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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 91 records · Page 5
All sourcesNASA NTRSDOE OSTI
DOE OSTI2018

Non-catalytic signaling by pseudokinase ILK for regulating cell adhesion

Dynamic communication between integrin-containing complexes (focal adhesions, FAs) and actin filaments is critical for regulating cell adhesion. Pseudokinase ILK plays a key role in this process but the underlying mechanism remains highly elusive. Here in this paper we show that by recruiting FA adaptors PINCH and Parvin into a heterotrimeric complex (IPP), ILK triggers F-actin filament bundling – a process known to generate force/mechanical signal to promote cytoskeleton reassembly and dynamic cell adhesion. Structural, biochemical, and functional analyses revealed that the F-actin bundling is orchestrated by two previously unrecognized WASP-Homology-2 actin binding motifs within IPP, one from PINCH and the other from Parvin. Strikingly, this process is also sensitized to Mg-ATP bound to the pseudoactive site of ILK and its dysregulation severely impairs stress fibers formation, cell spreading, and migration. These data identify a crucial mechanism for ILK, highlighting its uniqueness as a pseudokinase to transduce non-catalytic signal and regulate cell adhesion.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗
DOE OSTI2024

Increased accuracy and signal-to-noise ratio through recent improvements in infra-red video bolometer fabrication and calibration

The infra-red video bolometer (IRVB) is a diagnostic equipped with an infra-red camera that measures the total radiated power in thousands of lines of sight within a large field of view. Recently validated in MAST-U [Fderici et al., Rev. Sci. Instrum. 94, 033502 (2023)], it offers a high spatial resolution map of the radiated power in the divertor region, where large gradients are expected. The IRVB’s sensing element comprises a thin layer of high Z absorbing material, typically platinum, usually coated with carbon to reduce reflections [Peterson et al., Rev. Sci. Instrum. 79, 10E301 (2008)].Here, the possibility of using a relatively inert material such as titanium, is explored that can be produced in layers up to 1 μm compared to 2.5 μm for Pt and then coat it with Pt of the desired thickness (0.3 μm per side here) and carbon. This leads to a higher temperature signal (about 3 times) and better spatial resolution (about 4 times), resulting in higher accuracy in the measured power [Peterson et al., Rev. Sci. Instrum. 79, 10E301 (2008)]. This assembly is also expected to improve foil uniformity, as the Pt layer is obtained via deposition rather than mechanical processes [Mukai et al., Rev. Sci. Instrum. 87, 2014 (2016)].Given its multi-material composition, measuring the thermal properties of the foil assembly is vital. Various methods using a calibrated laser as a heat source have been developed, analyzing the temperature profile shape [Sano et al., Plasma and Fusion Res. 7, 2405039 (2012)] and [Mukai et al., Rev. Sci. Instrum. 89, 10E114 (2018)] or fitting the calculated laser power for different intensities and frequencies [Fderici et al., Rev. Sci. Instrum. 94, 033502 (2023)]. Here, a simpler approach is presented, which relies on analyzing the separate components of the foil heat equation for a single laser exposure in a given area. This can then be iterated over the entire foil to capture local deviations.

Magnetic Fusion Energy↗
DOE OSTI2017

Liquid argon TPC signal formation, signal processing and reconstruction techniques

This document describes a reconstruction chain that was developed for the ArgoNeuT and MicroBooNE experiments at Fermilab. These experiments study accelerator neutrino interactions that occur in a Liquid Argon Time Projection Chamber. Reconstructing the properties of particles produced in these interactions benefits from the knowledge of the micro-physics processes that affect the creation and transport of ionization electrons to the readout system. A wire signal deconvolution technique was developed to convert wire signals to a standard form for hit reconstruction, to remove artifacts in the electronics chain and to remove coherent noise. A unique clustering algorithm reconstructs line-like trajectories and vertices in two dimensions which are then matched to create of 3D objects. In conclusion, these techniques and algorithms are available to all experiments that use the LArSoft suite of software.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗
DOE OSTI2022

Identification of Intraday False Data Injection Attack on DER Dispatch Signals

The urgent need for the decarbonization of power grids has accelerated the integration of renewable energy. Concurrently, increasing distributed energy resources (DER) and advanced metering infrastructure (AMI) have transformed the power grids into a more sophisticated cyber-physical system with numerous communication devices. While these transitions provide economic and environmental value, they also impose increased risk of cyber attacks and operation al challenges. This paper investigates the vulnerabilit y of the power grids with high renewable penetration against an intraday false data injection (FDI) attack on DER dispatch signals and proposes a kernel support vector regression (SVR) based detection model as a countermeasure. The intraday FDI attack scenario and the detection model are demonstrated in a numerical experiment using the HCE 187-bus test system.

Kim, Jip↗
DOE OSTI2023

Final amplifier of an ultra-intense all-OPCPA system with 13-J output signal energy and 41% pump-to-signal conversion efficiency

Optical parametric chirped-pulse amplification (OPCPA) using high-energy Nd:glass lasers has the potential to produce ultra-intense pulses (>10 23 W/cm 2 ). We report on the performance of the final high-efficiency amplifier in an OPCPA system based on large-aperture (63 × 63-mm 2 ) partially deuterated potassium dihydrogen phosphate (DKDP) crystals. The seed beam (180-nm bandwidth, 110 mJ) was provided by the preceding OPCPA stages. A maximum pump-to-signal conversion efficiency of 41% and signal energy up to 13 J were achieved with a 52-mm-long DKDP crystal due to the flattop super-Gaussian pump beam profile and flat-in-time pulse shape.

47 OTHER INSTRUMENTATION↗
DOE OSTI2023

Improving Signal-to-Noise Ratio (SNR) for Quantum Readout Signals Using Adaptive Hardware Filters on FPGA

This research presents an innovative approach to improving the Signal-to-Noise Ratio (SNR) in superconducting quantum computing readout signals, utilizing FPGA-based adaptive filtering on the control board. Our solution aims to bolster quantum computations' reliability by providing a more accurate and precise way to obtain our readout traces and achieve a higher discernability between excitation states in real-time.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗
NASA NTRS1973

The application of the analog signal to discrete time interval converter to the signal conditioner power supplies

The Analog Signal to Discrete Time Interval Converter microminiaturized module was utilized to control the signal conditioner power supplies. The multi-loop control provides outstanding static and dynamic performance characteristics, exceeding those generally associated with single-loop regulators. Eight converter boards, each containing three independent dc to dc converter, were built, tested, and delivered.

Schoenfeld, A. D.↗
NASA NTRS1986

A user's guide for the signal processing software for image and speech compression developed in the Communications and Signal Processing Laboratory (CSPL), version 1

A complete documentation of the software developed in the Communication and Signal Processing Laboratory (CSPL) during the period of July 1985 to March 1986 is provided. Utility programs and subroutines that were developed for a user-friendly image and speech processing environment are described. Additional programs for data compression of image and speech type signals are included. Also, programs for the zero-memory and block transform quantization in the presence of channel noise are described. Finally, several routines for simulating the perfromance of image compression algorithms are included.

Kumar, P.↗