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This commentary outlines how magnetic resonance imaging (MRI) microscopy studies of prostate tissue samples and whole organs have shed light on a number of clinical imaging mysteries and may enable more effective development of new clinical imaging methods.
Magnesium and its alloys are being investigated widely for applications that require extraordinarily high strength-to-weight ratio, vibration damping, electromagnetic shielding, reduction in carbon footprint, sustainability improvements, and low toxicity. In the past decade or so, this drive has led to increased adoption of magnesium and its alloys in everyday products and it is no longer regarded as an esoteric material. The overarching goal of its widespread adoption and replacement of conventional materials such as steel and aluminum alloys has been restricted due to the cost of the material, limited sources of primary material, alloying constraints, high chemical reactivity, and challenges associated with its plasticity. Researchers/scientists, engineers, and economists from industry, government agencies/laboratories, and academic institutions alike are actively developing roadmaps for next-generation products and addressing these challenges as quickly as possible through unique and innovative methods. The TMS Magnesium Committee has been actively involved in providing a platform to these entities for disseminating the latest information, developments, and cutting-edge research and development, and showcasing the latest trends related to magnesium and its alloys through the Magnesium Technology Symposium, which takes place every year at the annual TMS conference. This proceedings edition/volume retains the essence of this long-standing tradition. The 20th volume, Magnesium Technology 2019, is the proceedings of the Magnesium Technology Symposium held during the 148th TMS Annual Meeting & Exhibition in San Antonio, Texas, March 10–14, 2019. This proceeding captures commentaries and papers from 16 different nations who presented their work; the papers have been categorized systematically, based on topics pertaining to casting and solidification, thermomechanical processing, deformation mechanisms, modeling, corrosion, recycling, and applications.
Magnesium and its alloys are being investigated widely for applications that require extraordinarily high strength-to-weight ratio, vibration damping, electromagnetic shielding, reduction in carbon footprint, sustainability improvements, and low toxicity. In the past decade or so, this drive has led to increased adoption of magnesium and its alloys in everyday products and it is no longer regarded as an esoteric material. The overarching goal of its widespread adoption and replacement of conventional materials such as steel and aluminum alloys has been restricted because of the cost of the material, limited sources of primary material, alloying constraints, high chemical reactivity, and challenges associated with its plasticity. Researchers, scientists, engineers, and economists from industry, government agencies and laboratories, and academic institutions alike are actively developing roadmaps for next-generation products and addressing these challenges as quickly as possible through unique and innovative methods. The TMS Magnesium Committee has been actively involved in providing a platform to these entities for disseminating the latest information, developments, and cutting-edge research and development, and showcasing the latest research and development trends related to magnesium and its alloys through the Magnesium Technology Symposium, which takes place every year at the TMS Annual Meeting. This proceedings volume retains the essence of this longstanding tradition. The twenty-first volume in the series, Magnesium Technology 2020, is the proceedings of the Magnesium Technology Symposium held during the 149th TMS Annual Meeting & Exhibition in San Diego, CA, February 23–27, 2020. The volume captures commentaries and papers from 15 different countries. The papers have been categorized systematically based on topics pertaining to magnesium production, casting and solidification, thermomechanical processing, deformation mechanisms, modeling, corrosion, and applications. The symposium began with keynote sessions that featured several distinguished invited speakers from government organizations and academia, who provided their perspectives on the state of the art, goals, and opportunities in magnesium alloy research and development. Dr. Carlos Tomé from Los Alamos National Laboratory, U.S. Department of Energy, discussed 3D characterization of mechanical twins across grain boundaries. This was followed by a talk on hierarchically structured ultrafine-grained magnesium alloys by Dr. Rajiv Mishra from the University of North Texas, USA, who presented an example of using friction stir additive manufacturing for implementing such microstructures at a component level. Dr. Mark Horstemeyer from Liberty University, USA, presented an overview of fatigue modeling to capture the corrosion-fatigue behavior of magnesium alloys. The final talk in this session was presented by Dr. Bin Jiang from Chongqing University, China, who presented a novel extrusion approach for achieving high-strength magnesium alloy plates.
Cascading hazards are becoming more prevalent in the central Himalayas. Primary hazards (e.g., earthquakes, avalanches, and landslides) often trigger secondary hazards (e.g., landslide dam, debris flow, and flooding), compounding the risks to human settlements, infrastructures, and ecosystems. Risk management strategies are commonly tailored to a single hazard, leaving human and natural systems vulnerable to cascading hazards. In this commentary, we characterize diverse natural hazards in the central Himalayas, including their cascading mechanisms and potential impacts. A scientifically sound understanding of the cascading hazards, underlying mechanisms, and appropriate tools to account for the compounding risks are crucial to informing the design of risk management strategies. Here, we also discuss the need for an integrated modeling framework, reliable prediction and early warning system, and sustainable disaster mitigation and adaptation strategies.
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Invited editorial commentary article on Atom Probe Tomography.
A paper by Foglio Bonda et al. published previously in this journal (2016, Vol. 83, pp. 175–183) discussed the use of mixture experiment design and modeling methods to study how the proportions of three components in an extemporaneous oral suspension affected the mean diameter of drug particles (Z ave ). The three components were itraconazole (ITZ), Tween 20 (TW20), and Methocel® E5 (E5). This commentary addresses some errors and other issues in the previous paper, and also discusses an improved model relating proportions of ITZ, TW20, and E5 to Z ave . The improved model contains six of the 10 terms in the full-cubic mixture model, which were selected using a different cross-validation procedure than used in the previous paper. In conclusion, compared to the four-term model presented in the previous paper, the improved model fit the data better, had excellent cross-validation performance, and the predicted Z ave of a validation point was within model uncertainty of the measured value.
Sociotechnical imaginaries emerged in the last decade as a potentially fruitful approach to understanding how collective social values inflect on the production of scientific knowledge and the design of technological systems. Yet insights generated to date have focused on the categories experts use to define a society’s idealized organization, either as the direct subject of analysis by documentary analysis or through the ways such categories circumscribe the field of authorized “values” open for adjudication in public engagement events. We argue that sociotechnical imaginaries require a new methodological framework for designing research in order to examine the collective values of citizens as they live their daily lives, rather than focusing on experts and the state in order to understand the shared moral, material, and scientific goals of a society. Drawing inspiration from rhetoric, corpus linguistics, and dialectology, we present the Social Energy Atlas, a new and burgeoning research project that employs such methods for studying emergent narrative patterns and variation at the local level. Furthermore, advancing the theory and practice of studying sociotechnical imaginaries is of tremendous benefit to Energy and Social Science researchers, and it is our intent this commentary encourages further careful development and use of the concept.
Here, to date, in the absence of a technology-agnostic national decarbonization policy, technology-specific policies have driven US grid decarbonization, and solar deployment in particular. Many of these technology policies are now ending, leaving low prices and market forces to drive future solar deployment. However, low prices and market forces alone are not likely to achieve the pace and scale of solar deployment required to meet US decarbonization targets. Here, we draw fresh insights from the recently published US Department of Energy's Solar Futures Study - led by the authors of this commentary - to show that policy-supported solar innovation and deployment remain critical for grid decarbonization in the United States.
Here, in this Commentary, we aim to clarify the relationship between electricity demand and prices in the short- and longer-term. We outline three dimensions that shape this relationship: system capacity utilization, system expansion costs, and cost allocation in the rate design process. We explain why demand growth has historically been largely associated with falling electricity prices and explore arguments that future C&I demand growth may increase prices.
This is a brief commentary paper to highlight and discuss the determination of hydrogen concentration in pipeline steel, effect of hydrogen embrittlement (HE) on the mechanical properties of the material, burst strength of corroded pipelines using finite element analysis (FEA) simulations, and curve-fit models for assessing remaining strength of X80 corroded pipelines for transporting hydrogen blended natural gas. Recently, Xie et al. [1] proposed a methodology to quantify the impact of HE on material properties and numerically determined burst pressure of X80 corroded pipelines. However, their HE quantification overestimated the degradation of tensile strength for hydrogen blending ratios beyond the original data range, and their FEA results of burst pressure are nonconservative. This work thus recharacterized the hydrogen concentration in the steel pipeline and the effect of HE on tensile strength, and then redetermined burst pressures for a set of typical corrosion defect cases considered by Xie et al. [1] based on an experimentally validated FEA modelling method. With the new FEA results, two empirical corrosion models were proposed for X80 corroded pipelines for hydrogen service. At zero hydrogen blending ratio, the novel empirical models predict burst pressures to be consistent with the industry-accepted corrosion models. Furthermore, both the numerical simulation method and the novel corrosion models are significant contributions to the pipeline industry and the hydrogen community. Application of these results will enhance the safety, reliability, and integrity of natural gas pipelines when used to transport hydrogen.
The daily conduct of high-risk, high-consequence work, by its very nature, can be mentally demanding. Research demonstrates that failure to manage or mitigate these demands can degrade psychological well-being and mental health. Degradations in employee well-being impact individual performance, jeopardizing safety and mission success in the workplace. This Commentary describes efforts taken at Sandia National Laboratories over the past eight years to evaluate, understand, learn from, and mitigate factors such as stress, burnout, work-life imbalances, and disengagement in the workplace that can degrade employee well-being. After evaluating these four facets of employee well-being, Sandia National Laboratories initiated several programs to address observations and outcomes, including the Thrive program, the Take 10 Initiative, work-life balance resources, employee resource groups such as the Sandia Parents Group, and Workplace Improvement Networks. Collectively, the intent of these programs is to ensure employee mental readiness to conduct hazardous high-risk work effectively and safely. Preliminary data suggest that these programs are succeeding. In conclusion, other national laboratories and organizations, regardless of size, may wish to apply similar approaches to improve employee well-being and thereby increase the likelihood of mission success.
Here, in this invited paper, we highlight some of our most recent work on the synthesis of low dimensional nanomaterials. Current graduate students and members of our group present four specific case systems: Nowotny-Juza phases, nickel phosphides, germanium-based core/shells, and organolead mixed-halide perovskites. Each system is accompanied by commentary from the student involved, which explains our motivation behind our work, as well as by a protocol detailing the key experimental considerations involved in their synthesis. We trust these and similar efforts by others and us will help further advance our understanding of the broader field of synthetic nanomaterials chemistry, while, at the same time, highlighting how important this area is to the development of new materials for technologically relevant applications.
Chemical safety education is a critical aspect of an integrated culture of safety in academic research settings. Showcasing best practices and sharing practical solutions for recognizing hazards and minimizing risks represent one way of reinforcing a research community's actions, attitudes, and behavior toward safety. For goals of improving chemical safety education with nonformal endeavors, safety moments are similar to 1-2 slides that focus on raising awareness and knowledge for routine safety issues in research laboratories. Intended to catalyze brief discussions at the beginning of meetings and presentations, these materials provide a proactive way for students and faculty to engage in open communication on diverse research safety topics across science and engineering. This commentary provides an overview of designing effective safety moments and tailoring them to highlight practical safety needs and considerations. Key components of model safety moment slides are presented, alongside centralized resources assembled by student-led laboratory safety teams, which can also be extended to posters, social media platforms, online videos, and other forms of scientific communication. Combined with both top-down backing from institution leaders and bottom-up support from student researchers, safety moments remain a low-barrier risk reduction strategy that is easy to implement, encourages local dialogue on safety, combats complacency, and holds potential for facilitating long-term improvements to academic lab safety culture.
Graduate training is a key element in producing a scientific workforce that reflects the nation’s diversity. This paper examines data from a 2013 American Chemical Society (ACS) survey of 2,544 chemistry masters and doctoral students and reveals barriers to reaching this goal. Multivariate statistical analyses indicate that women reported significantly less supportive relationships with advisors. Women were less likely to plan to finish their degrees, and for PhD students, the discrepancy was larger for students at the start of their graduate program. Women were also less likely to pursue the next level of training, and the gender difference related to postdoctoral plans was greater for those who identified with a racial-ethnic group traditionally underrepresented in chemistry (underrepresented minority, URM). URM students who were beyond the first year of their graduate program reported significantly less supportive relationships with peers. They were also less likely to have funding sufficient to meet their needs and more often used personal resources including loans. Despite these difficulties, URM students were more likely to definitely plan to finish their degrees, and men who identified as URM were more likely to plan to pursue postdoctoral work. Independent of gender and identification as URMs, students in more highly ranked schools reported less advisor support. Extensive open-ended comments indicated that large proportions of the students desired more attention and meaningful feedback from advisors and changes within their programs to promote support for students and advisor accountability. Suggestions for future research are given, and a companion commentary discusses needed directions for change.
STEM graduate education is vitally important in producing the talent needed to fuel our economy and provide solutions for the challenges we face in emerging diseases and climate change. Yet recent research indicates that women and students who identify as members of minority groups traditionally underrepresented in STEM face extraordinary challenges in their graduate careers. This commentary describes ways in which chemistry graduate education could become more supportive and inclusive through changes by graduate students, faculty, departments, funding agencies, and professional organizations. As a result the scientific workforce could utilize the full range of available talent and become more productive.
The geospace inner magnetosphere, within about ten Earth radii, contains various plasma populations with energy from a few eV to MeV and plays important roles in regulating the energy density of the magnetosphere, the magnetic field configuration, and wave dynamics. As an integrated part of the magnetosphere, the inner magnetosphere region also ties to other regions and can change the global geospace circulation. Therefore understanding both internal and external cross–energy/population interactions can help further our knowledge of the inner magnetosphere dynamics and non–linear feedback processes. In view of this, in the past five years (2014–2018), the GEM Focus Group (FG) “Inner magnetosphere cross–energy/population interactions (IMCEPI)” has gathered and boosted community–wide interactions among observation, simulation and modeling studies. As a result, this commentary reports some major accomplishments of the interactive inner magnetosphere community that were advanced by the IMCEPI FG discussions and layouts remaining challenges that need to be carried on.
There is growing interest in nexus research: energy‐water, energy‐water‐land, and more recently food‐energy‐water. Motivating this movement is the recognition that the dynamics and feedbacks that constitute these nexuses have been overlooked in the past but are critical to the planning and management of these interacting elements. Formal reviews have identified gaps in current studies. In this commentary, we highlight additional oversights that are hindering integration of findings in nexus studies, notably usage of imprecise terminology to describe analyses, a failure to close the loop by linking production with corresponding waste streams, and exclusion of dynamics linking diverse constituent elements. Equally lacking from current nexus studies is a consistent protocol for communicating the conceptual basis of our studies. To fill this gap, we draw on diverse perspectives and fields to propose a comprehensive and systematic framework that can guide the model conceptualization phase of nexus studies. We also present a standardized documentation practice (similar to one utilized by the agent‐based modeling community) to facilitate communication of nexus studies. These initiatives can improve our ability to account for and communicate the nuanced, food‐energy‐water nexus interactions in a consistent manner, which is necessary to better inform risk analysis and avoid decisions with unintended consequences and hidden costs to society.