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DOE OSTI2019

Microwave Multiplexing on the Keck Array

In this paper, we describe an on-sky demonstration of a microwave-multiplexing readout system in one of the receivers of the Keck Array, a polarimetry experiment observing the cosmic microwave background at the South Pole. During the austral summer of 2018–2019, we replaced the time-division multiplexing readout system with microwave-multiplexing components including superconducting microwave resonators coupled to radio frequency superconducting quantum interference devices at the sub-Kelvin focal plane, coaxial-cable plumbing and amplification between room temperature and the cold stages, and a SLAC Microresonator Radio Frequency system for the warm electronics. In the range 5–6 GHz, a single coaxial cable reads out 528 channels. The readout system is coupled to transition-edge sensors, which are in turn coupled to 150-GHz slot-dipole phased-array antennas. Observations began in April 2019, and we report here on an initial characterization of the system performance.

79 ASTRONOMY AND ASTROPHYSICS↗

DOE OSTI2020

Performance of a low-parasitic frequency-domain multiplexing readout

Frequency-domain multiplexing is a readout technique for transition-edge sensor bolometer arrays used on modern cosmic microwave background experiments, including the SPT-3G receiver. Here, we present design details and performance measurements for a low-parasitic frequency-domain multiplexing readout. Reducing the parasitic impedance of the connections between cryogenic components provides a path to improve both the crosstalk and noise performance of the readout. Reduced crosstalk will in turn allow higher-multiplexing factors. We have demonstrated a factor of two improvement in parasitic resistance compared to SPT-3G hardware. Reduced parasitics also permits operation of lower-resistance bolometers optimized for improved readout noise performance. We demonstrate that a module in the prototype system has comparable readout noise performance to an SPT-3G module when operated with dark TES bolometers in the laboratory.

frequency-domain multiplexing↗

DOE OSTI2020

Simons Observatory Microwave SQUID Multiplexing Readout: Cryogenic RF Amplifier and Coaxial Chain Design

The Simons Observatory (SO) is an upcoming polarization-sensitive cosmic microwave background experiment on the Cerro Toco Plateau (Chile) with large overlap with other optical and infrared surveys (e.g., DESI, LSST, HSC). To enable the readout of O(10,000) detectors in each of the four telescopes of SO, we will employ the microwave SQUID multiplexing technology. With a targeted multiplexing factor of O(1000), microwave SQUID multiplexing has never been deployed on the scale needed for SO. Here we present the design of the cryogenic coaxial cable and RF component chain that connects room temperature readout electronics to superconducting resonators that are coupled to transition edge sensor bolometers operating at sub-Kelvin temperatures. We describe design considerations including cryogenic RF component selection, system linearity, noise, and thermal power dissipation.

47 OTHER INSTRUMENTATION↗

DOE OSTI2022

Bandwidth and Aliasing in the Microwave SQUID Multiplexer

The microwave SQUID multiplexer (μmux) has enabled higher bandwidth or higher channel counts across a wide range of experiments in particle physics, astronomy, and spectroscopy. The large multiplexing factor coupled with recent commercial availability of microwave components and warm electronics readout systems make it an attractive candidate for systems requiring large cryogenic detector counts. Since the multiplexer is considered for both bolometric and calorimetric applications across several orders of magnitude of signal frequencies, understanding the bandwidth of the device and its interaction with readout electronics is key to appropriately designing and engineering systems. Here we discuss several important factors contributing to the bandwidth properties of μmux systems, including the intrinsic device bandwidth, interactions with warm electronics readout systems, and aliasing. Further, we present simulations and measurements of μmux devices coupled with SLAC Microresonator RF (SMuRF) tone-tracking electronics and discuss several implications for future experimental design.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

DOE OSTI2024

Understanding the Phase of Responsivity and Noise Sources in Frequency-Domain Multiplexed Readout of Transition Edge Sensor Bolometers

Abstract Cosmic microwave background (CMB) experiments have deployed focal planes with $$\mathcal {O}(10^{4})$$ O ( 10 4 ) transition edge sensor (TES) bolometers cooled to sub-Kelvin temperatures by multiplexing the readout of many TES channels onto a single pair of wires. Digital Frequency-domain Multiplexing (DfMux) is a multiplexing technique used in many CMB polarization experiments, such as the Simons Array, SPT-3 G, and EBEX. The DfMux system studied here uses LC filters with resonant frequencies ranging from 1.5 to 4.5 MHz connected to an array of TESs. Each detector has an amplitude-modulated carrier tone at the resonant frequency of its accompanying LC resonator. The signal is recovered via quadrature demodulation where the in-phase (I) component of the demodulated current is in phase with the complex admittance of the circuit and the quadrature (Q) component is orthogonal to I. Observed excess current noise in the Q component is consistent with fluctuations in the resonant frequency. This noise has been shown to be non-orthogonal to the phase of the detector’s responsivity. We present a detailed analysis of the phase of responsivity of the TES and noise sources in our DfMux readout system. Further, we investigate how modifications to the TES operating resistance and bias frequency can affect the phase of noise relative to the phase of the detector responsivity, using data from Simons Array to evaluate our predictions. We find that both the phase of responsivity and phase of noise are functions of the two tuning parameters, which can be purposefully selected to maximize signal-to-noise (SNR) ratio.

47 OTHER INSTRUMENTATION↗

DOE OSTI2019

Application of deconvolution to recover frequency-domain multiplexed detector pulses

Multiplexing of radiation detectors reduces the number of readout channels, which in turn reduces the number of digitizer input channels for data acquisition. We recently demonstrated frequency domain multiplexing (FDM) of pulse mode radiation detectors using a resonator that converts the detector signal into a damped sinusoid by convolution. The detectors were given unique “tags” by the oscillation frequency of each resonator. The charge collected and the time-of-arrival of the detector pulse were estimated from the corresponding resonator output in the frequency domain. In this paper, we demonstrate a new method to recover the detector pulse from the damped sinusoidal output by deconvolution. Deconvolution converts the frequency-encoded detector signal back to the original detector pulse. We have developed a new prototype FDM system to multiplex organic scintillators based on convolution and deconvolution. Using the new prototype, the charge collected under the anode pulse can be estimated from the recovered pulse with an uncertainty of about 4.4 keVee (keV electron equivalent). The time-of-arrival can be estimated from the recovered pulse with an uncertainty of about 102 ps. We also used a CeBr3 inorganic scintillator to measure the Cs-137 gamma spectrum using the recovered pulses and found a standard deviation of 13.8 keV at 662 keV compared to a standard deviation of 13.5 keV when the original pulses were used. Coincidence measurements with Na-22 using the deconvolved pulses resulted in a timing uncertainty of 617 ps compared to an uncertainty of 603 ps using the original pulses. Pulse shape discrimination was also performed using Cf-252 source and EJ-309 organic scintillator pulses recovered by deconvolution. In conclusion, a figure of merit value of 1.08 was observed when the recovered pulses were used compared to 1.2 for the original pulses.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

DOE OSTI2013

Cryogenic on-chip multiplexer for the study of quantum transport in 256 split-gate devices

We present a multiplexing scheme for the measurement of large numbers of mesoscopic devices in cryogenic systems. The multiplexer is used to contact an array of 256 split gates on a GaAs/AlGaAs heterostructure, in which each split gate can be measured individually. The low-temperature conductance of split-gate devices is governed by quantum mechanics, leading to the appearance of conductance plateaux at intervals of 2e{sup 2}/h. A fabrication-limited yield of 94% is achieved for the array, and a “quantum yield” is also defined, to account for disorder affecting the quantum behaviour of the devices. The quantum yield rose from 55% to 86% after illuminating the sample, explained by the corresponding increase in carrier density and mobility of the two-dimensional electron gas. The multiplexer is a scalable architecture, and can be extended to other forms of mesoscopic devices. It overcomes previous limits on the number of devices that can be fabricated on a single chip due to the number of electrical contacts available, without the need to alter existing experimental set ups.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

DOE OSTI2026

Zero-added-loss entanglement multiplexing using time-bin spectral shearing

High-quality quantum communications that enable important capabilities, such as distributed quantum computing and sensing, will require quantum repeaters for providing high-quality entanglement. To realize high-rate heralded entanglement for quantum repeaters, Chen et al . [Phys. Rev. Appl. 19 , 054029 (2023)] proposed a scheme for heralded-multiplexed generation of quasideterministic entangled photon pairs, called zero-added-loss multiplexing (ZALM). Here, we propose a design of the ZALM source using time-bin entanglement and spectral shearing. Additionally, we provide an analysis of experimentally relevant spectral-shearing parameters to optimize the spectral multiplexing. Moreover, we experimentally verify the compatibility of time-bin pulses and spectral shearing, as supported by observation of no appreciable phase shift when the same shearing is applied to both time bins. These results expand the benefits of applying a ZALM source to time-bin entanglement use cases. Moreover, more fully demonstrating time-bin and spectral shearing compatibility clears a path toward a broader use of spectral shearing that provides a deterministic frequency shift of high utility.

entanglement production↗

DOE OSTI2026

Readout Noise of Digital Frequency Multiplexed TES Detectors for CUPID

The superconducting transition-edge sensor (TES) detectors have been the standard in cosmic microwave background (CMB) experiments for almost two decades and are now being adapted for use in nuclear physics, such as neutrinoless double beta decay searches. In this article, we focus on a new high-bandwidth frequency multiplexed TES readout system developed for CUPID, a neutrinoless double beta decay experiment that will replace CUORE. In order to achieve the high energy resolution requirements for CUPID, the readout noise of the system must be kept to a minimum. Low TES operating resistance and long wiring between the readout SQUID and the warm electronics are needed for CUPID, prompting a careful consideration of the design parameters of this application of frequency multiplexing. In this work, we characterize the readout noise of the newly designed frequency multiplexed TES readout system for CUPID and construct a noise model to understand it. Here, we find that current sharing between the SQUID coil impedance and other branches of the circuit, as well as the long output wiring, worsen the readout noise of the system. To meet noise requirements, a SQUID with a low input inductance, high transimpedance, and/or low dynamic impedance is needed, and the wiring capacitance should be kept as small as possible. Alternatively, the option of adding a cryogenic low-noise amplifier at the output of the SQUID should be explored.

CUPID↗

DOE OSTI2021

Multiplexing of frequency-modulation spectroscopy by spread-spectrum codes, demonstrated in continuous-wave LIDAR

Frequency-modulation spectroscopy (FMS) is generally suited to code-division multiplexing, and we demonstrate that capacity in a form of continuous-wave LIDAR, utilizing a sharp CO 2 absorption transition at 1.6 µm in simple ranging setups. The approach retains the advantages of FMS, including coherent detection and good rejection of broad absorption backgrounds. Extensions of this multiplexed approach to the continuous, simultaneous detection of several transitions would come by transmitting an encoded combination of frequency-modulated carriers, each tuned to detect a unique absorption transition. Signal analysis at the receiver involves a simple process of de-multiplexing that, in a general application, reveals targets at various distances and the absorption-related FMS signals in between.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

DOE OSTI2023

Multiplexed photoinjector optimization for high-repetition-rate free-electron lasers

The multiplexing capabilities of superconducting X-ray free-electron lasers (FELs) have gained much attention in recent years. The demanding requirements for photon properties from multiple undulator lines necessitate more flexible beam manipulation techniques to achieve the goal of “beam on demand”. In this paper, we investigate a multiplexed configuration for the photoinjector of high-repetition-rate FELs that aims to simultaneously provide low-emittance electron beams of different charges. A parallel, multi-objective genetic algorithm is implemented for the photoinjector parameter optimization. The proposed configuration could drastically enhance the flexibility of beam manipulation to improve multiplexing capabilities and realize the full potential of the facility.

47 OTHER INSTRUMENTATION↗

DOE OSTI2022

Multiplexed Readout for an Experiment with a Large Number of Channels Using Single-Electron Sensitivity Skipper-CCDs

This paper presents the implementation of a multiplexed analog readout electronics system that can achieve single-electron counting using Skipper-CCDs with non-destructive readout. The proposed system allows the best performance of the sensors to be maintained, with sub-electron noise-level operation, while maintaining low-bandwidth data transfer, a minimum number of analog-to-digital converters (ADC) and low disk storage requirement with zero added multiplexing time, even for the simultaneous operation of thousands of channels. These features are possible with a combination of analog charge pile-up, sample and hold circuits and analog multiplexing. The implementation also aims to use the minimum number of components in circuits to keep compatibility with high-channel-density experiments using Skipper-CCDs for low-threshold particle detection applications. Performance details and experimental results using a sensor with 16 output stages are presented along with a review of the circuit design considerations.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

NASA NTRS2021

Mitigation of Finite Bandwidth Effects in Time-Division-Multiplexed SQUID Readout of TES Arrays

Time division multiplexing (TDM) is being developed as the readout technology of the X-ray integral field unit (X-IFU), a 3,168-pixel X-ray transition-edge sensor (TES) imaging spectrometer that is part of the European Space Agency's Athena satellite mission. Recent improvements in the low X-ray event count rate performance of TDM have been driven by increases in multiplexer bandwidth and the mitigation of settling transients. These methods and design changes have improved the 32-row multiplexed resolution of a NASA LPA 2.5a array from an initial (2.73 ± 0.03) eV to (1.97 ± 0.01) eV resolution at 5.9 keV. We discuss these recent advances in TDM readout, which have been implemented in an 8-column × 32-row spectrometer that will be deployed at the Lawrence Livermore National Laboratory electron beam ion trap (EBIT) facility, and present a model that will inform the design of future systems.

Transition-edge sensors↗

NASA NTRSDate not supplied

Automated Addressing Failure Detection for Multiplexer Systems

Multiplexers are electronic devices which select between several input signals and deliver an output signal. Also known as data selectors or mux, multiplexers are commonly used in circuit design to provide signal switching, simplify hardware and manufacturing, and decrease cost. Systems which use a digital mux as a switch or selector are vulnerable to events called addressing failures, arising in hardware or software. An addressing failure results in the system requesting, or the mux delivering, a data signal other than the one intended. The unintended use of this erroneous signal may lead to system-level failures. This paper discusses a novel method of automatic detection for addressing failures, utilizing multiplexer channelization and a monitoring algorithm.

multiplexer↗

DOE OSTI2022

The Simons Observatory: Magnetic Shielding Measurements for the Universal Multiplexing Module

The Simons Observatory (SO) includes four telescopes that will measure the temperature and polarization of the cosmic microwave background using over 60,000 highly sensitive transition-edge bolometers (TES). These multichroic TES bolometers are read out by a microwave RF SQUID multiplexing system with a multiplexing factor of 910. Given that both TESes and SQUIDs are susceptible to magnetic field pickup and that it is hard to predict how they will respond to such fields, it is important to characterize the magnetic response of these systems empirically. This information can then be used to limit spurious signals by informing magnetic shielding designs for the detectors and readout. This paper focuses on measurements of magnetic pickup with different magnetic shielding configurations for the SO universal multiplexing module (UMM), which contains the SQUIDs, associated resonators, and TES bias circuit. The magnetic pickup of a prototype UMM was tested under three shielding configurations: no shielding (copper packaging), aluminum packaging for the UMM, and a tin/lead-plated shield surrounding the entire dilution refrigerator 100 mK cold stage. We also present measurements of the pickup in the UMM when aluminum feedhorns are installed. The measurements show that the aluminum packaging outperforms the copper packaging by a shielding factor of 8-10, and adding the tin/lead-plated 1K shield further increases the relative shielding factor in the aluminum configuration by 1-2 orders of magnitude. Furthermore, the addition of feedhorns provides a factor of 30 improvement when the tin/lead shield is not installed and a factor of 5 improvement when it is.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

DOE OSTI2019

Determination of Gas-Phase Ion Mobility Coefficients Using Voltage Sweep Multiplexing

In a standard single averaged, drift tube ion mobility spectrometry (IMS) experiment, typically less than 1% of the ions are utilized, with the rest of the ions neutralizing on a closed ion gate or ion optic element. Though some efforts at lower pressures (e.g., 4 Torr) have been made to address this issue by concentrating ions prior to release into a drift cell, the ion current reaching the detector during an IMS experiment is often diminished due to this lower duty cycle. Additionally, when considering the temporal nature of the drift tube IMS experiment and the trajectory of IMS towards higher resolution separations and lower duty cycles, increased detector sampling rates are another factor also which further necessitates new modes of conducting the IMS experiment. Placing this trend in context with ion mobility-mass spectrometry instruments (IM-MS), there are numerous types of mass spectrometers that are simply incompatible with the single averaged ion mobility spectrometry experiments due to timing incompatibilities (i.e., ion traps are an order of magnitude slower than the IMS experiment). However, by utilizing a dual gate ion mobility spectrometer for ion multiplexing, ion utilization efficiency can be significantly increased while creating a measurement signal that can be recorded at low sampling rates. In this work, we present the fundamental theory and first results from proof-of-concept measurements using a new type of ion multiplexing that relies on changing the electric field within the drift cell during the course of an experiment while simultaneously opening the ion gates at a constant frequency. For brevity, this mode is termed voltage sweep multiplexing (VSM). Key variables for this type of experiment are discussed and verified with measurements from traditional signal averaged experiments. .

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

DOE OSTI2018

Accurate, Sensitive, and Precise Multiplexed Proteomics Using the Complement Reporter Ion Cluster

We present that quantitative analysis of proteomes across multiple time points, organelles, and perturbations is essential for understanding both fundamental biology and disease states. The development of isobaric tags (e.g. TMT) have enabled the simultaneous measurement of peptide abundances across several different conditions. These multiplexed approaches are promising in principle because of advantages in throughput and measurement quality. However, in practice existing multiplexing approaches suffer from key limitations. In its simple implementation (TMT-MS2), measurements are distorted by chemical noise leading to poor measurement accuracy. The current state-of-the-art (TMT-MS3) addresses this, but requires specialized quadrupole-iontrap-Orbitrap instrumentation. The complement reporter ion approach (TMTc) produces high accuracy measurements and is compatible with many more instruments, like quadrupole-Orbitraps. However, the required deconvolution of the TMTc cluster leads to poor measurement precision. Here, we introduce TMTc+, which adds the modeling of the MS2-isolation step into the deconvolution algorithm. The resulting measurements are comparable in precision to TMT-MS3/MS2. The improved duty cycle, and lower filtering requirements make TMTc+ more sensitive than TMT-MS3 and comparable with TMT-MS2. At the same time, unlike TMT-MS2, TMTc+ is exquisitely able to distinguish signal from chemical noise even outperforming TMT-MS3. Lastly, we compare TMTc+ to quantitative label-free proteomics of total HeLa lysate and find that TMTc+ quantifies 7.8k versus 3.9k proteins in a 5-plex sample. At the same time the median coefficient of variation improves from 13% to 4%. Furthermore, TMTc+ advances quantitative proteomics by enabling accurate, sensitive, and precise multiplexed experiments on more commonly used instruments.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

DOE OSTI2021

Excitation spectral microscopy for highly multiplexed fluorescence imaging and quantitative biosensing

The multiplexing capability of fluorescence microscopy is severely limited by the broad fluorescence spectral width. Spectral imaging offers potential solutions, yet typical approaches to disperse the local emission spectra notably impede the attainable throughput. Here we show that using a single, fixed fluorescence emission detection band, through frame-synchronized fast scanning of the excitation wavelength from a white lamp via an acousto-optic tunable filter, up to six subcellular targets, labeled by common fluorophores of substantial spectral overlap, can be simultaneously imaged in live cells with low (~1%) crosstalks and high temporal resolutions (down to ~10 ms). The demonstrated capability to quantify the abundances of different fluorophores in the same sample through unmixing the excitation spectra next enables us to devise novel, quantitative imaging schemes for both bi-state and Förster resonance energy transfer fluorescent biosensors in live cells. We thus achieve high sensitivities and spatiotemporal resolutions in quantifying the mitochondrial matrix pH and intracellular macromolecular crowding, and further demonstrate, for the first time, the multiplexing of absolute pH imaging with three additional target organelles/proteins to elucidate the complex, Parkin-mediated mitophagy pathway. Together, excitation spectral microscopy provides exceptional opportunities for highly multiplexed fluorescence imaging. The prospect of acquiring fast spectral images without the need for fluorescence dispersion or care for the spectral response of the detector offers tremendous potential.

59 BASIC BIOLOGICAL SCIENCES↗