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At least 901 records · Page 50
All sourcesNASA NTRSDOE OSTI
NASA NTRS1997

Immune alterations in male and female mice after 2-deoxy-D-glucose administration

Administration of 2-deoxy-D-glucose (2-DG) induces acute cellular glucoprivation. In the current study, we examined differences in immune parameters after 2-DG administration in both sexes. Male and female BDF1 mice were injected three times, 48 h apart, either with a saline solution (control group) or with 2-DG in saline (500 mg/kg). Two hours after the last injection, blood and spleens were collected. Plasma levels of interleukin-1beta, and interferon-gamma levels were measured. Additionally, the levels of the specific leukocyte antigens CD3, CD4, CD8, T cell receptor (TCR) alpha/beta, I-Ad, and H-2Ld/H-2Db were evaluated by flow cytometry on both blood and spleen cells. The blastogenic response of leukocytes from both tissues to mitogens was assessed. Levels of glucose, corticosterone, testosterone, progesterone, 17beta-estradiol, follicle-stimulating hormone, and luteinizing hormone were also determined. Increases in the percentage of cells bearing TCR alpha/beta and I-Ad in the blood and H-2Ld/H-2Db in the spleen were observed in the 2-DG-treated group for both sexes. In contrast, higher corticosterone and IL-1beta plasma concentrations, as well as higher percentages of splenocytes bearing TCR alpha/beta and I-Ad, and lower mitogen-induced proliferation of mature T splenocytes (79%) were observed in female but not in male mice injected with 2-DG compared with those injected with saline (p < 0.05). Taken together, these results suggest that female mice are more sensitive than male mice to immune alterations induced by 2-DG administration.

Non-NASA Center↗
NASA NTRS2010

Miniature Low-Mass Drill Actuated by Flextensional Piezo Stack

Recent experiments with a flextensional piezoelectric actuator have led to the development of a sampler with a bit that is designed to produce and capture a full set of sample forms including volatiles, powdered cuttings, and core fragments. The flextensional piezoelectric actuator is a part of a series of devices used to amplify the generated strain from piezoelectric actuators. Other examples include stacks, bimorphs, benders, and cantilevers. These devices combine geometric and resonance amplifications to produce large stroke at high power density. The operation of this sampler/drill was demonstrated using a 3x2x1-cm actuator weighing 12 g using power of about 10-W and a preload of about 10 N. A limestone block was drilled to a depth of about 1 cm in five minutes to produce powdered cuttings. It is generally hard to collect volatiles from random surface profiles found in rocks and sediment, powdered cuttings, and core fragments. Toward the end of collecting volatiles, the actuator and the bit are covered with bellows-shaped shrouds to prevent fines and other debris from reaching the analyzer. A tube with a miniature bellows (to provide flexibility) is connected to the bit and directs the flow of the volatiles to the analyzer. Another modality was conceived where the hose is connected to the bellows wall directly to allow the capture of volatiles generated both inside and outside the bit. A wide variety of commercial bellows used in the vacuum and microwave industries can be used to design the volatiles capture mechanism. The piezoelectric drilling mechanism can potentially be operated in a broad temperature range from about-200 to less than 450 C. The actuators used here are similar to the actuators that are currently baselined to fly as part of the inlet funnel shaking mechanism design of MSL (Mars Science Laboratory). The space qualification of these parts gives this drill a higher potential for inclusion in a future mission, especially when considering its characteristics of low mass, small size, low power, and low axial loads for sampling.

Sherrit, Stewart↗
NASA NTRS2010

Incorporating Vibration Test Results for the Advanced Stirling Convertor into the System Dynamic Model

The U.S. Department of Energy (DOE), Lockheed Martin Corporation (LM), and NASA Glenn Research Center (GRC) have been developing the Advanced Stirling Radioisotope Generator (ASRG) for use as a power system for space science missions. As part of the extended operation testing of this power system, the Advanced Stirling Convertors (ASC) at NASA GRC undergo a vibration test sequence intended to simulate the vibration history that an ASC would experience when used in an ASRG for a space mission. During these tests, a data system collects several performance-related parameters from the convertor under test for health monitoring and analysis. Recently, an additional sensor recorded the slip table position during vibration testing to qualification level. The System Dynamic Model (SDM) integrates Stirling cycle thermodynamics, heat flow, mechanical mass, spring, damper systems, and electrical characteristics of the linear alternator and controller. This Paper presents a comparison of the performance of the ASC when exposed to vibration to that predicted by the SDM when exposed to the same vibration.

Meer, David W.↗
NASA NTRS2012

An Electrostatic Precipitator System for the Martian Environment

Human exploration missions to Mars will require the development of technologies for the utilization of the planet's own resources for the production of commodities. However, the Martian atmosphere contains large amounts of dust. The extraction of commodities from this atmosphere requires prior removal of this dust. We report on our development of an electrostatic precipitator able to collect Martian simulated dust particles in atmospheric conditions approaching those of Mars. Extensive experiments with an initial prototype in a simulated Martian atmosphere showed efficiencies of 99%. The design of a second prototype with aerosolized Martian simulated dust in a flow-through is described. Keywords: Space applications, electrostatic precipitator, particle control, particle charging

Calle, C. I.↗
NASA NTRS2014

The 1500m South Pole Ice Core: Recovering a 40 Ka Environmental Record

Supported by the US National Science Foundation, a new 1500 m, approximately 40 ka old ice core will be recovered from South Pole during the 2014/15 and 2015/16 austral summer seasons using the new US Intermediate Depth Drill. The combination of low temperatures, relatively high accumulation rates and low impurity concentrations at South Pole will yield detailed records of ice chemistry and trace atmospheric gases. The South Pole ice core will provide a climate history record of a unique area of the East Antarctic plateau that is partly influenced by weather systems that cross the West Antarctic ice sheet. The ice at South Pole flows at approximately 10m a(exp-1) and the South Pole ice-core site is a significant distance from an ice divide. Therefore, ice recovered at depth originated progressively farther upstream of the coring site. New ground-penetrating radar collected over the drill site location shows no anthropogenic influence over the past approximately 50 years or upper 15 m. Depth-age scale modeling results show consistent and plausible annual-layer thicknesses and accumulation rate histories, indicating that no significant stratigraphic disturbances exist in the upper 1500m near the ice-core drill site.

South Pole↗
NASA NTRS2014

Space Shuttle Boundary Layer Transition Flight Experiment Ground Testing Overview

In support of the Boundary Layer Transition (BLT) Flight Experiment (FE) Project in which a manufactured protuberance tile was installed on the port wing of Space Shuttle Orbiter Discovery for STS-119, STS- 128, STS-131 and STS-133 as well as Space Shuttle Orbiter Endeavour for STS-134, a significant ground test campaign was completed. The primary goals of the test campaign were to provide ground test data to support the planning and safety certification efforts required to fly the flight experiment as well as validation for the collected flight data. These test included Arcjet testing of the tile protuberance, aerothermal testing to determine the boundary layer transition behavior and resultant surface heating and planar laser induced fluorescence (PLIF) testing in order to gain a better understanding of the flow field characteristics associated with the flight experiment. This paper provides an overview of the BLT FE Project ground testing. High-level overviews of the facilities, models, test techniques and data are presented, along with a summary of the insights gained from each test.

Karen T Berger↗
NASA NTRS2014

TPSAS-NF1676L-19423-DND

In support of the Boundary Layer Transition (BLT) Flight Experiment (FE) Project in which a manufactured protuberance tile was installed on the port wing of Space Shuttle Orbiter Discovery for STS-119, STS-128, STS-131 and STS-133 as well as Space Shuttle Endeavour for STS-134, a significant wind tunnel test campaign was completed. The primary goals of the test campaign were to provide ground test data to support the planning and safety certification efforts required to fly the flight experiment as well as validation for the collected flight data. These test included Arcjet testing of the tile protuberance, aerothermal testing to determine the boundary layer transition behavior and resultant surface heating and planar laser induced fluorescence (PLIF) testing in order to gain a better understanding of the flow field characteristics of the flight experiment. This paper provides an overview of the BLT FE Project ground testing. High-level overviews of the facilities, models, test techniques and data are presented, along with a summary of the insights gained from each test.

Karen T Berger↗
NASA NTRS2021

Predicting near-saturated hydraulic conductivity in urban soils

Pedotransfer functions (PTFs) provide point predictions of soil hydraulic properties from more readily measured soil characteristics, yet uncertainties and biases in measurement methods, sampling distributions, and boundary conditions can limit accuracy when estimating near-saturated hydraulic conductivity (K(n)). These limitations may be particularly problematic in understudied urban landscapes that often contain altered hydraulic properties. To better treat deficiencies in PTF performance, we addressed three objectives, which were to: 1) develop PTFs to predict urban K(n), 2) assess bulk density and coarse fragments as explanatory variables; and 3) evaluate the predictive capability of these PTFs by comparing their output to measured hydraulic conductivity values from three other studies of urban soil hydraulics. We used artificial neural networks (ANN) and random forest (RF) approaches to predict urban K(n), with the training dataset including 307 tension infiltrometer tests and other measurements drawn from urban soil assessments in 11 U.S. cities. The PTFs utilized a hierarchy of inputs, starting with percentage sand, silt, clay, and then adding percentage coarse fragments and bulk density. The ANN models performed similar to the RF models, and all models exhibited similar or better predictive performance as models results collected from published articles. The inclusion of bulk density or coarse fragments did not improve accuracy over soil texture alone. Possible reasons for this result include low correlation between K(n) and bulk density and the exclusion of large voids during flow measurements with tension infiltrometers. The models have been made available as an open-source software package to encourage adoption by users working in urban systems.

Jinshi Jian↗
NASA NTRSDate not supplied

Initial Validation of a Gas-Granular Flow Solver Using a Subscale, Reduced Pressure Plume Surface Interaction Ground Test

With NASA’s goal to land the next humans on the lunar surface in the next few years, it is vitally important to have a better understanding of the plume surface interaction (PSI) between the landing vehicles and the lunar regolith. The Fluid Dynamics Branch at NASA/MSFC has previously used the gas-granular flow solver Loci/GGFS to qualitatively predict crater formation due to PSI effects in a lunar (near vacuum) ambient environment. In this paper, validation of Loci/GGFS crater width and depth predictions in ambient near-lunar conditions are provided using experimental data collected at MSFC during the Physics-Focused Ground Test 1 (PFGT-1) campaign in 2022. To observe sensitivity to soil models, simulations were conducted with both monodisperse glass bead (MGB) and BP-1 lunar regolith simulant soil models in Loci/GGFS. Crater depth and width comparisons are made with PFGT-1 Run 56, which used BP-1 soil. The Loci/GGFS BP-1 soil model performed slightly better with a mean predicted crater depth within 10% of the experiment. Both soil models predicted crater width within 10%. Cratering occurred more quickly with the MGB soil model. Mesh and spatial order sensitivity are also examined for the BP-1 soil model.

Validation↗
NASA NTRSDate not supplied

Atmospheric, Non-Combusting Droplet Sizing and Spray Imaging Results From a Non-Proprietary Aero Gas Turbine Engine Pressure Swirl Atomizer using Shadowgraphy and Planar Laser Scatter

Members from industry and federal agencies of the United States have developed a collaborating group focused on improving the understanding of the atomization processes common to gas turbine engines. The group is aimed on providing high quality data using x-ray diagnostics in the internal geometry and the near-field dense spray as well as optical diagnostics in the visible spectrum, downstream of the nozzle. This paper reports results from one of the two non-proprietary injectors designs from the group: the primary-secondary injector. In particular, we characterize the spray from only the primary, pressure-swirl atomizing circuit using water through the nozzle. We observed Sauter mean diameter decreased with increased water pressure drop across the nozzle. SMD was also collected at three axial distances and showed decreased size with distance from the nozzle. Planar laser sheet droplet scattering provided qualitative assessment of the spray. Higher water pressure drops provided better atomization than lower pressure drops. The addition of swirling air flow through the injector alleviates and improves the atomization quality, particularly at the lower water pressure drops.

optical diagnostics↗
NASA NTRS1973

Applications of ERTS-1 Data Collection System (DCS) in the Arizona Regional Ecological Test Site (ARETS)

The author has identified the following significant results. The DCS water-stage data from the USGS streamflow gaging station on the Verde River near Camp Verde furnished information sufficient for the accurate computation of daily mean streamflow rates during the first 2 months of operation. Daily mean flow rates computed from the DCS data agreed with those computed from the digital recorder data within + or - 5% during periods of stable or slowly changing flow and within + or - 10% during periods of rapidly changing high flow. The SRP was furnished near-real time DCS information on snow moisture content and streamflow rates for use in the management and operation of the multiple-use reservoir system. The SRP, by prudent water management and the use of near-real time hydrologic data furnished by microwave and ERTS DCS telemetry, was successful in anticipating the amount of flow into the Salt and Verde Rivers and in the subsequent release of water at rates that did not create flooding in metropolitan Phoenix. Only minor flooding occurred along the Gila River west of Phoenix. According to the Maricopa County Civil Defense agency, wage and salary losses of about $11,400,000 resulted from closing of roads across the Salt River in the winter and spring of 1972-73; however, the number and duration of the closing were minimized by use of DCS data.

Schumann, H. H.↗
NASA NTRS1994

In situ detection of tropospheric OH and HO2 by laser-induced fluorescence in a detection chamber at low pressure

Just as in the method of Hard and O'Brien, ambient air is pulled through an approximately 1 mm diameter inlet into a detection chamber that is maintained at a pressure of 2.4 torr. The ambient air stream travels through the detection chamber with a velocity of greater than 100 m sec(exp -1) in a narrow stream, constrained by the addition of an inert gas flow (0.4 torr). The OH molecule is both excited and detected in the A(exp 2)Sigma (v' = 0) yields X(exp 2)II (v'' = 0) transition at 308 nm. Light from a copper vapor-pumped dye laser (rep. rate = 10kHz; pulse length = 20 ns; linewidth = .1 cm(exp -1), and average power = 15 mW), resonant with the Q(sub 1)(3) transition, is multipassed through a White cell and intercepts the air stream as 24 non-overlapping 2mm by 5mm beams. A fast microchannel plate detector is turned off during the laser pulse to prevent saturation of the detector due to Rayleigh and chamber scattering. It is turned on 30-100 nsec after the end of the laser pulse for 300 ns to collect resonance fluorescence from OH. HO2 is detected by chemical conversion to OH by reaction with reagent NO, followed by OH detection. Both the detection sensitivity and the inlet characteristics must be understood for any in situ instrument. For the calibration of the detection sensitivity, OH is produced quantitatively by the fast H + NO2 yields OH + NO reaction in a low pressure, flowing discharge tube connected to the detection chamber. The inlet transmission of OH inlet is calibrated separately.

Brune, William H.↗
NASA NTRS2004

Validation and Analysis of SRTM and VCL Data Over Tropical Volcanoes

The focus of our investigation was on the application of digital topographic data in conducting first-order volcanological and structural studies of tropical volcanoes, focusing on the Java, the Philippines and the Galapagos Islands. Kilauea volcano, Hawaii, served as our test site for SRTM data validation. Volcanoes in humid tropical environments are frequently cloud covered, typically densely vegetated and erode rapidly, so that it was expected that new insights into the styles of eruption of these volcanoes could be obtained from analysis of topographic data. For instance, in certain parts of the world, such as Indonesia, even the regional structural context of volcanic centers is poorly known, and the distribution of volcanic products (e.g., lava flows, pyroclastic flows, and lahars) are not well mapped. SRTM and Vegetation Canopy Lidar (VCL) data were expected to provide new information on these volcanoes. Due to the cancellation of the VCL mission, we did not conduct any lidar studies during the duration of this project. Digital elevation models (DEMs) such as those collected by SRTM provide quantitative information about the time-integrated typical activity on a volcano and allow an assessment of the spatial and temporal contributions of various constructional and destructional processes to each volcano's present morphology. For basaltic volcanoes, P_c?w!m-d and Garbed (2000) have shown that gradual slopes (less than 5 deg.) occur where lava and tephra pond within calderas or in the saddles between adjacent volcanoes, as well as where lava deltas coalesce to form coastal plains. Vent concentration zones (axes of rift zones) have slopes ranging from 10 deg. to 12 deg. Differential vertical growth rates between vent concentration zones and adjacent mostly-lava flanks produce steep constructional slopes up to 40". The steepest slopes (locally approaching 90 deg.) are produced by fluvial erosion, caldera collapse, faulting, and catastrophic avalanches, all of which are usually identifiable. Due to the delay in the release of the SRTM data following the February 2000 flight, a significant part of our effort was devoted to the analog studies of the SRTM topographic data using topographic data from airborne interferometric radars. As part of the original SRTM Science Team, we proposed four study sites (Kilauea, Hawaii; Mt. Pinatubo, Philippines; Cerro Am1 and Femandina volcanoes, Galapagos Islands; and Tengger caldera, Java) where we could conduct detailed geologic studies to evaluate the uses of SRTM data for the analysis of lava flows, lahars, erosion of ash deposits, and an evaluation of the structural setting of the volcanoes. Only near the end of this project was one of these SRTM Science Team products (Luzon Island, the Philippines) released to the community, and we only had limited time to work on these data.

Mouginis-Mark, Peter J.↗
NASA NTRS1958

Correlations Among Ice Measurements, Impingement Rates Icing Conditions, and Drag Coefficients for Unswept NACA 65A004 Airfoil

An empirical relation has been obtained by which the change in drag coefficient caused by ice formations on an unswept NACA 65AO04 airfoil section can be determined from the following icing and operating conditions: icing time, airspeed, air total temperature, liquid-water content, cloud droplet impingement efficiencies, airfoil chord length, and angles of attack. The correlation was obtained by use of measured ice heights and ice angles. These measurements were obtained from a variety of ice formations, which were carefully photographed, cross-sectioned, and weighed. Ice weights increased at a constant rate with icing time in a rime icing condition and at progressively increasing rates in glaze icing conditions. Initial rates of ice collection agreed reasonably well with values predicted from droplet impingement data. Experimental droplet impingement rates obtained on this airfoil section agreed with previous theoretical calculations for angles of attack of 40 or less. Disagreement at higher angles of attack was attributed to flow separation from the upper surface of the experimental airfoil model.

Gray, Vernon H.↗
NASA NTRS1981

Determining solutions of hyperbolic systems from incomplete data

An investigation is conducted regarding first-order hyperbolic systems of partial differential equations, taking into account problems for which complete initial data are not available. Problems of the considered kind arise in geophysical applications where satellites are used to collect data. In global weather prediction, it is possible to derive atmospheric temperature and pressure reasonably well over the whole globe from satellite measurements; obtaining the wind field globally is more difficult. It is pointed out that a simple model of atmospheric flow investigated in numerical weather prediction is governed by the shallow water equations. The effect of the Coriolis term on the linearized shallow-water equations is studied.

Bube, K. P.↗
NASA NTRS1995

Instantaneous 2D Velocity and Temperature Measurements in High Speed Flows Based on Spectrally Resolved Molecular Rayleigh Scattering

A Rayleigh scattering diagnostic for high speed flows is described for the simultaneous, instantaneous measurement of gas temperature and velocity at a number (up to about one hundred) of locations in a plane illuminated by an injection-seeded, frequency doubled Nd:YAG laser. Molecular Rayleigh scattered light is collected and passed through a planar mirror Fabry-Perot interferometer. The resulting image is analyzed to determine the gas temperature and bulk velocity at each of the regions. The Cramer Rao lower bound for measurement uncertainty is calculated. Experimental data is presented for a free jet and for preliminary measurements in the Lewis 4 inch by 10 inch supersonic wind tunnel.

Seasholtz, Richard G.↗
NASA NTRS2002

Changes in Neutrophil Functions in Astronauts

Neutrophil functions (phagocytosis, oxidative burst, degranulation) and expression of surface markers involved in these functions were studied in 25 astronauts before and after 4 space shuttle missions. Space flight duration ranged from 5 to 11 days. Blood specimens were obtained 10 days before launch (preflight or L-10), immediately after landing (landing or R+0), and again at 3 days after landing (postflight or R+3). Blood samples were also collected from 9 healthy low-stressed subjects at 3 time points simulating a 10-day shuttle mission. The number of neutrophils increased at landing by 85 percent when compared to the preflight numbers. Neutrophil functions were studied in whole blood using flow cytometric methods. Phagocytosis of E.coli-FITC and oxidative burst capacity of the neutrophils following the 9 to 11 day missions were lower at all three sampling points than the mean values for control subjects. Phagocytosis and oxidative burst capacity of the astronauts was decreased even 10-days before space flight. Mission duration appears to be a factor in phagocytic and oxidative functions. In contrast, following the short-duration (5-days) mission, these functions were unchanged from control values. No consistent changes in degranulation were observed following either short or medium length space missions. The expression of CD16, CD32, CD11a, CD11b, CD11c, L-selectin and CD36 was measured and found to be variable. Specifically, CD16 and CD32 did not correlate with the changes in oxidative burst and phagocytosis. We can conclude from this study that the stresses associated with space flight can alter the important functions of neutrophils.

Kaur, Indreshpal↗
NASA NTRS2016

Extraction and Capture of Water from Martian Regolith Experimental Proof-of-Concept

A novel concept for extraction of water from the Mars soil in a real-time, open-air process was demonstrated in a Mars environment chamber. The concept breadboard uses radiative heating to bake off water from exposed soil contained in a bin. An enclosure, intended to mimic the bottom of a rover, covers the bin. A fan continuously blows the Mars atmospheric gases through the enclosure to collect the evolved water while a tiller was used to churn up moist subsurface soil. These initial tests verified concept feasibility. The sweep gas generated by commercially available muffin fans at 7 Torr was sufficient to transfer water vapor into a condenser flow loop. The radiative heating, while non-optimized, heated the soil surface to 60 C to generate water vapor. A rototiller working through the soil bin brought sufficient amounts of new moist soil to the heated surface to show an increase in rate of water extraction.

Mars Exploration↗