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At least 91 records · Page 5

Different mechanisms of radiation-induced loss of heterozygosity in two human lymphoid cell lines from a single donor

Allelic loss is an important mutational mechanism in human carcinogenesis. Loss of heterozygosity (LOH) at an autosomal locus is one outcome of the repair of DNA double-strand breaks (DSBs) and can occur by deletion or by mitotic recombination. We report that mitotic recombination between homologous chromosomes occurred in human lymphoid cells exposed to densely ionizing radiation. We used cells derived from the same donor that express either normal TP53 (TK6 cells) or homozygous mutant TP53 (WTK1 cells) to assess the influence of TP53 on radiation-induced mutagenesis. Expression of mutant TP53 (Met 237 Ile) was associated with a small increase in mutation frequencies at the hemizygous HPRT (hypoxanthine phosphoribosyl transferase) locus, but the mutation spectra were unaffected at this locus. In contrast, WTK1 cells (mutant TP53) were 30-fold more susceptible than TK6 cells (wild-type TP53) to radiation-induced mutagenesis at the TK1 (thymidine kinase) locus. Gene dosage analysis combined with microsatellite marker analysis showed that the increase in TK1 mutagenesis in WTK1 cells could be attributed, in part, to mitotic recombination. The microsatellite marker analysis over a 64-cM region on chromosome 17q indicated that the recombinational events could initiate at different positions between the TK1 locus and the centromere. Virtually all of the recombinational LOH events extended beyond the TK1 locus to the most telomeric marker. In general, longer LOH tracts were observed in mutants from WTK1 cells than in mutants from TK6 cells. Taken together, the results demonstrate that the incidence of radi-ation-induced mutations is dependent on the genetic background of the cell at risk, on the locus examined, and on the mechanisms for mutation available at the locus of interest.

NASA Discipline Radiation Health↗

Identification of Brillouin Zones by In-Plane Lasing from Light-Cone Surface Lattice Resonances

Periodic optical structures can control the flow of light, which has facilitated applications in optical fibers, laser cavities, and biochemical sensors. The first Brillouin zone (BZ) in reciprocal space can describe all the electromagnetic fields localized inside a photonic lattice. However, photonic lattices also exhibit radiative losses from light scattering, but the radiated fields are not captured by the first BZ. In a two-dimensional lattice, the in-plane wavevectors of photonic modes are limited by the so-called light cone, which depicts free-photon dispersion relations in the surrounding medium. Here we show that projection of the light cone on extended BZs provides a geometric method to observe radiated electromagnetic fields of photonic lattice modes. We developed a coupled dipole radiation theory to reveal how lattice geometry and dipole orientation affect the angular distributions of the radiated fields. Using dye molecules as local dipole emitters to excite and probe the optical modes, we experimentally identified high-order BZ edges through directional, in-plane lasing emission.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

The sunspot chromosphere-corona transition region

Data from simultaneous readings of the line intensities, Doppler shifts, and line widths of a sunspot ion emission lines between 1170-1700 A are reported. Subsonic and supersonic flows were observed in the same line of sight above the umbra. A reduction of coronal plasma over sunspots with an electron temperature exceeding 1,000,000 K was confirmed, concurrent with enhanced emission from the transition region plasma in the temperature range 200,000-1,000,000 K. The differential emission measure is noted to have been caused to shift because of the enhancement of the transition region plasma emission, where radiative losses dominated the energy balance. Calculations of the energy balance also indicated that a detected divergence in the enthalpy flux for the umbral downflows could balance the radiative losses in the electron temperature range 30,000-200,000 K.

Nicolas, K. R.↗

Rotational modulation and flares on RS canum Venaticorum and BY Draconis stars. XVI - IUE spectroscopy and VLA observations of Gl 182( = V 1005 Orionis) in October 1983

A large flare was detected simultaneously with IUE and VLA on Gl 182 on October 5, 1983, this event showing the largest C IV flare enhancement yet observed by IUE. A smaller flare was also detected on October 4, although only with the IUE satellite. Line ratio and emission measure techniques are used to derive various physical parameters of the flares. The radiative losses in the temperature region log T(e) = 4.3-5.4 in the two flares are 2.9 x 10 to the 33rd and 8.4 x 10 to the 32nd ergs, respectively. Total radiative losses over the whole temperature range log T(e) = 4.0-8.0 are estimated to be of the order of 6.4 x 10 to the 34th and 1.1 x 10 to the 34th ergs, respectively. In the October 5, flare, a very strong ultraviolet continuum is present with a total energy of 1.9 x 10 to the 33rd ergs over the wavelength range 1250-1950 A.

Mathioudakis, M.↗

The evaporation of spherical clouds in a hot gas. II - Effects of radiation

The effects of radiation on the evaporation of spherical clouds in a hot medium are considered. The critical cloud radius at which radiative losses balance conductive heating is determined as a function of the external temperature and density. Smaller clouds evaporate, and larger clouds condense. The conditions under which the surfaces of the clouds may be detected are discussed. Net radiative losses for evaporating clouds are calculated, and an effective cooling function for a cloudy medium is obtained. The results may be applied to clouds in supernova remnants, in the interstellar medium, and in clusters of galaxies.

Mckee, C. F.↗

3D-Stereoscopic Analysis of Solar Active Region Loops: SoHo/EIT Observations at Temperatures of 1.5-2.5 MK - 2

In this paper we study the three-dimensional (3D) structure of hot (T(sub e) approximately equals 1.5 - 2.5 MK) loops in solar active region NOAA 7986, observed on 1996 August 30 with the Extreme-ultraviolet Imaging Telescope (EIT) onboard the Solar and Heliospheric Observatory (SoHO). This complements a first study on cooler (T(sub e) approximately equals 1.0 - 1.5 MK) loops of the same active region, using the same method of Dynamic Stereoscopy to reconstruct the 3D geometry. We reconstruct the 3D-coordinates x(s), y(s), z(s), the density n(sub e)(s), and temperature profile T(sub e)(s) of 35 individual loop segments (as function of the loop coordinate s) using EIT 195 A and 284 A images. The major findings are: (1) All loops are found to be in hydrostatic equilibrium, in the entire temperature regime of T(sub e) = 1.0 - 2.5 MK; (2) The analyzed loops have a height of 2-3 scale heights, and thus only segments extending over about one vertical scale height have sufficient emission measure contrast for detection; (3) The temperature gradient over the lowest scale height is of order dT/ds is approximately 1 - 4 K/km; (4) The radiative loss rate is found to exceed the conductive loss rate by about two orders or magnitude, making thermal conduction negligible to explain the temperature structure of the loops; (5) A steady-state can only be achieved when the heating rate E(sub H) matches the radiative loss rate in hydrostatic equilibrium, requiring a heat deposition length lambda(sub H) of the half density scale height lambda, predicting a scaling law with the loop base pressure, EH varies as p(sub 0 exp 2). This favors coronal heating mechanisms that operate near the loop footpoints; (6) We find a reciprocal correlation between the loop pressure p(sub 0) and loop length L, i.e. p(sub 0) varies as 1/L, implying a scaling law of the steady-state requirement with loop length, i.e. E(sub H ) varies as 1/L(exp 2). The heating rate shows no correlation with the loop-aligned magnetic field component B(sub z) at the footpoints, but is correlated with the azimuthal field B(sub phi) = Bz(RDelta Phi/L) of a twisted loop, and is thus consistent with heating mechanisms based on field-aligned currents.

Aschwanden, Markus J.↗

High resolution EUV structure of the chromosphere-corona transition region above a sunspot

Rocket observations are reported for a sunspot at high spatial and spectral resolution in the extreme ultraviolet region (EUV) between 1170 and 1715 A. The instrument and data reduction are described, and the appearance of the sunspot features in EUV emission lines is presented together with a correlation of the nonthermal velocity field with the Doppler velocity field. For sunspots the shape of the differential emission measure curve shows that the minimum is shifted to lower temperatures by over a factor of two, while the slope on a log-log scale near log of effective temperature equal to 5.3 is increased by a factor of two. This means that the energy balance is dominated by radiative losses from the large amount of transition region plasma, and an upper limit of a million K exists on the extrapolated temperature above the umbra. Static energy balance models of the umbra show that the observed enthalpy flux can balance radiative losses above 30,000 K for a fill factor greater than 0.1. An umbral model is compared with the chromospheric sunspot model of Kneer and Mattig (1978).

Nicolas, K. R.↗

Robust and Spectrally Selective Aerogels for Solar Receivers

The development of next generation concentrated solar thermal (CST) plants requires solar receivers to reach high temperatures (> 600°C) while minimizing costs. Efficiently generating such high temperatures using a line-focusing collector and an air-stable receiver has the potential to change the current CSP paradigm because it would: (1) result in large improvements in system-level efficiency of line-focusing systems by enabling the use of high-efficiency supercritical CO 2 power cycles; (2) decrease the LCOE of line-focusing systems to meet SETO 2030 goals; (3) maintain performance over the lifetime of the CSP plant by avoiding issues related to breakdown of vacuum. The use of aerogels as transparent insulating materials (TIMs) in solar thermal receivers has the potential to enable such improvements. Specifically, aerogels can be placed in front of a black (or partially selective) high-temperature absorber to allow sunlight to transmit to the absorber but block heat from escaping. These materials can improve the efficiency and simplify the complexity of thermal transport systems by enabling operation at moderate or no vacuum levels. These potential benefits have been explicitly identified by SETO as ‘high impact’. The use of mesoporous silica as a TIM has already led to large improvements in solar collection efficiency. Nevertheless, these materials inherently lose structural integrity and the ability to suppress radiation losses at high temperatures. Here, we address these challenges by leveraging 1-cycle atomic layer deposition of aluminum oxide onto a silica aerogel to form a thermally stable interfacial layer that is transparent to sunlight but broadly absorbs in the mid-infrared. This interfacial absorption results in a two-fold reduction in measured heat losses from an absorber at 700°C and solar thermal efficiency of 81% at 700°C under 60 Suns, based on measurements of heat loss and solar transmittance. Extended-duration heat treatment reveals that the multicomponent aerogel is stable at high temperatures relative to a silica aerogel. Furthermore, we experimentally demonstrate the concept of using infrared plasmon resonances to selectively enhance the thermal absorption coefficient of TIMs in order to strongly suppress thermal radiative losses at high temperatures. We term this mechanism plasmon-enhanced greenhouse selectivity (PEGS). Unlike silica aerogels, where much of the IR absorption is lost at high temperatures, local surface plasmon resonances (LSPRs) in doped oxide nanoparticles overlap a significant portion of the blackbody spectrum and are maintained at high temperatures. Overall, this work paves the way for next-generation solar thermal energy using thermally robust transparent insulating materials.

14 SOLAR ENERGY↗

Robust and Spectrally Selective Aerogels for Solar Receivers (Final Technical Report)

The development of next generation concentrated solar thermal (CST) plants requires solar receivers to reach high temperatures (> 600°C) while minimizing costs. Efficiently generating such high temperatures using a line-focusing collector and an air-stable receiver has the potential to change the current CSP paradigm because it would: (1) result in large improvements in system-level efficiency of line-focusing systems by enabling the use of high-efficiency supercritical CO2 power cycles; (2) decrease the LCOE of line-focusing systems to meet SETO 2030 goals; (3) maintain performance over the lifetime of the CSP plant by avoiding issues related to breakdown of vacuum. The use of aerogels as transparent insulating materials (TIMs) in solar thermal receivers has the potential to enable such improvements. Specifically, aerogels can be placed in front of a black (or partially selective) high-temperature absorber to allow sunlight to transmit to the absorber but block heat from escaping. These materials can improve the efficiency and simplify the complexity of thermal transport systems by enabling operation at moderate or no vacuum levels. These potential benefits have been explicitly identified by SETO as ‘high impact’. The use of mesoporous silica as a TIM has already led to large improvements in solar collection efficiency. Nevertheless, these materials inherently lose structural integrity and the ability to suppress radiation losses at high temperatures. Here, we address these challenges by leveraging 1-cycle atomic layer deposition of aluminum oxide onto a silica aerogel to form a thermally stable interfacial layer that is transparent to sunlight but broadly absorbs in the mid-infrared. This interfacial absorption results in a two-fold reduction in measured heat losses from an absorber at 700°C and solar thermal efficiency of 81% at 700°C under 60 Suns, based on measurements of heat loss and solar transmittance. Extended-duration heat treatment reveals that the multicomponent aerogel is stable at high temperatures relative to a silica aerogel. Furthermore, we experimentally demonstrate the concept of using infrared plasmon resonances to selectively enhance the thermal absorption coefficient of TIMs in order to strongly suppress thermal radiative losses at high temperatures. We term this mechanism plasmon-enhanced greenhouse selectivity (PEGS). Unlike silica aerogels, where much of the IR absorption is lost at high temperatures, local surface plasmon resonances (LSPRs) in doped oxide nanoparticles overlap a significant portion of the blackbody spectrum and are maintained at high temperatures. Overall, this work paves the way for next-generation solar thermal energy using thermally robust transparent insulating materials.

14 SOLAR ENERGY↗

Classifying topology in photonic crystal slabs with radiative environments

Abstract In the recent years, photonic Chern materials have attracted substantial interest as they feature topological edge states that are robust against disorder, promising to realize defect-agnostic integrated photonic crystal slab devices. However, the out-of-plane radiative losses in those photonic Chern slabs has been previously neglected, yielding limited accuracy for predictions of these systems’ topological protection. Here, we develop a general framework for measuring the topological protection in photonic systems, such as in photonic crystal slabs, while accounting for in-plane and out-of-plane radiative losses. Our approach relies on the spectral localizer that combines the position and Hamiltonian matrices of the system to draw a real-picture of the system’s topology. This operator-based approach to topology allows us to use an effective Hamiltonian directly derived from the full-wave Maxwell equations after discretization via finite-elements method (FEM), resulting in the full account of all the system’s physical processes. As the spectral FEM-localizer is constructed solely from FEM discretization of the system’s master equation, the proposed framework is applicable to any physical system and is compatible with commonly used FEM software. Moving forward, we anticipate the generality of the method to aid in the topological classification of a broad range of complex physical systems.

77 NANOSCIENCE AND NANOTECHNOLOGY↗

Radiative properties of an artificial atom coupled to a Josephson-junction array

We study the radiative properties—the Lamb shift, Purcell decay rate, and spontaneous emission dynamics—of an artificial atom coupled to a long, multimode cavity formed by an array of Josephson junctions. Introducing a tunable coupling element between the atom and the array, we demonstrate that such a system can exhibit a crossover from a perturbative to a nonperturbative regime of light-matter interaction as one strengthens the coupling between the atom and the Josephson-junction array. As a consequence, the concept of spontaneous emission as the occupation of the local atomic site being governed by a single complex-valued exponent breaks down. This breakdown, we show, can be interpreted in terms of formation of hybrid atom-resonator modes with radiative losses that are nontrivially related to the effective coupling between individual modes. We develop a singular function expansion approach for the description of the open quantum system dynamics in such a multimode nonperturbative regime. This modal framework generalizes the normal-mode description of quantum fields in a finite volume, incorporating exact radiative losses and incident quantum noise at the delimiting surface. Our results are pertinent to recent experiments with Josephson atoms coupled to high-impedance Josephson-junction arrays.

42 ENGINEERING↗

Diagnostics of seeded RF plasmas: An experimental study related to the gaseous core reactor

Measurements of the temperature profiles in an RF argon plasma were made over magnetic field intensities ranging from 20 amp turns/cm to 80 amp turns/cm. The results were compared with a one-dimensional numerical treatment of the governing equations and with an approximate closed form analytical solution that neglected radiation losses. The average measured temperatures in the plasma compared well with the numerical treatment, though the experimental profile showed less of an off center temperature peak than predicted by theory. This may be a result of the complex turbulent flow pattern present in the experimental torch and not modeled in the numerical treatment. The radiation term cannot be neglected for argon at the power levels investigated. The closed form analytical approximation that neglected radiation led to temperature predictions on the order of 1000 K to 2000 K higher than measured or predicted by the numerical treatment which considered radiation losses.

Thompson, S. D.↗

Magnetic heating of stellar chromospheres and coronae

The theoretical discussion of magnetic heating focuses on heating by dissipation of field-aligned electric currents. Several mechanisms are set forth to account for the very high current densities needed to generate the heat, but observed radiative losses do not justify the resultant Ohmic heating rate. Tearing modes, 'turbulent resistivity', and 'hyper-resistivity' are considered to resolve the implied inefficiency of coronal heating. Because the mechanisms are not readily applicable to the sun, transverse magnetic energy flows and magnetic flare release are considered to account for the magnitude of observed radiative loss. High-resolution observations of the sun are concluded to be an efficient way to examine the issues of magnetic heating in spite of the very small spatial scales of the heating processes.

Van Ballegooijen, A. A.↗

Heating of solar and stellar chromospheres and coronae by MHD waves

The two general classes of models that deal with the required heating of stellar chromospheres and coronae assume that outer stellar atmospheres are heated by hydrodynamic or by magnetohydrodynamic (MHD) waves and that these waves are generated by turbulent motions in the stellar convection zones. This paper considers the types of MHD waves and the source of these waves in stars like sun, the efficiency of the generation of MHD waves, and the manner of propagation and energy dissipation of MHD waves. It is shown that the basic criteria for the validity of any theory of MHD wave heating must account for the mean level of heating observed in stellar chromospheres and coronae, and for the range of radiative losses observed for a given spectral type. It is also required that the MHD wave heating theory accounts for the existence of inhomogeneities in stellar atmospheres. The results obtained indicate that magnetic tube waves might supply enough energy for the chromospheric and coronal heating and might also account for the observed range of variations of stellar radiative losses for a given spectral type.

Musielak, Z. E.↗

A class of analytic solutions for the thermally balanced magnetostatic prominence sheet

A theoretical study is presented for the nonlinear interplay between magnetostatic equilibrium and energy balance in a Kippenhahn-Schlueter type solar prominence sheet. A class of theoretical models is presented, expressed in closed analytic forms, thus facilitating the direct illustration of the nonlinear physical properties. The model couples the equilibrium between magnetic field, plasma pressure, and weight on the one hand, with the balance between a rho-squared T radiative loss, a rho wave heating (where rho equals plasma density, and T equals plasma temperature), and thermal conduction channeled along magnetic field lines on the other. The steady solutions are divided into three classes, and are characterized by the total wave heating in the prominence sheet which is greater than, equal to, or less than the total radiative loss. The compaction of the plasma along the field lines, under its own weight, and the energy transport effects determine which of the three basic behaviors obtains in a particular situation. A discussion is presented of the implications of the steady solutions for the formation of prominences.

Low, B. C.↗

On the hydrodynamic interaction of shock waves with interstellar clouds. 1: Nonradiative shocks in small clouds

The interstellar medium (ISM) is inhomogeneous, with clouds of various temperatures and densities embedded in a tenuous intercloud medium. Shocks propagating through the ISM can ablate or destroy the clouds, at the same time significantly altering the properties of the intercloud medium. This paper presents a comprehensive numerical study of the simplest case of the interaction between a shock wave and a spherical cloud, in which the shock far from the cloud is steady and planar, and in which radiative losses, thermal conduction, magnetic fields, and gravitational forces are all neglected. As a result, the problem is completely specified by two numbers: the Mach number of the shock, M, and the ratio of the density of the cloud to that of the intercloud medium, Chi. For strong shocks we show that the dependence on M scales out, so the primary independent parameter is Chi. Variations from this simple case are also considered: the potential effect of radiative losses is assessed by calculations in which the ratio of specific heats in the cloud is 1.1 instead of 5/3; the effect of the initial shape of the cloud is studied by using a cylindrical cloud instead of a spherical one; and the role of the initial shock is determined by considering the case of a cloud embedded in a wind. Local adaptive mesh refinement techniques with a second-order, two-fluid, two-dimensional Godunov hydrodynamic scheme are used to address these problems, allowing heretofore unobtainable numerical resolution. Convergence studies to be described in a subsequent paper demonstrate that about 100 zones per cloud radius are needed for accurate results; previous calculations have generally used about a third of this number. The results of the calculations are analyzed in terms of global quantities which provide an overall description of te shocked cloud: the size and shape of the cloud, the mean density, the mean pressure, the mean velocity, the velocity dispersion, and the total circulation.

Klein, Richard I.↗

Opposed-flow Spreading Flames: Effect of Sub-atmospheric Pressure on Spread and Burning Rates

Flame spread over solid fuels is a canonical problem in fire science, due to its direct implications on material flammability and importance in fire development. Flames in a microgravity environment can behave very differently than on Earth, posing additional risks for spaceflight life safety. Sub-atmospheric pressures in ground-based experiments have been proposed to approximately replicate the burning behavior of solid fuels in reduced gravity conditions because of similar effects on heat and mass transfer mechanisms from the flame to the solid. In opposed-flow flame spread, the solid fuel is heated by the flame ahead of its leading edge, and this process is strongly affected by the ambient conditions. In this work, we consider flames spreading over flat thin acrylic samples exposed to a forced flow of 20 cm/s, and pressures between 30 and 100 kPa. When radiation losses and chemical kinetic effects are neglected, experimental and theoretical results suggest an independence of the spread rate on pressure. However, the spread rate shows a decreasing trend with lower pressure in the range 30-60 kPa. The mass burning rate, calculated from the samples weight measured before and after the experiments, shows a similar trend. The flame length, on the other hand, shows a non-monotonic behavior, reaching a maximum at 60 kPa. Additionally, gas emissions measured during the experiments are used to estimate the heat release rate of the spreading flames. The comparison of the heat release rate obtained from the measured emissions and the estimated mass burning rates, suggests that chemical kinetics is not driving the decrease in flame spread observed at low pressures, whereas radiation losses could be responsible in analogy to what has been observed in micro and partial gravity studies. These results could provide more information to guide future Earth-based material flammability testing for spacecraft applications.

fire↗

The possible role of high-frequency waves in heating solar coronal loops

We investigate the role of high-frequency waves in the heating of solar active region coronal loops. We assume a uniform background magnetic field, and we introduce a density stratification in a direction perpendicular to this field. We focus on ion compressive viscosity as the damping mechanism of the waves. We incorporate viscosity self-consistently into the equations, and we derive a dispersion relation by adopting a slab model, where the density inside the slab is greater than that outside. Such a configuration supports two types of modes: surface waves and trapped body waves. In order to determine under what conditions these waves may contribute to the heating of active regions, we solve our dispersion relation for a range of densities, temperatures, magnetic field strengths, density ratios, wavevector magnitudes, wavevector ratios, and slab widths. We find that surface waves exhibit very small damping, but body waves can potentially damp at rates needed to balance radiative losses. However, the required frequencies of these body waves are very high. For example, the wave frequency must be at least 5.0/s for a slab density of 10(exp 9,5)/cc, a slab temperature of 10(exp 6,5) K, a field strength of 100 G, and a density ratio of 5. For a slab density of 10(exp 10)/cc, this frequency increases to 8.8/s. Although these frequencies are very high, there in no observational evidence to rule out their existence, and they may be generated both below the corona and at magnetic reconnection sites in the corona. However, we do find that, for slab densities of 10(exp 10)/cc or less, the dissipation of high-frequency waves will be insufficient to balance the radiative losses if the magnetic field strength exceeds roughly 200 G. Because the magnetic field is known to exceed 200 G in many active region loops, particularly low-lying loops and loops emanating from sunspots, it is unlikely that high-frequency waves can provide sufficient heating in these regions.

Porter, Lisa J.↗