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At least 973 records · Page 54

Capturing Complex Multivariate Time Series Interactions to Detect High-Risk Adverse Events During Flight

The reduction of aviation safety metrics below target thresholds continue to drive down the number of aviation fatalities and accidents. To meet future safety demands, sustained efforts by aviation agencies promoting safety assurance processes and systems have prompted ongoing research on identifying and mitigating in-flight risks. With the projected increase in passenger load factor and rollout of more autonomous systems into the national airspace, the need to detect high-risk events in-time or ahead-of-time is becoming increasingly crucial. New anomaly detection and precursor identification algorithms will need to scale to different airframes, levels of autonomy, and system complexity. While the pervasiveness of deep learning has resulted in the development of performant anomaly detection methods, these sophisticated models currently suffer from low end-user interpretability. Building off our previous work on identifying adverse events in multivariate flight data during descent, we propose a data-driven approach for detecting in-flight adverse events caused by the complex interplay of flight variables. Our approach utilizes ordinal patterns of important aircraft stability variables (e.g., airspeed and descent rate) to capture multivariate flight dynamics that can be used to predict the onset of unstable approaches, a high-risk adverse event that can occur during approach. Through the use of ordinal patterns, we aim to create more interpretable detection models of in-flight adverse events that can be translated to future autonomous systems without difficulty. Our analysis shows the presence of distinct ordinal pattern distributions that can be used to predict unstable approaches 1 minute ahead of time with an accuracy of 0.69 and a recall of 0.73 and 30 seconds ahead with an accuracy of 0.70 and a recall of 0.86.

Risk detection↗

Capturing Multivariate Time Series Interactions to Detect High‑Risk Instability During Approach

The reduction of aviation safety metrics below target thresholds continue to drive down the number of aviation fatalities and accidents. To meet future safety demands, sustained efforts by aviation agencies promoting safety assurance processes and systems have prompted ongoing research on identifying and mitigating in-flight risks. With the projected increase in passenger load factor and rollout of more autonomous systems into the national airspace, the need to detect high-risk events in-time or ahead-of-time is becoming increasingly crucial. New anomaly detection and precursor identification algorithms will need to scale to different airframes, levels of autonomy, and system complexity. While the pervasiveness of deep learning has resulted in the development of performant anomaly detection methods, these sophisticated models currently suffer from low end-user interpretability. Building off our previous work on identifying adverse events in multivariate flight data during descent, we propose a data-driven approach for detecting in-flight adverse events caused by the complex interplay of flight variables. Our approach utilizes ordinal patterns of important aircraft stability variables (e.g., airspeed and descent rate) to capture multivariate flight dynamics that can be used to predict the onset of unstable approaches, a high-risk adverse event that can occur during approach. Through the use of ordinal patterns, we aim to create more interpretable detection models of in-flight adverse events that can be translated to future autonomous systems without difficulty. Our analysis shows the presence of distinct ordinal pattern distributions that can be used to predict unstable approaches 1 minute ahead of time with an accuracy of 0.69 and a recall of 0.73 and 30 seconds ahead with an accuracy of 0.70 and a recall of 0.86.

Risk detection↗

Performance of an RPM based on Gd-lined plastic scintillator for neutron and gamma detection [ANIMMA--2015-IO-372]

A Radiation Portal Monitor (RPM) was developed by the Istituto Nazionale di Fisica Nucleare (INFN) and Ansaldo Nucleare (ANN) within the FP7 SCINTILLA European project. The system was designed to detect both gamma and neutron radiation with a single technology. It is conceived to monitor vehicle and cargo containers in transits across borders or ports, to find radioactive elements and to avoid illegal trafficking of strategic nuclear materials. The system is based on a {sup 3}He-free neutron detection technology using plastic scintillators coupled to Gadolinium to detect and discriminate gamma from neutron signals. During the 3 years of the SCINTILLA project the construction and test of the first two prototypes drove the definition of the final layout of a full RPM system consisting of two twin pillars as a portal for vehicle and cargo container scan. A custom System Control Software (SCS) manages the electronics of the RPM, the ancillary devices and the data analysis. The combination of the detector layout and of the software functionalities enables both to distinguish neutrons and gammas and to identify the energy range of a detected gamma source. The system was initially characterized via static tests with gamma and neutron sources in the INFN laboratory. These measurements were used to calibrate the detector, evaluate the response of the single pillars as well as of the full system, and optimize the RPM configuration and discrimination algorithm. During this phase, specific tests were performed to study the stability over time of the system, monitoring the measured the neutron and gamma count rates over periods of several weeks. The results allow us to demonstrate the reliability and robustness of the RPM. In a second time the RPM performance was studied via dynamic tests performed during the SCINTILLA test and benchmark campaigns. These measurements took place in the JRC ITRAP+10 facility at Ispra (Varese-Italy). The laboratory is equipped with an experimental set-up for dynamic tests of multiple systems according to international standards. The performed measurements utilized radioactive sources with activities selected according to ANSI and IEC standards to test the detector alarm performances in terms of gamma and neutron response, sensitivity to high gamma fields, sensitivity to moderated neutron sources as well as false alarm rates (FAR). In addition, the RPM was tested in challenging configurations exceeding the requirements set by international standards to determine the real limits of the system. The results obtained during these campaigns demonstrated that the system detection efficiency is not only compliant to international standards for its category, but often exceeds them, demonstrating the validity of the chosen technology and of the implemented layout. The positive performance also showed the effectiveness of the SCS and of its functionalities. To further demonstrate the system capabilities, a test in a real-life environment of the RPM is planned to happen in a near future by installing the detectors in a seaport. In this presentation I will give an overview of the RPM characteristics, of its performances as determined in the test campaign mentioned above and of future plans, to demonstrate how this technology can be an effective choice for the realization of {sup 3}He-free RPM detectors. (authors)

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Detection Of Special Nuclear Materials Tagged Neutrons

In order to detect Special Nuclear Materials (SNM) in unattended luggage or cargo containers in the field of homeland security, fissions are induced by 14 MeV neutrons produced by an associated particle DT neutron generator, and prompt fission particles correlated with tagged neutron are detected by plastic scintillators. SMN produce high multiplicity events due to induced fissions, whereas nonnuclear materials produce low multiplicity events due to cross-talk, (n,2n) or (n,n'γ) reactions. The data acquisition electronics is made of compact FPGA boards. The coincidence window is triggered by the alpha particle detection, allowing to tag the emission date and direction of the 14 MeV interrogating neutron. The first part of the paper presents experiment vs. calculation comparisons to validate MCNP-PoliMi simulations and the post-processing tools developed with the data analysis framework ROOT. Measurements have been performed using different targets (iron, lead, graphite), first with small plastic scintillators (10 x 10 x 10 cm{sup 3}) and then with large detectors (10 x 10 x 100 cm{sup 3}) to demonstrate that nuclear materials can be differentiated from nonnuclear dense materials (iron, lead) in iron and wood matrixes. A special attention is paid on SNM detection in abandoned luggage. In the second part of the paper, the performances of a cargo container inspection system are studied by numerical simulation, following previous work reported in. Detectors dimensions and shielding against the neutron generator background are optimized for container inspection. Events not correlated to an alpha particle (uncorrelated background), counting statistics, time and energy resolutions of the data acquisition system are all taken into account in a realistic numerical model. The impact of the container matrix (iron, ceramic, wood) has been investigated by studying the system capability to detect a few kilograms of SNM in different positions in the cargo container, within 10 min acquisitions. (authors)

36 MATERIALS SCIENCE↗

Automated Label‐Free Assay for Viral Detection and Inhibitor Screening via Biomembrane‐Functionalized Microelectrode Arrays

Most virus infection assays have indirect readout such as virus number following entry (e.g., PCR, cell lysis). While effective, these technologies are labor‐intensive, require specialized environments (e.g., sterile or RNA‐free), and detect later‐stage viral events like lysis or cell death, lacking sensitivity to early fusion events. To address these limitations, we present biologically relevant 2D membrane materials, host‐cell‐derived supported lipid bilayers (hcd‐SLBs), integrated with organic microelectrode arrays (OMEAs) for detection of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) fusion. By overexpressing angiotensin‐converting enzyme 2 (ACE2) receptors on the native membranes, the platform functions as a viral sensor capable of detecting virus pseudo particles (VPPs) through the late pathway. Additionally, hcd‐SLBs extracted from human lung epithelium expressing native ACE2 detect fusion events through the early pathway. The platform's utility as a drug‐screening tool is demonstrated by testing antibodies targeting either the ACE2 on the host membrane or the viral spike (S) proteins. To enhance the throughput, microfluidics are integrated for automation and OMEAs are incorporated within each channel, miniaturizing the testing units. This system supports high‐throughput data generation, automation, and scalability, providing an efficient platform for viral fusion detection that advances the study of pathogen‐host interactions and accelerates antiviral drug discovery.

Biology↗

Automated Fire Detection for Industrial Settings with Pretrained Convolutional Networks

Early fire detection in industrial environments is critical to preventing equipment damage, personal injury, and operational disruptions. Traditional smoke detectors, while effective, often experience delays due to the time required for smoke to reach sensors, allowing fires to spread. Manual fire watch operations and human surveillance of camera feeds are resource-intensive and prone to human error. To address these challenges, this paper explores the application of convolutional neural networks for automated fire detection, specifically in industrial settings. By leveraging 11 different pre-trained machine vision models from TensorFlow and enhancing them with transfer learning on a custom-built industrial fire dataset, we optimized fire detection performance. Here, we analyzed each machine vision model architecture in terms of its depth, width, and input image resolution, considering both resource requirements and detection accuracy. We further explored the option of combining multiple models into an ensemble classifier to evaluate whether the performance improvements could justify the much greater computational complexity and other practical impacts. A cost-benefit analysis is presented to evaluate the trade-offs between performance and computational expense. Our findings identify that EfficientNetV2L, specifically tailored for industrial applications, provides the optimal balance between costs involved in training and using the model versus the overall fire detection performance. Additionally, we present a qualitative analysis of model performance using the technique of gradient-based class activation mapping to provide explainability by visualizing model decisions.

artificial intelligence↗

Exploiting Acoustic Anisotropy to Detect Recrystallization in a Ni Single Crystal Using Ultrasonic Nondestructive Inspection

Ultrasonic inspection was used to detect regions of recrystallization (RX) within a single crystal of Ni. RX can produce polycrystalline regions within single-crystal (SX) materials. Because RX regions act as initiator sites for failure by fatigue-crack growth in otherwise SX Ni-based superalloys, RX is an issue of direct concern for the service life of high-performance turbine blades. Detection and discrimination of RX regions in single-crystal materials are significant challenges for current nondestructive inspection technologies. The present study leverages the elastic anisotropy of single crystals, which produces acoustic anisotropy, to ultrasonically detect and characterize RX regions produced within single-crystal specimens. Single crystals of pure Ni were processed to create controlled regions of RX. These specimens were ultrasonically examined in an immersion tank using a high-resolution, polyvinylidene fluoride transducer to detect acoustic impedance changes across the boundaries between different crystals (i.e., grains) within the RX region. Data from time-of-flight and absolute peak amplitude measurements were used to create acoustic images that were compared against electron microscope images of the RX regions. The ultrasonic inspection technique described here successfully detected not only the locations of RX regions, but also the approximate sizes and shapes of the RX regions.

36 MATERIALS SCIENCE↗

A multi-level anomaly detection algorithm for time-varying graph data with interactive visualization

This work presents a novel modeling and analysis framework for graph sequences which addresses the challenge of detecting and contextualizing anomalies in labelled, streaming graph data. We introduce a generalization of the BTER model of Seshadhri et al. by adding flexibility to community structure, and use this model to perform multi-scale graph anomaly detection. Specifically, probability models describing coarse subgraphs are built by aggregating node probabilities, and these related hierarchical models simultaneously detect deviations from expectation. This technique provides insight into a graph's structure and internal context that may shed light on a detected event. Additionally, this multi-scale analysis facilitates intuitive visualizations by allowing users to narrow focus from an anomalous graph to particular subgraphs or nodes causing the anomaly. For evaluation, two hierarchical anomaly detectors are tested against a baseline Gaussian method on a series of sampled graphs. We demonstrate that our graph statistics-based approach outperforms both a distribution-based detector and the baseline in a labeled setting with community structure, and it accurately detects anomalies in synthetic and real-world datasets at the node, subgraph, and graph levels. Furthermore, to illustrate the accessibility of information made possible via this technique, the anomaly detector and an associated interactive visualization tool are tested on NCAA football data, where teams and conferences that moved within the league are identified with perfect recall, and precision greater than 0.786.

97 MATHEMATICS AND COMPUTING↗

High Mass Ion Detection with Charge Detector Coupled to Rectilinear Ion Trap Mass Spectrometer

Conventional linear ion trap mass analyzers (LIT-MS) provide high ion capacity and show their MS{sup n} ability; however, the detection of high mass ions is still challenging because LIT-MS with secondary electron detectors (SED) cannot detect high mass ions. To detect high mass ions, we coupled a charge detector (CD) to a rectilinear ion trap mass spectrometer (RIT-MS). Immunoglobulin G ions (m/z ~150,000) are measured successfully with controlled ion kinetic energy. In addition, when mass-to-charge (m/z) ratios of singly charged ions exceed 10 kTh, the detection efficiency of CD is found to be greater than that of SED. The CD can be coupled to LIT-MS to extend the detection mass range and provide the potential to perform MS{sup n} of high mass ions inside the ion trap. .

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Anomaly Detection in Materials Digital Twins with Multiscale ICME for Additive Manufacturing

Detecting anomaly in fatigue and fracture experimental materials science is an interesting yet challenging topic. The reasons are threefold. First, the anomalous microstructure feature that gives rise to structural failure is small, sometimes in the order of 10 -7 of the interrogated volume. This, in turn, results in a highly imbalanced classification problem in machine learning (ML). Second, the consequence is high, in the sense that the test specimen is destructed in such case. Third, the convolution between microstructure stochasticity and the small probability of void nucleation, growth, and coalescence makes failure and fracture a hard-to-predict and challenging problem in materials science due to its irreproducibility, even experimentally. In this paper, we developed a materials digital twin and applied anomaly detection methods to detect voids and anomaly in additive manufacturing (AM). The materials digital twin is driven by two integrated computational materials engineering (ICME) models, which are kinetic Monte Carlo (kMC) and crystal plasticity finite element method (CPFEM). In conclusion, we demonstrated that by using anomaly detection, it is possible to detect voids and other defects in materials digital twin, which paves way for future research in integrating materials digital twin with its physical counterpart.

ICME↗

Autonomous anomaly detection of proliferation in the AGN-201 nuclear reactor digital twin

The expansion of global nuclear power necessitates advanced methods for analyzing proliferation indicators. This study introduces a novel application of the Isolation Forest Machine Learning (IFML) algorithm within a digital twin (DT) of the AGN-201 nuclear reactor to autonomously detect anomalies. Leveraging real-time operational data from the AGN-201 DT, the IFML algorithm identifies outliers without prior data labeling and operates as a lightweight, complementary approach to traditional physics-based anomaly detection methods for nuclear safeguards. In a simulated Red vs. Blue team exercise, the IFML algorithm successfully detected six significant unseen anomalies related to reactivity changes, achieving an accuracy of 99% for identifying operational deviationxs. These anomalies, caused by deliberate perturbations, were detected alongside known physics-based models, underscoring the potential of IFML to enhance real-time monitoring without displacing traditional methods. Further, this study highlights the applicability of IFML in nuclear environments by providing an additional, redundant layer of anomaly detection to improve safeguards and operational safety in complex systems.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

An anomaly detection framework for dynamic systems using a Bayesian hierarchical framework

Complex systems are susceptible to many types of anomalies, faults, and abnormal behavior caused by a variety of off-nominal conditions that may ultimately result in major failures or catastrophic events. Early and accurate detection of these anomalies using system inputs and outputs collected from sensors and smart devices has become a challenging problem and an active area of research in many application domains. In this article, we present a new Bayesian hierarchical framework that is able to model the relationship between system inputs (sensor measurements) and outputs (response variables) without imposing strong distributional/parametric assumptions while using only a subset of training samples and sensor attributes. Then, an optimal cost-sensitive anomaly detection framework is proposed to determine whether a sample is an anomalous one taking into consideration the trade-off between misclassification errors and detection rates. The model can be used for both supervised and unsupervised settings depending on the availability of data regarding the behavior of the system under anomaly conditions. The unsupervised model is particularly useful when it is prohibitive to identify in advance the anomalies that a system may present and where no data are available regarding the behavior of the system under anomaly conditions. A Bayesian hierarchical setting is used to structure the proposed framework and help with accommodating uncertainty, imposing interpretability, and controlling the sparsity and complexity of the proposed anomaly detection framework. A Markov chain Monte Carlo algorithm is also developed for model training using past data. Furthermore, the numerical experiments conducted using a simulated data set and a wind turbine data set demonstrate the successful application of the proposed work for system response modeling and anomaly detection.

17 WIND ENERGY↗

The F-t-Pj-RG method: An adjacent-rolling-windows based steady-state detection technique for application to kinetic Monte Carlo simulations

A window-based steady-state detection algorithm has been developed for application to kinetic Monte Carlo simulation data. The algorithm, termed F-t-Pj-RG sequentially applies an F-test, a t-test, and a projection test on adjacent windows of the data while rolling (or shifting) and growing the windows when any of the tests fail. In aggregate, the algorithm is able to (a) automatically reject the warm-up period as not being at steady-state, as well as (b) determine an appropriate window size for converged statistics when sampling the data, which is necessary for detection of steady-state, and (c) detect steady-state within a particular tolerance. The last step, the projection test, is actually an oscillating-slope projection test, and is performed on j sequential data windows (i.e., more than two adjacent windows). It requires more than simply being within the user defined tolerance: the oscillating-slope projection test includes a condition that the slope must oscillate around zero when 2, which is an additional indication of steady-state. When all three tests are passed, the F-t-Pj test is passed, indicating that the prerequisites of steady-state detection have been met and also that conditions consistent with the definition of steady-state have been realized. This algorithm is applied to a variety of data sets that correspond to the diverse type of data trends that can be produced by kinetic Monte Carlo simulations. The algorithm is shown to be robust in its ability to handle differing functional forms, and is able to detect steady-state with low computational cost. Finally, the low computational cost of this method and its robustness towards varied data trends make it suitable for on-the-fly use in kinetic Monte Carlo simulations.

97 MATHEMATICS AND COMPUTING↗

Emerging anomaly detection techniques for electronic health records: A survey

Background Anomaly detection in electronic health records (EHRs) is a cornerstone of biomedical informatics, with direct implications for patient safety, clinical decision-making, and the prevention of healthcare fraud. Once guided primarily by simple rule-based methods, the field has advanced rapidly, driven by increased computing power, richer and more detailed health data, and the rise of machine learning and deep learning techniques. The objective of this paper is to provide a comprehensive overview of modern approaches to detecting anomalies in EHRs, outlining their strengths, limitations, and relevance to key healthcare challenges. We review traditional statistical methods alongside newer ML- and DL-based strategies and hybrid models, with particular attention to how these techniques support transparency and build clinical trust. Methods This paper presents a thorough and critical survey through systematic review (PRISMA-based) of the latest anomaly detection strategies in time-sequence data domains within electronic health record systems. Results We explore a broad spectrum of methodologies, including statistical models, supervised and unsupervised learning approaches, hybrid frameworks, and state-of-the-art ML-based techniques that collectively advance the precision and scalability of detecting anomalies in complex clinical datasets. In addition to mapping current capabilities, we address the enduring challenges that hinder widespread implementation and provide a forward-looking perspective on the future of anomaly detection in the data-rich landscape of modern healthcare. Summary The advancement in AI-based approaches is reported along with the basic principles of the individual approaches and their applicability. The increased availability of high-quality data, advancements in DL approaches, and enhanced computation power are leading to more frequent adaptation of DL-based approaches. Emerging DL-based approaches that have been adapted in other domains or recently applied in the EHR domain are also discussed in detail. Although DL-based approaches can improve model predictions by incorporating comorbidities, their application is limited in low-frequency data domains (e.g., when the total available data remains in the single digits). Therefore, the user must carefully consider the application based on data availability.

Anomaly detection↗

Selective fluorescence sensors for detection of nitroaniline and metal Ions based on ligand-based luminescent metal-organic frameworks

Metal-organic frameworks (MOFs) are porous crystalline materials with high potential for applications in fluorescence sensors. In this work, two solvent-induced Zn(II)–based metal-organic frameworks, Zn{sub 3}L{sub 3}(DMF){sub 2} (1) and Zn{sub 3}L{sub 3}(DMA){sub 2}(H{sub 2}O){sub 3} (2) (L=4,4′-stilbenedicarboxylic acid), were investigated as selective sensing materials for detection of nitroaromatic compounds and metal ions. The sensing experiments show that 1 and 2 both exhibit selective fluorescence quenching toward nitroaniline with a low detection limit. In addition, 1 exhibits high selectivity for detection of Fe{sup 3+} and Al{sup 3+} by significant fluorescence quenching or enhancement effect. While for 2, it only exhibits significant fluorescence quenching effect for Fe{sup 3+}. The results indicate that 1 and 2 are both promising fluorescence sensors for detecting and recognizing nitroaniline and metal ions with high sensitivity and selectivity. - Graphical abstract: Two MOFs have been selected as the fluorescence sensing materials for selectively sensing mitroaromatic compounds and metal ions. The high selectivity makes them promising fluorescence sensors for detecting and recognizing nitroaniline and Fe{sup 3+} or Al{sup 3+}.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

A nanoscale Zr-based fluorescent metal-organic framework for selective and sensitive detection of hydrogen sulfide

Hydrogen sulfide (H{sub 2}S) has been commonly viewed as a gas signaling molecule in various physiological and pathological processes. However, the highly efficient H{sub 2}S detection still remains challenging. Herein, we designed a new robust nano metal-organic framework (MOF) UiO-66-CH=CH{sub 2} as a fluorescent probe for rapid, sensitive and selective detection of biological H{sub 2}S. UiO-66-CH=CH{sub 2} was prepared by heating ZrCl{sub 4} and 2-vinylterephthalic acid via a simple method. UiO-66-CH=CH{sub 2} displayed fluorescence quenching to H{sub 2}S and kept excellent selectivity in the presence of biological relevant analytes especially the cysteine and glutathione. This MOF-based probe also exhibited fast response (10 s) and high sensitivity with a detection limit of 6.46 μM which was within the concentration range of biological H{sub 2}S in living system. Moreover, this constructed MOF featured water-stability, nanoscale (20–30 nm) and low toxicity, which made it a promising candidate for biological H{sub 2}S sensing. - Graphical abstract: A nanoscale Zr-based fluorescent metal-organic framework was synthesized for selective and sensitive biological detection of hydrogen sulfide. Display Omitted - Highlights: • We designed a new metal-organic framework UiO-66-CH=CH{sub 2} for biological H{sub 2}S sensing. • The responsive time was 10 s and the detection limit was 6.46 μM. • This probe has anti-interference especially from cysteine and glutathione. • This biological H{sub 2}S probe features low cytotoxicity, water-stability and nanoscale.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Electrochemically decorated gold nanoparticles on CVD graphene ChemFET sensor for the highly sensitive detection of As(III)

Here, in this paper, we report a novel reusable receptor-free chemically sensitive field-effect transistor (ChemFET) sensor for the sensitive detection of As(III) using electrochemical doping of Au nanoparticles (AuNPs)-chemical vapour deposition (CVD) graphene (Gr) sensing film (AuNPs-Gr). The sensor consists of a single-gap gold electrode and a single layer of CVD graphene as a conducting/sensing channel decorated with a thin layer of electrochemically deposited AuNPs to catalyze the electroreduction of As(III) ions onto the sensing channel. A new detection strategy was proposed by measuring the resistance change rate of the AuNPs-Gr sensing channel modified between the source electrode and drain electrode, wherein the resistance change was caused by the electrochemical doping of As(0). The results indicated that the electrochemical doping of As(0) onto the sensing channel led to an increase in resistance through the doping interaction among As(0), AuNPs and graphene, enabling the proposed sensor to have an extraordinary detection performance with a high sensitivity. Moreover, the proposed sensor can be recycled by removing the As(0) deposited on the sensing film with the aid of a simple electrochemical oxidization process. Additionally, the mechanism of the sensing strategy based on the electrochemical n-doping of As(0) into the AuNPs-Gr sensing film was investigated using a top liquid gate electrode. The As(III) concentration detected by the AuNPs-Gr ChemFET sensor was as low as 0.001 μg/L, demonstrating that such sensors with a compatible sensing strategy can be used to detect As(III) with high sensitivity, easy fabrication, fast response and can be recycled.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Sensitivity analysis of high resolution gamma-ray detection for safeguards monitoring at natural uranium conversion facilities

Under the policies proposed by recent International Atomic Energy Agency (IAEA) circulars and policy papers, implementation of safeguards exists when any purified aqueous uranium solution or uranium oxides suitable for isotopic enrichment or fuel fabrication exists. Under IAEA Policy Paper 18, the starting point for nuclear material under safeguards was reinterpreted, suggesting that purified uranium compounds should be subject to safeguards procedures no later than the first point in the conversion process. In response to this technical need, a combination of simulation models and experimental measurements were employed in previous work to develop and validate gamma-ray nondestructive assay monitoring systems in a natural uranium conversion plant (NUCP). In particular, uranyl nitrate (UO 2 (NO 3 ) 2 ) solution exiting solvent extraction was identified as a key measurement point (KMP). Passive nondestructive assay techniques using high resolution gamma-ray spectroscopy were evaluated to determine their viability as a technical means for drawing safeguards conclusions at NUCPs, and if the IAEA detection requirements of 1 significant quantity (SQ) can be met in a timely manner. Building upon the aforementioned previous validation work on detector sensitivity to varying concentrations of uranyl nitrate via a series of dilution measurements, this work investigates detector response parameter sensitivities to gamma-ray signatures of uranyl nitrate. The full energy peak efficiency of a detection system is dependent upon the sample, geometry, absorption, and intrinsic efficiency parameters. Perturbation of these parameters translates into corresponding variations of the 185.7 keV peak area of the 235 U in uranyl nitrate. Such perturbations in the assayed signature impact the quality or versatility of the safeguards conclusions drawn. Given the potentially high throughput of uranyl nitrate in NUCPs, the ability to assay 1 SQ of material requires uncertainty «1%. Accounting for material self-shielding properties, pipe thickness, and source-detector orientation is instrumental in determining the robustness of gamma-ray detection in the process monitoring of uranyl nitrate in NUCPs. Monte Carlo models and ray-tracing models were employed to determine the sensitivity of the detected 185.7 keV photon to self-shielding properties, pipe thickness, and source-detector geometry. Considering the implementation of the detection of 1 SQ, diversion of 1 SQ becomes essentially undetectable given the systematic uncertainty, in addition to considerations such as propagating uncertainties due to pipe offset/position, as well as minor variations in pipe thickness. Consequently, pipe thickness was the most sensitive variable in affecting full energy efficiency of the 185.7 keV signature peak with up to 8% variation in efficiency for ±0.5 mm changes in Schedule 40 304L stainless steel piping. Furthermore, computation of the attenuation correction factor of the uranyl nitrate solution [CF(AT) (i.e. εsample)] using Parker's method using with the approximation for the geometrical factor κ≈π/4 was validated through experimental, Monte Carlo and ray-tracing calculations for a uranyl nitrate filled transfer pipe segment. Furthermore, quantifying sensitivity in detector position, as well as voiding effects due to bubbly flow or laminar flow with an air gap in the uranyl nitrate becomes increasingly important as considerations from (static) design-scale measurements translate into (dynamic) field operations tests.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗