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At least 991 records · Page 55

Dosimetric characterization of two radium sources for retrospective dosimetry studies

Purpose: During the first part of the 20th century, {sup 226}Ra was the most used radionuclide for brachytherapy. Retrospective accurate dosimetry, coupled with patient follow up, is important for advancing knowledge on long-term radiation effects. The purpose of this work was to dosimetrically characterize two {sup 226}Ra sources, commonly used in Sweden during the first half of the 20th century, for retrospective dose–effect studies. Methods: An 8 mg {sup 226}Ra tube and a 10 mg {sup 226}Ra needle, used at Radiumhemmet (Karolinska University Hospital, Stockholm, Sweden), from 1925 to the 1960s, were modeled in two independent Monte Carlo (MC) radiation transport codes: GEANT4 and MCNP5. Absorbed dose and collision kerma around the two sources were obtained, from which the TG-43 parameters were derived for the secular equilibrium state. Furthermore, results from this dosimetric formalism were compared with results from a MC simulation with a superficial mould constituted by five needles inside a glass casing, placed over a water phantom, trying to mimic a typical clinical setup. Calculated absorbed doses using the TG-43 formalism were also compared with previously reported measurements and calculations based on the Sievert integral. Finally, the dose rate at large distances from a {sup 226}Ra point-like-source placed in the center of 1 m radius water sphere was calculated with GEANT4. Results: TG-43 parameters [including g{sub L}(r), F(r, θ), Λ, and s{sub K}] have been uploaded in spreadsheets as additional material, and the fitting parameters of a mathematical curve that provides the dose rate between 10 and 60 cm from the source have been provided. Results from TG-43 formalism are consistent within the treatment volume with those of a MC simulation of a typical clinical scenario. Comparisons with reported measurements made with thermoluminescent dosimeters show differences up to 13% along the transverse axis of the radium needle. It has been estimated that the uncertainty associated to the absorbed dose within the treatment volume is 10%–15%, whereas uncertainty of absorbed dose to distant organs is roughly 20%–25%. Conclusions: The results provided here facilitate retrospective dosimetry studies of {sup 226}Ra using modern treatment planning systems, which may be used to improve knowledge on long term radiation effects. It is surely important for the epidemiologic studies to be aware of the estimated uncertainty provided here before extracting their conclusions.

07 ISOTOPE AND RADIATION SOURCES↗

Investigating Risks Due to Artemis EVA Tempo Via Probabilistic Risk Assessment

Spaceflight operations pose unique challenges to crew health, safety, and resource management. As space agencies and private companies continue to push the boundaries of human exploration, it is essential to understand the risks associated with Extravehicular Activities (EVAs) and develop strategies to mitigate them. The tempo at which EVAs are conducted – the total number and frequency of these activities – can have a profound impact on medical risks, resource consumption, and overall mission success. Probabilistic risk assessment (PRA) provides a powerful framework for evaluating complex systems and identifying potential hazards. Our work employs the Medical Extensible Dynamic Probabilistic Risk Assessment Tool (MEDPRAT) [1] to simulate mission events, occurrence and treatment of medical conditions, and track the utilization of resources. Coupled with the Evidence Library [2], a medical evidence base for exploration-class missions developed by the Exploration Medical Capability within NASA’s Human Research Program, we can estimate these risks with increased fidelity and optimize medical kit contents to meet specific mission requirements. This presentation provides a detailed examination of how EVA tempo influences medical risk estimates for a lunar surface design reference mission. A comprehensive analysis is conducted to assess the additional mass and volume burden imposed on medical kits required to maintain adequate levels of risk mitigation. Furthermore, we estimate the distribution of the number of successful EVAs completed based on the level of task impairment imposed by medical events and flight rules related to specific medical events, such as decompression sickness.

Modeling↗

Sub-10-Micron and Respirable Particles in Lunar Soils

Based on published lunar soil grain size distribution data, we estimate that 1-3% of the mass of typical mature lunar soils is comprised of grains less than 2.5 micrometers in diameter. These particles are in the respirable range (small enough to be inhaled). Estimates are used because the early methods of obtaining grain size distributions did not give reliable results below about 10 micrometers. Grain size analyses of Apollo 11 soil 10084 by a laser diffraction technique shows that this soil contains roughly 2% by volume in the respirable grain size, in agreement with our prior estimate.

Cooper, Bonnie L.↗

Modeling the Performance and Cost of Lithium-Ion Batteries for Electric-Drive Vehicles, Third Edition

This Manual details the Battery Performance and Cost model (BatPaC) developed at Argonne National Laboratory for lithium-ion battery packs used in automotive transportation. The model designs the battery for a specified power, energy, and type of vehicle battery. The cost of the designed battery is then calculated by accounting for every step in the lithium-ion battery manufacturing process. The assumed annual production level directly affects each process step. The total price to vehicle manufacturers calculated by the model represent both our estimates for the present-day costs and projected costs for up to ten years in the future, depending upon the designated scale of production. BatPaC assumes that future plants with production volumes of up to 500,000 EV batteries per year would be highly automated resulting in lower capital equipment and labor costs per unit produced than present day plants that have lower production volumes. All costs are calculated in US$ for the year of the estimate with all input costs for that same year. BatPaC is the only publicly available model of which we are aware that performs a bottom-up lithium-ion battery design and cost calculation. The original model and Manual were publicly peer-reviewed by battery experts assembled by the U.S. Environmental Protection Agency. This revised model and Manual include changes made in response to the comments received from the users; most of the changes were made over a number of years and are summarized here. The purpose of the report is to document the equations and assumptions from which the model has been created. A user of the model will be able to recreate the calculations and perhaps more importantly, understand the driving forces for the results. Instructions for use and illustrations of the model results are also presented. Almost every variable in the calculation may be changed by the user to represent a system different from the default values pre-entered into the program. The distinct advantage of using a bottom-up cost and design model is that the entire power-to-energy space may be traversed to examine the correlation between performance and cost. The BatPaC model accounts for the physical limitations of the electrochemical processes within the battery. Thus, unrealistic designs are penalized in energy density and cost, unlike cost models based on linear extrapolations. Additionally, the consequences on cost and energy density from changes in cell capacity, parallel cell groups, and manufacturing capabilities are easily assessed with the model. New proposed materials may also be examined to translate bench-scale values to the design of full-scale battery packs providing realistic energy densities and prices to the original equipment manufacturer.

25 ENERGY STORAGE↗

Correlation of S-Band Weather Radar Reflectivity and ACTS Propagation Data in Florida

Previous work has shown that Ka-band attenuation due to rainfall and corresponding S-band reflectivity are highly correlated. This paper reports on work whose goal is to determine the feasibility of estimation and, by extension, prediction of one parameter from the other using the Florida ACTS propagation terminal (APT) and the nearby WSR-88D S-band Doppler weather radar facility operated by the National Weather Service. This work is distinguished from previous efforts in this area by (1) the use of a single-polarized radar, preventing estimation of the drop size distribution (e.g., with dual polarization) and (2) the fact that the radar and APT sites are not co-located. Our approach consists of locating the radar volume elements along the satellite slant path and then, from measured reflectivity, estimating the specific attenuation for each associated path segment. The sum of these contributions yields an estimation of the millimeter-wave attenuation on the space-ground link. Seven days of data from both systems are analyzed using this procedure. The results indicate that definite correlation of S-band reflectivity and Ka-band attenuation exists even under the restriciton of this experiment. Based on these results, it appears possible to estimate Ka-band attenuation using widely available operational weather radar data. Conversely, it may be possible to augment current radar reflectivity data and coverage with low-cost attenuation or sky temperature data to improve the estimation of rain rates.

Wolfe, Eric E.↗

Development of soil moisture retrieval algorithm for L-band SAR measurements

A study of algorithm development and testing for soil moisture retrieval for bare fields using L-band synthetic aperture radar (SAR) imagery is reported. First-order surface scattering models predict that the copolarization ratio is sensitive to soil moisture but not to surface roughness. All possible ratios of the co-polarization signals and their linear combinations are evaluated. The best sensitivity to soil moisture is achieved from measurements as predicted by the first-order surface scattering model. The effects of system noise and volume scattering of soil are evaluated. To minimize the effect of the volume scattering, an algorithm which includes both the surface and volume scattering has been developed and tested using Jet Propulsion Laboratory Airborne SAR (JPL AIRSAR) data. The results show that the estimation of soil moisture can be improved after removing the system noise and including the volume scattering effect at large incidence angles.

Shi, Jiancheng↗

Ellipsoidal Fitting Methodology for Defect Clusters in Gallium Arsenide

In assessing the initial spatial distribution of defects from neutron or heavy ion irradiation, it is useful to have a reliable, automated, and fast-running tool to evaluate characteristic metrics such as the number of sub-clusters or the overall cluster volume. The latter metric, for instance, can be utilized to estimate a reference neutron fluence level at which inter-cluster interaction effects begin to become significant. This paper details a methodology to fit an arbitrarily complex defect map with a set of ellipsoids (one per identified sub-cluster) in which the constituent defects of a sub-cluster are determined using fuzzy degree-of-membership analysis. Specifically, a parameterized model is developed for point defects in gallium arsenide. Cluster volume calculations based on the model are compared against convex hull and single- ellipsoid representations. Results show that the parameterized sub-cluster model begins to deviate from the two reference models at a recoil energy of about 100 keV in GaAs, with the convex hull and single-ellipsoid representations increasingly overestimating the volume thereafter.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Evaluation of a semiautomated lung mass calculation technique for internal dosimetry applications

Purpose: The authors sought to evaluate a simple, semiautomated lung mass estimation method using computed tomography (CT) scans obtained using a variety of acquisition techniques and reconstruction parameters for mass correction of medical internal radiation dose-based internal radionuclide radiation absorbed dose estimates.Methods: CT scans of 27 patients with lung cancer undergoing stereotactic body radiation therapy treatment planning with PET/CT were analyzed retrospectively. For each patient, free-breathing (FB) and respiratory-gated 4DCT scans were acquired. The 4DCT scans were sorted into ten respiratory phases, representing one complete respiratory cycle. An average CT reconstruction was derived from the ten-phase reconstructions. Mid expiration breath-hold CT scans were acquired in the same session for many patients. Deep inspiration breath-hold diagnostic CT scans of many of the patients were obtained from different scanning sessions at similar time points to evaluate the effect of contrast administration and maximum inspiration breath-hold. Lung mass estimates were obtained using all CT scan types, and intercomparisons made to assess lung mass variation according to scan type. Lung mass estimates using the FB CT scans from PET/CT examinations of another group of ten male and ten female patients who were 21–30 years old and did not have lung disease were calculated and compared with reference lung mass values. To evaluate the effect of varying CT acquisition and reconstruction parameters on lung mass estimation, an anthropomorphic chest phantom was scanned and reconstructed with different CT parameters. CT images of the lungs were segmented using the OsiriX MD software program with a seed point of about −850 HU and an interval of 1000. Lung volume, and mean lung, tissue, and air HUs were recorded for each scan. Lung mass was calculated by assuming each voxel was a linear combination of only air and tissue. The specific gravity of lung volume was calculated using the formula (lung HU − air HU)/(tissue HU − air HU), and mass = specific gravity × total volume × 1.04 g/cm{sup 3}.Results: The range of calculated lung masses was 0.51–1.29 kg. The average male and female lung masses during FB CT were 0.80 and 0.71 kg, respectively. The calculated lung mass varied across the respiratory cycle but changed to a lesser degree than did lung volume measurements (7.3% versus 15.4%). Lung masses calculated using deep inspiration breath-hold and average CT were significantly larger (p < 0.05) than were some masses calculated using respiratory-phase and FB CT. Increased voxel size and smooth reconstruction kernels led to high lung mass estimates owing to partial volume effects.Conclusions: Organ mass correction is an important component of patient-specific internal radionuclide dosimetry. Lung mass calculation necessitates scan-based density correction to account for volume changes owing to respiration. The range of lung masses in the authors’ patient population represents lung doses for the same absorbed energy differing from 25% below to 64% above the dose found using reference phantom organ masses. With proper management of acquisition parameters and selection of FB or midexpiration breath hold scans, lung mass estimates with about 10% population precision may be achieved.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

A 1 MW, 100 kV, less than 100 kg space based dc-dc power converter

A 1 MW dc-dc power converter has been designed which has an input voltage of 5 kV +/-3 percent, an output voltage of 100 kV +/- 0.25 percent, and a run time of 1000 s at full power. The estimated system mass is 83.8 kg, giving a power density of 11.9 kW/kg. The system exceeded the weight goal of 10 kW/kg through the use of innovative components and system concepts. The system volume is approximately 0.1 cu m, and the overall system efficiency is estimated to be 87 percent. Some of the unique system features include a 50-kHz H-bridge inverter using MOS-controlled thyristors as the switching devices, a resonance transformer to step up the voltage, open-cycle cryogenic hydrogen gas cooling, and a nonrigid, inflatable housing which provides on-demand pressurization of the power converter local environment. This system scales very well to higher output powers. The weight of the 10-MW system with the same input and output voltage requirements and overall system configuration is estimated to be 575.3 kg. This gives a power density of 17.4 kW/kg, significantly higher than the 11.9 kW/kg estimated at 1 MW.

Cooper, J. R.↗

Utilizing Calibrated GPS Reflected Signals to Estimate Soil Reflectivity and Dielectric Constant: Results from SMEX02

Extensive reflected GPS data was collected using a GPS reflectometer installed on an HC130 aircraft during the Soil Moisture Experiment 2002 (SMEX02) near Ames, Iowa. At the same time, widespread surface truth data was acquired in the form of point soil moisture profiles, areal sampling of near-surface soil moisture, total green biomass and precipitation history, among others. Previously, there have been no reported efforts to calibrate reflected GPS data sets acquired over land. This paper reports the results of two approaches to calibration of the data that yield consistent results. It is shown that estimating the strength of the reflected signals by either (1) assuming an approximately specular surface reflection or (2) inferring the surface slope probability density and associated normalization constants give essentially the same results for the conditions encountered in SMEX02. The corrected data is converted to surface reflectivity and then to dielectric constant as a test of the calibration approaches. Utilizing the extensive in-situ soil moisture related data this paper also presents the results of comparing the GPS-inferred relative dielectric constant with the Wang-Schmugge model frequently used to relate volume moisture content to dielectric constant. It is shown that the calibrated GPS reflectivity estimates follow the expected dependence of permittivity with volume moisture, but with the following qualification: The soil moisture value governing the reflectivity appears to come from only the top 1-2 centimeters of soil, a result consistent with results found for other microwave techniques operating at L-band. Nevertheless, the experimentally derived dielectric constant is generally lower than predicted. Possible explanations are presented to explain this result.

Katzberg, Stephen J.↗

Compact Polarimetry in a Low Frequency Spaceborne Context

Compact polarimetry has been shown to be an interesting alternative mode to full polarimetry when global coverage and revisit time are key issues. It consists on transmitting a single polarization, while receiving on two. Several critical points have been identified, one being the Faraday rotation (FR) correction and the other the calibration. When a low frequency electromagnetic wave travels through the ionosphere, it undergoes a rotation of the polarization plane about the radar line of sight for a linearly polarized wave, and a simple phase shift for a circularly polarized wave. In a low frequency radar, the only possible choice of the transmit polarization is the circular one, in order to guaranty that the scattering element on the ground is illuminated with a constant polarization independently of the ionosphere state. This will allow meaningful time series analysis, interferometry as long as the Faraday rotation effect is corrected for the return path. In full-polarimetric (FP) mode, two techniques allow to estimate the FR: Freeman method using linearly polarized data, and Bickel and Bates theory based on the transformation of the measured scattering matrix to a circular basis. In CP mode, an alternate procedure is presented which relies on the bare surface scattering properties. These bare surfaces are selected by the conformity coefficient, invariant with FR. This coefficient is compared to other published classifications to show its potential in distinguishing three different scattering types: surface, doublebounce and volume. The performances of the bare surfaces selection and FR estimation are evaluated on PALSAR and airborne data. Once the bare surfaces are selected and Faraday angle estimated over them, the correction can be applied over the whole scene. The algorithm is compared with both FP techniques. In the last part of the paper, the calibration of a CP system from the point of view of classical matrix transformation methods in polarimetry is proposed.

radar polarization diversity↗

The potential of positron emission tomography for intratreatment dynamic lung tumor tracking: A phantom study

Purpose: This study aims to evaluate the potential and feasibility of positron emission tomography for dynamic lung tumor tracking during radiation treatment. The authors propose a center of mass (CoM) tumor tracking algorithm using gated-PET images combined with a respiratory monitor and investigate the geometric accuracy of the proposed algorithm. Methods: The proposed PET dynamic lung tumor tracking algorithm estimated the target position information through the CoM of the segmented target volume on gated PET images reconstructed from accumulated coincidence events. The information was continuously updated throughout a scan based on the assumption that real-time processing was supported (actual processing time at each frame ≈10 s). External respiratory motion and list-mode PET data were acquired from a phantom programmed to move with measured respiratory traces (external respiratory motion and internal target motion) from human subjects, for which the ground truth target position was known as a function of time. The phantom was cylindrical with six hollow sphere targets (10, 13, 17, 22, 28, and 37 mm in diameter). The measured respiratory traces consisted of two sets: (1) 1D-measured motion from ten healthy volunteers and (2) 3D-measured motion from four lung cancer patients. The authors evaluated the geometric accuracy of the proposed algorithm by quantifying estimation errors (Euclidean distance) between the actual motion of targets (1D-motion and 3D-motion traces) and CoM trajectories estimated by the proposed algorithm as a function of time. Results: The time-averaged error of 1D-motion traces over all trajectories of all targets was 1.6 mm. The error trajectories decreased with time as coincidence events were accumulated. The overall error trajectory of 1D-motion traces converged to within 2 mm in approximately 90 s. As expected, more accurate results were obtained for larger targets. For example, for the 37 mm target, the average error over all 1D-motion traces was 1.1 mm; and for the 10 mm target, the average error over all 1D-motion traces was 2.8 mm. The overall time-averaged error of 3D-motion traces was 1.6 mm, which was comparable to that of the 1D-motion traces. There were small variations in the errors between the 3D-motion traces, although the motion trajectories were very different. The accuracy of the estimates was consistent for all targets except for the smallest. Conclusions: The authors developed an algorithm for dynamic lung tumor tracking using list-mode PET data and a respiratory motion signal, and demonstrated proof-of-principle for PET-guided lung tumor tracking. The overall tracking error in phantom studies is less than 2 mm.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

A BIM-based system for demolition and renovation waste estimation and planning

Highlights: ► We developed a waste estimation system leveraging the BIM technology. ► The system can calculate waste disposal charging fee and pick-up truck demand. ► We presented an example scenario demonstrating this system. ► Automatic, time-saving and wide applicability are the features of the system. - Abstract: Due to the rising worldwide awareness of green environment, both government and contractors have to consider effective construction and demolition (C and D) waste management practices. The last two decades have witnessed the growing importance of demolition and renovation (D and R) works and the growing amount of D and R waste disposed to landfills every day, especially in developed cities like Hong Kong. Quantitative waste prediction is crucial for waste management. It can enable contractors to pinpoint critical waste generation processes and to plan waste control strategies. In addition, waste estimation could also facilitate some government waste management policies, such as the waste disposal charging scheme in Hong Kong. Currently, tools that can accurately and conveniently estimate the amount of waste from construction, renovation, and demolition projects are lacking. In the light of this research gap, this paper presents a building information modeling (BIM) based system that we have developed for estimation and planning of D and R waste. BIM allows multi-disciplinary information to be superimposed within one digital building model. Our system can extract material and volume information through the BIM model and integrate the information for detailed waste estimation and planning. Waste recycling and reuse are also considered in our system. Extracted material information can be provided to recyclers before demolition or renovation to make recycling stage more cooperative and more efficient. Pick-up truck requirements and waste disposal charging fee for different waste facilities will also be predicted through our system. The results could provide alerts to contractors ahead of time at project planning stage. This paper also presents an example scenario with a 47-floor residential building in Hong Kong to demonstrate our D and R waste estimation and planning system. As the BIM technology has been increasingly adopted in the architectural, engineering and construction industry and digital building information models will likely to be available for most buildings (including historical buildings) in the future, our system can be used in various demolition and renovation projects and be extended to facilitate project control.

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

Designing for Small Volume Assembly of Advanced Electronics Packages

We describe a general methodology to Design for Producibility and Reliability (DFPAR) for very small volume production runs. In cases where the entire volume for fabrication is less than five products, traditional Statistical Process Control (SPC) is inadequate due to reliance on statistics of much larger volumes and the Central Limit Theorem. Data acquisition for process parameter estimation from such a small sample size is difficult; however, it is critical to producing high reliability product.

Central Limit Theorem statistics high reliability ↗

Spectral scattering properties of turbid waters

River water samples have been examined for optical scattering properties at wavelengths between 400 and 800 nm. Scattering coefficients were calculated from measurements of beam attenuation and absorption coefficients and are observed to vary with wavelength. At a fixed wavelength, the scattering coefficient is influenced by both phytoplankton concentration (as indicated by chlorophyll a) and suspended solids concentration. Measurements of small angle volume-scattering function indicate that the phase function at an angle of 1.5 deg is not constant for turbid waters and varies with both wavelength and beam attenuation coefficient. These data differ from previously published results for relatively clear oceanic and coastal waters. Caution is required when attempting to estimate scattering coefficient values from single-angle measurements of volume-scattering function.

Whitlock, C. H.↗

Sensing trace levels of molecular species in solution via zinc oxide nanoprobe Raman spectroscopy

Surface-enhanced Raman spectroscopy (SERS) has potential for unique clinical, environmental, and military applications, among many others, but it is limited by a rapid decrease in signal with distance from the sensing surface. For this reason, much study of SERS-based biosensing involves chemical or physical adsorption of analytes to an active surface. Adsorption, however, limits the types of analytes that can be detected and detection sensitivity. The three-dimensional closely packed architecture of zinc oxide (ZnO) nanowires decorated with silver nanoparticles increases SERS intensity, allowing for adsorption-free biosensing. This approach greatly expands the potential applications of Raman spectroscopy as a biosensing technique. This article demonstrates a significant SERS enhancement from silver nanoparticle-decorated ZnO nanoprobes to the Raman spectra of crystal violet, melamine, and adenine solutions. These enhancements were quantified by comparing the intensity of Raman peaks from each of the three solutions through ZnO nanowires decorated with silver nanoparticles with that through bare ZnO nanowires. Estimated enhancement of the Raman signal accounted for the volume difference between solution affected by SERS and solution sensed by the Raman system. More importantly, the detected SERS signal is from molecules in solution and unadsorbed to the sensing surfaces. This lack of adsorption was confirmed by tracking the SERS enhancement of a crystal violet Raman peak over time. This greatly enhances the value and flexibility of Raman spectroscopy as a detection technique for a wide variety of applications.

42 ENGINEERING↗

Axion detection via superfluid 3 He ferromagnetic phase and quantum measurement techniques

We propose to use the nuclear spin excitation in the ferromagnetic A 1 phase of the superfluid 3 He for the axion dark matter detection. This approach is striking in that it is sensitive to the axion-nucleon coupling, one of the most important features of the QCD axion introduced to solve the strong CP problem. We review a quantum mechanical description of the nuclear spin excitation and apply it to the estimation of the axion-induced spin excitation rate. We also describe a possible detection method of the spin excitation in detail and show that the combination of the squeezing of the final state with the Josephson parametric amplifier and the homodyne measurement can enhance the sensitivity. It turns out that this approach gives good sensitivity to the axion dark matter with the mass of $\mathcal{O}$(1) μeV depending on the size of the external magnetic field. We estimate the parameters of experimental setups, e.g., the detector volume and the amplitude of squeezing, required to reach the QCD axion parameter space.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Dosimetric Impact of Intrafraction Motion During RapidArc Stereotactic Vertebral Radiation Therapy Using Flattened and Flattening Filter-Free Beams

Purpose: To study the dosimetric impact of relatively short-duration intrafraction shifts during a single fraction of RapidArc delivery for vertebral stereotactic body radiation therapy (SBRT) using flattened (FF) and flattening filter-free (FFF) beams. Methods and Materials: The RapidArc plans, each with 2 to 3 arcs, were generated for 9 patients using 6-MV FF and 10-MV FFF beams with maximum dose rates of 1000 and 2400 MU/min, respectively. A total of 1272 plans were created to estimate the dosimetric consequences in target and spinal cord volumes caused by intrafraction shifts during one of the arcs. Shifts of 1, 2, and 3 mm for periods of 5, 10, and 30 seconds, and 5 mm for 5 and 10 seconds, were modelled during a part of the arc associated with high doses and steep dose gradients. Results: For FFF plans, shifts of 2 mm over 10 seconds and 30 seconds could increase spinal cord D{sub max} by up to 6.5% and 13%, respectively. Dosimetric deviations in FFF plans were approximately 2-fold greater than in FF plans. Reduction in target coverage was <1% for 83% and 96% of the FFF and FF plans, respectively. Conclusion: Even short-duration intrafraction shifts can cause significant dosimetric deviations during vertebral SBRT delivery, especially when using very high dose rate FFF beams and when the shift occurs in that part of the arc delivering high doses and steep gradients. The impact is greatest on the spinal cord and its planning-at-risk volume. Accurate and stable patient positioning is therefore required for vertebral SBRT.

62 RADIOLOGY AND NUCLEAR MEDICINE↗