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At least 91 records · Page 5

Model of metabolism and gene expression predicts proteome allocation in Pseudomonas putida

Abstract The genome-scale model of metabolism and gene expression (ME-model) forPseudomonas putidaKT2440,iPpu1676-ME, provides a comprehensive representation of biosynthetic costs and proteome allocation. Compared to a metabolic-only model,iPpu1676-ME significantly expands on gene expression, macromolecular assembly, and cofactor utilization, enabling accurate growth predictions without additional constraints. Multi-omics analysis using RNA sequencing and ribosomal profiling data revealed translational prioritization inP. putida, with core pathways, such as nicotinamide biosynthesis and queuosine metabolism, exhibiting higher translational efficiency, while secondary pathways displayed lower priority. Notably, the ME-model significantly outperformed the M-model in alignment with multi-omics data, thereby validating its predictive capacity. Thus,iPpu1676-ME offers valuable insights intoP. putida’s proteome allocation and presents a powerful tool for understanding resource allocation in this industrially relevant microorganism.

Mathematical & Computational Biology↗

Addressing Function Allocation for the Digital Transformation of Existing Nuclear Power Plants

The existing nuclear power plants in the United States (U.S.) have a vital role in providing carbon-free electricity. For the existing nuclear power plant fleet to remain economically viable, a significant digital transformation that fundamentally changes the way in which these plants are operated, maintained, and supported ought to be seriously considered. Safe and reliable automation is needed. This work describes important considerations and challenges that come with function allocation for the adoption of new automation at existing nuclear power plants. Specifically, this work reviews the state-of-the-art in function allocation guidance and highlights how it can be used within the U.S. nuclear industry. An objective of this work is to present the current challenges and proposed approaches to the human factors community to support future research and development that ultimately supports the effective use of function allocation in the digital transformation of existing nuclear power plants.

99 GENERAL AND MISCELLANEOUS↗

Shifting the Inertial Navigation Paradigm with MEMS Technology

Why don t you use MEMS? is one of the most common questions posed to navigation systems engineers designing inertial navigation solutions in the modern era. The question stems from a general understanding that great strides have been made in terrestrial MEMS accelerometers and attitude rate sensors in terms of accuracy, mass, and power. Yet, when compared on a unit-to-unit basis, MEMS devices do not provide comparable performance (accuracy) to navigation grade sensors. This paper will propose a paradigm shift where the comparison in performance is between multiple MEMS devices and a single navigation grade sensor. The concept is that systematically, a sufficient number of MEMS sensors may mathematically provide comparable performance to a single navigation grade device and be competitive in terms power and mass allocations when viewed on a systems level. The implication is that both inertial navigation system design and fault detection, identification, and recovery could benefit from a system of MEMS devices in the same way that swarm sensing has benefited Earth observation and astronomy. A survey of the state of the art in inertial sensor accuracy scaled by mass and power will be provided to show the specific error in MEMS and navigation graded devices, a mathematical comparison of multi-unit to single-unit sensor errors will be developed, and preliminary applications to Constellation vehicles will be explored.

Crain, Timothy↗

Shifting the Intertial Navigation Paradigm with the MEMS Technology

"Why don't you use MEMS?" is of the most common questions posed to navigation systems engineers designing inertial navigation solutions in the modern era. The question stems from a general understanding that great strides have been made in terrestrial MEMS accelerometers and attitude rate sensors in terms of accuracy, mass, and power. Yet, when compared on a unit-to-unit basis, MEMS devices do not provide comparable performance (accuracy) to navigation grade sensors in several key metrics. This paper will propose a paradigm shift where the comparison in performance is between multiple MEMS devices and a single navigation grade sensor. The concept is that systematically, a sufficient number of MEMS sensors may mathematically provide comparable performance to a single navigation grade device and be competitive in terms power and mass allocations when viewed on a systems level. The implication is that both inertial navigation system design and fault detection, identification, and recovery could benefit from a system of MEMS devices in the same way that swarm sensing has benefited Earth observation and astronomy. A survey of the state of the art in inertial sensor accuracy scaled by mass and power will be provided to show the scaled error in MEMS and navigation graded devices, a mathematical comparison of multi-unit to single-unit sensor errors will be developed, and preliminary application to an Orion lunar skip atmospheric entry trajectory will be explored.

Crain, Timothy P., II↗

Advanced technology for a satellite multichannel demultiplexer/demodulator

Satellite on-board processing is needed to efficiently service multiple users while at the same time minimizing earth station complexity. The processing satellite receives a wideband uplink at 30 GHz and down-converts it to a suitable intermediate frequency. A multichannel demultiplexer then separates the composite signal into discrete channels. Each channel is then demodulated by bulk demodulators, with the baseband signals routed to the downlink processor for retransmission to the receiving earth stations. This type of processing circumvents many of the difficulties associated with traditional bent-pipe repeater satellites. Uplink signal distortion and interference are not retransmitted on the downlink. Downlink power can be allocated in accordance with user needs, independent of uplink transmissions. This allows the uplink users to employ different data rates as well as different modulation and coding schemes. In addition, all downlink users have a common frequency standard and symbol clock on the satellite, which is useful for network synchronization in time division multiple access schemes. The purpose of this program is to demonstrate the concept of an optically implemented multichannel demultiplexer (MCD). A proof-of-concept (POC) model has been developed which has the ability to receive a 40 MHz wide composite signal consisting of up to 1000 40 kHz QPSK modulated channels and perform the demultiplexing process. In addition a set of special test equipment (STE) has been configured to evaluate the performance of the POC model. The optical MCD is realized as an acousto-optic spectrum analyzer utilizing the capability of Bragg cells to perform the required channelization. These Bragg cells receive an optical input from a laser source and an RF input (the signal). The Bragg interaction causes optical output diffractions at angles proportional to the RF input frequency. These discrete diffractions are optically detected and output to individual demodulators for baseband conversion. Optimization of the MCD design was conducted in order to achieve a compromise between two opposing sources of signal degradation: adjacent channel interference and intersymbol interference. The system was also optimized to allow simple, inexpensive ground stations communications with the MCD. These design goals led to the realization of a POC MCD which demonstrates the demultiplexing function with minimal signal degradation. Performance evaluation results using the STE equipment indicate that the dynamic range of the demultiplexer in the presence of adjacent and multiple channel loading is 40 - 50 dB. Measured bit error rate (BER) probabilities varied from the predicted theoretical results by one dB or less. The performance of the proof-of-concept model indicate that the development of a space qualified optically implemented MCD are feasible. The advantages to such an implementation include reduced size, weight and power and increased reliability when compared with electronic approaches. All of these factors are critical to on-board satellite processors. Further optimization can be conducted which trade ground station complexity and MCD performance to achieve desired system results.

Abramovitz, Irwin J.↗

Modeling occupancy-driven building loads for large and diversified building stocks through the use of parametric schedules

Building energy modeling provides a fundamental tool to assess the potential for energy efficiency to contribute to reducing world energy consumption and global emissions. Occupancy-related operations are a key source of uncertainty for building energy analysis, particularly for aggregated building stocks. At a district or city level, it is critical to estimate aggregated power load profiles for sizing power grid infrastructure, power plant capacity allocation, and energy efficiency measures. The stochastic nature of behavior-related operations complicates the creation of models that accurately capture building load profiles for entire building stocks. This research introduces a new methodology called parametric schedules to model occupancy-driven schedules for large and diverse building stocks. In contrast to computationally expensive methodologies proposed in the literature, our work does not use a recursive time-consuming step. Occupancy is estimated by the extrapolation of operation times directly from metered electric consumption data; occupancy-related schedules are stochastically assigned to each building model, guaranteeing diversity of operation times in the stock. Our procedure has been tested on a large, diversified data-set of 25,000 commercial buildings in Los Angeles, California. It proved to be able to adequately represent the stochastic schedules diversity of the stock and to refine the stock calibration process by 1%. This innovative approach represents a useful asset for utility companies, grid operators, urban planners, and balancing authorities, seeking to improve building stock modeling and better estimate the impact of energy conservation measures. – This work is part of a larger stock modeling tool called ComStock, which is under development by NREL.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Consideration of environmental noise effects in transportation planning by governmental entities

Environmental concerns are reviewed with respect to major transportation systems: the interstate highway system and commercial air transportation. The type of planning that was done for interstate highway systems is described, and the shift in social value emphasis that has become apparent since the interstate system was authorized is considered. Other topics discussed include the constitutional framework for the allocation of governmental power with respect to transportation systems planning, governmental assessment of the aircraft noise problem, and evaluating the social benefit of noise abatement.

Mayo, L. H.↗

An integrated approach to space station power system autonomous control

Space Station electrical power management must be accomplished autonomously in order to decrease both airborne and ground support costs. Attention is presently given to the augmentation of terrestrial utility algorithmic decision aids for power dispatching for space station use, using expert systems to direct power demand analyses and the integration of results into operational decisions. Functions to be thus managed encompass power scheduling, energy allocation, failure cause diagnoses, goal proposal and plan preparation, consequence evaluation, and execution plan selection. The operating states of the system are normal, preventive, emergency, and restorative.

Dolce, James L.↗

WARC 92 and some thoughts as to its impact on the NASA propagation program

The World Administrative Radio Conference of 1992 (WARC 92) was held in Torremolinos, Spain, 3 Feb. - 3 Mar. 1992. Major topics considered included shortwave broadcasting, mobile and mobile-satellite service, broadcasting satellite service (sound and HDTV), space services above 20 GHz, and space research. Considerable attention was given to the congested 1-3 GHz band in general and to Low Earth Orbit (LEO) Mobile-Satellite Service, including 'little' LEO's operating below 1 GHz and to 'big' LEO's operating above 1 GHz. Significant new allocations were made for generic Mobile-Satellite Services (MSS). Proposals for allocations for uplink power control beacons and for space research received favorable treatment.

Flock, Warren L.↗

Techno-Economic Viability of Flexible Dispatch of Unconventional Geothermal Systems

Flexible geothermal operations could boost project returns through the allocation of improved power purchase agreements and/or exploitation of power price arbitrage opportunities. In this study, we investigated the techno-economic feasibility of variable flow rate control and time-of-day pricing in closed-loop geothermal systems. We considered U-shaped multilateral system configurations and modeled a variety of technical system parameters. These designs were simulated using a slender-body theory (SBT) model for transient heat transfer and fluid flow. This subsurface model was integrated into the flexible geothermal economic model (FGEM) tool to evaluate the overall flexible geothermal system techno-economics. Future hourly ambient temperature conditions were based on the Sup3rCC dataset. Published datasets were used for future hourly wholesale electricity prices. We analyzed four operating strategies: 1) baseload operation, 2) seasonal dispatch (high flow rate during summer and nominal flow rate during the rest of the year), 3) net generation maximization by varying flow rate to maximize net power output, and 4) revenue maximization by varying flow rate to maximize revenue. We ran all four scenarios for a multiloop configuration with 12 lateral passes, 7-km vertical depth and 87-km total drilling length. Furthermore, we assumed a 60 degrees C/km geothermal gradient and ambient temperature and wholesale electricity prices for New Mexico as a typical state location. The nominal flow rate was set to 80 kg/s. When considering drilling costs of $1,000/m and a discount rate of 7%, the generation maximization scenario resulted in the lowest levelized cost of electricity (LCOE) of ~$150/MWh. When considering project return on investment (ROI), defined as lifetime net income divided by upfront capital costs, all flexible operation scenarios performed better than the base case scenario. The highest ROI of 80% was obtained with the revenue maximization scenario. With drilling costs of $200/m and a discount rate of 5%, the generation maximization scenario resulted in LCOE of $49/MWh.

flexible geothermal↗

An expansion plan for the 60 Hz power distribution system at KSC: LC-39 substations load allocation plan

The increasing load density in the LC-39 area of Kennedy Space Center (KSC) can be met by either modifying the existing substation and increasing its capacity or by planning an additional new substation. Evidence that the later approach is more economical, enhances the system reliability, and would produce more satisfactory performance indices is provided. Network theory is the basis for the optimal location determination of the proposed substation. A load reallocation plan which minimizes investment cost and power losses and meets other desirable system features is drafted. The report should be useful to the system designer and can be a useful guideline for future facility planners.

Kalu, Alex↗

Development of a Smooth Trajectory Maneuver Method to Accommodate the Ares I Flight Control Constraints

Six degree-of-freedom (DOF) launch vehicle trajectories are designed to follow an optimized 3-DOF reference trajectory. A vehicle has a finite amount of control power that it can allocate to performing maneuvers. Therefore, the 3-DOF trajectory must be designed to refrain from using 100% of the allowable control capability to perform maneuvers, saving control power for handling off-nominal conditions, wind gusts and other perturbations. During the Ares I trajectory analysis, two maneuvers were found to be hard for the control system to implement; a roll maneuver prior to the gravity turn and an angle of attack maneuver immediately after the J-2X engine start-up. It was decided to develop an approach for creating smooth maneuvers in the optimized reference trajectories that accounts for the thrust available from the engines. A feature of this method is that no additional angular velocity in the direction of the maneuver has been added to the vehicle after the maneuver completion. This paper discusses the equations behind these new maneuvers and their implementation into the Ares I trajectory design cycle. Also discussed is a possible extension to adjusting closed-loop guidance.

Pinson, Robin M.↗

Automated electric power management and control for Space Station Freedom

A comprehensive automation design is being developed for Space Station Freedom's electric power system. It strives to increase station productivity by applying expert systems and conventional algorithms to automate power system operation. An integrated approach to the power system command and control problem is defined and used to direct technology development in: diagnosis, security monitoring and analysis, battery management, and cooperative problem-solving for resource allocation. The prototype automated power system is developed using simulations and test-beds.

Dolce, James L.↗

Automated electric power management and control for Space Station Freedom

A comprehensive automation design is being developed for Space Station Freedom's electric power system. It strives to increase station productivity by applying expert systems and conventional algorithms to automate power system operation. An integrated approach to the power system command and control problem is defined and used to direct technology development in: diagnosis, security monitoring and analysis, battery management, and cooperative problem-solving for resource allocation. The prototype automated power system is developed using simulations and test-beds.

Dolce, James L.↗

Innovative Approach for Developing Spacecraft Interior Acoustic Requirement Allocation

The Orion Multi-Purpose Crew Vehicle (MPCV) is an American spacecraft for carrying four astronauts during deep space missions. This paper describes an innovative application of Power Injection Method (PIM) for allocating Orion cabin continuous noise Sound Pressure Level (SPL) limits to the sound power level (PWL) limits of major noise sources in the Environmental Control and Life Support System (ECLSS) during all mission phases. PIM is simulated using both Statistical Energy Analysis (SEA) and Hybrid Statistical Energy Analysis-Finite Element (SEA-FE) models of the Orion MPCV to obtain the transfer matrix from the PWL of the noise sources to the acoustic energies of the receivers, i.e., the cavities associated with the cabin habitable volume. The goal of the allocation strategy is to control the total energy of cabin habitable volume for maintaining the required SPL limits. Simulations are used to demonstrate that applying the allocated PWLs to the noise sources in the models indeed reproduces the SPL limits in the habitable volume. The effects of Noise Control Treatment (NCT) on allocated noise source PWLs are investigated. The measurement of source PWLs of involved fan and pump development units are also discussed as it is related to some case-specific details of the allocation strategy discussed here.

Chu, S. Reynold↗

Innovative Approach for Developing Spacecraft Interior Acoustic Requirement Allocation

The Orion Multi-Purpose Crew Vehicle (MPCV) is an American spacecraft for carrying four astronauts during deep space missions. This paper describes an innovative application of Power Injection Method (PIM) for allocating Orion cabin continuous noise Sound Pressure Level (SPL) limits to the sound power level (PWL) limits of major noise sources in the Environmental Control and Life Support System (ECLSS) during all mission phases. PIM is simulated using both Statistical Energy Analysis (SEA) and Hybrid Statistical Energy Analysis-Finite Element (SEA-FE) models of the Orion MPCV to obtain the transfer matrix from the PWL of the noise sources to the acoustic energies of the receivers, i.e., the cavities associated with the cabin habitable volume. The goal of the allocation strategy is to control the total energy of cabin habitable volume for maintaining the required SPL limits. Simulations are used to demonstrate that applying the allocated PWLs to the noise sources in the models indeed reproduces the SPL limits in the habitable volume. The effects of Noise Control Treatment (NCT) on allocated noise source PWLs are investigated. The measurement of source PWLs of involved fan and pump development units are also discussed as it is related to some case-specific details of the allocation strategy discussed here.

Chu, S. Reynold↗

The Lightweight Integrated Solar Array and Transceiver (LISA-T): Second Generation Advancements and the Future of SmallSat Power Generation

This paper describes the second generation advancements of the Lightweight Integrated Solar Array and Transceiver (LISA-T) currently being developed at NASA's Marshall Space Flight Center. LISA-T is a launch stowed, orbit deployed array on which thin-film photovoltaic and antenna elements are embedded. Inherently, small satellites are limited in surface area, volume, and mass allocation; driving competition between power, communications, and GN&C (guidance navigation and control) subsystems. This restricts payload capability and limits the value of these low-cost satellites. LISA-T is addressing this issue, deploying large-area arrays from a reduced volume and mass envelope - greatly enhancing power generation and communications capabilities of small spacecraft. A matrix of options are in development, including planar (pointed) and omnidirectional (non-pointed) arrays. The former is seeking the highest performance possible while the latter is seeking GN&C simplicity. In both cases, power generation ranges from tens of watts to several hundred with an expected specific power >250W/kg and a stowed power density >200kW/m(sub 3). Options for leveraging both high performance, 'typical cost' triple junction thin-film solar cells as well as moderate performance, low cost cells are being developed. Alongside, both UHF (ultra high frequency) and S-band antennas are being integrated into the array to move their space claim away from the spacecraft and open the door for omnidirectional communications and electronically steered phase arrays.

Carr, John A.↗