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At least 973 records · Page 54

Electronic availability of microgravity experiments safety and integration requirements documents

This follow-on to NASA Contractor Report 195447, Microgravity Experiments Safety and Integration Requirements Document Tree, provides the details for accessing the systems that contain the official, electronic versions of the documents initially researched in NASA Contractor Report 195447. The data in this report serves as a valuable information source for the NASA Lewis Research Center Project Documentation Center (PDC), as well as for all developers of space experiments. The PDC has acquired the hardware, software, ID's, and passwords necessary to access most of these systems and is now able to provide customers with current document information as well as immediate delivery of available documents in either electronic or hard copy format.

Hogan, Jean M.↗

STS-93 Flight Day 4 Highlights and Crew Activities

The five astronauts aboard the Space Shuttle Columbia began their fourth flight day preparing to make additional celestial observations through the shuttle's windows and continue work with a variety of instruments. Pilot Jeff Ashby and Mission Specialists Steve Hawley and Michael Tognini set up an exercise treadmill and the Treadmill Vibration Information System (TVIS) which measures vibrations and changes in microgravity levels caused by on-orbit workouts. Astronomer Hawley again made observations of Venus, Jupiter and the Moon with the Southwest Ultraviolet Imaging System (SWUIS) as Commander Eileen Collins and Pilot Jeff Ashby put the shuttle in the proper orientation for his observations. Tognini and Coleman checked the bioprocessing experiments, and harvested mouse-ear cress plants as part of the Plant Growth in Microgravity experiment. Collins and Ashby once again fired the shuttle's engines so that the sensors of the Midcourse Space Experiment (MSX) satellite were able to collect ultraviolet, infrared and visible light data. Columbia was orbiting at an altitude of 182 statute miles with all of its systems in excellent condition.

Source record↗

Methods for the culture of C. elegans and S. cerevisiae in microgravity

To support the study of the effects of microgravity on biological systems, our group is developing and testing methods that allow the cultivation of C. elegans and S. cerevisiae in microgravity. Our aim is to develop the experimental means by which investigators may conduct peer reviewed biological experiments with C. elegans or S. cerevisiae in microgravity. Our protocols are aimed at enabling investigators to grow these organisms for extended periods during which samples may be sub-cultured, collected, preserved, frozen, and/or returned to earth for analysis. Data presented include characterization of the growth phenotype of these organisms in liquid medium in OptiCells(TM) (Biocrystal, LTD).

NASA Center ARC↗

R and D work on the constrained vapor bubble system for a microgravity experiment

We are working with Project Scientists R. Balasubramanian and Sang Young Son, and a NASA Projects Team headed by Sue Motil at the Glenn Research Center on the design and development of an experimental system for use on the International Space Station during the year 2006. John Eustace is the coordinator for the flight experiment at Zin-Tech (previously Northrop-Grumman) for the design and development of the Constrained Vapor Bubble Heat Exchanger, CVBHX, cell which will fit into the Light Microscope Module, LMM. Good progress is being made. The CDR for the LMM being developed was held on December 10-1 1,2003. Experimental results obtained under microgravity conditions will be compared with those obtained at Rensselaer. Basic and applied research at Rensselaer continues on the experimental and theoretical details associated with passive phase change heat transfer processes controlled by interfacial forces in the CVBHX. The extensive results of our current research are presented in the 23 external publications listed below. Twenty-two external presentations have been given. Briefly, evaporation/condensation data from both vertical and horizontal CVBHX systems were obtained and analyzed for both polar (wetting) and apolar (partially wetting) fluids. The vertical system is axi-symmetric, but strongly effected by gravity. Whereas, the horizontal system is asymmetric, but weakly effected by gravity. Therefore, there will be significant differences in the operation of the cell in the earth s environment versus the operation under microgravity conditions. Due to its relative large size, the system s performance should be optimum under micro-gravity conditions, where the CVBHX should be a very effective passive heat exchanger. The CVBHX was found to be an ideal experimental setup in which to study the effects of interfacial phenomena on both the evaporation and drop-wise condensation processes. The optical technique (Image Analyzing Interferometry, IAI), which is based on the measurement and analysis of the reflectivity pattern of a thin film, was significantly improved. The accuracy of the IAI system is of critical importance to the success of the mission because it is used to measure the details of the pressure field in the liquid by measuring the film thickness profile. The accuracy was found to be excellent and various publications/presentations documenting these new results were written. Significant new results were also obtained for the effect of the oscillating contact line region on evaporation. Three doctoral students graduated under this grant. All three work in US industry, two for Intel. Another doctoral student is in his third year of study and will finish under an extension of the NASA grant: # NNC05GA27G.

Wayner, P. C., Jr.↗

Planar Strain-Rate-Free Diffusion Flames: Initiation, Properties, and Extinction

An effectively strain-rate-free diffusion flame constitutes the most vigorous laminar combustion of initially unmixed reactive gases. Such a diffusion flame is characterized by a relatively long residence time and by a relatively large characteristic length scale. If such a flame were also planar, providing high symmetry, it would be particularly suitable for experimental and theoretical investigations of key combustion phenomena, such as multicomponent diffusion, chemical kinetics, and soot inception, growth, and oxidation. Unfortunately, a planar strain-rate-free diffusion flame is highly disrupted in earth-gravity (e.g., in a counterflow-diffusion-flame apparatus) because of the very rapid onset (approx. 100 ms) of gravity-induced instability. Accordingly, a specially dedicated apparatus was designed, fabricated, and initially checked out for the examination of a planar strain-rate-free diffusion flame in microgravity. Such a diffusion flame may be formed within a hollowed-out squat container (initially configured as 25 cm x 25 cm x 9 cm), with isothermal, noncatalytic, impervious walls. At test initiation, a thin metallic sheet (approx. 1 mm in thickness) that separates the internal volume into two equal portions, each of dimensions 25 cm x 25 cm x 4.5 cm, is withdrawn, by uniform translation (approx. 50 cm/s) in its own plane, through a tightly fitting slit in one side wall. Thereupon, diluted fuel vapor (initially confined to one half-volume of the container) gains access to diluted oxygen (initially with the same pressure, density, and temperature as the fuel, but initially confined to the other half-volume). After a brief delay (approx. 10 ms), to permit limited but sufficient-for-flammability diffusional interpenetration of fuel vapor and oxidizer, burning is initiated by discharge of a line igniter, located along that side wall from which the trailing edge of the separator withdraws. The ignition spawns a triple-flame propagation across the 25 cm x 25 cm centerplane. When a diffusion flame is emplaced in the centerplane, any subsequent travel, and change in temperature, of that planar diffusion flame may be tracked, along with the effectively spatially uniform but temporally evolving pressure within the container. Eventually, nearly complete depletion of the stoichiometrically deficient reactant, along with heat loss to the container surfaces, effects extinction. These data afford an opportunity to check theoretical models of diffusion and chemical kinetics under conditions ranging from intense burning to flame out, or, alternatively, to evolve simple empirical representations of these phenomena. Thus, the project sought to utilize microgravity testing to elucidate commonly encountered phenomenology, arising in the commonly-encountered mode of combustion (whether related to heating, manufacturing, boiling, and propulsion, or to uncontrolled, free-burning fire in structures and wildland vegetation), of those commonly utilized fuels usually categorized as gaseous fuels (such as hydrogen, natural gas, and propane, which are gaseous under atmospheric conditions).

Fendell, Francis↗

Experiment K-6-05. The maturaton of bone and dentin matrices in rats flown on Cosmos 1887

The chemistry, hydroxyapatite crystal size, and maturation of the bone and dentin is characterized in rats exposed to microgravity for 12.5d in a Soviet Biosatellite (Cosmos-1887). Calvarial and vertebral bone ash was subnormal, but contained a normal percent composition of Ca, P, and Mg. These tissues varied from the norm by having lower Ca/P and higher Ca/Mg ratios than any of their age-matched controls (Vivarium and Synchronous Groups). Gradient density analyses (calvaria) indicated a strong shift to the lower sp.gr. fractions which was commensurate with impaired rates of matrix-mineral maturation. X-ray diffraction data were confirmatory. Bone hydroxyapatite crystal growth in Flight rats was preferentially altered in a way to reduce the dimension of their C-axis. Flight rat dentin was normal with respect to age-matched control Ca, P, Mg, and Zn concentrations and their Ca/P and Ca/Mg ratios. These observations affirm the concept that microgravity adversely affects the maturation of newly formed matrix and mineral moieties in bone.

Simmons, D.↗

Isothermal gas-liquid flow at reduced gravity

Research on adiabatic gas-liquid flows under reduced gravity condition is presented together with experimental data obtained using a NASA-Lewis RC 100-ft drop tower and in a LeRC Learjet. It is found that flow patterns and characteristics remain unchanged after the first 1.5 s into microgravity conditions and that the calculated time for a continuity wave to traverse the test section is less than 1.2 s. It is also found that the dispersed bubbles move at the same velocity as that of the front of the slug and that the transition between bubbly and slug flow is insensitive to diameter. Both the bubbly and the slug flows are suggested to represent a continuum of the same physical process. The characteristics of annular, slug, and bubbly flows are compared.

Dukler, A. E.↗

Modeling Cyclic Phase Change and Energy Storage in Solar Heat Receivers

Numerical results pertaining to cyclic melting and freezing of an encapsulated phase change material (PCM), integrated into a solar heat receiver, have been reported. The cyclic nature of the present melt/freeze problem is relevant to latent heat thermal energy storage (LHTES) systems used to power solar Brayton engines in microgravity environments. Specifically, a physical and numerical model of the solar heat receiver component of NASA Lewis Research Center's Ground Test Demonstration (GTD) project was developed and results compared with available experimental data. Multi-conjugate effects such as the convective fluid flow of a low-Prandtl-number fluid, coupled with thermal conduction in the phase change material, containment tube and working fluid conduit were accounted for in the model. A single-band thermal radiation model was also included to quantify reradiative energy exchange inside the receiver and losses through the aperture. The eutectic LiF-CaF2 was used as the phase change material (PCM) and a mixture of He/Xe was used as the working fluid coolant. A modified version of the computer code HOTTube was used to generate results for comparisons with GTD data for both the subcooled and two-phase regimes. While qualitative trends were in close agreement for the balanced orbit modes, excellent quantitative agreement was observed for steady-state modes.

Hall, Carsie A., III↗

COLLIDE: Collisions into Dust Experiment

The Collisions Into Dust Experiment (COLLIDE) was completed and flew on STS-90 in April and May of 1998. After the experiment was returned to Earth, the data and experiment were analyzed. Some anomalies occurred during the flight which prevented a complete set of data from being obtained. However, the experiment did meet its criteria for scientific success and returned surprising results on the outcomes of very low energy collisions into powder. The attached publication, "Low Velocity Microgravity Impact Experiments into Simulated Regolith," describes in detail the scientific background, engineering, and scientific results of COLLIDE. Our scientific conclusions, along with a summary of the anomalies which occurred during flight, are contained in that publication. We offer it as our final report on this grant.

Colwell, Joshua E.↗

Ground-Based Gas-Liquid Flow Research in Microgravity Conditions: State of Knowledge

During the last decade, ground-based microgravity facilities have been utilized in order to obtain predictions for spacecraft system designers and further the fundamental understanding of two-phase flow. Although flow regime, pressure drop and heat transfer coefficient data has been obtained for straight tubes and a limited number of fittings, measurements of the void fraction, film thickness, wall shear stress, local velocity and void information are also required in order to develop general mechanistic models that can be utilized to ascertain the effects of fluid properties, tube geometry and acceleration levels. A review of this research is presented and includes both empirical data and mechanistic models of the flow behavior.

McQuillen, J.↗

First Protein Crystallization Experiments on The International Space Station: Sweet Success in Space With Thaumatin

We determined the room temperature 1.2 A structure of thaumatin using a crystal grown in the first protein crystallization experiment conducted aboard the International Space Station (ISS). The crystals were grown in the Enhanced Gaseous Nitrogen Dewar (EGN) developed by Alexander McPherson and co-workers. EGN transports frozen solutions contained in tygon tubing in a liquid nitrogen Dewar to ISS where the tubes then thaw. Batch, free interface diffusion (FID), or vapor diffusion crystallization occurs after thawing. EGN was flown to the ISS on STS-106 on September 8, 2000. This was a "risk mitigation" flight that tested EGN performance and the process of conducting experiments on ISS. We focused on how to map a hanging drop crystallization recipe to the EGN FID method. Thaumatin was chosen as the test system. Three series of crystallization recipes were set-up. Each series tested different volume ratios of protein-rich solution to precipitant-rich solution. The series differed from each other by fixing either the protein concentration or the amount of protein in the solutions. Upon return of the samples to Earth on October 24 by STS-92, bubbles that spanned the diameter of the tubing were observed in all tubes. Such bubbles interrupt liquid-liquid diffusion and force vapor diffusion equilibration to occur instead. Nonetheless, crystals grew in 9 of 30 tubes. Many large crystals were grown, the largest being 2.0 x 1.1 x 1.0 cubic mm. The largest crystal was used to collect data at room temperature on beamline 7-1 of the Stanford Synchrotron Radiation Source to a maximum resolution of 1.2 A. The structure was refined anisotropically using SHELX with a data to parameter ratio of 4.5 to give an R(sub factor) of 15.8% (R(sub free) = 18.2%) for ail reflections without generated hydrogens. This refinement is proceeding. Comparisons of this 1.2 A microgravity structure to previous reports of the thaumatin structure at 1.75 A and to ground control crystals will be presented.

Kundrot, Craig E.↗

Student Drop Tower Competitions: Dropping In a Microgravity Environment (DIME) and What If No Gravity? (WING)

This paper describes two student competition programs that allow student teams to conceive a science or engineering experiment for a microgravity environment. Selected teams design and build their experimental hardware, conduct baseline tests, and ship their experiment to NASA where it is operated in the 2.2 Second Drop Tower. The hardware and acquired data is provided to the teams after the tests are conducted so that the teams can prepare their final reports about their findings.

Hall, Nancy R.↗

Sensitivity Analysis of the Bone Fracture Risk Model

Introduction: The probability of bone fracture during and after spaceflight is quantified to aid in mission planning, to determine required astronaut fitness standards and training requirements and to inform countermeasure research and design. Probability is quantified with a probabilistic modeling approach where distributions of model parameter values, instead of single deterministic values, capture the parameter variability within the astronaut population and fracture predictions are probability distributions with a mean value and an associated uncertainty. Because of this uncertainty, the model in its current state cannot discern an effect of countermeasures on fracture probability, for example between use and non-use of bisphosphonates or between spaceflight exercise performed with the Advanced Resistive Exercise Device (ARED) or on devices prior to installation of ARED on the International Space Station. This is thought to be due to the inability to measure key contributors to bone strength, for example, geometry and volumetric distributions of bone mass, with areal bone mineral density (BMD) measurement techniques. To further the applicability of model, we performed a parameter sensitivity study aimed at identifying those parameter uncertainties that most effect the model forecasts in order to determine what areas of the model needed enhancements for reducing uncertainty. Methods: The bone fracture risk model (BFxRM), originally published in (Nelson et al) is a probabilistic model that can assess the risk of astronaut bone fracture. This is accomplished by utilizing biomechanical models to assess the applied loads; utilizing models of spaceflight BMD loss in at-risk skeletal locations; quantifying bone strength through a relationship between areal BMD and bone failure load; and relating fracture risk index (FRI), the ratio of applied load to bone strength, to fracture probability. There are many factors associated with these calculations including environmental factors, factors associated with the fall event, mass and anthropometric values of the astronaut, BMD characteristics, characteristics of the relationship between BMD and bone strength and bone fracture characteristics. The uncertainty in these factors is captured through the use of parameter distributions and the fracture predictions are probability distributions with a mean value and an associated uncertainty. To determine parameter sensitivity, a correlation coefficient is found between the sample set of each model parameter and the calculated fracture probabilities. Each parameters contribution to the variance is found by squaring the correlation coefficients, dividing by the sum of the squared correlation coefficients, and multiplying by 100. Results: Sensitivity analyses of BFxRM simulations of preflight, 0 days post-flight and 365 days post-flight falls onto the hip revealed a subset of the twelve factors within the model which cause the most variation in the fracture predictions. These factors include the spring constant used in the hip biomechanical model, the midpoint FRI parameter within the equation used to convert FRI to fracture probability and preflight BMD values. Future work: Plans are underway to update the BFxRM by incorporating bone strength information from finite element models (FEM) into the bone strength portion of the BFxRM. Also, FEM bone strength information along with fracture outcome data will be incorporated into the FRI to fracture probability.

mathematical models↗

Accuracy of Center of Pressure Determination via Motion Capture

BACKGROUND: This study was conducted to support the stability assessment for tasks in lunar gravity and exercises on a Vibration Isolation and Stabilization (VIS) system in microgravity based on the dynamic feasibility criterion of whether the calculated position of the center of pressure (COP) falls within the base of support (BOS) which outlines the subject’s feet. Motion capture data combined with biomechanical modeling and simulation allows the forces and moments between the human and the VIS platform to be computed and the position of the COP as well as the location and shape of the BOS to be determined. The goal of this study was to assess the accuracy of the COP trajectory calculated using motion capture-based data. METHODS AND RESULTS: To obtain the dynamic quantities from which COP is calculated, motion capture data is first collected in the 1g lab environment by recording the trajectories of passive retroreflective markers placed on a subject during exercise or performance of a given task. The OpenSim [1] inverse kinematics (IK) tool is used to fit a scaled subject model to recorded marker trajectories while minimizing marker error to obtain joint angles. Then, a custom OpenSim plugin [2] is used to determine the subject’s time-varying moment of inertia and its time derivative, center of mass (CM) position, velocity, and acceleration, as well as the angular momentum and its time derivative relative to the subject’s CM. Some of these quantities are not needed for modeling tasks performed on a stationary lunar surface but, due to the moving exercise platform, are needed to model VIS response to the subject’s motion. Hand positions, used in calculating a cable force if present, are recorded as well. These quantities are used to calculate the total force (F ⃗^((plate) )) and moment (M ⃗^((plate) )) exerted by the lunar surface or the VIS plate on the subject’s shoe soles. COP is then calculated from the following equations: r_x^((cop) )= M_z^((plate) )/F_y^((plate) ) and r_z^((cop) )= 〖-M〗_x^((plate) )/F_y^((plate) ), where the y axis is normal to the surface. COP accuracy for feasibility assessments is then determined by whether it falls within the BOS, which is also computed by the plugin. To study the accuracy of COP calculated from motion capture, we first investigated whether COP remained within the BOS, as it must, for exercises performed in the 1g lab environment. Standard exercises such as back squat and deadlift were analyzed, as well as more explosive exercises including hang clean and press. Cases in which the COP exited the BOS indicated that COP accuracy required further investigation. In this study, an exercise device with cables was used, so cable force modeling accuracy should also be considered. In a separate study, we collected motion capture and force plate data for twenty-seven motions not involving an exercise device. About a third were genuine countermeasures exercises (e.g., hang clean and press), some were relevant for lunar tasks (e.g., object pick up), and the rest were of a “unit test” nature (e.g., swaying back and forth or side to side). Motion capture-based COP positions were compared with force plate measured COP. We found that while force plate measured COP remained within the BOS, motion capture-based COP was observed to briefly exit the BOS on occasion. Techniques to mitigate IK artifacts and filtering of calculated data could be used to improve the agreement of calculated and measured results, resolving excursions from the BOS within this dataset. The mean error between calculated and measured COP was found to be less than 6 mm. Additionally, we derived and investigated equations for the COP in terms of the cable force, cable location, as well as the human CM position, acceleration, and angular momentum with respect to the CM, and analyzed them for sensitivity to errors in individual quantities. Several were found, but the most significant one was that when the vertical force on the feet approaches zero, indicating a near-detachment or ‘jump off’ condition, errors are amplified. This is consistent with the observation that in the absence of pressure, the concept of the center of pressure would become meaningless.

C A Bell↗

Flow Boiling and Condensation Experiment (FBCE): Summary of Findings for Flow Boiling based on Completed ISS Experiments

Since 2011, researchers from Purdue University and NASA Glenn Research Center (GRC) have been collaborating to investigate the effects of gravity on several aspects of flow boiling and flow condensation. This massive research endeavor, termed the Flow Boiling and Condensation Experiment (FBCE), has culminated in development of NASA’s largest and most complex facility for investigation of two-phase fluid physics onboard the ISS. FBCE consists of two separate studies: flow boiling, using the Flow Boiling Module (FBM), and flow condensation, using the Condensation Module for Heat Transfer Measurements (CM-HT); this presentation concerns the FBM portion of FBCE. Fitted with FBM, FBCE was launched to the ISS in August 2021 and experiments were successfully performed starting in February 2022 to amass a large microgravity-flow-boiling database supported by extensive visualization of interfacial behavior using high-speed video. Based on FBCE experiments performed previously in Earth gravity and parabolic flight, along with the new ISS data, several empirical correlations, theoretical models, and CFD models have been developed, enabling the prediction of crucial flow boiling parameters, including heat transfer coefficient and critical heat flux (CHF). These predictive tools, which will be summarized in this presentation, are expected to serve as foundation for design of future space systems involving flow boiling.

Two-phase flow and phase transition↗

Sensorimotor adaptations to microgravity in humans

Motor function is altered by microgravity, but little detail is available as to what these changes are and how changes in the individual components of the sensorimotor system affect the control of movement. Further, there is little information on whether the changes in motor performance reflect immediate or chronic adaptations to changing gravitational environments. To determine the effects of microgravity on the neural control properties of selected motor pools, four male astronauts from the NASA STS-78 mission performed motor tasks requiring the maintenance of either ankle dorsiflexor or plantarflexor torque. Torques of 10 or 50% of a maximal voluntary contraction (MVC) were requested of the subjects during 10 degrees peak-to-peak sinusoidal movements at 0.5 Hz. When 10% MVC of the plantarflexors was requested, the actual torques generated in-flight were similar to pre-flight values. Post-flight torques were higher than pre- and in-flight torques. The actual torques when 50% MVC was requested were higher in- and post-flight than pre-flight. Soleus (Sol) electromyographic (EMG) amplitudes during plantarflexion were higher in-flight than pre- or post-flight for both the 10 and 50% MVC tasks. No differences in medial gastrocnemius (MG) EMG amplitudes were observed for either the 10 or 50% MVC tasks. The EMG amplitudes of the tibialis anterior (TA), an antagonist to plantarflexion, were higher in- and post-flight than pre-flight for the 50% MVC task. During the dorsiflexion tasks, the torques generated in both the 10 and 50% MVC tasks did not differ pre-, in- and post-flight. TA EMG amplitudes were significantly higher in- than pre-flight for both the 10 or 50% MVC tasks, and remained elevated post-flight for the 50% MVC test. Both the Sol and MG EMG amplitudes were significantly higher in-flight than either pre- or post-flight for both the 10 and 50% MVC tests. These data suggest that the most consistent response to space flight was an elevation in the level of contractions of agonists and antagonists when attempting to maintain constant torques at a given level of MVC. Also, the chronic levels of EMG activity in selected ankle flexor and extensor muscles during space flight and during routine activities on Earth were recorded. Compared with pre- and post-flight values, there was a marked increase in the total EMG activity of the TA and the Sol and no change in the MG EMG activity in-flight. These data indicate that space flight, as occurs on shuttle missions, is a model of elevated activation of both flexor and extensor muscles, probably reflecting the effects of programmed work schedules in flight rather than a direct effect of microgravity.

NASA Experiment Number 284036↗

Dendritic solidification under microgravity conditions

The Isothermal Dendritic Growth Experiment is undergoing development in cooperation with NASA-Lewis in order to test dendritic growth theory at small supercoolings in low earth orbit. The apparatus encompasses four major subsystems: a temperature-controlled thermostatic bath capable of millikelvin stability, a photographic data collection system, a crystal-growth chamber, and a start-detection system which initiates data collection. Comparisons are made with ground-based study methods for dendritic growth.

Glicksman, M. E.↗

Morphology of human embryonic kidney cells in culture after space flight

The ability of human embyronic kidney cells to differentiate into small epithelioid, large epithelioid, domed, and fenestrated morphological cell types following space flight is examined. Kidney cells exposed to 1 day at 1 g, then 1 day in orbit, and a 12 minute passage through the electrophoretic separator are compared with control cultures. The data reveal that 70 percent of small epithelioid, 16 percent of large epithelioid, 9 percent of dome-forming, and 5 percent of fenestrated cells formed in the space exposed cells; the distributions correlate well with control data. The formation of domed cells from cells cultured from low electrophoretic mobility fractions and small epithelioid cells from high mobility fractions is unaffected by space flight conditions. It is concluded that storage under microgravity conditions does not influence the morphological differentiation of human embryonic kidney cells in low-passage culture.

Todd, P.↗