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At least 91 records · Page 5

An analysis of job placement patterns of black and non-black male and female undergraduates at the University of Virginia and Hampton Institute

Research questions were proposed to determine the relationship between independent variables (race, sex, and institution attended) and dependent variables (number of job offers received, salary received, and willingness to recommend source of employer contact). The control variables were academic major, grade point average, placement registration, nonemployment activity, employer, and source of employer contact. An analysis of the results revealed no statistical significance of the institution attended as a predictor of job offers or salary, although significant relationships were found between race and sex and number of job offers received. It was found that academic major, grade point average, and source of employer contact were more useful than race in the prediction of salary. Sex and nonemployment activity were found to be the most important variables in the model. The analysis also indicated that Black students received more job offers than non-Black students.

Anderson, A. F.↗

Effect of potassium depletion in normal males - An Apollo 15 simulation

In the course of Apollo 15, physiologic abnormalities, manifested by ectopic activity on the ECG and unusual alterations in exercise tolerance, occurred in the crew of the Lunar Excursion Module. These were associated with decreases in total body potassium, measured by K-42, of 10% and 15%. The possibility of inadequate potassium (K+) intake existed. A simulation study was performed prior to Apollo 16, corresponding in duration to Apollo 15. Subjects endured the same sleep aberrations and caloric expenditure as the Apollo 15 astronauts. Subjects consumed a diet containing only 15 mEq/d of K+ during the entire 12 days of absolute bedrest. Study implications and reasons for discrepancies between K+ loss measured by balance techniques and K-42 are reviewed.

Hyatt, K. H.↗

Computer analysis of femoral angiograms for evaluation of atherosclerosis in post-infarct males-clinical correlates

Femoral artery atheromatous lesions were studied and their changes as a measure of therapeutic effectiveness were assessed. The incidence of coronary risk factors in 100 patients was determined. Abnormal cholesterol was present in 42 percent, abnormal triglycerides in 66 percent, abnormal intravenous glucose tolerance test in 52 percent, judged from a K value of .9 or less by the technique of Wahlbert. A history of high blood pressure was present in 32 percent. Smoking was one of the most common factors.

Sanmarco, M. E.↗

Increase of plasma renin activity in male and female rabbits subjected to dysbaric conditions

The renin-angiotensin-aldosterone system may be implicated in hemodynamic alterations occurring in dysbaric disorders. This report concerns changes in plasma renin activity (PRA) induced by exposure of rabbits to a compression-decompression schedule that does not normally produce clinical manifestations of decompression sickness. The results revealed a significant increase in PRA in 19 of 23 animals following dysbaric exposure. Mean PRA rose from 1.18 ng ang I/ml hr (preexposure) to 2.40 ng ang I/ml hr (postexposure). The increase was particularly pronounced in female animals (217 percent). Asymptomatic intravascular gas bubbles (silent bubbles) were detected by gross or microscopic examination in the majority of the animals. Renin elaboration and secretion in asymptomatic dysbaric exposures may be mediated by bradykinin and/or prostaglandins released or activated in a chain reaction triggered by silent gas bubbles. This hypothesis is also applicable to increased PRA in altitude decompression. Alternatively elevation of PRA may result from decreased renal perfusion when dysbaric disorders are complicated by significant hypovolemia.

Chryssanthou, C.↗

Effects of simulated weightlessness and sympathectomy on maximum VO2 of male rats

The effects of simulated weightlessness (hind-limb suspension) and chemical sympathectomy (by repeated injections with guanethidine sulfate) on the maximum oxygen consumption (VO2 max) of female rats were investigated in rats assigned for 14 days to one of three groups: a head-down hind-limb suspension, a horizontal suspension with hind limbs weight bearing, or the caged control. The VO2 max values were assessed by having rats run on a treadmill enclosed in an airtight chamber. The hind-limb-suspended sympathectomized rats were found to exhibit shorter run times and lower mechanical efficiencies, compared to their presuspension values or the values from saline-injected suspended controls. On the other hand, the suspended sympathectomized rats did not demonstrate a decrease in the VO2 max values that was observed in saline-injected controls.

Woodman, C. R.↗

Effects of chronic elevated levels of CO2 on the concentration of blood cellular elements and plasma corticosterone in the male rat

The mean CO2 concentration on the Space Shuttle is 0.3% and has reached 0.7%, for extended periods of time. Following space flight, it has been shown that both humans and animals have significant changes in red blood cell counts (RBC) and white blood cell counts (WBC). In other studies, where no significant change did occur in the total WBC, a significant change did occur in the distribution of WBC. WBC are affected by circulating levels of glucocorticoids, which often increase when animals or humans are exposed to adverse and/or novel stimuli (e.g. elevated CO2 levels or weightlessness). The purpose of this study was to determine if elevations in CO2 concentration produce changes in total WBC and/or their distribution.

Alexander, R. A.↗

Baseline Assumptions and Ersatz Waste Streams for Partial Gravity Habitats with Mobile Female and Male Crew

Effective and reliable water management and recovery systems will be required to support human missions beyond the low Earth orbit (LEO) of the International Space Station (ISS). Lunar and Mars surface missions will introduce new challenges to managing water and associated waste streams from mobile crew members who are transiting between up to six living shelters in extreme environmental conditions under a range of gravity conditions. A review of baseline assumptions for the human activities and associated air and water cycles in and between transit vehicle, orbiting station, lander-ascent vehicle, surface habitat, pressurized rover, and suits is conducted. The paper updates ersatz formulations and water flow rates for the main liquid water waste streams of urine, humidity condensate, hygiene, and laundry. Emphasis is placed on the metabolic emissions partitioning between the six vehicles during a design reference mission scenario. Ersatz to represent menses are reviewed.

Dean L Muirhead↗

Baseline Assumptions and Ersatz Waste Streams for Partial Gravity Habitats with Mobile Female and Male Crew

Effective and reliable water management and recovery systems will be required to sup-port human missions beyond the low Earth orbit (LEO) of the International Space Station (ISS). Lunar and Mars surface missions will introduce new challenges to managing water and associated waste streams from mobile crew members who will be living in up to six shelters in extreme environmental conditions under a range of gravity conditions. A review of baseline assumptions for the human activities and associated air and water cycles in and between the transit vehicle, orbiting station, lander-ascent vehicle, surface habitat, pressurized rover, and suits is conducted. The paper reviews ersatz formulations and water flow rates for the main liquid water waste streams of urine, humidity condensate, hygiene, and laundry. Emphasis is placed on the metabolic emissions partitioning between the six habitat elements and the lunar exosphere during a design reference mission scenario.

Water Ersatz Habitat↗

Baseline Assumptions and Ersatz Waste Streams for Partial Gravity Habitats with Mobile Female and Male Crew

Effective and reliable water management and recovery systems will be required to sup-port human missions beyond the low Earth orbit (LEO) of the International Space Station (ISS). Lunar and Mars surface missions will introduce new challenges to managing water and associated waste streams from mobile crew members who will be living in up to six shelters in extreme environmental conditions under a range of gravity conditions. A review of baseline assumptions for the human activities and associated air and water cycles in and between the transit vehicle, orbiting station, lander-ascent vehicle, surface habitat, pressurized rover, and suits is conducted. The paper reviews ersatz formulations and water flow rates for the main liquid water waste streams of urine, humidity condensate, hygiene, and laundry. Emphasis is placed on the metabolic emissions partitioning between the six habitat elements and the lunar exosphere during a design reference mission scenario.

Water Ersatz Habitat↗

Time course of epiphyseal growth plate fusion in rat tibiae

Although the rat is the most common animal model used in studying osteoporosis, it is often used inappropriately. Osteoporosis is a disease that most commonly occurs in humans long after growth plate fusion with the associated cessation of longitudinal bone growth, but there has been a question as to when or to what extent the rat growth plate fuses. To investigate this question, we used microcomputed X-ray tomography, at voxel resolutions ranging from (5.7 micro m)(3) to (11 micro m)(3), to image the proximal epiphyseal growth plates of both male (n = 19) and female (n = 15) rat tibiae, ranging in age from 2 to 25 months. The three-dimensional images were used to evaluate fusion of the epiphyseal growth plate by quantitating the amount of cancellous bone that has bridged across the growth plate. The results suggest that the time course of fusion of the epiphyseal growth plate follows a sigmoidal pattern, with 10% of the maximum number of bridges having formed by 3.9 months in the male tibiae and 5.8 months in the female tibiae, 50% of the maximum number of bridges having formed by 5.6 months in the male tibiae and 5.9 months in the female tibiae, and 90% of the total maximum of bridges have formed by 7.4 months for the males and 6.5 months for the females. The total volume of bridges per tibia at the age at which the maximum number of bridges per tibia has first formed is 0.99 mm(3)/tibia for the males and 0.40 mm(3)/tibia for the females. After the maximum number of bridges (-290 for females, -360 for males) have formed the total volume of bridges per tibia continues to increase for an additional 7.0 months in the males and 17.0 months for the females until they reach maximum values (-1.5 mm(3)/tibia for the males and -2.2 mm(3)/tibia for the females).

NASA Discipline Cell Biology↗