Stochastic compartmental analysis - Some applications and examples of estimation in a pulse labelled system
Stochastic compartmental analysis with examples of estimation in pulse labelled system
Ellis, W. C.↗
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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.
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Preparation of tumor specific boron compounds. 1: In vitro studies using boron labeled antibodies and elemental boron as neutron targets
In vitro studies using boron-labeled antibodies and elemental boron as neutron target in therapy for tumors and cancer
Hawthorne, M. F.↗
Detection of metabolically produced labeled gas - The Viking Mars Lander.
A qualitative, nonspecific method will test for life on Mars in 1976 by supplying radioactive substrates to samples of the planetary surface material. If microorganisms are present, they may assimilate one or more of the simple labeled compounds and produce radioactive gas. The compounds have been selected on the basis of biological theory and terrestrial results. The measurement of radioactive gas evolved as a function of time constitutes evidence for life. A control performed on a duplicate, but heat sterilized, sample will confirm the biological nature of the results. The shape of the response curve obtained from the viable sample may provide information on the physiological state and generation period of the organisms. Data obtained from a wide variety of terrestrial soils demonstrate a rapid response and high sensitivity for the experiment. Its ability to make comparative studies of soil microorganisms is also demonstrated.
Levin, G. V.↗
Semiautomatic labeling of small wires
Semi-automatic-wire labeling equipment installs heat-shrink identification sleeves on small-diameter wires for moderate-size production runs. Supply reel contains wire of desired diameter and is cut into lengths set on the measuring rolls. Required number of identification sleeves are slipped over wire, which is then placed through sleeve-releasing mechanism. Sleeves are shrunk at 350 degrees F in an infrared oven.
David, L. P.↗
Positron emission reconstruction tomography for the assessment of regional myocardial metabolism by the administration of substrates labeled with cyclotron produced radionuclides
A positron emission transverse tomograph device was developed which provides transaxial sectional images of the distribution of positron-emitting radionuclides in the heart. The images provide a quantitative three-dimensional map of the distribution of activity unencumbered by the superimposition of activity originating from regions overlying and underlying the plane of interest. PETT is used primarily with the cyclotron-produced radionuclides oxygen-15, nitrogen-13 and carbon-11. Because of the participation of these atoms in metabolism, they can be used to label metabolic substrates and intermediary molecules incorporated in myocardial metabolism.
Ter-Pogossian, M. M.↗
A study of various synthetic routes to produce a halogen-labeled traction fluid
Several synthetic routes were studied for the synthesis of the compound 1, 1, 3-trimethyl-1, 3-dicyclohexyl-2 chloropropane. This halogen-labeled fluid would be of use in the study of high traction lubricants under elastohydrodynamic lubrication conditions using infrared emission spectroscopy. The synthetic routes included: dimerization of alpha-methylstyrene, methanol addition to alpha-methylstyrene, a Wittig reaction, and an organometallic approach. Because of steric hindrance and competing reactions, none of these routes were successful.
Jones, W. R., Jr.↗
Software requirements for the study of contextual classifiers and label imperfections
The software requirements for the study of contextual classifiers and imperfections in the labels are presented. In particular, the requirements are described for updating the posteriori probability of the picture element under consideration using information from its local neighborhood, designing the Fisher classifier, and other required routines. Only the necessary equations are given for the development of software.
Chittineni, C. B.↗
Analysis and interpretation of Viking labeled release experimental results
The Viking Labeled Release (LR) life detection experiment on the surface of Mars produced data consistent with a biological interpretation. In considering the plausibility of this interpretation, terrestrial life forms were identified which could serve as models for Martian microbial life. Prominent among these models are lichens which are known to survive for years in a state of cryptobiosis, to grow in hostile polar environments, to exist on atmospheric nitrogen as sole nitrogen source, and to survive without liquid water by absorbing water directly from the atmosphere. Another model is derived from the endolithic bacteria found in the dry Antarctic valleys; preliminary experiments conducted with samples of these bacteria indicate that they produce positive LR responses approximating the Mars results. However, because of the hositility of the Martian environment to life, and the failure to find organics on the surface of Mars, a number of nonbiological explanations were advanced to account for the Viking LR data. A reaction of the LR nutrient with putative surface hydrogen peroxide is the leading candidate. Other possibilities raised include reactions caused by or with ultraviolet irradiation, gamma-Fe2O3, metalloperoxides or superoxides.
Levin, G. V.↗
Polyglutaraldehyde - A new reagent for coupling proteins to microspheres and for labeling cell-surface receptors
Glutaraldehyde polymerized in basic aqueous solutions was found to react with low molecular weight amines, immunoglobulins and hemoglobin. The polyglutaraldehyde was covalently bound to hydrophilic microspheres. The rate of addition of proteins to the polyglutaraldehyde-derivatized microspheres was investigated spectrophotometrically as a function of pH and temperature. The reaction of polyglutaraldehyde was found to be faster than that of the monomer. The findings led to successful labeling of human lymphocyte subpopulations.
Rembaum, A.↗
Development of biological and nonbiological explanations for the Viking label release data
The plausibility that hydrogen peroxide, widely distributed within the Mars surface material, was responsible for the evocative response obtained by the Viking Labeled Release (LR) experiment on Mars was investigated. Although a mixture of gamma Fe2O3 and silica sand stimulated the LR nutrient reaction with hydrogen peroxide and reduced the rate of hydrogen decomposition under various storage conditions, the Mars analog soil prepared by the Viking Inorganic Analysis Team to match the Mars analytical data does not cause such effects. Nor is adequate resistance to UV irradiation shown. On the basis of the results and consideration presented while the hydrogen peroxide theory remains the most, if not only, attractive chemical explanation of the LR data, it remains unconvincing on critical points. Until problems concerning the formation and stabilization of hydrogen peroxide on the surface of Mars can be overcome, adhere to the scientific evidence requires serious consideration of the biological theory.
Source record↗
Evaluation of Bayesian Sequential Proportion Estimation Using Analyst Labels
The author has identified the following significant results. A total of ten Large Area Crop Inventory Experiment Phase 3 blind sites and analyst-interpreter labels were used in a study to compare proportional estimates obtained by the Bayes sequential procedure with estimates obtained from simple random sampling and from Procedure 1. The analyst error rate using the Bayes technique was shown to be no greater than that for the simple random sampling. Also, the segment proportion estimates produced using this technique had smaller bias and mean squared errors than the estimates produced using either simple random sampling or Procedure 1.
Lennington, R. K.↗
Completion of the Viking Labeled Release experiment on Mars
The final Labeled Release (LR) cycle on each Viking lander tested a surface sample that had been stored for several months at approximately 10 C prior to the onset of the active sequence. At each lander site, activity was strongly diminished. This thermal sensitivity of the active agent on the surface of Mars is consistent with a biological explanation of the LR experiment. At the end of one of these cycles, the incubation mixture was heated to 50 C to release any radioactive gas trapped in the sample matrix. The results suggest that more than one carbon substrate is involved in the LR reaction on Mars. The thermal data from the stored samples, coupled with data from previous cycles, have formed the basis for evaluation of the thermal decomposition of the Mars active agent. The slope of the resulting Arrhenius plot has been used to test the fit of other flight data and to calculate the activation energy for thermal decomposition of the Mars agent. The results and their interpretation still leave unresolved the question of whether the Mars LR data were generated by biological or chemical activity.
Levin, G. V.↗
Microcomputer Multiplexes Alphanumeric Labels on CRT's
External, low-power alphanumeric label generator eliminates costly video circuitry. Microprocessor-based system for multiplexing alphanumeric and analog data stores both program and data. Uses inexpensive circuits, consumes minimal current, is programmable by user, adapts to many CRT monitors. System generates 5-by-7 dot-matrix characters. System speed is adaquate for medical monitoring purposes.
Cooper, T.↗
Smectites versus palagonites in Mars soil: Evidence from simulations of Viking biology labeled release experiments
The results of an experimental comparison between palagonites and a smectite (montmorillonite) in the simulation of the Viking Biology Labeled Release (LR) experiment and conclusions regarding their suitability as MarSAMs are reproved. It was found that palagonites do not cause formate decomposition and C-14 release in their natural form or after acidification and thus cannot be a completely satisfactory analog to the Mars soil studied by Viking.
Banin, A.↗
Edge Labels for Multilayer Circuit Boards
Quick visual inspection identifies out-of-place layers. Small copper pads or other labels on layers present regular pattern if multilayer circuit board properly assembled and irregular pattern if one or more layers in wrong place. New method faster, cheaper, and more reliable than earlier methods.
Rossi, P. J.↗
Metabolism of Nonessential N15-Labeled Amino Acids and the Measurement of Human Whole-Body Protein Synthesis Rates
Eight N-15 labeled nonessential amino acids plus (15)NH4Cl were administered over a 10 h period to four healthy adult males using a primed-constant dosage regimen. The amount of N-15 excreted in the urine and the urinary ammonia, hippuric acid, and plasma alanine N-15 enrichments were measured. There was a high degree of consistency across subjects in the ordering of the nine compounds based on the fraction of N-15 excreted (Kendall coefficient of concordance W = 0.83, P is less than 0.01). Protein synthesis rates were calculated from the urinary ammonia plateau enrichment and the cumulative excretion of N-15. Glycine was one of the few amino acids that gave similar values by both methods.
Stein, T. P.↗
Metabolism of nonessential N-15-labeled amino acids and the measurement of human whole-body protein synthesis rates
Eight N-15-labeled nonessential amino acids plus (N-15)H4Cl were administered over a 10-h period to four healthy adult males using a primed-constant dosage regimen. The amount of N-15 excreted in the urine and the urinary ammonia, hippuric acid, and plasma alanine N-15 enrichments were measured. There was a high degree of consistency across subjects in the ordering of the nine compounds based on the fraction of N-15 excreted.
Stein, T. P.↗
Parallel algorithms for geometric connected component labeling on a hypercube multiprocessor
Different algorithms for the geometric connected component labeling (GCCL) problem are defined each of which involves d stages of message passing, for a d-dimensional hypercube. The major idea is that in each stage a hypercube multiprocessor increases its knowledge of domain. The algorithms under consideration include the QUAD algorithm for small number of processors and the Overlap Quad algorithm for large number of processors, subject to the locality of the connected sets. These algorithms differ in their run time, memory requirements, and message complexity. They were implemented on an Intel iPSC2/D4/MX hypercube.
Belkhale, K. P.↗