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At least 973 records · Page 54

Myocardialization of the cardiac outflow tract

During development, the single-circuited cardiac tube transforms into a double-circuited four-chambered heart by a complex process of remodeling, differential growth, and septation. In this process the endocardial cushion tissues of the atrioventricular junction and outflow tract (OFT) play a crucial role as they contribute to the mesenchymal components of the developing septa and valves in the developing heart. After fusion, the endocardial ridges in the proximal portion of the OFT initially form a mesenchymal outlet septum. In the adult heart, however, this outlet septum is basically a muscular structure. Hence, the mesenchyme of the proximal outlet septum has to be replaced by cardiomyocytes. We have dubbed this process "myocardialization." Our immunohistochemical analysis of staged chicken hearts demonstrates that myocardialization takes place by ingrowth of existing myocardium into the mesenchymal outlet septum. Compared to other events in cardiac septation, it is a relatively late process, being initialized around stage H/H28 and being basically completed around stage H/H38. To unravel the molecular mechanisms that are responsible for the induction and regulation of myocardialization, an in vitro culture system in which myocardialization could be mimicked and manipulated was developed. Using this in vitro myocardialization assay it was observed that under the standard culture conditions (i) whole OFT explants from stage H/H20 and younger did not spontaneously myocardialize the collagen matrix, (ii) explants from stage H/H21 and older spontaneously formed extensive myocardial networks, (iii) the myocardium of the OFT could be induced to myocardialize and was therefore "myocardialization-competent" at all stages tested (H/H16-30), (iv) myocardialization was induced by factors produced by, most likely, the nonmyocardial component of the outflow tract, (v) at none of the embryonic stages analyzed was ventricular myocardium myocardialization-competent, and finally, (vi) ventricular myocardium did not produce factors capable of supporting myocardialization. Copyright 1999 Academic Press.

NASA Discipline Cardiopulmonary↗

The "Quasar" Network Observations in e-VLBI Mode Within the Russian Domestic VLBI Programs

The purpose of the Russian VLBI "Quasar" Network is to carry out astrometrical and geodynamical investigations. Since 2006 purely domestic observational programs with data processing at the IAA correlator have been carried out. To maintain these geodynamical programs e-VLBI technology is being developed and tested. This paper describes the IAA activity of developing a real-time VLBI system using high-speed digital communication links.

Finkelstein, Andrey↗

Simulation of Mission Phases

This position with the Simulation and Graphics Branch (ER7) at Johnson Space Center (JSC) provided an introduction to vehicle hardware, mission planning, and simulation design. ER7 supports engineering analysis and flight crew training by providing high-fidelity, real-time graphical simulations in the Systems Engineering Simulator (SES) lab. The primary project assigned by NASA mentor and SES lab manager, Meghan Daley, was to develop a graphical simulation of the rendezvous, proximity operations, and docking (RPOD) phases of flight. The simulation is to include a generic crew/cargo transportation vehicle and a target object in low-Earth orbit (LEO). Various capsule, winged, and lifting body vehicles as well as historical RPOD methods were evaluated during the project analysis phase. JSC core mission to support the International Space Station (ISS), Commercial Crew Program (CCP), and Human Space Flight (HSF) influenced the project specifications. The simulation is characterized as a 30 meter +V Bar and/or -R Bar approach to the target object's docking station. The ISS was selected as the target object and the international Low Impact Docking System (iLIDS) was selected as the docking mechanism. The location of the target object's docking station corresponds with the RPOD methods identified. The simulation design focuses on Guidance, Navigation, and Control (GNC) system architecture models with station keeping and telemetry data processing capabilities. The optical and inertial sensors, reaction control system thrusters, and the docking mechanism selected were based on CCP vehicle manufacturer's current and proposed technologies. A significant amount of independent study and tutorial completion was required for this project. Multiple primary source materials were accessed using the NASA Technical Report Server (NTRS) and reference textbooks were borrowed from the JSC Main Library and International Space Station Library. The Trick Simulation Environment and User Training Materials version 2013.0 release was used to complete the Trick tutorial. Multiple network privilege and repository permission requests were required in order to access previous simulation models. The project was also an introduction to computer programming and the Linux operating system. Basic C++ and Python syntax was used during the completion of the Trick tutorial. Trick's engineering analysis and Monte Carlo simulation capabilities were observed and basic space mission planning procedures were applied in the conceptual design phase. Multiple professional development opportunities were completed in addition to project duties during this internship through the System for Administration, Training, and Education Resources for NASA (SATERN). Topics include: JSC Risk Management Workshop, CCP Risk Management, Basic Radiation Safety Training, X-Ray Radiation Safety, Basic Laser Safety, JSC Export Control, ISS RISE Ambassador, Basic SharePoint 2013, Space Nutrition and Biochemistry, and JSC Personal Protective Equipment. Additionally, this internship afforded the opportunity for formal project presentation and public speaking practice. This was my first experience at a NASA center. After completing this internship I have a much clearer understanding of certain aspects of the agency's processes and procedures, as well as a deeper appreciation from spaceflight simulation design and testing. I will continue to improve my technical skills so that I may have another opportunity to return to NASA and Johnson Space Center.

Carlstrom, Nicholas Mercury↗

Observational Needs for Improving Ocean and Coupled Reanalysis, S2S Prediction, and Decadal Prediction

Developments in ocean data assimilation (DA) and observing system technologies are intertwined. New observation types lead to new DA methods, and new DA methods such as Coupled Data Assimilation can change the value of existing observations or indicate where new observations can have greater utility for monitoring and prediction. Practitioners are encouraged to make better use of observations that are already available, for example in strongly coupled data assimilation where ocean observations can be used to improve atmospheric analyses and vice versa. Ocean reanalyses are useful for the analysis of climate,as well as initializing operational long-range prediction models. There are remaining challenges for ocean reanalyses due to biases and abrupt changes in the ocean observing system throughout its history, the presence of biases and drifts in models, and simplifying assumptions made in the DA methods. From a governance point of view, more support is needed to interface the observing community and the ocean DA community. For prediction applications, the ocean DA community must work with the ocean observing community to establish protocols for rapid communication of ocean observing data on NWP timescales. There is potential for new observations to enhance the observing system by supporting prediction on multiple timescales, ranging from the typical timescale of numerical weather prediction covering hours to weeks, out to multiple decades. It is highly encouraged that communication be fostered between thesecommunities to allow operational prediction centers the ability to provide guidance to the design of a sustained and adaptive observing network.

Ocean reanalysis↗

Ground state energy and magnetization curve of a frustrated magnetic system from real-time evolution on a digital quantum processor

Models of interacting many-body quantum systems that may realize new exotic phases of matter, notably quantum spin liquids, are challenging to study using even state-of-the-art classical methods such as tensor network simulations. Quantum computing provides a promising route for overcoming these difficulties to find ground states, dynamics, and more. In this paper, we argue that recently developed hybrid quantum-classical algorithms based on real-time evolution are promising methods for solving a particularly important model in the search for spin liquids, the antiferromagnetic Heisenberg model on the two-dimensional kagome lattice. We show how to construct efficient quantum circuits to implement time evolution for the model and to evaluate key observables on the quantum computer, and we argue that the method has favorable scaling with increasing system size. We then restrict to a 12-spin star plaquette from the kagome lattice and a related 8-spin system, and we give an empirical demonstration on these small systems that the hybrid algorithms can efficiently find the ground state energy and the magnetization curve. For these demonstrations, we use four levels of approximation: exact state vectors, exact state vectors with statistical noise from sampling, noisy classical emulators, and (for the 8-spin system only) real quantum hardware, specifically the Quantinuum H1-1 processor; for the noisy simulations and hardware demonstration, we also employ error mitigation strategies based on the symmetries of the Hamiltonian. Our results strongly suggest that these hybrid algorithms present a promising direction for studying quantum spin liquids and more generally for resolving important unsolved problems in condensed matter theory and beyond.

97 MATHEMATICS AND COMPUTING↗

A Three-Dimensional Variational Data Assimilation Scheme for the Regional Ocean Modeling System: Implementation and Basic Experiments

A three-dimensional variational data assimilation scheme for the Regional Ocean Modeling System (ROMS), named ROMS3DVAR, has been described in the work of Li et al. (2008). In this paper, ROMS3DVAR is applied to the central California coastal region, an area characterized by inhomogeneity and anisotropy, as well as by dynamically unbalanced flows. A method for estimating the model error variances from limited observations is presented, and the construction of the inhomogeneous and anisotropic error correlations based on the Kronecker product is demonstrated. A set of single observation experiments illustrates the inhomogeneous and anisotropic error correlations and weak dynamic constraints used. Results are presented from the assimilation of data gathered during the Autonomous Ocean Sampling Network (AOSN) experiment during August 2003. The results show that ROMS3DVAR is capable of reproducing complex flows associated with upwelling and relaxation, as well as the rapid transitions between them. Some difficulties encountered during the experiment are also discussed.

California coastal ocean↗

MiniCarb: a passive, occultation-viewing, 6U CubeSat for observations of CO 2 , CH 4 , and H 2 O

In this report we present the final design, environmental testing, and launch history of MiniCarb, a 6U CubeSat developed through a partnership between NASA Goddard Space Flight Center and Lawrence Livermore National Laboratory. MiniCarb’s science payload, developed at Goddard, was an occultation-viewing, passive laser heterodyne radiometer for observing methane, carbon dioxide, and water vapor in Earth’s atmosphere at ~1.6 µm s -1 . MiniCarb’s satellite, developed at Livermore, implemented their CubeSat Next Generation Bus plug-and-play architecture to produce a modular platform that could be tailored to a range of science payloads. Following the launch on 5 December 2019, MiniCarb traveled to the International Space Station and was set into orbit on 1 February 2020 via Northrop Grumman’s Cygnus capsule which deployed MiniCarb with tipoff rotation of about 20° s (significantly higher than the typical rate of 3° s -1 from prior CubeSats), from which the attitude control system was unable to recover resulting in a loss of power. In spite of this early failure, MiniCarb had many successes including rigorous environmental testing, successful deployment of its solar panels, and a successful test of the radio and communication through the Iridium network. This prior work and enticing cost (approximately $\$2$ M for the satellite and $\$$250 K for the payload) makes MiniCarb an ideal candidate for a low-cost and rapid rebuild as a single orbiter or constellation to globally observe key greenhouse gases.

47 OTHER INSTRUMENTATION↗

Designing reinforcement learning algorithms for building HVAC control: From experimental observation to simulation comparisons

Advanced supervisory-level control with reinforcement learning (RL) is regarded as a promising solution for HVAC systems to minimize energy consumption while maintaining thermal comfort and indoor air quality. However, most RL applications were conducted in the simulation environment rather than real-world HVAC systems. This paper developed a value-based RL controller termed Deep Q-Network (DQN) for a typical central HVAC system and evaluated its performance in a building test facility. By comparing DQN with a rule-based controller, the study not only demonstrated the cases where DQN could properly maintain indoor comfort but also discussed possible reasons why DQN failed in some other situations. Recognizing the limitations of value-based RL algorithms from the experimental tests, a simulation study was conducted to compare DQN with an alternative RL approach, an actor–critic algorithm termed Deep Deterministic Policy Gradient (DDPG). In scenarios with a relatively large action space, DDPG outperformed DQN by requiring fewer computational resources and achieving better thermal comfort, lower energy consumption, and more stable control actions. The findings suggest that the ability of DDPG to handle continuous control variables more effectively allows for faster convergence in training and more precise control in practice, which enhances the overall efficiency and reliability of the HVAC system.

Guo, Fangzhou↗

Quantifying Methane Leak Emissions by Fused Airborne Imaging Spectroscopy with in Situ Surface Mobile and Airborne Observations of a California Producing Oil Field

Methane (CH4) emission budgets remain uncertain and are projected to grow as oil and gas production from short-lived wells increases and their subsequent transport through aging gas distribution networks. Orders-of-magnitude variations in temporal, spatial, and emission scales present a key challenge to leak detection and quantification. Also, the probability distributions for large and stochastic, leaky systems such as geological reservoirs (by natural migration-seeps) and petroleum production from those reservoirs remain largely unknown, needed to address current approach limitations. The scale of many petroleum systems favors remote sensing, but the sensitivity of such systems often precludes detection of weak emissions. Consequently, an accurate evaluation requires that the relative contribution from the emission "tails" of small leaks also be quantified, which is best carried out using high-sensitivity in situ methods. Fusion of remote sensing and in situ approaches leverages complementary capabilities to address these limitations. We show results from mobile surface (AMOG) and airborne in situ (AJAX) and thermal-infrared (TIR) hyperspectral imaging spectroscopy (Mako) data applied to a producing oil field in the California Central Valley near Bakersfield. AMOG is an automobile-based mobile lab that measures 13 trace gases, aerosol size distributions and vertical profiles, 3D winds and other meteorology, and atmospheric column measurements by solar spectroscopy at highway speeds. AJAX measures 5 trace gases and 3D winds at ~140 m/s. Mako is a broad-area TIR imaging spectrometer that can discriminate multiple gases present in each pixel acquired. In situ-derived, total field emissions were 31±16 Gg/yr CH4. This was compared with Mako-derived emissions from all plumes identified across the study site. We found that super-emitters were not the dominant emissions mode and the spatial pattern of plume locations from production infrastructure was correlated to geological structures.

Leifer, Ira↗

ThunderSecure: deploying real-time intrusion detection for 100G research networks by leveraging stream-based features and one-class classification network

Nowadays, data generated by large-scale scientific experiments are on the scale of petabytes per month. These data are transferred through dedicated high-bandwidth networks (40/100G) across distributed sites for processing, storage, and analysis. Like general purpose networks, research networks experience intrusions. However, monitoring anomalies in such high-speed network traffics is challenging given current cyber-infrastructure. Moreover, traditional network intrusion detection systems (NIDS) are signature based. However, anomaly patterns are difficult to define and that rulesets are often not updated frequently enough to reflect the changes of attack behaviors. We present ThunderSecure, a high-throughput, unsupervised learning-based intrusions detection system for 100G research networks. ThunderSecure implements an efficient packet processing and detection pipeline using multi-cores and GPUs. It extracts statistical and temporal features from real-time network data streams and feeds them to a one-class anomaly detection network. A baseline of normal distribution will be created based on the training observation. Testing traffic deviated from the learned profile will be marked as anomalies. We trained ThunderSecure on hundreds of billions of science data packets mirrored from two 100G network connections at Fermi National Accelerator Laboratory. The detection performance was evaluated on traffic captured from the same research network days and weeks after the training with different types of attack flows injected. Results show that ThunderSecure can recognize science data traffic captured long after the training and made nearly certain detection on the segment of the streams where anomalous flows were injected.

100G research network↗

A Global High‐Resolution Mesoscale Convective System Database Using Satellite‐Derived Cloud Tops, Surface Precipitation, and Tracking

Abstract A new methodology is developed to construct a global (60°S–60°N) long‐term (2000–2019) high‐resolution (∼10‐km h) mesoscale convective system (MCS) database by tracking MCS jointly using geostationary satellite infrared brightness temperature ( T b ) and precipitation feature (PF) characteristics from the Integrated Multi‐satellitE Retrievals for GPM precipitation data sets. Independent validation shows that the satellite‐based MCS data set is able to reproduce important MCS statistics derived from ground‐based radar network observations in the United States and China. We show that by carefully considering key PF characteristics in addition to T b signatures, the new method significantly improves upon previous T b ‐only methods in detecting MCSs in the midlatitudes for all seasons. Results show that MCSs account for over 50% of annual total rainfall across most of the tropical belt and in selected regions of the midlatitudes, with a strong seasonality over many regions of the globe. The tracking database allows Lagrangian aspects such as MCS lifetime and translational speed and direction to be analyzed. The longest‐lived MCSs preferentially occur over the subtropical oceans. The land MCSs have higher cloud‐tops associated with more intense convection, and oceanic MCSs have much higher rainfall production. While MCSs are observed in many regions of the globe, there are fundamental differences in their dynamic and thermodynamic structures that warrant a better understanding of processes that control their evolution. This global database provides significant opportunities for observational and modeling studies of MCSs, their characteristics, and roles in regional and global water and energy cycles, as well as their hydrologic and other impacts.

54 ENVIRONMENTAL SCIENCES↗

Data-driven Resilience Characterization of Control Dynamical Systems

In this paper, we define and quantify resiliency of a power network and propose data-driven algorithms for computing the same for the power grid. To do this, we use the Koopman operator framework to lift the controlled dynamical system to an abstract (possibly higher) dimensional space, where the evolution is linear. The linear system representation allows us to relate small time local controllability and observability of a general nonlinear control system to the controllability and observability of the lifted linear system. Finally, we define the resiliency of the underlying power grid in terms of the controllability and observability gramians of the lifted linear system. We illustrate the proposed approach to compute the resiliency metrics on time-series data obtained from a microgrid.

koopman operator, resilience, control↗

Earth observation data systems in the 1980's

The requirements for future data systems for earth resource observation data are examined. Estimates are made for both expected data volumes and data delivery requirements. Research and development activities presently underway are described, including (1) high-speed processors such as the massively parallel processor; (2) data storage systems, including optical disk configurations and (3) distributed data systems such as high-speed local networks and the applications data service system.

Bracken, P. A.↗

Support for global science - Remote sensing's challenge

Advances in remote sensing techniques are discussed. The benefits possible to remote sensing with the new Earth Observing System, which is composed of the Space Station and coorbiting and polar satellite platforms, are examined. Current changes in the remote sensing field, which involve a change from an industrial society to an informational society, force technology to high technology with high touch, short term to long term, centralized to decentralized, hierarchies to networks, and either/or to multiple option systems are studied. The explanatory and objective types of analyses for investigating biophysical, geochemical, and socioeconomic processes are described; the procedures include: morphometric, cause and effect, temporal and functional and ecological system analyses, inventory, mapping, monitoring, and modeling.

Estes, J. E.↗

Suborbital Science Program

Program Objectives: 1) Satellite Calibration and Validation: Provide methods to perform the cal/val requirements for Earth Observing System satellites. 2) New Sensor Development: Provide methods to reduce risk for new sensor concepts and algorithm development prior to committing sensors to operations. 3) Process Studies: Facilitate the acquisition of high spatial/temporal resolution focused measurements that are required to understand small atmospheric and surface structures which generate powerful Earth system effects. 4) Airborne Networking: Develop disruption-tolerant networking to enable integrated multiple scale measurements of critical environmental features. Dryden Capabilities include: a) Aeronautics history of aircraft developments and milestones. b) Extensive history and experience in instrument integration. c) Extensive history and experience in aircraft modifications. d) Strong background in international deployments. e) Long history of reliable and dependable execution of projects. f) Varied aircraft types providing different capabilities, performance and duration.

Vachon, Jacques↗

Evaluation of precipitation indices in suites of dynamically and statistically downscaled regional climate models over Florida

Abstract The present work evaluates historical precipitation and its indices defined by the Expert Team on Climate Change Detection and Indices (ETCCDI) in suites of dynamically and statistically downscaled regional climate models (RCMs) against NOAA’s Global Historical Climatology Network Daily (GHCN-Daily) dataset over Florida. The models examined here are: (1) nested RCMs involved in the North American CORDEX (NA-CORDEX) program, (2) variable resolution Community Earth System Models (VR-CESM), (3) Coupled Model Intercomparison Project phase 5 (CMIP5) models statistically downscaled using localized constructed analogs (LOCA) technique. To quantify observational uncertainty, three in situ-based (PRISM, Livneh, CPC) and three reanalysis (ERA5, MERRA2, NARR) datasets are also evaluated against the station data. The reanalyses and dynamically downscaled RCMs generally underestimate the magnitude of the monthly precipitation and the frequency of the extreme rainfall in summer. The models forced with CanESM2 miss the phase of the seasonality of extreme precipitation. All models and reanalyses severely underestimate both the mean and interannual variability of mean wet-day precipitation (SDII), consecutive dry days (CDD), and overestimate consecutive wet days (CWD). Metric analysis suggests large uncertainty across NA-CORDEX models. Both the LOCA and VR-CESM models perform better than the majority of models. Overall, RegCM4 and WRF models perform poorer than the median model performance. The performance uncertainty across models is comparable to that in the reanalyses. Specifically, NARR performs poorer than the median model performance in simulating the mean indices and MERRA2 performs worse than the majority of models in capturing the interannual variability of the indices.

54 ENVIRONMENTAL SCIENCES↗

Demystify radiation-enhanced hydrogen isotope diffusion in Fe-Ni-Cr austenitic stainless steels

Understanding and containing hydrogen isotope diffusion is crucial for many nuclear applications. In situ experiments have consistently shown that radiation significantly enhances isotope diffusion in austenitic stainless steels. Despite extensive research, the mechanism behind this phenomenon remains elusive, as most radiation-induced defects (e.g., vacancies, dislocations, and grain boundaries) typically trap hydrogen, thereby slowing diffusion. While grain boundaries may increase in-plane diffusivity and interstitials may enhance diffusion due to material swelling, these effects are relatively minor. Utilizing an Fe-Ni-Cr-H interatomic potential for stainless steels, we conducted extensive molecular dynamics simulations to investigate the origins of radiation-enhanced diffusion. Here, our findings reveal that when a system is resolidified, mimicking defects created by radiation displacements, the resulting structure contains a mixture of phases, boundaries, and dislocation networks. This defective structure significantly increases hydrogen diffusivity, enhancing it by approximately 1.7 times at 900 K. These results suggest that the complex defect structures formed during radiation displacements are the primary drivers of the observed diffusion enhancement, providing valuable insights into the mechanisms underlying radiation-enhanced diffusion in nuclear materials.

36 MATERIALS SCIENCE↗

Next-Generation Reverse Logistics Networks of Photovoltaic Recycling: Perspectives and Challenges

With the growing adoption of solar energy as a key component of the global energy transition and its new industrial policy (the Inflation Reduction Act and others), the United States is witnessing a significant increase in solar investments. This surge in installations and domestic and reshored manufacturing of solar photovoltaic (PV) panels brings with it a pressing issue: the proper management of end-of-life (EoL) PV panels. As these panels are decommissioned, either due to reaching the end of their lifespans or due to breakage across the various stages of the forward supply chain, it becomes crucial to establish efficient reverse supply chain logistics systems to address the challenges associated with their disposal, while also unlocking the value of the inherent materials that are of critical value for other forward supply chains. This perspective article examines the challenges regarding EoL PV panels and relevant reverse supply chain and logistics networks, and proposes future research directions based on the gaps observed among academic research, industry, and policy-making challenges. We identify the main bottlenecks and hurdles including, among others, the lack of supportive regulations and absence of structured, optimized recycling infrastructure. To this end, it is proposed that the key to achieving a sustainable reverse supply chain network for solar PV panels lies in relentless end-to-end supply chain cost optimization efforts supported by enabling policies. Moreover, it is proposed that designing systematic decision-making modeling frameworks is vital for examining different possibilities and scenarios for state, region or nation-wide optimization of solar PV reverse supply chain networks. Indicative to this effect, we discuss the development of a Resource-Task-Network (RTN)-based model and demonstrate its application and benefits through a case study. We wrap up with conclusions and future research directions.

circular economy↗