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At least 1,009 records · Page 56

Corn Storage Protein - A Molecular Genetic Model

Corn is the highest yielding crop on earth and probably the most valuable agricultural product of the United States. Because it converts sun energy through photosynthesis into starch and proteins, we addressed energy savings by focusing on protein quality. People and animals require essential amino acids derived from the digestion of proteins. If proteins are relatively low in certain essential amino acids, the crop becomes nutritionally defective and has to be supplemented. Such deficiency affects meat and fish production and countries where corn is a staple. Because corn seed proteins have relatively low levels of lysine and methionine, a diet has to be supplemented with soybeans for the missing lysine and with chemically synthesized methionine. We therefore have studied genes expressed during maize seed development and their chromosomal organization. A critical technical requirement for the understanding of the molecular structure of genes and their positional information was DNA sequencing. Because of the length of sequences, DNA sequencing methods themselves were insufficient for this type of analysis. We therefore developed the so-called “DNA shotgun sequencing” strategy, where overlapping DNA fragments were sequenced in parallel and used to reconstruct large DNA molecules via overlaps. Our publications became the most frequently cited ones during the decade of 1981-1990 and former Associate Director of Science for the Office of Basic Energy Sciences Patricia M. Dehmer presented our work as one of the great successes of this program. A major component of the sequencing strategy was the development of bacterial strains and vectors, which were also used to develop the first biotechnology crops. These crops possessed new traits thanks to the expression of foreign genes in plants. To enable such expression, chimeric genes had to be constructed using our materials and methods by the industry. Because we made our materials and methods freely available to academia and industry, progress in plant research and new crop development could accelerate and benefit the public.

60 APPLIED LIFE SCIENCES↗

Mobile Biometric Device (MBD) Technology

Mobile biometric devices (MBDs) capable of both enrolling individuals in databases and performing identification checks of subjects in the field are seen as an important capability for military, law enforcement, and homeland security operations. The technology is advancing rapidly. The Department of Homeland Security Science and Technology Directorate through an Interagency Agreement with Sandia sponsored a series of pilot projects to obtain information for the first responder law enforcement community on further identification of requirements for mobile biometric device technology. Working with 62 different jurisdictions, including components of the Department of Homeland Security, Sandia delivered a series of reports on user operation of state-of-the-art mobile biometric devices. These reports included feedback information on MBD usage in both operational and exercise scenarios. The findings and conclusions of the project address both the limitations and possibilities of MBD technology to improve operations. Evidence of these possibilities can be found in the adoption of this technology by many agencies today and the cooperation of several law enforcement agencies in both participating in the pilot efforts and sharing of information about their own experiences in efforts undertaken separately.

Aldridge, Chris D.↗

Alternate Funding Sources for the International Atomic Energy Agency

Since 1957, the International Atomic Energy Agency (IAEA) has worked to ensure the safe and responsible promotion of nuclear technology throughout the world. The IAEA operates at the intersection of the Nuclear Nonproliferation Treaty’s (NPT) fourth and third articles, which guarantee Parties to the Treaty the right to peaceful uses of nuclear technology, provided those activities are placed under safeguards verified by the IAEA. However, while the IAEA has enjoyed substantial success and prestige in the international community, there is a concern that its resources are being stretched to a point where it may no longer be possible to execute its multifaceted mission in its entirety. As noted by the Director General (DG) in 2008, demographics suggest that every aspect of the IAEA’s operations will be in higher demand due to increasing reliance on non-carbon-based energy and the concomitant nonproliferation, safety, and security risks that growth entails. In addition to these nuclear energy concerns, the demand for technical developmental assistance in the fields of food security, resource conservation, and human health is also predicted to increase as the rest of the world develops. Even with a 100% value-for-money rating by the U.S. Office of Management and Budget (OMB) and being described as an “extraordinary bargain” by the United Nations Secretary-General’s High-level Panel on Threats, Challenges and Change, real budget growth at the Agency has been limited to zero-real growth for a better part of the last two decades. Although the 2012 regular budget (RB) received a small increase for most programs, the 2013 RB has been set at zero-real growth. As a result, the IAEA has had to defer infrastructure investments, which has hindered its ability to provide the public goods its Members seek, decreased global security and development opportunities, and functionally transformed the IAEA into a charity, dependent on extrabudgetary (EB) contributions to sustain its mission and capabilities. To resolve these resource constraints, we recommend the creation of an endowment, funded entirely through private contributions. Our initial estimates for the endowment are that a €2B principal. This level of capitalization could provide significant support to all aspects of the IAEA’s mission, including Capital Investment and Innovation; Technical Cooperation; as well as incentivizing the policy and technology entrepreneurship that will be necessary for the future health of the nonproliferation regime. Given this potential, our future efforts will focus on a more rigorous assessment of the financial requirements, while simultaneously creating the beginnings of a functional organization. These include: organizational structure, metrics for grant-making and performance evaluation, and outreach and fundraising strategies. At the end of this process, there should be sufficient information and engagement to begin to operationalize the endowment through external funding sources.

Toomey, Christopher M.↗

2013 LLNL Nuclear Forensics Summer Program

The Lawrence Livermore National Laboratory (LLNL) Nuclear Forensics Summer Program is designed to give both undergraduate and graduate students an opportunity to come to LLNL for 8–10 weeks for a hands-on research experience. Students conduct research under the supervision of a staff scientist, attend a weekly lecture series, interact with other students, and present their work in poster format at the end of the program. Students also have the opportunity to meet staff scientists one-on-one, participate in LLNL facility tours (e.g., the National Ignition Facility and Center for Accelerator Mass Spectrometry) to gain a better understanding of the multi-disciplinary, on going science at LLNL. Currently called the Nuclear Forensics Summer Program, this program began 13 years ago as the Actinide Sciences Summer Program. The program is run within the Glenn T. Seaborg Institute in the Physical and Life Sciences Directorate at LLNL. The goal of the Nuclear Forensics Summer Program is to facilitate the training of the next generation of nuclear scientists and engineers to solve critical national security problems in the field of nuclear forensics and have the student experience conducting research at the Lab. We select students who are majoring in physics, chemistry, geology, mathematics, nuclear engineering, chemical engineering and environmental sciences. Students engage in research projects in the disciplines of actinide chemistry, radiochemistry, isotopic analysis, computational analysis, radiation detection, and nuclear engineering in order to strengthen the “pipeline” for future scientific disciplines critical to DHS (DNDO), NNSA.

38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEA↗

Without Testing: Stockpile Stewardship in the Second Nuclear Age

Stockpile stewardship is a topic dear to my heart. I’ve been fascinated by it, and I’ve lived it—mostly on the technical side but also on the policy side from 2009 to 2010 at Stanford University as a visiting scholar and the inaugural William J. Perry Fellow. At Stanford I worked with Perry, former secretary of defense, and Sig Hecker, former Los Alamos Lab director (1986–1997), looking at nuclear deterrence, nuclear policy, and stockpile stewardship and at where all this was headed.

45 MILITARY TECHNOLOGY, WEAPONRY, AND NATIONAL DEF↗

Harnessing Light: Capitalizing on Optical Science Trends and Challenges for Future Research (Final Technical Report)

The committee has during the earlier period finalized their work on the report, Optics and Photonics: Essential Technologies for Our Nation (2013). The report did undergo review and initial editorial processing. The NRC released a pre-publication report on August 13, 2012. A final report is now available. The study director has been able to practice his skills in running a national academies committee. From a research perspective the grant has generated a report with recommendations to the government. The work itself is the meetings where the committee convened to hear presenters and to discuss the status of optics and photonics as well as writing the report.

36 MATERIALS SCIENCE↗

Evolution of an interfacial crack on the concrete-embankment boundary

Failure of a dam can have subtle beginnings. A small crack or dislocation at the interface of the concrete dam and the surrounding embankment soil initiated by, for example, a seismic or an explosive event can lead to a catastrophic failure of the dam. The dam may ‘self-rehabilitate’ if a properly designed granular filter is engineered around the embankment. Currently, the design criteria for such filters have only been based on experimental studies. We demonstrate the numerical prediction of filter effectiveness at the soil grain scale. This joint LLNL-ERDC basic research project, funded by the Department of Homeland Security’s Science and Technology Directorate (DHS S&T), consists of validating advanced high performance computer simulations of soil erosion and transport of grain- and dam-scale models to detailed centrifuge and soil erosion tests. Validated computer predictions highlight that a resilient filter is consistent with the current design specifications for dam filters. These predictive simulations, unlike the design specifications, can be used to assess filter success or failure under different soil or loading conditions and can lead to meaningful estimates of the timing and nature of full-scale dam failure.

58 GEOSCIENCES↗

Proceedings of RIKEN BNL Research Center Workshop

The twelfth evaluation of the RIKEN BNL Research Center (RBRC) took place on November 6 – 8, 2012 at Brookhaven National Laboratory. The members of the Scientific Review Committee (SRC), present at the meeting, were: Prof. Wit Busza, Prof. Miklos Gyulassy, Prof. Kenichi Imai, Prof. Richard Milner (Chair), Prof. Alfred Mueller, Prof. Charles Young Prescott, and Prof. Akira Ukawa. We are pleased that Dr. Hideto En’yo, the Director of the Nishina Institute of RIKEN, Japan, participated in this meeting both in informing the committee of the activities of the RIKEN Nishina Center for Accelerator- Based Science and the role of RBRC and as an observer of this review. In order to illustrate the breadth and scope of the RBRC program, each member of the Center made a presentation on his/her research efforts. This encompassed three major areas of investigation: theoretical, experimental and computational physics. In addition, the committee met privately with the fellows and postdocs to ascertain their opinions and concerns. Although the main purpose of this review is a report to RIKEN management on the health, scientific value, management and future prospects of the Center, the RBRC management felt that a compendium of the scientific presentations are of sufficient quality and interest that they warrant a wider distribution. Therefore we have made this compilation and present it to the community for its information and enlightenment.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Global Security Program Management Plan

The Global Security Directorate mission is to protect against proliferant and unconventional nuclear threats –regardless of origin - and emerging new threats. This mission is accomplished as the Los Alamos National Laboratory staff completes projects for our numerous sponsors. The purpose of this Program Management Plan is to establish and clearly describe the GS program management requirements including instructions that are essential for the successful management of projects in accordance with our sponsor requirements. The detailed information provided in this document applies to all LANL staff and their subcontractors that are performing GS portfolio work. GS management is committed to a culture that ensures effective planning, execution, and achievement of measurable results in accordance with the GS mission. Outcomes of such a culture result in better communication, delegated authority, accountability, and increased emphasis on safely and securely achieving GS objectives.

99 GENERAL AND MISCELLANEOUS↗

Proceedings of RIKEN/RBRC Workshop: Scientific Review Committee Meeting: October 30 - November 1, 2013 (Final Report) [Slides]

The thirteenth scientific evaluation of the RIKEN BNL Research Center (RBRC) took place at the Physics Building #510 at Brookhaven National Laboratory. The members of the Scientific Review Committee (SRC), present at the meeting, were: Prof. Sinya Aoki, Prof. Peter Braun-Munzinger, Prof. Kenichi Imai, Prof. Tetsuo Matsui, Prof. Richard Milner (Chair), Prof. Alfred Mueller, Prof. Charles Young Prescott, and Prof. Akira Ukawa. We are pleased that Dr. Hideto En’yo, the Director of the Nishina Institute of RIKEN, Japan, participated in this meeting both in informing the committee of the activities of the RIKEN Nishina Center for Accelerator-Based Science and the role of RBRC and as an observer of this review. In order to illustrate the breadth and scope of the RBRC program, each member of the Center made a presentation on his/her research efforts. This encompassed three major areas of investigation: theoretical, experimental and computational physics. In addition, the committee met privately with the fellows and postdocs to ascertain their opinions and concerns. Although the main purpose of this review is a report to RIKEN management on the health, scientific value, management and future prospects of the Center, the RBRC management felt that a compendium of the scientific presentations are of sufficient quality and interest that they warrant a wider distribution. Therefore we have made this compilation and present it to the community for its information and enlightenment. We thank Brookhaven National Laboratory and the U.S. Department of Energy* for providing the facilities to hold this meeting.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Transportation Electrification Education Partnership for Green Jobs and Sustainable Mobility

This collaborative educational project between the University of Michigan—Ann Arbor, University of Michigan—Dearborn and the Kettering University successfully executed almost all the elements we proposed to do. In the original proposal, we proposed to develop four graduate courses, six undergraduate courses, four professional short courses, a K-12 electric vehicle education kit, a Saturday morning seminar series, and a set of consumer education material to support the advancement of transportation electrification. The first four deliverables were all successfully developed and offered. When we held the kick-off meeting in NETL in Morgantown back in early 2010 with all the ten ARRA education teams, however, it quickly became clear that among the ten ARRA education grantee teams, our proposed “consume education” activities are not better or with the potential to create bigger impact than some of activities proposed in other teams. For example, the Odyssey 2010 event held by the West Virginia University team had planned and successfully reached to more than 230,000 attendees, which is way more than what our proposed 100k event could ever reach. It was under the suggestion of Joseph Quaranta, the ARRA education Program Director at that time, that we should coordinate and eliminate redundancy. The resources should then be focused on activities that have less overlap. Therefore, the originally proposed activities: Saturday morning seminar series, and a set of consumer education material were dropped from our scope. We expanded the scope of our “education kit” activity to include some educational materials, mainly in the form of videos. The target audience also changed from general public to K-12 students. The majority of the project cost (~70%) goes toward the establishment of three undergraduate laboratories, which provides critically needed hands-on learning experience for next-generation green mobility engineers. We are very proud that the ARRA money, which was distributed as part of the economy stimulus package back in 2009, was used to invest in laboratories which are already impacting the learning experience of our undergraduate and graduate students, and will continue to do so in the coming decades. The offering and enrollments of the ten undergraduate and graduate courses developed under the support of this educational grant is summarized in the table below. The grant was finalized in September 2009, and four new courses were developed and offered soon after in Winter 2010. The other six courses were developed thereafter. The total number of students who took these new courses over the duration of this grant is just over 1,000. In the first 2 years, under the DOE funding, the courses are offered more regularly. After that, the courses were considered together with other existing courses in the planning of teaching schedule and may not be offered each year. Almost all of the 10 courses have healthy enrollments and we do expect them to be offered continuously in the future. The graduate courses perhaps will be offered every 2-3 years, and the undergraduate courses most likely on a yearly basis.

33 ADVANCED PROPULSION SYSTEMS↗

SPE-4-prime Calculations on Sympathetic detonation and Preliminary Confinement [Slides]

Peak pressure is very low compared with input pressures that lead to detonation in most explosives (> 100 MPa). As an illustration, Gibbs and Popolato data for PETN at density 1.4 g/cc shows a 500 MPa shock transits to detonation only after a run distance of > 10 mm. The above data are consistent with the RP-83 design - the PETN in the detonator gets a real whack from the EBW to achieve prompt initiation. 500 MPa is 5 kilobar, which is a low pressure in the shock initiation arena. The 4 MPa input pressure is 0.04 kilobar, which is very low. After traveling through the intervening geologic media, the pressure will arrive as a ramp rather than a shock, which is much less effective at initiating explosives. In fact, a compression wave may desensitize the explosive. The most sensitive HE, the PETN in the detonator, is shielded by the mass of ANFO and the pentolite boosters, and so the pressure input to the detonator will be significantly less than that experienced by the ANFO. An additional factor is that the abandoned charge was thermally compromised, and the effect of the somewhat elevated temperature on the PETN and the SHANFO is most likely to desensitize them. This has been observed at LLNL with PETN, and the manufacturer of the SHANFO is the source of the information on its response to temperature. The only possibility posited by one of us is failure of the geologic media resulting in a puncture / perforation of the SHANFO charge. If sufficient shear energy were put into this charge, it could conceivably initiate. This is difficult to quantify and seems like a remote possibility, and at any rate is outside the expected behavior of the geologic media as I understand the problem. Information on the effect of temperature on SHANFO is in the enclosed report that analyzes the failure of SPE 4. I think there are additional possibilities that were not evaluated in the report, but it does provide some useful data on SHANFO sensitivity at elevated temperatures. I don't know if you have seen it, so I enclose a copy. PETN (Jon L. Maienschein, PhD Director, LLNL Energetic Materials Center)

58 GEOSCIENCES↗

Efficient Memory Access with NumPy Global Arrays using Local Memory Access

This paper discusses the work completed working with Global Arrays of data on distributed multi-computer systems and improving their performance. The tasks completed were done at Pacific Northwest National Laboratory in the Science Undergrad Laboratory Internship program in the summer of 2013 for the Data Intensive Computing Group in the Fundamental and Computational Sciences DIrectorate. This work was done on the Global Arrays Toolkit developed by this group. This toolkit is an interface for programmers to more easily create arrays of data on networks of computers. This is useful because scientific computation is often done on large amounts of data sometimes so large that individual computers cannot hold all of it. This data is held in array form and can best be processed on supercomputers which often consist of a network of individual computers doing their computation in parallel. One major challenge for this sort of programming is that operations on arrays on multiple computers is very complex and an interface is needed so that these arrays seem like they are on a single computer. This is what global arrays does. The work done here is to use more efficient operations on that data that requires less copying of data to be completed. This saves a lot of time because copying data on many different computers is time intensive. The way this challenge was solved is when data to be operated on with binary operations are on the same computer, they are not copied when they are accessed. When they are on separate computers, only one set is copied when accessed. This saves time because of less copying done although more data access operations were done.

Daily, Jeffrey A.↗

ORNLs Laboratory Directed Research and Development Program (FY 2011 Annual Report)

The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2011. The associated FY 2011 ORNL LDRD Self-Assessment (ORNL/PPA-2012/2) provides financial data and an internal evaluation of the program’s management process.

09 BIOMASS FUELS↗

ORNLs Laboratory Directed Research and Development Program (FY 2012 Annual Report)

The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the US Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2012. The associated FY 2012 ORNL LDRD Self-Assessment (ORNL/PPA-2012/2) provides financial data and an internal evaluation of the program’s management process.

29 ENERGY PLANNING, POLICY, AND ECONOMY↗

ORNLs Laboratory Directed Research and Development Program FY 2013 Annual Report

The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the US Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2013. The associated FY 2013 ORNL LDRD Self-Assessment (ORNL/PPA-2014/2) provides financial data and an internal evaluation of the program’s management process.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

BOCC Blueprint

The Pacific Northwest National Laboratory (PNNL) Facility and Operations (F&O) Division strives to manage performance, to assure long-term health and sustainability for the organization and our staff through innovation and learning. The F&O organization is committed to achieving five strategic outcomes over the next several years. The strategic outcomes are aligned with the Department of Energy (DOE) and PNNL mission and vision. One key outcome important to enabling our vision is to integrate the smartest facilities, connected to the smartest people, by the smartest systems. We call this our SMART3 Initiative. The F&O SMART3 Initiative will connect human capital with intelligent systems, resulting in a best-in-class, integrated facility-operations strategy that improves productivity and optimizes operational costs. The Building Operations Control Center (BOCC) Blueprint is a key deliverable in this effort and will define near-term and long-term objectives aligned with the SMART3 Initiative. The BOCC Blueprint provides a plan to successfully position the BOCC and assure full integration into the new Systems Engineering Laboratory (SEL). The BOCC Blueprint near-term objectives will satisfy each of the three elements of the SMART3 Initiative. 1. The facilities element will be achieved by defining the minimum set of smart sensors for deployment, establishing dashboards and metrics, and initiating a Real-Time Commissioning Program (RT-Cx). 2. The people element will be achieved as F&O and the Energy and Environment Directorate (EED) collaborate, mentor, and cross-train within F&O. The collaboration effort will provide proof of concept by testing, applying and sharing information on facility systems through smart grid, facility re-tuning & audits, and DSOM fault detection and diagnostics. The mentoring and cross-training will be realized by integrating air balance operators, power operators and FMCS specialists within the BOCC. 3. The systems element will be achieved by standardizing the Facility Management Control Systems (FMCS) and Decision Support for Operations and Maintenance (DSOM) development, specifically by implementing facility dashboards and tools. The long-term objectives are to enhance reliability, reduce cost, and demonstrate the “Living Laboratory,” as defined by the way facilities are used to advance research from theoretical to practical applications through scientific collaboration among PNNL’s research and development (R&D) staff. With the BOCC Blueprint defining the objectives to meet the SMART3 Initiative, the BOCC will become a valuable PNNL core competency, and allow for additional R&D opportunities.

99 GENERAL AND MISCELLANEOUS↗

Recovery Act. Sub-Soil Gas and Fluid Inclusion Exploration and Slim Well Drilling, Pumpernickel Valley, Nevada

Nevada Geothermal Power Company (NGP) was awarded DOE Award DE-EE0002834 in January 2010 to conduct sub-soil gas and fluid inclusion studies and slim well drilling at its Black Warrior Project (now known as North Valley) in Washoe and Churchill Counties, Nevada. The project was designed to apply highly detailed, precise, low-cost subsoil and down-hole gas geochemistry methods from the oil and gas industry to identify upflow zone drilling targets in an undeveloped geothermal prospect. NGP ran into multiple institutional barriers with the Black Warrior project relating to property access and extensive cultural survey requirement. NGP requested that the award be transferred to NGP’s Pumpernickel Valley project, due to the timing delay in obtaining permits, along with additional over-budget costs required. Project planning and permit applications were developed for both the original Black Warrior location and at Pumpernickel. This included obtaining proposals from contractors able to conduct required environmental and cultural surveying, designing the two-meter probe survey methodology and locations, and submitting Notices of Intent and liaising with the Bureau of Land Management to have the two-meter probe work approved. The award had an expiry date of April 30, 2013; however, due to the initial project delays at Black Warrior, and the move of the project from Black Warrior to Pumpernickel, NGP requested that the award deadline be extended. DOE was amenable to this, and worked with NGP to extend the deadline. However, following the loss of the Blue Mountain geothermal power plant in Nevada, NGP’s board of directors changed the company’s mandate to one of cash preservation. NGP was unable to move forward with field work on the Pumpernickel property, or any of its other properties, until additional funding was secured. NGP worked to bring in a project partner to form a joint venture on the property, or to buy the property. This was unsuccessful, and NGP notified the DOE on February 13, 2014 that it would not be able to complete the project objectives before the recovery act awards deadline and submitted a mutual termination request to the DOE which was accepted.

15 GEOTHERMAL ENERGY↗