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At least 919 records · Page 51

Deep-learning-aided forward optical coherence tomography endoscope for percutaneous nephrostomy guidance

Percutaneous renal access is the critical initial step in many medical settings. In order to obtain the best surgical outcome with minimum patient morbidity, an improved method for access to the renal calyx is needed. In our study, we built a forward-view optical coherence tomography (OCT) endoscopic system for percutaneous nephrostomy (PCN) guidance. Porcine kidneys were imaged in our experiment to demonstrate the feasibility of the imaging system. Three tissue types of porcine kidneys (renal cortex, medulla, and calyx) can be clearly distinguished due to the morphological and tissue differences from the OCT endoscopic images. To further improve the guidance efficacy and reduce the learning burden of the clinical doctors, a deep-learning-based computer aided diagnosis platform was developed to automatically classify the OCT images by the renal tissue types. Convolutional neural networks (CNN) were developed with labeled OCT images based on the ResNet34, MobileNetv2 and ResNet50 architectures. Nested cross-validation and testing was used to benchmark the classification performance with uncertainty quantification over 10 kidneys, which demonstrated robust performance over substantial biological variability among kidneys. ResNet50-based CNN models achieved an average classification accuracy of 82.6%±3.0%. The classification precisions were 79%±4% for cortex, 85%±6% for medulla, and 91%±5% for calyx and the classification recalls were 68%±11% for cortex, 91%±4% for medulla, and 89%±3% for calyx. Interpretation of the CNN predictions showed the discriminative characteristics in the OCT images of the three renal tissue types. The results validated the technical feasibility of using this novel imaging platform to automatically recognize the images of renal tissue structures ahead of the PCN needle in PCN surgery.

Wang, Chen↗

Application of deep learning to single-shot gas-phase laser-induced breakdown spectroscopy

Single-shot fs laser-induced breakdown spectroscopy (LIBS) has the potential to capture ns-scale electrode desorption phenomena in pulsed power fusion drivers. However, the successful implementation of the diagnostic for this purpose is challenging, as it requires interpreting single-shot measurements collected from low-density gas mixtures. In this work, we demonstrate the efficacy of a Bayesian-optimized convolutional neural network (CNN) to interpret these measurements. We generated 256 distinct measurement conditions at relevant gas pressures ranging from 80–530 mTorr by mixing 100–250 sccm H 2 and 50–200 sccm CH 4 in increments of 10 sccm. Despite the considerable overlap between signals separated by 20 sccm, the CNN is able to predict the H 2 flow rate with a root-mean-square error (RMSE) of 15.9 sccm and the CH 4 flow rate with an RMSE of 12.0 sccm. The average relative prediction error is <9% for each gas and largely remains below or near 10%.

Brown, Nathan Parnell [Sandia National Lab. (SNL-N↗

Real-time image denoising of mixed Poisson–Gaussian noise in fluorescence microscopy images using ImageJ

Fluorescence microscopy imaging speed is fundamentally limited by the measurement signal-to-noise ratio (SNR). To improve image SNR for a given image acquisition rate, computational denoising techniques can be used to suppress noise. However, common techniques to estimate a denoised image from a single frame either are computationally expensive or rely on simple noise statistical models. These models assume Poisson or Gaussian noise statistics, which are not appropriate for many fluorescence microscopy applications that contain quantum shot noise and electronic Johnson–Nyquist noise, therefore a mixture of Poisson and Gaussian noise. In this paper, we show convolutional neural networks (CNNs) trained on mixed Poisson and Gaussian noise images to overcome the limitations of existing image denoising methods. The trained CNN is presented as an open-source ImageJ plugin that performs real-time image denoising (within tens of milliseconds) with superior performance (SNR improvement) compared to conventional fluorescence microscopy denoising methods. The method is validated on external datasets with out-of-distribution noise, contrast, structure, and imaging modalities from the training data and consistently achieves high-performance ( > <#comment/> 8 d B ) denoising in less time than other fluorescence microscopy denoising methods.

47 OTHER INSTRUMENTATION↗

UNNT: A novel Utility for comparing Neural Net and Tree-based models

The use of deep learning (DL) is steadily gaining traction in scientific challenges such as cancer research. Advances in enhanced data generation, machine learning algorithms, and compute infrastructure have led to an acceleration in the use of deep learning in various domains of cancer research such as drug response problems. In our study, we explored tree-based models to improve the accuracy of a single drug response model and demonstrate that tree-based models such as XGBoost (eXtreme Gradient Boosting) have advantages over deep learning models, such as a convolutional neural network (CNN), for single drug response problems. However, comparing models is not a trivial task. To make training and comparing CNNs and XGBoost more accessible to users, we developed an open-source library called UNNT (A novel Utility for comparing Neural Net and Tree-based models). The case studies, in this manuscript, focus on cancer drug response datasets however the application can be used on datasets from other domains, such as chemistry.

59 BASIC BIOLOGICAL SCIENCES↗

Deep learning classification of lipid droplets in quantitative phase images

We report the application of supervised machine learning to the automated classification of lipid droplets in label-free, quantitative-phase images. By comparing various machine learning methods commonly used in biomedical imaging and remote sensing, we found convolutional neural networks to outperform others, both quantitatively and qualitatively. We describe our imaging approach, all implemented machine learning methods, and their performance with respect to computational efficiency, required training resources, and relative method performance measured across multiple metrics. Overall, our results indicate that quantitative-phase imaging coupled to machine learning enables accurate lipid droplet classification in single living cells. As such, the present paradigm presents an excellent alternative of the more common fluorescent and Raman imaging modalities by enabling label-free, ultra-low phototoxicity, and deeper insight into the thermodynamics of metabolism of single cells.

59 BASIC BIOLOGICAL SCIENCES↗

Observations and Machine-Learned Models of Near-Surface Permafrost along the Koyukuk River, Alaska, USA

This dataset contains GeoTIFs (raster) and GeoPackages (vector) that map observations of near-surface permafrost and not-permafrost from a field campaign conducted near the village of Huslia, AK along the Koyukuk River and its floodplain in July 2018. These data were collected as part of a campaign to understand if and how permafrost impacts riverbank erosion. This problem cannot be assessed without knowing where permafrost exists. Permafrost was observed via frost probing (to a maximum depth of one meter), coring (to a maximum depth of two meters) and bank/bar excavations. An additional boat survey was performed wherein expert (Joel Rowland) judgment assessed the presence or absence of distinctive permafrost features (e.g., overhanging tundra mats, thermoerosional niching, ice wedges, active drainage of ice melt from soils). This dataset also contains the input features and results of two machine learning models (random forest and convolutional neural network) that extrapolate the observations to the full floodplain that may be useful for building, testing, or validating other machine-learned permafrost models. Permafrost data are provided as georasters of the same shape and geovectors (polylines/polygons) and are all projected into EPSG:32605. All data can be visualized with a GIS (QGIS, ArcGIS, etc.).

54 ENVIRONMENTAL SCIENCES↗

Deep Learning Denoising Applied to Regional Distance Seismic Data in Utah

Seismic waveform data are generally contaminated by noise from various sources. Suppressing this noise effectively so that the remaining signal of interest can be successfully exploited remains a fundamental problem for the seismological community. To date, the most common noise suppression methods have been based on frequency filtering. These methods, however, are less effective when the signal of interest and noise share similar frequency bands. Inspired by source separation studies in the field of music information retrieval (Jansson et al., 2017) and a recent study in seismology (Zhu et al., 2019), we implemented a seismic denoising method that uses a trained deep convolutional neural network (CNN) model to decompose an input waveform into a signal of interest and noise. In our approach, the CNN provides a signal mask and a noise mask for an input signal. The short-time Fourier transform (STFT) of the estimated signal is obtained by multiplying the signal mask with the STFT of the input signal. To build and test the denoiser, we used carefully compiled signal and noise datasets of seismograms recorded by the University of Utah Seismograph Stations network. Results of test runs involving more than 9000 constructed waveforms suggest that on average the denoiser improves the signal-to-noise ratios (SNRs) by ~5 db, and that most of the recovered signal waveforms have high similarity with respect to the target waveforms (average correlation coefficient of ~0.80) and suffer little distortion. Application to real data suggests that our denoiser achieves on average a factor of up to ~2-5 improvement in SNR over band-pass filtering and can suppress many types of noise that band-pass filtering cannot. For individual waveforms, the improvement can be as high as ~15 db.

58 GEOSCIENCES↗

Using Deep Learning to Derive Shear-Wave Velocity Models from Surface-Wave Dispersion Data

We present a new algorithm for derivations of 1D shear-wave velocity models from surface-wave dispersion data using convolutional neural networks (CNNs). The technique is applied for continental China and the plate boundary region in southern California. Different CNNs are designed for these two regions and are trained using theoretical Rayleigh-wave phase and group velocity images computed from reference 1D VS models. The methodology is tested with 3260 phase–group images for continental China and 4160 phase–group images for southern California. The conversions of these images to velocity profiles take ~23 s for continental China and ~30 s for southern California on a personal laptop with the NVIDIA GeForce GTX 1060 core and a memory of 6 GB. The results obtained by the CNNs show high correlation with previous studies using conventional methods. The effectiveness of the CNN technique makes this fast method an important alternative for deriving shear-wave velocity models from large datasets of surface-wave dispersion data.

Geochemistry & Geophysics↗

A Data-Driven Framework for Automated Detection of Aircraft-Generated Signals in Seismic Array Data Using Machine Learning

Abstract Ground motions associated with aircraft overflights can cover a significant portion of the seismic data collected by shallowly emplaced seismometers, such as new nodal and Distributed Acoustic Sensing systems. This article describes the first published framework for automated detection of aircraft on single channel and multichannel seismic data. The seismic data are converted to spectrograms in a sliding time window and classified as aircraft or nonaircraft in each window using a deep convolutional neural network trained with analyst-labeled data. A majority voting scheme is used to convert the output from the sequence of sliding time windows onto a decision time sequence for each channel and to combine the binary classifications on the decision time sequences across multiple channels. Precision, recall, and F-score are used to quantify the detection performance of the algorithm on nodal data using fourfold time-series cross validation. By applying our framework to data from the Sage Brush Flats nodal array in Southern California, we provide a benchmark performance and demonstrate the advantage of using an array of sensors.

Geochemistry & Geophysics↗

Identifying the quantum properties of hadronic resonances using machine learning

With the great promise of deep learning, discoveries of new particles at the Large Hadron Collider (LHC) may be imminent. Following the discovery of a new Beyond the Standard model particle in an all-hadronic channel, deep learning can also be used to identify its quantum numbers. Convolutional neural networks (CNNs) using jet-images can significantly improve upon existing techniques to identify the quantum chromodynamic (QCD) (‘color’) as well as the spin of a two-prong resonance using its substructure. Additionally, jet-images are useful in determining what information in the jet radiation pattern is useful for classification, which could inspire future taggers. These techniques improve the categorization of new particles and are an important addition to the growing jet substructure toolkit, for searches and measurements at the LHC now and in the future.

Filipek, Jakub↗

A Machine Learning Approach to the Detection of Ghosting Artifacts in Dark Energy Survey Images

Unwanted artifacts that often plague astronomical images arise from a number of sources that include imperfect optics, faulty image sensors, cosmic ray hits, and even airplanes and satellites. One major source that is dicult to avoid is known as ghosting, and is caused by the scattering and internal reflections of light o of the telescope’s mechanical and optical components. Detecting ghosting artifacts eciently in the large cosmological surveys that will acquire petabytes of data can be a daunting task. In this paper, we use data from the Dark Energy Survey to develop, train, and validate a machine learning model to detect ghosts based on convolutional neural networks. The model architecture and training procedure is discussed in detail, and the performance on the training and validation set presented. Testing is performed on data and results are compared with those from a ray-tracing algorithm. A proof-of-principle is demonstrated that shows promise for Stage IV surveys and beyond.

79 ASTRONOMY AND ASTROPHYSICS↗

Applying Machine Learning to the Classification of DC-DC Converters (Milestone 2 Deliverable Report)

Since extending the Autodetector to a convolutional neural network (CNN) machine learning classifier model, an effort has been executed to demonstrate its ability to distinguish not only a switching DC-DC converter as high voltage, but identify the make and model of a converter on which it was trained. This was achieved by collecting data in a noisy environment, pre-processing the time domain data to obtain composite images using a method that improves upon that of the prior research, then validating a trained CNN model to an accuracy of 100% on a selected candidate converter.

42 ENGINEERING↗

How Low Can You Go? Using Synthetic 3D Imagery to Drastically Reduce Real-World Training Data for Object Detection

Deep convolutional neural networks (DCNNs) currently provide state-of-the-art performance on image classification and object detection tasks, and there are many global security mission areas where such models could be extremely useful. Crucially, the success of these models is driven in large part by the widespread availability of high-quality open source data sets such as Image Net, Common Objects in Context (COCO), and KITTI, which contain millions of images with thousands of unique labels. However, global security relevant objects-of-interest can be difficult to obtain: relevant events are low frequency and high consequence; the content of relevant images is sensitive; and adversaries and proliferators seek to obscure their activities. For these cases where exemplar data is hard to come-by, even fine-tuning an existing model with available data can be effectively impossible. Recent work demonstrated that models can be trained using a combination of real-world and synthetic images generated from 3D representations; that such models can exceed the performance of models trained using real-world data alone; and that the generated images need not be perfectly realistic (Tremblay, et al., 2018). However, this approach still required hundreds to thousands of real-world images for training and fine tuning, which for sparse, global security-relevant datasets can be an unrealistic hurdle. In this research, we validate the performance and behavior of DCNN models as we drive the number of real-world images used for training object detection tasks down to a minimal set. We perform multiple experiments to identify the best approach to train DCNNs from an extremely small set of real-world images. In doing so, we: Develop state-of-the-art, parameterized 3D models based on real-world images and sample from their parameters to increase the variance in synthetic image training data; Use machine learning explainability techniques to highlight and correct through targeted training the biases that result from training using completely synthetic images; and Validate our results by comparing the performance of the models trained on synthetic data to one another, and to a control model created by fine-tuning an existing ImageNet-trained model with a limited number (hundreds) of real-world images.

97 MATHEMATICS AND COMPUTING↗

Reification of latent microstructures: On supervised unsupervised and semi-supervised deep learning applications for microstructures in materials informatics

Machine learning (ML), including deep learning (DL), has become increasingly popular in the last few years due to its continually outstanding performance. In this context, we apply machine learning techniques to "learn" the microstructure using both supervised and unsupervised DL techniques. In particular, we focus (1) on the localization problem bridging (micro)structure (localized) property using supervised DL and (2) on the microstructure reconstruction problem in latent space using unsupervised DL. The goal of supervised and semi-supervised DL is to replace crystal plasticity finite element model (CPFEM) that maps from (micro)structure (localized) property, and implicitly the (micro)structure (homogenized) property relationships, while the goal of unsupervised DL is (1) to represent high-dimensional microstructure images in a non-linear low-dimensional manifold, and (2) to discover a way to interpolate microstructures via latent space associating with latent microstructure variables. At the heart of this report is the applications of several common DL architectures, including convolutional neural networks (CNN), autoencoder (AE), and generative adversarial network (GAN), to multiple microstructure datasets, and the quest of neural architecture search for optimal DL architectures.

36 MATERIALS SCIENCE↗

Microseismic Event Denoising: Removal of Borehole Waves

The vertical borehole array at Farnsworth Unit, TX is used to monitor microseismic activity in the subsurface around the Carbon Capture and Sequestration (CCS) reservoir. The array consists of 16 3-component seismometers spaced vertically in a single borehole. Tube or borehole waves traveling up or down the borehole can corrupt signals of interest, such as microseismic events. A denoising convolutional neural network (DCNN) was trained to remove borehole waves from seismic waveforms of microseismic events for the purpose of reducing unwanted signal detections and better characterizing events of interest. This R&D leverages the work of Sandia colleague Rigo Tibi, who used a DCNN developed by Greg Beroza at Stanford University to improve the signal-to-noise ratio (SNR) of teleseismic events detected by the International Monitoring System.

58 GEOSCIENCES↗

Identifying precursors of daily to seasonal hydrological extremes over the USA using deep learning techniques and climate model ensembles

Focal Area(s): We focus on two areas of crosscutting interest for DOE: 1) predictability of extreme precipitation and drought in the USA and 2) the integration of climate models with new AI tools, such as convolutional neural networks (CNN) and methods to understand their output (e.g. layer-wise relevance propagation; LRP). This project fits into focus area 3 of this call for white paper using AI to gain insight from complex data, including explainable AI tools. Science Challenge: Predicting hydrological extremes is important due to their impacts on people, agriculture and infrastructure. This prediction is difficult due to the infrequent occurrence of extremes and their complexity. However, extreme events can be related to more predictable conditions in the ocean, such as El Nino, long-term soil moisture or large scale modes of climate variability, such as the North Atlantic Oscillation (NAO).

54 ENVIRONMENTAL SCIENCES↗

Insights into cosmological structure formation with machine learning.

Our modern understanding of cosmological structure formation posits that small matter density fluctuations present in the early Universe, as traced by the cosmic microwave background, grow via gravitational instability to form extended haloes of dark matter. A theoretical understanding of the structure, evolution and formation of dark matter haloes is an essential step towards unravelling the intricate connection between halo and galaxy formation, needed to test our cosmological model against data from upcoming galaxy surveys. Physical understanding of the process of dark matter halo formation is made difficult by the highly non-linear nature of the haloes' evolution. I describe a new approach to gain physical insight into cosmological structure formation based on machine learning. This approach combines the ability of machine learning algorithms to learn non-linear relationships, with techniques that enable us to physically interpret the learnt mapping. I describe applicatio ns of th e method, with the aim of investigating which aspects of the early universe density field impact the later formation of dark matter haloes. First I present a case where the process of halo formation is turned into a binary classification problem; the algorithm predicts whether or not dark matter `particles' in the initial conditions of a simulation will collapse into haloes of a given mass range. Second, I present its generalization to regression, where the algorithm infers the final mass of the halo to which each particle will later belong. I show that the initial tidal shear does not play a significant role compared to the initial density field in establishing final halo masses. Finally, I demonstrate that extending the framework to deep learning algorithms such as convolutional neural networks allows us to explore connections between the early universe and late time haloes beyond those studied by existing analytic approximations of halo collapse.

79 ASTRONOMY AND ASTROPHYSICS↗

Bridging Power System Protection Gaps with Data-driven Approaches

Protection is a critical function in power systems to avoid equipment damage, maintain personnel safety, and support system reliability. However, current protective relay technology cannot adequately protect equipment and personnel from effects of some events; these deficiencies are termed protection gaps. In this research, a data-driven approach is proposed to complement traditional protection technology and distinguish fault conditions from transients caused by normal operations. A convolutional neural network (CNN) based fault detection approach is implemented to achieve data translation invariance of the time-series input data. As a result, the data-driven method can accurately detect system faults despite variation and noise in the input data. In addition, using the CNN–based method avoids the complicated manual feature extraction procedure required by many traditional data-driven methods. The effectiveness of the proposed approach is tested on four kinds of protection gaps: high impedance faults, transformer/generator inter-turn faults, distribution system PV circuit faults, and the mis-operation situations of Zone 3 line protection relays operating under system stress. Finally, a transfer learning method is also proposed to address the common issue of data-driven methods for which real-world training data are scarce. Extensive study results demonstrate that the proposed approach can accurately bridge power system protection gaps.

24 POWER TRANSMISSION AND DISTRIBUTION↗