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At least 901 records · Page 50

The Martian sources of the SNC meteorites (two, not one), and what can and can't be learned from the SNC meteorites

The SNC meteorites, which almost certainly originate in the Martian crust, have been inferred to come from a single impact crater site, but no known crater fits all criteria. Formation at two separate sites (S from one, NC from the other) is more consistent with the sum of petrologic, geochronologic, and cosmochronologic data. If the source craters for the SNC meteorites can be located, Mars science will advance considerably. However, many significant questions cannot be answered by the SNC meteorites. These questions await a returned sample.

Treiman, A. H.↗

Science Rationale for Jupiter Entry Probe as Part of JIMO

A Jupiter atmospheric entry probe as part of JIMO is a cost effective way to address fundamental science questions identified in the National Research Council Solar System Exploration Decadal Survey (SSEDS): New Frontiers in the Solar System, An Integrated Ex- ploration Strategy. Compared to either the cost of an entirely separate Jupiter mission, or the cost of JIMO itself, inclusion of such a probe on JIMO would be cost advantageous. The probe itself could be relatively simple, and could build on the Galileo Probe heritage. The SSEDS specifically identified the distribution of water across the Solar System as a Key Scientific Question. Correspondingly, knowing the water abun dance on Jupiter is fundamental to understanding almost every aspect of the evolution of the early solar nebula. The Galileo Probe obtained the abundance of several key elements in Jupiter's atmosphere, which data have already caused major rethinking of theories of how Jupiter formed and how the early solar nebula evolved. However, because of a combination of circumstances, the global abundance of the key element oxygen, in the form of water, was not obtained. Without knowledge of the jovian water abundance, further progress in understanding Solar System evolution and planet formation will be greatly inhibited. Therefore, quantifying jovian water abundance should be a goal of the very next mission to the jovian system. Such a measurement would be impossible via remote sensing from the JIMO orbiter because of the large distances the JIMO orbiter maintains from Jupiter. A Jupiter atmospheric entry probe as part of JIMO could achieve the fundamental water measurement. In order that a probe avoid repeating the Galileo probe's experience of failing to obtain the jovian water abundance, the probe should go deep, to at least 100 bars pressure. Probes to 100 bars have been accomplished many times in descending to the surface of Venus, and at 100 bars the temperature of the jovian atmosphere is 60-70 K less than the surface temperature of Venus.

Young, R. E.↗

Precision Measurement of Black Hole Binary Dynamics: Analyzing the LISA Data Stream

One of the richest potential sources of insight into fundamental physics that LISA will be capable of observing is the inspiral of supermassive black hole binaries (BHBs). However, the data analysis challenge presented by the LISA data stream is quite unlike the situation for present day gravitational wave detectors. In order to make the precision measurements necessary to achieve LISA's science goals, the BHB signal must be distinguished from a data stream that not only contains instrumental noise, but potentially thousands of other signals as well, so that the "background" we wish to separate out to focus on the BHB signal is likely to be highly nonstationary and nongaussian, as well as being of scientific interest in its own right. In addition, whereas the theoretical templates that we calculate in order to ultimately estimate the parameters can afford to be somewhat inaccurate and still be effective for present day and near future detectors, this is not the case for LISA, and extremely high fidelity of the theoretical templates for high signal-to-noise signals will be required to prevent theoretical errors from dominating the parameter estimates. NVe, will describe efforts in the community of LISA data analysts to address the challenges regarding the specific issue of BHB signals. These efforts include using a Markov Chain Monte Carlo approach with the freedom to model the BHB and the other signals present in the data stream simultaneously, rather than trying to remove other signals and risk biasing the remaining data. The Mock LISA Data Challenge is a community of LISA scientists who generate rounds of simulated LISA noise with increasingly difficult signal content, and invite the LISA data analysis community to exercise their methods, or develop new methods, in an attempt to extract the parameters for the signals embedded in the mock data. In addition to practical approaches such ,is this to assess the level of parameter accuracy, one can apply the Fisher matrix formalism to assess both the statistical errors from noise and the theoretical errors

McWilliams, Sean T.↗

The Impact of Apollo-Era Microbiology on Human Space Flight

The microbiota of crewmembers and the spacecraft environment contributes significant risk to crew health during space flight missions. NASA reduces microbial risk with various mitigation methods that originated during the Apollo Program and continued to evolve through subsequent programs: Skylab, Shuttle, and International Space Station (ISS). A quarantine of the crew and lunar surface samples, within the Lunar Receiving Laboratory following return from the Moon, was used to prevent contamination with unknown extraterrestrial organisms. The quarantine durations for the crew and lunar samples were 21 days and 50 days, respectively. A series of infections among Apollo crewmembers resulted in a quarantine before launch to limit exposure to infectious organisms. This Health Stabilization Program isolated the crew for 21 days before flight and was effective in reducing crew illness. After the program developed water recovery hardware for Apollo spacecraft, the 1967 National Academy of Science Space Science Board recommended the monitoring of potable water. NASA implemented acceptability limits of 10 colony forming units (CFU) per mL and the absence of viable E. coli, anaerobes, yeasts, and molds in three separate 150 mL aliquots. Microbiological investigations of the crew and spacecraft environment were conducted during the Apollo program, including the Apollo-Soyuz Test Project and Skylab. Subsequent space programs implemented microbial screening of the crew for pathogens and acceptability limits on spacecraft surfaces and air. Microbiology risk mitigation methods have evolved since the Apollo program. NASA cancelled the quarantine of the crew after return from the lunar surface, reduced the duration of the Health Stabilization Program; and implemented acceptability limits for spacecraft surfaces and air. While microbial risks were not a main focus of the early Mercury and Gemini programs, the extended duration of Apollo flights resulted in the increased scrutiny of impact of the space flight environment on crew health. The lessons learned during that era of space flight continue to impact microbiology risk mitigation in space programs today.

Elliott, T. F↗

Lightweight inorganic membrane module

An apparatus and system for separating a liquid from a mixed gas stream includes a porous graphite foam support comprising graphite foam with pores having a first pore size and a membrane support surface. A porous condensation membrane layer is provided on the membrane support surface, and interlocked with the pores of the graphite foam. The condensation membrane layer includes capillary condensation pores having a second pore size that is less than the first pore size. A mixed gas stream passageway is in fluid communication with the condensation membrane layer. A liquid collection assembly collects condensed liquid from the condensation pores and the graphite foam support pores. A gas inlet is provided for flowing the mixed gas stream into the mixed gas stream passageway. A gas outlet is provided for exhausting gas from the mixed gas stream passageway. A method for separating a liquid from a mixed gas stream is also disclosed.

36 MATERIALS SCIENCE↗

Production of Renewable Solvents and Monomers from Lignocellulosic Feedstocks

Lignocellulosic biomass is pretreated and broken down into cellulosic sugars. The cellulosic sugars are converted to mevalonolactone (MVL) using Visolis’ proprietary microbes. The MVL containing broth is separated from the cells, deashed-decolorized, concentrated and fed into a catalytic reactor to develop anhydro mevalonolactone (aMVL), and 3-methyl pentanediol (3MPD). The products were separated by distillation into high purity compounds as solvent or polymer applications.

3-methyl pentanediol, polymer, solvent↗

Advances in 3D Geologic Modeling of Alluvial Basins with a Focus on Facies and Property Modeling

The unsaturated zone alluvium reference case is one of several geologic systems under consideration by the U.S. Department of Energy Office of Nuclear Energy for hosting repositories for spent nuclear fuel and associated waste (Sevougian et al., 2019). As noted by Mariner et al. (2018), the generic alluvial basin offers positive attributes that merit its consideration as a reference case by the Spent Fuel and Waste Science and Technology (SFWST) campaign. There are hundreds of alluvial basins and sub-basins scattered across the arid western United States (Figure 1-1). Precipitation and infiltration rates are relatively low with high evapotranspiration, resulting in vertical separation between repository and water table and thus longer transport paths to an aquifer. Accumulations of alluvial sediments within these basins are typically on the order of hundreds of meters, and locally may exceed 1,000 m in thickness, as is the case for the Deming sub-basin in southern New Mexico. A thick geologic host medium, which serves as the natural barrier system (NBS) in the conceptual model framework of a geologic disposal system, isolates the waste packages from receptors in the biosphere. Further, alluvial basin fill is typically comprised of stacked playa and lacustrine deposits along the basin axis (Perry et al., 2018). Characterized by low permeability, these layers protect the biosphere above the repository and the groundwater resources below the repository.

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

Mars Science Laboratory Orbit Determination

Mars Science Laboratory (MSL) Orbit Determination (OD) met all requirements with considerable margin, MSL OD team developed spin signature removal tool and successfully used the tool during cruise, A novel approach was used for the MSL solar radiation pressure model and resulted in a very accurate model during the approach phase, The change in velocity for Attitude Control System (ACS) turns was successfully calibrated and with appropriate scale factor resulted in improved change in velocity prediction for future turns, All Trajectory Correction Maneuvers were successfully reconstructed and execution errors were well below the assumed pre-fight execution errors, The official OD solutions were statistically consistent throughout cruise and for OD solutions with different arc lengths as well, Only EPU-1 was sent to MSL. All other Entry Parameter Updates were waived, EPU-1 solution was only 200 m separated from final trajectory reconstruction in the B-plane

Mars Science Laboratory (MSL)↗

Introduction to Air Traffic Management

The presentation introduces students and faculty to air traffic management with focus on air traffic data for data-science. Starting with the common attributes of transportation systems — highway transportation, air transportation and data transportation, the initial set of slides discuss the purpose of data-science in air traffic management, reasons why air traffic management is challenging, and the multidisciplinary nature of air traffic management research. The history of flight from 1903 — Wright Flyer — to 1987 — formation of the National Air Traffic Controllers Association — is briefly discussed. The national airspace system is described in terms of airports in the U. S., air traffic control facilities (flight service stations, terminal, enroute and system command center), airspace geometry (sectors, airways and navaids), governing regulations and directives, airspace classification (Class A through G), special use airspace, visual flight rules and instrument flight rules. The contents of a flight-plan are described. Weather briefing is discussed. The surveillance equipment used for surface, terminal area and enroute are described, and the aircraft states obtained using the surveillance data are listed. Airline operations control functions — schedule development, flight planning, resource scheduling and flight following — are noted. Next, the roles and responsibilities of air traffic controllers and traffic flow managers are discussed. Separation standards and conflict resolution techniques are outlined. Finally, traffic flow management techniques are reviewed with an illustrative example.

Air Traffic Management↗

The JWST Early-Release Science Program for Direct Observations of Exoplanetary Systems II: A 1 to 20 μM Spectrum of the Planetary-Mass Companion VHS 1256–1257 B

We present the highest fidelity spectrum to date of a planetary-mass object. VHS 1256 b is a <20 M Jup widely separated (∼8'', a = 150 au), young, planetary-mass companion that shares photometric colors and spectroscopic features with the directly imaged exoplanets HR 8799c, d, and e. As an L-to-T transition object, VHS 1256 b exists along the region of the color–magnitude diagram where substellar atmospheres transition from cloudy to clear. We observed VHS 1256 b with JWST's NIRSpec IFU and MIRI MRS modes for coverage from 1 to 20 μm at resolutions of ∼1000–3700. Water, methane, carbon monoxide, carbon dioxide, sodium, and potassium are observed in several portions of the JWST spectrum based on comparisons from template brown dwarf spectra, molecular opacities, and atmospheric models. The spectral shape of VHS 1256 b is influenced by disequilibrium chemistry and clouds. We directly detect silicate clouds, the first such detection reported for a planetary-mass companion.

Brown dwarfs↗

Adsorption processes in spacecraft environmental control and life support systems

The environmental control and life support system on a spacecraft maintains a safe and comfortable environment in which the crew can live and work by supplying oxygen and water and by removing carbon dioxide, water vapor, and trace contaminants from cabin air. Although open-loop systems have been used successfully in the past for short-duration missions, the economics of current and future long-duration missions in space will make nearly complete recycling of air and water imperative. A variety of operations will be necessary to achieve the goal of nearly complete recycling. These include separation and reduction of carbon dioxide, removal of trace gas-phase contaminants, recovery and purification of humidity condensate, purification and polishing of wastewater streams, and others. Several of these can be performed totally or in part by adsorption processes. These processes are good candidates to perform separations and purifications in space due to their gravity independence, high reliability, relative high energy efficiency, design flexibility, technological maturity, and regenerative nature. For these reasons, adsorption has historically played a key role in life support on U.S. and Russian piloted spacecraft. Among the life support applications that can be achieved through use of adsorption technology are removal of trace contaminants and carbon dioxide from cabin air and recovery of potable water from waste streams. In each of these cases adsorption technology has been selected for use onboard the International Space Station. The requirements, science, and hardware for these applications are discussed. Human space exploration may eventually lead to construction of planetary habitats. These habitats may provide additional opportunities for use of adsorption processes, such as control of greenhouse gas composition, and may have different resources available to them, such as gases present in the planetary atmosphere. Separation and purification processes based on adsorption can be expected to continue to fulfill environmental control and life support needs on future missions.

Review, Tutorial↗

Multiscale simulations reveal TDP-43 molecular-level interactions driving condensation

The RNA-binding protein TDP-43 is associated with mRNA processing and transport from the nucleus to the cytoplasm. TDP-43 localizes in the nucleus as well as accumulating in cytoplasmic condensates such as stress granules. Aggregation and formation of amyloid-like fibrils of cytoplasmic TDP-43 are hallmarks of numerous neurodegenerative diseases, most strikingly present in >90% of amyotrophic lateral sclerosis (ALS) patients. If excessive accumulation of cytoplasmic TDP-43 causes, or is caused by, neurodegeneration is presently not known. In this work, we use molecular dynamics simulations at multiple resolutions to explore TDP-43 self- and cross-interaction dynamics. A full-length molecular model of TDP-43, all 414 amino acids, was constructed from select structures of the protein functional domains (N-terminal domain, and two RNA recognition motifs, RRM1 and RRM2) and modeling of disordered connecting loops and the low complexity glycine-rich C-terminus domain. All-atom CHARMM36m simulations of single TDP-43 proteins served as guides to construct a coarse-grained Martini 3 model of TDP-43. The Martini model and a coarser implicit solvent Cα model, optimized for disordered proteins, were subsequently used to probe TDP-43 interactions; self-interactions from single-chain full-length TDP-43 simulations, cross-interactions from simulations with two proteins and simulations with assemblies of dozens to hundreds of proteins. Our findings illustrate the utility of different modeling scales for accessing TDP-43 molecular-level interactions and suggest that TDP-43 has numerous interaction preferences or patterns, exhibiting an overall strong, but dynamic, association and driving the formation of biomolecular condensates.

59 BASIC BIOLOGICAL SCIENCES↗

In Silico Discovery of Covalent Organic Frameworks for Carbon Capture

We screen a database of more than 69 000 hypothetical covalent organic frameworks (COFs) for carbon capture using parasitic energy as a metric. To compute CO 2 –framework interactions in molecular simulations, we develop a genetic algorithm to tune the charge equilibration method and derive accurate framework partial charges. Nearly 400 COFs are identified with parasitic energy lower than that of an amine scrubbing process using monoethanolamine; more than 70 are better performers than the best experimental COFs and several perform similarly to Mg-MOF-74. We analyze the effect of pore topology on carbon capture performance to guide the development of improved carbon capture materials.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Expeditious synthesis of covalent organic frameworks: a review

Covalent organic frameworks (COFs), a burgeoning class of crystalline porous materials constructed by covalently connecting organic building blocks, have garnered tremendous attention. The predominant solvothermal synthesis of COFs usually requires high temperature and long reaction times (three days or longer), which creates substantial obstacles for their accelerated discovery and exploration in practical applications. Hence, the expeditious synthesis of COFs without compromising their inherent properties is exceedingly appealing from the viewpoint of cost, time, and energy footprint. To overcome the sluggishness of the synthesis, considerable efforts have been invested in the rapid synthesis of high-quality COFs through innovations in energy source, catalyst, solvent, monomer, nucleation, and workup activation, leading to a drastic reduction of reaction time from multiple days to a few hours, and even to seconds in some cases. In this contribution, we provide a comprehensive overview of the advances in expediting the synthesis science of COFs. Though a nascent effort, six prevalent strategies have been identified for the rapid synthesis of COFs, which have led to intriguing applications in a diverse range of areas including gas adsorption, separation, heterogeneous catalysis, environmental remediation, and photodynamic therapy. We also outline the major challenges and perspectives on the future directions empowered by expeditious COF synthesis.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗