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At least 91 records · Page 5

Continental Patterns of Bird Migration Linked to Climate Variability

For nearly 100 years, avian migration studies have divided North America into three or four primary flyways, at times based on subjective approaches or just for convenience. Those studies often fail to adequately reflect a critical characterization of migration —phenology. This shortcoming has been partly due to the lack of reliable continental-scale data, a gap filled by our current study. Here, we leveraged unique radar-based data quantifying migration phenology and used an objective regionalization approach to revisit the traditional spatial framework. Consequently, we identified two regions with distinct inter annual variability of spring migration across the contiguous U.S. This new data-driven framework has enabled us to explore the climatic cues affecting the inter annual variability of migration phenology, “specific to each region” across North America. For example, our “two-region” approach allowed us to identify an east-west dipole pattern in migratory behavior linked to atmospheric Ross by waves. Also, we revealed a low-frequency variability in migration movements over the western U.S. that is inversely related with temperature and the Pacific Decadal Oscillation (PDO). Our spatial platform would facilitate future work on better understanding the mechanisms responsible for broad-scale migration phenology and its potential future changes.

Atmosphere↗

Method and apparatus for inter-lane thread migration

Briefly, methods and apparatus to migrate a software thread from one wavefront executing on one execution unit to another wavefront executing on another execution unit whereby both execution units are associated with a compute unit of a processing device such as, for example, a GPU. The methods and apparatus may execute compiled dynamic thread migration swizzle buffer instructions that when executed allow access to a dynamic thread migration swizzle buffer that allows for the migration of register context information when migrating software threads. The register context information may be located in one or more locations of a register file prior to storing the register context information into the dynamic thread migration swizzle buffer. The method and apparatus may also return the register context information from the dynamic thread migration swizzle buffer to one or more different register file locations of the register file.

97 MATHEMATICS AND COMPUTING↗

Cation Migration in Physically Paired 2D and 3D Lead Halide Perovskite Films

2D/3D interfaces provide long-term stability for the operation of metal halide perovskite solar cells. However, the cation migration under heat and light can disturb the interface and create a graded cation interface. This study has now probed the cation migration by physically pairing X 2 PbI 4 (X = butylammonium BA, oleylammonium OA, or phenethylammonium PEA) 2D film and (CH 3 NH 3 , MA)PbI 3 3D film at different temperatures and recording changes in the absorption and emission spectra. The migration of the methyl ammonium cation toward the 2D film slowly transforms the n = 1 layered phase into n = 2 and 3 layered phases. The 3D film, on the other hand, exhibits relatively small changes, as the inclusion of spacer cation has little effect on its phase. The apparent activation energy determined from the temperature-dependent cation migration kinetics (E a = 29– 50 kJ mol –1 ) indicates alkyl ammonium cations such as butyl ammonium migrate more readily into the 3D layer than aromatic cations such as PEA. As a result, the ease of migration of spacer cations between physically paired films suggests that the varied composition at the interface should be considered while evaluating the effectiveness of the 2D/3D design strategy for improving the performance of perovskite solar cells.

2D/3D perovskite↗

Mapping the pathways of photo-induced ion migration in organic-inorganic hybrid halide perovskites

Abstract Organic-inorganic hybrid perovskites exhibiting exceptional photovoltaic and optoelectronic properties are of fundamental and practical interest, owing to their tunability and low manufacturing cost. For practical applications, however, challenges such as material instability and the photocurrent hysteresis occurring in perovskite solar cells under light exposure need to be understood and addressed. While extensive investigations have suggested that ion migration is a plausible origin of these detrimental effects, detailed understanding of the ion migration pathways remains elusive. Here, we report the characterization of photo-induced ion migration in perovskites using in situ laser illumination inside a scanning electron microscope, coupled with secondary electron imaging, energy-dispersive X-ray spectroscopy and cathodoluminescence with varying primary electron energies. Using methylammonium lead iodide and formamidinium lead iodide as model systems, we observed photo-induced long-range migration of halide ions over hundreds of micrometers and elucidated the transport pathways of various ions both near the surface and inside the bulk of the samples, including a surprising finding of the vertical migration of lead ions. Our study provides insights into ion migration processes in perovskites that can aid perovskite material design and processing in future applications.

14 SOLAR ENERGY↗

The use of nocturnal flights for barrier crossing in a diurnally migrating songbird

The migration patterns of land birds can generally be divided into those species that migrate principally during the day and those that migrate during the night. Some species may show individual plasticity in the use of day or night flight, particularly when crossing large, open-water or desert barriers. However, individual plasticity in circadian patterns of migratory flights in diurnally migrating songbirds has never been investigated. We used high precision GPS tracking of a diurnal, migratory swallow, the purple martin (Progne subis), to determine whether individuals were flexible in their spring migration strategies to include some night flight, particularly at barrier crossing. Most (91%) of individuals made large (sometimes > 1000 km), open-water crossings of the Caribbean Sea and the Gulf of Mexico that included the use of night flight. 32% of all water crossings were initiated at night, demonstrating that night flight is not only used to complete large crossings but may confer other advantages for diurnal birds. Birds were not more likely to initiate crossings with supportive winds, however crossings were more likely when they reduced travel distances. Our results are consistent with diurnal birds using night flight to help achieve time- and energy-savings through ‘short cuts’ at barrier crossings, at times and locations when foraging opportunities are not available. Overall, our results demonstrate the use of nocturnal flight and a high degree of individual plasticity in migration strategies on a circadian scale in a species generally considered to be a diurnal migrant. Nocturnal flights at barrier crossing may provide time and energy savings where foraging opportunities are low in an otherwise diurnal strategy. Future research should target how diel foraging and refueling strategies support nocturnal flights and barrier crossing in this and other diurnal species.

54 ENVIRONMENTAL SCIENCES↗

TRPV4 promotes the migration and invasion of glioma cells via AKT/Rac1 signaling

Highlights: • TRPV4 is upregulated in glioma, and high-level of TRPV4 indicates a worse prognosis. • TRPV4 activation enhances the cell migration and invasion of glioma. • TRPV4-induced cell motility via AKT/Rac1 signaling pathway. Experimental evidence indicates a critical role of TRPV4 (Transient Receptor Potential Vanilloid 4) in controlling the cell migratory activity of multiple tumors. However, the oncogenic role of TRPV4 in glioma still remains elusive. In this study, we tried to investigate the oncogenic role of TRPV4 in glioma. We found that the expression levels of TRPV4 were upregulated in glioma and the high levels of TRPV4 indicated a worse prognosis in patients with glioma. TRPV4 was critical for glioma migration and invasion: activating TRPV4 by agonist GSK1016790 A enhanced glioma migration and invasion, while, the specific TRPV4 antagonist HC-067047 suppressed glioma migration and invasion. Mechanically, activated TRPV4 promoted the activation of Rac1 (Ras-related C3 botulinum toxin substrate 1) by targeting the AKT for phosphorylation, then enhanced glioma migration and invasion. All these results suggested that TRPV4 accelerates glioma migration and invasion through the AKT/Rac1 signaling, and TRPV4 might be considered as a potential target for glioma therapy.

60 APPLIED LIFE SCIENCES↗

Advancing spatiotemporal forecasts of CO 2 plume migration using deep learning networks with transfer learning and interpretation analysis

Accurate and timely forecasts of CO 2 plume distribution throughout the injection and post-injection phases are crucial for detecting plume migration, assessing leakage risks, and supporting operational decisions in geologic carbon storage (GCS). Current convolutional neural network-based approaches primarily focus on spatial information and overlook temporal dependencies in plume distributions, thus limiting their ability to capture dynamic movement effects and provide accurate predictions of plume migration. In this work, we propose two deep learning models, Auto-Encoder (AE)-LSTM and Encoder-Decoder (ED)-ConvLSTM, each uniquely designed to capture both spatial and temporal features. We apply the proposed methods to forecast the dynamic distribution of CO 2 plumes based on 108 reservoir simulations over a 30-year injection and a 30-year post-injection period. The results indicate that the ED-ConvLSTM model outperforms the AE-LSTM model in accurately predicting the spatiotemporal dynamics of CO 2 plume migration, achieving R 2 values above 0.99. To provide a deeper understanding of these model predictions, we employ a gradient-based explanation method on the trained models. This approach provides insights into the influence of input variables on plume migration forecasts and uncovers the underlying prediction mechanisms of the proposed models. Furthermore, we introduce a transfer learning technique, enabling fast and accurate plume migration forecasting in the post-injection phase by leveraging the trained model during the injection phase. This reduces the necessity for extensive data collection or re-training. In conclusion, the methods proposed in our work enhances the performance and interpretability of CO 2 plume migration forecasts, thereby facilitating informed decision-making throughout the entire lifecycle of GCS applications.

58 GEOSCIENCES↗

The actomyosin network is influenced by NMHC IIA and regulated by CrpF46, which is involved in controlling cell migration

Highlights: • Crp{sup F46} knockdown in cells hindered cell migration. • Crp{sup F46} knockdown disturbed MT arrangement and centrosomal reorientation. • Crp{sup F46} knockdown induced weak stress fiber formation. • Crp{sup F46} interacted with NMHC IIA with its three coiled-coil domains. • Myosin filaments are regulated by Crp{sup F46} associated with phosphorylation of myosin. When a cell migrates, the centrosome positions between the nucleus and the leading edge of migration via the microtubule system. The protein Crp{sup F46} (centrosome-related protein F46) has a known role during mitosis and centrosome duplication. However, how Crp{sup F46} efficiently regulates centrosome-related cell migration is unclear. Here, we report that knockdown of Crp{sup F46} resulted in the disruption of microtubule arrangement, with impaired centrosomal reorientation, and slowed down cell migration. In cells that express low levels of Crp{sup F46}, stress fibers were weakened, which could be rescued by recovering Flag-Crp{sup F46}. We also found that Crp{sup F46} interacted with non-muscle myosin high chain IIA (NMHC IIA) and that its three coiled-coil domains are pivotal for its binding to NMHC IIA. Additionally, analyses of phosphorylation of NMHC IIA and RLC (regulatory light chain) demonstrated that Crp{sup F46} was associated with myosin IIA during filament formation. Indirect immunofluorescence images indicated that NM IIA filaments were inhibited when Crp{sup F46} was under-expressed. Thus, Crp{sup F46} regulates cell migration by centrosomal reorientation and altering the function of the actomyosin network by controlling specific phosphorylation of myosin.

60 APPLIED LIFE SCIENCES↗

Time-resolved molecular dynamics of single and double hydrogen migration in ethanol

Being the lightest, most mobile atom that exists, hydrogen plays an important role in the chemistry of hydrocarbons, proteins and peptides and most biomolecules. Hydrogen can undergo transfer, exchange and migration processes, having considerable impact on the chemical behavior of these molecules. Although much has been learned about reaction dynamics involving one hydrogen atom, less is known about those processes where two or more hydrogen atoms participate. Here we show that single and double hydrogen migrations occurring in ethanol cations and dications take place within a few hundred fs to ps, using a 3D imaging and laser pump-probe technique. For double hydrogen migration, the hydrogens are not correlated, with the second hydrogen migration promoting the breakup of the C–O bond. The probability of double hydrogen migration is quite significant, suggesting that double hydrogen migration plays a more important role than generally assumed. The conclusions are supported by state-of-the-art molecular dynamics calculations.

08 HYDROGEN↗

Voltage decay and redox asymmetry mitigation by reversible cation migration in lithium-rich layered oxide electrodes

Despite the high energy density of lithium-rich layered-oxide electrodes, their real-world implementation in batteries is hindered by the substantial voltage decay on cycling. This voltage decay is widely accepted to mainly originate from progressive structural rearrangements involving irreversible transition-metal migration. As prevention of this spontaneous cation migration has proven difficult, a paradigm shift toward management of its reversibility is needed. Herein, we demonstrate that the reversibility of the cation migration of lithium-rich nickel manganese oxides can be remarkably improved by altering the oxygen stacking sequences in the layered structure and thereby dramatically reducing the voltage decay. The preeminent intra-cycle reversibility of the cation migration is experimentally visualized, and first-principles calculations reveal that an O2-type structure restricts the movements of transition metals within the Li layer, which effectively streamlines the returning migration path of the transition metals. Furthermore, we propose that the enhanced reversibility mitigates the asymmetry of the anionic redox in conventional lithium-rich electrodes, promoting the high-potential anionic reduction, thereby reducing the subsequent voltage hysteresis. Our findings demonstrate that regulating the reversibility of the cation migration is a practical strategy to reduce voltage decay and hysteresis in lithium-rich layered materials.

25 ENERGY STORAGE↗

Climate change as an incentive for future human migration

Human migration is both motivated and constrained by a multitude of socioeconomic and environmental factors, including climate-related factors. Climatic factors exert an influence on local and regional population density. Here, we examine the implications of future motivation for humans to migrate by analyzing today's relationships between climatic factors and population density, with all other factors held constant. Such “all other factors held constant” analyses are unlikely to make quantitatively accurate predictions, but the order of magnitude and spatial pattern that come out of such an analysis can be useful when considering the influence of climate change on the possible scale and pattern of future incentives to migrate. Our results indicate that, within decades, climate change may provide hundreds of millions of people with additional incentive to migrate, largely from warm tropical and subtropical countries to cooler temperate countries, with India being the country with the greatest number of people with additional incentive to migrate. These climate-driven incentives would be among the broader constellation of incentives that influence migration decisions. Areas with the highest projected population growth rates tend to be areas that are likely to be most adversely affected by climate change.

54 ENVIRONMENTAL SCIENCES↗

Endothelial Cell Morphology and Migration are Altered by Changes in Gravitational Fields

Endothelial cell migration is important to vascular wall regeneration following injury or stress. However, the mechanism(s) governing this response is not well understood. The microgravity environment of space may complicate the response of these cells to injury. To date, there are no reports in this area. We examined how bovine aortic (BAEC) and pulmonary (BPEC) endothelial cells respond to denudation injury under hypergravity (HGrav) and simulated microgravity (MGrav), using image analysis. In 10% FBS, the migration of confluent BAEC and BPEC into the denuded area was not affected by HGrav or MGrav. However, in low FBS (0.5%), signficantly retarded migration under MGrav, and increased migration under HGrav was found. MGrav also decreased the migration of postconfluent BPEC while HGrav showed no difference. Both MGrav and HGrav strongly decreased the migration of postconfluent BAEC. Also, both cell lines showed significant morphological changes by scanning electron microscopy. These studies indicate that endothelial cell function is affected by changes in gravity.

Melhado, Caroline↗

Mesospheric Non-Migrating Tides Generated With Planetary Waves: II Influence of Gravity Waves

We demonstrated that, in our model, non-linear interactions between planetary waves (PW) and migrating tides could generate in the upper mesosphere non-migrating tides with amplitudes comparable to those observed. The Numerical Spectral Model (NSM) we employ incorporates Hines Doppler Spread Parameterization for small-scale gravity waves (GW), which affect in numerous ways the dynamics of the mesosphere. The latitudinal (seasonal) reversals in the temperature and zonal circulation, which are largely caused by GWs (Lindzen, 198l), filter the PWs and contribute to the instabilities that generate the PWs. The PWs in turn are amplified by the momentum deposition of upward propagating GWs, as are the migrating tides. The GWs thus affect significantly the migrating tides and PWs, the building blocks of non-migrating tides. In the present paper, we demonstrate that GW filtering also contributes to the non-linear coupling between PWs and tides. Two computer experiments are presented to make this point. In one, we simply turn off the GW source to show the effect. In the second case, we demonstrate the effect by selectively suppressing the momentum source for the m = 0 non-migrating tides.

Mayr, H. G.↗

Production of Star-Grazing and Star-Impacting Planetestimals via Orbital Migration of Extrasolar Planets

During the orbital migration of a giant extrasolar planet via ejection of planetesimals (as studied by Murray et al. in 1998), inner mean-motion resonances can be strong enough to cause planetesimals to graze or impact the star. We integrate numerically the motions of particles which pass through the 3:1 or 4:1 mean-motion resonances of a migrating Jupiter-mass planet. We find that many particles can be trapped in the 3:1 or 4:1 resonances and pumped to high enough eccentricities that they impact the star. This implies that for a planet migrating a substantial fraction of its semimajor axis, a fraction of its mass in planetesimals could impact the star. This process may be capable of enriching the metallicity of the star at a time when the star is no longer fully convective. Upon close approaches to the star, the surfaces of these planetesimals will be sublimated. Orbital migration should cause continuing production of evaporating bodies, suggesting that this process should be detectable with searches for transient absorption lines in young stars. The remainder of the particles will not impact the star but can be ejected subsequently by the planet as it migrates further inward. This allows the planet to migrate a substantial fraction of its initial semimajor axis by ejecting planetesimals.

Quillen, A. C.↗

Eccentricity Evolution of Migrating Planets

We examine the eccentricity evolution of a system of two planets locked in a mean motion resonance, in which either the outer or both planets lose energy and angular momentum. The sink of energy and angular momentum could be a gas or planetesimal disk. We analytically calculate the eccentricity damping rate in the case of a single planet migrating through a planetesimal disk. When the planetesimal disk is cold (the average eccentricity is much less than 1), the circularization time is comparable to the inward migration time, as previous calculations have found for the case of a gas disk. If the planetesimal disk is hot, the migration time can be an order of magnitude shorter. We show that the eccentricity of both planetary bodies can grow to large values, particularly if the inner body does not directly exchange energy or angular momentum with the disk. We present the results of numerical integrations of two migrating resonant planets showing rapid growth of eccentricity. We also present integrations in which a Jupiter-mass planet is forced to migrate inward through a system of 5-10 roughly Earth-mass planets. The migrating planets can eject or accrete the smaller bodies; roughly 5% of the mass (averaged over all the integrations) accretes onto the central star. The results are discussed in the context of the currently known extrasolar planetary systems.

Murray, N.↗

Focal adhesion kinase is involved in mechanosensing during fibroblast migration

Focal adhesion kinase (FAK) is a non-receptor protein tyrosine kinase localized at focal adhesions and is believed to mediate adhesion-stimulated effects. Although ablation of FAK impairs cell movement, it is not clear whether FAK might be involved in the guidance of cell migration, a role consistent with its putative regulatory function. We have transfected FAK-null fibroblasts with FAK gene under the control of the tetracycline repression system. Cells were cultured on flexible polyacrylamide substrates for the detection of traction forces and the application of mechanical stimulation. Compared with control cells expressing wild-type FAK, FAK-null cells showed a decrease in migration speed and directional persistence. In addition, whereas FAK-expressing cells responded to exerted forces by reorienting their movements and forming prominent focal adhesions, FAK-null cells failed to show such responses. Furthermore, FAK-null cells showed impaired responses to decreases in substrate flexibility, which causes control cells to generate weaker traction forces and migrate away from soft substrates. Cells expressing Y397F FAK, which cannot be phosphorylated at a key tyrosine site, showed similar defects in migration pattern and force-induced reorientation as did FAK-null cells. However, other aspects of F397-FAK cells, including the responses to substrate flexibility and the amplification of focal adhesions upon mechanical stimulation, were similar to that of control cells. Our results suggest that FAK plays an important role in the response of migrating cells to mechanical input. In addition, phosphorylation at Tyr-397 is required for some, but not all, of the functions of FAK in cell migration.

NASA Discipline Cell Biology↗

Migration of lymphocytes on fibronectin-coated surfaces: temporal evolution of migratory parameters

Lymphocytes typically interact with implanted biomaterials through adsorbed exogenous proteins. To provide a more complete characterization of these interactions, analysis of lymphocyte migration on adsorbed extracellular matrix proteins must accompany the commonly performed adhesion studies. We report here a comparison of the migratory and adhesion behavior of Jurkat cells (a T lymphoblastoid cell line) on tissue culture treated and untreated polystyrene surfaces coated with various concentrations of fibronectin. The average speed of cell locomotion showed a biphasic response to substrate adhesiveness for cells migrating on untreated polystyrene and a monotonic decrease for cells migrating on tissue culture-treated polystyrene. A modified approach to the persistent random walk model was implemented to determine the time dependence of cell migration parameters. The random motility coefficient showed significant increases with time when cells migrated on tissue culture-treated polystyrene surfaces, while it remained relatively constant for experiments with untreated polystyrene plates. Finally, a cell migration computer model was developed to verify our modified persistent random walk analysis. Simulation results suggest that our experimental data were consistent with temporally increasing random motility coefficients.

NASA Program Fundamental Space Biology↗

Space-Based Ornithology - Studying Bird Migration and Environmental Change in North America

Natural fluctuations in the availability of critical stopover sites coupled with anthropogenic destruction of wetlands, land-use change, and anticipated losses due to climate change present migratory birds with a formidable challenge. Space based technology in concert with bird migration modeling and geographical information analysis yields new opportunities to shed light on the distribution and movement of organisms on the planet and their sensitivity to human disturbances and environmental changes. At the NASA Goddard Space Flight Center, we are creating ecological forecasting tools for science and application users to address the consequences of loss of wetlands, flooding, drought or other natural disasters such as hurricanes on avian biodiversity and bird migration. We use an individual-based bird biophysical migration model, driven by remotely sensed land surface data, climate and hydrologic data, and biological field observations to study migratory bird responses to environmental change in North America. Simulation allows us to study bird migration across multiple scales and can be linked to mechanistic processes describing the time and energy budget states of migrating birds. We illustrate our approach by simulating the spring migration of pectoral sandpipers from the Gulf of Mexico to Alaska. Mean stopover length and trajectory patterns are consistent with field observations.

Smith, James A.↗