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At least 955 records · Page 53

SU-E-J-252: Reproducibility of Radiogenomic Image Features: Comparison of Two Semi-Automated Segmentation Methods

Purpose: Objective and reliable quantification of imaging phenotype is an essential part of radiogenomic studies. We compared the reproducibility of two semi-automatic segmentation methods for quantitative image phenotyping in magnetic resonance imaging (MRI) of glioblastoma multiforme (GBM). Methods: MRI examinations with T1 post-gadolinium and FLAIR sequences of 10 GBM patients were downloaded from the Cancer Image Archive site. Two semi-automatic segmentation tools with different algorithms (deformable model and grow cut method) were used to segment contrast enhancement, necrosis and edema regions by two independent observers. A total of 21 imaging features consisting of area and edge groups were extracted automatically from the segmented tumor. The inter-observer variability and coefficient of variation (COV) were calculated to evaluate the reproducibility. Results: Inter-observer correlations and coefficient of variation of imaging features with the deformable model ranged from 0.953 to 0.999 and 2.1% to 9.2%, respectively, and the grow cut method ranged from 0.799 to 0.976 and 3.5% to 26.6%, respectively. Coefficient of variation for especially important features which were previously reported as predictive of patient survival were: 3.4% with deformable model and 7.4% with grow cut method for the proportion of contrast enhanced tumor region; 5.5% with deformable model and 25.7% with grow cut method for the proportion of necrosis; and 2.1% with deformable model and 4.4% with grow cut method for edge sharpness of tumor on CE-T1W1. Conclusion: Comparison of two semi-automated tumor segmentation techniques shows reliable image feature extraction for radiogenomic analysis of GBM patients with multiparametric Brain MRI.

60 APPLIED LIFE SCIENCES↗

Land use classification using texture information in ERTS-A MSS imagery

The author has identified the following significant results. Preliminary digital analysis of ERTS-1 MSS imagery reveals that the textural features of the imagery are very useful for land use classification. A procedure for extracting the textural features of ERTS-1 imagery is presented and the results of a land use classification scheme based on the textural features are also presented. The land use classification algorithm using textural features was tested on a 5100 square mile area covered by part of an ERTS-1 MSS band 5 image over the California coastline. The image covering this area was blocked into 648 subimages of size 8.9 square miles each. Based on a color composite of the image set, a total of 7 land use categories were identified. These land use categories are: coastal forest, woodlands, annual grasslands, urban areas, large irrigated fields, small irrigated fields, and water. The automatic classifier was trained to identify the land use categories using only the textural characteristics of the subimages; 75 percent of the subimages were assigned correct identifications. Since texture and spectral features provide completely different kinds of information, a significant increase in identification accuracy will take place when both features are used together.

Haralick, R. M.↗

Spatial variation analyses of Thematic Mapper data for the identification of linear features in agricultural landscapes

A need exists for digitized information pertaining to linear features such as roads, streams, water bodies and agricultural field boundaries as component parts of a data base. For many areas where this data may not yet exist or is in need of updating, these features may be extracted from remotely sensed digital data. This paper examines two approaches for identifying linear features, one utilizing raw data and the other classified data. Each approach uses a series of data enhancement procedures including derivation of standard deviation values, principal component analysis and filtering procedures using a high-pass window matrix. Just as certain bands better classify different land covers, so too do these bands exhibit high spectral contrast by which boundaries between land covers can be delineated. A few applications for this kind of data are briefly discussed, including its potential in a Universal Soil Loss Equation Model.

Pelletier, R. E.↗

Chain trajectories, domain shapes, and terminal boundaries in block copolymers

The packing geometry of macromolecules in complex mesophases is of key importance to self-organization in synthetic and biological soft materials. While approximate or heuristic models rely on often-untested assumptions about how flexible molecules “fit in” to distinct locations of complex assemblies, physical assemblies derive from ensembles of fluctuating conformations, obscuring the connection between mesophase geometry and the underlying arrangements. Here, we present an approach to extract and analyze features of molecular packing in diblock block copolymer (BCP) melts, a prototypical soft matter system, based on the statistical description of chain conformations in self-consistent field (SCF) theory. We show how average BCP chain trajectories in ordered morphologies can be analyzed from the SCF-derived orientational order parameter of chain segments. We use these extracted trajectories to analyze the features of local packing geometry, including chain bending and tilt, as well as the terminal boundaries that delineate distinct domains in ordered BCP morphologies. In conclusion, we illustrate this analysis by focusing on measurable features of packing frustration in 2D (columnar) and 3D (spherical and bicontinuous) morphologies, notably establishing an explicit link between chain conformations in complex morphologies and their medial geometry.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Investigation of near-field jet stability of a single-hole injector based on fast X-ray phase contrast imaging and image feature matching

Fuel spray is very effective in controlling the combustion process to improve engine performance and reduce emissions. Understanding the spray unstability during the injection process is of importance to improve the control of spray characteristics and engine operation. In this study, near-field biodiesel jets were recorded using fast X-ray phase contrast imaging and the flow features inside the jet were extracted using Speeded Up Robust Features (SURF) method. Here, the image similarity by feature matching was successfully used to represent the near-field jet stability. Based on the jet stability, an injection process can be divided into five stages: an unstable stage at needle opening, a partially stable transition stage at needle opening, a stable stage, a stable transition stage at needle closing and an unstable stage at needle closing. The ranges of needle lift for five stages were also determined. The jet unstability is highly related to the cavitation formation and gas purging process during needle opening. The variation of stable jet feature is dependent on the needle lift at needle closing. Higher needle lift for the similar jet feature at needle opening indicates a hydraulic delay compared to needle closing. Finally, the possible reasons of jet feature formation and feature detection used on the multi-hole injector are discussed.

33 ADVANCED PROPULSION SYSTEMS↗

Data Driven Fault Detection of Premixer Centerbody Degradation in a Swirl Combustor

This paper introduces a data-driven framework for combustor-focused, performance-based condition monitoring of gas turbines. Commercial condition monitoring systems typically generate huge amounts of data that make efficient onboard monitoring challenging. This paper focuses on quantifying combustor component degradation, using premixer centerbody degradation in a swirl stabilized combustor as a case study. The input for these analyses is acoustic pressure measurements acquired at various locations on the combustor. The diagnosis methodology is based on a classification framework and consists of 3 steps: 1) Data curation, 2) Feature Engineering, and 3) Diagnosis. Data curation ensures good quality of the data that is passed through the algorithm. Feature engineering deals with the extraction of the most informative features, from the most informative sensors, that can accurately capture the introduced fault. To perform diagnosis, the classification model is trained using experimentally acquired data and is then tested on a separate data set. The framework was able to achieve high classification accuracy (>99%) for training size as low as 30% of the total recorded observations. The low number of features required to achieve this accuracy suggests high potential for integration into existing onboard condition monitoring systems.

data driven methods, fault detection, swirl flames↗

Determination of latent dimensionality in international trade flow

Currently, high-dimensional data is ubiquitous in data science, which necessitates the development of techniques to decompose and interpret such multidimensional (aka tensor) datasets. Finding a low dimensional representation of the data, that is, its inherent structure, is one of the approaches that can serve to understand the dynamics of low dimensional latent features hidden in the data. Moreover, decomposition methods with non-negative constraints are shown to extract more insightful factors. Nonnegative RESCAL is one such technique, particularly well suited to analyze self-relational data, such as dynamic networks found in international trade flows. Particularly, non-negative RESCAL computes a low dimensional tensor representation by finding the latent space containing multiple modalities. Furthermore, estimating the dimensionality of this latent space is crucial for extracting meaningful latent features. Here, to determine the dimensionality of the latent space with non-negative RESCAL, we propose a latent dimension determination method which is based on clustering of the solutions of multiple realizations of non-negative RESCAL decompositions. We demonstrate the performance of our model selection method on synthetic data. We then apply our method to decompose a network of international trade flows data from International Monetary Fund and shows that with a correct latent dimension determination, the resulting features are able to capture relevant empirical facts from economic literature.

97 MATHEMATICS AND COMPUTING↗

Characterization of Pulmonary Nodules Based on Features of Margin Sharpness and Texture

Lung cancer is the leading cause of cancer-related deaths in the world, and one of its manifestations occurs with the appearance of pulmonary nodules. The classification of pulmonary nodules may be a complex task to specialists due to temporal, subjective, and qualitative aspects. Therefore, it is important to integrate computational tools to the early pulmonary nodule classification process, since they have the potential to characterize objectively and quantitatively the lesions. In this context, the goal of this work is to perform the classification of pulmonary nodules based on image features of texture and margin sharpness. Computed tomography scans were obtained from a publicly available image database. Texture attributes were extracted from a co-occurrence matrix obtained from the nodule volume. Margin sharpness attributes were extracted from perpendicular lines drawn over the borders on all nodule slices. Feature selection was performed by different algorithms. Classification was performed by several machine learning classifiers and assessed by the area under the receiver operating characteristic curve, sensitivity, specificity, and accuracy. Highest classification performance was obtained by a random forest algorithm with all 48 extracted features. However, a decision tree using only two selected features obtained statistically equivalent performance on sensitivity and specificity.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Detection of Synchrophasor False Data Injection Attack using Feature Interactive Network

The synchrophasor data recorded by Phasor Measurement Units (PMUs) plays an increasingly critical role in the regulation and situational awareness of power systems. However, the widely installed PMUs are vulnerable to multiple malicious attacks from cyber hackers during data transmission and storage. To address this problem, a Modified Ensemble Empirical Mode Decomposition (MEEMD) is proposed first to extract the intrinsic mode functions of each Synchrophasor Data Attacks (SDA). The frequency-based adaptive screening criterion embedded in MEEMD is used to eliminate the false intrinsic mode functions. Next, a Multivariate Convolutional Neural Network (MCNN) is proposed to identify multiple SDA by utilizing the extracted intrinsic mode functions and original SDA as input vectors. A fusion block as the main structure of MCNN is also leveraged to increase the diversity of features and compress the model parameters. Integrating MEEMD and MCNN, a framework with automatic feature extraction and multi-source information fusion capability, referred to as Feature Interactive Network (FIN), is proposed to detect multiple SDA. Based on the proposed FIN framework, six types of SDA are explored for the first time using actual synchrophasor data in FNET/Grideye that was collected from different locations in the U.S. Eastern Interconnection. Finally, a large quantity of experiments with different attack strengths are used to evaluate the adaptability and classification performance of the proposed FIN.

24 POWER TRANSMISSION AND DISTRIBUTION↗

SU-F-R-22: Malignancy Classification for Small Pulmonary Nodules with Radiomics and Logistic Regression

Purpose: We conducted a retrospective study of Radiomics research for classifying malignancy of small pulmonary nodules. A machine learning algorithm of logistic regression and open research platform of Radiomics, IBEX (Imaging Biomarker Explorer), were used to evaluate the classification accuracy. Methods: The training set included 100 CT image series from cancer patients with small pulmonary nodules where the average diameter is 1.10 cm. These patients registered at Chang Gung Memorial Hospital and received a CT-guided operation of lung cancer lobectomy. The specimens were classified by experienced pathologists with a B (benign) or M (malignant). CT images with slice thickness of 0.625 mm were acquired from a GE BrightSpeed 16 scanner. The study was formally approved by our institutional internal review board. Nodules were delineated and 374 feature parameters were extracted from IBEX. We first used the t-test and p-value criteria to study which feature can differentiate between group B and M. Then we implemented a logistic regression algorithm to perform nodule malignancy classification. 10-fold cross-validation and the receiver operating characteristic curve (ROC) were used to evaluate the classification accuracy. Finally hierarchical clustering analysis, Spearman rank correlation coefficient, and clustering heat map were used to further study correlation characteristics among different features. Results: 238 features were found differentiable between group B and M based on whether their statistical p-values were less than 0.05. A forward search algorithm was used to select an optimal combination of features for the best classification and 9 features were identified. Our study found the best accuracy of classifying malignancy was 0.79±0.01 with the 10-fold cross-validation. The area under the ROC curve was 0.81±0.02. Conclusion: Benign nodules may be treated as a malignant tumor in low-dose CT and patients may undergo unnecessary surgeries or treatments. Our study may help radiologists to differentiate nodule malignancy for low-dose CT.

60 APPLIED LIFE SCIENCES↗

Comparison of the Mineralogy of Comet Wild 2 Coma Grains to Other Astromaterials

We propose that Kuiper Belt samples (in this case comet coma grains from the Jupiter family comet Wild 2) are recognizably different from the bulk of materials in outer belt asteroids, because of their different formation positions and times in the early solar system. We believe this despite similarities found between some Wild 2 grains and components of carbonaceous chondrites (i.e. some CAI and chondrules). Kuiper Belt samples must preserve measurable mineralogical and compositional evidence of formation at unique positions and times in the early solar nebula, and these formational differences must have imparted recognizable special characteristics. We hypothesize that these characteristics include: (1) Unique major element compositional ranges of common astromaterial minerals, especially olivine and pyroxene; (2) Unique minor element compositions of major silicate phases, especially olivine and low-Ca pyroxene; (3) Degree and effects of radiation processing -- including amorphous rims, metal coatings, and Glass with Embedded Metal and Sulfides (GEMS); (4) Presence of abundant presolar silicate grains as recognized by anomalous oxygen in silicates; (5) Oxidation state of the mineral assemblage. We are working our way through all available Wild 2 samples, selecting 1-2 non-consecutive viable TEM grids from each possible extracted Wild 2 grain. We especially prefer TEM grids from grains for which complete mineralogical details have not been published (which is to say the majority of the extracted grains). We are performing a basic mineralogic survey by E-beam techniques, to establish the essential features of the extracted Wild 2 grains. We are making a particular effort to carefully and accurately measure minor elements of olivine and pyroxene, as these minerals are widespread in astromaterials, and comparisons of their compositions will serve to place the Wild 2 silicates in contact with asteroids, meteorites and chondritic interplanetary dust particles processing. We are also making a special effort to search for mineralogical products of aqueous alteration, since their presence would reveal that Wild 2 was once internally heated, a result with dramatic implications for models of early solar system primitive bodies. Thus far carbonates are the only potential evidence for aqueous alteration for Wild 2.

Frank, David↗

Mixed monofunctional extractants for trivalent actinide/lanthanide separations: TALSPEAK-MME

The basic features of an f-element extraction process based on a solvent composed of equimolar mixtures of Cyanex-923 (a mixed trialkyl phosphine oxide) and 2-ethylhexylphosphonic acid mono-2-ethylhexyl ester (HEH[EHP]) extractants in n-dodecane are investigated in this report. This system, which combines features of the TRPO and TALSPEAK processes, is based on co-extraction of trivalent lanthanides and actinides from 0.1 to 1.0 M HNO 3 followed by application of a buffered aminopolycarboxylate solution strip to accomplish a Reverse TALSPEAK selective removal of actinides. This mixed-extractant medium could enable a simplified approach to selective trivalent f-element extraction and actinide partitioning in a single process. As compared with other combined process applications in development for more compact actinide partitioning processes (DIAMEX-SANEX, GANEX, TRUSPEAK, ALSEP), this combination features only monofunctional extractants with high solubility limits and comparatively low molar mass. Selective actinide stripping from the loaded extractant phase is done using a glycine-buffered solution containing N-(2-hydroxyethyl)ethylenediaminetriacetic acid (HEDTA) or triethylenetetramine-N,N,N',N'',N''',N'''-hexaacetic acid (TTHA). Lastly, the results reported provide evidence for simplified interactions between the two extractants and demonstrate a pathway toward using mixed monofunctional extractants to separate trivalent actinides (An) from fission product lanthanides (Ln).

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

Prioritizing Scientific Data for Transmission

A software system has been developed for prioritizing newly acquired geological data onboard a planetary rover. The system has been designed to enable efficient use of limited communication resources by transmitting the data likely to have the most scientific value. This software operates onboard a rover by analyzing collected data, identifying potential scientific targets, and then using that information to prioritize data for transmission to Earth. Currently, the system is focused on the analysis of acquired images, although the general techniques are applicable to a wide range of data modalities. Image prioritization is performed using two main steps. In the first step, the software detects features of interest from each image. In its current application, the system is focused on visual properties of rocks. Thus, rocks are located in each image and rock properties, such as shape, texture, and albedo, are extracted from the identified rocks. In the second step, the features extracted from a group of images are used to prioritize the images using three different methods: (1) identification of key target signature (finding specific rock features the scientist has identified as important), (2) novelty detection (finding rocks we haven t seen before), and (3) representative rock sampling (finding the most average sample of each rock type). These methods use techniques such as K-means unsupervised clustering and a discrimination-based kernel classifier to rank images based on their interest level.

Castano, Rebecca↗

Real-World Driving Features for Identifying Intelligent Driver Model Parameters

Driver behavior models play a significant role in representing different driving styles and the associated relationships with traffic patterns and vehicle energy consumption in simulation studies. The models often serve as a proxy for baseline human driving when assessing energy-saving strategies that alter vehicle velocity. Such models are especially important in connectivity-enabled energy-saving strategy research because they can easily adapt to changing driving conditions like posted speed limits or change in traffic light state. While numerous driver models exist, parametric driver models provide the flexibility required to represent variability in real-world driving through different combinations of model parameters. These model parameters must be informed by a representative set of parameter values for the driver model to adequately represent a real-world driver. It stands to reason that determining the parameter values from real-world driving data would serve the purpose of representing a real-world driver. Although the published literature is replete with techniques and consequences of using real-world driving data to determine parameter values for parametric driver models, none have explored them in the context of using shorter driving features where the parameter values may change over the course of a single trip for the same driver. In this study we consider the “intelligent driver model” (IDM) as our driver behavior model and use real-world driving data from the Transportation Secure Data Center (TSDC) maintained at the National Renewable Energy Laboratory (NREL). The TSDC includes real-world travel data from across the United States, from which NREL has created a wide range of driving routes consisting of road features such as speed limits, stop locations, and turn locations. The real-world driving data are categorized into different driving regimes and extracted into driving features. The driving features are then used to calibrate the parameter values for the IDM. The distribution of the parameters and the relationships among them are reported. The insights obtained from this study enable judicious usage of IDM or similar parametric driver models to represent baseline human driver behavior in simulations.

27 ARPA - Advanced Research Projects Agency-Energy↗

Real-World Driving Features for Identifying Intelligent Driver Model Parameters: Preprint

Driver behavior models play a significant role in representing different driving styles and the associated relationships with traffic patterns and vehicle energy consumption in simulation studies. The models often serve as a proxy for baseline human driving when assessing energy-saving strategies that alter vehicle velocity. Such models are especially important in connectivity-enabled energy-saving strategy research because they can easily adapt to changing driving conditions like posted speed limits or change in traffic light state. While numerous driver models exist, parametric driver models provide the flexibility required to represent variability in real-world driving through different combinations of model parameters. These model parameters must be informed by a representative set of parameter values for the driver model to adequately represent a real-world driver. It stands to reason that determining the parameter values from real-world driving data would serve the purpose of representing a real-world driver. While the published literature is replete with techniques and consequences of using real-world driving data to determine parameter values for parametric driver models, none have explored them in the context of using shorter driving features where the parameter values may change over the course of a single trip for the same driver. In this study we consider the “Intelligent Driver Model” (IDM) as the driver behavior model to explore and real-world driving data from the Transportation Secure Data Center (TSDC) maintained at the National Renewable Energy Laboratory (NREL). The TSDC includes real-world travel data from across the United States, from which NREL has created a wide range of driving routes consisting of road features such as speed limits, stop locations and turn locations. The real-world driving data are categorized into different driving regimes and extracted into driving features. The driving features are then used to calibrate the parameter values for the IDM. The distribution of the parameters and the relationships among them are reported. The insights obtained from this study enable judicious usage of IDM or similar parametric driver models to represent baseline human driver behavior in simulations.

27 ARPA - Advanced Research Projects Agency-Energy↗

Optical Spectroscopic Investigation of Hexavalent Actinide Ions in n-Dodecane Solutions of Tri-butyl Phosphate

The extraction of hexavalent actinides An(VI) by tri-butyl phosphate (TBP) was investigated by electronic absorption and vibrational spectroscopies. Through a series of spectral subtractions, vibrational spectra associated with TBP, TBP–HNO3 adducts, and An(VI)–TBP complexes could be isolated. Investigation of U(VI) extracts indicated spectral features consistent with the formation of the expected [UO2(NO3)2(TBP)2] complex, but spectral features of other species were clearly evident. Likewise, multiple species were evident in the electronic absorption and vibrational spectra of TBP phases generated by extraction of Pu(VI). Although definitive characterization of the additional species formed could not be achieved in this work, it is hypothesized that they contain 3:1 TBP-to-An(VI) stoichiometry.

Lumetta, Gregg J.↗

Interpretable Machine Learning Models for Autonomous Characterization of Analogue Ocean World Seawater Chemistry and Biosignature Potential Using Isotope Ratio Data

Background: Future missions to ocean worlds, such as Enceladus and Europa, will attempt to characterize the subsurface seawater chemistry and assess the potential for life. Such missions will be equipped with capabilities to precisely measure volatile isotopes in plumes, atmospheres, and exospheres. Motivation: While large isotopic fractionations can indicate a biological source, there are signatures resulting from abiotic geochemical processes that mimic isotopic biosignatures. While machine learning (ML) has the potential to disentangle competing effects and biotic mimicry, high-dimensional isotope ratio mass spectrometry (IRMS) data is likely to contain noise/irrelevant features and involve complex statistical interactions that make human inference and interpretation difficult. Further, ML predictions with as far-reaching implications as an extraterrestrial biosignature on an ocean world requires the use of interpretable models (i.e., not “black box” models) with physically and mathematically meaningful feature spaces along with false positive diagnostics. Methods: We use volatile CO2 IRMS data of analogue ocean world seawaters to validate an ML approach to provide biogeochemical context for biosignature detection. We employ a feature selection method called nearest-neighbor projected distance regression (NPDR) that detects statistical interactions and helps elucidate the mechanisms of the Random Forest classification models. Results: We train and validate predictive ML models on volatile CO2 IRMS data of analogue ocean world seawaters to predict major salt components (e.g., MgSO4, NaHCO3), pH, ionic strength, and the presence of biosignatures. Features derived from IRMS measurements are augmented with extracted time-series features. Our results show high test accuracy and interpretability, which is increased by interaction network visualization, sample-wise variable importance scores, and single-sample class probability estimates. We demonstrate an ML mission software solution that triggers autonomous data transmission and biogeochemical sample prediction.

geochemistry↗

A spectral feature design system for the HIRIS/MODIS era

A spectral feature design system for high-dimensional multispectral data is described. This system utilizes hard-limited or infinitely clipped optimal transforms and canonical analysis to extract the spectral features for data volume reduction and classification purposes. The design procedure is intended to be application-specific in order to make it maximally effective for each use. Although it could be used in a variety of circumstances, the procedure was designed with satellite data collection in mind, such as will be needed with the High-Resolution Imaging Spectrometer (HIRIS), a land-oriented Earth observational sensor intended for launch in the mid-1990s. The computation required for the steps prior to the actual satellite data collection are straightforward and could be done with readily available subroutines. The procedure is also defined in such a way as to require only very simple onboard calculations. The tests reported provide substantial data volume reduction in the satellite-to-Earth downlink and subsequent computation phases, while maintaining satisfactory classification accuracy.

Chen, Chih-Chien Thomas↗