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At least 1,045 records · Page 58

Optical Amplifier Based Space Solar Power

The objective was to design a safe optical power beaming system for use in space. Research was focused on identification of strategies and structures that would enable achievement near diffraction limited optical beam quality, highly efficient electrical to optical conversion, and high average power in combination in a single system. Efforts centered on producing high efficiency, low mass of the overall system, low operating temperature, precision pointing and tracking capability, compatibility with useful satellite orbits, component and system reliability, and long component and system life in space. A system based on increasing the power handled by each individual module to an optimum and the number of modules in the complete structure was planned. We were concerned with identifying the most economical and rapid path to commercially viable safe space solar power.

Fork, Richard L.↗

Enzyme Amplified Detection of Microbial Cell Wall Components

This proposal is MBL's portion of NASA's Johnson Space Center's Astrobiology Center led by Principal Investigator, Dr. David McKay, entitled: 'Institute for the Study of Biomarkers in Astromaterials.' Dr. Norman Wainwright is the principal investigator at MBL and is responsible for developing methods to detect trace quantities of microbial cell wall chemicals using the enzyme amplification system of Limulus polyphemus and other related methods.

Norman R Wainwright↗

The human power amplifier technology at the University of California, Berkeley

A human's ability to perform physical tasks is limited by physical strength, not by intelligence. We define "extenders" as a class of robot manipulators worn by humans to augment human mechanical strength, while the wearer's intellect remains the central control system for manipulating the extender. Our research objective is to determine the ground rules for the design and control of robotic systems worn by humans through the design, construction, and control of several prototype experimental direct-drive/non-direct-drive multi-degree-of-freedom hydraulic/electric extenders. The design of extenders is different from the design of conventional robots because the extender interfaces with the human on a physical level. Two sets of force sensors measure the forces imposed on the extender by the human and by the environment (i.e., the load). The extender's compliances in response to such contact forces were designed by selecting appropriate force compensators. This paper gives a summary of some of the selected research efforts related to Extender Technology, carried out during 1980s. The references, at the end of this article, give detailed description of the research efforts.

NASA Discipline Space Human Factors↗

Inactivity amplifies the catabolic response of skeletal muscle to cortisol

Severe injury or trauma is accompanied by both hypercortisolemia and prolonged inactivity or bed rest (BR). Trauma and BR alone each result in a loss of muscle nitrogen, albeit through different metabolic alterations. Although BR alone can result in a 2-3% loss of lean body mass, the effects of severe trauma can be 2- to 3-fold greater. We investigated the combined effects of hypercortisolemia and prolonged inactivity on muscle protein metabolism in healthy volunteers. Six males were studied before and after 14 days of strict BR using a model based on arteriovenous sampling and muscle biopsy. Fractional synthesis and breakdown rates of skeletal muscle protein were also directly calculated. Each assessment of protein metabolism was conducted during a 12-h infusion of hydrocortisone sodium succinate (120 microg/kg x h), resulting in blood cortisol concentrations that mimic severe injury (approximately 31 microg/dL). After 14 days of strict BR, hypercortisolemia increased phenylalanine efflux from muscle by 3-fold (P < 0.05). The augmented negative amino acid balance was the result of an increased muscle protein breakdown (P < 0.05) without a concomitant change in muscle protein synthesis. Muscle efflux of glutamine and alanine increased significantly after bed rest due to a significant increase in de novo synthesis (P < 0.05). Thus, inactivity sensitizes skeletal muscle to the catabolic effects of hypercortisolemia. Furthermore, these effects on healthy volunteers are analogous to those seen after severe injury.

Non-NASA Center↗

Insulin attenuates atrophy of unweighted soleus muscle by amplified inhibition of protein degradation

Unweighting atrophy of immature soleus muscle occurs rapidly over the first several days, followed by slower atrophy coinciding with increased sensitivity to insulin of in vitro protein metabolism. This study determined whether this increased sensitivity might account for the diminution of atrophy after 3 days of tall-cast hindlimb suspension. The physiological significance of the increased response to insulin in unweighted muscle was evaluated by analyzing in vivo protein metabolism for day 3 (48 to 72 hours) and day 4 (72 to 96 hours) of unweighting in diabetic animals either injected with insulin or not treated. Soleus from nontreated diabetic animals showed a similar loss of protein during day 3 (-16.2%) and day 4 (-14.5%) of unweighting, whereas muscle from insulin-treated animals showed rapid atrophy (-14.5%) during day 3 only, declining to just -3.1% the next day. Since fractional protein synthesis was similar for both day 3 (8.6%/d) and day 4 (7.0%/d) of unweighting in insulin-treated animals, the reduction in protein loss must be accounted for by a slowing of protein degradation due to circulating insulin. Intramuscular (IM) injection of insulin (600 nmol/L) stimulated in situ protein synthesis similarly in 4-day unweighted (+56%) and weight-bearing (+90%) soleus, even though unweighted muscle showed a greater in situ response of 2-deoxy-[3H]glucose uptake to IM injection of either insulin (133 nmol/L) or insulin-like growth factor-I (IGF-I) (200 nmol/L) than control muscle. These findings suggest that unweighted muscle is selectively more responsive in vivo to insulin, and that the slower atrophy after 3 days of unweighting was due to an increased effect of insulin on inhibiting protein degradation.

NASA Discipline Musculoskeletal↗

The QBO as Potential Amplifier and Conduit to Lower Altitudes of Solar Cycle Influence

In several papers, the solar cycle (SC) effect in the lower atmosphere has been linked to the Quasi-biennial Oscillation (QBO), which is generated primarily by small-scale gravity waves. Salby and Callaghan (2000) analyzed the observed zonal winds of the QBO over more than 40 years and found that it contains a relatively large SC signature at 20 km. Following up on an earlier 2D study with our global-scale Numerical Spectral Model (NSM), we discuss here a 3D study with the QBO under the influence of the SC. For a SC period of 10 years, the amplitude of the relative variations of radiative forcing is taken to vary for simplicity from 0.2% at the surface to 2% at 50 km to 20% at 100 km and above. Covering a limited time span of 40 years, this model produces in the lower stratosphere a relatively large modulation of the QBO, which appears to be related to the SC and is in qualitative agreement with the observations. Some of the energy in the QBO, confined to low latitudes primarily, is redistributed globally by the meridional circulation and planetary waves presumably, so that a measurable SC modulation is generated in the tropospheric temperatures of the polar regions. Further studies are needed, (1) to determine whether the effect is real and prevails in more extensive simulations and whether the results are robust when shorter integration steps are employed, and (2) to explore the mechanism(s) that may ample the apparent SC influence of the UV radiation extending into the lower atmosphere. Quasi-decadal oscillations, generated internally by the QBO interacting with the seasonal cycles, may interfere with or aid the SC effect.

Mayr, Hans G.↗

QBO as Potential Amplifier of Solar Cycle Influence

The solar cycle (SC) effect in the lower atmosphere has been linked observationally to the quasi-biennial oscillation (QBO) of the zonal circulation. Salby and Callaghan (2000) in particular analyzed the QBO covering more than 40 years and found that it contains a large SC signature at 20 km. We discuss a 3D study in which we simulate the QBO under the influence of the SC. For a SC period of 10 years, the relative amplitude of radiative forcing is taken to vary with height: 0.2% (surface), 2% (50 km), 20% (100 km and above). This model produces in the lower stratosphere a relatively large modulation of the QBO, which appears to come from the SC and qualitatively agrees with the observations. The modulation of the QBO, with constant phase relative to the SC, is shown to persist at least for 50 years, and it is induced by a SC modulated annual oscillation that is hemispherically symmetric and confined to low latitudes.

Mayr, Hans G.↗

The Effects of Low Dose-Rate Ionizing Radiation on the Shapes of Transients in the LM124 Operational Amplifier

Shapes of single event transients (SETs) in a linear bipolar circuit (LM124) change with exposure to total ionizing dose (TID) radiation. SETs shape changes are a direct consequence of TID-induced degradation of bipolar transistor gain. A reduction in transistor gain causes a reduction in the drive current of the current sources in the circuit, and it is the lower drive current that most affects the shapes of large amplitude SETs.

Buchner, Stephen↗

Fiber Amplifier Report for NEPP 2008

Ongoing qualification activities of LiNbO3 modulators. Passive (unpumped) radiation testing of Er-, Yb-, and Er/Yb-doped fibers: a) Yb-doped fibers exhibit higher radiation resistance than Er-doped fibers; b) Er/Yb co-doped fibers exhibit largest radiation resistance. Active (pumped) radiation testing of Yb-doped fibers conducted at NASA GSFC: a) Typical decay behavior observed; b) No comparison could be made to other fibers due to problems with test setup. Development of new high power fiber terminations.

Thomes, Joe↗

High Power Amplifier and Power Supply

A document discusses the creation of a high-voltage power supply (HVPS) that is able to contain voltages up to -20 kV, keep electrical field strengths to below 200 V/mil (approximately equal to 7.87 kV/mm), and can provide a 200-nanosecond rise/fall time focus modulator swinging between cathode potential of 16.3 kV and -19.3 kV. This HVPS can protect the 95-GHz, pulsed extended interaction klystron (EIK) from arcs/discharges from all sources, including those from within the EIK fs vacuum envelope. This innovation has a multi-winding pulse transformer design, which uses new winding techniques to provide the same delays and rise/fall times (less than 10 nanoseconds) at different potential levels ranging from -20 kV to -16 kV. Another feature involves a high-voltage printed-wiring board that was corona-free at -20 kV DC with a 3- kV AC swing. The corona-free multilayer high-voltage board is used to simulate fields of less than 200 V/mil (approximately equal to 7.87 kV/mm) at 20 kV DC. Drive techniques for the modulator FETs (field-effect transistors) (four to 10 in a series) were created to change states (3,000-V swing) without abrupt steps, while still maintaining required delays and transition times. The packing scheme includes a potting mold to house a ten-stage modulator in the space that, in the past, only housed a four-stage modulator. Problems keeping heat down were solved using aluminum oxide substrate in the high-voltage section to limit temperature rise to less than 10 while withstanding -20 kV DC voltage and remaining corona-free.

Duong, Johnny↗

Wide-temperature integrated operational amplifier

The present invention relates to a reference current circuit. The reference circuit comprises a low-level current bias circuit, a voltage proportional-to-absolute temperature generator for creating a proportional-to-absolute temperature voltage (VPTAT), and a MOSFET-based constant-IC regulator circuit. The MOSFET-based constant-IC regulator circuit includes a constant-IC input and constant-IC output. The constant-IC input is electrically connected with the VPTAT generator such that the voltage proportional-to-absolute temperature is the input into the constant-IC regulator circuit. Thus the constant-IC output maintains the constant-IC ratio across any temperature range.

Mojarradi, Mohammad↗