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Developing High-Throughput Organ-On-A-Chip Models to Investigate the Effects of Ionizing Radiation on the Central Nervous System

One of the main health risks in human space exploration is central nervous system (CNS) damage by ionizing radiation. Irradiation with simulated GCRs or their components, or high doses of low-LET radiation such as gamma rays, in animal models has been shown to cause neuronal damage together with glial cell activation and neuroinflammation and has been associated with prolonged cognitive and behavioral dysfunction. The extent of CNS damage in response to any insult, including ionizing radiation, is partially regulated by the blood-brain barrier (BBB), which enables immune cells to enter the CNS. The main cellular regulators of BBB permeability are astrocytes, which also modulate neuronal death, immune responses and oxidative stress, and thus could serve as a robust CNS-specific target for countermeasure development. However, studies on BBB permeability and astrocyte functions in regulating CNS responses to ionizing radiation have been limited, especially in human tissue/organ analogs. Therefore, we have established a high throughput 3D organ-on-a-chip system to study human CNS functions in response to ionizing radiation, with the eventual goal of adapting it to spaceflight missions. We utilized commercially available OrganoPlate system (Mimetas, Inc.) seeded with primary or induced pluripotent stem cell-derived human cells for developing 3D neuronal-astrocytic and BBB models. We investigated both immediate and delayed CNS dose responses to 0.5-1 Gy X-rays by measuring BBB permeability and morphology, and astrocyte activation. We have also quantified secreted markers of oxidative stress and cell viability. In the future, we are planning to monitor dendritic, axonal and synaptic changes in neurons, evaluate the combined exposures to simulated microgravity and ionizing radiation, and compare the responses to low and high-LET ionizing radiation. We anticipate these studies could indicate novel cellular and mechanistic targets for countermeasure developments to improve CNS functions in astronauts.

Malkani, Sherina↗

Coupled Fluids-Radiation Analysis of a High-Mass Mars Vehicle

The NEQAIR line-by-line radiation code has been incorporated into the DPLR Navier-Stokes flow solver such that the NEQAIR subroutines are now callable functions of DPLR. The coupled DPLR-NEQAIR code was applied to compute the convective and radiative heating rates over high-mass Mars entry vehicles. Two vehicle geometries were considered - a 15 m diameter 70-degree sphere cone configuration and a slender, mid-L/D vehicle with a diameter of 5 m called an Ellipsled. The entry masses ranged from 100 to 165 metric tons. Solutions were generated for entry velocities ranging from 6.5 to 9.1 km/s. The coupled fluids-radiation solutions were performed at the peak heating location along trajectories generated by the Traj trajectory analysis code. The impact of fluids-radiation coupling is a function of the level of radiative heating and the freestream density and velocity. For the high-mass Mars vehicles examined in this study, coupling effects were greatest for entry velocities above 8.5 km/s where the surface radiative heating was reduced by up 17%. Generally speaking, the Ellipsled geometry experiences a lower peak radiative heating rate but a higher peak turbulent convective heating rate than the MSL-based vehicle.

Palmer, Grant↗

An Overview of CMIP5 and CMIP6 Simulated Cloud Ice, Radiation Fields, Surface Wind Stress, Sea Surface Temperatures and Precipitation over Tropical and Subtropical Oceans

The potential links between ice water path (IWP), radiation, circulation, sea surface temperature (SST) and precipitation over the Pacific and Atlantic Oceans resulting from the falling ice radiative effects (FIREs) are examined from present day model outputs of CMIP5 and CMIP6. The latter is divided into two subsets with (SON6) and without FIREs (NOS6) as more models with FIREs are included in CMIP6 than in CMIP5. Improvement in floating cloud ice (~20 g m-2) is noticeable over convective regions in CMIP6 relative to CMIP5. The inclusion of FIREs in SON6 subset may contribute to reduce biases of overestimated outgoing longwave radiation and downward surface shortwave and overestimated reflected shortwave at the top of the atmosphere (TOA) by magnitudes of 4?8 W m-2 over convective regions against CERES, compared to NOS6 subset. The reduced biases in radiative fluxes in convective regions stabilize the atmosphere and lead to circulation, SST, cloud and precipitation changes over the trade-wind regions, as seen from improved radiative fluxes (4?15 W m-2), surface wind stress biases, SST (0.2?0.8 K) and precipitation (1 mm day-1) biases. The significant improvement from NOS6 to SON6 leads to improved multi-model means for CMIP6 relative to CMIP5 for radiation fields over the trade wind regions but the degradation over convective zones is attributed to NOS6 subset. The results suggest that other sources of uncertainty and deficiencies in climate models may play significant roles for reducing discrepancies although FIREs, via radiation-circulation coupling, may be one of the factors that help to reduce regional biases.

Jui-Lin F Li↗

Uncertainty in Observational Estimates of the Aerosol Direct Radiative Effect and Forcing

Aerosols continue to be responsible for the largest uncertainty in determining the anthropogenic radiative forcing of the climate. To both reconcile the large range in satellite-based estimates of the aerosol direct radiative effect (DRE, the direct interaction with solar radiation by all aerosols) and to optimize the design of future observing systems, we build a framework for assessing uncertainty in aerosol DRE and the aerosol direct radiative forcing (DRF, the radiative effect of just anthropogenic aerosols, RF_ari). Shortwave aerosol radiative kernels (Jacobians) were derived using the MERRA-2 reanalysis data. These radiative kernels are used to compute a lower-bound on the systematic uncertainty in observational estimates of the aerosol DRE/DRF by making the optimistic assumption that global aerosol observations can be made with the accuracy found in the Aerosol Robotic Network (AERONET) sun photometer retrievals. The total uncertainty is shown to be dominated by contributions from the aerosol single scattering albedo uncertainty. These uncertainty estimates were compared to a literature survey of mostly satellite-based aerosol DRE/DRF values. Comparisons to previous studies reveal that most have significantly underestimated the aerosol DRE uncertainty. Past estimates of the aerosol DRF uncertainty are smaller (on average) than our optimistic observational estimates, including the aerosol DRF uncertainty given in the Intergovernmental Panel on Climate Change (IPCC) fifth assessment report (AR5).

Tyler James Thorsen↗

Uncertainty in Observational Estimates of the Aerosol Direct Radiative Effect and Forcing

Aerosols continue to be responsible for the largest uncertainty in determining the anthropogenic radiative forcing of the climate. To both reconcile the large range in satellite-based estimates of the aerosol direct radiative effect (DRE, the direct interaction with solar radiation by all aerosols) and to optimize the design of future observing systems, we build a framework for assessing uncertainty in aerosol DRE and the aerosol direct radiative forcing (DRF, the radiative effect of just anthropogenic aerosols, RF_ari). Shortwave aerosol radiative kernels (Jacobians) were derived using the MERRA-2 reanalysis data. These radiative kernels are used to compute a lower-bound on the systematic uncertainty in observational estimates of the aerosol DRE/DRF by making the optimistic assumption that global aerosol observations can be made with the accuracy found in the Aerosol Robotic Network (AERONET) sun photometer retrievals. The total uncertainty is shown to be dominated by contributions from the aerosol single scattering albedo uncertainty. These uncertainty estimates were compared to a literature survey of mostly satellite-based aerosol DRE/DRF values. Comparisons to previous studies reveal that most have significantly underestimated the aerosol DRE uncertainty. Past estimates of the aerosol DRF uncertainty are smaller (on average) than our optimistic observational estimates, including the aerosol DRF uncertainty given in the Intergovernmental Panel on Climate Change (IPCC) fifth assessment report (AR5).

Tyler James Thorsen↗

Thermal Radiator for CO2 Deposition in Deep Space Transit (FY21 XHab Final Report - University of North Texas)

This UNT Senior design team was tasked by NASA to develop a variable conductance thermal radiator prototype for CO2 deposition for deep space transit. NASA selects university teams every year to partake in the X-HAB Academic Innovation Challenge, with this year’s number of teams being six. Air Revitalization is a crucial system for any space travel, be it for Low Earth Orbit, such as the International Space Station, or for deep space transit. Current systems, such as the Carbon Dioxide Removal Apparatus aboard the ISS, require upkeep and maintenance, which cannot be done on long distance space missions. For the past several years, NASA has done research on Cryogenic systems for Carbon Dioxide removal. These systems operate on the fact that Carbon Dioxide freezes at a higher temperature than Oxygen and Nitrogen, so Carbon Dioxide can be frozen out of the cabin atmosphere without the use of filters, which degrade over time. To cool the cabin air down to a temperature where Carbon Dioxide freezes, Stirling cryocoolers have been used, which have shown promise in the hope of Carbon Dioxide deposition for Cabin Air Revitalization. Cryogenic systems are much more reliable but require significant energy input to operate. Physical systems, such as radiators, have generally not been used for this task, as there is a need to be able to “turn off” the rejection of heat to allow the frozen carbon dioxide to be collected. However, with working fluids pumped through a physical radiator, that aspect of operation can be achieved. The goal of this challenge is to determine the effectiveness of a variable conductance thermal radiator that can reject heat to deep space, without the use of a dedicated cryocooler to remove energy from the cabin air. The proposed design uses piping, hot and cold working fluids, and non-condensable gas to absorbl heat from the cabin air on one side of the radiator and reject the heat to deep space by means of thermal radiation. As well, the system will allow for the recovery of deposited Carbon Dioxide. The UNT X-HAB 2021 team will create a model radiator and test its performance with simulated heat sources and sinks and extrapolate those data points to analyze for real world conditions.

Travis Seaver↗

Chimeric Mouse Models for Space Radiation Risk Investigations

Assessment of human health risks associated with space radiation exposure is based largely on the knowledge learned from studies in which animals, mostly rodents, are exposed to high-LET radiation on the ground. It has been recognized that translation of animal results to meaningful implications for human disease can be challenging, particularly for certain risk categories such as the high-LET radiation effects in the central nervous system (CNS). Considering limitations in utilizing non-human primates and clinical studies in humans, chimeric animals can potentially bridge the knowledge gap between rodents and humans. In a chimeric animal, a specific organ or a cell type is replaced with respective human cells that are functional. A number of chimeric mouse models have been developed in the medical research community to study human diseases, and some of the models can potentially be used for NASA applications. For instance, mice engrafted with human hepatocytes, which have been used in studies of genotoxicity from carcinogen exposures, can be used for quantification of space radiation damage. A chimeric brain model, which was shown to perform superiorly in memory and cognitive tests, can also be a candidate for studying the CNS effects of radiation. It has also been reported that mice engrafted with human hematopoietic progenitor cells were exposed to X-rays and high-LET Si ions to investigate the radiation effects in the immune system. In a pilot study, we use PXB mice whose livers contain >90% human cells. These mice are exposed to gamma rays for investigations of DNA damage and transcriptomics changes in the humanized livers. Results obtained from PXB mice will be compared non-engrafted control animals from the same background strain that are exposed to identical conditions. The aim of the study is to determine whether chimeric mouse models are suitable for investigations of space radiation risks.

Honglu Wu↗

Chimeric Mouse Models for Space Radiation Risk Investigations

Assessment of human health risks associated with space radiation exposure is based largely on the knowledge learned from studies in which animals, mostly rodents, are exposed to high-LET radiation on the ground. It has been recognized that translation of animal results to meaningful implications for human disease can be challenging, particularly for certain risk categories such as the high-LET radiation effects in the central nervous system (CNS). Considering limitations in utilizing non-human primates and clinical studies in humans, chimeric animals can potentially bridge the knowledge gap between rodents and humans. In a chimeric animal, a specific organ or a cell type is replaced with respective human cells that are functional. A number of chimeric mouse models have been developed in the medical research community to study human diseases, and some of the models can potentially be used for NASA applications. For instance, mice engrafted with human hepatocytes, which have been used in studies of genotoxicity from carcinogen exposures, can be used for quantification of space radiation damage. A chimeric brain model, which was shown to perform superiorly in memory and cognitive tests, can also be a candidate for studying the CNS effects of radiation. It has also been reported that mice engrafted with human hematopoietic progenitor cells were exposed to X-rays and high-LET Si ions to investigate the radiation effects in the immune system. In a pilot study, we use PXB mice whose livers contain >90% human cells. These mice are exposed to gamma rays for investigations of DNA damage and transcriptomics changes in the humanized livers. Results obtained from PXB mice will be compared non-engrafted control animals from the same background strain that are exposed to identical conditions. The aim of the study is to determine whether chimeric mouse models are suitable for investigations of space radiation risks.

Honglu Wu↗

Mechanically Tunable Radiative Cooling for Adaptive Thermal Control

Passive radiative cooling is currently thefrontier technology in renewable-energy research. Interms of extraterrestrial applications, radiative cooling is a critical component to the thermalmanagement system of a spacecraft, where the extreme environment of space can cause largetemperature variations that can break and damage equipment. For terrestrial applications,nocturnal or daytime radiative cooling is expected to lead to cost-effective passive heatmanagement without the need of inefficient and costly artificial refrigeration technologies.However, most currently available radiative cooling systems cannot be changed dynamically andradiate a constant static amount of thermal power. Dynamically tunable adaptive radiativecooling systems will be a critical development to prolong the lifetime of spacecraft or improvethe efficiency of terrestrial cooling systems. Here we propose stretchable radiative coolingdesigns that can be substantially tuned by using the simple physical mechanism of mechanical strain. When their structure is stretched, the radiated power is significantly reduced. We developa modeling method that can simulate mechanical stretching combined with electromagnetic response to compute the tunable thermal emission of these new adaptive radiative coolingsystems. The presented photonically engineered structures can be used as coatings to achieveefficient adaptive thermal control of various objects in a cost-effective and environmentallyfriendly way. The proposed designs are much simpler to be realized than others found in theliterature and the best design achieves a high thermal emission power with a tunable range on theorder of 132 W/m2.

Andrew Butler↗

MARS 2020 Backshell Radiative Heating Measurement and Shock Tube Verification

In February 2021, the Perseverance rover was brought to the surface of Mars by the Mars 2020 mission. A feature of the Mars 2020 capsule was instrumentation to measure its entry, descent and landing (EDL) with the so-called Mars EDL Instrumentation 2 (MEDLI2) [1]. The MEDLI2 introduced, among other things, backshell instrumentation, including a broadband radiometer. The radiometer was mounted on the leeside of the vehicle next to thermocouple plugs and a heat flux gauge. The data returned by the leeside MEDLI2 heat flux gauge is largely analogous to that measured by the COMARS gauge flown on the ExoMars Schiaparelli [2] entry in that it is measuring heat flux in an area that is entirely dominated by radiative heating. The COMARS measurement provided excellent validation of backshell radiative heating models for Mars entry, albeit at a limited number of points [3]. The MEDLI2 heat flux gauge measurement effectively confirmed the quality of the prediction, extended over the full trajectory, as will be presented in this paper. The MEDLI2 radiometer,however, was blocked by ablation products and suffered a loss of half of its signal. The second backshell heat flux gauge installed on the windside of the vehicle was also well predicted, although the heating had both radiative and convective contributions. It was desired to reproduce the conditions of the Mars 2020 entry via ground testing in the Electric Arc Shock Tube (EAST) at NASA Ames. Tests to verify stagnation line heating were previously reported in EAST, confirming the presence of shock layer radiation as the major discrepancy in heatshield temperature modelling [4]. Therefore, tests for stagnation line heating were not repeated. Instead, the shock tube informed bias method [5, 6] was used to identify test conditions that may produce similarity to streamlines that pass around the backside of the vehicle and are responsible for the radiation observed at the two heat flux gauge locations. This method was used to identify a range of velocities and densities in the shock tube that are relevant for confirming the radiative environment encountered. This paper reports the results obtained in the 10 cm diameter EAST shock tube, corresponding to later trajectory points at ambient pressures of 1.1-2.0 Torr and velocities from 1.2-3.5 km/s. The test series employed two primary diagnostics: emission spectroscopy and tunable diode laser absorption spectroscopy (TDLAS). The emission spectroscopy performed broadband measurements of the radiative emission of the 4.3 and 2.7 m bands of CO2 at flight similar conditions, obtaining both spectral and spatial data corresponding to the relaxation behind the shock front. The TDLAS measured the absorption of several lines of CO and CO2 and obtains species number densities and temperatures as a function of time behind the shock front. This paper will review highlights of this test series and analyses of the emission and absorption data. While the datasets generally show good agreement with predictions, a few discrepancies and items for additional investigation are identified and will be discussed

Brett A Cruden↗

Outcomes of a Mini Technical Interchange Meeting Concerning the Risk of Cardiovascular Disease from Exposure to Space Radiation

The NASA Human Research Program’s (HRP) Space Radiation Element (SRE) funds research to characterize and mitigate adverse health outcomes from exposure to space radiation to enable deep space exploration and sustained human presence in space. Damage to the cardiovascular system has been observed after exposure to clinically relevant doses of ionizing radiation. However, an association between lower radiation doses and cardiovascular disease (CVD) remains controversial, and questions pertaining to dose thresholds, radiation quality and dose-rate effects, and gaps in characterizing the mechanisms and major pathways of CVD remain. To solicit new ideas for characterizing and mitigating this risk, the SRE is organizing a series of miniature technical interchange meeting (Tiny-TIM) that provide a venue for HRP-funded investigators and thought leaders to present ongoing work and engage in open discussion on relevant topics. The initial Tiny-TIM: Upping the Ante on Characterizing and Mitigating Cardiovascular Disease Risk from Space Radiation Exposure, held at the NASA HRP Investigators’ Workshop (IWS) earlier this year, consisted of two 90-minute sessions; the first focused on current knowledge of CVD risk from space radiation exposure, and the second focused on innovative ideas, and newer approaches and techniques to accelerate research. The second session was followed by an open, spirited discussion amongst peers on the current issues impeding the characterization of CVD risk. SRE leadership facilitated the discussion using a set of pressing questions and gaps in knowledge that need to be addressed by the scientific community. This poster presents the outcomes of the Tiny-TIM, along with proposed future workshops and the SRE’s other initiatives.

Janapriya Saha↗

The Potential Effects of Radiation on the Gut-Brain Axis

Humans may be exposed to different types of radiation in their lifetimes, typically in the form of low linear energy transfer (LET) radiation that is, for example, used as a treatment for cancer. In addition, astronauts may be exposed to high LET radiation in outer space. Here, we propose that alterations to the gastrointestinal (GI) microbiota may occur upon exposure to low or high LET radiation, and that these alterations may perturb important relationships that exist between the GI microbiota and human health. For example, the GI microbiota can communicate with the brain via various pathways and molecules, such as the enteric nervous system, the vagus nerve, microbial metabolites, and the immune system. This relationship has been termed the “gut-brain axis”. Alterations to the composition of the GI microbiome can lead to alterations in its functional metabolic output and means of communication, therefore potentially causing downstream cognitive effects. Consequently, studying how radiation can affect this important network of communication could lead to new and critical interventions, as well as prevention strategies. Herein, we review the evidence supporting a relationship between radiation exposure and disruption of the gut-brain axis as well as summarize strategies that may be used to counter the effects of radiation exposure on the GI microbiome.

Carli B. Jones↗

Towards a More Realistic Representation of NASA CERES-derived Surface Radiative Fluxes during Polar Night: A Comparison with the MOSAiC Field Campaign

The Arctic remains one of the more difficult regions observe, and so satellite observations are a critical tool for observing the region, such as those from Clouds and the Earth’s Radiant Energy System (CERES). But validating the satellite surface radiative flux estimates is difficult because of the lack of in situ measurements. The extensive high-quality surface radiative flux and meteorological measurements collected from MOSAiC provide a useful check on flux retrievals from CERES instruments. We compare MOSAiC and CERES surface radiative fluxes during October through March of 2019-2020 using the large set of meteorological measurements also collected by MOSAiC, specifically cloud properties. Previous work identified a significant source of error in the CERES estimate of surface downwelling longwave flux as the estimate of low level cloud amount when compared with MOSAiC W-band radar measurements. Continuing this work, we examine the effects of errors in cloud water path on surface radiative fluxes. When using all cloud conditions, errors in cloud water are also significantly correlated with surface radiative flux errors, though the size off the effect is only about half that of cloud amount. But when considering low cloud conditions only, the effects of cloud water and cloud amount are comparable. We compare MOSAiC and CERES surface radiative fluxes during October through March of 2019-2020 using the large set of meteorological measurements also collected by MOSAiC, specifically cloud properties. Previous work identified a significant source of error in the CERES estimate of surface downwelling longwave flux as the estimate of low level cloud amount when compared with MOSAiC W-band radar measurements. We further examine this source of error by examining selected case studies in which the disagreements in radiative fluxes and clouds are large.

J Brant Dodson↗

Comparison of the Nowcast of Aerospace Ionizing Radiation System (NAIRAS) With ISS Measurements

The Nowcast of Aerospace Ionizing Radiation System (NAIRAS) is a sophisticated physics-based model that has been providing real-time global predictions of cosmic radiation exposure, pertinent to both galactic and solar sources, to air travelers for a decade. The utility of NAIRAS, however, extends beyond the atmospheric ionizing radiation environment. The recently developed NAIRAS 3.0 version demonstrates an expansion of its domain to the space radiation environment. This extension incorporates an additional trapped inner belt proton source, coupled with altitude-dependent and rigidity-dependent geomagnetic shielding for galactic cosmic rays (GCR) and solar energetic particle (SEP) protons. The latest version of NAIRAS operates in two modes: real-time global predictions of the atmospheric radiation environment and a user-specified run-on-request service for global dosimetric calculations or predictions of dosimetric and particle flux quantities along user-uploaded flight path. It is available to the public at the Community Coordinated Modeling Center (CCMC). In this work, we present the validation exercises that have been conducted using the Automated Radiation Measurements for Aerospace Safety (ARMAS) onboard the International Space Station (ISS), thereby establishing NAIRAS's efficacy in predicting space radiation exposure. As such, NAIRAS 3.0 holds significant potential for human safety and technological advancement in aerospace travel and exploration.

Daniel Phoenix↗

A Machine Learning Approach to Determine Surface Radiative Fluxes based on CERES Observations

The Clouds and Earth’s Radiant Energy System (CERES) projects provides satellite-based observations of the radiative fluxes and clouds systems. CERES climate quality data products typically take several months of calibration and validation before release to the public. An alternative data product, Fast Longwave and Shortwave radiative Flux (FLASHFlux), was created to provide data to the applied sciences and educational users. FLASHFlux provides Top-of-Atmosphere radiative fluxes, Clouds properties, and parameterized surface radiative fluxes within four days for footprint (Level 2) data. We investigate the use of Artificial Neural Network (ANN) using MODerate resolution Imaging Spectroradiometer (MODIS) derived clouds properties and meteorology from the Global Assimilation and Meteorology Office (GMAO) scaled to the CERES footprint from the CERES Clouds Radiative Swath (CRS) data product to compute surface radiative fluxes. We test ANN produce fluxes against surface fluxes produced from the Fu-Liou model used in CRS and the Langley Parameterized Shortwave Algorithm (LPSA) and Langley Parameterized Longwave Algorithm (LPLA) used in FLASHFlux. We also validated each model with ground-based observations. Furthermore, we investigate Leave-One-Feature-Out Importance (LOFO) to evaluate the significance of each feature in our training and provide insight for future models. Advances in machine learning, along with increases in computational capabilities and available data allow us to estimate effects of unresolved processes in our climate without direct modeling. This work evaluates the ability to create accurate data-driven models to supplement or replace current models that estimate surface radiative fluxes.

Climatology↗

Electrodynamic Dust Shield for Active Dust Mitigation of Thermal Radiators

This project sought to investigate whether the Electrodynamic Dust Shield (EDS) would work with various thermal control coatings (TCC) to remove dust off the TCC. Keeping surfaces dust free is essential for thermal radiators as the dust acts as both a blackbody and a thermal insulator so it will absorb more sunlight and prevent the radiator from radiating heat. The lack of heat rejection on dusty surfaces causes the radiator to be oversized and potentially cause catastrophic system failure due to overheating. With an EDS integrated into the radiator system, dust impacts can be mitigated by removing the dust off the surface using electric fields. This project tested dust removal, solar absorptance, emittance, and limited thermal vacuum with a TCC on an EDS which is bonded to an aluminum plate acting like a radiator. The results of various coatings suggests that the EDS can work with insulative TCC in high vacuum for removing dust, and that after removing dust, the solar absorptance can be restored to within 5-10% of its original value when the EDS works properly. More work is necessary to determine how the EDS impacts the emittance of the whole radiator system and bonding between the different layers needs to be investigated to withstand temperature cycling of the moon without delamination occurring.

Krystal Acosta↗

Arctic Radiation-Cloud-Aerosol-Surface Interaction eXperiment (ARCSIX)

The Arctic climate system is amidst a transition. Over the last 40 years, the Arctic sea ice pack has transformed from a predominantly thick, multi-year sea ice to a predominantly thin, seasonal sea ice, termed the “New Arctic”. The observed rapid changes in the Arctic sea ice pack are an integral part of the Arctic Amplification phenomenon and represent a response to and a feedback on global climate change. As a result, the role of the Arctic within the global climate system is changing. Substantial uncertainty exists in our understanding of the atmosphere-surface interactions within the Arctic system, limiting our knowledge of the Arctic’s role in the future climate. Advancing our understanding of the Arctic climate system requires (1) measurements of the coupling between radiative processes and sea ice surface properties during summer sea ice melt; (2) measurements of the processes controlling the predominant Arctic cloud regimes and their properties (Fig. 1); and (3) improvements in the ability to monitor Arctic cloud, radiation, and sea ice processes from space. A key challenge is that thin, low clouds that are radiatively important to the Arctic surface energy budget can go undetected (Fig. 1). The Arctic Radiation-Cloud-Aerosol-Surface-Interaction eXperiment (ARCSIX) is an airborne campaign based at the Pituffik Space Base in Greenland from May-August 2024 sponsored by the National Aeronautics and Space Administration (NASA) to address these needs. ARCSIX consists of two airborne measurement campaigns taking place in two 3-week intervals during the early and late sea ice melt season: late May through early June and late July through early August, respectively. ARCSIX science is guided by three broad science questions that encapsulate the key influences of radiation-cloud-aerosol-sea ice coupling and a remote sensing and modeling objective: Science Question 1 (Radiation): What is the impact of the predominant summer Arctic cloud types on the radiative surface energy budget? Science Question 2 (Cloud Life Cycle): What processes control the evolution and maintenance of the predominant cloud regimes in the summertime Arctic? Science Question 3 (Sea Ice): How do the two-way interactions between surface properties and atmospheric forcings affect the sea ice evolution? Remote Sensing and Modeling Objective: Enhance our long-term space-based monitoring and predictive capabilities of Arctic sea ice, clouds, and aerosols.

Patrick Taylor↗

Uncertainties in an Observation-Based Estimate of the Global Aerosol Direct Radiative Effect

Aerosols impact Earth’s radiation budget directly through interactions with radiation and indirectly via interactions with clouds. Aerosols have significant radiative impacts on Earth’s energy budget and represent the largest uncertainty in the radiative forcing of the current climate. Although the magnitude of the aerosol direct radiative effect (DRE) is estimated to be less than that of the indirect effect, uncertainties are large. While model-based estimates of aerosol radiative forcing are subject to uncertainties in modeled aerosol properties and uncertainties in simulated cloud cover and albedo, most observation-based studies of global aerosol DRE have their own difficulties with aerosol optical properties and have been limited to cloud-free skies in most cases. Estimates of the uncertainty of the aerosol DRE are themselves uncertain and have varied widely among different published studies. In this study we use the CERES-CALIPSO-CloudSat-MODIS (C3M) product to estimate the global clear-sky and all-sky aerosol DRE. C3M merges collocated data from CERES, CALIPSO, CloudSat, and MODIS with information from reanalysis and an aerosol transport model. With CALIOP observations of aerosol below optically thin clouds and above clouds, co-located with cloud albedo from MODIS, the C3M dataset allows a detailed exploration of observational uncertainties. By perturbing the aerosol properties used and comparing radiative effects in perturbed cases with the base case we characterize uncertainties in estimated aerosol DRE due to uncertainties in the aerosol properties involved. The results also provide a basis for determining measurement requirements to improve the accuracy of DRE estimates. We will describe the approach and present results.

Dave Winker↗