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At least 973 records · Page 54

The calculation of radial dose from heavy ions: predictions of biological action cross sections

The track structure model of heavy ion cross sections was developed by Katz and co-workers in the 1960s. In this model the action cross section is evaluated by mapping the dose-response of a detector to gamma rays (modeled from biological target theory) onto the radial dose distribution from delta rays about the path of the ion. This is taken to yield the radial distribution of probability for a "hit" (an interaction leading to an observable end-point). Radial integration of the probability yields the cross section. When different response from ions of different Z having the same stopping power is observed this model may be indicated. Since the 1960s there have been several developments in the computation of the radial dose distribution, in the measurement of these distributions, and in new radiobiological data against which to test the model. The earliest model, by Butts and Katz made use of simplified delta ray distribution functions, of simplified electron range-energy relations, and neglected angular distributions. Nevertheless it made possible the calculation of cross sections for the inactivation of enzymes and viruses, and allowed extension to tracks in nuclear emulsions and other detectors and to biological cells. It set the pattern for models of observable effects in the matter through which the ion passed. Here we outline subsequent calculations of radial dose which make use of improved knowledge of the electron emission spectrum, the electron range-energy relation, the angular distribution, and some considerations of molecular excitation, of particular interest both close to the path of the ion and the outer limits of electron penetration. These are applied to the modeling of action cross sections for the inactivation of several strains of E-coli and B. subtilis spores where extensive measurements in the "thin-down" region have been made with heavy ion beams. Such calculations serve to test the radial dose calculations at the outer limit of electron penetration. We lack data from which to test these calculations in regions close to the path of the ion aside from our earliest work on latent tracks in plastics, though it appears that the criterion then suggested for the threshold of track formation, of a minimal dose at a minimal distance (of about 20 angstroms, in plastics), remains valid.

NASA Discipline Radiation Health↗

Nozomi Cis-Lunar Phase Orbit Determination

Japan's Institute of Space and Astronautical Science (ISAS) launched Nozomi, its first mission to the planet Mars using the newly developed M-V launch vehicle on July 3, 1998. Scientific objectives of the mission are to study the structure and dynamics of the Martian upper atmosphere and its interaction with the solar wind. Nozomi is a cooperative mission between ISAS and the National Aeronautics and Space Administration (NASA). The NASA contribution includes navigation and tracking services provided by the Jet Propulsion Laboratory (JPL). The spacecraft also serves as an engineering demonstration of basic technology for planetary exploration. One of the new technologies was a unique trajectory, developed by ISAS, which used solar gravitational perturbations at the weak stability boundary as an aid to achieve an Earth-Mars transfer orbit. This trajectory saves approximately 120 m/s of Delta V compared to direct hyperbolic insertion and is considered an enabling technology for the mission. Nozomi was the first spacecraft to employ this trajectory and provided on-orbit validation of the technique. The trajectory was achieved by initially placing the spacecraft in a highly elliptical cis-lunar phasing orbit. Six maneuvers were performed during this period to correct injection errors and target an outbound lunar swingby in September 1998. The gravity assist from the lunar swingby raised apogee to the vicinity of the weak stability boundary. After three more targeting maneuvers, Nozomi performed an inbound lunar swingby followed immediately by a powered Earth swingby in late December 1998. A 420 m/s Trans Mars Insertion (TMI) burn at the final Earth periapsis was intended to place the spacecraft on a heliocentric trajectory leading to Mars orbit insertion in October 1999. Orbit determination for Nozomi is performed in parallel by both ISAS and the Multi-Mission Navigation (MMNAV) group at JPL. This was an advantage for the mission because each group would generate solutions based on data collected from their respective tracking networks. Spacecraft events, such as sequence uplinks and maneuvers, were generally scheduled during passes at the Usuda tracking station in Japan. As a result, maneuver design and reconstruction was derived from MMNAV solutions based on JPL tracking data obtained immediately prior to or following maneuvers. Data was also exchanged between ISAS and MMNAV so orbit determination could be performed on joint data sets in support of critical targeting late in the cis-lunar phase. In this paper, information regarding the MMNAV orbit determination effort for the first six months of the mission is presented. The spacecraft trajectory is characterized first, followed by a discussion of the orbit determination estimation procedure and models. Results from selected orbit solutions are presented and compared against reconstructed trajectories. One area of emphasis in this paper is orbit determination in the vicinity of the weak stability boundary. Precise navigation was necessary to target the second lunar swingby and the powered Earth swingby. Delivery accuracy of 150 m was required for these critical encounters, but a number of factors contributed to the general degradation of orbit determination accuracy. This included the fact that the spacecraft was at apogee, at a range of 1.7 million km and moving at less than I km/sec perpendicular to the line of sight. Nozomi was also close to zero degrees declination where there are known limitations on orbit determination performance. Finally, S-band tracking data was acquired through the Nozomi backup low gain antenna. This antenna is offset from the axis of this spin stabilized spacecraft and superimposed large signatures in the Doppler and range data. These difficulties were overcome by combining long data arcs, spanning several maneuvers, with a high fidelity solar pressure model. The model included a physically accurate representation of the spacecraft structure and a high time resolution orientation model. Observation modeling included the removal of the spin induced Doppler bias, spin signature and per pass correction of range calibration errors applied for data leading up to critical events. As a result, all orbit determination goals were met. A second area of emphasis in this paper is the JPL tracking and orbit determination effort in support of the TMI maneuver. TMI occurred out of contact with ground stations and the JPL Goldstone tracking complex had the first pass following the bum. As a result, MMNAV had the responsibility to make a rapid assessment of the maneuver performance. MMNAV made the determination that a 100 m/s under bum had occurred and promptly informed ISAS via voice lines. ISAS immediately began preparations for a correction maneuver (TMIc), which had to be performed during the next Usuda pass. The near real time assessment by MMNAV provided accurate antenna frequency and pointing updates for the spacecraft acquisition at Usuda and the close coordination between the two agencies enabled the design and successful execution of the TMc maneuver. Propellant consumption during the correction burn dictated that the mission be redesigned. ISAS developed a new plan which adds 3 full solar orbits, two Earth swingbys and one lunar swingby with arrival at Mars in January 2004. The final Mars orbit will still enable the mission to achieve all of its science objectives.

Ryne, Mark↗

Maximum normalized acceleration as a flying qualities parameter

In 1984, Maximum Normalized Rate (MNR) was presented as a Flying Qualities parameter. Subsequent analysis of data from ground based simulation and flight test revealed the utility of a companion parameter, Maximum Normalized Acceleration (MNA). MNR and MNA profiles reveal the presence of both continuous and pulsed compensation strategies during discrete attitude tracking. In addition, MNR appears to be a suitable metric for pilot opinion in the LATHOS data base, while the MNR/MNA relationship is sensitive to pilot-induced-oscillation (PIO) and roll ratcheting problems. As part of an investigation of this problem, Northrop has developed an analysis technique known as the Step Target Method. The Step Target method is essentially a one degree-of-freedom simulation, where an attitude command in the form of a step function is presented to a closed-loop pilot/aircraft model. The two parameters MNR and MNA were shown to be useful in Flying Qualities analysis. MNR was shown to correlate with Pilot Opinion Rating in the LATHOS data base, while MNA reflects PIO and roll ratcheting. Profiles of MNR versus MNA reveal the presence of pulsed compensation strategies in both ground based and in-flight simulation. Furthermore, comparison of continuous and discrete attitude tracking simulation data reveals that these two tracking tasks exhibit independent sensitivities to aircraft characteristics.

Warner, J. S.↗

SYS-5620-Project - Achieving Robust Laser Performance utilizing Historical Shot Experiments - A Systems Engineering Proposal

The National Ignition Facility (NIF) at Lawrence Livermore National Laboratory precisely guides, amplifies, reflects, and focuses 192 powerful laser beams into a target about the size of a pencil eraser in a few billionths of a second, delivering more than 2 million joules of ultraviolet energy and 500 trillion watts of peak power. A crucial goal of the system is to trigger precise implosions of fuel capsules. This is achieved by delivering all 192 beams at user-specified times and locations on the target, minimizing any deviation from the requested performance. Power requirements can vary substantially on each experiment and the facility supports numerous amplifier pumping configurations and their attendant nonlinear effects. To achieve the tight performance required across such a broad array of configurations, constant comparison of measured and requested power delivery are tracked and long-term trends analyzed as a guide to understanding future performance. A very common question asked is given the current state of the laser today – how well would a similar experiment from the past perform today? Additionally, if one were to specify an alternate amplifier configuration using today’s model would and damage limits be exceeded and would there be an increase in performance. The physics model used to make these predictions and equipment protection checks is called the Virtual Beamline (VBL). VBL is used with an incoming desired pulse shape and energy to be delivered on target, and then does an iterative solve to predict the needed injected pulse in the front-end of the system to achieve this result. To effectively guide and predict future NIF experiment performance, laser scientists explore current amplifier configurations and compare them with historical data utilizing a tool called the Reverify Toolbox.

42 ENGINEERING↗

Vehicle Tracking

The detection and tracking of vehicles moving at hypersonic speeds (> Mach 5) at altitudes of ~100 km has been of growing interest due to the ongoing development of hypersonic glide vehicles (HGVs) by the U.S., Russia and China. This challenge is notably different from traditional ballistic missile systems whose re-entry vehicles move at hypersonic velocities but at much higher altitudes on a ballistic course. Hypersonic glide vehicles are also designed to be able to make sudden turns along their flight path making prediction of their trajectories difficult. Their ability to maneuver, combined with their high velocity and altitude make them difficult to track. The combination of these characteristics presents a challenge for anyone attempting to defend against a hypersonic glide vehicle attack by generally shortening the time available to react. That reaction can involve moving potential targets or attempting to detect the hypersonic glide vehicle and intercept it before it reaches the intended target. Figure 1 compares the trajectory of hypersonic vehicles compared to that of a traditional ballistic missile.

42 ENGINEERING↗

Hazard Detection Detector Cards

This report presents a comprehensive summary of five advanced anomaly detection tools developed and deployed by Oak Ridge National Laboratory in support of the VA’s Health Information Technology modernization. These detectors—Order Path Tracker, Trend Watcher, Pain Pointer, Performance Monitor, and Patient Record Flag Detector—leverage statistical and machine learning methods to monitor workflow disruptions, detect anomalies in care sequences and volumes, identify bottlenecks, and track system-level performance metrics across VistA and Millennium systems. All detectors have been integrated into the Health Data Analytics Platform (HDAP), with most having completed deployment and testing using live data from targeted stations in cardiology and oncology domains. This work enhances VA’s capacity for proactive system surveillance, promotes patient safety, and informs data-driven operational improvements across the EHR ecosystem.

97 MATHEMATICS AND COMPUTING↗

Fragmentation cross sections of 28Si at 14.5 GeV/nucleon

We used CR39 plastic nuclear track detectors (C12H18O7) in combination with automatic track measurement techniques to determine total charge changing and partial cross sections for the production of fragments of charge ZF = 6 to ZF = 13 in collisions of 28Si beam nuclei at 14.5 GeV/nucleon in targets H, C, CR39, (C18H38O), Al, Cu, Ag, and Pb. By application of factorization rules, measured partial cross sections are separated into pure nuclear and electromagnetic components. The cross sections for electromagnetic dissociation agree with theoretical models. The results are consistent with a Z2 dependence of virtual photon spectra.

NASA Discipline Number 04-10↗

Head-Worn Displays for NextGen

The operating concepts emerging under the Next Generation air transportation system (NextGen) require new technology and procedures - not only on the ground-side - but also on the flight deck. Flight deck display and decision support technologies are specifically targeted to overcome aircraft safety barriers that might otherwise constrain the full realization of NextGen. One such technology is the very lightweight, unobtrusive head-worn display (HWD). HWDs with an integrated head-tracking system are being researched as they offer significant potential benefit under emerging NextGen operational concepts. Two areas of benefit for NextGen are defined. First, the HWD may be designed to be equivalent to the Head-Up Display (HUD) using Virtual HUD concepts. As such, these operational credits may be provided to significantly more aircraft for which HUD installation is neither practical nor possible. Second, the HWD provides unique display capabilities, such as an unlimited field-of-regard. These capabilities may be integral to emerging NextGen operational concepts, eliminating safety issues which might otherwise constrain the full realization of NextGen. The paper details recent research results, current HWD technology limitations, and future technology development needed to realize HWDs as a enabling technology for NextGen.

Bailey, Randall E.↗

Science Operations with the James Webb Space Telescope

The James Webb Space Telescope (JWST) will be a powerful space observatory whose four science instruments will deliver rich imaging and multiplexed spectroscopic datasets to the astronomical and planetary science communities. The ground segment for JWST, now being designed and built, will carry out JWST's science operations. The ground segment includes: (1) software that the scientific community will use to propose and specify new observations; (2) software that will schedule both science and calibration observations in a way that optimizes observing efficiency while managing the accumulation of momentum; (3) the infrastructure to regularly measure and maintain the telescope's wavefront; (4) orbit determination, ranging, and tracking; (5) communication via the Deep Space Network to command the observatory and retrieve scientific data; (6) onboard scripts that execute each observing program in an event-driven fashion, with occasional interruptions for targets of opportunity or time-critical observations; and (7) a system that processes and calibrates the data into science ready products, automatically recalibrates when calibrations improve, and archives the data for timely access by the principal investigator and later worldwide access by the scientific community. This ground system builds on experience from operating the Hubble Space Telescope, while solving challenges that are unique to the James Webb Space Telescope. In this paper, we describe the elements of the JWST ground system, how it will work operationally from the perspective of the observatory itself, and how a typical user will interact with the system to turn his/her idea into scientific discovery.

Rigby, Jane↗

Performance and Commissioning of the BigBite Timing Hodoscope for Nucleon Form Factor Measurements at Jefferson Lab

The BigBite Timing Hodoscope detector is the primary subject of this thesis. The Super BigBite Spectrometer is a Jefferson Lab Hall A Collaboration project that has and will continue to measure nucleon electromagnetic form factors. This spectrometer includes the Timing Hodoscope which provides high resolution particle timing data for scattered electrons in the electron arm of BigBite. The Timing Hodoscope utilizes 90, 25 × 25 × 600 mm3 scintillator bars stacked on top of each other to form a single detector plane, and these bars are connected to 180 photo-multiplier tubes via light guides. Particles collide with the scintillating material creating a shower of optical photons and these particle events in the bars are collected to generate signals that are readout by the data acquisition (DAQ) electronics. NINO ASIC amplifier-discriminator cards output signals from the photo-multiplier tubes into analogue and logic signals, which are sent to analogue-to-digital (ADC) and time-to-digital (TDC) converter data acquisition readout modules. This data is then used for analysis of the detector. The focus of this thesis is the construction, commissioning, calibration, and performance of the BigBite Timing Hodoscope before and during the first of five nucleon electromagnetic form factor experiments at Jefferson Lab Hall A. Before the neutron magnetic form factor, G n M, experiment, cosmic ray data was collected during commissioning to confirm proper operation of the Timing Hodoscope electronics by observing the ADC and TDC data. Commissioning studies for charge normalization, gain matching, and other ADC and TDC detector data variables were performed before moving the detector into Hall A. Following installation in Hall A, several calibration studies were implemented to fine-tune the detector in preparation for use in the experiment. The calibration studies included analysis of timing cuts, TDC alignment, the time-walk effect, time difference offsets, and scintillator velocity corrections. Once the Timing Hodoscope was well-calibrated, data-taking during the experiment commenced and the beam-on-target data was used to characterize the Timing Hodoscope performance during the G n M experiment run-time. The performance analysis included studies observing energy deposit, cluster size, rates, accidentals, pile-up, tracking efficiency, position resolution, and time resolution. After application of physics cuts to ensure a data set comprised of particle tracks corresponding to elastic electrons, which is the main data of interest for measurement of G n M, the Timing Hodoscope is shown on average across all kinematic settings to have a >98% tracking efficiency, a position resolution of 4-6 cm in the non-dispersive plane and 1.5-2 cm in the dispersive plane, and a time resolution of 500-750 ps. These performance results are compared to a GEANT4 based performance simulation of the BigBite Timing Hodoscope for reference, showing to what degree the measured performance values match those taken from the simulation.

Marinaro, Ralph↗

Wet Waste Hydrothermal Liquefaction and Biocrude Upgrading to Hydrocarbon Fuels: 2021 State of Technology

Each year the U.S. Department of Energy Bioenergy Technologies Office (BETO) assesses progress in their research and development efforts toward sustainable production of renewable fuels (DOE 2016) through the annual state of technology (SOT) assessment. The SOT assessment evaluates the impact of the year’s research progress on the modeled minimum fuel selling price (MFSP) for selected biofuel conversion pathways and measures the current state of the technology relative to defined goal case projections. Supply chain sustainability analysis to track and guide research toward improved greenhouse gas (GHG) emissions, energy usage, water usage and other environmental metrics for the pathway is performed by Argonne National Laboratory (Cai et al. 2018, 2020). Technical and cost targets for a projected goal case set for the year 2022 were previously established for the wet waste hydrothermal liquefaction (HTL) and biocrude upgrading pathway and summarized in a design report (Snowden-Swan et al. 2017). Process performance advancements made for HTL and biocrude hydrotreating have resulted yearly reductions in the modeled MFSP relative to the initial SOT (2018) (Snowden-Swan et al. 2020, 2021). This report summarizes the research and associated techno-economic analysis (TEA) for the pathway 2021 SOT. Methods and economic assumptions for the nth plant analysis used for the TEA are consistent with the design report (Snowden-Swan et al. 2017), with the exception of updates in the modeled cost year (2016) and income tax rate (21%).

09 BIOMASS FUELS↗

Partial Support of the Fast-Track Consensus Study on Foundational Research Gaps and Future Directions for Digital Twins (Final Report)

This study from the National Academies of Sciences, Engineering, and Medicine was launched to explore the foundational research gaps and opportunities for digital twins. As part of the information gathering process, the committee organized three targeted workshops—in engineering, climate sciences, and biomedical sciences—to better understand domain-specific nuances and barriers to developing digital twins. These sessions enabled cross-sector experts to surface field-specific needs, challenges, and open questions related to digital twins. Thousands of participants across multiple domains engaged in the discussions, which workshops were summarized in three separate Proceedings-in-Brief.

42 ENGINEERING↗

Improvements of the gravity field from satellite techniques as proposed to the European Space Agency

A summary of the European Earth Sciences Space Programme and the requirements for each gravity field mapping resulting from this programme are given. Three satellite experiments for gravity field improvement proposed to the European Space Agency in the last years are shortly characterized. One of these experiments, the low-low-SST-SLALOM experiment, based on laser interferometry for a "two target-one Spacelab telescope" configuration, is discussed in more detail. Reasons for the low-low concept selection are given and some mission aspects and a possible system concept for a compact ranging, acquisition and tracking system are presented.

Reigber, C.↗

Mars-Approach Navigation Using In Situ Orbiters

A document discusses the continuing development of a navigation system that would enable a spacecraft to approach Mars on a trajectory precise enough to enable the spacecraft to land within 1 km of a specified location on the Martian surface. This degree of accuracy would represent an order-of-magnitude improvement over that now obtained in radiometric tracking by use of the Deep Space Network. The navigation system would be implemented largely in software running in digital processors in the Electra transceiver, the Mars Network s standard radio transceiver, that would be in both the approaching spacecraft and Mars Network orbiter. The Mars Network is an ad hoc constellation of existing and future Mars science orbiters and dedicated telecommunication orbiters that has been established as a communication and navigation infrastructure to support the exploration of Mars. The software would exploit the sensory and data-processing capabilities of the Electra transceivers to gather Doppler-shift and other radiometric tracking data and process those data into trajectories data that would be accurate to within 0.3 km at the point of entry into the Martian atmosphere (as needed to land within 1 km of a target surface location).

Duncan, Courtney↗

Colonoscopy Screening in the US Astronaut Corps

Historically, colonoscopy screenings for astronauts have been conducted to ensure that astronauts are in good health for space missions. This data has been identified as being useful for determining appropriate occupational surveillance targets and requirements. Colonoscopies in the astronaut corps can be used for: (a) Assessing overall colon health, (b) A point of reference for future tests in current and former astronauts, (c) Following-up and tracking rates of colorectal cancer and polyps; and (d) Comparison to military and other terrestrial populations. In 2003, medical screening requirements for the active astronaut corps changed to require less frequent colonoscopies. Polyp removal during a colonoscopy is an intervention that prevents the polyp from potentially developing into cancer and decreases the individual's risk for colon cancer.

Masterova, K.↗

Simple Wins: Driving Effective Implementation of Energy Efficiency Projects

Small- and medium-sized manufacturers (SMMs) in the United States, making up over 98% of manufacturing firms, account for 48.3% of the sector’s energy consumption. Despite access to energy assessments and technical resources, such as those from the US Department of Energy’s Better Plants program and Industrial Training and Assessment Centers, implementation rates for identified energy-saving measures remain lower than expectations, averaging 47%. Some barriers were identified by other researchers as limited workforce capacity, inadequate training, and time constraints hinder progress. This article studied the development of customized checklists together with the energy assessment report as a practical solution to improve implementation rates for energy efficiency projects among SMMs. The framework for the checklists was grounded in five principles: short, precise, actionable, relevant, and codeveloped (SPARC). A case study of a 500,000-squarefoot SMM demonstrates how tailored checklists targeting significant energy users—such as heating, ventilating and air conditioning (HVAC), lighting, and compressed air systems for this facility—can simplify the process for staff to do facility walkthroughs to monitor best practices and track the progress of energy efficiency project implementation.

Guo, Wei [Oak Ridge National Laboratory (ORNL), Oa↗

GCR Transport in the Brain: Assessment of Self-Shielding, Columnar Damage, and Nuclear Reactions on Cell Inactivation Rates

Radiation shield design is driven by the need to limit radiation risks while optimizing risk reduction with launch mass/expense penalties. Both limitation and optimization objectives require the development of accurate and complete means for evaluating the effectiveness of various shield materials and body-self shielding. For galactic cosmic rays (GCR), biophysical response models indicate that track structure effects lead to substantially different assessments of shielding effectiveness relative to assessments based on LET-dependent quality factors. Methods for assessing risk to the central nervous system (CNS) from heavy ions are poorly understood at this time. High-energy and charge (HZE) ion can produce tissue events resulting in damage to clusters of cells in a columnar fashion, especially for stopping heavy ions. Grahn (1973) and Todd (1986) have discussed a microlesion concept or model of stochastic tissue events in analyzing damage from HZE's. Some tissues, including the CNS, maybe sensitive to microlesion's or stochastic tissue events in a manner not illuminated by either conventional dosimetry or fluence-based risk factors. HZE ions may also produce important lateral damage to adjacent cells. Fluences of high-energy proton and alpha particles in the GCR are many times higher than HZE ions. Behind spacecraft and body self-shielding the ratio of protons, alpha particles, and neutrons to HZE ions increases several-fold from free-space values. Models of GCR damage behind shielding have placed large concern on the role of target fragments produced from tissue atoms. The self-shielding of the brain reduces the number of heavy ions reaching the interior regions by a large amount and the remaining light particle environment (protons, neutrons, deuterons. and alpha particles) may be the greatest concern. Tracks of high-energy proton produce nuclear reactions in tissue, which can deposit doses of more than 1 Gv within 5 - 10 cell layers. Information on rates of cell killing from GCR, including patterns of cell killing from single particle tracks. can provide useful information on expected differences between proton and HZE tracks and clinical experiences with photon irradiation. To model effects on cells in the brain, it is important that transport models accurately describe changes in the GCR due to interactions in the cranium and proximate tissues. We describe calculations of the attenuated GCR particle fluxes at three dose-points in the brain and associated patterns of cell killing using biophysical models. The effects of the brain self-shielding and bone-tissue interface of the skull in modulating the GCR environment are considered. For each brain dose-point, the mass distribution in the surrounding 4(pi) solid angle is characterized using the CAM model to trace 512 rays. The CAM model describes the self-shielding by converting the tissue distribution to mass-equivalent aluminum, and nominal values of spacecraft shielding is considered. Particle transport is performed with the proton, neutron, and heavy-ion transport code HZETRN with the nuclear fragmentation model QMSFRG. The distribution of cells killed along the path of individual GCR ions is modeled using in vitro cell inactivation data for cells with varying sensitivity. Monte Carlo simulations of arrays of inactivated cells are considered for protons and heavy ions and used to describe the absolute number of cell killing events of various magnitude in the brain from the GCR. Included are simulations of positions of inactivated cells from stopping heavy ions and nuclear stars produced by high-energy ions most importantly, protons and neutrons.

Shavers, M. R.↗