Temporal Changes in Astronauts’ Muscle and Cardiorespiratory Physiology Before, During, and After Spaceflight (CIPHER-SPACEPHYS)
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INTRODUCTION: Studies find that humans average approximately six hours of sleep per night in space, which is less than they sleep on Earth. Such short sleep duration has been associated with reduced alertness and performance in space. It is unclear whether this sleep loss is related to modifiable factors, such as irregular scheduling, poor sleep environment, and excessive workload or due to features of spaceflight that alter physiology (e.g., microgravity). Recent missions have afforded crew better, more stable sleep and work schedules, and an improved sleep environment. Despite these improvements, schedules do still vary enough to cause decrements in sleep duration. METHODS: Crewmembers (n = 19) who volunteered for the NASA Standard Measures protocol between January 2019 and March 2022 were provided with actiwatches (Phillips, Respironics, Bend OR) that they wore for two bouts of data collection lasting two weeks each before flight (at approximately L-270 and L-180), either continuously (n = 9) or for two weeks every two months while in space (n = 10), and for seven days postflight, immediately upon return to Earth (R+0). A regularly scheduled (or “nominal”) sleep episode would take place between the hours of 9:30pm and 6:00am. We looked at sleep outcomes (sleep duration, wake after sleep onset [WASO], sleep efficiency) depending on the distance from nominal sleep offset to see whether scheduled sleep period affected sleep durations and other metrics of sleep quality. RESULTS: Crewmembers provided data from 402 nights preflight, 2,137 nights inflight, and 275 nights postflight. They averaged 7.33 hours of sleep per night (± 1.16, SD) in space. Though this was significantly less sleep than they achieved preflight (7.87 ± 1.10) or postflight (7.75 ± 1.43, p < .01), this duration of sleep meets the recommended amount for optimal human health and well-being. For every hour after the nominal sleep period a crewmember woke up, their total sleep increased by 25 minutes (up to 5 hours). CONCLUSIONS: We conclude that humans are capable of achieving sufficient sleep in space, especially when their schedules afford adequate sleep (namely, schedules that phase delay rather than advance). Future studies are needed to determine whether microgravity impacts sleep architecture and sleep quality. Going forward, it is imperative that crewmembers are provided with stable schedules, with moderate workload, and environments that are conducive to sleep.
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Following a second crew report of excess water inexplicably accumulating in the helmet during EVA-80 on March 23, 2022, NASA initiated an aggressive effort to identify, mitigate, and/or eliminate all sources of the potentially life-threatening water. Our narration highlights demonstrations of microgravity flow expectations using terrestrial scale models, mitigations to dangerous water migration within the helmet, low-g two-phase flow separations for the flow entering the helmet, and an investigation of the nature of liquid carry-over from the EMU condensing heat exchanger source. Fast-to-flight demonstrations of each aspect of the work are carried out during hands-on crew interaction with flight scale hardware on ISS during the 2022-2023 timeframe. The results of the tests are described with a focus on the rarely observed, and thus rarely studied, large length scale air-driven wall-bound droplet and rivulet twophase flows in microgravity. The success of the mitigations and directions for continued work is discussed in summary.
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Following a second crew report of excess water inexplicably accumulating in the helmet during EVA-80 on March 23, 2022, NASA initiated an aggressive effort to identify, mitigate, and/or eliminate all sources of the potentially life-threatening water. Our narration highlights demonstrations of microgravity flow expectations using terrestrial scale models, mitigations to dangerous water migration within the helmet, low-g two-phase flow separations for the flow entering the helmet, and an investigation of the nature of liquid carry-over from the EMU condensing heat exchanger source. Fast-to-flight demonstrations of each aspect of the work are carried out during hands-on crew interaction with flight scale hardware on ISS during the 2022-2023 timeframe. The results of the tests are described with a focus on the rarely observed, and thus rarely studied, large length scale air-driven wall-bound droplet and rivulet twophase flows in microgravity. The success of the mitigations and directions for continued work is discussed in summary.
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Addressing the hazards and defining solutions will require a combination of human health and performance and engineering solutions. These solutions will be balanced with acceptable risks imposed on the crew and mission parameters such as duration, vehicle designs, operational considerations, and cost.
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As spaceflight continues to advance, understanding who has been to space in the past and what occurred during those missions, can help us better create a contextual foundation for the data that has been collected. This foundation can in turn guide how data may be generalized and applied to future crew selections and mission programs.
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