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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 937 records · Page 52
All sourcesNASA NTRSDOE OSTI
NASA NTRS1989

Ada compiler evaluation on the Space Station Freedom Software Support Environment project

This paper describes the work in progress to select the Ada compilers for the Space Station Freedom Program (SSFP) Software Support Environment (SSE) project. The purpose of the SSE Ada compiler evaluation team is to establish the criteria, test suites, and benchmarks to be used for evaluating Ada compilers for the mainframes, workstations, and the realtime target for flight- and ground-based computers. The combined efforts and cooperation of the customer, subcontractors, vendors, academia and SIGAda groups made it possible to acquire the necessary background information, benchmarks, test suites, and criteria used.

Badal, D. L.↗
NASA NTRS1994

Acute, 2-week, and 13-week inhalation toxicity studies on dimethylethoxysilane vapor in Fischer 344 rats

Dimethylethoxysilane (DMES), a volatile liquid, is used by NASA to waterproof the heat-protective silica tiles and blankets on the Space Shuttle. Acute, 2-wk, and 13-wk inhalation exposures to DMES vapor were conducted in male and female Fischer 344 rats. In the acute study, rats were exposed to 4000, 2000, 1000, 500, or 0 (control) ppm DMES for 4 h and observed for 14 days. There were no deaths. Narcosis and ataxia were observed in rats of the two highest concentrations only. These signs disappeared within 1 h following exposure. There were no DMES-related gross or microscopic tissue lesions in rats of all exposure groups. In the 2-wk study, rats were exposed for 6 h/day, 5 days/wk to 3000, 1000, 300, 100, or 0 ppm DMES. During exposure, narcosis was observed in rats of the 3000 and 1000 ppm groups. There was a mild decrease in body weight gain in rats of the 3000 ppm group. A decrease in platelet count, an increase in bile acids, and reduced weights of the thymus, testis, and liver were observed in rats of the 3000 ppm group. Microscopically, hypospermatogenesis and spermatid giant cells were observed in the seminiferous tubules of the testes of rats exposed to 3000 ppm DMES. In the 13-wk study, rats were exposed 6 h/day, 5 days/wk to 2000, 600, 160, 40, or 0 ppm DMES. During exposure, rats of the 2000 ppm group exhibited mild narcosis and loss of startle reflex. Recovery from these central nervous system signs was rapid. Body weights were mildly decreased for rats of the 2000 ppm group. There were no exposure-related effects in hematology, serum chemistry, or urinalysis. Female rats of the 2000 ppm group had delayed estrous cycles (6 days compared to 5 days in control rats). Noteworthy organ weight changes in rats of the 2000 ppm group included decreases in thymus, liver, and testicular weights; however, pathologic lesions were observed in the testes only. Sperm motility, epididymal sperm count, and testicular spermatid count were dramatically reduced. Microscopic lesions included degeneration of the seminiferous tubular cells, pyknosis or absence of germ cells, and hypospermia in the epididymis. Rats of the 600 ppm group had a slight decrease in thymic weight and a transient decrease in body weight. Results of the acute, 2-wk, and 13-wk inhalation studies indicate DMES concentrations of 1000 ppm and higher produce narcosis that rapidly disappears following exposure. Repeated exposure of rats to DMES at either 3000 ppm for 2 wk or 2000 ppm for 13 wk caused testicular atrophy and hypospermia in male rats. Female rats exposed to 2000 ppm for 13 wk had delayed estrous cycles. Toxicological effects in rats of the 600 ppm group were minimal and equivocal. The 160 ppm concentration was a no-observable-effect level (NOEL) for 13 wk of exposure to DMES.

NASA Discipline Number 04-10↗
NASA NTRS1977

Pump/Control System Minimum Operating Cost Testing

A preliminary evaluation of pump performance was initiated to determine the efficiencies of an arbitrary group of small pumps. Trends in factors affecting energy usage in typical prime movers which might be used in liquid transport solar systems were assessed. Comparisons of centrifugal pump efficiencies were made from one manufacturer to another. Tests were also made on two positive-displacement pumps and comparisons with centrifugal pumps were observed.

Source record↗
NASA NTRS1998

Testing Planetary Rovers: Technologies, Perspectives, and Lessons Learned

Rovers are a vital component of NASA's strategy for manned and unmanned exploration of space. For the past five years, the Intelligent Mechanisms Group at the NASA Ames Research Center has conducted a vigorous program of field testing of rovers from both technology and science team productivity perspective. In this talk, I will give an overview of the the last two years of the test program, focusing on tests conducted in the Painted Desert of Arizona, the Atacama desert in Chile, and on IMG participation in the Mars Pathfinder mission. An overview of autonomy, manipulation, and user interface technologies developed in response to these missions will be presented, and lesson's learned in these missions and their impact on future flight missions will be presented. I will close with some perspectives on how the testing program has affected current rover systems.

Thomas, Hans↗
DOE OSTI2020

Scoping Analysis of Sodium Cooled Fast Spectrum Test Reactor Cores

A team from the national laboratories conducted a study that assessed advanced reactor technology options and the irradiation needs of a broad group of stakeholders. This identified a gap in the fast neutron irradiation capability - the need for a test reactor that can deliver high neutron fluxes of fast neutrons. The study compared fast and thermal neutron irradiation technology options based on technology maturity and the ability to meet strategic objectives, along with pathways to deployment and tradeoffs in mission. It also provided a recommendation on specific technology options to address the current gap in fast neutron irradiation capabilities. In this context, a detailed scope of work was prepared that pertains to a trade study focusing on the core of a fast neutron spectrum test reactor. This report presents the main results obtained by a team of Argonne National Laboratory (ANL) and Idaho National Laboratory (INL) scientists. It aims at developing an overall understanding of how the various areas important to the design and successful operation of such a facility interact with one another. Developing a sense of the relevant sensitivities at a systems level creates an understanding of where and how margins may be available to improve performances (e.g., flux level, capacity factor, and thermal hydraulic limits). Emphasis is given to the reactor (core design options and safety) and its fuel cycle (fuel supply and fabrication, as well as spent fuel management).

22 GENERAL STUDIES OF NUCLEAR REACTORS↗
DOE OSTI2017

Bcl-2 expression is essential for development and normal physiological properties of tooth hard tissue and saliva production

Background: Apoptosis plays a fundamental role in appropriate tissue development and function. Although expression of Bcl-2 has been reported during tooth and submandibular gland (SMG) development, the physiological role Bcl-2 plays during these processes has not been addressed. This study was performed to evaluate the impact of Bcl-2 expression on the formation and properties of tooth hard tissue, and saliva production. Methods: Twenty-four mice (12 males and 12 females) were divided into three groups of eight (n=8): group A (Bcl-2 +/+), group B (Bcl-2 +/-), and group C (Bcl-2 -/-) and subjected to micro-CT analyses. The mineral content of first molars was analyzed by X-Ray diffraction (XRD) and scanning electron microscopy (SEM) color dot map. The surface microhardness was determined by Vickers test on labial surfaces of incisors. Saliva was collected from different groups of mice after subcutaneous injection of pilocarpine. Results: Samples from Bcl-2 -/- mice showed significantly smaller micro-CT values, lower and poor crystallinity of hydroxyapatite (HA), and lowest surface micro hardness. SMG from Bcl-2 -/- mice showed remarkable reduction in size, consistent with reduced saliva accumulation. Conclusions: The absence of Bcl-2 expression in SMG did not affect the expression of other Bcl-2 family members. Thus, Bcl-2 expression influence on the formation and properties of tooth hard tissue, and saliva accumulation. Significance: Bcl-2 expression has a significant impact on the mineralogical content of enamel crystals of tooth structure. Lack of Bcl-2 expression led to impaired production of enamel ACP crystals. - Highlights: • Lack of Bcl-2 expression led to impaired production of enamel ACP crystals. • Germline deletion of Bcl-2 reduced the surface microhardness of enamel. • Bcl-2 expression is vitally important for SMG function and saliva production. • Lack of Bcl-2 expression was not compensated by expression of other Bcl-2 family members.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2023

Organic preservation of vase‐shaped microfossils from the late Tonian Chuar Group, Grand Canyon, Arizona, USA

Abstract Vase‐shaped microfossils (VSMs) are found globally in middle Neoproterozoic (800–730 Ma) marine strata and represent the earliest evidence for testate (shell‐forming) amoebozoans. VSM tests are hypothesized to have been originally organic in life but are most commonly preserved as secondary mineralized casts and molds. A few reports, however, suggest possible organic preservation. Here, we test the hypothesis that VSMs from shales of the lower Walcott Member of the Chuar Group, Grand Canyon, Arizona, contain original organic material, as reported by B. Bloeser in her pioneering studies of Chuar VSMs. We identified VSMs from two thin section samples of Walcott Member black shales in transmitted light microscopy and used scanning electron microscopy to image VSMs. Carbonaceous material is found within the internal cavity of all VSM tests from both samples and is interpreted as bitumen mobilized from Walcott shales likely during the Cretaceous. Energy dispersive X‐ray spectroscopy (EDS) and wavelength dispersive X‐ray spectroscopy (WDS) reveal that VSM test walls contain mostly carbon, iron, and sulfur, while silica is present only in the surrounding matrix. Raman spectroscopy was used to compare the thermal maturity of carbonaceous material within the samples and indicated the presence of pyrite and jarosite within fossil material. X‐ray absorption spectroscopy revealed the presence of reduced organic sulfur species within the carbonaceous test walls, the carbonaceous material found within test cavities, and in the sedimentary matrix, suggesting that organic matter sulfurization occurred within the Walcott shales. Our suite of spectroscopic analyses reveals that Walcott VSM test walls are organic and sometimes secondarily pyritized (with the pyrite variably oxidized to jarosite). Both preservation modes can occur at a millimeter spatial scale within sample material, and at times even within a single specimen. We propose that sulfurization within the Walcott Shales promoted organic preservation, and furthermore, the ratio of iron to labile VSM organic material controlled the extent of pyrite replacement. Based on our evidence, we conclude that the VSMs are preserved with original organic test material, and speculate that organic VSMs may often go unrecognized, given their light‐colored, translucent appearance in transmitted light.

58 GEOSCIENCES↗
NASA NTRS2019

Design Guide for Bearings Used in Cryogenic Turbopumps and Test Rigs

Cryogenic bearings are a unique and specialized area of the overall group of bearings that are used every day in industrial and aerospace applications. Cryogenic bearings operate in a unique environment that is not experienced by most bearing applications. The high speeds of turbomachinery, flow of cryogenic coolants, use of nonstandard materials, and lack of lubrication place unique demands on cryogenic bearings that must be met for the safety and success of the mission. To meet the goals of safety and success, requirements are put on the designer, manufacturer, and user that are not normally applied to off-the-shelf bearings. The designer has to have knowledge of the operating conditions, rotational speeds, loads, stresses, installation methods, inspection criteria, dimensional requirements, and design and analytical tools. The manufacturer needs to be aware of the materials used for cryogenic bearings, special heat treatments required, cleanliness of the processes, and inspection techniques to ensure a good product. The user needs to be aware of the safe handling practices to eliminate corrosion and debris, correct installation and removal procedures, pre- and post-test inspections, and the documentation that follow the bearings. This guide is based on the experiences of engineers at NASA Marshall Space Flight Center (MSFC) that have been involved in bearing research and testing along with specific bearing references that have been written. It is not meant to be a bearing design textbook for cryogenic bearing applications. These are available from many authors. Its purpose is to help the designer, manufacturer, or user in the application of cryogenic bearings to better understand the requirements placed on these bearings.

H. G. Gibson↗
NASA NTRS2024

Integration of Automated Systems Test Campaign NC-IAS

NASA’s 2022 strategic plan included the goal to catalyze economic growth and drive innovation in the aviation industry, and to address challenges in air transportation and airspace management within the National Airspace System (NAS). The Aeronautics Research Mission Directorate (ARMD) specifically was tasked with leading aviation innovation to enable safe and sustainable air transportation through revolutionary vehicle advances and efficient flight operations. As a part of meeting these objectives and advancing air mobility concepts, NASA initiated the National Campaign (NC) in the Advanced Air Mobility (AAM) Project within the Airspace Operations and Safety Program (AOSP). The NC was designed to support operational demonstrations with industry as well as the research and development needed to support NASA-led research flight demonstrations. Within NC, the Integration of Automated Systems (IAS), an NC activity, tested and evaluated flight deck automation and airspace operations management functions needed to enable Urban Air Mobility (UAM) operations. This was accomplished through a partnership with Sikorsky Aircraft (specifically Sikorsky Innovations), a Lockheed Martin company, and DARPA (Defense Advanced Research Projects Agency), by leveraging two automation-enabled helicopters equipped with unique capabilities that enabled NASA to develop and test two-ship conflict encounters to demonstrate flight path management and hazard avoidance technologies. The enabler in this testing was NASA-developed “Middleware” (MW) software (also known as Expandable Variable Autonomy Architecture, or EVAA), which among other things allowed multiple algorithms to be incorporated into one software build that was hosted on the dissimilar-type Sikorsky helicopters. The IAS test campaign period of performance was from March 2022 through October 2023 and was structured as a phased, or spiral, approach that ultimately led to the first-ever demonstration of two-ship UAM/AAM operations designed to safely choreograph specific conflict encounters and mission scenarios to test the research algorithms for strategic and tactical aircraft deconfliction. Lessons learned are included in the body of the report. Data collected will be used to inform FAA and industry standards groups on the increasingly automated systems needed for future AAM operations. The test encounters developed for these flight tests were proven to be highly predictable, repeatable, and safely exercised flight path planning and Detect and Avoid (DAA) algorithms. These same test encounters should be leveraged by future flight test campaigns to verify that operational safety is not compromised as the AAM architecture matures. Next steps include repeating similar encounters using unmanned aircraft carrying DAA sensors in the National Airspace.

AAM↗
NASA NTRS2012

Whole Module Offgas Test Report: Space-X Dragon Module

Between 7 April and 11 April 2012 a chemist from the JSC Toxicology Group acquired samples of air in 500 ml evacuated canisters from the sealed Dragon Module at the Space-X facility at KSC. Three samples were taken of facility air (two before the test and one after the test), and a total of 9 samples were taken from the sealed module in triplicate at the following times: 0 hours, 48 hours, and 96 hours. The module contained 470 kg, which was 100% of the mass to be launched. Analytical data contained in the Toxicology Group Report (attached) show that the ambient facility air was clean except for almost 9 milligrams per cubic meter of isopropanol (IPA) in the sample taken at the end of the test. Space-X must ensure that IPA is not introduced into the module before it is sealed for launch. Other minor contaminants in the ambient air included the following: perfluoro(2-methyl)pentane and hexamethylcyclotrisiloxane. The first-acquired samples of each triplicate from the module were not analyzed. Analyses of pairs of samples that were taken during the test show excellent agreement between the pairs and a linear increase in the T-values during the 4 days of the test (figure below). The rate of increase averaged 0.124 T units per day. If the time from last purge of the module on the ground to crew first entry on orbit is 10 days, then the T value at first entry should be less than 1.2 units, which is well below the criterion of 3.0 for consideration of additional protection of the crew from offgas products. The primary contributors were as follows: trimethylsilanol (0.057), fluorotrimethylsilane (0.047), acetaldehyde (0.004), hexamethylcyclopentasiloxane (0.003), and toluene (0.002).

James, John T.↗
DOE OSTI2018

Customized multi-group cross section generation with NJOY for discrete ordinates X-ray computed tomography and radiography simulation - 25589

The purpose of this work was to explore the creation of photo-atomic multi-group cross section libraries to be used with a software package DOCTORS (Discrete Ordinates Computed Tomography and Radiography Simulator). This software solves the linear Boltzmann equation using the discrete ordinates method. To create these libraries, NJOY2016 was used, creating both fine and broad energy multi-group cross section files. The cross section's accuracy was tested against an equivalent Monte Carlo simulation using MCNP6. Two simulation geometries were used. The first, a cylindrical water phantom with a single source projection placed in front, simulating an X-ray radiography. The second used the same water phantom with 16 cone beam sources placed evenly around the phantom to simulate a computed tomography (CT) scan. The accuracy of the fine energy multi-group cross sections when used in DOCTORS has been verified. The accuracy of the broad energy multigroup cross sections when used in DOCTORS shows that more work must be done before they can be used reliably. (authors)

61 RADIATION PROTECTION AND DOSIMETRY↗
NASA NTRS1999

Quantitative Interpretation of Optical Emission Sensors for Microgravity Experiments

Microgravity flight experiments uniquely test our knowledge and understanding of the coupling between chemistry and fluid mechanics. However, compared to ground based laboratory experiments the number of useful diagnostic tools suitable for microgravity environments is severely limited by the space, weight, power consumption, and operator complexity requirements. One of the available tools is the observation of optical emission, and total emission has already proven useful for observations of stable "flame balls" on the space shuttle. Wavelength resolved tomographic measurements of flame emission offer the promise of diagnostics to test our understanding of flame chemistry and structure. Individual emissions from electronically excited radicals, e.g., CH*, OH*, and C2*, can be identified in a methane/air flame. Spatially resolved measurements of the intensity of this resolved optical emission from a specific excited molecule enable chemically resolved flame structure studies. Wavelength resolved emission measurements to determine such structure in diffusion flames are being readied for flight experiments by a group at Yale headed by Profs. Smooke and Long. A quantitative relationship between emission intensity and flame properties, as expressed by a flame model, is needed for species specific optical emission measurements to fulfill its promise. The Yale group compared models and measurements of optical emission in laboratory tests at 1-g. Unfortunately, these experiments show disagreement between measurement and state-of-the-art flame models by over a factor of 50. Therefore, an improved chemical mechanism for optical emission from flames is needed to enable quantitative tests of microgravity flame models. The connection between excited state emission and flame chemistry is not yet adequate.

Jeffries, Jay B.↗
DOE OSTI2018

Cu- and Zr-based metal organic frameworks and their composites with graphene oxide for capture of acid gases at ambient temperature

Highlights: • Incorporation of GO in Cu- and Zr-based MOFs resulted in additional porosity at the interstitial MOF/GO spaces. • The UiO-66-NH{sub 2}/GO composite exhibited enhanced CO{sub 2} capacity at higher pressures. • CO{sub 2}/N{sub 2} selectivity of HKUST-1/GO was higher compared to pure HKUST-1. • The HKUST-1 crystallites in the presence of GO exhibited enhanced H{sub 2}S sorption kinetics. • The UiO-66 based adsorbents were more stable in humidity conditions than the HKUST-1 based ones. - Abstract: Capture of acid gases (CO{sub 2} and H{sub 2}S) by liquid solvent absorption is the common industrial practice, yet capture relying on solid adsorbents is increasingly gaining interest as potential alternative towards less energy-demanding operations. Herein, we developed and examined various metal organic frameworks (MOFs) bearing Cu- and Zr- metal clusters and their composites with graphene oxide (GO), and evaluated their performance for CO{sub 2} and H{sub 2}S adsorption. Specifically, UiO-66, UiO-66-NH{sub 2}, HKUST-1, and their GO composites were grown, subjected to structural, morphological, and textural characterization, and subsequently evaluated for their adsorption capacity and selectivity at ambient temperature. The crystallinity of the parent MOFs was preserved upon in-situ growth of the MOF/GO composites, while incorporation of GO yielded uniformly-shaped and well-dispersed MOF crystals resulting in enhanced sorption kinetics, and increased the pore volume compared to pure MOFs due to additional porosity formed in the interstitial spaces between the MOF crystallites and the GO flakes. To this extent, the interplay between additional porosity and pore functionalities in the competitive CO{sub 2} and N{sub 2} adsorption was investigated. UiO-66-NH{sub 2} exhibited enhanced CO{sub 2} capacity (3.07 mmol/g at 25 °C and 4 bar) and the highest CO{sub 2}/N{sub 2} selectivity (167 at 1 bar) among the tested MOFs, due to the presence of the amine functional groups in the organic linker that enhanced affinity with CO{sub 2}. At increased pressures, the UiO-66-NH{sub 2}/GO composite exhibited higher CO{sub 2} capacity compared to pure UiO-66-NH{sub 2}, which is attributed to activation of the additional porosity between the MOF crystallites and the GO layers. HKUST-1/GO selectivity was also enhanced compared to HKUST-1 in all pressures tested. Under humid environment, the UiO-66 based structures were relatively stable in contrast to the HKUST-1 ones that underwent gradual degradation. These composites offer functionalization tunability due to the presence of both MOF and GO counterparts for targeted gas capture applications.

36 MATERIALS SCIENCE↗
NASA NTRS2019

The Cognition and Fine Motor Skills Test Batteries: Normative Data and Interdependencies

Space mission success and safety relies upon astronaut functional state. Since spaceflight stressors affect cognitive processing and fine motor skills, NASA requires that measures of performance of these things remain within clinically accepted values (NASA STD 3001). NASA is in the process of developing two test batteries for the assessment of crew cognitive and fine motor skills before, during and after spaceflight. Toward that goal, the current project collected normative scores in 91 “astronaut-like” military and civilian pilots. The Cognition Test Battery (CTB) contains ten sub-tests that measure a range of cognitive abilities. For five of the ten CTB sub-tests, we propose scores to improve the battery’s sensitivity. Among the ten sub-tests, response times were more highly correlated than accuracy scores. Principle component analysis of the correlations revealed that the first response time factor could explain over 40% of the total variance and appeared to represent the tendency of observers to try to respond more quickly. The first accuracy factor (explaining only 20%) gave a high weight to the higher level cognitive sub-tests and a negative weight to tasks associated with motor and lower level cognitive processing. The Fine Motor Skills (FMS) test battery contains four sub-tests (Tracking, Pointing, Tracing, Rotating) performed on an Apple iPad tablet computer. Principle component analysis on the sub-test response time correlations revealed that the first two factors accounted for ~80% of the variance in performance. The first component captured overall speed on all four of the sub-tests. The second factor separated the sub-tasks into two groups (Drag-Point vs Trace-Rotate). Previous work found the first group response times correlated with that of a standard peg board task, while those of the other group did not. Correlations were computed between the first FMS factor and the response time and accuracy scores from each CTB sub-task. Performing fine motor behaviors rapidly was significantly correlated with the ability to perform many of the CTB sub-tests rapidly. This ability cannot be simple motor speed since scores on the Psychomotor Vigilance Test (PVT) subtask did not correlate with the ability to perform the other tasks rapidly. Speed on fine motor skills correlated significantly with accuracy on the short-term-memory sub-test. We hypothesize that eye movements, which can be regarded as a fine motor skill, may explain this relationship.

cognition↗
DOE OSTI2025

A harmonized protocol to assess the single-cell performance of proton exchange membrane water electrolyzers

The harmonization of testing protocols for proton exchange membrane (PEM) electrolyzers is essential for ensuring accurate and reliable performance assessments and accelerating the development of hydrogen production technologies. This protocol provides a structured approach to PEM electrolyzer setup and testing, incorporating key considerations for test station design and single-cell characterization techniques. Polarization curves and electrochemical impedance spectroscopy (EIS) are detailed, along with best practices from academic and industry research groups to enhance data accuracy and comparability. By addressing material variability and harmonizing testing methodologies, this framework enables more precise evaluations of membrane electrode assemblies and electrolyzer components. Harmonized protocols not only streamline development efforts but also foster collaboration across institutions, ultimately supporting the commercialization of hydrogen solutions through improved stack efficiency and durability.

08 HYDROGEN↗
NASA NTRS2002

Apolipoprotein E expression and behavioral toxicity of high charge, high energy (HZE) particle radiation

Apolipoprotein E (apoE) is a lipid binding protein that plays an important role in tissue repair following brain injury. In the present studies, we have investigated whether apoE affects the behavioral toxicity of high charge, high energy (HZE) particle radiation. METHODS: Sixteen male apoE knockout (KO) mice and sixteen genetically matched wild-type (WT) C57BL mice were used in this experiment. Half of the KO and half of the WT animals were irradiated with 600 MeV/amu iron particles (2 Gy whole body). The effect of irradiation on motor coordination and stamina (Rotarod test), exploratory behavior (open field test), and spatial working and reference memory (Morris water maze) was assessed. ROTAROD TEST: Performance was adversely affected by radiation exposure in both KO and WT groups at 30 d after irradiation. By 60 d after radiation, the radiation effect was lost in WT, but still apparent in irradiated KO mice. OPEN FIELD TEST: Radiation reduced open field exploratory activity 14, 28, 56, 84, and 168 d after irradiation of KO mice, but had no effect on WT mice. MORRIS WATER MAZE: Radiation adversely affected spatial working memory in the KO mice, but had no discernible effect in the WT mice as assessed 180 d after irradiation. In contrast, irradiated WT mice showed marked impairment of spatial reference memory in comparison to non-irradiated mice, while no effect of radiation was observed in KO mice. CONCLUSIONS: These studies show that apoE expression influences the behavioral toxicity of HZE particle radiation and suggest that apoE plays a role in the repair/recovery from radiation injury of the CNS. ApoE deficiency may exacerbate the previously reported effects of HZE particle radiation in accelerating the brain aging process.

Non-NASA Center↗
NASA NTRS1995

Smoke detection in low-G fires

Fires in spacecraft are considered a credible risk. To respond to this risk, NASA flew fire detectors on Skylab and the Space Shuttle (STS) and included them in the design for International Space Station Alpha (ISSA). In previous missions (Mercury, Gemini and Apollo), the crew quarters were so cramped that it was not considered credible that the astronauts could fail to observe a fire. The Skylab nodule included approximately 20 UV fire detectors. The space shuttle has 9 ionization detectors in the mid deck and flight deck and Spacelab has six additional ionization detectors. The planned detectors for ISSA are laser-diode, forward-scattering, smoke or particulate detectors. Current plans for the ISSA call for two detectors in the open area of the module and detectors in racks that have both cooling air flow and electrical power. Due to the complete absence of data concerning the nature of particulate and radiant emission from low-g fires, all three of these detector systems were designed based upon 1-g test data. As planned mission durations and complexity increase and the volume of spacecraft increases, the need for and importance of effective, crew independent, fire detection grows significantly. This requires more knowledge concerning low-gravity fires and how they might be detected. To date, no combustion-generated particulate samples have been collected for well-developed microgravity flames. All of the extant data come from drop tower tests and therefore only correspond to the early stages of a fire. The fuel sources were restricted to laminar gas-jet diffusion flames and rapidly overheated wire insulation. These gas-jet drop tower tests indicate, through thermophoretic sampling, that soot primaries and aggregates (groups of primary particles) in micro-g may be significantly larger than those in normal-g (ng). This raises new scientific questions about soot processes as well as practical issues for particulate detection/alarm threshold levels used in on-orbit smoke detectors. Furthermore, it is widely speculated but unverified that the aggregates will grow to very large scales in a microgravity fire of longer duration than available on the ground. Preliminary tests in the 2.2 second drop tower suggest that particulate generated by overheated wire insulation will also be larger in microgravity than in normal gravity. TEM grids downstream of the fire region in the WIF experiment as well as visual observation of long string-like aggregates, further confirm this suggestion. The combined impact of these limited results and theoretical predictions is that direct knowledge of low-g combustion particulate as opposed to extrapolation from 1-g data is needed for a more confident design of smoke detectors for spacecraft.

Urban, David L.↗