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All sourcesNASA NTRSDOE OSTI
NASA NTRS2007

Hypovolemia Induced Orthostatic Hypotension in Presyncopal Astronauts and Normal Subjects Relates to Hypo-Sympathetic Responsiveness

Circulating blood volume is reduced during spaceflight, leaving astronauts hemodynamically compromised after landing. Because of this hypovolemia, crew members are able to withstand a postflight 10 minute upright tilt test only if they are able to mount a hyper-sympathetic response. Previous work from this laboratory has shown that about 30% of astronauts, primarily female, have postflight sympathetic responses to tilt that are equal to or less than their preflight responses and thus, they become presyncopal. Part of the mission of the cardiovascular lab at the Johnson Space Center is to identify susceptible crewmembers before flight so that individualized countermeasures can be prescribed. The goal of this study was to develop a ground based model of hypovolemia that could be used for this purpose We tested the hypothesis that hypovolemia alone, in the absence of spaceflight, would reproduce the landing day rate of presyncope during upright tilt in normal volunteers. Further, we hypothesized that, during hypovolemia, subjects who had sympathetic responses that were equal to or less than their normovolemic responses would become presyncopal during upright tilt tests. We studied 20 subjects, 13 male and 7 female, on two separate occasions: during normovolemia and hypovolemia. We induced hypovolemia with intravenous furosemide 40 hours prior to the experiment day, followed by a 10MEq Na diet. On the normovolemia and hypovolemia test days, plasma volume, tilt tolerance and supine and standing arterial pressure, heart rate and plasma norepinephrine levels were measured. A two factor, repeated measures analysis of variance was performed to examine the differences between group (presyncopal vs. non-presyncopal) and day (normovolemia vs. hypovolemia) effects. There were no differences in baseline arterial pressure between normovolemia and hypovolemia or between presyncopal and non-presyncopal groups, but heart rates were higher with hypovolemia in both groups (presyncopal: 70 5 bpm vs. 63 3 bpm, P = 0.003, non-presyncopal: 59 2 bpm vs. 52 2 bpm, P = 0.003). Similar to patterns reported after flight, non-presyncopal subjects had greater norepinephrine responses to tilt during hypovolemia compared to normovolemia (580 79 vs. 298 37 pg/ml, P < 0.05), but presyncopal subjects did not (180 44 vs. 145 32 pg/ml, P = NS). This new model has the potential to accelerate the development of countermeasures and save flight resources. It can be used to identify astronauts who will become presyncopal on landing day, so that prospective, individualized countermeasures can be developed. In addition, it can also be used to screen candidate countermeasures prior to requests for bed rest or inflight resources.

Meck, Janice V.↗
NASA NTRS2007

Effect of EMIC Wave Normal Angle Distribution on Relativistic Electron Scattering in Outer RB

We present the equatorial and bounce average pitch angle diffusion coefficients for scattering of relativistic electrons by the H+ mode of EMIC waves. Both the model (prescribed) and self consistent distributions over the wave normal angle are considered. The main results of our calculation can be summarized as follows: First, in comparison with field aligned waves, the intermediate and highly oblique waves reduce the pitch angle range subject to diffusion, and strongly suppress the scattering rate for low energy electrons (E less than 2 MeV). Second, for electron energies greater than 5 MeV, the |n| = 1 resonances operate only in a narrow region at large pitch-angles, and despite their greatest contribution in case of field aligned waves, cannot cause electron diffusion into the loss cone. For those energies, oblique waves at |n| greater than 1 resonances are more effective, extending the range of pitch angle diffusion down to the loss cone boundary, and increasing diffusion at small pitch angles by orders of magnitude.

Khazanov, G. V.↗
NASA NTRS2006

Controlled Vocabularies Boost International Participation and Normalization of Searches

The Global Change Master Directory's (GCMD) science staff set out to document Earth science data and provide a mechanism for it's discovery in fulfillment of a commitment to NASA's Earth Science progam and to the Committee on Earth Observation Satellites' (CEOS) International Directory Network (IDN.) At the time, whether to offer a controlled vocabulary search or a free-text search was resolved with a decision to support both. The feedback from the user community indicated that being asked to independently determine the appropriate 'English" words through a free-text search would be very difficult. The preference was to be 'prompted' for relevant keywords through the use of a hierarchy of well-designed science keywords. The controlled keywords serve to 'normalize' the search through knowledgeable input by metadata providers. Earth science keyword taxonomies were developed, rules for additions, deletions, and modifications were created. Secondary sets of controlled vocabularies for related descriptors such as projects, data centers, instruments, platforms, related data set link types, and locations, along with free-text searches assist users in further refining their search results. Through this robust 'search and refine' capability in the GCMD users are directed to the data and services they seek. The next step in guiding users more directly to the resources they desire is to build a 'reasoning' capability for search through the use of ontologies. Incorporating twelve sets of Earth science keyword taxonomies has boosted the GCMD S ability to help users define and more directly retrieve data of choice.

Olsen, Lola M.↗
NASA NTRS2007

Going Below Minimums: The Efficacy of Display Enhanced/Synthetic Vision Fusion for Go-Around Decisions during Non-Normal Operations

The use of enhanced vision systems in civil aircraft is projected to increase rapidly as the Federal Aviation Administration recently changed the aircraft operating rules under Part 91, revising the flight visibility requirements for conducting approach and landing operations. Operators conducting straight-in instrument approach procedures may now operate below the published approach minimums when using an approved enhanced flight vision system that shows the required visual references on the pilot's Head-Up Display. An experiment was conducted to evaluate the complementary use of synthetic vision systems and enhanced vision system technologies, focusing on new techniques for integration and/or fusion of synthetic and enhanced vision technologies and crew resource management while operating under these newly adopted rules. Experimental results specific to flight crew response to non-normal events using the fused synthetic/enhanced vision system are presented.

Prinzel, Lawrence J., III↗
NASA NTRS2007

Effect of EMIC Wave Normal Angle Distribution on Relativistic Electron Scattering Based on the Newly Developed Self-consistent RC/EMIC Waves Model by Khazanov et al. [2006]

It is well known that the effects of EMIC waves on RC ion and RB electron dynamics strongly depend on such particle/wave characteristics as the phase-space distribution function, frequency, wave-normal angle, wave energy, and the form of wave spectral energy density. Therefore, realistic characteristics of EMIC waves should be properly determined by modeling the RC-EMIC waves evolution self-consistently. Such a selfconsistent model progressively has been developing by Khaznnov et al. [2002-2006]. It solves a system of two coupled kinetic equations: one equation describes the RC ion dynamics and another equation describes the energy density evolution of EMIC waves. Using this model, we present the effectiveness of relativistic electron scattering and compare our results with previous work in this area of research.

Khazanov, G. V.↗
NASA NTRS2007

Measurement of Primary Ejecta From Normal Incident Hypervelocity Impact on Lunar Regolith Simulant

The National Aeronautics and Space Administration (NASA) continues to make progress toward long-term lunar habitation. Critical to the design of a lunar habitat is an understanding of the lunar surface environment. A subject for further definition is the lunar primary ejecta environment. The document NASA SP-8013 was developed for the Apollo program and is the latest definition of the primary ejecta environment. There is concern that NASA SP-8013 may over-estimate the lunar primary ejecta environment. NASA's Meteoroid Environment Office (MEO) has initiated several tasks to improve the accuracy of our understanding of the lunar surface primary ejecta environment. This paper reports the results of experiments on projectile impact into pumice targets, simulating lunar regolith. The Ames Vertical Gun Range (AVGR) was used to accelerate spherical Pyrex projectiles of 0.29g to velocities ranging between 2.5 km/s and 5.18 km/s. Impact on the pumice target occurred at normal incidence. The ejected particles were detected by thin aluminum foil targets placed around the pumice target in a 0.5 Torr vacuum. A simplistic technique to characterize the ejected particles was formulated. Improvements to this technique will be discussed for implementation in future tests.

Edwards, David L.↗
NASA NTRS1991

System for determining position of normal shock in supersonic flow

Light from a plurality of light emitting diodes is transmitted through optical cables (12) to a lens system. The lenses (56, 58) expand and collimate the light and project it in a sheet (16) across the supersonic inlet of an aircraft power plant perpendicular to incoming airflow. A normal shock bends a portion of the sheet of light (16). A linear array of a multiplicity of optical fiber ends collects discrete samples of light. The samples are processed and compared to a predetermined profile to determine the shock location.

Iverson, Jr., Donald G.↗
NASA NTRS2008

Intravenous Fluid Mixing in Normal Gravity, Partial Gravity, and Microgravity: Down-Selection of Mixing Methods

The missions envisioned under the Vision for Space Exploration will require development of new methods to handle crew medical care. Medications and intravenous (IV) fluids have been identified as one area needing development. Storing certain medications and solutions as powders or concentrates can both increase the shelf life and reduce the overall mass and volume of medical supplies. The powders or concentrates would then be mixed in an IV bag with Sterile Water for Injection produced in situ from the potable water supply. Fluid handling in microgravity is different than terrestrial settings, and requires special consideration in the design of equipment. This document describes the analyses and down-select activities used to identify the IV mixing method to be developed that is suitable for ISS and exploration missions. The chosen method is compatible with both normal gravity and microgravity, maintains sterility of the solution, and has low mass and power requirements. The method will undergo further development, including reduced gravity aircraft experiments and computations, in order to fully develop the mixing method and associated operational parameters.

Niederhaus, Charles E.↗
NASA NTRS2008

Comparison of Ejecta Distributions from Normal Incident Hypervelocity Impact on Lunar Regolith Simulant

The National Aeronautics and Space Administration (NASA) is progressing toward long-term lunar habitation. Critical to the design of a lunar habitat is an understanding of the lunar surface environment; of specific importance is the primary meteoroid and subsequent ejecta environment. The document, NASA SP-8013, was developed for the Apollo program and is the latest definition of the ejecta environment. There is concern that NASA SP-8013 may over-estimate the lunar ejecta environment. NASA's Meteoroid Environment Office (MEO) has initiated several tasks to improve the accuracy of our understanding of the lunar surface ejecta environment. This paper reports the results of experiments on projectile impact into powered pumice and unconsolidated JSC-1A Lunar Mare Regolith stimulant (JSC-1A) targets. The Ames Vertical Gun Range (AVGR) was used to accelerate projectiles to velocities in excess of 5 km/s and impact the targets at normal incidence. The ejected particles were detected by thin aluminum foil targets placed around the impact site and angular distributions were determined for ejecta. Comparison of ejecta angular distribution with previous works will be presented. A simplistic technique to characterize the ejected particles was formulated and improvements to this technique will be discussed for implementation in future tests.

Edwards, David L.↗
NASA NTRS2004

Analysis of the Variation of Energetic Electron Flux with Respect to Longitude and Distance Normal to the Magnetic Equatorial Plane for Galileo Energetic Particle Detector Data

In this study we examine ten-minute omni-directional averages of energetic electron data measured by the Galileo spacecraft Energetic Particle Detector (EPD). Count rates from electron channels B1, DC2, and DC3 are evaluated using a power law model to yield estimates of the differential electron fluxes from 1 MeV to 11 MeV at distances between 8 and 51 Jupiter radii. Whereas the orbit of the Galileo spacecraft remained close to the rotational equatorial plane of Jupiter, the approximately 11 degree tilt of the magnetic axis of Jupiter relative to its rotational axis allowed the EPD instrument to sample high energy electrons at limited distances normal to the magnetic equatorial plane. We present a Fourier analysis of the semi-diurnal variation of electron fluxes with longitude.

synchrotron radiation↗
NASA NTRS2009

Kinematic and EMG Comparison of Gait in Normal and Microgravity

Astronauts regularly perform treadmill locomotion as a part of their exercise prescription while onboard the International Space Station. Although locomotive exercise has been shown to be beneficial for bone, muscle, and cardiovascular health, astronauts return to Earth after long duration missions with net losses in all three areas [1]. These losses might be partially explained by fundamental differences in locomotive performance between normal gravity (NG) and microgravity (MG) environments. During locomotive exercise in MG, the subject must wear a waist and shoulder harness that is attached to elastomer bungees. The bungees are attached to the treadmill, and provide forces that are intended to replace gravity. However, unlike gravity, which provides a constant force upon all body parts, the bungees provide a spring force only to the harness. Therefore, subjects are subjected to two fundamental differences in MG: 1) forces returning the subject to the treadmill are not constant, and 2) forces are only applied to the axial skeleton at the waist and shoulders. The effectiveness of the exercise may also be affected by the magnitude of the gravity replacement load. Historically, astronauts have difficulty performing treadmill exercise with loads that approach body weight (BW) due to comfort and inherent stiffness in the bungee system. Although locomotion can be executed in MG, the unique requirements could result in performance differences as compared to NG. These differences may help to explain why long term training effects of treadmill exercise may differ from those found in NG. The purpose of this investigation was to compare locomotion in NG and MG to determine if kinematic or muscular activation pattern differences occur between gravitational environments.

DeWitt, John K.↗
NASA NTRS2009

A Comparison Study of Normal-Incidence Acoustic Impedance Measurements of a Perforate Liner

The eduction of the acoustic impedance for liner configurations is fundamental to the reduction of noise from modern jet engines. Ultimately, this property must be measured accurately for use in analytical and numerical propagation models of aircraft engine noise. Thus any standardized measurement techniques must be validated by providing reliable and consistent results for different facilities and sample sizes. This paper compares normal-incidence acoustic impedance measurements using the two-microphone method of ten nominally identical individual liner samples from two facilities, namely 50.8 mm and 25.4 mm square waveguides at NASA Langley Research Center and the University of Florida, respectively. The liner chosen for this investigation is a simple single-degree-of-freedom perforate liner with resonance and anti-resonance frequencies near 1.1 kHz and 2.2 kHz, respectively. The results show that the ten measurements have the most variation around the anti-resonance frequency, where statistically significant differences exist between the averaged results from the two facilities. However, the sample-to-sample variation is comparable in magnitude to the predicted cross-sectional area-dependent cavity dissipation differences between facilities, providing evidence that the size of the present samples does not significantly influence the results away from anti-resonance.

Schultz, Todd↗
NASA NTRS2010

Non-Pyrotechnic Zero-Leak Normally Closed Valve

This valve is designed to create a zero-leak seal in a liquid propulsion system that is a functional replacement for the normally closed pyrovalve. Unlike pyrovalves, Nitinol is actuated by simply heating the material to a certain temperature, called the transition temperature. Like a pyrovalve, before actuation, the upstream and downstream sections are separated from one another and from the external environment by closed welded seals. Also like pyrovalves, after actuation, the propellant or pressurant gas can flow without a significant pressure drop but are still separated from the external environment by a closed welded seal. During manufacture, a Nitinol bar is compressed to 93 percent of its original length and fitted tightly into the valve. During operation, the valve is heated until the Nitinol reaches the transition temperature of 95 C; the Nitinol "remembers" its previous longer shape with a very large recovery force causing it to expand and break the titanium parent metal seal to allow flow. Once open, the valve forever remains open. The first prototype valve was designed for high pressure [5,000 psi (=34.5 MPa)] and low flow, typical requirements for pressurant gas valves in liquid propulsion systems. It is possible to modify the dimensions to make low-pressure models or high-flow models, for use downstream of the propellant tanks. This design is simpler, lower risk, and less expensive than the pyrovalve. Although the valve must be in a thermally controlled state (kept below 80 C) to prevent premature actuation, the pyrovalves and electrically actuated initiators have far more taxing handling requirements.

Gillespie, Rebecca↗
NASA NTRS2010

An Investigation of the Longitudinal Proximity Effect in Superconducting and Normal Metal TES

As the TES volume and (effective) Tc become very small - for volume < 10 micrometers x 10 micrometers x 0.5 micrometers and Tc < 90 mK - we approach a regime in which the noise equivalent power is dominated by fluctuations in power dissipating from the TES electrons to its phonons. Our ultimate goal is to build a TES bolometer that operates in this regime to be used for far-infrared and sub-mm astronomy. In this study, we characterize the R vs T behavior of small TES in order to engineer a TES bolometer that has a very low Tc. Sadleir et al found that as the distance L between two superconducting leads, with the lead Tc >> the TES Tc, connected at opposite ends of TES approaches zero, superconductivity is induced parallel to the current flow, or longitudinally, and results in a much higher effective TES Te. Here we present effective Te measurements of Mo/Au TES bounded by Nb leads as a function of L which ranges between 4 and 36 micrometer. We observe that the effective Te is suppressed for current density of order 10(exp -6) A/sq micrometers. We also explore the possibility of using a normal metal TES.

Brown, Ari-David↗
NASA NTRS2010

Normalized-Difference Snow Index (NDSI)

The Normalized-Difference Snow Index (NDSI) has a long history. 'The use of ratioing visible (VIS) and near-infrared (NIR) or short-wave infrared (SWIR) channels to separate snow and clouds was documented in the literature beginning in the mid-1970s. A considerable amount of work on this subject was conducted at, and published by, the Air Force Geophysics Laboratory (AFGL). The objective of the AFGL work was to discriminate snow cover from cloud cover using an automated algorithm to improve global cloud analyses. Later, automated methods that relied on the VIS/NIR ratio were refined substantially using satellite data In this section we provide a brief history of the use of the NDSI for mapping snow cover.

Hall, Dorothy K.↗
NASA NTRS2012

Experimental Investigation of Normal Shock Boundary-Layer Interaction with Hybrid Flow Control

Hybrid flow control, a combination of micro-ramps and micro-jets, was experimentally investigated in the 15x15 cm Supersonic Wind Tunnel (SWT) at the NASA Glenn Research Center. Full factorial, a design of experiments (DOE) method, was used to develop a test matrix with variables such as inter-ramp spacing, ramp height and chord length, and micro-jet injection flow ratio. A total of 17 configurations were tested with various parameters to meet the DOE criteria. In addition to boundary-layer measurements, oil flow visualization was used to qualitatively understand shock induced flow separation characteristics. The flow visualization showed the normal shock location, size of the separation, path of the downstream moving counter-rotating vortices, and corner flow effects. The results show that hybrid flow control demonstrates promise in reducing the size of shock boundary-layer interactions and resulting flow separation by means of energizing the boundary layer.

Vyas, Manan A.↗
NASA NTRS2012

Near-Nadiral Normalized Radar Cross Section of the SEA Surface at Ku, Ka, and W-Bands: Comparison of Measurements and Models

Understanding the relationship between wind speed and direction and the near-nadiral normalized radar cross section (NRCS) of the sea surface is important in many oceanographic and atmospheric remote sensing applications: (1) wind speed retrievals in traditional altimeter systems (2) assistance in calibration and path integrated attenuation processing for atmospheric profiling radars The desired wind speed (and direction in some cases) retrieval requires a clear understanding of the relationship between the relevant geophysical quantities and the observed NRCS Such understanding is available from existing electromagnetic models, but the presence of many such models, as well as implicit descriptions of the sea surface, motivates continued evaluation of model performance.

CloudSat↗
NASA NTRS2013

3D Normal Human Neural Progenitor Tissue-Like Assemblies: A Model of Persistent VZV Infection

Varicella-zoster virus (VZV) is a neurotropic human alphaherpesvirus that causes varicella upon primary infection, establishes latency in multiple ganglionic neurons, and can reactivate to cause zoster. Live attenuated VZV vaccines are available; however, they can also establish latent infections and reactivate. Studies of VZV latency have been limited to the analyses of human ganglia removed at autopsy, as the virus is strictly a human pathogen. Recently, terminally differentiated human neurons have received much attention as a means to study the interaction between VZV and human neurons; however, the short life-span of these cells in culture has limited their application. Herein, we describe the construction of a model of normal human neural progenitor cells (NHNP) in tissue-like assemblies (TLAs), which can be successfully maintained for at least 180 days in three-dimensional (3D) culture, and exhibit an expression profile similar to that of human trigeminal ganglia. Infection of NHNP TLAs with cell-free VZV resulted in a persistent infection that was maintained for three months, during which the virus genome remained stable. Immediate-early, early and late VZV genes were transcribed, and low-levels of infectious VZV were recurrently detected in the culture supernatant. Our data suggest that NHNP TLAs are an effective system to investigate long-term interactions of VZV with complex assemblies of human neuronal cells.

Goodwin, Thomas J.↗