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All sourcesNASA NTRSDOE OSTI
DOE OSTI2020

Spirometric traits show quantile-dependent heritability, which may contribute to their gene-environment interactions with smoking and pollution

Background: “Quantile-dependent expressivity” refers to a genetic effect that is dependent upon whether the phenotype (e.g., spirometric data) is high or low relative to its population distribution. Forced vital capacity (FVC), forced expiratory volume in 1 second (FEV 1 ), and the FEV 1 /FVC ratio are moderately heritable spirometric traits. The aim of the analyses is to test whether their heritability (h 2 ) is constant over all quantiles of their distribution. Methods: Quantile regression was applied to the mean age, sex, height and smoking-adjusted spirometric data over multiple visits in 9,993 offspring-parent pairs and 1,930 sibships from the Framingham Heart Study to obtain robust estimates of offspring-parent (β OP ), offspring-midparent (β OM ), and full-sib regression slopes (β FS ). Nonparametric significance levels were obtained from 1,000 bootstrap samples. β OP s were used as simple indicators of quantile-specific heritability (i.e.,h 2 = 2β OP /(1+r spouse ), where r spouse was the correlation between spouses). Results: β OP ± standard error (SE) decreased by 0.0009 ± 0.0003 (P = 0.003) with every one-percent increment in the population distribution of FEV 1 /FVC, i.e., β OP ± SE were: 0.182 ± 0.031, 0.152 ± 0.015; 0.136 ± 0.011; 0.121 ± 0.013; and 0.099 ± 0.013 at the 10th, 25th, 50th, 75th, and 90th percentiles of the FEV 1 /FVC distribution, respectively. These correspond to h 2 ± SEs of 0.350 ± 0.060 at the 10th, 0.292 ± 0.029 at the 25th, 0.262 ± 0.020 at the 50th, 0.234 ± 0.025 at the 75th, and 0.191 ± 0.025 at the 90th percentiles of the FEV 1 /FVC ratio. Maximum mid-expiratory flow (MMEF) h 2 ± SEs increased 0.0025 ± 0.0007 (P = 0.0004) with every one-percent increment in its distribution, i.e.: 0.467 ± 0.046, 0.467 ± 0.033, 0.554 ± 0.038, 0.615 ± 0.042, and 0.675 ± 0.060 at the 10th, 25th, 50th, 75th, and 90th percentiles of its distribution. This was due to forced expiratory flow at 75% of FVC (FEF75%), whose quantile-specific h 2 increased an average of 0.0042 ± 0.0008 for every one-percent increment in its distribution. It is speculated that previously reported gene-environment interactions may be partially attributable to quantile-specific h 2 , i.e., greater heritability in individuals with lower FEV 1 /FVC due to smoking or airborne particles exposure vs. nonsmoking, unexposed individuals. Conclusion: Heritabilities of FEV 1 /FVC, MMEF, and FEF75% from quantile-regression of offspring-parent and sibling spirometric data suggest their quantile-dependent expressivity.

59 BASIC BIOLOGICAL SCIENCES↗
NASA NTRS1971

Vertical resolution of temperature profiles obtained from remote radiation measurements

The Backus-Gilbert theory is applied to the problem of the vertical sounding of the atmosphere by means of remote radiation measurements. An application is made to spectral intervals 2.8/cm wide in the 667/cm band of CO2, and tradeoff curves are presented which quantitatively define the relationship between intrinsic vertical resolution and random error in temperature profile estimates. It is found that for a 1-2K random error with state-of-the-art instrumentation, the intrinsic vertical resolution ranges from approximately 0.5 local scale height (l.s.h.) in the lower troposphere to 2 l.s.h. in the upper stratosphere with approximately 2 l.s.h. resolution in the vicinity of the tropopause. These values are somewhat smaller than the widths of the radiactive transfer kernels at similar levels. Increasing the number of spectral intervals from 7 to 16 is found to produce only a marginal improvement in vertical resolution.

Conrath, B. J.↗
NASA NTRS1971

Vertical resolution of temperature profiles obtained from remote radiation measurements

The Backus-Gilbert theory, originally developed for analysis of inversion problems associated with the physics of the solid earth, was applied to the problem of the vertical sounding of the atmosphere by means of remote radiation measurements. An application was made to spectral intervals 2.8/cm wide in the 667/cm band CO2, and tradeoff curves are presented which quantitatively define the relationship between intrinsic vertical resolution and random error in temperature profile estimates. It is found that for a 1-2 K random error with state-of-the-art instrumentation, the intrinsic vertical resolution ranges from approximately 0.5 locale scale height (l.s.h.) in the lower troposphere to greater than 2 l.s.h. in the upper stratosphere with approximately 1 l.s.h. resolution in the vicinity of the tropopause. These values are somewhat smaller than the widths of the radioactive transfer kernels at similar levels. Increasing the number of spectral intervals from 7 to 16 is found to produce only a marginal improvement in vertical resolution.

Conrath, B. J.↗
NASA NTRS1981

On the birthrate of galactic supernovae

The birthrate of galactic supernovae is estimated in three different ways. The three ranges overlap, and it is suggested that 70 + or - 35 yr represents a more realistic estimate of the rate than some that have previously been made. The galactic supernova remnants and their observed systematic brightness gradients perpendicular to the galactic plane imply a scale height of about 200 pc for the remnant progenitors and a galactic magnetic field scale height of about 300 pc. Long standing anomalies associated with the young remnant AD 1006, the galactic loops, and faint remnants, are accounted for by the brightness gradient effect. This provides firm, independent evidence for the validity of the remnant method of deducing the birthrate of galactic supernovae.

Lerche, I.↗
NASA NTRS1990

SR90, strontium shaped-charge critical ionization velocity experiment

In May 1986 an experiment was performed to test Alfven's critical ionization velocity (CIV) effect in free space, using the first high explosive shaped charge with a conical liner of strontium metal. The release, made at 540 km altitude at dawn twilight, was aimed at 48 deg to B. The background electron density was 1.5 x 10(exp 4) cu cm. A faint field-aligned Sr(+) ion streak with tip velocity of 2.6 km/s was observed from two optical sites. Using two calibration methods, it was calculated that between 4.5 x 10(exp 20) and 2 x 10(exp 21) ions were visible. An ionization time constant of 1920 s was calculated for Sr from the solar UV spectrum and ionization cross section which combined with a computer simulation of the injection predicts 1.7 x 10(exp 21) solar UV ions in the low-velocity part of the ion streak. Thus all the observed ions are from solar UV ionization of the slow (less than critical) velocity portion of the neutral jet. The observed neutral Sr velocity distribution and computer simulations indicate that 2 x 10(exp 21) solar UV ions would have been created from the fast (greater than critical) part of the jet. They would have been more diffuse, and were not observed. Using this fact it was estimated that any CIV ions created were less than 10(exp 21). It was concluded that future Sr CIV free space experiments should be conducted below the UV shadow height and in much larger background plasma density.

Wescott, Eugene M.↗
NASA NTRS2010

Application of the Tor Vergata Scattering Model to L Band Backscatter During the Corn Growth Cycle

At the USDA's Optimizing Production Inputs for Economic and Environmental Enhancement (OPE3) experimental site in Beltsville, Maryland, USA) a field campaign took place throughout the 2002 corn growth cycle from May 10th (emergence of corn crops) to October 2nd (harvest). One of the microwave instruments deployed was the multi-frequency (X-, C- and L-band) quad-polarized (HH, HV, VV, VH) NASA GSFC/George Washington University (GWU) truck mounted radar. During the field campaign, this radar system provided once a week fully polarized C- and L-band (4.75 and 1.6 GHz) backscatter measurements from incidence angle of 15, 35, and 55 degrees. In support of microwave observations, an extensive ground characterization took place, which included measurements of surface roughness, soil moisture, vegetation biomass and morphology. The field conditions during the campaign are characterized by several dry downs with a period of drought in the month of August. Peak biomass the corn canopies was reached on July 24th with a total biomass of approximately 6.5 kg/sq m. This dynamic range in both soil moisture and vegetation conditions within the data set is ideal for the validation of discrete medium vegetation scattering models. In this study, we compare the L band backscatter measurements with simulations by the Tor Vergata model (ferrazzoli and Guerriero 1996). The measured soil moisture, vegetation biomass and most reliably measured vegetation morphological parameters (e.g. number of leaves, number of stems and stem height) were used as input for the Tor Vergata model. The more uncertain model parameters (e.g. surface roughness, leaf thickness) and the stem diameter were optimized using a parameter estimation routine based on the Levenberg-Marquardt algorithm. As cost function for this optimization, the HH and VV polarized backscatter measured and stimulated by the TOR Vergata model for incidence angle of 15, 35, and 55 degrees were used (6 measurements in total). The calibrated Tor Vergata model simulations are in excellent agreement with the measurements of Root Mean Squared Differences (RMSD's) of 0.8, 0.9 and 1.4 dB for incidences of 15, 35 and 55 degrees, respectively. The results from this study that a physically based scattering model with the appropriate parameterization can accurately simulate backscatter measurements and, as such, have the potential of being used for the retrieval of biophysical variables (e.g. soil moisture and vegetation biomass).

Joseph, A. T.↗
NASA NTRS2014

Deciphering the Precision of Stereo IKONOS Canopy Height Models for U.S. Forests with G-LiHT Airborne LiDAR

Few studies have evaluated the precision of IKONOS stereo data for measuring forest canopy height. The high cost of airborne light detection and ranging (LiDAR) data collection for large area studies and the present lack of a spaceborne instrument lead to the need to explore other low cost options. The US Government currently has access to a large archive of commercial high-resolution imagery, which could be quite valuable to forest structure studies. At 1 m resolution, we here compared canopy height models (CHMs) and height data derived from Goddard's airborne LiDAR Hyper-spectral and Thermal Imager (G-LiHT) with three types of IKONOS stereo derived digital surface models (DSMs) that estimate CHMs by subtracting National Elevation Data (NED) digital terrain models (DTMs). We found the following in three different forested regions of the US after excluding heterogeneous and disturbed forest samples: (1) G-LiHT DTMs were highly correlated with NED DTMs with R (sup 2) greater than 0.98 and root mean square errors (RMSEs) less than 2.96 m; (2) when using one visually identifiable ground control point (GCP) from NED, G-LiHT DSMs and IKONOS DSMs had R (sup 2) greater than 0.84 and RMSEs of 2.7 to 4.1 m; and (3) one GCP CHMs for two study sites had R (sup 2) greater than 0.7 and RMSEs of 2.6 to 3 m where data were collected less than four years apart. Our results suggest that IKONOS stereo data are a useful LiDAR alternative where high-quality DTMs are available.

IKONOS↗
NASA NTRS1996

Design considerations of GeoSAR

The primary purpose of GeoSAR is to demonstrate the feasibility of interferometric topographic mapping through foliage penetration. GeoSAR should become a commercially viable instrument after the feasibibility demonstration. To satisfy both requirements, we have designed a dual frequency (UHF- and X-band) interferometric radar. For foliage penetration, a lower frequency (UHF)radar is used. To obtain better height accuracy for low backscatter areas, we proposed a high frequency (X-band) interferometric system. In this paper, we present a possible GeoSAR system configuration and associated performance estimation.

GeoSAR↗
NASA NTRS1995

Sea surface topography fields of the tropical Pacific from data assimilation

Time series of maps of monthly tropical Pacific dynamic topography anomalies from 1979 through 1985 were constructed by means of assimilation of the tide gauge and expendable bathythermograph (XBT) data into a linear model driven by observed winds. Estimates of error statistics were calculated and compared to actual differences between hindcasts and observations. Four experiements were performed as follows: one with no assimilation, one with assimiation of sea level anomaly data from eight selected island tide gauge stations, one with assimilation of dynamic height anomalies derived from XBT data, and one with both XBT and tide gauge data assimilated. Data from seven additional tide gauge stations were withheld from the assimilation process and used for verification in all four experiements. Statistical objective maps based on data alone were also constructed for comparison purposes. The dynamic response of the model without assimilation was, in general, weaker than the observed response. Assimilation resulted in enhanced signal amplitude in all three assimilation experiments. With few exceptions the error estimated generated by the Kalman filter appeared quite reasonable. Since the error processes cannot be assumed to be white or stationary, we could find no straightforward way to test the formal statistical hypothesis that the time series of differences between the filter ouput and the actual observations were drawn from a population with statistics given by the Kalman filter estimaes. We found that the best filter we could devise was still short of the goal of producing a white innovation sequence. Extensive changes in the assumed error statistics make only marginal differences. The same is true for long time and space scale behavior of different models with richer physics and finer resolution. Better data assimilation results will probably require relaxation of the assumptions of stationarity and serial independence of the errors. Formation of such detailed noise models will require longer time series, with the attendant problems of matching very different data sets.

Miller, Robert N.↗
NASA NTRS1977

A comparison of several methods of estimating the columnar electron content of the plasmasphere

Data from several different observation techniques are used to estimate the columnar electron content of the plasmasphere. The estimate is based upon the subtraction of the ionospheric electron content from the total content along the radio path from ground to the geostationary satellite ATS-6. The Radio Beacon Experiment on this satellite allows a very accurate determination of the total electron content up to the height of the satellite. For the ionospheric electron content (ground to appr. 2000 km) the following techniques are used: (1) Faraday effect on the ATS-6 signals, (2) differential Doppler effect on the signals of the low-orbiting NNSS satellites, (3) combination of bottomside and topside ionograms, and (4) extrapolation of bottomside ionograms. It is shown that the combination of group delay and Faraday effect data on the ATS-6 RBE signals provide the most reliable estimates of the columnar electron content of the plasmasphere. Data from low-orbiting satellites support this conclusion.

Davies, K.↗
NASA NTRS1988

A modified ATI technique for nowcasting convective rain volumes over areas

This paper explores the applicability of the area-time-integral (ATI) technique for the estimation of the growth portion only of a convective storm (while the rain volume is computed using the entire life history of the event) and for nowcasting the total rain volume of a convective system at the stage of its maximum development. For these purposes, the ATIs were computed from the digital radar data (for 1981-1982) from the North Dakota Cloud Modification Project, using the maximum echo area (ATIA) no less than 25 dBz, the maximum reflectivity, and the maximum echo height as the end of the growth portion of the convective event. Linear regression analysis demonstrated that correlations between total rain volume or the maximum rain volume versus ATIA were the strongest. The uncertainties obtained were comparable to the uncertainties which typically occur in rain volume estimates obtained from radar data employing Z-R conversion followed by space and time integration. This demonstrates that the total rain volume of a storm can be nowcasted at its maximum stage of development.

Makarau, Amos↗
NASA NTRS1988

Sedimentological effects of tsunamis, with particular reference to impact-generated and volcanogenic waves

Impulse-generated waves (tsunamis) may be produced, at varying scales and global recurrence intervals (RI), by several processes. Meteorite-water impacts will produce tsunamis, and asteroid-scale impacts with associated mega-tsunamis may occur. A bolide-water impact would undoubtedly produce a major tsunami, whose sedimentological effects should be recognizable. Even a bolide-land impact might trigger major submarine landslides and thus tsunamis. In all posulated scenarios for the K/T boundary event, then, tsunamis are expected, and where to look for them must be determined, and how to distinguish deposits from different tsunamis. Also, because tsunamis decrease in height as they move away from their source, the proximal effects will differ by perhaps orders of magnitude from distal effects. Data on the characteristics of tsunamis at their origin are scarce. Some observations exist for tsunamis generated by thermonuclear explosions and for seismogenic tsunamis, and experimental work was conducted on impact-generated tsunamis. All tsunamis of interest have wave-lengths of 0(100) km and thus behave as shallow-water waves in all ocean depths. Typical wave periods are 0(10 to 100) minutes. The effect of these tsunamis can be estimated in the marine and coastal realm by calculating boundary shear stresses (expressed as U*, the shear velocity). An event layer at the K/T boundary in Texas occurs in mid-shelf muds. Only a large, long-period wave with a wave height of 0(50) m, is deemed sufficient to have produced this layer. Such wave heights imply a nearby volcanic explosion on the scale of Krakatau or larger, or a nearby submarine landslide also of great size, or a bolide-water impact in the ocean.

Bourgeois, Joanne↗
NASA NTRS1999

The Role of Orograph and Parallax Corrections on High Resolution Geostationary Satellite Rainfall Estimates for Flash Flood Applications

The current generation of geosynchronous satellites exhibits considerably improved capabilities in the area of resolution, gridding accuracy, and sampling frequency as compared to their predecessors. These improvements have made it possible to accurately observe the life cycle of small scale, short-live phenomenon like rapidly developing thunderstorms, at a very high spatial and temporal resolutions. While the gain in the improved resolution is not significant for synoptic scale cloud systems, it plays a major role on the computation of precipitation values for mesoscale and stonn scale systems. Two of the important factor on the accurate precision of precipitation from satellite imagery are the position of the cloud tops as viewed by the satellite and the influence of orographic effects on the distribution of precipitation. The first problem has to do with the fact that the accurate estimation of precipitation from data collected by a satellite in geosynchronous orbit requires the knowledge of the exact position of the cloud tops with respect to the ground below. This is not a problem when a cloud is located directly below the satellite; at large viewing angles the geographic coordinates on satellite images are dependent on cloud heights and distance from the sub-satellite point. The latitude and longitude coordinates for high convective cloud tops are displaced away from the sub-satellite point and may be shifted by as much as 20 Km from the sea level coordinates. The second problem has to do with the variations in rainfall distribution with elevation. Ground observations have shown that precipitation amounts tend to increase with height and that the slope of the hill or mountain that is facing the prevailing wind normally receives greater rainfall then do the lee slopes. The purpose of the study is to show the recent developments at the Office of Research and Applications (ORA) at the National Oceanic and Atmospheric Administration (NOAA/NESDIS) in Camp Springs, MD, USA, to adjust any satellite rainfall estimation technique and account for orographic and parallax corrections. Description and examples of the procedure applied to the current NOAA/NESDIS experimental satellite rainfall estimation technique for flash flood applications will be presented at the conference.

Vicente, Gilberto A.↗
NASA NTRS2019

Simultaenous Retrieval of Surface Roughness Parameters from Combined Active-Passive SMAP Observations

Soil roughness strongly influences processes like erosion, infiltration, moisture and evaporation of soils as well as growth of agricultural plants. An approach to soil roughness based on active-passive microwave covariation is proposed in order to simultaneously retrieve the vertical RMS height (s) and horizontal correlation length (l) of soil surfaces from simultaneously measured radar and radiometer microwave signatures. The approach is based on a retrieval algorithm for active-passive covariation including the improved Integral Equation Method (I2EM). The algorithm is tested with the global active-passive microwave observations of the SMAP mission. The developed roughness retrieval algorithm shows independence of permittivity for > 10 [-] due to the covariation formalism. Results reveal that s and l can be estimated simultaneously by the proposed approach since surface patterns of non-vegetated areas become evident on global scale. In regions with sandy deserts, like the Sahara or the outback in Australia, determined and confirm rather smooth to semi-rough surface roughness patterns with small vertical RMS heights and corresponding higher horizontal correlation lengths.

correlation length↗
NASA NTRS2009

Studies of a Space Lidar Instrument for the ASCENDS Mission

We have developed a lidar technique for measuring the tropospheric C02 concentrations as a candidate for NASA's planned ASCENDS mission. Our technique uses two pulsed laser transmitters allowing simultaneous measurement of a C02 absorption line in the 1570 nm band, 02 extinction in the Oxygen A-band and surface height and backscatter. The lidar measures the energy and time of flight of the laser echoes reflected from the atmosphere and surface. The lasers are stepped in wavelength across the C02 line and an 02 line region during the measurement. The receiver uses a telescope and photon counting detectors, and measures the background light and energies of the laser echoes from the surface along with scattering from any aerosols in the path. The gas extinction and column densities for the C02 and 02 gases are estimated from the ratio of the on- and off- line signals via the DIAL technique. Pulsed laser signals and a time gated receiver are used to isolate the laser echo signals from the surface, to reject laser photons scattered in the atmosphere, and measure the surface height and scattering profile in the path. We have recently completed a second design study for the space instrument. For the study, we selected a nominal sun-synchronous orbit with an altitude of 400 km and equator crossing time of 1:30 pm, and a receiver telescope with 1.5 m diameter.

Abshire, J. B.↗
NASA NTRS1981

Vertical extensions of galactic spiral arms

The vertical structure of the large scale galactic shock along spiral arms is studied in order to understand the extended features or the wings of spiral arms observed by Kepner (1970) and recently checked by Soukup (1979). Numerical calculations of two-dimensional gas flow were performed for two models of the gas. The results show that the shock front, standing perfectly perpendicular to the galactic plane, extends impressively above the scale height of the interstellar gas. In the extreme case of isothermal gas, the shock solution exists at any distance from the plane. In a realistic model in which the kinetic temperature of the gas is stratified, increasing with height, the shock can extend up to 700 pc. For both models, although the velocity component perpendicular to the galactic plane is small, the solutions corresponding to layered one-dimensional flow contain no shocks at such heights. In order to study the geometry of the shock front and the flow pattern near it, a simplified model is adopted, in which the Coriolis force is neglected. However, estimates show that including it will enhance the shock strength. The compression at the shock front makes the gas observable at high latitudes.

Soukup, J. E.↗
NASA NTRS1985

The extent of the local hi halo

Forty-five high-latitude, OB stars have been observed in the Ly alpha and 21 cm lines of HI in an effort to map out the vertical distribution and extent of the local HI halo. The 25 stars for which a reliable HI colum density can be obtained from Ly alpha lie between 60 and 3100 pc from the plane. The principal result is that the total column density of HI at z 1 kpc is, on the average, 5 + or - 3 x 10 the 19th power/sq cm, or 15% of the total sub HI. At relatively low z the data toward some stars suggest a low effective scale height and fairly high average foreground density, while toward others the effective scale height is large and the average density is low. This can be understood as the result of irregularities in the interstellar medium. A model with half of the HI mass in clouds having radii of a few pc and a Gaussian vertical distribution with sigma sub 2 = 135 pc, and half of the mass in an exponential component with a scale height of 500 pc, gives a satisfactory fit to the data. The technique of comparing Ly alpha and 21 cm column densities is also used to discuss the problem of estimating the distance to several possibly subluminous stars.

Lockman, F. J.↗
NASA NTRS1986

The extent of the local H I halo

Forty-five high-latitude, OB stars have been observed in the Ly alpha and 21 cm lines of HI in an effort to map out the vertical distribution and extent of the local HI halo. The 25 stars for which a reliable HI column density can be obtained from Ly alpha lie between 60 and 3100 pc from the plane. The principal result is that the total column density of HI at an absolute value of z greater than 1 kpc is, on the average, 5 + or - 3 x 10 to the 19th power/sq cm, or 15 percent of the total sub HI. At relatively low z the data toward some stars suggest a low effective scale height and fairly high average foreground density, while toward others the effective scale height is large and the average density is low. This can be understood as the result of irregularities in the interstellar medium. A model with half of the HI mass in clouds having radii of a few pc and a Gaussian vertical distribution with sigma sub 2 = 135 pc, and half of the mass in an exponential component with a scale height of 500 pc, gives a satisfactory fit to the data. The technique of comparing Ly alpha and 21 cm column densities is also used to discuss the problem of estimating the distance to several possibly subluminous stars.

Lockman, F. J.↗