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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 1,045 records · Page 58
All sourcesNASA NTRSDOE OSTI
NASA NTRS2018

Evaluation of Usability and Workload Associated with Paper Strips as Compared to Virtual Flight Strips Used for Ramp Operations

This paper describes a study comparing the use of paper strips with virtual flight strips depicted on a new user interface, the Ramp Traffic Console (RTC), designed for use by ramp controllers to be used in place of paper strips. A Human-In-the-Loop (HITL) experiment was performed as the fifth in a series of six HITL simulation studies designed to evaluate a pushback Decision Support Tool (DST) concept for Charlotte Douglas International Airport (CLT). Workload and usability were assessed in post-run and post-study questionnaires. In the RTC virtual flight strip condition, post-run questionnaire results show lower workload ratings across all aspects of workload; additionally a trend is found toward increased usability ratings. Post-study questionnaire results indicate a preference for RTC over paper strips. Additional research is suggested with more training runs and a greater number of participants to increase statistical power. It is also suggested that this new technology be re-evaluated as a part of the ATD-2 (Airspace Technology Demonstration 2) field testing activities.

Human Factors↗
NASA NTRS1985

Study of turbine bypass remote augmentor lift system for V/STOL aircraft

The airframe design and engine/aircraft integration were emphasized in a NASA comparative study of turbofan and turbine bypass engine (TBE) with remote augmentor lift systems (RALS) for supersonic V/STOL aircraft. Functional features of the TBE are reviewed, noting the enhanced cycle efficiency and reduced afterbody drag compared to the turbojets. The present studies examied performance levels for aircraft with fleet defense and secondary anti-surface warfare roles, carrying AMRAAM and AIM missiles. TBE engine cycles were configured for hover and up-and-away flight from deck launch, and all tests were done from a conceptual design viewpoint. The results indicate that the TBE-RALS is superior to turbofan-RALS aircraft in both gross take-off weight and life cycle cost.

Sheridan, A. E.↗
DOE OSTI2017

The structure-activity relationship of ginsenosides on hypoxia-reoxygenation induced apoptosis of cardiomyocytes

Highlights: • Ginsenosides have cardioprotective effects on hypoxia and reoxygenation-induced damage. • There is a structure-activity relationship regarding ginsenosides' inhibition of apoptosis. • AMPK could be an important mediator for ginsenosides' cardioprotection against hypoxic injury. Ginsenosides have been studied extensively in recent years due to their therapeutic effects in cardiovascular diseases. While most studies examined the different ginsenosides individually, few studies compare the therapeutic effects among the different types. This study examined how effective protopanaxadiol, protopanaxatriol ginsenosides Rh2, Rg3, Rh1, and Rg2 of the ginsenoside family are in protecting H9c2 cardiomyocytes from damage caused by hypoxia/reoxygenation. In the current study, a model of myocardial ischemia and reperfusion was induced in H9c2 cardiomyocytes by oxygen deprivation via a hypoxia chamber followed by reoxygenation. Our data show that structures similar to that of protopanaxadiol, which lacked the hydroxide group at C6, were more effective in lowering apoptosis than structures similar to protopanaxatriol with a hydroxide group at C6. As the compounds increased in size and complexity, the cardioprotective effects diminished. In addition, the S enantiomer proved to be more effective in cardioprotection than the R enantiomer. Furthermore, the immunoblotting analysis demonstrated that ginsenosides activate AMPK but suppress JNK signaling pathways during hypoxia/reoxygenation. Thus, ginsenosides treatment attenuated hypoxia/reoxygenation-induced apoptosis via modulating cardioprotective AMPK and inflammation-related JNK signaling pathways.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2023

Development and demonstration of a rolling ball viscometer for molten salts with near-minimum liquidus NaCl–KCl

The thermophysical characterization of molten chloride and fluoride salts is a key interest for the development of advanced molten salt nuclear reactors. Viscosity is one thermophysical property of interest; a high-accuracy understanding of this property is necessary for modeling the thermal energy transfer and mass flow rate for a given molten salt system. Only a few methods have consistently been used to measure the viscosity of molten chloride and fluoride salt systems, and large discrepancies have been observed in the literature between independent studies of nearly identical salt systems. As such, exploration of novel measurement methods or implementations may allow for further validation, improved measurement accuracy, and overall improved understanding about optimal approaches for measuring molten salt viscosity. Here, in this study, a novel implementation of the rolling ball viscometry method was used to measure the viscosity of a 44/56 mol % mixture of NaCl–KCl within a temperature range of 714–838 °C, with the intent to demonstrate the feasibility of this technique for molten salt viscosity measurement cross-validation. The purity of this salt was confirmed through laser-induced breakdown spectroscopy. Measured viscosities were approximately 1.3–1.0 cP within this temperature range, and the overall uncertainty was 10.8%, which was determined through Gaussian error propagation. The results agree reasonably well with measured viscosities of similar NaCl–KCl mixtures in the literature (within 2%–20% depending on the temperature and study), although the experimental error in some of these comparative studies may be significant.

47 OTHER INSTRUMENTATION↗
DOE OSTI2022

Modeling and experimental validation of dynamical effects in Bragg coherent x-ray diffractive imaging of finite crystals

Bragg coherent diffractive imaging (BCDI) is a noninvasive microscopy technique that can visualize the shape and internal lattice deviations of crystals with nanoscale spatial resolution and picometer deformation sensitivity. Its strain imaging capability relies on Fourier transform–based iterative phase retrieval algorithms, which are mostly developed under the kinematical approximation. Such approximation prohibits the application of BCDI on larger crystals, which are commonly seen in most emerging functional materials. Understanding the dynamical effect in BCDI, as well as developing a validated method for modeling BCDI at the dynamical diffraction limit, is crucial for applying BCDI to hierarchical systems that contain micron-sized crystals and grains. Thus we report a comparative study on the impact of dynamical diffraction effects by comparing the reconstruction results from two measurements of the same crystal. Forward simulation is implemented to show subtle changes of interference fringes in the diffraction pattern due to the dynamical diffraction, and is compared directly with the experimental data.

36 MATERIALS SCIENCE↗
DOE OSTI2015

Influence of Pressure on Physical Property of Ammonia Borane and its Re-hydrogenation

The project systematically studied the high pressure behavior of ammonia borane and its derivative lithium amidoborane. Phase transitions in these materials are investigated in the pressure range up to 20 GPa and temperature range from 80 K to 400K. A number of new phase transitions are discovered in this pressure and temperature range including a second order transformation at 5 GPa and a first order transformation at 12 GPa at room temperature, and four new transitions at high pressure and low temperatures. The Clapeyron slopes for both pressure-induce tetragonal (I4mm) phase to orthorhombic (Cmc21) phase and temperature-induce tetragonal (I4mm) phase to orthorhombic (Pmn21) phase are determined to be positive, indicating these phase transitions are exothermic. This result demonstrates that the high pressure orthorhombic phase of ammonia borane has lower enthalpy than that of tetragonal phase at ambient conditions. If we assume decomposition from the orthorhombic phase yields the same products as that from the tetragonal phase, the decomposition of the orthorhombic phase will be less exothermic. Therefore rehydrogenation from the decomposed product into the orthorhombic phase at high pressure may become easier. The project also studied the influences of nanoconfinement on the phase transitions. Comparative study using Raman spectroscopy indicates that the temperature induced I4mm to Pmn21 transition is suppressed from 217 K to 195 K when the sample is confined in SBA15 (7-9 nm pore size). When the pore size is reduced from 7-9 nm to 3-4 nm, this transition is totally suppressed in the temperature down to 80 K. A similar influence of the nanoconfiement on pressure induced phase transitions is also observed using Raman spectroscopy. The phase boundary between the I4mm phase and high pressure Cmc21 phase at ambient temperature shifts from 0.9 GPa to 0.5 GPa; and that between the Cmc21 phase and higher pressure P21 phase shifts from 10.2 GPa to 9.7 GPa.

08 HYDROGEN↗
DOE OSTI2014

Theoretical structural and vibrational study of 5-trifluoromethyluracil. A comparison with uracil

In the present work, a comparative study on the structural and vibrational properties of the 5-trifluoromethyluracil (TFMU) derivative with those corresponding to uracil in gas and aqueous solution phases was performed combining the available H{sup 1}-NMR, C{sup 13}-NMR, F{sup 19}-NMR and FTIR spectra with Density Functional Theory (DFT) calculations. Three stable conformers were theoretically determined in both media by using the hybrid B3LYP/6-31G* method. The solvent effects were simulated by means of the self-consistent reaction field (SCRF) method employing the integral equation formalism variant (IEFPCM). Complete assignments of the vibrational spectra in both phases were performed combining the internal coordinates analysis and the DFT calculations with the Scaled Quantum Mechanics Force Field (SQMFF) methodology. The atomic charges, bond orders, solvation energies, dipole moments, molecular electrostatic potentials and force constants parameters were calculated for the three conformers of TFMU in gas phase and aqueous solution.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗
DOE OSTI2020

Studies on magnetocaloric effect of Tb 2 Ni 0.90 Si 2.94 compound

A comparative study has been carried out on the magnetocaloric properties of as-cast and annealed Tb 2 Ni 0.90 Si 2.94 intermetallic compound. While the as-cast material exhibits ferromagnetic cluster-glass behaviour below 9.9 K coexisting with antiferromagnetic (AFM) interaction, the annealed system shows AFM ordering below 13.5 K and spin freezing occurs below 4 K. The compound exhibits moderate magnetocaloric performance with maximum isothermal entropy changes (–ΔS M ) 8.8 and 10.9 J kg –1 K –1 , relative cooling power (RCP) 306 and 365 J kg –1 , along with adiabatic temperature change (ΔT ad ) 5.5 and 8.15 K for 70 kOe magnetic field change in as-cast and annealed forms, respectively. The estimated magnetic entropy change is found to be larger for annealed sample in comparison to that of as-cast analogue. However, the full width at half maxima (FWHM) of –ΔS M (T) behaviour is larger in as-cast compound due to the presence of inherent structural disorder which reduces with thermal annealing. A positive isothermal entropy change (–ΔS M ) and adiabatic temperature change (ΔT ad ) is observed for the as-cast compound in the measured field and temperature region. In contrast, the annealed system exhibits inverse magnetocaloric effect in the low field and temperature region where AFM interactions dominate. Magnetocaloric effect (MCE) is used as a tool to establish a subtle correlation between the observed magnetocaloric effect and the reported magnetic properties of the system.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗
NASA NTRS2002

Comparing a Coevolutionary Genetic Algorithm for Multiobjective Optimization

We present results from a study comparing a recently developed coevolutionary genetic algorithm (CGA) against a set of evolutionary algorithms using a suite of multiobjective optimization benchmarks. The CGA embodies competitive coevolution and employs a simple, straightforward target population representation and fitness calculation based on developmental theory of learning. Because of these properties, setting up the additional population is trivial making implementation no more difficult than using a standard GA. Empirical results using a suite of two-objective test functions indicate that this CGA performs well at finding solutions on convex, nonconvex, discrete, and deceptive Pareto-optimal fronts, while giving respectable results on a nonuniform optimization. On a multimodal Pareto front, the CGA finds a solution that dominates solutions produced by eight other algorithms, yet the CGA has poor coverage across the Pareto front.

Lohn, Jason D.↗
NASA NTRS1989

Sparse matrix methods research using the CSM testbed software system

Research is described on sparse matrix techniques for the Computational Structural Mechanics (CSM) Testbed. The primary objective was to compare the performance of state-of-the-art techniques for solving sparse systems with those that are currently available in the CSM Testbed. Thus, one of the first tasks was to become familiar with the structure of the testbed, and to install some or all of the SPARSPAK package in the testbed. A suite of subroutines to extract from the data base the relevant structural and numerical information about the matrix equations was written, and all the demonstration problems distributed with the testbed were successfully solved. These codes were documented, and performance studies comparing the SPARSPAK technology to the methods currently in the testbed were completed. In addition, some preliminary studies were done comparing some recently developed out-of-core techniques with the performance of the testbed processor INV.

Chu, Eleanor↗
DOE OSTI2013

Minipig and beagle animal model genomes aid species selection in pharmaceutical discovery and development

Improving drug attrition remains a challenge in pharmaceutical discovery and development. A major cause of early attrition is the demonstration of safety signals which can negate any therapeutic index previously established. Safety attrition needs to be put in context of clinical translation (i.e. human relevance) and is negatively impacted by differences between animal models and human. In order to minimize such an impact, an earlier assessment of pharmacological target homology across animal model species will enhance understanding of the context of animal safety signals and aid species selection during later regulatory toxicology studies. Here we sequenced the genomes of the Sus scrofa Göttingen minipig and the Canis familiaris beagle, two widely used animal species in regulatory safety studies. Comparative analyses of these new genomes with other key model organisms, namely mouse, rat, cynomolgus macaque, rhesus macaque, two related breeds (S. scrofa Duroc and C. familiaris boxer) and human reveal considerable variation in gene content. Key genes in toxicology and metabolism studies, such as the UGT2 family, CYP2D6, and SLCO1A2, displayed unique duplication patterns. Comparisons of 317 known human drug targets revealed surprising variation such as species-specific positive selection, duplication and higher occurrences of pseudogenized targets in beagle (41 genes) relative to minipig (19 genes). These data will facilitate the more effective use of animals in biomedical research. - Highlights: • Genomes of the minipig and beagle dog, two species used in pharmaceutical studies. • First systematic comparative genome analysis of human and six experimental animals. • Key drug toxicology genes display unique duplication patterns across species. • Comparison of 317 drug targets show species-specific evolutionary patterns.

60 APPLIED LIFE SCIENCES↗
NASA NTRS2000

Comparison of Commercial Electromagnetic Interface Test Techniques to NASA Electromagnetic Interference Test Techniques

This report documents the development of analytical techniques required for interpreting and comparing space systems electromagnetic interference test data with commercial electromagnetic interference test data using NASA Specification SSP 30237A "Space Systems Electromagnetic Emission and Susceptibility Requirements for Electromagnetic Compatibility." The PSpice computer simulation results and the laboratory measurements for the test setups under study compare well. The study results, however, indicate that the transfer function required to translate test results of one setup to another is highly dependent on cables and their actual layout in the test setup. Since cables are equipment specific and are not specified in the test standards, developing a transfer function that would cover all cable types (random, twisted, or coaxial), sizes (gauge number and length), and layouts (distance from the ground plane) is not practical.

Smith, V.↗
DOE OSTI2025

Evaluating Cloud Properties at Scott Base: Comparing Ceilometer Observations With ERA5, JRA55, and MERRA2 Reanalyses Using an Instrument Simulator

This study compares CL51 ceilometer observations made at Scott Base, Antarctica, with statistics from the ERA5, JRA55, and MERRA2 reanalyses. To enhance the comparison we use a lidar instrument simulator to derive cloud statistics from the reanalyses which account for instrumental factors. The cloud occurrence in the three reanalyses is slightly overestimated above 3 km, but displays a larger underestimation below 3 km relative to observations. Unlike previous studies, we see no relationship between relative humidity and cloud occurrence biases, suggesting that the cloud biases do not result from the representation of moisture. We also show that the seasonal variation of cloud occurrence and cloud fraction, defined as the vertically integrated cloud occurrence, are small in both the observations and the reanalyses. We also examine the quality of the cloud representation for a set of weather states derived from ERA5 surface winds. The variability associated with grouping cloud occurrence based on weather state is much larger than the seasonal variation, highlighting weather state is a strong control of cloud occurrence. All the reanalyses continue to display underestimates below 3 km and overestimates above 3 km for each weather state. But the variability in ERA5 statistics matches the changes in the observations better than the other reanalyses. We also use a machine learning scheme to estimate the quantity of supercooled liquid water cloud from the ceilometer observations. Ceilometer low-level supercooled liquid water cloud occurrences are considerably larger than values derived from the reanalyses, further highlighting the poor representation of low-level clouds in the reanalyses.

54 ENVIRONMENTAL SCIENCES↗
DOE OSTI2015

Effect of the number and position of nozzle holes on in- and near-nozzle dynamic characteristics of diesel injection

Despite the fact that all modern diesel engines use multi-hole injectors, single-hole injectors are frequently used to understand the fundamental properties of high-pressure diesel injections due to their axisymmetric design of the injector nozzles. A multi-hole injector accommodates many holes around the nozzle axis to deliver adequate amount of fuel with small orifices. The off-axis arrangement of the multi-hole injectors significantly alters the inter- and near-nozzle flow patterns compared to those of the single-hole injectors. This study compares the transient needle motion and near-nozzle flow characteristics of the single- and multi-hole (3-hole and 6-hole) diesel injectors to understand how the difference in hole arrangement and number affects the initial flow development of the diesel injectors. A propagation-based X-ray phase-contrast imaging technique was applied to compare the transient needle motion and near-nozzle flow characteristics of the single- and multi-hole injectors. The comparisons were made by dividing the entire injection process by three sub-stages: opening-transient, quasi-steady and closing-transient. (C) 2015 Elsevier Ltd. All rights reserved.

42 ENGINEERING↗
DOE OSTI2024

Origin of charge density wave in topological semimetals SrAl 4 and EuAl 4

Topological semimetals in BaAl 4 -type structure show many interesting behaviors, such as charge density wave (CDW) in SrAl 4 and EuAl 4 , but not the isostructural and isovalent BaAl 4 , SrGa 4 , and BaGa 4 . Here using Wannier functions based on density functional theory, we calculate the susceptibility functions with millions of k-points to reach the small q-vector and study the origin and driving force behind the CDW. Our comparative study reveals that the origin of the CDW in SrAl 4 and EuAl 4 is the strong electron-phonon coupling interaction for the transverse acoustic mode at small q-vector along the Γ-Z direction besides the maximum of the real part of the susceptibility function from the nested Fermi surfaces of the Dirac-like bands, which explains well the absence of CDW in the other closely related compounds in a good agreement with experiment. We also connect the different CDW behaviors in the Al compounds to the macroscopic elastic properties.

36 MATERIALS SCIENCE↗
DOE OSTI2015

Comprehensive identification and analysis of human accelerated regulatory DNA

It has long been hypothesized that changes in gene regulation have played an important role in human evolution, but regulatory DNA has been much more difficult to study compared with protein-coding regions. Recent large-scale studies have created genome-scale catalogs of DNase I hypersensitive sites (DHSs), which demark potentially functional regulatory DNA. To better define regulatory DNA that has been subject to human-specific adaptive evolution, we performed comprehensive evolutionary and population genetics analyses on over 18 million DHSs discovered in 130 cell types. We identified 524 DHSs that are conserved in nonhuman primates but accelerated in the human lineage (haDHS), and estimate that 70% of substitutions in haDHSs are attributable to positive selection. Through extensive computational and experimental analyses, we demonstrate that haDHSs are often active in brain or neuronal cell types; play an important role in regulating the expression of developmentally important genes, including many transcription factors such as SOX6, POU3F2, and HOX genes; and identify striking examples of adaptive regulatory evolution that may have contributed to human-specific phenotypes. More generally, our results reveal new insights into conserved and adaptive regulatory DNA in humans and refine the set of genomic substrates that distinguish humans from their closest living primate relatives.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2020

Bovine adapted transmissible mink encephalopathy is similar to L-BSE after passage through sheep with the VRQ/VRQ genotype but not VRQ/ARQ

Background: Transmissible mink encephalopathy (TME) is a fatal neurologic disease of farmed mink. Evidence indicates that TME and L-BSE are similar and may be linked in some outbreaks of TME. We previously transmitted bovine adapted TME (bTME) to sheep. The present study compared ovine passaged bTME (o-bTME) to C-BSE and L-BSE in transgenic mice expressing wild type bovine prion protein (TgBovXV). To directly compare the transmission efficiency of all prion strains in this study, we considered the attack rates and mean incubation periods. Additional methods for strain comparison were utilized including lesion profiles, fibril stability, and western blotting. Results: Sheep donor genotype elicited variable disease phenotypes in bovinized mice. Inoculum derived from a sheep with the VRQ/VRQ genotype (o-bTME VV ) resulted in an attack rate, incubation period, western blot profile, and neuropathology most similar to bTME and L-BSE. Conversely, donor material from a sheep with the VRQ/ARQ genotype (o-bTME AV ) elicited a phenotype distinct from o-bTME VV , bTME and L-BSE. The TSE with the highest transmission efficiency in bovinized mice was L-BSE. The tendency to efficiently transmit to TgBovXV mice decreased in the order bTME, C-BSE, o-bTME VV , and o-bTME AV . The transmission efficiency of L-BSE was approximately 1.3 times higher than o-bTMEVV and 3.2 times higher than o-bTME AV . Conclusions: Our findings provide insight on how sheep host genotype modulates strain genesis and influences interspecies transmission characteristics. Given that the transmission efficiencies of L-BSE and bTME are higher than C-BSE, coupled with previous reports of L-BSE transmission to mice expressing the human prion protein, continued monitoring for atypical BSE is advisable in order to prevent occurrences of interspecies transmission that may affect humans or other species.

59 BASIC BIOLOGICAL SCIENCES↗
NASA NTRS1982

Magsat scalar anomaly distribution - The global perspective

It is established that geographic coincidences exist between high-altitude Magsat scalar anomalies and major geologic and tectonic structures, with oceanic abyssal plains overlain by negative anomalies agreeing well in spatial extent and position and submarine platforms lying beneath positive scalar anomalies. In addition, geographic coincidence is found in the continents between many high-latitude positive anomalies and shields and cratons in North America, Eurasia and Australia. While these correlations are qualitative, they serve to identify regions for detailed study. The global distribution of anomalies provides a basis for comparative study which will be enhanced when reduced-to-pole versions of the Magsat data become available.

Frey, H.↗