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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 91 records · Page 5
All sourcesNASA NTRSDOE OSTI
NASA NTRS2003

Regional Chemistry from Global CTMs with EC-Modeled Met-fields for the TRACE-P Mission

The UC Irvine project for Trace-P (PI: Prather) is a collaboration with Frontier-Japan (Wild and Akimoto) and U. Oslo (Sundet and Isaksen) to make high-resolution global T63 CTM simulations of trace gases and the oxidant budgets for the Trace-P period. Research at FRS and Oslo is not funded by GTE/TRACE-P. Completed control runs for the Trace-P period at T63L40 resolution using the standard emissions with the two related, but independent CTMs at Frontier-UCI and at U. Oslo. Preliminary diagnosis of the impact of Asian emissions on ozone and oxidant budgets is completed. A series of sensitivity runs is beginning to analyze where uncertainty in emissions is related to better simulation of the Trace-P observations.

Prather, Michael J.↗
NASA NTRS1995

Initial Verification of the GPS-LEO Occultation Technique of Mapping the Atmosphere with the GPS-MET Experiment

The radio occultation technique was first used to observe Earth's atmosphere in April 1995 when a high performance Global Positioning System (GPS) receiver was placed into a low-Earth orbit. When a signal from the GPS travels through the ionosphere and the neutral atmosphere, and is received by a low-Earth orbiter (LEO) satellite, occultation data is generated. How that data is analyzed is presented.

GPS Global Positioning System Radio Occultation↗
NASA NTRS2015

Atmospheric Condensation in the Mars Phoenix TECP and MET Data

A new calibration function for the humidity sensor in the Thermal and Electrical Conductivity Probe (TECP), a component of the Microscopy, Electrochemistry, and Conductivity Analyzer (MECA) on the Phoenix Mars mission has been developed. The data is now cast in terms of Frost Point (T(sub f)) and some flight data, taken when the atmosphere is independently known to be saturated, is included in the calibration data set. Combined with data from the Meteorology Mast air temperature sensors, a very sensitive detection of atmospheric saturation becomes possible (Figure 1).

Microscopy↗
NASA NTRS2016

Evaluation of the Cloud Fields in the UK Met Office HadGEM3-UKCA Model Using the CCCM Satellite Data Product to Advance Our Understanding of the Influence of Clouds on Tropospheric Composition and Chemistry

To determine the role of clouds in driving inter-annual and inter-seasonal variability of trace gases in the troposphere and lower stratosphere with a particular focus on the importance of cloud modification of photolysis. To evaluate the cloud fields and their vertical distribution in the HadGEM3 model utilizing CCCM, a unique 3-D cloud data product merged from multiple A-Train satellites (CERES, CloudSat, CALIPSO, and MODIS) developed at the NASA Langley Research Center.

Varma, Sunil↗
NASA NTRS2017

Marshall Engineering Thermosphere Model, Version MET-2007

The region of the Earth's atmosphere between about 90 and 500 km altitude is known as the thermosphere, while the region above about 500 km is known as the exosphere. For space vehicle operations, the neutral atmosphere in these regions is significant. Even at its low density, it produces torques and drags on vehicles and affects orbital lifetimes. The thermosphere density above 100 km altitude also modulates the flux of trapped radiation and orbital debris. Atomic oxygen at orbital altitudes is important because it can erode and chemically change exposed vehicle surfaces.

Suggs, R. J.↗
NASA NTRSDate not supplied

Identification of Primitive Unequilibrated Ordinary Chondrites from Four Antarctic Dense Collections Areas (EET, GRO, LEW, and MET)

Unequilibrated ordinary chondrites (UOC) typically contain metal [1], primitive chondrules [2], pre-solar grains [3], organics [4], nebular materials in matrix [5], and isotopic records of early solar system processes [6], and are thus scientifically valuable samples that provide important information about the early solar system. UOCs from dense collection areas (DCA) like in the Transantarctic Mtns. pose several specific challenges. First, they are commonly part of large pairing groups for which preliminary studies are followed up by detailed studies that reveal differences among the pairs (e.g., [7,8]). Second, subsequent visits to the DCA identify and recover new members of the pairing group. Thus over time, the pairing groups must be re-assessed as new information becomes available for existing and new members of the larger pairing groups. Given the suggestion that many samples in these groups could be more primitive than L3.4 (e.g., [7]), we have undertaken a survey of 103 chondrites. Here we report olivine analyses from Type II (FeO-rich) chondrules with a goal of identifying primitive (<L3.20) UOCs using the Cr in olivine approach [9]. In the process of the detailed work, we identified 22 samples of petrologic grade 3.2 or lower that were previously unrecognized. Pairing relations of L3.x chondrites in these 3 areas are accordingly re-assessed.

chondrite↗
DOE OSTI2023

Impaired cardiac glycolysis and glycogen depletion are linked to poor myocardial outcomes in juvenile male swine with metabolic syndrome and ischemia

Abstract Obesity continues to rise in the juveniles and obese children are more likely to develop metabolic syndrome (MetS) and related cardiovascular disease. Unfortunately, effective prevention and long‐term treatment options remain limited. We determined the juvenile cardiac response to MetS in a swine model. Juvenile male swine were fed either an obesogenic diet, to induce MetS, or a lean diet, as a control (LD). Myocardial ischemia was induced with surgically placed ameroid constrictor on the left circumflex artery. Physiological data were recorded and at 22 weeks of age the animals underwent a terminal harvest procedure and myocardial tissue was extracted for total metabolic and proteomic LC/MS–MS, RNA‐seq analysis, and data underwent nonnegative matrix factorization for metabolic signatures. Significantly altered in MetS versus. LD were the glycolysis‐related metabolites and enzymes. In MetS compared with LD Glycogen synthase 1 (GYS1)‐glycogen phosphorylases (PYGM/PYGL) expression disbalance resulted in a loss of myocardial glycogen. Our findings are consistent with the concept that transcriptionally driven myocardial changes in glycogen and glucose metabolism‐related enzymes lead to a deficiency of their metabolite products in MetS. This abnormal energy metabolism provides insight into the pathogenesis of the juvenile heart in MetS. This study reveals that MetS and ischemia diminishes ATP availability in the myocardium via altering the glucose‐G6P‐pyruvate axis at the level of metabolites and gene expression of related enzymes. The observed severe glycogen depletion in MetS coincides with disbalance in expression of GYS1 and both PYGM and PYGL. This altered energy substrate metabolism is a potential target of pharmacological agents for improving juvenile myocardial function in MetS and ischemia.

Broadwin, Mark↗
NASA NTRS2004

Earth GRAM-99 and Trace Constituents

Global Reference Atmospheric Model (GRAM-99) is an engineering-level model of Earth's atmosphere. It provides both mean values and perturbations for density, temperature, pressure, and winds, as well as monthly- and geographically-varying trace constituent concentrations. From 0-27 km, GRAM thermodynamics and winds are based on National Oceanic and Atmospheric Administration Global Upper Air Climatic Atlas (GUACA) climatology. Above 120 km, GRAM is based on the NASA Marshall Engineering Thermosphere (MET) model. In the intervening altitude region, GRAM is based on Middle Atmosphere Program (MAP) climatology that also forms the basis of the 1986 COSPAR International Reference Atmosphere (CIRA). Atmospheric composition is represented in GRAM by concentrations of both major and minor species. Above 120 km, MET provides concentration values for N2, O2, Ar, O, He, and H. Below 120 km, species represented also include H2O, O3, N2O, CO, CH4, and CO2. At COSPAR 2002 a comparison was made between GRAM constituents below 120 km and those provided by Naval Research Laboratory (NRL) climatology. No current need to update GRAM constituent climatology in that height range was identified. This report examines GRAM (MET) constituents between 100 and 1000 km altitudes. Discrepancies are noted between GRAM (MET) constituent number densities and mass density or molecular weight. Near 110 km altitude, there is up to about 25% discrepancy between MET number density and mass density (with mass density being valid and number densities requiring adjustment). Near 700 km altitude there is also up to about 25% discrepancy between MET number density and mean molecular weight (with molecular weight requiring adjustment). In neither case are MET mass density estimates invalidated. These discrepancies have been traced to MET subroutines SLV (which affects 90-170 km height range) and SLVH (which affects helium above 440 km altitude). With these discrepancies corrected, results are presented to illustrate GRAM (MET) constituent mole fractions in terms of height-latitude cross sections from 100 to 1000 km altitude, and latitude-longitude 'maps' at 450 km (approximate height of International Space Station). Plans are discussed for an update of MET (and GRAM) to correct these constituent inconsistencies and to incorporate several new thermospheric model features.

Justus, C. G.↗
DOE OSTI2021

The cardiac molecular setting of metabolic syndrome in pigs reveals disease susceptibility and suggests mechanisms that exacerbate COVID-19 outcomes in patients

Abstract Although metabolic syndrome (MetS) is linked to an elevated risk of cardiovascular disease (CVD), the cardiac-specific risk mechanism is unknown. Obesity, hypertension, and diabetes (all MetS components) are the most common form of CVD and represent risk factors for worse COVID-19 outcomes compared to their non MetS peers. Here, we use obese Yorkshire pigs as a highly relevant animal model of human MetS, where pigs develop the hallmarks of human MetS and reproducibly mimics the myocardial pathophysiology in patients. Myocardium-specific mass spectroscopy-derived metabolomics, proteomics, and transcriptomics enabled the identity and quality of proteins and metabolites to be investigated in the myocardium to greater depth. Myocardium-specific deregulation of pro-inflammatory markers, propensity for arterial thrombosis, and platelet aggregation was revealed by computational analysis of differentially enriched pathways between MetS and control animals. While key components of the complement pathway and the immune response to viruses are under expressed, key N6-methyladenosin RNA methylation enzymes are largely overexpressed in MetS. Blood tests do not capture the entirety of metabolic changes that the myocardium undergoes, making this analysis of greater value than blood component analysis alone. Our findings create data associations to further characterize the MetS myocardium and disease vulnerability, emphasize the need for a multimodal therapeutic approach, and suggests a mechanism for observed worse outcomes in MetS patients with COVID-19 comorbidity.

60 APPLIED LIFE SCIENCES↗
NASA NTRSDate not supplied

EVA Planning: Using Neutral Buoyancy Laboratory (NBL) Training to Predict in-Flight Energy Expenditure

Metabolic rate (“met rate”) is the amount of energy expended over a period of time and is influenced by many factors including body composition, level of physical activity, resting metabolic rate, sex, age, and food intake. Met rate is measured during Extravehicular Activity (EVA) training at the Neutral Buoyancy Laboratory (NBL) and during in-flight EVAs through indirect calorimetry, calculating energy expenditure from respiratory measurements of O 2 consumption and/or CO 2 production. During Extravehicular Activity (EVA) planning, metabolic cost is important to consider and is used to inform EVA duration based on spacesuit consumables associated with life support systems. Currently, NBL and previous ISS EVA met rate data for specified crewmembers are utilized to predict in-flight EVA metabolic costs based on a proposed EVA timeline. Timeline data collected during training is used to relate met rates to specific EVA activities, which are in turn assigned to more generalized EVA task categories, categorizing by both task type and restraint type. EVA task categories include EVA Setup/Cleanup, Worksite Setup/Cleanup, Cable Routing, Bolts, Fluid Connectors, Electrical Connectors, R&R Work, Miscellaneous Work, Incapacitated Crew Rescue (being rescued or performing), Assisted Crew Rescue (being assisted or performing), and Translation. Restraint types consist of Free-Float, Body Restraint Tether (BRT), Articulating Portable Foot Restraint (APFR), and Space Station Remote Manipulator System (SSRMS). From a crewmember’s historical data, individualized 10th, 50th and 90th percentile met rate estimates are generated for each task category and used to estimate the proposed EVA timeline metabolic cost. In-flight metabolic data (“As-Executed”) from recent ISS US EVAs 85-88 (totaling eight EVA crewmember met rates) was compared with their predicted metabolic cost (“As-Planned”) to evaluate the accuracy of the current met rate estimation method. Across the four EVAs, As-Executed Cumulative EVA Total Metabolic Cost (M = 5893.78 BTU, SD = 816.60) was not significantly different compared to As-Planned Cumulative EVA Total Metabolic Cost (M = 6106.60 BTU, SD = 826.62; t(7) = 0.751 , p = .477). Though not a significant difference, generally, As-Planned total estimates were slightly higher than As-Executed total metabolic cost. Relative Error for Cumulative EVA Total Metabolic Cost ranged from -33% to 14.7%, depending on the crewmember and EVA. When comparing As-Planned to A-Executed EVA task categories for Bolts, Electrical Connectors, EVA Cleanup, EVA Setup, Miscellaneous Work, Translation, Worksite Cleanup, and Worksite Setup during these EVAs, no significant differences were observed, however, there was a significant difference in As-Planned (M = 783.71 BTU, SD = 408.88) compared to As-Executed (M = 608.87 BTU, SD = 425.29) metabolic cost for the task category of Repair-and-Replace (R&R) Work (t(17) = 3.21 , p = .005). Looking closer within the R&R Work task category, As-Executed R&R Work with Free-Float restraint type (M = 706.17 BTU, SD = 352.18) was significantly less than As-Planned R&R Work with Free-Float restraint type (M= 887.96 BTU, SD = 381.42; t(12) = 2.59, p < .024). As-Executed R&R Work with SSRMS Restraint type (M = 355.89 BTU, SD = 534.65) was not significantly different from As-Planned values (M = 512.69 BTU, SD = 383.34; t(4) = 1.88, p = 0.132). These findings suggest that the energy expended performing R&R Work (Free-Float) is lower in flight than predicted. Accurate predictions of the metabolic cost of EVA are essential for planning and executing successful ISS EVAs. Overall, the current met rate prediction method is similar to actual in-flight values, slightly erring on the side of overestimation. Future work includes analysis of more historical in-flight EVA data to increase the power of the analysis, evaluating the NBL-ISS met rate conversion factor between NBL and ISS tasks, as well as exploring methods of substitution when crewmembers are missing prior task category data.

Lauren Cox↗
DOE OSTI2025

Automated Redox Titrations via Interdigitated Electrode Arrays: Application to the Mediated Electron Transfer Interrogation of Charge and Rate on Electrodeposited Polymers

Mediated electron transfer (MET) plays a crucial role in energy storage and conversion technologies such as redox targeting flow batteries (RTFBs), yet its experimental investigation often requires labor-intensive and low-throughput setups. To address this, we developed a microfabricated interdigitated electrode array (IDA) platform that enables automated, high-throughput electrochemical redox titration measurement to be performed to study the MET process. Our redox titration method enables simultaneous measurement of the charge capacity and rate of MET processes on a material or surface. Automated redox titration (ART) facilitates systematic investigation of the MET process across a broad parameter space, exemplified through the study of polypyrrole (PPy) and a pyrene-4,5,9,10-tetrone azo group-based polymer (PTAP), both redox-active polymers relevant to various energy storage applications. Using PPy as a model material, 500 redox titration measurements were conducted within 50 h, varying the electrode gap widths, polymer charging potentials, voltammetric scan rates, and electrolyte concentrations. Finite-element simulations confirmed the electrochemical responses and elucidated the kinetics of the MET reactions. Our automated methodology was further tested with PTAP, revealing a surprising charging potential dependence on the rate of MET. The automation, flexibility, and scalability of our redox titration platform pave the way not only for advanced studies of MET processes relevant to RTFBs, but also with implications in the understanding of next-generation energy storage materials, molecular electrocatalysis, and biosensing.

electrochemical analysis↗
DOE OSTI2024

HEU Pancake (Jemima) Plate Preliminary Characterization Report

The HEU pancake (Jemima) plates have been used in multiple International Criticality Safety Benchmark Evaluation Project (ICSBEP) evaluations, including: HEU-MET-FAST-072, HEU-MET-FAST-073, HEU MET-FAST-102, HEU-MET-INTER-006, HEU-MET-INTER-011, HEU-MET-MIXED-021, and IEU MET-FAST-025. This report only focuses on the physical dimension characterization, since concerns have been identified about reliable diameter and height measurements. Historically, height measurements with calipers and mass measurements have been performed for every plate. However, the combination of previous measurements (mass and caliper height measurements) with the drawing dimensions for the diameters led to unrealistic densities (>19 g/cm 3 ) or large ranges of densities for parts that were manufactured at the same time (17 g/cm 3 to >19 g/cm 3 ). Due to the oxidation of the plates, questions about the flatness of each plate and what gaps are introduced into the system have been discussed, since gaps tend to be one of the largest sources of uncertainty in stacked benchmark experiments. The purpose of this report is to characterize a subset of this commonly used fuel. A uniform method for how to define the HEU pancake plates for ICSBEP evaluations will also be proposed with a discussion on what measurements should be performed on the remaining HEU pancake plates in the NCERC inventory.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗
NASA NTRS1994

Coaxial microwave electrothermal thruster performance in hydrogen

The microwave electro thermal thruster (MET) is an electric propulsion concept that offers the promise of high performance combined with a long lifetime. A unique feature of this electric propulsion concept is its ability to create a microwave plasma discharge separated or floating away from any electrodes or enclosing walls. This allows propellant temperatures that are higher than those in resistojets and reduces electrode and wall erosion. It has been demonstrated that microwave energy is coupled into discharges very efficiently at high input power levels. As a result of these advantages, the MET concept has been identified as a future high power electric propulsion possibility. Recently, two additional improvements have been made to the coaxial MET. The first was concerned with improving the microwave matching. Previous experiments were conducted with 10-30 percent reflected power when incident power was in excess of 600 W(exp 6). Power was reflected back to the generator because the impedance of the MET did not match the 50 ohm impedance of the microwave circuit. To solve this problem, a double stub tuning system has been inserted between the MET and the microwave power supply. The addition of the double stub tuners reduces the reflected power below 1 percent. The other improvement has prepared the coaxial MET for hydrogen experiments. To operate with hydrogen, the vacuum window which separates the coaxial line from the discharge chamber has been changed from teflon to boron nitride. All the microwave energy delivered to the plasma discharge passes through this vacuum window. This material change had caused problems in the past because of the increased microwave reflection coefficients associated with the electrical properties of boron nitride. However, by making the boron nitride window electrically one-half of a wavelength long, power reflection in the window has been eliminated. This technical note summarizes the experimental performance of the improved coaxial MET when operating in nitrogen, helium, and hydrogen gases.

Richardson, W.↗
DOE OSTI2022

Core cysteine residues in the Plasminogen-Apple-Nematode (PAN) domain are critical for HGF/c-MET signaling

The Plasminogen-Apple-Nematode (PAN) domain, with a core of four to six cysteine residues, is found in > 28,000 proteins across 959 genera. Still, its role in protein function is not fully understood. The PAN domain was initially characterized in numerous proteins, including HGF. Dysregulation of HGF-mediated signaling results in multiple deadly cancers. The binding of HGF to its cell surface receptor, c-MET, triggers all biological impacts. Here, we show that mutating four core cysteine residues in the HGF PAN domain reduces c-MET interaction, subsequent c-MET autophosphorylation, and phosphorylation of its downstream targets, perinuclear localization, cellular internalization of HGF, and its receptor, c-MET, and c-MET ubiquitination. Furthermore, transcriptional activation of HGF/c-MET signaling-related genes involved in cancer progression, invasion, metastasis, and cell survival were impaired. Thus, targeting the PAN domain of HGF may represent a mechanism for selectively regulating the binding and activation of the c-MET pathway.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2021

Nuclear Data and Cross Section Testing Using ENDF/B-VIII.0

With the release of the Evaluated Nuclear Data File (ENDF)/B-VIII.0 library, nuclear criticality safety practitioners and engineers have access to the latest cross section sets available for their analyses. However, these cross sections must be rigorously tested and validated to ensure that the nuclear data are responsive to the needs of the individuals responsible for developing, implementing, and maintaining computational tools for criticality safety applications. Thus, the ENDF/B-VIII.0 library is tested and validated with a large collection of experiments that were vetted by the International Criticality Safety Benchmark Evaluation Project and made available in the International Handbook of Evaluated Criticality Safety Benchmark Experiments. A selection of benchmark experiments for use within the criticality safety community were prepared and reviewed within the Verified, Archived Library of Inputs and Data (VALID), which is maintained by the Nuclear Energy and Fuel Cycle Division at Oak Ridge National Laboratory. The performance of the ENDF/B-VIII.0 library is assessed by using VALID models of benchmark experiments with the beta 12 version of SCALE 6.3 KENO V.a and KENO-VI Monte Carlo codes. The performance is compared with the results obtained from with the ENDF/B-VII.1 library. This report considers multigroup (MG) and continuous energy (CE) formats of the ENDF/B-VIII.0 and -VII.1 libraries. The benchmark experiments within VALID that validate the ENDF/B-VIII.0 library cover 15 broad system categories by using a range of fissile materials, uranium enrichments, plutonium isotopic vectors, and mixed uranium/plutonium systems. These forms are represented as metals, solutions, or various arrays of rods or plates that cover a variety of neutron energy spectra: thermal, fast, mixed, and intermediate. Over 600 cases were considered for use with the KENO V.a and KENO-VI codes with the ENDF/B-VIII.0 library. The results of the Monte Carlo comparison of ENDF/B-VIII.0 to ENDF/B-VII.1 with both KENO V.a and KENO-VI indicate that there is a less than 0.53% Δk difference between the bias of calculated k eff from the expected values. The CE ENDF/B-VIII.0 library results in smaller magnitude biases than the ENDF/B-VII.1 data for HEU-MET-FAST, HEU-SOL-THERM, IEU-MET-FAST, LEU-SOL-THERM, PU-SOL-THERM, and U233-MET-FAST systems, while the MG results yielded smaller magnitude biases for HEU-MET-FAST, HEU-SOL-THERM, IEU-MET-FAST, LEU-COMP-THERM, LEU-SOL THERM, MIX-COMP-FAST, and U233-MET-FAST systems. Most notable are the adjustments to the plutonium and 233 U cross section data, which has resulted in noticeably lower biases in the ENDF/B VIII.0 results for the mixed, plutonium, and 233 U systems. Results of the sensitivity data file comparison generated from TSUNAMI-3D for selected VALID cases for the ENDF/B-VIII.0 library indicate a very high level of agreement with correlation coefficients of the effect of nuclear data uncertainty on k eff (the c k integral parameter) all above 0.99. This indicates that cases with the ENDF/B-VIII.0 library would see very similar responses to any nuclear data errors or change as those with the ENDF/B-VII.1 library.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗
NASA NTRS1992

Microwave Electrothermal Propulsion for Space

The microwave electrothermal thruster (MET) concept for medium or high-power spacecraft propulsion is described. The MET employs continuous wave microwave energy to create and maintain a plasma discharge in a flowing propellant gas. The discharge then acts to absorb the applied microwave energy and transform it into thermal and internal energy of the propellant. Expansion and expulsion of the hot propellant through a throat and nozzle finally converts the energy of the gas into thrust. The MET concept is electrodeless, synergistically combines high pressure and high power capability, provides external control over the energy-conversion discharge, and operates on hydrogen propellant. The potential performance of the MET on hydrogen propellant has been modeled with a two-dimensional kinetics computer code. The MET concept is particularly suitable for use with a magnetic nozzle. Apparatus is described for testing the resonant-cavity MET to power levels of 30 kW at 915 MHz on nitrogen, helium, and hydrogen. The low-ripple operation of the microwave generator has been verified, as has a procedure for starting the microwave discharge and raising the power applied to the cavity via a phase shifter-tuner.

Power, John L.↗