Engineering Papers⌕ Search

SEARCH · Engineering Papers

Results for “dead time”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 91 records · Page 5

NASA Tech Briefs, June 2004

Topics covered include: COTS MEMS Flow-Measurement Probes; Measurement of an Evaporating Drop on a Reflective Substrate; Airplane Ice Detector Based on a Microwave Transmission Line; Microwave/Sonic Apparatus Measures Flow and Density in Pipe; Reducing Errors by Use of Redundancy in Gravity Measurements; Membrane-Based Water Evaporator for a Space Suit; Compact Microscope Imaging System with Intelligent Controls; Chirped-Superlattice, Blocked-Intersubband QWIP; Charge-Dissipative Electrical Cables; Deep-Sea Video Cameras Without Pressure Housings; RFID and Memory Devices Fabricated Integrally on Substrates; Analyzing Dynamics of Cooperating Spacecraft; Spacecraft Attitude Maneuver Planning Using Genetic Algorithms; Forensic Analysis of Compromised Computers; Document Concurrence System; Managing an Archive of Images; MPT Prediction of Aircraft-Engine Fan Noise; Improving Control of Two Motor Controllers; Electro-deionization Using Micro-separated Bipolar Membranes; Safer Electrolytes for Lithium-Ion Cells; Rotating Reverse-Osmosis for Water Purification; Making Precise Resonators for Mesoscale Vibratory Gyroscopes; Robotic End Effectors for Hard-Rock Climbing; Improved Nutation Damper for a Spin-Stabilized Spacecraft; Exhaust Nozzle for a Multitube Detonative Combustion Engine; Arc-Second Pointer for Balloon-Borne Astronomical Instrument; Compact, Automated Centrifugal Slide-Staining System; Two-Armed, Mobile, Sensate Research Robot; Compensating for Effects of Humidity on Electronic Noses; Brush/Fin Thermal Interfaces; Multispectral Scanner for Monitoring Plants; Coding for Communication Channels with Dead-Time Constraints; System for Better Spacing of Airplanes En Route; Algorithm for Training a Recurrent Multilayer Perceptron; Orbiter Interface Unit and Early Communication System; White-Light Nulling Interferometers for Detecting Planets; and Development of Methodology for Programming Autonomous Agents.

Source record↗

Performance Considerations for the SIMPL Single Photon, Polarimetric, Two-Color Laser Altimeter as Applied to Measurements of Forest Canopy Structure and Composition

The Slope Imaging Multi-polarization Photon-counting Lidar (SIMPL) is a multi-beam, micropulse airborne laser altimeter that acquires active and passive polarimetric optical remote sensing measurements at visible and near-infrared wavelengths. SIMPL was developed to demonstrate advanced measurement approaches of potential benefit for improved, more efficient spaceflight laser altimeter missions. SIMPL data have been acquired for wide diversity of forest types in the summers of 2010 and 2011 in order to assess the potential of its novel capabilities for characterization of vegetation structure and composition. On each of its four beams SIMPL provides highly-resolved measurements of forest canopy structure by detecting single-photons with 15 cm ranging precision using a narrow-beam system operating at a laser repetition rate of 11 kHz. Associated with that ranging data SIMPL provides eight amplitude parameters per beam unlike the single amplitude provided by typical laser altimeters. Those eight parameters are received energy that is parallel and perpendicular to that of the plane-polarized transmit pulse at 532 nm (green) and 1064 nm (near IR), for both the active laser backscatter retro-reflectance and the passive solar bi-directional reflectance. This poster presentation will cover the instrument architecture and highlight the performance of the SIMPL instrument with examples taken from measurements for several sites with distinct canopy structures and compositions. Specific performance areas such as probability of detection, after pulsing, and dead time, will be highlighted and addressed, along with examples of their impact on the measurements and how they limit the ability to accurately model and recover the canopy properties. To assess the sensitivity of SIMPL's measurements to canopy properties an instrument model has been implemented in the FLIGHT radiative transfer code, based on Monte Carlo simulation of photon transport. SIMPL data collected in 2010 over the Smithsonian Environmental Research Center, MD are currently being modelled and compared to other remote sensing and in situ data sets. Results on the adaptation of FLIGHT to model micropulse, single'photon ranging measurements are presented elsewhere at this conference. NASA's ICESat-2 spaceflight mission, scheduled for launch in 2016, will utilize a multi-beam, micropulse, single-photon ranging measurement approach (although non-polarimetric and only at 532 nm). Insights gained from the analysis and modelling of SIMPL data will help guide preparations for that mission, including development of calibration/validation plans and algorithms for the estimation of forest biophysical parameters.

Dabney, Philip W.↗

Single-Photon-Sensitive HgCdTe Avalanche Photodiode Detector

The purpose of this program was to develop single-photon-sensitive short-wavelength infrared (SWIR) and mid-wavelength infrared (MWIR) avalanche photodiode (APD) receivers based on linear-mode HgCdTe APDs, for application by NASA in light detection and ranging (lidar) sensors. Linear-mode photon-counting APDs are desired for lidar because they have a shorter pixel dead time than Geiger APDs, and can detect sequential pulse returns from multiple objects that are closely spaced in range. Linear-mode APDs can also measure photon number, which Geiger APDs cannot, adding an extra dimension to lidar scene data for multi-photon returns. High-gain APDs with low multiplication noise are required for efficient linear-mode detection of single photons because of APD gain statistics -- a low-excess-noise APD will generate detectible current pulses from single photon input at a much higher rate of occurrence than will a noisy APD operated at the same average gain. MWIR and LWIR electron-avalanche HgCdTe APDs have been shown to operate in linear mode at high average avalanche gain (M > 1000) without excess multiplication noise (F = 1), and are therefore very good candidates for linear-mode photon counting. However, detectors fashioned from these narrow-bandgap alloys require aggressive cooling to control thermal dark current. Wider-bandgap SWIR HgCdTe APDs were investigated in this program as a strategy to reduce detector cooling requirements.

Huntington, Andrew↗

High Frequency Design Considerations for the Large Detector Number and Small Form Factor Dual Electron Spectrometer of the Fast Plasma Investigation on NASA's Magnetospheric Multiscale Mission

Each half of the Dual Electron Spectrometer (DES) of the Fast Plasma Investigation (FPI) on NASA's Magnetospheric MultiScale (MMS) mission utilizes a microchannel plate Chevron stack feeding 16 separate detection channels each with a dedicated anode and amplifier/discriminator chip. The desire to detect events on a single channel with a temporal spacing of 100 ns and a fixed dead-time drove our decision to use an amplifier/discriminator with a very fast (GHz class) front end. Since the inherent frequency response of each pulse in the output of the DES microchannel plate system also has frequency components above a GHz, this produced a number of design constraints not normally expected in electronic systems operating at peak speeds of 10 MHz. Additional constraints are imposed by the geometry of the instrument requiring all 16 channels along with each anode and amplifier/discriminator to be packaged in a relatively small space. We developed an electrical model for board level interactions between the detector channels to allow us to design a board topology which gave us the best detection sensitivity and lowest channel to channel crosstalk. The amplifier/discriminator output was designed to prevent the outputs from one channel from producing triggers on the inputs of other channels. A number of Radio Frequency design techniques were then applied to prevent signals from other subsystems (e.g. the high voltage power supply, command and data handling board, and Ultraviolet stimulation for the MCP) from generating false events. These techniques enabled us to operate the board at its highest sensitivity when operated in isolation and at very high sensitivity when placed into the overall system.

Microchannel plates high frequency performance↗

Study of Static Microchannel Plate Saturation Effects for the Fast Plasma Investigation Dual Electron Spectrometers on NASA's Magnetospheric MultiScale Mission

Imaging detecting systems based on microchannel plates (MCPs) are the most common for low energy plasma measurements for both space borne and ground applications. One of the key parameters of these detection systems is the dynamic range of the MCP's response to the input fluxes of charged particles. For most applications the dynamic range of the linear response should be as wide as possible. This is especially true for the Dual Electron Spectrometers (DESs) of the Fast Plasma Investigation (FPI) on NASA's Magnetospheric MultiScale (MMS) mission because a wide range of input fluxes are expected. To make use of the full available dynamic range, it is important to understand the MCP response behavior beyond the linear regime where the MCPs start to saturate. We have performed extensive studies of this during the characterization and calibration of the DES instruments and have identified several saturation effects of the detection system. The MCP itself exhibits saturation when the channels lack the ability to replenish charge sufficiently rapidly. It is found and will be shown that the ground system can significantly impact the correct measurement of this effect. As the MCP starts to saturate, the resulting pulse height distribution (PHD) changes shape and location (with less pulse height values), which leads to truncation of the PHD by the threshold set on the detection system discriminator. Finally, the detection system pulse amplifier exhibits saturation as the input flux drives pulse rates greater than its linear response speed. All of these effects effectively change the dead time of the overall detection system and as a result can affect the quality and interpretation of the flight data. We present results of detection system saturation effects and their interaction with special emphasis on the MCP related effects.

detecting system↗

HgCdTe e-APD Detector Arrays with Single Photon Sensitivity for Space Lidar Applications

A multi-element HgCdTe electron initiated avalanche photodiode (e-APD) array has been developed for space lidar applications. The detector array was fabricated with 4.3-μm cutoff HgCdTe which covered a spectral response from 0.4 to 4.3 μm. We have characterized a 4x4 detector array with 80 μm square elements and an integrated custom cryogenic silicon read-out integrated circuit (ROIC). The device operated at 77K inside a small closed-cycle Dewar. Measurements showed a unity gain quantum efficiency of about 90% at 1.55 μm. The bulk dark current of the HgCdTe e-APD at 77K was less than 50,000 input referred electrons/s at 12 V APD bias where the APD gain was 620 and the measured noise equivalent power (NEP) was 0.4 fW/Hz1/2. The electrical bandwidth of the ROIC was about 6 MHz, which was chosen to match the laser pulse width of our CO2 lidar. Even with the relatively low bandwidth, the high APD gain and low dark current enabled the device to detect single photon events. Because the APD was biased below the break-down voltage, the detector output was linear with the input optical signal and there was no dead-time and afterpulsing. A new series of HgCdTe e-APDs are being developed with a much wider bandwidth ROIC and higher gain HgCdTe e-APD array, which is expected to give a much better performance in linear mode photon counting applications.

HgCdTe↗

Mapping of Spacecraft Atmosphere Monitor Signal to Major Constituent Abundances

The Spacecraft Atmosphere Monitor (S.A.M.) follows the JPL’s commitment to introduce and develop next-generation instrumentation concepts for sensing the air quality on manned space flights via continuous sampling, measuring, and reporting in 2s intervals on all gaseous pollutants. The S.A.M. will have two modes of operation: the Major Constituent Analysis (MCA) mode and the Trace Gas Analysis (TGA) mode. The MCA mode will report on molecular analytes such as CH4, H2O, N2, O2, Ar, and CO2 while the TGA mode will acquire minute amounts of volatile organic compounds. Both modes assess the composition of the ambient air with twenty full mass spectra per second giving rise to a substantial amount of data to be processed by a set of small footprint software stacks hosted by an on-board computer. Mass spectra will be accumulated as the number of counts recorded in a given mass-to-charge channel and converted into the absolute abundances of detected species using an efficient algorithm. The decomposition algorithm contains four units: peak identification, mass calibration, background and dead time correction, and an abundance analysis unit. The abundance analysis module identifies target species through their characteristic fragmentation patterns in the presence of molecular isobars, such as CO and N2. For example, in order to identify N2 analyte, the code will simultaneously monitor abundance ratios of the 14, 28 and 29 Th signals and will adapt to any instability caused by a decrease in ambient pressure or changes in humidity. This requirement becomes critical for instruments designed to monitor the near real-time quality of cabin air and promptly provide accurate feedbacks.

Nikolic, D.↗

ICESat-2/ATLAS at 4 Years: Instrument Performance and Projected Life

NASA’s ICESat-2 mission launched in September 2018 carrying a single instrument, the Advanced Topographic Laser Altimeter System (ATLAS). ATLAS uses a high-repetition-rate, low-pulse-energy laser with its output split into six beams and a photon-counting receiver to measure Earth surface elevation with centimeter-level precision, repeating its ground track every 91 days. During more than four years of on-orbit operation, ATLAS has met or exceeded its lifetime and performance requirements. We present performance measurements, trends and projections for several instrument parameter, including transmitted laser pulse energy, receiver sensitivity, the instrument’s impulse response, transmitter/receiver alignment, dead-time behavior, and elevation measurement performance. The laser energy setting was increased in September 2023, for the first time, to maintain ranging performance at its early mission level. The trends in instrument parameters indicate capability to continue on-orbit operation of ATLAS for many years into the future.

Anthony J. Martino↗

Finding the global minimum: a fuzzy end elimination implementation

The 'fuzzy end elimination theorem' (FEE) is a mathematically proven theorem that identifies rotameric states in proteins which are incompatible with the global minimum energy conformation. While implementing the FEE we noticed two different aspects that directly affected the final results at convergence. First, the identification of a single dead-ending rotameric state can trigger a 'domino effect' that initiates the identification of additional rotameric states which become dead-ending. A recursive check for dead-ending rotameric states is therefore necessary every time a dead-ending rotameric state is identified. It is shown that, if the recursive check is omitted, it is possible to miss the identification of some dead-ending rotameric states causing a premature termination of the elimination process. Second, we examined the effects of removing dead-ending rotameric states from further considerations at different moments of time. Two different methods of rotameric state removal were examined for an order dependence. In one case, each rotamer found to be incompatible with the global minimum energy conformation was removed immediately following its identification. In the other, dead-ending rotamers were marked for deletion but retained during the search, so that they influenced the evaluation of other rotameric states. When the search was completed, all marked rotamers were removed simultaneously. In addition, to expand further the usefulness of the FEE, a novel method is presented that allows for further reduction in the remaining set of conformations at the FEE convergence. In this method, called a tree-based search, each dead-ending pair of rotamers which does not lead to the direct removal of either rotameric state is used to reduce significantly the number of remaining conformations. In the future this method can also be expanded to triplet and quadruplet sets of rotameric states. We tested our implementation of the FEE by exhaustively searching ten protein segments and found that the FEE identified the global minimum every time. For each segment, the global minimum was exhaustively searched in two different environments: (i) the segments were extracted from the protein and exhaustively searched in the absence of the surrounding residues; (ii) the segments were exhaustively searched in the presence of the remaining residues fixed at crystal structure conformations. We also evaluated the performance of the method for accurately predicting side chain conformations. We examined the influence of factors such as type and accuracy of backbone template used, and the restrictions imposed by the choice of potential function, parameterization and rotamer database. Conclusions are drawn on these results and future prospects are given.

NASA Program Exobiology↗

The Effect of Beam Loading on Water Impact Loads and Motions

An investigation of the effect of beam loading on impact loads and motions has been conducted in the Langley impact basin. Water impact tests of flat-bottom 5-inch- and 8-inch-beam models having beam-loading coefficients C(sub Delta) from 62.5 to 544 and a 30 0 dead-rise 5-inch-beam model A having beam-loading coefficients from 208 to 530 are described and the results analyzed to show trends of these heavy-beam-loading data with initial flight-path angle, trim angle, dead-rise angle, and time throughout the impact. Data from flat-bottom model tests, C(sub Delta) = 4.4 to 36.5, and from 300 dead-rise model tests, C(sub Delta)A = 0.58 and 18.8, are included, along with the heavy-beam-loading data; and variations of these data with beam-loading coefficients are shown. Each of the load and motion coefficients is found to be directly proportional to a power factor ofC(sub Delta). For instance, the maximum impact lift coefficient C(sub L,max)is found to be directly proportional to C(sub Delta)(sup 0.33) for the flat-bottom model and C(sub Delta)(sup 0.45) for the 30 deg dead-rise model. These variations of C(sub L,max) C(sub Delta) are found to be in agreement with theoretical variations. Finally, an empirical equation for the prediction of C(sub L,max) is presented and is shown to give good agreement with experimental C(sub L,max) for about 500 fixed-trim smooth-water impacts. The range of variables included dead-rise angles from 0 deg to 30 deg, beam-loading coefficients from 0.48 to 544, trim angles from 3 deg to 45 deg and initial flight-path angles from about 2 deg to about 27 deg.

Mixson, John S.↗

The Effect of Beam Loading on Water Impact Loads and Motions

An investigation of the effect of beam loading on impact loads and motions has been conducted in the Langley impact basin. Water impact tests of flat-bottom 5-inch-and 8-inch-beam models having beam-loading coefficients C(sub Delta) from 62.5 to 544 and a 30 deg dead-rise 5-inch-beam model A having beam-loading coefficients from 208 to 530 are described and the results analyzed to show trends of these heavy-beam-loading data with initial flight-path angle, trim angle, dead-rise angle, and time through- out the impact. Data from flat-bottom model tests, C(sub Delta) = 4.4 to 36.5, and from 30 deg dead-rise model tests, C(sub Delta) = 0.58 and 18.8, are included, along with the heavy-beam-loading data; and variations of these data with beam-loading coefficients are shown. Each of the load and motion coefficients is found to be directly proportional to a power factor of C(sub Delta). For instance, the maximum impact lift coefficient is found C(sub L,max) to be directly proportional to C(sub Delta, exp 0,33) for the flat-bottom model and C(sub Delta, exp 0,45) for the 30 deg dead-rise model. These variations of C(sub L, max) with C(sub Delta) are found to be in agreement with theoretical variations. Finally, an empirical equation for the prediction of C(sub L,max) is presented and is shown to give good agreement with experimental C(sub L, max) for about 500 fixed-trim smooth-water impacts. The range of variables included dead-rise angles from 0 deg to deg, beam-loading coefficients from o.48 to 544, trim angles from 3 deg to deg, and initial flight-path angles from about 2 deg to about deg.

Mixson, John S.↗

Interactive LORAN-C to geographic and geographic-to-LORAN-C computation

The LORAN program is stored in CMS disk files for use by Avionics Engineering Center terminal users. A CMS EXEC file named LORAN controls program operation. The user types LORAN and the program then prompts for data input and produces output on the terminal. The FORTRAN program refers to a disk file of LORAN master data giving station locations, coding delays, repetition rate and station pair identification letters. For Geographic-to-LORAN conversion, no iterative computations are required; the program is a straightforward coordinate conversion based upon the techniques described by the Navy. For LORAN-to-Geographic conversion, the original Navy program required a dead-reckoned position, near the actual unknown fix, to begin computations. No iteration was performed to obtain the LORAN fix, but internal program errors occurred at execution time if the dead-reckoned fix were displaced from the actual fix by more than a few minutes of latitude or longitude. In order to enhance usefulness of the program for the terminal user, an iterative routine was added which allows a single dead-reckoned position to be entered from the master data file for each LORAN chain. The results compare exactly with the LORAN-C navigation chart, and provide adequate benchmark data for general aviation flight planning and data analysis.

Piecuch, L. M.↗

Predicted Performance of On-Off Systems for Precise Satellite Attitude Control

An investigation has been made of the use of on-off reaction jets for precision attitude control of a satellite. Since a symmetrical vehicle is assumed, only single-axis control needs to be considered. The responses to initial disturbances and also limit-cycle characteristics for several systems have been evaluated. Calculated results indicate that realistic values of settling time and fuel consumption for the example considered can be obtained. The performance of a given system depends on the characteristics of the error detector used. In cases where the detector output was saturated for a relatively low error input, the settling time deteriorated when a lead network was used to provide damping. This deterioration could be eliminated if a separate rate signal to produce vehicle rate limiting were available. As an alternate approach, two systems were investigated which used a timed sequence of torques and could operate with a detector output of very small linear range. Although the performance of these systems was poorer than that of the lead network system without detector saturation, the performance was better than that of the lead network system with low values of detector saturation. The effects on limit-cycle characteristics of hysteresis, lead network constants, dead zone, and thrust time delays were also investigated.

Brown, Stuart C.↗

The Effects of Longitudinal Control-System Dynamics on Pilot Opinion and Response Characteristics as Determined from Flight Tests and from Ground Simulator Studies

The results of a fixed-base simulator study of the effects of variable longitudinal control-system dynamics on pilot opinion are presented and compared with flight-test data. The control-system variables considered in this investigation included stick force per g, time constant, and dead-band, or stabilizer breakout force. In general, the fairly good correlation between flight and simulator results for two pilots demonstrates the validity of fixed-base simulator studies which are designed to complement and supplement flight studies and serve as a guide in control-system preliminary design. However, in the investigation of certain problem areas (e.g., sensitive control-system configurations associated with pilot- induced oscillations in flight), fixed-base simulator results did not predict the occurrence of an instability, although the pilots noted the system was extremely sensitive and unsatisfactory. If it is desired to predict pilot-induced-oscillation tendencies, tests in moving-base simulators may be required. It was found possible to represent the human pilot by a linear pilot analog for the tracking task assumed in the present study. The criterion used to adjust the pilot analog was the root-mean-square tracking error of one of the human pilots on the fixed-base simulator. Matching the tracking error of the pilot analog to that of the human pilot gave an approximation to the variation of human-pilot behavior over a range of control-system dynamics. Results of the pilot-analog study indicated that both for optimized control-system dynamics (for poor airplane dynamics) and for a region of good airplane dynamics, the pilot response characteristics are approximately the same.

Sadoff, Melvin↗

Estimation of coarse dead wood stocks in intact and degraded forests in the Brazilian Amazon using airborne lidar

Coarse dead wood is an important component of forest carbon stocks, but it is rarely measured in Amazon forests and is typically excluded from regional forest carbon budgets. Our study is based on line intercept sampling for fallen coarse dead wood conducted along 103 transects with a total length of 48 km matched with forest inventory plots where standing coarse dead wood was measured in the footprints of larger areas of airborne lidar acquisitions. We developed models to relate lidar metrics and Landsat time series variables to coarse dead wood stocks for intact, logged, burned, or logged and burned forests. Canopy characteristics such as gap area produced significant individual relations for logged forests. For total fallen plus standing coarse dead wood (hereafter defined as total coarse dead wood), the relative root mean square error for models with only lidar metrics ranged from 33 % in logged forest to up to 36 % in burned forests. The addition of historical information improved model performance slightly for intact forests (31 % against 35 % relative root mean square error), not justifying the use of a number of disturbance events from historical satellite images (Landsat) with airborne lidar data. Lidar-derived estimates of total coarse dead wood compared favorably with independent ground-based sampling for areas up to several hundred hectares. The relations found between total coarse dead wood and variables quantifying forest structure derived from airborne lidar highlight the opportunity to quantify this important but rarely measured component of forest carbon over large areas in tropical forests.

Brazilian Amazon↗

RTSJ Memory Areas and Their Affects on the Performance of a Flight-Like Attitude Control System

The two most important factors in improving performance in any software system, but especially a real-time, embedded system, are knowing which components are the low performers and knowing what can be done to improve their performance. The word performance with respect to a real-time, embedded system does not necessarily mean fast execution, which is the common definition when discussing non real-time systems. It also includes meeting all of the specified execution dead-lines and executing at the correct time without sacrificing non real-time performance. Using a Java prototype of an existing control system used on Deep Space 1[1], the effects from adding memory areas are measured and evaluated with respect to improving performance.

Real-time Specification for Java2 (RTSJ)↗

Immunity-Based Aircraft Fault Detection System

In the study reported in this paper, we have developed and applied an Artificial Immune System (AIS) algorithm for aircraft fault detection, as an extension to a previous work on intelligent flight control (IFC). Though the prior studies had established the benefits of IFC, one area of weakness that needed to be strengthened was the control dead band induced by commanding a failed surface. Since the IFC approach uses fault accommodation with no detection, the dead band, although it reduces over time due to learning, is present and causes degradation in handling qualities. If the failure can be identified, this dead band can be further A ed to ensure rapid fault accommodation and better handling qualities. The paper describes the application of an immunity-based approach that can detect a broad spectrum of known and unforeseen failures. The approach incorporates the knowledge of the normal operational behavior of the aircraft from sensory data, and probabilistically generates a set of pattern detectors that can detect any abnormalities (including faults) in the behavior pattern indicating unsafe in-flight operation. We developed a tool called MILD (Multi-level Immune Learning Detection) based on a real-valued negative selection algorithm that can generate a small number of specialized detectors (as signatures of known failure conditions) and a larger set of generalized detectors for unknown (or possible) fault conditions. Once the fault is detected and identified, an adaptive control system would use this detection information to stabilize the aircraft by utilizing available resources (control surfaces). We experimented with data sets collected under normal and various simulated failure conditions using a piloted motion-base simulation facility. The reported results are from a collection of test cases that reflect the performance of the proposed immunity-based fault detection algorithm.

Dasgupta, D.↗

Effects of inspired CO2, hyperventilation, and time on VA/Q inequality in the dog

In a recent study by Tsukimoto et al. (J. Appl. Physiol. 68: 2488-2493, 1990), CO2 inhalation appeared to reduce the size of the high ventilation-perfusion ratio (VA/Q) mode commonly observed in anesthetized mechanically air-ventilated dogs. In that study, large tidal volumes (VT) were used during CO2 inhalation to preserve normocapnia. To separate the influences of CO2 and high VT on the VA/Q distribution in the present study, we examined the effect of inspired CO2 on the high VA/Q mode using eight mechanically ventilated dogs (4 given CO2, 4 controls). The VA/Q distribution was measured first with normal VT and then with increased VT. In the CO2 group at high VT, data were collected before, during, and after CO2 inhalation. With normal VT, there was no difference in the size of the high VA/Q mode between groups [10.5 +/- 3.5% (SE) of ventilation in the CO2 group, 11.8 +/- 5.2% in the control group]. Unexpectedly, the size of the high VA/Q mode decreased similarly in both groups over time, independently of the inspired PCO2, at a rate similar to the fall in cardiac output over time. The reduction in the high VA/Q mode together with a simultaneous increase in alveolar dead space (estimated by the difference between inert gas dead space and Fowler dead space) suggests that poorly perfused high VA/Q areas became unperfused over time. A possible mechanism is that elevated alveolar pressure and decreased cardiac output eliminate blood flow from corner vessels in nondependent high VA/Q regions.

NASA Discipline Cardiopulmonary↗