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All sources NASA NTRS DOE OSTI

DOE OSTI2021

Measuring Signatures of Fuel Irradiation in Large Particle Samples

Understanding the operating history of a nuclear facility is one of the key goals in nuclear safeguards, enabling the verification of declared activities. This is accomplished via a number of mechanisms, including the analysis of samples collected at the facility. The best metrics for understanding and verifying the history of nuclear fuel are (1) actinide isotopic content and (2) actinide inter-element ratios. While techniques have long existed for measuring these values with high accuracy and precision in bulk samples, as samples become smaller – such as may be collected in environmental collection – new methods are required both for clean processing of pure samples, and for analysis of these small samples. This study describes a new extraction chromatography technique for recovering U, Pu, and Am from single small aliquots, and advanced mass spectrometry methods for high-precision and high-accuracy analysis of trace and ultra-trace levels of actinides. These techniques are applied to particle samples cut from fuel from a historic nuclear reactor. Ages calculated from Pu–Am chronometry of particles are in excellent agreement with the known operating history of the reactor.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

DOE OSTI2020

An in situ shearing x-ray measurement system for exploring structures and dynamics at the solid–liquid interface

Revealing interfacial structure and dynamics has been one of the essential thematic topics in material science and condensed matter physics. Synchrotron-based x-ray scattering techniques can deliver unique and insightful probing of interfacial structures and dynamics, in particular, in reflection geometries with higher surface and interfacial sensitivity than transmission geometries. We demonstrate the design and implementation of an in situ shearing x-ray measurement system, equipped with both inline parallel-plate and cone-and-plate shearing setups and operated at the advanced photon source at Argonne National Laboratory, to investigate the structures and dynamics of end-tethered polymers at the solid-liquid interface. With a precise lifting motor, a micrometer-scale gap can be produced by aligning two surfaces of a rotating upper shaft and a lower sample substrate. A torsional shear flow forms in the gap and applies tangential shear forces on the sample surface. The technical combination with nanoscale rheology and the utilization of in situ x-ray scattering allow us to gain fundamental insights into the complex dynamics in soft interfaces under shearing. In this work, we demonstrate the technical scope and experimental capability of the in situ shearing x-ray system through the measurements of charged polymers at both flat and curved interfaces upon shearing. Furthermore, through the in situ shearing x-ray scattering experiments integrated with theoretical simulations, we aim to develop a detailed understanding of the short-range molecular structure and mesoscale ionic aggregate morphology, as well as ion transport and dynamics in soft interfaces, thereby providing fundamental insight into a long-standing challenge in ionic polymer brushes with a significant technological impact.

36 MATERIALS SCIENCE↗

DOE OSTI2024

Multipoint-BAX: a new approach for efficiently tuning particle accelerator emittance via virtual objectives

Abstract Although beam emittance is critical for the performance of high-brightness accelerators, optimization is often time limited as emittance calculations, commonly done via quadrupole scans, are typically slow. Such calculations are a type of multipoint query , i.e. each query requires multiple secondary measurements. Traditional black-box optimizers such as Bayesian optimization are slow and inefficient when dealing with such objectives as they must acquire the full series of measurements, but return only the emittance, with each query. We propose a new information-theoretic algorithm, Multipoint-BAX , for black-box optimization on multipoint queries, which queries and models individual beam-size measurements using techniques from Bayesian Algorithm Execution (BAX). Our method avoids the slow multipoint query on the accelerator by acquiring points through a virtual objective , i.e. calculating the emittance objective from a fast learned model rather than directly from the accelerator. We use Multipoint-BAX to minimize emittance at the Linac Coherent Light Source (LCLS) and the Facility for Advanced Accelerator Experimental Tests II (FACET-II). In simulation, our method is 20× faster and more robust to noise compared to existing methods. In live tests, it matched the hand-tuned emittance at FACET-II and achieved a 24% lower emittance than hand-tuning at LCLS. Our method represents a conceptual shift for optimizing multipoint queries, and we anticipate that it can be readily adapted to similar problems in particle accelerators and other scientific instruments.

43 PARTICLE ACCELERATORS↗

NASA NTRS1998

Thin Film Sensors for Minimally-Intrusive Measurements in Harsh High Temperature Environment

Advanced thin film sensors are being developed to provide accurate surface temperature, heat flux and strain measurements for components used in hostile propulsion environments. These sensors are sputter deposited and microfabricated directly onto the test articles with no additional bonding agent. The thickness of the sensors is only a few micrometers which creates minimal disturbance of the gas flow over the test surface. Thus thin film sensors have the advantage over conventional wire- based sensors by providing minimally intrusive measurement and having a faster response. These thin film sensors are being developed for characterization of advanced materials and structures in hostile, high-temperature environments, and for validation of design codes. This paper presents the advances of three high temperature thin film sensor technologies developed at NASA Lewis Research Center: thermocouples, heat-flux gages and strain gages. The fabrication techniques of these thin film sensors which include physical vapor deposition, photolithography patterning and lead Wire attachment are described. Sensors demonstrations on a variety of engine materials, including superalloys, ceramics and advanced ceramic matrix composites, in several hostile, high-temperature test environments are presented. The advantages and limitations of thin film sensor technology are also discussed.

Lei, Jih-Fen↗

NASA NTRS2002

Leveraging Improvements in Precipitation Measuring from GPM Mission to Achieve Prediction Improvements in Climate, Weather and Hydrometeorology

The main scientific goal of the GPM mission, currently planned for start in the 2007 time frame, is to investigate important scientific problems arising within the context of global and regional water cycles. These problems cut across a hierarchy of scales and include climate-water cycle interactions, techniques for improving weather and climate predictions, and better methods for combining observed precipitation with hydrometeorological prediction models for applications to hazardous flood-producing storms, seasonal flood/draught conditions, and fresh water resource assessments. The GPM mission will expand the scope of precipitation measurement through the use of a constellation of some 9 satellites, one of which will be an advanced TRMM-like "core" satellite carrying a dual-frequency Ku-Ka band precipitation radar and an advanced, multifrequency passive microwave radiometer with vertical-horizontal polarization discrimination. The other constellation members will include new dedicated satellites and co-existing Operational/research satellites carrying similar (but not identical) passive microwave radiometers. The goal of the constellation is to achieve approximately 3-hour sampling at any spot on the globe. The constellation's orbit architecture will consist of a mix of sun-synchronous and non-sun-synchronous satellites with the core satellite providing measurements of cloud-precipitation microphysical processes plus calibration-quality rainrate retrievals to be used with the other retrieval information to ensure bias-free constellation coverage. GPM is organized internationally, currently involving a partnership between NASA in the US and the National Space Development Agency in Japan. Additionally, the program is actively pursuing agreements with other international partners and domestic scientific agencies and institutions, as well as participation by individual scientists from academia, government, and the private sector to fulfill mission goals and to pave the way for what ultimately is expected to become an internationally-organized operational global precipitation observing system. Notably, the broad societal applications of GPM are reflected in the United Nation s identification of this mission as a foremost candidate for its Peaceful Uses of Space Program. In this presentation, an overview of the GPM mission design will be presented, followed by an explanation of its scientific agenda as an outgrowth of making improvements in rain retrieval accuracy, microphysics dexterity, sampling frequency, and global coverage. All of these improvements offer new means to observe variability in precipitation and water cycle fluxes and to achieve improved predictability of weather, climate, and hydrometeorology. Specifically, the scientific agenda of GPM has been designed to leverage the measurement improvements to improve prognostic model performance, particularly quantitative precipitation forecasting and its linked phenomena at short, intermediate, and extended time scales. The talk will address how GPM measurements will enable better detection of accelerations and decelerations in regional and global water cycle processes and their relationship to climate variability, better impacts of precipitation data assimilation on numerical weather prediction and global climate reanalysis, and better performance from basin scale hydrometeorological models for short and long term flood-drought forecasting and seasonal fresh water resource assessment. Improved hydrometeorological forecasting will be possible by using continuous global precipitation observations to obtain better closure in water budgets and to generate more realistic forcing of the models themselves to achieve more accurate estimates of interception, infiltration, evaporation/transpiration fluxes, storage, and runoff.

Smith, Eric A.↗

NASA NTRS2003

Anticipated Improvements in Precipitation Physics and Understanding of Water Cycle from GPM Mission

The GPM mission is currently planned for start in the late-2007 to early-2008 time frame. Its main scientific goal is to help answer pressing scientific problems arising within the context of global and regional water cycles. These problems cut across a hierarchy of scales and include climate-water cycle interactions, techniques for improving weather and climate predictions, and better methods for combining observed precipitation with hydrometeorological prediction models for applications to hazardous flood-producing storms, seasonal flood/draught conditions, and fresh water resource assessments. The GPM mission will expand the scope of precipitation measurement through the use of a constellation of some 9 satellites, one of which will be an advanced TRMM-like core satellite carrying a dual-frequency Ku-Ka band precipitation radar and an advanced, multifrequency passive microwave radiometer with vertical-horizontal polarization discrimination. The other constellation members will include new dedicated satellites and co-existing operational/research satellites carrying similar (but not identical) passive microwave radiometers. The goal of the constellation is to achieve approximately 3-hour sampling at any spot on the globe -- continuously. The constellation s orbit architecture will consist of a mix of sun-synchronous and non-sun-synchronous satellites with the core satellite providing measurements of cloud-precipitation microphysical processes plus calibration-quality rainrate retrievals to be used with the other retrieval information to ensure bias-free constellation coverage. GPM is organized internationally, involving existing, pending, projected, and under-study partnerships which will link NASA and NOAA in the US, NASDA in Japan, ESA in Europe, ISRO in India, CNES in France, and possibly AS1 in Italy, KARI in South Korea, CSA in Canada, and AEB in Brazil. Additionally, the program is actively pursuing agreements with other international collaborators and domestic scientific agencies and institutions, as well as participation by individual scientists from academia, government, and the private sector to fulfill mission goals and to pave the way for what is expected to become an internationally-organized operational global precipitation observing system. Notably, the broad societal applications of GPM are reflected in the United Nation s identification of GPM as a foremost candidate for its Peaceful Uses of Space Program. An overview of the GPM mission design is given, followed by an explanation of its scientific agenda as an outgrowth of making improvements in rain retrieval accuracy, microphysics dexterity, sampling frequency, and global coverage. All of these improvements offer new means to observe variability in precipitation and water cycle fluxes and to achieve improved predictability of weather, climate, and hydrometeorology. Specifically, the scientific agenda of GPM has been designed to leverage the measurement improvements to improve prognostic model performance, particularly quantitative precipitation forecasting and its linked phenomena at short, intermediate, and extended time scales. The talk addresses how GPM measurements will enable better detection of accelerations and decelerations in regional and global water cycle processes and their relationship to climate variability, better impacts of precipitation data assimilation on numerical weather prediction and global climate reanalysis, and better performance from basin scale hydrometeorological models for short and long term flood-drought forecasting and seasonal fresh water resource assessment. These improvements become possible by using more accurate, more microphysically-centric, more frequent, and fully global precipitation observations to achieve better water budget closure and to provide more realistic forcing and assessment of prediction models.

Smith, Eric A.↗

NASA NTRS1992

Optimization techniques applied to passive measures for in-orbit spacecraft survivability

The purpose of this research is to provide Space Station Freedom protective structures design insight through the coupling of design/material requirements, hypervelocity impact phenomenology, meteoroid and space debris environment sensitivities, optimization techniques and operations research strategies, and mission scenarios. The goals of the research are: (1) to develop a Monte Carlo simulation tool which will provide top level insight for Space Station protective structures designers; (2) to develop advanced shielding concepts relevant to Space Station Freedom using unique multiple bumper approaches; and (3) to investigate projectile shape effects on protective structures design.

Mog, Robert A.↗

DOE OSTI2020

Characterization of Rare-earth Doped Thermal Barrier Coatings for Phosphor Thermometry

Thermal Barrier Coatings have been extensively used to protect and insulate the metallic components in turbine engines from extreme environments to achieve higher turbine inlet temperatures, resulting in an increase in combined engine cycle efficiency, lowering NOx emissions and fuel consumption. Additionally, as the major failure mechanisms determining lifetime are thermally activated during engine operation, uncertainty in temperature measurements affects lifetime prediction. Early detection of Thermal Barrier Coatings spallation symptoms, associated with local delamination induced temperature changes, can reduce forced engine outages. Further improvements are envisioned with the development of more reliable measurement techniques. For this purpose, Phosphor Thermometry has been considered a promising method for precision monitoring of turbine blade coatings that contain embedded phosphor dopants. In this work, a modified four-flux Kubelka-Munk model for luminescent rare-earth doped Thermal Barrier Coating configurations supported the design and the fabrication of viable sensing coatings for potential industrial implementation. Phosphor Thermometry instrumentation was developed with the objective of expanding capabilities of the technique, using a synchronized acquisition method on sensing coatings. Experiments on an innovative Erbium-Europium co-doped Yttria-Stabilized Zirconia coating have demonstrated the effectiveness of this advanced Phosphor Thermometry instrument with enhanced sensitivity and extended temperature range. Delamination progression monitoring was achieved for the first time using a Thermal Barrier Coating configuration subjected to indentation that includes a thin luminescent layer deposited on the surface and associating the multi-layer configuration with a predictive model that evaluates the advancement of the degradation of the coatings. To further ensure the integrity of the phosphor doped coatings, synchrotron X-ray diffraction was performed to characterize the specific residual strains and thermal expansion of the materials, determining mechanical robustness and compatibility with state-of-the-art Thermal Barrier Coatings. The outcomes of this work pave the way for in-situ temperature measurements on phosphor-doped turbine blade coatings with increased performance and accuracy.

Fouliard, Quentin↗

DOE OSTI2024

Advances in mass spectrometry-enabled multiomics at single-cell resolution

We report biological organisms are multifaceted, intricate systems where slight perturbations can result in extensive changes in gene expression, protein abundance and/or activity, and metabolic flux. These changes occur at different timescales, spatially across cells of heterogeneous origins, and within single-cells. Hence, multimodal measurements at the smallest biological scales are necessary to capture dynamic changes in heterogeneous biological systems. Of the analytical techniques used to measure biomolecules, mass spectrometry (MS) has proven to be a powerful option due to its sensitivity, robustness, and flexibility with regard to the breadth of biomolecules that can be analyzed. Recently, many studies have coupled MS to other analytical techniques with the goal of measuring multiple modalities from the same single-cell. It is with these concepts in mind that we focus this review on MS-enabled multiomic measurements at single-cell or near-single- cell resolution.

47 OTHER INSTRUMENTATION↗

DOE OSTI2022

Current advances on Talbot–Lau x-ray imaging diagnostics for high energy density experiments (invited)

Talbot–Lau x-ray interferometry is a refraction-based diagnostic that can map electron density gradients through phase-contrast methods. The Talbot–Lau x-ray deflectometry (TXD) diagnostics have been deployed in several high energy density experiments. To improve diagnostic performance, a monochromatic TXD was implemented on the Multi-Tera Watt (MTW) laser using 8 keV multilayer mirrors (Δθ/θ = 4.5%-5.6%). Copper foil and wire targets were irradiated at 10 14 –10 15 W/cm 2 . Laser pulse length (~10 to 80 ps) and backlighter target configurations were explored in the context of Moiré fringe contrast and spatial resolution. Foil and wire targets delivered increased contrast <30%. The best spatial resolution (<6 μm) was measured for foils irradiated 80° from the surface. Further TXD diagnostic capability enhancement was achieved through the development of advanced data postprocessing tools. The Talbot Interferometry Analysis (TIA) code enabled x-ray refraction measurements from the MTW monochromatic TXD. Additionally, phase, attenuation, and dark-field maps of an ablating x-pinch load were retrieved through TXD. The images show a dense wire core of ~60 μm diameter surrounded by low-density material of ~40 μm thickness with an outer diameter ratio of ~2.3. Attenuation at 8 keV was measured at ~20% for the dense core and ~10% for the low-density material. Instrumental and experimental limitations for monochromatic TXD diagnostics are presented. Enhanced postprocessing capabilities enabled by TIA are demonstrated in the context of high-intensity laser and pulsed power experimental data analysis. Significant advances in TXD diagnostic capabilities are presented. Furthermore, these results inform future diagnostic technique upgrades that will improve the accuracy of plasma characterization through TXD.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

DOE OSTI2023

Machine-Learned Structure-Property Relationship in Metallic Glasses (Final Report)

The goal of the proposed work was to gain the ability to predict properties from the known coordinates (relative positions) of atoms in a metallic glass, presuming that information about which regions of the glass are fertile for rearrangment (defects) are encoded in this structural information. This goal is important to the science of metallic glasses. This research of applied machine learning methods to automate the development of a relationship between structural measures and thermally and stress-activated events in the metallic glass. In this way, the work aimed to building a bridge between structure and properties for this class of materials. The work is expected to have timely impact on guiding the tuning of internal structures of metallic glasses for desired properties. It also represents an advance in applying machine learning techniques to discerning the properties of materials.

36 MATERIALS SCIENCE↗

DOE OSTI2025

Integration and Demonstration of Monitoring, Modeling, and Prediction of DV-1 Amendment Performance at the Bench Scale: DV-1 Amendment Demonstration

During fiscal years 2024 and 2025, the U.S. Department of Energy’s Hanford Field Office commissioned Pacific Northwest National Laboratory to conduct applied research aimed at reducing the cost, time, and uncertainty associated with in situ treatment of vadose zone contaminants at the Hanford Site. This report outlines the integration of three key research efforts into a meso-scale demonstration designed to advance field-scale solutions that aim to (1) optimize the delivery of chemical amendments to contaminated soils, (2) reduce uncertainty in amendment delivery performance assessment using advanced monitoring techniques, and (3) provide real-time insights into when and where amendment-induced precipitation reactions occur in the subsurface. To achieve these objectives, the tank-scale (~ 1 cubic meter) Geophysical Imaging of Flow and Transport (GIFT) system was developed. GIFT enables experimental testing of amendment delivery while incorporating automated multi-modal monitoring approaches, including pressure measurements, direct fluid sampling, and remote time-lapse geophysical imaging. The data generated from these monitoring techniques will serve as inputs for a generative artificial-intelligence-driven digital twin – a numerical simulation model designed to honor observed data while quantifying uncertainty in simulation accuracy. Using this simulator, researchers will refine an amendment injection strategy to maximize delivery efficiency within a low-permeability soil zone. Monitoring data will be interpreted through simulated outputs to enhance understanding of the injection process. The efficacy of this integrated approach will be evaluated through direct sampling at the conclusion of the experiment.

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

NASA NTRS1981

Microwave measurement of stratospheric and mesospheric ozone

It is pointed out that ozone has a rich rotational spectrum with many lines at millimeter wavelengths. Measurement of these lines can provide a means of remotely sensing stratospheric and mesospheric ozone. Technology has recently advanced to the state where it is reasonable to consider monitoring upper atmospheric O3 on a global scale by microwave radiometers in earth orbit. An investigation indicates that approximately 1% accuracy and approximately 2 km vertical resolution O3 mixing ratio measurements are reasonable goals for limb-viewing microwave radiometers in earth orbit. Mesospheric ozone can also be measured by the considered techniques using stronger (but more temperature-sensitive) O3 lines. A balloon-borne microwave limb sounder has recently been constructed to test the practical limitations on the measurement concepts. Also under study is a microwave limb sounder for operation in earth orbit.

Waters, J. W.↗

NASA NTRS1983

Model helicopter rotor high-speed impulsive noise: Measured acoustics and blade pressures

A 1/17-scale research model of the AH-1 series helicopter main rotor was tested. Model-rotor acoustic and simultaneous blade pressure data were recorded at high speeds where full-scale helicopter high-speed impulsive noise levels are known to be dominant. Model-rotor measurements of the peak acoustic pressure levels, waveform shapes, and directively patterns are directly compared with full-scale investigations, using an equivalent in-flight technique. Model acoustic data are shown to scale remarkably well in shape and in amplitude with full-scale results. Model rotor-blade pressures are presented for rotor operating conditions both with and without shock-like discontinuities in the radiated acoustic waveform. Acoustically, both model and full-scale measurements support current evidence that above certain high subsonic advancing-tip Mach numbers, local shock waves that exist on the rotor blades ""delocalize'' and radiate to the acoustic far-field.

Boxwell, D. A.↗

NASA NTRS1986

Automation of planetary spacecraft

The development of autonomous spacecraft from 1960 to the present is traced within a framework of the definitions and measures of the level of autonomy. The attainment of milestones in the level of autonomy in spacecraft guidance and control is described in terms of the Mariner, Viking, Voyager, Galileo and Mark II (under development) spacecraft. The constant interplay between the definition of scientific mission goals and available technological capabilities is explored, along with current efforts to implement AI techniques and advanced software in spacecraft to allow reliable functioning in stressful conditions.

Varsi, G.↗

NASA NTRS1991

Cosmic dust: Laboratory analyses of extremely small particles

A discussion of cosmic dust, its classification, the usefulness of its analysis, and problems associated with its analysis is presented. All measurements on stratospheric dust particles presented here were made with secondary ion mass spectrometry (SIMS). The SIMS technique turns out to be an extremely useful tool in the study of very small particles and made a number of firsts possible. The isotopic composition of cosmic dust particles were measured for the first time. It was also the first time that it was possible to measure the abundances of the rare earth elements in these particles. However, the most important advance this work represents is that both trace elemental and isotopic abundances were successfully measured in the same particles. Thus, for the first time, it is possible to compare isotopic and trace element abundance data of the same cosmic dust particles.

Stadermann, Frank J.↗

NASA NTRS2003

A Physical Validation Program for the GPM Mission

The GPM mission is currently planned for start in the late 2007 - early 2008 time frame. Its main scientific goal is to help answer pressing scientific problems arising within the context of global and regional water cycling. These problems cut across a hierarchy of scales and include climate-water cycle interactions, techniques for improving weather and climate predictions, and better methods for combining observed precipitation with hydrometeorological prediction models for applications to hazardous flood-producing storms, seasonal flood draught conditions, and fresh water resource assessments. The GPM mission will expand the scope of precipitation measurement through the use of a constellation of some 9 satellites, one of which will be an advanced TRMM-like core satellite carrying a dual-frequency Ku-Ka band precipitation radar and an advanced, multifrequency passive microwave radiometer with vertical-horizontal polarization discrimination. The other constellation members will include new dedicated satellites and co-existing operational/research satellites carrying similar (but not identical) passive microwave radiometers. The goal of the constellation is to achieve approximately 3-hour sampling at any spot on the globe -- continuously. The constellation's orbit architecture will consist of a mix of sun-synchronous and non-sun-synchronous satellites with the core satellite providing measurements of cloud-precipitation microphysical processes plus calibration-quality rainrate retrievals to be used with the other retrieval information to ensure bias-free constellation coverage. A major requirement before the retrieved rainfall information generated by the GPM mission can be used effectively by prognostic models to improve weather forecasts, hydrometeorological forecasts, and climate model reanalysis simulations is a capability to quantify the error characteristics of the retrievals. A solution for this problem has been upheld in past precipitation missions because of the lack of suitable error modeling systems incorporated into the validation programs and data distribution systems. An overview of how NASA intends to overcome this problem for the GPM mission using a physically-based error modeling approach within a multi-faceted validation program is described. The solution is to first identify specific user requirements and then determine the most stringent of these requirements that embodies all essential error characterization information needed by the entire user community. In the context of NASA s scientific agenda for the GPM mission, the most stringent user requirement is found within the data assimilation community. The fundamental theory of data assimilation vis-a-vis ingesting satellite precipitation information into the pre-forecast initializations is based on quantifying the conditional bias and precision errors of individual rain retrievals, and the space-time structure of the precision error (i.e., the spatial-temporal error covariance). By generating the hardware and software capability to produce this information in a near real-time fashion, and to couple the derived quantitative error properties to the actual retrieved rainrates, all key validation users can be satisfied. The talk will describe the essential components of the hardware and software systems needed to generate such near real-time error properties, as well as the various paradigm shifts needed within the validation community to produce a validation program relevant to the precipitation user community.

Smith, Eric A.↗

NASA NTRS1996

Predicting sudden cardiac death from T wave alternans of the surface electrocardiogram: promise and pitfalls

Sudden cardiac death remains a preeminent public health problem. Despite advances in preventative treatment for patients known to be at risk, to date we have been able to identify, and thus treat, only a small minority of these patients. Therefore, there is a major need to develop noninvasive diagnostic technologies to identify patients at risk. Recent studies have demonstrated that measurement of microvolt-level T wave alternans is a promising technique for the accurate identification of patients at risk for ventricular arrhythmias and sudden cardiac death. In this article, we review the clinical data establishing the relationship between microvolt T wave alternans and susceptibility to ventricular arrhythmias. We also review the methods and technology that have been developed to measure microvolt levels of T wave alternans noninvasively in broad populations of ambulatory patients. In particular, we examine techniques that permit the accurate measurement of T wave alternans during exercise stress testing.

Review, Tutorial↗