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At least 991 records · Page 55

Spatial Predictions and Associated Uncertainty of Annual Soil Respiration at the Global Scale

Abstract Soil respiration (Rs), the soil‐to‐atmosphere CO 2 flux produced by microbes and plant roots, is a critical but uncertain component of the global carbon cycle. Our current understanding of the variability and dynamics is limited by the coarse spatial resolution of existing estimates. We predicted annual Rs and associated uncertainty across the world at 1‐km resolution using a quantile regression forest algorithm trained with observations from the global Soil Respiration Database spanning from 1961 to 2011. This model yielded a global annual Rs estimate of 87.9 Pg C/year with an associated global uncertainty of 18.6 (mean absolute error) and 40.4 (root mean square error) Pg C/year. The estimated annual heterotrophic respiration (Rh), derived from empirical relationships with Rs, was 49.7 Pg C/year over the same period. Predicted Rs rates and associated uncertainty varied widely across vegetation types, with the greatest predicted rates of Rs in evergreen broadleaf forests (accounting for 20.9% of global Rs). The greatest prediction uncertainties were in northern latitudes and arid to semiarid ecosystems, suggesting that these areas should be targeted in future measurement campaigns. This study provides predictions of Rs (and associated prediction uncertainty) at unprecedentedly high spatial resolution across the globe that could help constrain local‐to‐global process‐based models. Furthermore, it provides insights into the large variability of Rs and Rh across vegetation classes and identifies regions and vegetation types with poor model performance that should be prioritized for future data collection.

Warner, D. L.↗

Control logic to track the outputs of a command generator or randomly forced target

A procedure is presented for synthesizing time-invariant control logic to cause the outputs of a linear plant to track the outputs of an unforced (or randomly forced) linear dynamic system. The control logic uses feed-forward of the reference system state variables and feedback of the plant state variables. The feed-forward gains are obtained from the solution of a linear algebraic matrix equation of the Liapunov type. The feedback gains are the usual regulator gains, determined to stabilize (or augment the stability of) the plant, possibly including integral control. The method is applied here to the design of control logic for a second-order servomechanism to follow a linearly increasing (ramp) signal, an unstable third-order system with two controls to track two separate ramp signals, and a sixth-order system with two controls to track a constant signal and an exponentially decreasing signal (aircraft landing-flare or glide-slope-capture with constant velocity).

Trankle, T. L.↗

Quantifying the Influence of Jupiter on the Earth’s Orbital Cycles

A wealth of Earth-sized exoplanets will be discovered in the coming years, providing a large pool of candidates from which the targets for the search for life beyond the solar system will be chosen. The target selection process will require the leveraging of all available information in order to maximize the robustness of the target list and make the most productive use of follow-up resources. Here, we present the results of a suite of n-body simulations that demonstrate the degree to which the orbital architecture of the solar system impacts the variability of Earth’s orbital elements. By varying the orbit of Jupiter and keeping the initial orbits of the other planets constant, we demonstrate how subtle changes in solar system architecture could alter the Earth’s orbital evolution—a key factor in the Milankovitch cycles that alter the amount and distribution of solar insolation, thereby driving periodic climate change on our planet. The amplitudes and frequencies of Earth’s modern orbital cycles fall in the middle of the range seen in our runs for all parameters considered—neither unusually fast nor slow, neither large nor small. This finding runs counter to the “Rare Earth” hypothesis, which suggests that conditions on Earth are so unusual that life elsewhere is essentially impossible. Our results highlight how dynamical simulations of newly discovered exoplanetary systems could be used as an additional means to assess the potential targets of biosignature searches, and thereby help focus the search for life to the most promising targets.

79 ASTRONOMY AND ASTROPHYSICS↗

Kennedy Space Center Coronary Heart Disease Risk Screening Program

The number one cause of death in the U.S. is coronary heart disease (CHD). It is probably a major cause of death and disability in the lives of employees at Kennedy Space Center (KSC) as well. The KSC Biomedical Office used a multifactorial mathematical formula from the Framingham Heart Study to calculate CHD risk probabilities for individuals in a segment of the KSC population that required medical evaluation for job certification. Those assessed to be high-risk probabilities will be targeted for intervention. Every year, several thousand KSC employees require medical evaluations for job related certifications. Most medical information for these evaluations is gathered on-site at one of the KSC or Cape Canaveral Air Station (CCAS) medical clinics. The formula used in the Framingham Heart Study allows calculation of a person's probability of acquiring CHD within 10 years. The formula contains the following variables: Age, Diabetes, Smoking, Left Ventricular Hypertrophy, Blood Pressure (Systolic or Diastolic), Cholesterol, and HDL cholesterol. The formula is also gender specific. It was used to calculate the 10-year probabilities of CHD in KSC employees who required medical evaluations for job certifications during a one-year time frame. This KSC population was profiled and CHD risk reduction interventions could be targeted to those at high risk. Population risk could also be periodically reevaluated to determine the effectiveness of intervention. A 10-year CHD risk probability can be calculated for an individual quite easily while gathering routine medical information. An employee population's CHD risk probability can be profiled graphically revealing high risk segments of the population which can be targeted for risk reduction intervention. The small audience of NASA/contractor physicians, nurses and exercise/fitness professionals at the breakout session received the lecture very well. Approximately one third indicated by a show of hands that they would be interested in implementing a similar program at their NASA Center. Questions were asked pertaining to standardization for age, the validity of using the idealized male values also for the female population, and indications of the screening test's sensitivity and specificity.

Tipton, David A.↗

Marine partially protected areas: drivers of ecological effectiveness

The number of marine protected areas ( MPA s) has grown exponentially worldwide over the past decade in order to meet international targets. Most of these protected areas allow extraction of resources and are therefore designated as “partially protected areas” ( PPA s). However, the effectiveness of PPA s remains unclear due to the high variability of use types permitted. Here, we carried out what we believe to be the first global meta‐analysis of PPA s using a regulation‐based classification system for MPA s to assess their ecological effectiveness. This novel classification allows for unambiguous differentiation between areas according to allowed use, which is the key feature determining PPA performance. Highly and moderately regulated areas exhibited higher biomass and abundance of commercial fish species, whereas fish abundance and biomass in weakly regulated areas differed little from unprotected areas. Notably, the effectiveness of moderately regulated areas can be enhanced by the presence of an adjacent fully protected area. We concluded that limited and well‐regulated uses in PPA s and the presence of an adjacent fully protected area confer ecological benefits, from which socioeconomic advantages are derived.

Zupan, Mirta↗

Hadron mass corrections in semi-inclusive deep-inelastic scattering

We found that the spin-dependent cross sections for semi-inclusive lepton-nucleon scattering are derived in the framework of collinear factorization, including the effects of masses of the target and produced hadron at finite Q 2 . At leading order the cross sections factorize into products of parton distribution and fragmentation functions evaluated in terms of new, mass-dependent scaling variables. Furthermore, the size of the hadron mass corrections is estimated at kinematics relevant for current and future experiments, and the implications for the extraction of parton distributions from semi-inclusive measurements are discussed.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Structural and mechanistic insights into protective non-neutralizing antibodies targeting Crimean-Congo hemorrhagic fever virus nucleocapsid protein

Abstract Crimean-Congo Hemorrhagic Fever Virus (CCHFV) is a tick-borne virus endemic to Africa, Asia, and expanding regions within Europe. With mortality rates approaching 40%, rising incidence, and no currently approved countermeasures, CCHFV is recognized as a priority public health threat. CCHFV nucleocapsid protein (NP) has long been a key target for diagnostics. Recently, NP-specific humoral responses have also been correlated with protection conferred by protective vaccines candidates. Additionally, the first non-neutralizing monoclonal antibody (mAb) 9D5 demonstrated protective efficacy against CCHFV challenge, underscoring NP as a viable antiviral target. Here, nine anti-NP mAb were utilized to identify four antigenic sites on NP as well as localize these sites to the head or stalk domains. These mAb also revealed variable levels of in vivo protection, independent from whether the epitope site is located in the head or stalk regions. Additionally, three X-ray crystallography structures were obtained that included CCHFV NP from strain Afg09-2990 in complex with the most potent mAb (9D5). This, along with additional structures of two unbound NPs, revealed structural elements critical for mAb-9D5 broad-spectrum protective characteristics. These findings provide a path towards the rapid identification of broadly protective anti-NP mAb countermeasures.

Moresco, Vanessa↗

Characterization of hypervelocity metal fragments for explosive initiation

The fragment impact response of two plastic-bonded explosive (PBX) formulations was studied using explosively driven aluminum fragments. A generic aluminum-capped detonator generated sub-mm aluminum particles moving at hypersonic velocities. The ability of these fragments to initiate reaction or otherwise damage two PBX materials was assessed using go/no-go experiments at standoff distances of up to 160 mm. Lower density PBX 9407 (RDX-based) was initiable at up to 115 mm, while higher density PBX 9501 (HMX-based) was only initiable at up to 6 mm. Several techniques were used to characterize the size, distribution, and velocity of the particles. Witness plate materials, including copper and polycarbonate, and backlit high speed video were used to characterize the distribution of particles, finding that the aluminum cap did not fragment homogeneously but rather with larger particles in a ring surrounding finer particles. Finally, precise digital holography experiments were conducted to measure the three-dimensional shape and size of the fastest-moving fragments, which ranged between 100 and 700 μm and traveled between 2.2 and 3.2 km/s. Crucially, these experiments showed variability in the fragmentation in terms of the number of fragments at the leading edge of the fragment field, indicating that both single and multiple shock impacts could be imparted to the target material. As a result, these types of data are critical for safety experiments and hydrocode simulations to quantify shock-to-detonation transition mechanisms and the associated risk-margins for these materials.

36 MATERIALS SCIENCE↗

Measurement of the structure function of the nearly free neutron using spectator tagging in inelastic H 2 ( e , e ' p s ) X scattering with CLAS

In this study, much less is known about neutron structure than that of the proton due to the absence of free neutron targets. Neutron information is usually extracted from data on nuclear targets such as deuterium, requiring corrections for nuclear binding and nucleon off-shell effects. These corrections are model dependent and have significant uncertainties, especially for large values of the Bjorken scaling variable x. As a consequence, the same data can lead to different conclusions, for example, about the behavior of the d quark distribution in the proton at large x.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Characterizing dark matter signals with missing momentum experiments

Fixed target missing-momentum experiments such as LDMX and M 3 are powerful probes of light dark matter and other light, weakly coupled particles beyond the Standard Model (SM). Such experiments involve ~10 GeV beam particles whose energy and momentum are individually measured before and after passing through a suitably thin target. If new states are radiatively produced in the target, the recoiling beam particle loses a large fraction of its initial momentum, and no SM particles are observed in a downstream veto detector. We explore how such experiments can use kinematic variables and experimental parameters, such as beam energy and polarization, to measure properties of the radiated particles and discriminate between models if a signal is discovered. In particular, the transverse momentum of recoiling particles is shown to be a powerful tool to measure the masses of new radiated states, offering significantly better discriminating ability compared to the recoil energy alone. We further illustrate how variations in beam energy, polarization, and lepton flavor (i.e., electron or muon) can be used to disentangle the possible the Lorentz structure of the new interactions.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Kernelized Generalized Likelihood Ratio Test for Spectrum Sensing in Cognitive Radio

Spectrum sensing in next-generation wireless radio networks is considered a key technology to overcome the problem of spectrum scarcity. Unfortunately, many approaches to spectrum sensing do not work well in low signal-to-noise ratio (SNR) environments. This paper proposes and analyzes a new algorithm named kernelized generalized likelihood ratio test (KGLRT) for spectrum sensing in cognitive radio systems to overcome this problem. Effectively, KGLRT uses a nonlinear kernel to map input data onto a high-dimensional feature space; then, the widely accepted (linear) generalized likelihood ratio test is used for hypothesis testing. This new algorithm gives a gain of 4 dB in SNR over its linear counterpart. A theoretical analysis for this algorithm is given for the first time and is shown analogous to algorithms used in image signal processing. The detection metrics are found to be concentrated random variables; furthermore, the probability distributions of the detection metrics are proved to follow the F -distributions, which agree with the results obtained using the concentration inequality. The analytical thresholds are derived for target false-alarm probabilities. Here, the thresholds are independent of noise power; thus, the proposed algorithm can overcome noise uncertainty issues at very low SNR levels. Simulations validate the theoretical results.

47 OTHER INSTRUMENTATION↗

Identification of boosted Higgs bosons decaying into b -quark pairs with the ATLAS detector at 13 TeV

This study describes a study of techniques for identifying Higgs bosons at high transverse momenta decaying into bottom-quark pairs, $H → b\bar{b}$, for proton–proton collision data collected by the ATLAS detector at the Large Hadron Collider at a centre-of-mass energy $\sqrt{\bar{s}}$ = 13 TeV. These decays are reconstructed from calorimeter jets found with the anti-$k_t R$ = 1.0 jet algorithm. To tag Higgs bosons, a combination of requirements is used: b -tagging of $R$ = 0.2 track-jets matched to the large- R calorimeter jet, and requirements on the jet mass and other jet substructure variables. The Higgs boson tagging efficiency and corresponding multijet and hadronic top-quark background rejections are evaluated using Monte Carlo simulation. Several benchmark tagging selections are defined for different signal efficiency targets. The modelling of the relevant input distributions used to tag Higgs bosons is studied in 36 fb -1 of data collected in 2015 and 2016 using $g → b\bar{b}$ and $Z(→ b\bar{b})γ$ event selections in data. Both processes are found to be well modelled within the statistical and systematic uncertainties.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Genesis: A Compiler Framework for Hamiltonian Simulation on Hybrid CV-DV Quantum Computers

We introduce Genesis, the first compiler designed to support Hamiltonian Simulation on hybrid continuous-variable (CV) and discrete-variable (DV) quantum computing systems. Genesis is a two-level compilation system. At the first level, it decomposes an input Hamiltonian into basis gates using the native instruction set of the target hybrid CV-DV quantum computer. At the second level, it tackles the mapping and routing of qumodes/qubits to implement long-range interactions for the gates decomposed from the first level. Rather than a typical implementation that relies on SWAP primitives similar to qubit-based (or DV-only) systems, we propose an integrated design of connectivity-aware gate synthesis and beamsplitter SWAP insertion tailored for hybrid CV-DV systems. We also introduce an OpenQASM-like domain-specific language (DSL) named CVDV-QASM to represent Hamiltonian in terms of Pauli-exponentials and basic gate sequences from the hybrid CVDV gate set. Genesis has successfully compiled several important Hamiltonians, including the Bose-Hubbard model, Z2−Higgs model, Hubbard-Holstein model, Heisenberg model and Electron-vibration coupling Hamiltonians, which are critical in domains like quantum field theory, condensed matter physics, and quantum chemistry. Our implementation is available at Genesis-CVDV-Compiler https://github.com/ruadapt/Genesis-CVDV-Compiler

Chen, Henry↗

A Scalable Mixed-Integer Decomposition Method for Security-Constrained Optimal Power Flow with Complementarity Constraints

This project aimed to develop a scalable algorithm for security-constrained optimal power flow (SCOPF) under contingency scenarios. In particular, the SCOPF problem targeted in the GO Competition is challenging because of the nonconvexity, its nonsmoothness, and the problem size, which increases with the number of contingency events. Complementarity constraints imposed in post-contingency variables are particularly challenging because they lead to a violation of constraint qualifications at any feasible point.

97 MATHEMATICS AND COMPUTING↗

Coupling Kinesin Spindle Protein and Aurora B Inhibition with Apoptosis Induction Enhances Oral Cancer Cell Killing

Many proteins regulating mitosis have emerged as targets for cancer therapy, including the kinesin spindle protein (KSP) and Aurora kinase B (AurB). KSP is crucial for proper spindle pole separation during mitosis, while AurB plays roles in chromosome segregation and cytokinesis. Agents targeting KSP and AurB selectively affect dividing cells and have shown significant activity in vitro. However, these drugs, despite advancing to clinical trials, often yield unsatisfactory outcomes as monotherapy, likely due to variable responses driven by cyclin B degradation and apoptosis signal accumulation networks. Accumulated data suggest that combining emerging antimitotics with various cytostatic drugs can enhance tumor-killing effects compared to monotherapy. Here, we investigated the impact of inhibiting anti-apoptotic signals with the BH3-mimetic Navitoclax in oral cancer cells treated with the selective KSP inhibitor, Ispinesib, or AurB inhibitor, Barasertib, aiming to potentiate cell death. The combination of BH3-mimetics with both KSP and AurB inhibitors synergistically induced substantial cell death, primarily through apoptosis. A mechanistic analysis underlying this synergistic activity, undertaken by live-cell imaging, is presented. Our data underscore the importance of combining BH3-mimetics with antimitotics in clinical trials to maximize their effectiveness.

Silva, João P. N. (ORCID:0000000344554286)↗

THE H α EMISSION OF NEARBY M DWARFS AND ITS RELATION TO STELLAR ROTATION

The high-energy emission from low-mass stars is mediated by the magnetic dynamo. Although the mechanisms by which fully convective stars generate large-scale magnetic fields are not well understood, it is clear that, as for solar-type stars, stellar rotation plays a pivotal role. We present 270 new optical spectra of low-mass stars in the Solar Neighborhood. Combining our observations with those from the literature, our sample comprises 2202 measurements or non-detections of H α emission in nearby M dwarfs. This includes 466 with photometric rotation periods. Stars with masses between 0.1 and 0.6 M {sub ⊙} are well-represented in our sample, with fast and slow rotators of all masses. We observe a threshold in the mass–period plane that separates active and inactive M dwarfs. The threshold coincides with the fast-period edge of the slowly rotating population, at approximately the rotation period at which an era of rapid rotational evolution appears to cease. The well-defined active/inactive boundary indicates that H α activity is a useful diagnostic for stellar rotation period, e.g., for target selection for exoplanet surveys, and we present a mass-period relation for inactive M dwarfs. We also find a significant, moderate correlation between L{sub Hα} / L{sub bol} and variability amplitude: more active stars display higher levels of photometric variability. Consistent with previous work, our data show that rapid rotators maintain a saturated value of L{sub Hα} / L {sub bol}. Our data also show a clear power-law decay in L{sub Hα} / L{sub bol} with Rossby number for slow rotators, with an index of −1.7 ± 0.1.

79 ASTRONOMY AND ASTROPHYSICS↗

Techno-Economic Evaluation of Electrified Vehicle Options in Drayage Fleets

The electrification of drayage fleets offers potential economic and operational benefits, but the financial viability of electrified vehicles remains sensitive to battery cost, energy price, and fleet usage patterns. While total cost of ownership (TCO) is a useful benchmark, fleet operators and investors are equally concerned with investment performance metrics such as payback period (PB) and Internal Rate of Return (IRR), which better reflect financial risks and investment return timelines. This study develops a unified techno-economic framework that jointly evaluates TCO, PB, and IRR to determine when electrified trucks become cost-effective alternatives to diesel trucks. Building on a previously developed cost modeling tool and using real-world telematics data from a Class 8 drayage fleet at the Port of Savannah, the analysis incorporates projected battery cost trajectories, electricity and diesel price trends, vehicle efficiency improvements, and multiple battery capacities. Parameter ranges reflect widely cited projections and observed drayage-duty-cycle variability. A surrogate-modeling method approximates economic performance across thousands of battery cost–electricity price combinations, enabling high-resolution identification of conditions that achieve TCO parity, acceptable PB thresholds, and target IRR levels. Additionally, the study estimates the evolving share of the fleet that can feasibly electrify over time under multiple economic metrics. This integrated framework offers a novel, data-driven approach to inform risk-aware decision-making for fleet electrification and supports investment planning under evolving cost and operational conditions.

Sun, Ruixiao [ORNL] (ORCID:0000000341768676)↗

Seasat over-land scatterometer data. II - Selection of extended area land-target sites for the calibration of spaceborne scatterometers

The post-launch performance verification for future scatterometers can use extended area land targets to calibrate antenna gain patterns and to verify and monitor deployment configurations. For the Ku-band Seasat scatterometer, a region of tropical rain forest in the Amazon basin was used as a homogeneous extended-area land target. As this region is continuously being deforested, other regions are investigated for calibrating scatterometers. The global backscatter coefficients (sigma0) are compared to classifications of natural vegetation and cultivation intensity and the variability with time during the three-month mission is studied. The statistical variability of sigma0 is compared with prior estimates resulting from the known variability of the instrument parameters and communication noise. Data from selected forested regions with relatively homogeneous sigma0 and little time-dependence are presented.

Kennett, Rosemary G.↗