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At least 91 records · Page 5

What Aspects of Personal Care Are Most Important to Patients Undergoing Radiation Therapy for Prostate Cancer?

Purpose/Objective: The overall quality of patient care is a function of the quality of both its technical and its nontechnical components. The purpose of this study was to identify the elements of nontechnical (personal) care that are most important to patients undergoing radiation therapy for prostate cancer. Methods and Materials: We reviewed the literature and interviewed patients and health professionals to identify elements of personal care pertinent to patients undergoing radiation therapy for prostate cancer. We identified 143 individual elements relating to 10 aspects of personal care. Patients undergoing radical radiation therapy for prostate cancer completed a self-administered questionnaire in which they rated the importance of each element. The overall importance of each element was measured by the percentage of respondents who rated it as “very important.” The importance of each aspect of personal care was measured by the mean importance of its elements. Results: One hundred eight patients completed the questionnaire. The percentage of patients who rated each element “very important” ranged from 7% to 95% (mean 61%). The mean importance rating of the elements of each aspect of care varied significantly: “perceived competence of caregivers,” 80%; “empathy and respectfulness of caregivers,” 67%; “adequacy of information sharing,” 67%; “patient centeredness,” 59%; “accessibility of caregivers,” 57%; “continuity of care,” 51%; “privacy,” 51%; “convenience,” 45%; “comprehensiveness of services,” 44%; and “treatment environment,” 30% (P<.0001). Neither age nor education was associated with importance ratings, but the patient's health status was associated with the rating of some elements of care. Conclusions: Many different elements of personal care are important to patients undergoing radiation therapy for prostate cancer, but the 3 aspects of care that most believe are most important are these: the perceived competence of their caregivers, the empathy and respectfulness of their caregivers, and the adequacy of information sharing.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Tunable Atomic Layer Deposition into Ultra-High-Aspect-Ratio (>60000:1) Aerogel Monoliths Enabled by Transport Modeling

Atomic layer deposition (ALD) modification of ultra-high-aspect-ratio structures (>10,000:1) is a powerful platform with applications in catalysis, filtration, and energy conversion. However, the deposition of conformal and tunable ALD coatings at these aspect ratios remains challenging, resulting in empirical tradeoffs between precursor utilization and reaction time. Here, we demonstrate tunable control of the ALD infiltration depth into an aerogel monolith (AM) and develop a reaction-diffusion model to accurately describe the coating process. Specifically, we investigate the ALD exposure time and precursor dose needed to conformally coat a silica AM with pore sizes of ~20 nm, a monolith thickness of ~2.5 mm, and aspect ratios exceeding 60,000:1. We demonstrate complete infiltration into the AM, which is quantified by elemental mapping. A reaction-diffusion model is developed, which accounts for multiple doses and precursor depletion in the ALD chamber during an exposure step. The experimentally validated model enables the prediction and tuning of infiltration depth into a tortuous, high-aspect-ratio structure such as an AM, allowing for the synthesis of rationally designed material architectures. Additionally, the model allows for co-optimization of the total deposition time and percentage of unreacted precursor, which are important for the manufacturability and sustainability of ALD processing. Lastly, we demonstrate that ultra-thin ALD Al 2 O 3 coatings can be used to stabilize silica AMs against structural degradation under high-temperature annealing conditions (700-800 °C), by limiting changes in surface area and monolith volume. As a result, this improved high-temperature stability has implications for numerous aerogel applications, including catalysis and thermal insulation.

14 SOLAR ENERGY↗

On virial analysis at low aspect ratio

The validity of virial analysis to infer global MHD equilibrium poloidal beta β p and internal inductance ℓ i from external magnetics measurements is examined for low aspect ratio configurations with A < 2. Numerical equilibrium studies at varied aspect ratio are utilized to validate the technique at finite aspect ratio. The effect of applying high-A approximations to low-A experimental data is quantified and demonstrates significant over-estimation of stored energy (factors of 2–10) in spherical tokamak geometry. Experimental approximations to equilibrium-dependent volume integral terms in the analysis are evaluated at low-A. Highly paramagnetic configurations are found to be inadequately represented through the virial mean radius parameter R T . Alternate formulations for inferring β p and ℓ i that are independent of R T to avoid this difficulty are presented for the static isotropic limit. Lastly, these formulations are suitable for fast estimation of tokamak stored energy components at low aspect ratio using virial analysis.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

High- β equilibrium and ballooning stability of the low aspect ratio CNT stellarator

In the paper, the existence and ballooning-stability of low aspect ratio stellarator equilibria is predicted for the Columbia Neutral Torus (CNT) with the aid of 3D numerical tools. In addition to having a low aspect ratio, CNT is characterized by a low magnetic field and small plasma volume. Also, highly overdense plasmas were recently heated in CNT by means of microwaves. These characteristics suggest that CNT might attain relatively high values of plasma beta and thus be of use in the experimental study of stellarator stability to high-beta instabilities such as ballooning modes. As a first step in that direction, here the ballooning stability limit is found numerically. Depending on the particular magnetic configuration we expect volume-averaged β limits in the range 0.9%–3.0%, and possibly higher, and observe indications of a second region of ballooning stability. As the aspect ratio is reduced, stability is found to increase in some configurations and decrease in others. Energy-balance estimates using stellarator scaling laws indicate that the lower β limit may be attainable with overdense heating at powers of 40 to 100 kW. The present study serves the additional purpose of testing VMEC and other stellarator codes at high values of β and at low aspect ratios. For this reason, the study was carried out both for free boundary, for maximum fidelity to experiment, as well as with a fixed boundary, as a numerical test.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Global gyrokinetic study of shaping effects on electromagnetic modes at NSTX aspect ratio with ad hoc parallel magnetic perturbation effects

Plasma shaping may have a stronger effect on global turbulence in tight-aspect-ratio tokamaks than in conventional-aspect-ratio tokamaks due to the higher toroidicity and more acute poloidal asymmetry in the magnetic field. In addition, previous local gyrokinetic studies have shown that it is necessary to include parallel magnetic field perturbations in order to accurately compute growth rates of electromagnetic modes in tight-aspect-ratio tokamaks. In this work, the effects of elongation and triangularity on global, ion-scale, linear electromagnetic modes are studied at National Spherical Torus Experiment (NSTX) aspect ratio and high plasma β using the global gyrokinetic particle-in-cell code XGC. The effects of compressional magnetic perturbations are approximated via a well-known modification to the particle drifts that was developed for flux-tube simulations [Joiner et al., Phys. Plasmas 17, 072104 (2010)], without proof of its validity in a global simulation, with the gyrokinetic codes GENE and GEM being used for local verification and global cross-verification. Magnetic equilibria are re-constructed for each distinct plasma profile that is used. Coulomb collision effects are not considered. Within the limitations imposed by the present study, it is found that linear growth rates of electromagnetic modes (collisionless microtearing modes and kinetic ballooning modes) are significantly reduced in a high-elongation and high-triangularity NSTX-like geometry compared to a circular NSTX-like geometry. For example, growth rates of kinetic ballooning modes at high- β are reduced to the level of that of collisionless trapped electron modes.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Plasma Focused Ion Beam Milling of High-Aspect-Ratio Holes in Diamond

Plasma focused ion beam (PFIB) technology has a great potential for applications requiring rapid micro-machining of high-aspect-ratio features. Here, we use 30-keV Ar, Xe, and O 2 ion beams to study PFIB milling of high-aspect-ratio circular holes in polycrystalline diamond. Our results show that Xe and O 2 ion beams have the highest milling efficiency for low-aspect-ratio and high-aspect-ratio hole milling, respectively. Each ion beam species produces holes with its characteristic shape and wall surface morphology. In conclusion, based on these results, we demonstrate a “hybrid” hole milled in a two-step process with Xe and O 2 ion beams with the geometry and wall morphology attractive for the attachment of a fuel fill tube to the inertial confinement fusion capsule.

ICF targets↗

Fabrication of model ultrafiltration membranes with uniform, high aspect ratio pores

Here, in this manuscript, we report the facile fabrication of large-area model membranes with highly uniform and high aspect ratio pores with diameters <20 nm. These membranes are useful for fundamental investigations of separation by size exclusion in the ultrafiltration regime, where species to be separated from solution have dimensions of 1–100 nm. Such investigations require membranes with narrow pores and high aspect ratios such that the Hagen–Poiseuille equation is followed, enabling well-known models such as the hindered transport model to be evaluated and other affecting factors to be ignored. We demonstrate that the sub-20 nm pores in the membrane are of sufficiently high aspect ratio such that water flux through the membrane is consistent with the Hagen–Poiseuille equation. The fabrication relies on self-assembling block copolymers to form uniform, densely packed patterns with sub-20 nm resolution, sequential infiltration synthesis to convert the block copolymer in situ into a mask with adequate contrast to etch pores with an aspect ratio >5, and low-resolution photolithography to transfer the pattern over a large area into a silicon nitride membrane. Model membranes with narrow pore-size distribution fabricated in this way provide the means to investigate parameters that impact size-selective ultrafiltration separations such as the relationships between solute or particle size and pore size, their distributions, and rejection profiles, and, therefore, test the validity or limits of separation models.

Chen, Wen↗

Attention-based Aspect Reasoning for Knowledge Base Question Answering on Clinical Notes

Question Answering (QA) in clinical notes has gained a lot of attention in the past few years. Existing machine reading comprehension approaches in clinical domain can only handle questions about a single block of clinical texts and fail to retrieve information about different patients and clinical notes. To handle more complex questions, we aim at creating knowledge base from clinical notes to link different patients and clinical notes, and performing knowledge base question answering (KBQA). Based on the expert annotations in n2c2, we first created the ClinicalKBQA dataset that includes 8,952 QA pairs and covers questions about seven medical topics through 322 question templates. Then, we proposed an attention-based aspect reasoning (AAR) method for KBQA and investigated the impact of different aspects of answers (e.g., entity, type, path, and context) for prediction. The AAR method achieves better performance due to the well-designed encoder and attention mechanism. In the experiments, we find that both aspects, type and path, enable the model to identify answers satisfying the general conditions and produce lower precision and higher recall. On the other hand, the aspects, entity and context, limit the answers by node-specific information and lead to higher precision and lower recall.

Wang, Ping↗

Design Guide for Pitch-Up Evaluation and Investigation at High Subsonic Speeds of Possible Limitations Due to Wing-Aspect-Ratio Variations

A design guide is suggested as a basis for indicating combinations of airplane design variables for which the possibilities of pitch-up are minimized for tail-behind-wing and tailless airplane configurations. The guide specifies wing plan forms that would be expected to show increased tail-off stability with increasing lift and plan forms that show decreased tail-off stability with increasing lift. Boundaries indicating tail-behind-wing positions that should be considered along with given tail-off characteristics also are suggested. An investigation of one possible limitation of the guide with respect to the effects of wing-aspect-ratio variations on the contribution to stability of a high tail has been made in the Langley high-speed 7- by 10-foot tunnel through a Mach number range from 0.60 to 0.92. The measured pitching-moment characteristics were found to be consistent with those of the design guide through the lift range for aspect ratios from 3.0 to 2.0. However, a configuration with an aspect ratio of 1.55 failed t o provide the predicted pitch-up warning characterized by sharply increasing stability at the high lifts following the initial stall before pitching up. Thus, it appears that the design guide presented herein might not be applicable when the wing aspect ratios lower than about 2.0.

Spreemann, Kenneth P.↗

Required critical aspect ratio of fibers intended for stress rupture applications.

The observed critical aspect ratio for pullout specimens of tungsten wire in a copper matrix tested in stress rupture at 649 and 816 C was slightly greater than for tension tests at the same temperature. Time for failure of the stress rupture specimens was controlled by the properties of the fiber (tungsten) at aspect ratios greater than the critical aspect ratio and by the properties of the matrix (copper) at aspect ratios less than the critical ratio.

Jech, R. W.↗

A study of high-altitude manned research aircraft employing strut-braced wings of high-aspect-ratio

The effect of increased wing aspect ratio of subsonic aircraft on configurations with and without strut bracing. Results indicate that an optimum cantilever configuration, with a wing aspect ratio of approximately 26, has a 19% improvement in cruise range when compared to a baseline concept with a wing aspect ratio of approximately 10. An optimum strut braced configuration, with a wing aspect ratio of approximately 28, has a 31% improvment in cruise range when compared to the same baseline concept. This improvement is mainly due to the estimated reduction in wing weight resulting from use of lifting struts. All configurations assume the same mission payload and fuel. The drag characteristics of the wings are enhanced with the use of laminar flow airfoils. A method for determining the extent of attainable natural laminar flow, and methods for preliminary structural design and for aerodynamic analysis of wings lifting struts are presented.

Smith, P. M.↗

Theoretical-Numerical Study of Feasibility of Use of Winglets on Low Aspect Ration Wings at Subsonic and Transonic Mach Numbers to Reduce Drag

A numerical design study was conducted to assess the drag reduction potential of winglets installed on a series of low aspect ratio wings at a design point of M=0.8, C sub L=0.3. Wing-winglet and wing-alone design geometries were obtained for wings of aspect ratios between 1.75 and 2.67, having leading edge sweep angles between 45 and 60 deg. Winglet length was fixed at 15% of wing semispan. To assess the relative performance between wing-winglet and wing-alone configurations, the PPW nonlinear extended small disturbance potential flow code was utilized. This model has proven to yield plausible transonic flow field simulations for the series of low aspect ratio configurations selected. Predicted decreases in pressure drag coefficient for the wing-winglet configurations relative to the corresponding wing-alone planform are about 15% at the design point. Predicted decreases in wing-winglet total drag coefficient are about 12%, relative to the corresponding wing-alone design. Longer winglets (25% of the wing semispan) yielded decreases in the pressure drag of up to 22% and total drag of up to 16.4%. These predicted drag coefficient reductions are comparable to reductions already demonstrated by actual winglet designs installed on higher aspect ratio transport type aircraft.

Kuhlman, John M.↗

Augmented heat transfer in rectangular channels of narrow aspect ratios with rib turbulators

The effects of the rib angle-of-attack on the distributions of the local heat transfer coefficient and on the friction factors in short rectangular channels of narrow aspect ratios with a pair of opposite rib-roughened walls are determined for Reynolds numbers from 10,000 to 60,000. The channel width-to-height ratios are 2/4 and 1/4; the corresponding rib angles-of-attack are 90, 60, 45, and 30 deg, respectively. The results indicate that the narrow-aspect-ratio channels give better heat transfer performance than the wide-aspect-ratio channels for a constant pumping power. Semiempirical friction and heat transfer correlations are obtained. The results can be used in the design of turbine cooling channels of narrow aspect ratios.

Han, J. C.↗

Alternative descriptions of wave and particle aspects of the harmonic oscillator

The dynamical properties of the wave and particle aspects of the harmonic oscillator can be studied with the help of the time-dependent Schroedinger equation (SE). Especially the time-dependence of maximum and width of Gaussian wave packet solutions allow to show the evolution and connections of those two complementary aspects. The investigation of the relations between the equations describing wave and particle aspects leads to an alternative description of the considered systems. This can be achieved by means of a Newtonian equation for a complex variable in connection with a conservation law for a nonclassical angular momentum-type quantity. With the help of this complex variable, it is also possible to develop a Hamiltonian formalism for the wave aspect contained in the SE, which allows to describe the dynamics of the position and momentum uncertainties. In this case the Hamiltonian function is equivalent to the difference between the mean value of the Hamiltonian operator and the classical Hamiltonian function.

Schuch, Dieter↗

The Hydrodynamic Characteristics of Modified Rectangular Flat Plates Having Aspect Ratios of 1.00, 0.25, and 0.125 and Operating near a Free Water Surface

Report presents the results of an investigation conducted to determine the hydrodynamic forces and moments acting on modified rectangular flat plates with aspect ratios of 1.00, 0.25, and 0.125 mounted on a single strut and operating at several depths of submersion. A simple method has been developed by modification of Falkner's vortex-lattice theory which enables the prediction of the lift characteristics in unseparated flow at large depths. This method shows good agreement with experimental data from the present tests and with aerodynamic data at all angles investigated for aspect ratios of 1.00 and 0.25 and at angles up to 16 degrees for aspect ratio 0.125. Above 16 degrees for aspect ratio 0.125, the predicted lift proved too high.

Wadlin, Kenneth L↗

Experimental investigation of the effect of aspect ratio and Mach number on the flutter of cantilever wings

The results of some wind-tunnel experiments to investigate the effects of aspect ratio and Mach number on the flutter of uniform, unswept, cantilever wings are reported. Models having aspect ratios ranging from 2 to 13 were tested at Mach numbers up to 0.92. No general attempt is made to correlate the data with three-dimensional-flow theory, but an examination of the data is made on the basis of reference theoretical values obtained from the two-dimensional incompressible-flow theory. On this basis a reduction in aspect ratio, in general, increased the ratio of the experimental flutter speed to the calculated flutter speed. The analysis also indicated that for a given aspect ratio, this ratio decreased slightly as the Mach number is increased.

Widmayer, E , Jr↗

CFD Assessment of Orifice Aspect Ratio and Mass Flow Ratio on Jet Mixing in Rectangular Ducts

Isothermal CFD analysis was performed on axially opposed rows of jets mixing with cross flow in a rectangular duct. Laterally, the jets' centerlines were aligned with each other on the top and bottom walls. The focus of this study was to characterize the effects of orifice aspect ratio and jet-to-mainstream mass flow ratio on jet penetration and mixing. Orifice aspect ratios (L/W) of 4-to-1, 2-to-1, and 1-to-1, along with circular holes, were parametrically analyzed. Likewise, jet-to-mainstream mass flow ratios (MR) of 2.0, 0.5, and 0.25 were systematically investigated. The jet-to-mainstream momentum-flux ratio (J) was maintained at 36 for all cases, and the orifice spacing-to-duct height (S/H) was varied until optimum mixing was attained for each configuration. The numerical results showed that orifice aspect ratio (and likewise orifice blockage) had little effect on jet penetration and mixing. Based on mixing characteristics alone, the 4-to-1 slot was comparable to the circular orifice. The 4-to-1 slot has a smaller jet wake which may be advantageous for reducing emissions. However, the axial length of a 4-to-1 slot may be prohibitively long for practical application, especially for MR of 2.0. The jet-to-mainstream mass flow ratio had a more significant effect on jet penetration and mixing. For a 4-to-1 aspect ratio orifice, the design correlating parameter for optimum mixing (C = (S/H)(sq. root J)) varied from 2.25 for a mass flow ratio of 2.0 to 1.5 for a mass flow ratio of 0.25.

Bain, D. B.↗

Visualization of Secondary Flow Development in High Aspect Ratio Channels with Curvature

The results of an experimental project to visually examine the secondary flow structure that develops in curved, high aspect-ratio rectangular channels are presented. The results provide insight into the fluid dynamics within high aspect ratio channels. A water flow test rig constructed out of plexiglass, with an adjustable aspect ratio, was used for these experiments. Results were obtained for a channel geometry with a hydraulic diameter of 10.6 mm (0.417 in.), an aspect ratio of 5.0, and a hydraulic radius to curvature radius ratio of 0.0417. Flow conditions were varied to achieve Reynolds numbers up to 5,100. A new particle imaging velocimetry technique was developed which could resolve velocity information from particles entering and leaving the field of view. Time averaged secondary flow velocity vectors, obtained using this velocimetry technique, are presented for 30 degrees, 60 degrees, and 90 degrees into a 180 degrees bend and at a Reynolds number of 5,100. The secondary flow results suggest the coexistence of both the classical curvature induced vortex pair flow structure and the eddies seen in straight turbulent channel flow.

Meyer, Michael L.↗