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At least 991 records · Page 55

Sequence and structural implications of a bovine corneal keratan sulfate proteoglycan core protein. Protein 37B represents bovine lumican and proteins 37A and 25 are unique

Amino acid sequence from tryptic peptides of three different bovine corneal keratan sulfate proteoglycan (KSPG) core proteins (designated 37A, 37B, and 25) showed similarities to the sequence of a chicken KSPG core protein lumican. Bovine lumican cDNA was isolated from a bovine corneal expression library by screening with chicken lumican cDNA. The bovine cDNA codes for a 342-amino acid protein, M(r) 38,712, containing amino acid sequences identified in the 37B KSPG core protein. The bovine lumican is 68% identical to chicken lumican, with an 83% identity excluding the N-terminal 40 amino acids. Location of 6 cysteine and 4 consensus N-glycosylation sites in the bovine sequence were identical to those in chicken lumican. Bovine lumican had about 50% identity to bovine fibromodulin and 20% identity to bovine decorin and biglycan. About two-thirds of the lumican protein consists of a series of 10 amino acid leucine-rich repeats that occur in regions of calculated high beta-hydrophobic moment, suggesting that the leucine-rich repeats contribute to beta-sheet formation in these proteins. Sequences obtained from 37A and 25 core proteins were absent in bovine lumican, thus predicting a unique primary structure and separate mRNA for each of the three bovine KSPG core proteins.

NASA Discipline Cell Biology↗

Habituation and adaptation of the vestibuloocular reflex: a model of differential control by the vestibulocerebellum

We habituated the dominant time constant of the horizontal vestibuloocular reflex (VOR) of rhesus and cynomolgus monkeys by repeated testing with steps of velocity about a vertical axis and adapted the gain of the VOR by altering visual input with magnifying and reducing lenses. After baseline values were established, the nodulus and ventral uvula of the vestibulocerebellum were ablated in two monkeys, and the effects of nodulouvulectomy and flocculectomy on VOR gain adaptation and habituation were compared. The VOR time constant decreased with repeated testing, rapidly at first and more slowly thereafter. The gain of the VOR was unaffected. Massed trials were more effective than distributed trials in producing habituation. Regardless of the schedule of testing, the VOR time constant never fell below the time constant of the semicircular canals (approximately 5 s). This finding indicates that only the slow component of the vestibular response, the component produced by velocity storage, was habituated. In agreement with this, the time constant of optokinetic after-nystagmus (OKAN) was habituated concurrently with the VOR. Average values for VOR habituation were obtained on a per session basis for six animals. The VOR gain was adapted by natural head movements in partially habituated monkeys while they wore x 2.2 magnifying or x 0.5 reducing lenses. Adaptation occurred rapidly and reached about +/- 30%, similar to values obtained using forced rotation. VOR gain adaptation did not cause additional habituation of the time constant. When the VOR gain was reduced in animals with a long VOR time constant, there were overshoots in eye velocity that peaked at about 6-8 s after the onset or end of constant-velocity rotation. These overshoots occurred at times when the velocity storage integrator would have been maximally activated by semicircular canal input. Since the activity generated in the canals is not altered by visual adaptation, this finding indicates that the gain element that controls rapid changes in eye velocity in the VOR is separate from that which couples afferent input to velocity storage. Nodulouvulectomy caused a prompt and permanent loss of habituation, returning VOR time constants to initial values. VOR gain adaptation, which is lost after flocculectomy, was unaffected by nodulouvulectomy. Flocculectomy did not alter habituation of the VOR or of OKAN. Using a simplified model of the VOR, the decrease in the duration of vestibular nystagmus due to habituation was related to a decrement in the dominant time constant of the velocity storage integrator (1/h0).(ABSTRACT TRUNCATED AT 400 WORDS).

NASA Discipline Neuroscience↗

Mueller-Lyer decrement: practice or prolonged inspection?

Noting the similarity between the illusion decrement and selective adaptation paradigms, Long has challenged the view that illusion decrement effects reflect a strategic--as opposed to a structural--underlying mechanism, and has called for further research on this issue. To investigate the confound between prolonged free inspection and repeated trials in the standard decrement procedure, the effects of three inspection conditions (continuous, intermittent, and immediate) on the magnitude of the overestimation Mueller-Lyer illusion have been assessed under two levels of trials (a total of two or six judgments). Significant illusion decline was found only under conditions of repeated trials, with either continuous or intermittent inspection. These findings do not support the predictions of purely structural theories (including neural adaptation and efferent readiness theories), according to which degree of decrement should be determined solely by viewing time. Instead, the data demonstrate that illusion decrement is a product of practice, providing converging evidence for the view of decrement as involving a cognitive 'recalibration' or learning process.

Form Perception↗

Discovery of a Transition to Global Spin-Up in EXO 2030+375

EXO 2030+375, a 42 second transient X-ray pulsar with a Be star companion, has been observed to undergo an outburst at nearly every periastron passage for the last 13.5 years. From 1994 through 2002, the global trend in the pulsar spin frequency was spin-down. Using RXTE data from 2003 September, we have observed a transition to global spin-up in EXO 203G+375. Although the spin frequency observations are sparse, the relative spin-up between 2002 June and 2003 September observations along with an overall brightening of the outbursts since mid 2002 observed with the RXTE ASM accompanied by an increase in density of the disk indicated by infrared magnitudes suggest that the pattern observed with BATSE of a roughly constant spin frequency, followed by spin-up, followed by spin-down is repeating. If so this pattern has approximately an 11 year period, similar to the 15 plus or minus 3 year period derived by Wilson et al. (2002) for the precession period of a one-armed oscillation in the Be disk. If this pattern is indeed repeating, we predict a transition from spin-up to spin-down in 2005.

Wilson, Colleen A.↗

Coupled Gravity and Elevation Measurement of Ice Sheet Mass Change

During June 2003, we measured surface gravity at six locations about a glaciological measurement site located on the South-central Greenland Ice. We operated a GPS unit for 90 minutes at each site -the unit was operated simultaneously with a base station unit in Sondrestrom Fjord so as to enable differential, post-processing of the data. We installed an aluminum, accumulation-rate-pole at each site. The base section of the pole also served as the mount for the GPS antenna. Two gravimeters were used simultaneously at each site. Measurements were repeated at each site with at time lapse of at least 50 minutes. We measured snow physical properties in two shallow pits The same measurement sites were occupied in 1981 and all were part of a hexagonal network of geodetic and glaciological measurements established by The Ohio State University in 1980. Additional gravity observations were acquired at three of the sites in 1993 and 1995. Gravity data were collected in conjunction with Doppler satellite measurements of position and elevation in 1981 and global positioning system measurements subsequently. The use of satellite navigation techniques permitted reoccupation of the same sites in each year to within a few 10 s of meters or better. After detrending the gravity data, making adjustments for tides and removing the residual effects of local spatial gradients in gravity, we observe an average secular decrease in gravity of about 0.01 milligal/year, but with tenths of milligal variations about the mean trend. The trend is consistent with a nearly linear increase in surface elevation of between 7 to 10 c d y r (depending on location) as measured by repeated airborne laser altimeter, surface Doppler satellite and GPS elevation measurements. Differences between the residual gravity anomalies after free air correction may be attributable to local mass changes. This project is a collaboration between the Byrd Polar Research Center of the Ohio State University and the Arctic Technology Center of the Danish Technical University.

Jezek, K. C.↗

Evaluation of Treadmill Exercise in a Lower Body Negative Pressure Chamber as a Countermeasure for Weightlessness-Induced Bone Loss: a Bed Rest Study with Identical Twins

Counteracting bone loss is required for future space exploration. We evaluated the ability of treadmill exercise in a LBNP chamber to counteract bone loss in a 30-day bed rest study. Eight pairs of identical twins were randomly assigned to sedentary control or exercise groups. Exercise within LBNP decreased the bone resorption caused by bed rest and may provide a countermeasure for spaceflight. INTRODUCTION: Bone loss is one of the greatest physiological challenges for extended-duration space missions. The ability of exercise to counteract weightlessness-induced bone loss has been studied extensively, but to date, it has proven ineffective. We evaluated the effectiveness of a combination of two countermeasures-treadmill exercise while inside a lower body negative pressure (LBNP) chamber-on bone loss during a 30-day bed rest study. MATERIALS AND METHODS: Eight pairs of identical twins were randomized into sedentary (SED) or exercise/LBNP (EX/LBNP) groups. Blood and urine samples were collected before, several times during, and after the 30-day bed rest period. These samples were analyzed for markers of bone and calcium metabolism. Repeated measures ANOVA was used to determine statistical significance. Because identical twins were used, both time and group were treated as repeated variables. RESULTS: Markers of bone resorption were increased during bed rest in samples from sedentary subjects, including the collagen cross-links and serum and urinary calcium concentrations. For N-telopeptide and deoxypyridinoline, there were significant (p < 0.05) interactions between group (SED versus EX/LBNP) and phase of the study (sample collection point). Pyridinium cross-links were increased above pre-bed rest levels in both groups, but the EX/LBNP group had a smaller increase than the SED group. Markers of bone formation were unchanged by bed rest in both groups. CONCLUSIONS: These data show that this weight-bearing exercise combined with LBNP ameliorates some of the negative effects of simulated weightlessness on bone metabolism. This protocol may pave the way to counteracting bone loss during spaceflight and may provide valuable information about normal and abnormal bone physiology here on Earth.

Twin Study↗

Trends from the Long-term Data Record and Models: What Do They Tell Us About our Ability to Predict Ozone Recovery?

Our industrial society has performed an experiment on the stratospheric ozone layer over the last several decades. The initial part of this experiment was the rapidly increasing release of halogen-containing compounds that carry chlorine and bromine to the stratosphere where they can cause a loss of ozone. The present part of this experiment is the implementation of the Montreal Protocol, which has led to a leveling off of these halogen compounds and the beginning of their slow removal from the atmosphere. The observation and attribution of ozone response to the halogens has been a particularly important and difficult task because of the impact of solar cycle uv variation, two major volcanic eruptions (El Chichon and Pinatubo), and interannual dynamic variability of the stratosphere. We have run 3 different simulations of the chemistry and transport of ozone and the minor constituents that affect ozone to help evaluate our understanding of the causes of ozone change and to assess our ability to predict ozone recovery with the removal of halogens from the stratosphere. One simulation, using the Goddard chemical transport model (CTM), had interannual variability in the dynamics for the entire 50 years of simulation, which included the past 3 decades (1974-2004) and the next 2 decades to 2022. The other two simulations used the Global Modeling Initiative (GMI) CTM with no dynamical variability: one used a the winds and temperatures from a repeating warm Arctic winter and the other used a repeating cold Arctic winter. All simulations included the effects of aerosol surfaces from volcanic eruptions on chemical reactions as well as the variation in UV over the 11-year solar cycle.

Strahan, Susan↗

Recent Advances in Radar Polarimetry and Polarimetric SAR Interferometry

The development of Radar Polarimetry and Radar Interferometry is advancing rapidly, and these novel radar technologies are revamping Synthetic Aperture Radar Imaging decisively. In this exposition the successive advancements are sketched; beginning with the fundamental formulations and high-lighting the salient points of these diverse remote sensing techniques. Whereas with radar polarimetry the textural fine-structure, target-orientation and shape, symmetries and material constituents can be recovered with considerable improvements above that of standard amplitude-only Polarization Radar ; with radar interferometry the spatial (in depth) structure can be explored. In Polarimetric-Interferometric Synthetic Aperture Radar (POL-IN-SAR) Imaging it is possible to recover such co-registered textural plus spatial properties simultaneously. This includes the extraction of Digital Elevation Maps (DEM) from either fully Polarimetric (scattering matrix) or Interferometric (dual antenna) SAR image data takes with the additional benefit of obtaining co-registered three-dimensional POL-IN-DEM information. Extra-Wide-Band POL-IN-SAR Imaging - when applied to Repeat-Pass Image Overlay Interferometry - provides differential background validation and measurement, stress assessment, and environmental stress-change monitoring capabilities with hitherto unattained accuracy, which are essential tools for improved global biomass estimation. More recently, by applying multiple parallel repeat-pass EWB-POL-D(RP)-IN-SAR imaging along stacked (altitudinal) or displaced (horizontal) flight-lines will result in Tomographic (Multi- Interferometric) Polarimetric SAR Stereo-Imaging , including foliage and ground penetrating capabilities. It is shown that the accelerated advancement of these modern EWB-POL-D(RP)-IN-SAR imaging techniques is of direct relevance and of paramount priority to wide-area dynamic homeland security surveillance and local-to-global environmental ground-truth measurement and validation, stress assessment, and stress-change monitoring of the terrestrial and planetary covers. In addition, various closely related topics of (i) acquiring additional and protecting existing spectral windows of the Natural Electromagnetic Spectrum (NES) pertinent to Remote Sensing; (ii) mitigating against common "Radio Frequency Interference (RFI)" and intentional Directive Jamming of Airborne & Space borne POL-IN-SAR Imaging Platforms are appraised.

Boerner, Wolfgang-Martin↗

The Amazing SGR 1806-20

On 2004 December 27, the brightest gamma-ray flare ever recorded was detected by several instruments to be coming from the Soft Gamma Repeater SGR 1806-20. The flare even caused an ionospheric disturbance recorded around the globe by ionizing the Earth's upper atmosphere. SGRs belong to a class of slowly spinning (P = approx. 5-12 seconds) neutron stars with extremely high surface magnetic fields, B approx. 10(exp 15) G. The high magnetic fields of these objects were suggested by Duncan & Thompson, who called them "magnetars" to reflect the nature of the energy source that produces their quiescent and flaring X-ray luminosities. Very rarely, magnetars emit giant flares, extreme events with total energies typically approx. 10(exp 44) ergs, at least a factor of 1000 higher than the more frequent, repeating SGR bursts. Previously, only two giant flares have been recorded: from SGR 0526-66 in 1979 and from SGR 1900+14 in 1998. In this letter we report the detection of a very bright but rapidly fading radio afterglow that indicates a moderately relativistic expansion of plasma ejected from the magnetar. The radio afterglow is estimated to be at least 700 times brighter than that of the Aug 27 event, and is consistent with the hypothesis (also suggested by gamma-ray and X-ray data) that it was intrinsically a much more powerful event. I will discuss here the VLA results and their implications for the SGR flare energetics.

Kouveliotou, Chryssa↗

High-Temperature, Thin-Film Strain Gages Improved

Conventional resistance strain gage technology uses "bonded" strain gages. These foil or wire gages are bonded onto the surface of the test article with glue, ceramic cements, or flame-sprayed ceramics. These bonding agents can, in some instances, limit both the degree of strain transmission from the test structure to the gage and the maximum working temperature of the gage. Also, the bulky, bonded gage normally disrupts aerodynamic gas flow on the surface of the test structure because of its intrusive character. To respond to the urgent needs in aeronautic and aerospace research where stress and temperature gradients are high, aerodynamic effects need to be minimized, and higher operational temperatures are required, the NASA Lewis Research Center developed a thin film strain gage. This gage, a vacuum-deposited thin film formed directly on the surface of a test structure, operates at much higher temperatures than commercially available gages do and with minimal disruption of the aerodynamic flow. The gage uses an alloy, palladium-13 wt % chromium (hereafter, PdCr), which was developed by United Technologies Research Center under a NASA contract. PdCr is structurally stable and oxidation resistant up to at least 1100 C (2000 F); its temperature-induced resistance change is linear, repeatable, and not sensitive to the rates of heating and cooling. An early strain gage, which was made of 25-micrometer-diameter PdCr wire and demonstrated to be useable to 800 C, won an R&D 100 award in 1991. By further improving the purity of the material and by developing gage fabrication techniques that use sputter-deposition, photolithography patterning, and chemical etching, we have made an 8- to 10-m PdCr thin-film strain gage that can measure dynamic and static strain to at least 1100 C. For static strain measurements, a 5-m-thick Pt element serves as a temperature compensator to further minimize the temperature effect of the gage. These thin-film gages provide the advantage of minimally intrusive surface strain measurements and give highly repeatable readings with low drift at temperatures from ambient to 1100 C. This is a 300 C advance in operating temperature over the PdCr wire gage and a 500 C advance over commercially available gages made of other materials.

Source record↗

Subsurface Sampling and Sensing Using Burrowing Moles

Finding evidence for life on Mars will likely require accessing the subsurface since the Martian surface is both hostile to life and to preservation of biosignatures due to the cold dry conditions, the strong W environment, and the presence of strong oxidants. Systems are needed to probe beneath the sun and oxidant baked surface of Mars and return samples to the surface for analysis or to bring the instrument sensing underground. Recognizing this need, the European Space Agency incorporated a small subsurface penetrometer or Mole onto the Beagle 2 Mars lander. Had the 2003 landing been successful, the Mole would have collected samples from 1-1.5 m depth and delivered them to an organic analysis instrument on the surface. The de- vice called the Planetary Underground Tool (PLUTO), also measured soil mechanical and thermophysical properties. Constrained by the small mass and volume allowance of the Beagle lander, the PLUTO mole was a slender cylinder only 2 cm diameter and 28 cm long equipped with a small sampling device designed to collect samples and bring them to the surface for analysis by other instrument. The mass of the entire system including deployment mechanism and tether was 1/2 kg. sensor package underground to make in situ measurements. The Mars Underground Mole (MUM) is a larger Mole based on the PLUTO design but incorporating light collection optics that interface to a fiber optic cable in the tether that transmits light to a combined stimulated emission Raman Spectrometer and Short Wave Infrared (SWIR) reflectance Spectrometer with sensitivity from 0.7 to 2.5 micrometers. This instrument is called the Dual Spectral Sensor and uses a Digital Array Scanning Interferometer as the sensor technology, a type of fourier transform interferometer that uses fixed element prisms and thus is highly rugged compared to a Michaelson interferometer. Due to the size limitations of an on-Mole instrument compartment, and the availability of a tether, the sensor head, light sources, and control electronics for the instrument are on the surface. The DSS sensor is capable of sensing a wide range of minerals relevant to Mars Astrobiology objectives including hydrated minerals, clays, carbonates, sulfates, and ice. Additionally, Raman spectroscopy is effective for detecting organics. The MUM is designed to achieve a maximum depth of penetration of 5 m in Mars regolith and can be repeatedly deployed and retrieved. The ability to perform repeated sampling, combined with the low mass and power requirements, means that Moles could be incorporated into a rover mission as well as used on a stationary platform. The Mole mechanism is a pointed slender cylinder that advances into soil by way of an internal sliding hammer mechanism. Part of the energy released by the spring-loaded hammer with each shock is transferred to the Mole casing and from there to the soil, resulting in penetration by displacing and compressing the surrounding soil. A backwards-directed impulse as a re- action to each forward shock is transferred via a suppressor mass against a second weaker spring allowing forward motion without requiring reactive forces provided by the lander. The Mole tip can be opened to collect soil samples. The Mole casing is tethered to a supporting mechanism that supplies power. Components supporting the Mole on the surface include a launch tube, tether reel and winch for pulling in tether, in addition to the tether itself.

Stoker, C. R.↗

Lithium Polymer Electrolytes and Solid State NMR

Research is being done at the Glenn Research Center (GRC) developing new kinds of batteries that do not depend on a solution. Currently, batteries use liquid electrolytes containing lithium. Problems with the liquid electrolyte are (1) solvents used can leak out of the battery, so larger, more restrictive, packages have to be made, inhibiting the diversity of application and decreasing the power density; (2) the liquid is incompatible with the lithium metal anode, so alternative, less efficient, anodes are required. The Materials Department at GRC has been working to synthesize polymer electrolytes that can replace the liquid electrolytes. The advantages are that polymer electrolytes do not have the potential to leak so they can be used for a variety of tasks, small or large, including in the space rover or in space suits. The polymers generated by Dr. Mary Ann Meador's group are in the form of rod -coil structures. The rod aspect gives the polymer structural integrity, while the coil makes it flexible. Lithium ions are used in these polymers because of their high mobility. The coils have repeating units of oxygen which stabilize the positive lithium by donating electron density. This aids in the movement of the lithium within the polymer, which contributes to higher conductivity. In addition to conductivity testing, these polymers are characterized using DSC, TGA, FTIR, and solid state NMR. Solid state NMR is used in classifying materials that are not soluble in solvents, such as polymers. The NMR spins the sample at a magic angle (54.7') allowing the significant peaks to emerge. Although solid state NMR is a helpful technique in determining bonding, the process of preparing the sample and tuning it properly are intricate jobs that require patience; especially since each run takes about six hours. The NMR allows for the advancement of polymer synthesis by showing if the expected results were achieved. Using the NMR, in addition to looking at polymers, allows for participation on a variety of other projects, including aero-gels and carbon graphite mat en als. The goals of the polymer electrolyte research are to improve the physical properties of the polymers. This includes improving conductivity, durability, and expanding the temperature range over which it is effective. Currently, good conductivity is only present at high temperatures. My goals are to experiment with different arrangements of rods and coils to achieve these desirable properties. Some of my experiments include changing the number of repeat units in the polymer, the size of the diamines, and the types of coil. Analysis of these new polymers indicates improvement in some properties, such as lower glass transition temperature; however, they are not as flexible as desired. With further research we hope to produce polymers that encompass all of these properties to a high degree.

Berkeley, Emily R.↗

Application of Simulated Annealing and Related Algorithms to TWTA Design

Simulated Annealing (SA) is a stochastic optimization algorithm used to search for global minima in complex design surfaces where exhaustive searches are not computationally feasible. The algorithm is derived by simulating the annealing process, whereby a solid is heated to a liquid state and then cooled slowly to reach thermodynamic equilibrium at each temperature. The idea is that atoms in the solid continually bond and re-bond at various quantum energy levels, and with sufficient cooling time they will rearrange at the minimum energy state to form a perfect crystal. The distribution of energy levels is given by the Boltzmann distribution: as temperature drops, the probability of the presence of high-energy bonds decreases. In searching for an optimal design, local minima and discontinuities are often present in a design surface. SA presents a distinct advantage over other optimization algorithms in its ability to escape from these local minima. Just as high-energy atomic configurations are visited in the actual annealing process in order to eventually reach the minimum energy state, in SA highly non-optimal configurations are visited in order to find otherwise inaccessible global minima. The SA algorithm produces a Markov chain of points in the design space at each temperature, with a monotonically decreasing temperature. A random point is started upon, and the objective function is evaluated at that point. A stochastic perturbation is then made to the parameters of the point to arrive at a proposed new point in the design space, at which the objection function is evaluated as well. If the change in objective function values (Delta)E is negative, the proposed new point is accepted. If (Delta)E is positive, the proposed new point is accepted according to the Metropolis criterion: rho((Delta)f) = exp((-Delta)E/T), where T is the temperature for the current Markov chain. The process then repeats for the remainder of the Markov chain, after which the temperature is decremented and the process repeats. Eventually (and hopefully), a near-globally optimal solution is attained as T approaches zero. Several exciting variants of SA have recently emerged, including Discrete-State Simulated Annealing (DSSA) and Simulated Tempering (ST). The DSSA algorithm takes the thermodynamic analogy one step further by categorizing objective function evaluations into discrete states. In doing so, many of the case-specific problems associated with fine-tuning the SA algorithm can be avoided; for example, theoretical approximations for the initial and final temperature can be derived independently of the case. In this manner, DSSA provides a scheme that is more robust with respect to widely differing design surfaces. ST differs from SA in that the temperature T becomes an additional random variable in the optimization. The system is also kept in equilibrium as the temperature changes, as opposed to the system being driven out of equilibrium as temperature changes in SA. ST is designed to overcome obstacles in design surfaces where numerous local minima are separated by high barriers. These algorithms are incorporated into the optimal design of the traveling-wave tube amplifier (TWTA). The area under scrutiny is the collector, in which it would be ideal to use negative potential to decelerate the spent electron beam to zero kinetic energy just as it reaches the collector surface. In reality this is not plausible due to a number of physical limitations, including repulsion and differing levels of kinetic energy among individual electrons. Instead, the collector is designed with multiple stages depressed below ground potential. The design of this multiple-stage collector is the optimization problem of interest. One remaining problem in SA and DSSA is the difficulty in determining when equilibrium has been reached so that the current Markov chain can be terminated. It has been suggested in recent literature that simulating the thermodynamic properties opecific heat, entropy, and internal energy from the Boltzmann distribution can provide good indicators of having reached equilibrium at a certain temperature. These properties are tested for their efficacy and implemented in SA and DSSA code with respect to TWTA collector optimization.

Radke, Eric M.↗

Recreation Embedded State Tuning for Optimal Readiness and Effectiveness (RESTORE)

Physiological self-regulation training is a behavioral medicine intervention that has demonstrated capability to improve psychophysiological coping responses to stressful experiences and to foster optimal behavioral and cognitive performance. Once developed, these psychophysiological skills require regular practice for maintenance. A concomitant benefit of these physiologically monitored practice sessions is the opportunity to track crew psychophysiological responses to the challenges of the practice task in order to detect shifts in adaptability that may foretell performance degradation. Long-duration missions will include crew recreation periods that will afford physiological self-regulation training opportunities. However, to promote adherence to the regimen, the practice experience that occupies their recreation time must be perceived by the crew as engaging and entertaining throughout repeated reinforcement sessions on long-duration missions. NASA biocybernetic technologies and publications have developed a closed-loop concept that involves adjusting or modulating (cybernetic, for governing) a person's task environment based upon a comparison of that person's physiological responses (bio-) with a training or performance criterion. This approach affords the opportunity to deliver physiological self-regulation training in an entertaining and motivating fashion and can also be employed to create a conditioned association between effective performance state and task execution behaviors, while enabling tracking of individuals psychophysiological status over time in the context of an interactive task challenge. This paper describes the aerospace spin-off technologies in this training application area as well as the current spin-back application of the technologies to long-duration missions - the Recreation Embedded State Tuning for Optimal Readiness and Effectiveness (RESTORE) concept. The RESTORE technology is designed to provide a physiological self-regulation training countermeasure for maintaining and reinforcing cognitive readiness, resilience under psychological stress, and effective mood states in long-duration crews. The technology consists of a system for delivering physiological self-regulation training and for tracking crew central and autonomic nervous system function; the system interface is designed to be experienced as engaging and entertaining throughout repeated training sessions on long-duration missions. Consequently, this self-management technology has threefold capability for recreation, behavioral health problem prophylaxis and remediation, and psychophysiological assay. The RESTORE concept aims to reduce the risk of future manned exploration missions by enhancing the capability of individual crewmembers to self-regulate cognitive states through recreation-embedded training protocols to effectively deal with the psychological toll of long-duration space flight.

Pope, Alan T.↗

Discovery of a Transition to Global Spin-up in EXO 2030+375

EXO 2030+375, a 42 s transient X-ray pulsar with a Be star companion, has been observed to undergo an outburst at nearly every periastron passage for the last 13.5 years. From 1994 through 2002, the global trend in the pulsar spin frequency was spin-down. Using Rossi X-Ray Timing Explorer (RXTE) data from 2003 September, we have observed a transition to global spin-up in EXO 2030+375. Although the spin-frequency observations are sparse, the relative spin-up between 2002 June and 2003 September observations, along with an overall brightening of the outbursts since mid-2002 observed with the RXTE All-Sky Monitor, accompanied by an increase in density of the Be disk, indicated by infrared magnitudes, suggest that the pattern observed with BATSE of a roughly constant spin frequency, followed by spin-up, followed by spin-down is repeating. If so, this pattern has approximately an 11 yr period, similar to the 15 +/- 3 yr period derived by Wilson et al. for the precession period of a one-armed oscillation in the Be disk. If this pattern is indeed repeating, we predict a transition from spin-up to spin-down in 2005.

Wilson, Colleen A.↗

Flutter Stability of the Efficient Low Noise Fan Calculated

The TURBO-AE aeroelastic code has been used to verify the flutter stability of the Efficient Low Noise Fan (ELNF), which is also referred to as the trailing-edge blowing fan. The ELNF is a unique technology demonstrator being designed and fabricated at the NASA Glenn Research Center for testing in Glenn's 9-by-15-Foot Low-Speed Wind Tunnel. In the ELNF, air can be blown out of slots near the trailing edges of the fan blades to fill in the wakes downstream of the rotating blades. This filling of the wakes leads to a reduction of the rotor-stator interaction (tone) noise that results from the interaction of wakes with the downstream stators. The ELNF will demonstrate a 1.6-EPNdB1 reduction in tone noise through wake filling, without increasing the broadband noise. Furthermore, the reduced blade row interaction will decrease the possibility of forced response and enable closer spacing of blade rows, thus reducing engine length and weight. During the design of the ELNF, the rotor blades were checked for flutter stability using the detailed aeroelastic analysis capability of the three-dimensional Navier-Stokes TURBOAE code. The aeroelastic calculations were preceded by steady calculations in which the blades were not allowed to vibrate. For each rotational speed, as the back-pressure was increased, the mass flow rate decreased, and the operating point moved along the constant speed characteristic (speed-line) from choke to stall as shown on the fan map. The TURBO-AE aeroelastic analyses were performed separately for the first two vibration modes (bending and torsion) and covered the complete range of interblade phase angles or nodal diameters at which flutter can occur. The results indicated that the ELNF blades would not encounter flutter at takeoff conditions. The calculations were then repeated for a part-speed condition (70-percent rotational speed), and the results again showed no flutter in the operating region. On the fan map (shown), the predicted flutter point at part speed condition was located beyond the stall line, which means that the ELNF will not encounter flutter since it will never operate beyond the stall line. All the calculations done so far have been for the nonblowing case, and selected calculations will be repeated with air blowing from the trailing edge of the fan.

Bakhle, Milind A.↗

Recurrent isolation of hydrogen peroxide-resistant spores of Bacillus pumilus from a spacecraft assembly facility

While the microbial diversity of a spacecraft assembly facility at the Jet Propulsion Laboratory (Pasadena, CA) was being monitored, H2O2-resistant bacterial strains were repeatedly isolated from various surface locations. H2O2 is a possible sterilant for spacecraft hardware because it is a low-temperature process and compatible with various modern-day spacecraft materials, electronics, and components. Both conventional biochemical testing and molecular analyses identified these strains as Bacillus pumilus. This Bacillus species was found in both unclassified (entrance floors, anteroom, and air-lock) and classified (floors, cabinet tops, and air) locations. Both vegetative cells and spores of several B. pumilus isolates were exposed to 5% liquid H2O2 for 60 min. Spores of each strain exhibited higher resistance than their respective vegetative cells to liquid H2O2. Results indicate that the H2O2 resistance observed in both vegetative cells and spores is strain-specific, as certain B. pumilus strains were two to three times more resistant than a standard Bacillus subtilis dosimetry strain. An example of this trend was observed when the type strain of B. pumilus, ATCC 7061, proved sensitive, whereas several environmental strains exhibited varying degrees of resistance, to H2O2. Repeated isolation of H2O2-resistant strains of B. pumilus in a clean-room is a concern because their persistence might potentially compromise life-detection missions, which have very strict cleanliness and sterility requirements for spacecraft hardware.

Spacecraft↗

Track-Level-Compensation Look-Up Table Improves Antenna Pointing Precision

This article presents the improvement of the beam-waveguide antenna pointing accuracy due to the implementation of the track-level-compensation look-up table. It presents the development of the table, from the measurements of the inclinometer tilts to the processing of the measurement data and the determination of the threeaxis alidade rotations. The table consists of three axis rotations of the alidade as a function of the azimuth position. The article also presents the equations to determine the elevation and cross-elevation errors of the antenna as a function of the alidade rotations and the antenna azimuth and elevation positions. The table performance was verified using radio beam pointing data. The pointing error decreased from 4.5 mdeg to 1.4 mdeg in elevation and from 14.5 mdeg to 3.1 mdeg in cross-elevation. I. Introduction The Deep Space Station 25 (DSS 25) antenna shown in Fig. 1 is one of NASA s Deep Space Network beam-waveguide (BWG) antennas. At 34 GHz (Ka-band) operation, it is necessary to be able to track with a pointing accuracy of 2-mdeg root-mean-square (rms). Repeatable pointing errors of several millidegrees of magnitude have been observed during the BWG antenna calibration measurements. The systematic errors of order 4 and lower are eliminated using the antenna pointing model. However, repeatable pointing errors of higher order are out of reach of the model. The most prominent high-order systematic errors are the ones caused by the uneven azimuth track. The track is shown in Fig. 2. Manufacturing and installation tolerances, as well as gaps between the segments of the track, are the sources of the pointing errors that reach over 14-mdeg peak-to-peak magnitude, as reported in [1,2]. This article presents a continuation of the investigations and measurements of the pointing errors caused by the azimuth-track-level unevenness that were presented in [1] and [2], and it presents the implementation results. Track-level-compensation (TLC) look-up tables were created for the DSS 25, DSS 26, DSS 34, and DSS 55 antennas. To date, the most complete and detailed results were obtained for the DSS 25 and DSS 55 antennas. In this article, for brevity of presentation, we present the DSS 25 antenna results only. 1 Communications Ground Systems Section. The research described in this publication was carried out by the Jet Propulsion Laboratory, California Institute of Technology, under a contract with the National Aeronautics and Space Administration.

Gawronski, W.↗