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DOE OSTI2026

Acute wood smoke exposure is associated with cell-specific hippocampal transcriptomic responses in an accelerated ovarian failure mouse model

Background Wildfire events are increasing in frequency and intensity, and aging individuals demonstrate heightened biological susceptibility to air pollution exposures including increased risk of neurological sequelae. Declining ovarian hormones levels that occur with aging in females along with associated systemic physiological and inflammatory changes may contribute to increased cerebral vulnerability to air pollution, representing a potential but underexplored mechanism. Menopause and the menopausal transition represent a period of profound physiological change that affects cardiovascular, neurological, and immune health. Methods We tested whether peri-menopausal–like hormonal status amplifies hippocampal responses to acute wood smoke (WS) using an ovary-intact, 4-vinylcyclohexene diepoxide (VCD) model of moderate accelerated ovarian failure (AOF) in female C57BL/6 mice. Animals were exposed to HEPA-filtered air (FA) or WS for 4 h/day over 2 consecutive days (∼0.5 mg/m³). Exposure characterization confirmed a complex mixture of combustion products with significant levels of both trace metals and gas release during WS exposure. Results Spatial transcriptomics (10x Visium; n = 4 sections/group) with automated cell-type annotation identified astrocytes, GABAergic and glutamatergic neurons, oligodendrocytes, revealed cell type-specific transcriptional alterations following WS exposure. Distinct transcriptional patterns were observed across all identified neuronal and glial cell populations. Conclusion Together, these findings define a cell-type specific transcriptomic framework describing how WS exposure and ovarian hormone decline interact to influence hippocampal responses and identify potential cellular pathways relevant to hippocampal vulnerability.

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTAN↗

NASA NTRS1987

Profile modification to minimize spur gear dynamic loading

An analytical computer simulation program for dynamic modeling of low-contact-ratio spur gear systems is presented. The procedure computes the static transmission error of the gears operating under load and uses a fast Fourier transform to generate the frequency spectrum of the static transmission error at various tooth profile modifications. The dynamic loading response of an unmodified (perfect involute) gear pair was compared with that of gears with various profile modifications. Correlations were found between various profile modifications and the resulting dynamic loads. An effective error, obtained from frequency domain analysis of the static transmission error of the gears, gave a very good indication of the optimum profile modification to reduce gear dynamic loading. Design curves generated by dynamic simulation at various profile modifications are given for gear systems operated at various loads. Optimum profile modifications can be determined from these design curves for improved gear design.

Lin, Hsiang Hsi↗

NASA NTRS1989

Profile modification to minimize spur gear dynamic loading

Lin, H. H.↗

DOE OSTI2021

Effect of sample anisotropy on scanning near-field optical microscope images

Scattering-type scanning near-field optical microscopy (s-SNOM) has been widely used to characterize strongly correlated electronic, two dimensional, and plasmonic materials, and it has enormous potential for biological applications. Many of these materials exhibit anisotropic responses that complicate the extraction of dielectric constants from s-SNOM measurements. Here, we generalize our recently developed approach for retrieving the near-field scattering signal from isotropic systems and apply it to anisotropic dielectrics. Specifically, we compare our theoretical results with experimental measurements on modestly anisotropic sapphire that exhibit strong resonances at the infrared frequency range. Good agreement with the experimental result is found. Finally, our result is important for understanding the near-field response of low damping, anisotropic polaritonic states in dielectric media.

36 MATERIALS SCIENCE↗

DOE OSTI2020

Superconducting metamaterials - the first step toward a microwave quantum bus

Coherent manipulation of quantum states is at the core of quantum information science (QIS). Many state-of-the-art quantum systems rely on microwave fields for quantum operations. As such, the microwave electromagnetic fields serve as the ideal "quantum bus" to integrate different types of QIS systems into a hybrid quantum system. Superconducting metamaterials are artificial materials consisting of arrays of superconducting resonant microstructures with sizes much smaller than the microwave wavelengths of interest. Superconducting metamaterials are a strong candidate medium for the microwave quantum bus, because the effective impedance, field distributions, and frequency response can all be controlled by engineering the microstructures, electrical bias, and magnetic flux while maintaining extremely low loss. In this project, we investigate the fundamental unit of a superconducting metamaterial - a resonator with physical dimensions much smaller than the microwave wavelengths - using NbTiN as the working superconductor, whose high operating temperatures and magnetic fields are desirable attributes for compatibility with a wide variety of quantum systems. We first studied the properties of sputtered NbTiN thin films by correlating the film thickness with the normal state resistivity, superconducting transition temperature, and resonances of transmission line resonators made from these films. We developed a process flow and designed a coplanar waveguide platform for studying small resonators. The platform significantly shortens the turnaround times of the resonator fabrication and testing cycles. Several resonators with different designs were fabricated and tested at 4 Kelvin. Resonances were observed in some resonator testers. Potential paths for improvements and future directions are discussed.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

NASA NTRS1993

Results from the Middeck 0-gravity Dynamics Experiment

The experimental results of the Middick Zero-gravity Dynamics Experiment (MODE) are presented. MODE investigated the dynamics of two key spacecraft components; contained fluids and jointed truss structures. The change in the lateral slosh behavior of contained fluids and the changes in the modal parameters of space structural test articles from one- to zero-gravity were studied. The experimental apparatus used to determine the dynamic characteristics is described. For the MODE fluid experiments, the forced response characteristics of silicone oil and distilled water in cylinder tanks with either a flat or spherical bottom are reported and discussed. A comparison of the measured earth and space results identifies and highlights the effects of gravity on the linear and nonlinear slosh behavior of these fluids. For the MODE structural experiments, an analytic and experimental study is presented. Deployable, erectable, and rotary modules were assembled to form three one- and two-dimensional structures in which variations in bracing wire and rotary joint preload could be introduced. Analysis is compared with ground experimental measurements made on a spring/wire suspension system with a nominal plunge frequency of one Hertz, and with measurements made on the Shuttle middeck. The degree of change in linear modal parameters as well as the change in nonlinear nature of the response is examined. Trends in modal parameters are presented as a function of force amplitude, joint preload, and ambient gravity level.

Van Schoor, M. C.↗

NASA NTRS2007

NASA Tech Briefs, September 2007

Topics covered include; Rapid Fabrication of Carbide Matrix/Carbon Fiber Composites; Coating Thermoelectric Devices To Suppress Sublimation; Ultrahigh-Temperature Ceramics; Improved C/SiC Ceramic Composites Made Using PIP; Coating Carbon Fibers With Platinum; Two-Band, Low-Loss Microwave Window; MCM Polarimetric Radiometers for Planar Arrays; Aperture-Coupled Thin-Membrane L-Band Antenna; WGM-Based Photonic Local Oscillators and Modulators; Focal-Plane Arrays of Quantum-Dot Infrared Photodetectors; Laser Range and Bearing Finder With No Moving Parts; Microrectenna: A Terahertz Antenna and Rectifier on a Chip; Miniature L-Band Radar Transceiver; Robotic Vision-Based Localization in an Urban Environment; Programs for Testing an SSME-Monitoring System; Cathodoluminescent Source of Intense White Light; Displaying and Analyzing Antenna Radiation Patterns; Payload Operations Support Team Tools; Space-Shuttle Emulator Software; Soft Real-Time PID Control on a VME Computer; Analyzing Radio-Frequency Coverage for the ISS; Nanorod-Based Fast-Response Pressure-Sensitive Paints; Capacitors Would Help Protect Against Hypervelocity Impacts; Diaphragm Pump With Resonant Piezoelectric Drive; Improved Quick-Release Pin Mechanism; Designing Rolling-Element Bearings; Reverse-Tangent Injection in a Centrifugal Compressor; Inertial Measurements for Aero-assisted Navigation (IMAN); Analysis of Complex Valve and Feed Systems; Improved Path Planning Onboard the Mars Exploration Rovers; Robust, Flexible Motion Control for the Mars Explorer Rovers; Solar Sail Spaceflight Simulation; Fluorine-Based DRIE of Fused Silica; Mechanical Alloying for Making Thermoelectric Compounds; Process for High-Rate Fabrication of Alumina Nanotemplates; Electroform/Plasma-Spray Laminates for X-Ray Optics; An Automated Flying-Insect Detection System; Calligraphic Poling of Ferroelectric Material; Blackbody Cavity for Calibrations at 200 to 273 K; KML Super Overlay to WMS Translator; High-Performance Tiled WMS and KML Web Server; Modeling of Radiative Transfer in Protostellar Disks; Composite Pulse Tube; Photometric Calibration of Consumer Video Cameras; Criterion for Identifying Vortices in High- Pressure Flows; Amplified Thermionic Cooling Using Arrays of Nanowires; Delamination-Indicating Thermal Barrier Coatings; Preventing Raman Lasing in High-Q WGM Resonators; Procedures for Tuning a Multiresonator Photonic Filter; Robust Mapping of Incoherent Fiber-Optic Bundles; Extended-Range Ultrarefractive 1D Photonic Crystal Prisms; Rapid Analysis of Mass Distribution of Radiation Shielding; Modeling Magnetic Properties in EZTB; Deep Space Network Antenna Logic Controller; Modeling Carbon and Hydrocarbon Molecular Structures in EZTB; BigView Image Viewing on Tiled Displays; and Imaging Sensor Flight and Test Equipment Software.

Source record↗

NASA NTRS1978

Dynamic response and input identification of MDOF structures subjected to coupled random vector inputs

A method of random dynamic analysis is presented which is based on the classical approach applied to a discretized structure. The method assumes that the system identification is available in the form of natural modes and frequencies. These modes and frequencies can be found from either available solutions or approximately from finite element programs. A computer program has been developed to perform the computations required in the analysis. All computations are performed with transformed modal variables, which results in significant economy since the number of modal degrees of freedom is almost always less than the number of physical degrees of freedom. The program computes the response to force and base inputs which are statistically coupled. A method is also presented for predicting one of the inputs if the second input and the acceleration response at a point on the structure are known. Finally, results are presented for the random response of a rectangular plate subjected to a random pressure and a random base input. The inputs are considered individually and with various degrees of statistical coupling.

Ocallahan, J. C.↗

NASA NTRS1972

Characteristics of hingeless rotors with hub moment feedback controls including experimental rotor frequency response, Volume 1

Wind tunnel tests to determine the dynamic characteristics of hingeless rotors with hub moment feedback controls and to acquire experimental hingeless rotor transfer functions are discussed. Rotor transfer functions were calculated from data acquired during open loop frequency response tests. The transfer functions are linear and present the rotor longitudinal and lateral frequency responses to collective pitch, longitudinal cyclic pitch, and lateral cyclic pitch. The theoretical analysis was based on the rigid blade flapping model coupled with appropriate control system and cyclic pitch actuator equations of motion.

Kuczynski, W. A.↗

NASA NTRS1973

Dynamics of Flexible Spinning Satellites with Radial Wire Antennas

A dynamic analysis is presented for a spin stabilized spacecraft employing four radial wire antennas with tip masses, a configuration first employed in the IMP-J spacecraft. The use of wires in place of the usual booms represents the ultimate in weight reduction at the expanse of flexibility. The satellite is modelled as a 14 degree of freedom system, and the linearized equations of motion are found. The lowest order vibrational modes and natural frequencies of the gyroscopically coupled system are then determined. Because the satellite spin rate is decreased by antenna deployment, a spin-up maneuver is needed. The response of the time varying mode equations during spin-up is found, for the planar modes, in terms of Bessel functions and a Struve function of order -1/4. Because tables of the latter are not readily available, the particular solution is expressed in various forms including an infinite series of Bessel functions and a particularly useful asymptotic expansion.

Longman, R. W.↗

NASA NTRS1976

Dynamics of flexible spinning satellites with radial wire antennas

A dynamic analysis is presented for a spin-stabilized spacecraft employing four radial wire antennas with tip masses. The satellite is modelled as a 14-degree-of-freedom system, and the linearized equations of motion are found. The lowest-order vibrational modes and natural frequencies of the gyroscopically coupled system are then determined. Because the satellite spin rate is decreased by antenna deployment, a spin-up maneuver is needed. The response of the time-varying mode equations during spin-up is found for the planar modes in terms of Bessel functions and a Struve function of order -0.25. The particular solution is expressed in various forms, including an infinite series of Bessel functions and a particularly useful asymptotic expansion. An error formula for the latter is derived, showing that it gives good accuracy. A simple approximation to the complementary function is obtained using the Wenzel-Kramers-Brillouin method, and the phase error in the approximation is shown to be small.

Longman, R. W.↗

NASA NTRS1977

Effect of digitally computed drives on performance of continuous linear systems

The dependence of the Bode response upon digital sample rate for first and second order linear continuous systems driven by a digital computer is derived. Open loop lead compensation introduced within the digital computer in order to increase the system bandwidth is also examined in terms of derived Bode responses. This introduction of lead terms within the digital computer is shown to be effective at operating frequencies below the Nyquist frequency. In most practical applications, empirical determination of these lead coefficients appears to be a sufficient compensation method.

Parrish, R. V.↗

NASA NTRS1983

Dynamic-pressure measurements using an electronically scanned pressure module

Frequency response was measured for different lengths and diameters of tubing between a sinusoidal pressure source and a pressure sensing module from an electronically scanned pressure measuring system. Measurements were made for straight runs of both steel and vinyl tubing. For steel tubing, measured results are compared with results calculated by using equations developed by Tijdeman and Bergh. Measurements were also made with a bend in the vinyl tubing at the module. In addition, measurements were made with two coils placed in the tubing near the middle of the run.

Chapin, W. G.↗

NASA NTRS1989

Modal coupling and acoustic intensity measurements

Acoustic-intensity measurement techniques for highly resonant coupled structural-acoustic systems are discussed. Frequency-averaging effects are shown to cause inaccurate results in such systems, and it is recommended that the analysis bandwidth be selected carefully to account for the response modal density and Q factor. The applicability of these findings to the analysis of reverberation chambers is indicated.

Silcox, R. J.↗

NASA NTRS1992

Rigid body mode identification of the PAH-2 helicopter using the eigensystem realization algorithm

The rigid body modes of the PAH-2 'Tiger' helicopter were identified using the Eigensystem Realization Algorithm (ERA). This work complements ground vibration tests performed using DLR's traditional phase resonance technique and the ISSPA (Identification of Structural System Parameters) method. Rigid body modal parameters are important for ground resonance prediction. Time-domain data for ERA were obtained by inverse Fourier transformation of frequency response functions measured with stepped-sine excitation. Mode purity (based on the Phase Resonance Criterion) was generally equal to or greater than corresponding results obtained in the ground vibration tests. All identified natural frequencies and mode shapes correlate well with corresponding ground vibration test results. The modal identification approach discussed in this report has become increasingly attractive in recent years due to the steadily declining cost and increased performance of scientific computers. As illustrated in this application, modern time-domain methods can be successfully applied to data acquired using DLR's existing test equipment. Some suggestions are made for future applications of time domain modal identification in this manner.

Schenk, Axel↗

NASA NTRS1993

Advanced communications technology satellite high burst rate link evaluation terminal communication protocol software user's guide, version 1.0

The Communication Protocol Software was developed at the NASA Lewis Research Center to support the Advanced Communications Technology Satellite High Burst Rate Link Evaluation Terminal (ACTS HBR-LET). The HBR-LET is an experimenters terminal to communicate with the ACTS for various experiments by government, university, and industry agencies. The Communication Protocol Software is one segment of the Control and Performance Monitor (C&PM) Software system of the HBR-LET. The Communication Protocol Software allows users to control and configure the Intermediate Frequency Switch Matrix (IFSM) on board the ACTS to yield a desired path through the spacecraft payload. Besides IFSM control, the C&PM Software System is also responsible for instrument control during HBR-LET experiments, uplink power control of the HBR-LET to demonstrate power augmentation during signal fade events, and data display. The Communication Protocol Software User's Guide, Version 1.0 (NASA CR-189162) outlines the commands and procedures to install and operate the Communication Protocol Software. Configuration files used to control the IFSM, operator commands, and error recovery procedures are discussed. The Communication Protocol Software Maintenance Manual, Version 1.0 (NASA CR-189163, to be published) is a programmer's guide to the Communication Protocol Software. This manual details the current implementation of the software from a technical perspective. Included is an overview of the Communication Protocol Software, computer algorithms, format representations, and computer hardware configuration. The Communication Protocol Software Test Plan (NASA CR-189164, to be published) provides a step-by-step procedure to verify the operation of the software. Included in the Test Plan is command transmission, telemetry reception, error detection, and error recovery procedures.

Reinhart, Richard C.↗

NASA NTRS1995

Test results of a 20 GHz, low noise downconverter for USAT applications

A key component in the development of the Advanced Communications Technology Satellite (ACTS) ultra small aperture terminal (USAT) earth station is the low noise downconverter (NLD). NASA Lewis Research Center (LeRC) has tested a version of an LND designed by Electrodyne Systems Corporation. A number of tests were conducted to characterize the radio frequency performance of the LND over temperature. The test results presented in this paper are frequency response, noise figure, gain, group delay, power transfer characteristics, image rejection, and spurious product suppression. The LND was one of several critical microwave subsystems developed and tested for the ACTS USAT earth stations.

Fujikawa, Gene↗

NASA NTRS1993

Evaluation of simulation motion fidelity criteria in the vertical and directional axes

An evaluation of existing motion fidelity criteria was conducted on the NASA Ames Vertical Motion Simulator. Experienced test pilots flew single-axis repositioning tasks in both the vertical and the directional axes. Using a first-order approximation of a hovering helicopter, tasks were flown with variations only in the filters that attenuate the commands to the simulator motion system. These filters had second-order high-pass characteristics, and the variations were made in the filter gain and natural frequency. The variations spanned motion response characteristics from nearly full math-model motion to fixed-base. Between configurations, pilots recalibrated their motion response perception by flying the task with full motion. Pilots subjectively rated the motion fidelity of subsequent configurations relative to this full motion case, which was considered the standard for comparison. The results suggested that the existing vertical-axis criterion was accurate for combinations of gain and natural frequency changes. However, if only the gain or the natural frequency was changed, the rated motion fidelity was better than the criterion predicted. In the vertical axis, the objective and subjective results indicated that a larger gain reduction was tolerated than the existing criterion allowed. The limited data collected in the yaw axis revealed that pilots had difficulty in distinguishing among the variations in the pure yaw motion cues.

Schroeder, Jeffery A.↗