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At least 973 records · Page 54

Increased response to insulin of glucose metabolism in the 6-day unloaded rat soleus muscle

Hind leg muscles of female rats were unloaded by tail cast suspension for 6 days. In the fresh-frozen unloaded soleus, the significantly greater concentration of glycogen correlated with a lower activity ratio of glycogen phosphorylase (p less than 0.02). The activity ratio of glycogen synthase also was lower (p less than 0.001), possibly due to the higher concentration of glycogen. In isolated unloaded soleus, insulin (0.1 milliunit/ml) increased the oxidation of D(U-C-14) glucose, release of lactate and pyruvate, incorporation of D-(U-C-14) glucose into glycogen, and the concentration of glucose 6-phosphate more (p less than 0.05) than in the weight-bearing soleus. At physiological doses of insulin, the percent of maximal uptake of 2-deoxy-D-(1,2-H-3) glucose/muscle also was greater in the unloaded soleus. Unloading of the soleus increased, by 50 percent the concentration of insuling receptors, due to no decrease in total receptor number during muscle atrophy. This increase may account for the greater response of glucose metabolism to insulin in this muscle. The extensor digitorum longus, which generally shows little response to unloading, displayed no differential response of glucose metabolism to insulin.

Henriksen, Erik J.↗

The coronal mass ejection of July 6, 1980 - A candidate for interpretation as a coronal shock wave

The July 6, 1980 looplike coronal mass ejection observed with the Solar Maximum Mission coronagraph is described and analyzed. Two observations are given special consideration: (1) the sides of the loop moved laterally while they were visible and did not form stationary bright columns, or 'legs', in the late stage, and (2) raylike features initially outside the mass ejection loop were not pushed aside or bent until the laterally moving loop sides passed over them. These observations, as well as the results of quantitative analysis of the motion of the bright loop, are consistent with the identification of the bright loop as a shock front. The loop top moved outward faster (at about 1000 km/s) than most mass ejections studied previously, and possibly faster than the Alfven speed in the corona, while the loop sides moved laterally at a speed of about 800 km/s and showed no evidence of deceleration. The excess mass in the bright loop is estimated to be less than about 2 x 10 to the 14th g, well below the value found to be typical of coronal mass ejections.

Sime, D. G.↗

Particle propagation, wave growth and energy dissipation in a flaring flux tube

Wave amplification by downgoing particles in a common flare model is investigated. The flare is assumed to occur at the top of a coronal magnetic flux loop, and results in the heating of plasma in the flaring region. The hot electrons propagate down the legs of the flux tube towards increasing magnetic field. It is simple to demonstrate that the velocity distributions which result in this model are unstable to both beam instabilities and cyclotron maser action. An explanation is presented for the propagation effects on the distribution, and the properties of the resulting amplified waves are explored, concentrating on cyclotron maser action, which has properties (emission in the z mode below the local gyrofrequency) quite different from maser action by other distributions considered in the context of solar flares. The z mode waves will be damped in the coronal plasma surrounding the flaring flux tube and lead to heating there. This process may be important in the overall energy budget of the flare. The downgoing maser is compared with the loss cone maser, which is more likely to produce observable bursts.

White, S. M.↗

Potential benefits of maximal exercise just prior to return from weightlessness

The purpose of this study was to determine whether performance of a single maximal bout of exercise during weightlessness within hours of return to earth would enhance recovery of aerobic fitness and physical work capacities under a 1G environment. Ten healthy men were subjected to a 10-d bedrest period in the 6-deg headdown position. A graded maximal supine cycle ergometer test was performed before and at the end of bedrest to simulate exercise during weightlessness. Following 3 h of resumption of the upright posture, a second maximal exercise test was performed on a treadmill to measure work capacity under conditions of 1G. Compared to before bedrest, peak oxygen consumption, V(O2), decreased by 8.7 percent and peak heart rate (HR) increased by 5.6 percent in the supine cycle test at the end of bedrest. However, there were no significant changes in peak V(O2) and peak HR in the upright treadmill test following bedrest. These data suggest that one bout of maximal leg exercise prior to return from 10 d of weightlessness may be adequate to restore preflight aerobic fitness and physical work capacity.

Convertino, Victor A.↗

Count Bowell at record heliocentric distance

New observations of Comet Bowell at the record distance of 13.6 AU are presented. An extended coma is present, the size of which is consistent with the same slow expansion rate of roughly 1 m/s detected around perihelion. The cross-section of the solid grains within the central 10 arcsec of the coma has decreased by over an order of magnitude since 1980-84, which indicates that the coma production is declining. The decline began near R of roughly 10 AU, the same distance at which production began on the preperihelion leg. The coma at R of 10 AU or less may be formed by sublimation of CO2 or an ice of similar volatility from the nucleus.

Meech, Karen J.↗

On the association of erupting magnetic fields with eruptive prominences and coronal mass ejections

A number of space and ground-based observations give evidence that the eruptive prominences, coronal mass ejections (CMEs) and associated shocks are generated by a common cause, i.e., the eruption of the magnetic field on the Sun. Some 60% of the observed CMEs are associated with the eruptive prominences. It is believed that in reality a much better correlation should be between these events because of observational limitations and of the effect of partial eruption. Some recent results on the formation and evolution of the quiescent and the active region prominences give an idea on the early phase of eruption of the magnetic field with the prominence plasma frozen in. In the latter phase of eruption the magnetic field lifted high into the corona and is seen (as manifested by the cold plasma frozen in) as a system of huge loops - evidently the result of some reconnections at lower heights. The legs of these erupting loops interact sometimes with the local magnetic field, i.e., it often appears to be an active region. In consequence of this interaction the activation of prominences and generation of flares can take place on some occasions as well as ejection of surges and sprays.

Rompolt, Bogdan↗

Loop interaction in the visible emission corona: Morphological details

Coronagraph observations of two post flare loop systems, recorded photographically in the emissions of Fe 14 (5303 A) and Fe 10 (6374 A), show occasional enhancements at the intersections of some loops. The brightness of such enhancements in the green line gradually increases to a maximum value several times greater than that of the legs of the loops and then declines with a typical lifetime approx. 30 to 60 min. In red line emission the loop systems are usually very faint, but show the same overall type of enhancement, with a lag in maximum brightness relative to that of the green line approx. 10 min. The electron density, derived from the cooling time, is approx. 10 to the 12th power/cu cm.

Smartt, Raymond N.↗

P-31 Magnetic Resonance Spectroscopy (MRS) of limb muscles during bedrest with exercise countermeasures

Nineteen volunteers in bed with head down tilt (-6 deg) for 1 month and doing or not exercise training while in bed (lido or ergometer) had their limb muscle studied by magnetic resonance spectroscopy. A protocol of repetitive exercise in the magnet was set and a wooden probe designed to support the limb and to allow exercise. Spectra were recorded continuously during the protocol. In each spectrum, inorganic phosphate, phosphocreatin, adenosin triphosphate, and pH were measured. All the subjects were studied before, after bedrest, and 6 weeks later. After 1 month, the lido group show no changes in the spectra of their leg muscles while the group doing no exercise or ergometer do. For the arms, a loss of muscle function is only seen in the group doing no exercise.

Berry, P.↗

Renal effects of anti-gravity suit inflation in man in relation to cardiovascular and hormonal changes

It is shown that inflation for 3 hr of an antigravity suit that covered the legs and abdomen of normal standing subjects results in significant increases in urine flow, osmolar and free water clearances, total and fractional sodium excretion, and potassium excretion, while glomerular filtration rate and renal plasma flow are transiently increased. Such changes in kidney function are the consequence of the increase in thoracic blood volume induced by inflation which also results in an immediate increase in blood pressure and reflex bradycardia, together with a progressive lowering of plasma renin activity and aldosterone. The changes in kidney excretory patterns brought about by suit inflation appear to be similar in nature and magnitude to those observed during water immersion or in the early phase of bed rest, situations known to result in a headward redistribution of blood.

Geelen, G.↗

Variable response load limiting device

An energy absorbing device used as a load limiting member in a structure to control its response to applied loads is described. It functions by utilizing a spool assembly having flanged ends and an interior cavity of sufficiently large diameter to cause it to deform plastically at a prescribed load. In application, the spool is utilized as a pivot point for the legs of an airplane seat. When properly designed and integrated into the seat arrangement the spool will twist about its axis, deforming plastically when the impact load exceeds the spool yield value. Through this deformation, the spool absorbs the kinetic energy of the movement of the seat at a substantially constant rate, thereby controlling the level of loads transmitted to the seat occupant. By proper sizing and collection of materials, it is possible to control load response in a predictable manner.

Mcsmith, Dwight D.↗

Physiology of prolonged bed rest

Bed rest has been a normal procedure used by physicians for centuries in the treatment of injury and disease. Exposure of patients to prolonged bed rest in the horizontal position induces adaptive deconditioning responses. While deconditioning responses are appropriate for patients or test subjects in the horizontal position, they usually result in adverse physiological responses (fainting, muscular weakness) when the patient assume the upright posture. These deconditioning responses result from reduction in hydrostatic pressure within the cardiovascular system, virtual elimination of longitudinal pressure on the long bones, some decrease in total body metabolism, changes in diet, and perhaps psychological impact from the different environment. Almost every system in the body is affected. An early stimulus is the cephalic shift of fluid from the legs which increases atrial pressure and induces compensatory responses for fluid and electrolyte redistribution. Without countermeasures, deterioration in strength and muscle function occurs within 1 wk while increased calcium loss may continue for months. Research should also focus on drug and carbohydrate metabolism.

Greenleaf, J. E.↗

Physiologic adaptation of man in space; Proceedings of the Seventh International Man in Space Symposium, Houston, TX, Feb. 10-13, 1986

Topics discussed in this volume include space motion sickness, cardiovascular adaptation, fluid shifts, extravehicular activity, general physiology, perception, vestibular response modifications, vestibular physiology, and pharmacology. Papers are presented on the clinical characterization and etiology of space motion sickness, ultrasound techniques in space medicine, fluid shifts in weightlessness, Space Shuttle inflight and postflight fluid shifts measured by leg volume changes, and the probability of oxygen toxicity in an 8-psi space suit. Consideration is also given to the metabolic and hormonal status of crewmembers in short-term space flights, adaptive changes in perception of body orientation and mental image rotation in microgravity, the effects of a visual-vestibular stimulus on the vestibulo-ocular reflex, rotation tests in the weightless phase of parabolic flight, and the mechanisms of antimotion sickness drugs.

Holland, Albert W.↗

Hybrid honeycomb panel heat rejection system

The evolution of a hybrid honeycomb panel heat rejection system concept for future high-power spacecraft is described. Performance evaluation of this heat pipe-based hybrid radiator is based on data and prediction models from a developmental component hardware testing program. The concept integrates three high-performance components into an optimized radiator system. These components are the sideflow heat pipe transport leg, honeycomb panel evaporator, and light-weight high-efficiency heat pipe fins. A 3.05 m (10 ft.) long hybrid radiator was designed considering remnant hardware available from other Hughes programs. The key performance objective for the hybrid radiator was to demonstrate high thermal transport capacity, increased radiating fin lengths, improved thermal efficiency across structural boundaries, and reduced weight. Analysis showed that 9000 W can be transported over a 3.05 m radiator and that finlengths of up to 1 m are possible.

Tanzer, H. J.↗

Outgassing asymmetry of periodic comet Encke. I - Apparitions 1924-1984

A concept of a collimated flow of ejecta from a discrete source (vent) on the surface of a rotating cometary nucleus is applied to P/Encke, based on positional observations of its sunward fanlike coma at 13 apparitions between 1924 and 1984. The major results include a finding that the observations are consistent with an invariable position of the rotation pole during the 60 yr (yielding an obliquity of 70 deg), although this is not to be interpreted as an indication that the nucleus is not precessing. Two vents are identified on the nucleus surface: one on the northern hemisphere at a latitude of +55 deg, of an estimated sublimitation area of 0.4 sq km, which is active along the inbound leg of the comet's orbit until a few days preperihelion and again beginning several weeks postperihelion; the other on the southern hemisphere at -75 deg, of an estimated area of 0.6 sq km, whose activity prevails in the intervening time. There appears to be a significant difference between the two regions in terms of dust content in their emissions.

Sekanina, Z.↗

Stochastic estimation of organized turbulent structure - Homogeneous shear flow

A generalization of the conditional-eddy concept is proposed in which the conditional event specifies the local kinematic state in terms of the velocity and the deformation. Results are presented for stochastically estimated conditional eddies given the local kinematics. The equation governing the probability density function of a kinematic state has been derived for constant-property incompressible flow, providing a link between coherent flow structures corresponding to the conditional eddies and the modelling of turbulent transport. The primary contributions to the second-quadrant and fourth-quadrant Reynolds-stress events in homogeneous shear flow are shown to come from flow induced through the 'legs' and close to the 'heads' of upright and inverted 'hairpins', respectively.

Adrian, Ronald J.↗

Measurements of natural circulation flow in a scale model PWR reactor system during postulated degraded core accidents using laser anemometry

The natural circulation of a single-phase fluid in a scale-model pressurized water reactor system was studied during a postulated degraded core accident. A half section of a one-seventh scale model with a plexiglass adiabatic window was employed. Water and SF6 were used as the fluid. LDA was used to perform velocity measurements along the center plane of the model at five elevations. It was found that the recirculation flow patterns are nearly symmetric except near the hot legs and in the upper head and that the fluid in the upper plenum is well mixed.

Kadambi, J. R.↗

Airborne Doppler lidar wind field measurements of waves in the lee of Mount Shasta

Doppler lidar wind data obtained along one leg of a race track traverse around Mount Shasta are presently studied to establish their value and limitations for the study of orographic flows, as well as to evaluate the relative usefulness of a linear model in the analyses of the observed fields-of-motion. The model successfully reproduced the observed downstream lee of positive horizontal divergence which embedded spatially irregular waves, but the amplitudes of the model downstream divergence is smaller than the observations by a factor of two.

Blumen, William↗

Galileo Earth-Venus trajectory correction maneuver design

As a result of delays in the Space Shuttle program and a re-evaluation of safety concerns which resulted in cancellation of the Shuttle Centaur Upper Stage program, the Galileo mission to Jupiter has undergone a substantial redesign effort. Use of the Inertial Upper Stage (IUS) for injection has necessitated a complicated Venus-Earth-Earth gravity assist trajectory in order to reach Jupiter. One flyby of Venus and two flybys of Earth are required to compensate for the lower injection energy available from the IUS. As the spacecraft was not originally designed for the environment within 1 AU of the Sun, modifications to the spacecraft and operating procedures have been developed. This paper describes some of these changes and how they have affected the design and implementation of trajectory correction maneuvers on the Earth-Venus leg of the mission. A strategy of biasing the IUS target at injection to control the statistical velocity distribution of a subsequent trajectory correction maneuver is discussed.

Wilson, M. G.↗