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The POEMMA (Probe of Extreme Multi-Messenger Astrophysics) Observatory

The Probe Of Extreme Multi-Messenger Astrophysics (POEMMA) is designed to accurately observe ultra-high-energy cosmic rays (UHECRs) and cosmic neutrinos from space with sensitivity over the full celestial sky. POEMMA will observe the air fluorescence produced by extensive air showers (EASs) from UHECRs and potentially UHE neutrinos above 20 EeV. Additionally, POEMMA has the ability to observe the Cherenkov signal from upward-moving EASs induced by Earth-interacting tau neutrinos above 20 PeV. The POEMMA spacecraft are designed to quickly re-orientate to follow up transient neutrino sources and obtain currently unparalleled neutrino flux sensitivity. Developed as a NASA Astrophysics Probe-class mission, POEMMA consists of two identical satellites flying in loose formation in 525 km altitude orbits. Each POEMMA instrument incorporates a wide field-of-view (45°) Schmidt telescope with an optical collecting area of over 6 sq. m. The hybrid focal surface of each telescope includes a fast (1 μs) near-ultraviolet camera for EAS fluorescence observations and an ultrafast (10 ns) optical camera for Cherenkov EAS observations. In a 5-year mission, POEMMA will provide measurements that open new multi-messenger windows onto the most energetic events in the universe, enabling the study of new astrophysics and particle physics at these extreme energies.

A. V. Olinto↗

The POEMMA (Probe of Extreme Multi-Messenger Astrophysics)Observatory

The Probe Of Extreme Multi-Messenger Astrophysics (POEMMA) is designed to accurately observe ultra-high-energy cosmic rays (UHECRs) and cosmic neutrinos from space with sensitivity over the full celestial sky. POEMMA will observe the air fluorescence produced by extensive air showers (EASs) from UHECRs and potentially UHE neutrinos above 20 EeV. Additionally, POEMMA has the ability to observe the Cherenkov signal from upward-moving EASs induced by Earth-interacting tau neutrinos above 20 PeV. The POEMMA spacecraft are designed to quickly re-orientate to follow up transient neutrino sources and obtain currently unparalleled neutrino flux sensitivity. Developed as a NASA Astrophysics Probe-class mission, POEMMA consists of two identical satellites flying in loose formation in 525 km altitude orbits. Each POEMMA instrument incorporates a wide field-of-view (45°) Schmidt telescope with an optical collecting area of over 6 m2. The hybrid focal surface of each telescope includes a fast (1 μs) near-ultraviolet camera for EAS fluorescence observations and an ultrafast (10 ns) optical camera for Cherenkov EAS observations. In a 5-year mission, POEMMA will provide measurements that open new multi-messenger windows onto the most energetic events in the universe, enabling the study of new astrophysics and particle physics at these extreme energies.

A. V. Olinto↗

Data Analysis Challenges for Multi-Messenger Astrophysics

Recent multi-messenger observations of gravitational-wave and high-energy neutrino sources together with electromagnetic signatures have opened new ways of observing the Universe. These promise a future in which physics and astronomy will be advanced by combining observations and data from across the electromagnetic spectrum with gravitational waves and neutrinos. We consider the challenges the field is facing in fully utilizing data for multi-messenger astrophysics. Such data come from heterogeneous detector networks and standards, and their analysis is often time-critical to guide further observations. In this area, science capabilities depend on the interplay among observation, theory and computational/modeling work. Advances in data science and computing present additional opportunities and considerations in analyzing such data. We invited ADASS participants to a Birds of a Feather session to engage in discussion on the challenges and opportunities in data analysis for multimessenger astrophysics.

Peter S Shawhan↗

The NASA Multi-Messenger Astrophysics Science Support Center (MOSSAIC)*

The era of multi-messenger astrophysics has arrived, leading to key new discoveries and revealing a need for coordination, collab-oration, and communication between world-wide communities using ground and space-based facilities. To fill these critical needs,NASA’s Goddard Space Flight Center and Marshall Space Flight Center are jointly proposing to establish a virtual Multi-MessengerAstrophysics Science Support Center that focuses entirely on community-directed services. In this article, we describe the baselineplan for the virtual Support Center which will position the community and NASA as an Agency to extract maximum science frommulti-messenger events, leading to new breakthroughs and fostering increased coordination and collaboration.

R M Sambruna↗

Chromium on Mercury: New Results From the MESSENGER X-Ray Spectrometer and Implications for the Innermost Planet’s Geochemical Evolution

Mercury, the innermost planet, formed under highly reduced conditions, based mainly on surface Fe, S, and Si abundances determined from MESSENGER mission data. The minor element Cr may serve as an independent oxybarometer but only very limited Cr data have been previously reported for Mercury. We report Cr/Si abundances across Mercury's surface based on MESSENGER X-Ray Spectrometer data throughout the spacecraft's orbital mission. The heterogeneous Cr/Si ratio ranges from 3.6 × 10 -5 in the Caloris Basin to 0.0012 within the high-magnesium region, with an average southern hemisphere value of 0.0008 (corresponding to about 200 ppm Cr). Absolute Cr/Si values have systematic uncertainty of at least 30%, but relative variations are more robust. By combining experimental Cr partitioning data along with planetary differentiation modeling, we find that if Mercury formed with bulk chondritic Cr/Al, Cr must be present in the planet's core and differentiation must have occurred at log ƒO 2 in the range of IW-6.5 to IW-2.5 in the absence of sulfides in its interior and a range of IW-5.5 to IW-2 with an FeS layer at the core-mantle boundary. Models with large fractions of Mg-Ca-rich sulfides in Mercury's interior are more compatible with moderately reducing conditions (IW-5.5 to IW-4) owing to the instability of Mg-Ca-rich sulfides at elevated ƒO 2 . These results indicate that if Mercury differentiated at a log ƒO 2 lower than IW-5.5, the presence of sulfides whether in the form of a FeS layer at the top of the core or Mg-Ca-rich sulfides within the mantle would be unlikely.

Larry R. Nittler↗

ACROSS: Enabling Time Domain and Multi-Messenger Astrophysics

The U.S. Astro2020 Decadal Survey recommended an investment in Time Domain and Multi-Messenger Astrophysics (TDAMM) as the top-priority sustaining activity in space for the coming decade. One aspect of NASA’s response to this rec-ommendation is a pilot project, the Astrophysics Cross-Observatory Science Support (ACROSS) Initiative, designed to provide support to both missions and observers as they pursue TDAMM science. In this talk, we present our observations of needs in the community and initial plans for ACROSS activities, including services to facilitate and improve cross-mission follow-up planning and execution; a multi-messenger web portal with links to existing mission resources, community tools, and information tar-geted for TDAMM General Observers; development of "Smart Target of Opportunity submission page" proof-of-concepts; and ongoing development of a potential TDAMM general observing competitive grant solicitation. While the initial focus has been to en-hance coordination between NASA missions, we are eager to work with ground-based and international partners as well. We invite discussion with both missions and ob-servers to better understand their needs and concerns as ACROSS progresses. Here we present our efforts on the web-portal and API, along with our development to support NASA’s BurstCube mission.

T B Humensky↗

Development of a Platform for High-Resolution Ion Mobility Separations Coupled with Messenger Tagging Infrared Spectroscopy for High-Precision Structural Characterizations

The ability to uniquely identify a compound requires highly precise and orthogonal measurements. Here we describe a newly developed analytical platform that integrates high resolution ion mobility and cryogenic vibrational ion spectroscopy for high-precision structural characterizations. This platform allows for the temporal separation of isomeric/isobaric ions and provides a highly sensitive description of the ion’s adopted geometry in the gas phase. The combination of these orthogonal structural measurements yields precise descriptors that can be used to resolve between and confidently identify highly similar ions. The unique benefits of our instrument, which integrates a structures for lossless ion manipulations ion mobility (SLIM IM) device with messenger tagging infrared spectroscopy, include the ability to perform high-resolution ion mobility separations and to record the IR spectra of all ions simultaneously. The SLIM IM device, with its 13 m separation path length, allows for multipass experiments to be performed for increased resolution as needed. It is integrated with an Agilent qTOF MS where the collision cell was replaced with a cryogenically held (30 K) TW-SLIM module. The cryo-SLIM is operated in a novel manner that allows ions to be streamed through the device and collisionally cooled to a temperature where they can form noncovalently bound N 2 complexes that are maintained as they exit the device and are detected by the TOF mass analyzer. The instrument can be operated in two modes: IMS+IR where the IR spectra for mobility-selected ions can be recorded and IR-only mode where the IR spectra for all mass-resolved ions can be recorded. In IR-only mode, IR spectra (400 cm –1 spectral range) can be recorded in as short as 2 s for high throughput measurements. Further, this work details the construction of the instrument and modes of operation. It provides initial benchmarking of CCS and IR measurements to demonstrate the utility of this instrument for targeted and untargeted approaches.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Full Scale Drag Tests on Various Parts of Sperry Messenger Airplane

The drag of a Sperry Messenger airplane with the wings removed, and also the drag of its various component parts, was measured in the 20-foot air stream of the N.A.C.A. propeller research tunnel at air speeds from 50 to 100 m.p.h. It was found that the three-cylinder radial air-cooled engine nearly doubled the drag of the bare fuselage, and the drag of the landing gear was about the same as that of the fuselage and engine combined.

AIRPLANES - WIND TUNNEL TESTS DRAG TESTS - SPERRY ↗

Characterization and distribution of a maize cDNA encoding a peptide similar to the catalytic region of second messenger dependent protein kinases

Maize (Zea mays) roots respond to a variety of environmental stimuli which are perceived by a specialized group of cells, the root cap. We are studying the transduction of extracellular signals by roots, particularly the role of protein kinases. Protein phosphorylation by kinases is an important step in many eukaryotic signal transduction pathways. As a first phase of this research we have isolated a cDNA encoding a maize protein similar to fungal and animal protein kinases known to be involved in the transduction of extracellular signals. The deduced sequence of this cDNA encodes a polypeptide containing amino acids corresponding to 33 out of 34 invariant or nearly invariant sequence features characteristic of protein kinase catalytic domains. The maize cDNA gene product is more closely related to the branch of serine/threonine protein kinase catalytic domains composed of the cyclic-nucleotide- and calcium-phospholipid-dependent subfamilies than to other protein kinases. Sequence identity is 35% or more between the deduced maize polypeptide and all members of this branch. The high structural similarity strongly suggests that catalytic activity of the encoded maize protein kinase may be regulated by second messengers, like that of all members of this branch whose regulation has been characterized. Northern hybridization with the maize cDNA clone shows a single 2400 base transcript at roughly similar levels in maize coleoptiles, root meristems, and the zone of root elongation, but the transcript is less abundant in mature leaves. In situ hybridization confirms the presence of the transcript in all regions of primary maize root tissue.

NASA Program Space Biology↗

Mechanical stimulation of skeletal muscle generates lipid-related second messengers by phospholipase activation

Repetitive mechanical stimulation of cultured avian skeletal muscle increases the synthesis of prostaglandins (PG) E2 and F2 alpha which regulate protein turnover rates and muscle cell growth. These stretch-induced PG increases are reduced in low extracellular calcium medium and by specific phospholipase inhibitors. Mechanical stimulation increases the breakdown rate of 3H-arachidonic acid labelled phospholipids, releasing free 3H-arachidonic acid, the rate-limiting precursor of PG synthesis. Mechanical stimulation also increases 3H-arachidonic acid labelled diacylglycerol formation and intracellular levels of inositol phosphates from myo-[2-3H]inositol labelled phospholipids. Phospholipase A2 (PLA2), phosphatidylinositol-specific phospholipase C (PLC), and phospholipase D (PLD) are all activated by stretch. The stretch-induced increases in PG production, 3H-arachidonic acid labelled phospholipid breakdown, and 3H-arachidonic acid labelled diacylglycerol formation occur independently of cellular electrical activity (tetrodotoxin insensitive) whereas the formation of inositol phosphates from myo-[2-3H]inositol labelled phospholipids is dependent on cellular electrical activity. These results indicate that mechanical stimulation increases the lipid-related second messengers arachidonic acid, diacylglycerol, and PG through activation of specific phospholipases such as PLA2 and PLD, but not by activation of phosphatidylinositol-specific PLC.

NASA Discipline Number 40-40↗

Parathyroid hormone induces c-fos and c-jun messenger RNA in rat osteoblastic cells

PTH is a potent regulator of osteoblast gene expression, yet the nuclear events that mediate PTH action are poorly understood. We were interested in identifying immediate early genes which may regulate PTH-altered gene expression in the osteoblast. Therefore, we examined the effects of PTH on c-fos and c-jun gene expression in a rat osteoblastic cell line (UMR 106-01). Under control conditions, c-fos and c-jun mRNAs were present at low basal levels. After PTH treatment, c-fos mRNA abundance dramatically increased, with a maximal and transient response at 30 min. PTH also stimulated an increase in c-jun mRNA, but in a biphasic manner, with maximal levels at 30 min and 2 h. These responses were dose dependent, not altered by cotreatment with the protein synthesis inhibitor cycloheximide, and preceded PTH-induced expression of matrix metallo-proteinase-1 mRNA. Nuclear run-on assays demonstrated an increased rate of c-fos and c-jun transcription after PTH exposure. To determine the signal transduction pathways involved, second messenger analogs were tested for their ability to mimic the effects of PTH. 8-Bromo-cAMP and phorbol 12-myristate 13-acetate (PMA) caused increases in the abundance of c-fos and c-jun transcripts. Ionomycin had no effect on the expression of these genes. Pretreatment of the cells with PMA resulted in a decrease in basal c-jun expression, but did not alter the PTH-mediated increase in c-fos, c-jun, or matrix metalloproteinase-1 mRNAs.(ABSTRACT TRUNCATED AT 250 WORDS).

Non-NASA Center↗

Chemical Heterogeneity on Mercury's Surface Revealed by the MESSENGER X-ray Spectrometer

We present the analysis of 205 spatially resolved measurements of the surfacecomposition of Mercury from MESSENGERs X-Ray Spectrometer. The surfacefootprints of these measurements are categorized according to geological terrain. Northernsmooth plains deposits and the plains interior to the Caloris basin differ compositionallyfrom older terrain on Mercury. The older terrain generally has higher MgSi, SSi, andCaSi ratios, and a lower AlSi ratio than the smooth plains. Mercurys surface mineralogyis likely dominated by high-Mg mafic minerals (e.g., enstatite), plagioclase feldspar, andlesser amounts of Ca, Mg, andor Fe sulfides (e.g., oldhamite). The compositionaldifference between the volcanic smooth plains and the older terrain reflects differentabundances of these minerals and points to the crystallization of the smooth plains from amore chemically evolved magma source. High-degree partial melts of enstatite chondritematerial provide a generally good compositional and mineralogical match for much ofthe surface of Mercury. An exception is Fe, for which the low surface abundance onMercury is still higher than that of melts from enstatite chondrites and may indicate anexogenous contribution from meteoroid impacts.

Chemical heterogeneity↗

MESSENGER and Mariner 10 Flyby Observations of Magnetotail Structure and Dynamics at Mercury

The first (M1), second (M2), and third (M3) MESSENGER flybys of Mercury traversed the planet's magnetotail from 1.25 to 3.25 RM downstream of the planet, where R(sub M) is Mercury's radius (2440 km). The encounters took place under northward, southward, and variable-polarity interplanetary magnetic field (IMF), respectively. The magnetic field strength B in Mercury's magnetotail follows a power law decrease with increasing antisunward distance ∣X∣, B approximately ∣X∣(sup G), with G varying from -5.4 for northward to -1.6 for southward IMF. Low-latitude boundary layers (LLBLs) containing strong northward magnetic field were detected at the tail flanks during two of the flybys. The observed thickness of the LLBL was 33% and 16% of the radius of the tail during M1 and M3, respectively, but the boundary layer was completely absent during M2. Clear signatures of tail reconnection are evident in the M2 and M3 magnetic field measurements. Plasmoids and traveling compression regions were observed during M2 and M3 with typical durations of approximately 1-3 s, suggesting diameters of approximately 500-1500 km. Overall, the response of Mercury's magnetotail to the steady southward IMF during M2 appeared very similar to steady magnetospheric convection events at Earth, which are believed to be driven by quasi-continuous reconnection. In contrast, the M3 measurements are dominated by tail loading and unloading events that resemble the large-scale magnetic field reconfigurations observed during magnetospheric substorms at Earth.

Magnetotail↗

The Gravity Field, Orientation, and Ephemeris of Mercury from MESSENGER Observations After Three Years in Orbit

We have analyzed three years of radio tracking data from the MESSENGER spacecraft in orbit around Mercury and determined the gravity field, planetary orientation, and ephemeris of the innermost planet. With improvements in spatial coverage, force modeling, and data weighting, we refined an earlier global gravity field both in quality and resolution, and we present here a spherical harmonic solution to degree and order 50. In this field, termed HgM005, uncertainties in low-degree coefficients are reduced by an order of magnitude relative to the earlier global field, and we obtained a preliminary value of the tidal Love number k(sub 2) of 0.451+/-0.014. We also estimated Mercury's pole position, and we obtained an obliquity value of 2.06 +/- 0.16 arcmin, in good agreement with analysis of Earth-based radar observations. From our updated rotation period (58.646146 +/- 0.000011 days) and Mercury ephemeris, we verified experimentally the planet's 3: 2 spin-orbit resonance to greater accuracy than previously possible. We present a detailed analysis of the HgM005 covariance matrix, and we describe some near-circular frozen orbits around Mercury that could be advantageous for future exploration.

MESSENGER↗

New Optical Navigation Results Using Historical MESSENGER Data

This paper describes new optical navigation (OpNav) results obtained by processing previously collected measurements from the MESSENGER mission to Mercury. This project also serves to mature the tools and capabilities of NASA Goddard Space Flight Center (GSFC) in OpNav, using the open source Goddard Image Analysis and Navigation Tool (GIANT). New navigation measurements are obtained during the Mercury flyby and orbital phases, using OpNav measurements generated by GIANT, and these measurements are compared to predictions. The results obtained provide a set of improvements to be made in navigation tools and will pave the way for future missions to navigate near terrestrial bodies using optical measurements.

Optical Navigation↗

Regional Variations of Mercury's Crustal Density and Porosity From MESSENGER Gravity Data

A new solution of Mercury's gravity field to degree and order 160, named HgM009, is retrieved through a reprocessing of MESSENGER radio science measurements. By combining our latest gravity field with topography data, localized spectral admittance analyses are carried out to investigate Mercury's crustal and lithospheric properties across the northern hemisphere. The measured spectra are compared with admittances predicted by lithospheric flexure models. The localized gravity/topography admittance analyses yield key information on the lateral variations of the bulk density of the upper crust. Elastic and crustal thicknesses are also adjusted in our study, but the local admittance spectra allow us to constrain these parameters only over a few regions. The average bulk density across the observed areas in the northern hemisphere is 2540 ±60 kg m −3 . The crustal porosity is then constrained by using an estimate of the pore-free grain density of surface materials with our measured bulk density. Our estimate of the mean porosity is 14.7 ±1.6 %, which is comparable to, but slightly higher than, the average value measured on the Moon. Larger crustal porosities are observed over heavily cratered regions, suggesting that impact bombardment is the main cause of the crustal porosity.

Mercury's crust↗

Structures of the DarR transcription regulator reveal unique modes of second messenger and DNA binding

The mycobacterial repressor, DarR, a TetR family regulator (TFR), was the first transcription regulator shown to bind c-di-AMP. However, the molecular basis for this interaction and the mechanism involved in DNA binding by DarR remain unknown. Here we describe DarR-c-di-AMP and DarR-DNA structures and complementary biochemical assays. The DarR-c-di-AMP structure reveals a unique effector binding site for a TFR, located between DarR dimer subunits. Strikingly, we show this motif also binds cAMP. The location of the adenine nucleotide binding site between subunits suggests this interaction may facilitate dimerization and hence DNA binding. Indeed, biochemical assays show cAMP enhances DarR DNA binding. Finally, DarR-DNA structures reveal a distinct TFR DNA-binding mechanism involving two interacting dimers on the DNA. Thus, the combined data unveil a newly described second messenger binding motif and DNA binding mode for this important family of regulators.

59 BASIC BIOLOGICAL SCIENCES↗

Multi-messenger dynamic imaging of laser-driven shocks in water using a plasma wakefield accelerator

Understanding dense matter hydrodynamics is critical for predicting plasma behavior in environments relevant to laser-driven inertial confinement fusion. Traditional diagnostic sources face limitations in brightness, spatiotemporal resolution, and in their ability to detect relevant electromagnetic fields. In this work, we present a dual-probe, multi-messenger laser wakefield accelerator platform combining ultrafast X-rays and relativistic electron beams at 1 Hz, to interrogate a free-flowing water target in vacuum, heated by an intense 200 ps laser pulse. This scheme enables high-repetition-rate tracking the evolution of the interaction using both particle types. Betatron X-rays reveal a cylindrically symmetric shock compression morphology assisted by low-density vapor, resembling foam-layer-assisted fusion targets. The synchronized electron beam detects time-evolving electromagnetic fields, uncovering charge separation and ion species differentiation during plasma expansion – phenomena not captured by photons or hydrodynamic simulations. We show that combining both probes provides complementary insights spanning kinetic to hydrodynamic regimes, highlighting the need for hybrid physics models to accurately predict fusion-relevant plasma behavior.

imaging techniques↗