Physiologic effects of exposure to increased oxygen tension at 5 psia
Physiological effects on humans exposed to increased oxygen tension in space cabin at simulated altitude of 27,000 feet for 14 days
ALTITUDE SIMULATION↗
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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.
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Removing Pathogens Using Nano-Ceramic-Fiber Filters
A nano-aluminum-oxide fiber of only 2 nanometers in diameter was used to develop a ceramic-fiber filter. The fibers are electropositive and, when formulated into a filter material (NanoCeram(TradeMark)), would attract electro-negative particles such as bacteria and viruses. The ability to detect and then remove viruses as well as bacteria is of concern in space cabins since they may be carried onboard by space crews. Moreover, an improved filter was desired that would polish the effluent from condensed moisture and wastewater, producing potable drinking water. A laboratory- size filter was developed that was capable of removing greater than 99.9999 percent of bacteria and virus. Such a removal was achieved at flow rates hundreds of times greater than those through ultraporous membranes that remove particles by sieving. Because the pore size of the new filter was rather large as compared to ultraporous membranes, it was found to be more resistant to clogging. Additionally, a full-size cartridge is being developed that is capable of serving a full space crew. During this ongoing effort, research demonstrated that the filter media was a very efficient adsorbent for DNA (deoxyribonucleic acid), RNA (ribonucleic acid), and endotoxins. Since the adsorption is based on the charge of the macromolecules, there is also a potential for separating proteins and other particulates on the basis of their charge differences. The separation of specific proteins is a major new thrust of biotechnology. The principal application of NanoCeram filters is based on their ability to remove viruses from water. The removal of more than 99.9999 percent of viruses was achieved by a NanoCeram polishing filter added to the effluent of an existing filtration device. NanoCeram is commercially available in laboratory-size filter discs and in the form of a syringe filter. The unique characteristic of the filter can be demonstrated by its ability to remove particulate dyes such as Metanyl yellow. Its particle size is only 2 nanometers, about the size of a DNA molecule, yet the NanoCeram syringe filter is capable of retaining the dyes as the fluid is passed through the syringe, without much back-pressure. Endotoxins, which are contaminants that are part of the residue of destroyed bacteria, can cause toxic shock and are therefore of major concern in pharmaceutical products. The NanoCeram syringe filter is capable of removing greater than 99.96 percent of the endotoxins.
Tepper, Frederick↗
The role of toxicology in the Apollo space program
Some of the major considerations are presented which governed the formation and application of the toxicology program employed in support of the Apollo program. The overriding concern of the program was the safety of crews exposed to trace contaminant gases for extended periods of time. The materials screening program employed, in conjunction with a well designed spacecraft environmental control system, helped to attain the goals set forth for the Apollo program. The knowledge gained from working with the toxicity problems and the identification of compounds in the space cabin atmosphere are of importance for continued efforts in manned space flight. Tabular data of spacecraft contaminants are presented.
Wayland J. Rippstein, Jr↗
Legacy of Environmental Research During the Space Shuttle Program
The Space Shuttle Program provided many opportunities to study the role of spaceflight on human life for over the last 30 years and represents the longest and largest U.S. human spaceflight program. Risks to crewmembers were included in the research areas of nutrition, microbiology, toxicology, radiation, and sleep quality. To better understand the Shuttle environment, Crew Health Care System was developed. As part of this system, the Environmental Health Subsystem was developed to monitor the atmosphere for gaseous contaminants and microbial contamination levels and to monitor water quality and radiation. This program expended a great deal of effort in studying and mitigating risks related to contaminations due to food, water, air, surfaces, crewmembers, and payloads including those with animals. As the Shuttle had limited stowage space and food selection, the development of nutritional requirements for crewmembers was imperative. As the Shuttle was a reusable vehicle, microbial contamination was of great concern. The development of monitoring instruments that could withstand the space environment took several years and many variations to come up with a suitable instrument. Research with space radiation provided an improved understanding of the various sources of ionizing radiation and the development of monitoring instrumentation for space weather and the human exposure within the orbiter's cabin. Space toxicology matured to include the management of offgassing products that could pollute the crewmembers air quality. The Shuttle Program implemented a 5-level toxicity rating system and developed new monitoring instrumentation to detect toxic compounds. The environment of space caused circadian desynchrony, sleep deficiency, and fatigue leading to much research and major emphasis on countermeasures. Outcomes of the research in these areas were countermeasures, operational protocols, and hardware. Learning Objectives: This symposium will provide an overview of the major environmental lessons learned and the development of countermeasures, monitoring hardware, and procedures.
Lane, Helen W.↗
Effect of emerging technology on a convertible, business/interceptor, supersonic-cruise jet
This study was initiated to assess the feasibility of an eight-passenger, supersonic-cruise long range business jet aircraft that could be converted into a military missile carrying interceptor. The baseline passenger version has a flight crew of two with cabin space for four rows of two passenger seats plus baggage and lavatory room in the aft cabin. The ramp weight is 61,600 pounds with an internal fuel capacity of 30,904 pounds. Utilizing an improved version of a current technology low-bypass ratio turbofan engine, range is 3,622 nautical miles at Mach 2.0 cruise and standard day operating conditions. Balanced field takeoff distance is 6,600 feet and landing distance is 5,170 feet at 44,737 pounds. The passenger section from aft of the flight crew station to the aft pressure bulkhead in the cabin was modified for the interceptor version. Bomb bay type doors were added and volume is sufficient for four advanced air-to-air missiles mounted on a rotary launcher. Missile volume was based on a Phoenix type missile with a weight of 910 pounds per missile for a total payload weight of 3,640 pounds. Structural and equipment weights were adjusted and result in a ramp weight of 63,246 pounds with a fuel load of 30,938 pounds. Based on a typical intercept mission flight profile, the resulting radius is 1,609 nautical miles at a cruise Mach number of 2.0.
Beissner, F. L., Jr.↗
Integrated Testing of a Carbon Dioxide Removal Assembly and a Temperature-Swing Adsorption Compressor for Closed-Loop Air Revitalization
Accumulation and subsequent compression of carbon dioxide that is removed from space cabin are two important processes involved in a closed-loop air revitalization scheme of the International Space Station (ISS). The carbon dioxide removal assembly (CDRA) of ISS currently operates in an open loop mode without a compressor. This paper describes the integrated test results of a flight-like CDRA and a temperature-swing adsorption compressor (TSAC) for carbon dioxide removal and compression. The paper provides details of the TSAC operation at various CO2 loadings and corresponding performance of CDRA.
Knox, J. C.↗
Integrated Testing of a 4-Bed Molecular Sieve and a Temperature-Swing Adsorption Compressor for Closed-Loop Air Revitalization
Accumulation and subsequent compression of carbon dioxide that is removed from space cabin are two important processes involved in a closed-loop air revitalization scheme of the International Space Station (ISS). The 4-Bed Molecular Sieve (4BMS) of ISS currently operates in an open loop mode without a compressor. This paper reports the integrated 4BMS and liquid-cooled TSAC testing conducted during the period of March 3 to April 18, 2003. The TSAC prototype was developed at NASA Ames Research Center (ARC). The 4BMS was modified to a functionally flight-like condition at NASA Marshall Space Flight Center (MSFC). Testing was conducted at MSFC. The paper provides details of the TSAC operation at various CO2 loadings and corresponding performance of CDRA.
Knox, James C.↗
Integrated Testing of a 4-Bed Molecular Sieve, Air-Cooled Temperature Swing Adsorption Compressor, and Sabatier Engineering Development Unit
Accumulation and subsequent compression of carbon dioxide that is removed from the space cabin are two important processes involved in a closed-loop air revitalization scheme of the International Space Station (ISS). The 4-Bed Molecular Sieve (4BMS) of ISS currently operates in an open loop mode without a compressor. The Sabatier Engineering Development Unit (EDU) processes waste CO2 to provide water to the crew. This paper reports the integrated 4BMS, air-cooled Temperature Swing Adsorption Compressor (TSAC), and Sabatier EDU testing. The TSAC prototype was developed at NASA Ames Research Center (ARC). The 4BMS was modified to a functionally flight-like condition at NASA Marshall Space Flight Center (MSFC). Testing was conducted at MSFC. The paper provides details of the TSAC operation at various CO2 loadings and corresponding performance of the 4BMS and Sabatier.
Knox, James C.↗
Electronic nose for space program applications
The ability to monitor air contaminants in the shuttle and the International Space Station is important to ensure the health and safety of astronauts, and equipment integrity. Three specific space applications have been identified that would benefit from a chemical monitor: (a) organic contaminants in space cabin air; (b) hypergolic propellant contaminants in the shuttle airlock; (c) pre-combustion signature vapors from electrical fires. NASA at Kennedy Space Center (KSC) is assessing several commercial and developing electronic noses (E-noses) for these applications. A short series of tests identified those E-noses that exhibited sufficient sensitivity to the vapors of interest. Only two E-noses exhibited sufficient sensitivity for hypergolic fuels at the required levels, while several commercial E-noses showed sufficient sensitivity of common organic vapors. These E-noses were subjected to further tests to assess their ability to identify vapors. Development and testing of E-nose models using vendor supplied software packages correctly identified vapors with an accuracy of 70-90%. In-house software improvements increased the identification rates between 90 and 100%. Further software enhancements are under development. Details on the experimental setup, test protocols, and results on E-nose performance are presented in this paper along with special emphasis on specific software enhancements. c2003 Elsevier Science B.V. All rights reserved.
Air Pollution, Indoor/analysis↗
Solid State Air Purification System
Life support systems in spacecraft are designed to provide a safe, habitable environment for the astronauts, and one of the most significant challenges is managing acceptable air quality. Carbon dioxide (CO2) is respired normally by humans at concentrations that are toxic if inhaled directly, and as a result cabin air must be tightly managed. The Carbon Dioxide Removal Assembly (CDRA) currently on board the ISS is the best functioning technology for manned space cabins, but has two significant drawbacks:1. The CDRA requires that air be dried prior to CO2 capture, and this costs energy _ in fact, the system spends 4X more energy drying the air than in actually capturing and releasing carbon dioxide. 2. The CDRA works in batch mode, while downstream CO2 processing systems require a continuous stream of CO2. This adds unnecessary complexity, as well as a second parasitic energy loss.An ideal system would process CO2 continuously without any need for drying of the air, and without any moving parts. Such a system would require a fraction of the size and weight of the CDRA while dropping the cost of CO2 capture by 5X or more. Such a technology would be enabling for future long term manned flight missions, such as a mission to Mars. eSionic is developing a new electrochemical membrane technology using its patented innovations in electrolyte materials. In Phase I of this program eSionic has demonstrated continuous gas separation using only electricity to drive the separation, with no moving parts or pressure drops. In Phase II, eSionic will demonstrate long-term operation of the membranes consistent with the needs of NASA for this development program.
Life Support↗
Effect of 90-day continuous exposure to methylisobutylketone on dogs, monkeys and rats
Continuous exposure of rats, dogs and monkeys to 410 mg/cu M methylisobutylketone vapor (MIBK) was conducted to evaluate the provisional spacecraft exposure limit of 20 ppm established by the Space Science Board in 1968. The exposure, conducted in a simulated space cabin environment, did not produce any measurable changes in dogs or monkeys. Rats developed hyaline droplet nephrosis within 2 weeks of exposure which was reversible upon removal from the MIBK even after 90 days. The data obtained indicated that the 60-minute emergency exposure limit of 100 ppm and the 90- and 1000-day provisional limits as established by the Space Science Board contain a wide margin of safety.
Macewen, J. D.↗
Changes in the immune system during and after spaceflight
The results of immunological analyses before, during and after spaceflight, have established the fact that spaceflight can result in a blunting of the immune mechanisms of human crew members and animal test species. There is some evidence that the immune function changes in short-term flights resemble those occurring after acute stress, while the changes during long-term flights resemble those caused by chronic stress. In addition, this blunting of the immune function occurs concomitant with a relative increase in potentially infectious microorganisms in the space cabin environment. This combination of events results in an increased probability of inflight infectious events. The realization of this probability has been shown to be partially negated by the judicious use of a preflight health stabilization program and other operational countermeasures. The continuation of these countermeasures, as well as microbial and immunological monitoring, are recommended for continued spaceflight safety.
manned↗
Sanitary devices in pressurized capsules
Sanitary devices for animals in sealed space cabin
ANIMAL STUDY↗
Effects of Atmospheric Environment on Flammability of Fabrics and Carbonaceous Solids
In this chapter and in the others to follow, an attempt will be made to outline empirical studies which shed some light on the effects of internal atmospheric conditions on the fire hazard in space cabins. The results of these experiments will be interpreted, whenever possible, in light of the theoretical considerations outlined in Chapter 1.
Roth, Emanuel M.↗
Effects of Atmospheric Environment on Flammability of Gases, Liquids, and Vapors
Effects of space cabin atmosphere on flammability of liquids and gases
Roth, Emanuel M.↗
Fire and Blast Hazards from Meteoroid Penetration
Fire and flash hazards from meteoroid penetration of space cabin
Roth, Emanuel M.↗
The use of silver oxide as a regenerative carbon dioxide sorbent
Regenerative silver oxide sorbent development for carbon dioxide removal from space cabin atmospheres
CABIN ATMOSPHERE↗
Gaseous contaminant removal by adsorption.
Correlation and prediction of adsorption levels of gaseous contaminants for removal from space cabin atmospheres
CHEMISORPTION↗