be a primary source of atmospheric “detergent” OH radicals. Herein, we show a reaction route for the formation of HONO species from the NH 3 -promoted hydrolysis of a NO 2 dimer (ONONO 2 ), which entails a low free-energy barrier of 0.5 kcal/mol at room temperature. Our systematic study of HONO formation based on NH 3 + ONONO 2 + n H 2 O and water droplet systems with the metadynamics simulation method and a reaction pathway searching method reveals two distinct mechanisms: ( i ) In monohydrates ( n = 1), tetrahydrates ( n = 4), and water droplets, only one water molecule is directly involved in the reaction (denoted the single-water mechanism); and ( ii ) the splitting of two neighboring water molecules is seen in the dihydrates ( n = 2) and trihydrates ( n = 3) (denoted the dual-water mechanism). A comparison of the computed free-energy surface for NH 3 -free and NH 3 -containing systems indicates that gaseous NH 3 can markedly lower the free-energy barrier to HONO formation while stabilizing the product state, producing a more exergonic reaction, in contrast to the endergonic reaction for the NH 3 -free system. More importantly, the water droplet reduces the free-energy barrier for HONO formation to 0.5 kcal/mol, which is negligible at room temperature. We show that the entropic contribution is important in the mechanism by which NH 3 promotes HONO formation. Furthermore, this study provides insight into the importance of fundamental HONO chemistry and its broader implication to aerosol and cloud processing chemistry at the air–water interface.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Are turbulence effects on droplet collision–coalescence a key to understanding observed rain formation in clouds?

Rain formation is a critical factor governing the lifecycle and radiative forcing of clouds and therefore it is a key element of weather and climate. Cloud microphysics–turbulence interactions occur across a wide range of scales and are challenging to represent in atmospheric models with limited resolution. Based on past experiments and idealized numerical simulations, it has been postulated that cloud turbulence accelerates rain formation by enhancing drop collision–coalescence. We provide substantial evidence for significant impacts of turbulence on the evolution of cloud droplet size distributions and rain formation by comparing high-resolution observations of cumulus congestus clouds with state-of-the-art large-eddy simulations coupled with a Lagrangian particle-based microphysics scheme. Turbulent coalescence must be included in the model to accurately represent the observed drop size distributions, especially for drizzle drop sizes at lower heights in the cloud. Turbulence causes earlier rain formation and greater rain accumulation compared to simulations with gravitational coalescence only. The observed rain size distribution tail just above cloud base follows a power law scaling that deviates from theoretical scalings considering either a purely gravitation collision kernel or a turbulent kernel neglecting droplet inertial effects, providing additional evidence for turbulent coalescence in clouds. In contrast, large aerosols acting as cloud condensation nuclei (“giant CCN”) do not significantly impact rain formation owing to their long timescale to reach equilibrium wet size relative to the lifetime of rising cumulus thermals. Overall, turbulent drop coalescence exerts a dominant influence on rain initiation in warm cumulus clouds, with limited impacts of giant CCN.

54 ENVIRONMENTAL SCIENCES↗

Multicolor photometry of the merging galaxy cluster A2319: Dynamics and star formation properties

Asymmetric X-ray emission and a powerful cluster-scale radio halo indicate that A2319 is a merging cluster of galaxies. This paper presents our multicolor photometry for A2319 with 15 optical intermediate filters in the Beijing-Arizona-Taiwan-Connecticut (BATC) system. There are 142 galaxies with known spectroscopic redshifts within the viewing field of 58' × 58' centered on this rich cluster, including 128 member galaxies (called sample I). A large velocity dispersion in the rest frame, 1622{sub −70}{sup +91} km s{sup –1}, suggests merger dynamics in A2319. The contour map of projected density and localized velocity structure confirm the so-called A2319B substructure, at ∼10' northwest to the main concentration A2319A. The spectral energy distributions (SEDs) of more than 30,000 sources are obtained in our BATC photometry down to V ∼ 20 mag. A u-band (∼3551 Å) image with better seeing and spatial resolution, obtained with the Bok 2.3 m telescope at Kitt Peak, is taken to make star-galaxy separation and distinguish the overlapping contamination in the BATC aperture photometry. With color-color diagrams and photometric redshift technique, 233 galaxies brighter than h {sub BATC} = 19.0 are newly selected as member candidates after an exclusion of false candidates with contaminated BATC SEDs by eyeball-checking the u-band Bok image. The early-type galaxies are found to follow a tight color-magnitude correlation. Based on sample I and the enlarged sample of member galaxies (called sample II), subcluster A2319B is confirmed. The star formation properties of cluster galaxies are derived with the evolutionary synthesis model, PEGASE, assuming a Salpeter initial mass function and an exponentially decreasing star formation rate (SFR). A strong environmental effect on star formation histories is found in the manner that galaxies in the sparse regions have various star formation histories, while galaxies in the dense regions are found to have shorter SFR time scales, older stellar ages, and higher interstellar medium metallicities. For the merging cluster A2319, local surface density is a better environmental indicator rather than the cluster-centric distance. Compared with the well-relaxed cluster A2589, a higher fraction of star-forming galaxies is found in A2319, indicating that the galaxy-scale turbulence stimulated by the subcluster merger might have played a role in triggering the star formation activity.

79 ASTRONOMY AND ASTROPHYSICS↗

STAR FORMATION ACROSS THE W3 COMPLEX

We present a multi-wavelength analysis of the history of star formation in the W3 complex. Using deep, near-infrared ground-based images combined with images obtained with Spitzer and Chandra observatories, we identified and classified young embedded sources. We identified the principal clusters in the complex and determined their structure and extension. We constructed extinction-limited samples for five principal clusters and constructed K-band luminosity functions that we compare with those of artificial clusters with varying ages. This analysis provided mean ages and possible age spreads for the clusters. We found that IC 1795, the centermost cluster of the complex, still hosts a large fraction of young sources with circumstellar disks. This indicates that star formation was active in IC 1795 as recently as 2 Myr ago, simultaneous to the star-forming activity in the flanking embedded clusters, W3-Main and W3(OH). A comparison with carbon monoxide emission maps indicates strong velocity gradients in the gas clumps hosting W3-Main and W3(OH) and shows small receding clumps of gas at IC 1795, suggestive of rapid gas removal (faster than the T Tauri timescale) in the cluster-forming regions. We discuss one possible scenario for the progression of cluster formation in the W3 complex. We propose that early processes of gas collapse in the main structure of the complex could have defined the progression of cluster formation across the complex with relatively small age differences from one group to another. However, triggering effects could act as catalysts for enhanced efficiency of formation at a local level, in agreement with previous studies.

79 ASTRONOMY AND ASTROPHYSICS↗

THE PROGRESSION OF STAR FORMATION IN THE ROSETTE MOLECULAR CLOUD

Using Spitzer Space Telescope and Chandra X-Ray Observatory data, we identify young stellar objects (YSOs) in the Rosette Molecular Cloud (RMC). By being able to select cluster members and classify them into YSO types, we are able to track the progression of star formation locally within the cluster environments and globally within the cloud. We employ the nearest neighbor method analysis to explore the density structure of the clusters and YSO ratio mapping to study age progressions in the cloud. We find a relationship between the YSO ratios and extinction that suggests star formation occurs preferentially in the densest parts of the cloud and that the column density of gas rapidly decreases as the region evolves. This suggests rapid removal of gas may account for the low star formation efficiencies observed in molecular clouds. We find that the overall age spread across the RMC is small. Our analysis suggests that star formation started throughout the complex around the same time. Age gradients in the cloud appear to be localized and any effect the H II region has on the star formation history is secondary to that of the primordial collapse of the cloud.

79 ASTRONOMY AND ASTROPHYSICS↗

THE AVERAGE STAR FORMATION HISTORIES OF GALAXIES IN DARK MATTER HALOS FROM z = 0-8

We present a robust method to constrain average galaxy star formation rates (SFRs), star formation histories (SFHs), and the intracluster light (ICL) as a function of halo mass. Our results are consistent with observed galaxy stellar mass functions, specific star formation rates (SSFRs), and cosmic star formation rates (CSFRs) from z = 0 to z = 8. We consider the effects of a wide range of uncertainties on our results, including those affecting stellar masses, SFRs, and the halo mass function at the heart of our analysis. As they are relevant to our method, we also present new calibrations of the dark matter halo mass function, halo mass accretion histories, and halo-subhalo merger rates out to z = 8. We also provide new compilations of CSFRs and SSFRs; more recent measurements are now consistent with the buildup of the cosmic stellar mass density at all redshifts. Implications of our work include: halos near 10{sup 12} M{sub Sun} are the most efficient at forming stars at all redshifts, the baryon conversion efficiency of massive halos drops markedly after z {approx} 2.5 (consistent with theories of cold-mode accretion), the ICL for massive galaxies is expected to be significant out to at least z {approx} 1-1.5, and dwarf galaxies at low redshifts have higher stellar mass to halo mass ratios than previous expectations and form later than in most theoretical models. Finally, we provide new fitting formulae for SFHs that are more accurate than the standard declining tau model. Our approach places a wide variety of observations relating to the SFH of galaxies into a self-consistent framework based on the modern understanding of structure formation in {Lambda}CDM. Constraints on the stellar mass-halo mass relationship and SFRs are available for download online.

79 ASTRONOMY AND ASTROPHYSICS↗

THE IMACS CLUSTER BUILDING SURVEY. III. THE STAR FORMATION HISTORIES OF FIELD GALAXIES

Using data from the IMACS Cluster Building Survey and from nearby galaxy surveys, we examine the evolution of the rate of star formation in field galaxies from z = 0.60 to the present. Fitting the luminosity function to a standard Schechter form, we find a rapid evolution of M{sub B}{sup *} consistent with that found in other deep surveys; at the present epoch M{sub B}{sup *} is evolving at the rate of 0.38 Gyr{sup -1}, several times faster than the predictions of simple models for the evolution of old, coeval galaxies. The evolution of the distribution of specific star formation rates (SSFRs) is also too rapid to explain by such models. We demonstrate that starbursts cannot, even in principle, explain the evolution of the SSFR distribution. However, the rapid evolution of both M{sub B}{sup *} and the SSFR distribution can be explained if some fraction of galaxies have star formation rates characterized by both short rise and fall times and by an epoch of peak star formation more recent than the majority of galaxies. Although galaxies of every stellar mass up to 1.4 Multiplication-Sign 10{sup 11} M{sub Sun} show a range of epochs of peak star formation, the fraction of ''younger'' galaxies falls from about 40% at a mass of 4 Multiplication-Sign 10{sup 10} M{sub Sun} to zero at a mass of 1.4 Multiplication-Sign 10{sup 11} M{sub Sun }. The incidence of younger galaxies appears to be insensitive to the density of the local environment; but does depend on group membership: relatively isolated galaxies are much more likely to be young than are group members.

79 ASTRONOMY AND ASTROPHYSICS↗

THE IMACS CLUSTER BUILDING SURVEY. IV. THE LOG-NORMAL STAR FORMATION HISTORY OF GALAXIES

We present here a simple model for the star formation history (SFH) of galaxies that is successful in describing both the star formation rate density (SFRD) over cosmic time, as well as the distribution of specific star formation rates (sSFRs) of galaxies at the current epoch, and the evolution of this quantity in galaxy populations to a redshift of z = 1. We show first that the cosmic SFRD is remarkably well described by a simple log-normal in time. We next postulate that this functional form for the ensemble is also a reasonable description for the SFHs of individual galaxies. Using the measured sSFRs for galaxies at z {approx} 0 from Paper III in this series, we then construct a realization of a universe populated by such galaxies in which the parameters of the log-normal SFH of each galaxy are adjusted to match the sSFRs at z {approx} 0 as well as fitting, in ensemble, the cosmic SFRD from z = 0 to z = 8. This model predicts, with striking fidelity, the distribution of sSFRs in mass-limited galaxy samples to z = 1; this match is not achieved by other models with a different functional form for the SFHs of individual galaxies, but with the same number of degrees of freedom, suggesting that the log-normal form is well matched to the likely actual histories of individual galaxies. We also impose the sSFR versus mass distributions at higher redshifts from Paper III as constraints on the model, and show that, as previously suggested, some galaxies in the field, particularly low mass galaxies, are quite young at intermediate redshifts. As emphasized in Paper III, starbursts are insufficient to explain the enhanced sSFRs in intermediate redshift galaxies; we show here that a model using only smoothly varying log-normal SFHs for galaxies, which allows for some fraction of the population to have peak star formation at late times, does however fully explain the observations. Finally, we show that this model, constrained in detail only at redshifts z < 1, also produces the main sequence of star-formation observed at 1.5 < z < 2.5, again suggesting that the log-normal SFHs are a close approximation to the actual histories of typical galaxies.

79 ASTRONOMY AND ASTROPHYSICS↗

THE DEPENDENCE OF STAR FORMATION EFFICIENCY ON GAS SURFACE DENSITY

Studies by Lada et al. and Heiderman et al. have suggested that star formation mostly occurs above a threshold in gas surface density {Sigma} of {Sigma}{sub c} {approx} 120 M{sub Sun} pc{sup -2} (A{sub K} {approx} 0.8). Heiderman et al. infer a threshold by combining low-mass star-forming regions, which show a steep increase in the star formation rate per unit area {Sigma}{sub SFR} with increasing {Sigma}, and massive cores forming luminous stars which show a linear relation. We argue that these observations do not require a particular density threshold. The steep dependence of {Sigma}{sub SFR}, approaching unity at protostellar core densities, is a natural result of the increasing importance of self-gravity at high densities along with the corresponding decrease in evolutionary timescales. The linear behavior of {Sigma}{sub SFR} versus {Sigma} in massive cores is consistent with probing dense gas in gravitational collapse, forming stars at a characteristic free-fall timescale given by the use of a particular molecular tracer. The low-mass and high-mass regions show different correlations between gas surface density and the area A spanned at that density, with A {approx} {Sigma}{sup -3} for low-mass regions and A {approx} {Sigma}{sup -1} for the massive cores; this difference, along with the use of differing techniques to measure gas surface density and star formation, suggests that connecting the low-mass regions with massive cores is problematic. We show that the approximately linear relationship between dense gas mass and stellar mass used by Lada et al. similarly does not demand a particular threshold for star formation and requires continuing formation of dense gas. Our results are consistent with molecular clouds forming by galactic hydrodynamic flows with subsequent gravitational collapse.

79 ASTRONOMY AND ASTROPHYSICS↗

Radio constraints on heavily obscured star formation within dark gamma-ray burst host galaxies

Highly dust-obscured starbursting galaxies (submillimeter galaxies and their ilk) represent the most extreme sites of star formation in the distant universe and contribute significantly to overall cosmic star formation beyond z > 1.5. Some stars formed in these environments may also explode as gamma-ray bursts (GRBs) and contribute to the population of 'dark' bursts. Here we present Very Large Array wideband radio-continuum observations of 15 heavily dust-obscured Swift GRBs to search for radio synchrotron emission associated with intense star formation in their host galaxies. Most of these targets (11) are not detected. Of the remaining four objects, one detection is marginal, and for two others we cannot yet rule out the contribution of a long-lived radio afterglow. The final detection is secure, but indicates a star formation rate (SFR) roughly consistent with the dust-corrected UV-inferred value. Most galaxies hosting obscured GRBs are therefore not forming stars at extreme rates, and the amount of optical extinction seen along a GRB afterglow sightline does not clearly correlate with the likelihood that the host has a sufficiently high SFR to be radio-detectable. While some submillimeter galaxies do readily produce GRBs, these GRBs are often not heavily obscured—suggesting that the outer (modestly obscured) parts of these galaxies overproduce GRBs and the inner (heavily obscured) parts underproduce GRBs relative to their respective contributions to star formation, hinting at strong chemical or initial mass function gradients within these systems.

79 ASTRONOMY AND ASTROPHYSICS↗