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At least 91 records · Page 5

A free association semantic task for fNIRS-based perinatal depression assessment

Perinatal depression (PD) is a highly prevalent psychological disorder that has a detrimental effect on infant and maternal physical and mental health, but effective and objective assessment of PD is still insufficient. In recent years, the functional near-infrared spectroscopy (fNIRS) has been acknowledged as an effective non-invasive tool for clinical assessment of depression. This study proposed a free association semantic task (FAST) paradigm for fNIRS-based assessment of PD. To better address the emotion characteristics of PD, the participants are required to generate a dynamic concept chain based on positive, negative or neutral seed words, while 48-channel fNIRS recordings over frontal and bilateral temporal regions. Results from twenty-two late-pregnant women revealed that, the oxyhemoglobin (oxy-Hb) changes during the FAST with the positive and negative seed words over the frontal region were correlated with PD severity, which was different from the correlation patterns in the FAST with neutral seed word and the classical verbal fluency test (VFT). Furthermore, distinct correlation patterns were also observed in the FAST with the positive and negative seed words, manifested in fNIRS channels corresponding to the right dorsolateral prefrontal cortex (DLPFC) and right inferior frontal gyrus (IFG), respectively. Moreover, regression analyses showed that the FAST with positive and negative seed words can well explain the severity of PD. Our findings suggest the proposed FAST paradigm as a promising approach for PD assessment.

Chen, Danni

Physical Exercise Program

The topics discussed include the following: the Marshall Space Flight Center Physical Education Program and the physical fitness and health breakout session.

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NASA Plan for Increasing Access to the Results of Scientific Research

This plan is issued in response to the Executive Office of the President's February 22, 2013, Office of Science and Technology Policy (OSTP) Memorandum for the Heads of Executive Departments and Agencies, "Increasing Access to the Results of Federally Funded Scientific Research." Through this memorandum, OSTP directed all agencies with more than $100 million in annual research and development expenditures to prepare a plan for improving the public's access to the results of federally funded research. The National Aeronautics and Space Administration (NASA) invests on the order of $3 billion annually in fundamental and applied research and technology development1 across a broad range of topics, including space and Earth sciences, life and physical sciences, human health, aeronautics, and technology. Promoting the full and open sharing of data with research communities, private industry, academia, and the general public is one of NASA's longstanding core values. For example, NASA's space and suborbital mission personnel routinely process, archive, and distribute their data to researchers around the globe. This plan expands the breadth of NASA's open-access culture to include data and publications for all of the scientific research that the Agency sponsors.

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Food Acceptability, Menu Fatigue, and Aversion on ISS Missions

The acceptability of the spaceflight food system has been linked to caloric intake and associated nutritional benefits. The diets of the United States Operating Segment crewmembers during a mission are restricted to 200 processed and prepackaged standard menu items supplemented with personal preference foods. ISS crew members have noted in debriefs that they would prefer more food variety for the length of the missions and they tire of certain foods over six months. It is possible that menu fatigue leads to decreases in acceptability and increased aversion to available foods, potentially contributing to the body mass loss often experienced by ISS crew. However, the impact of repeat food consumption on acceptability within the current spaceflight food system has not yet been systematically investigated. Limited variety and crew preferences within food categories may have more severe physical and behavioral health and performance consequences as mission duration increases. Characterizing the relationship between food acceptability and mission duration will contribute to defining requirements for an acceptable food system that will support crew health and performance on long duration missions.

Douglas, Grace L.

Food Acceptability, Menu Fatigue, and Aversion During the Sirius-21 Analog Mission

Spaceflight food systems are closed systems, meaning they are restricted to the variety and quantity of food launched within resource limitations of the mission. The acceptability of the food system has been linked to caloric intake and associated nutritional benefits. ISS crew members receive substantial personal food preferences (around 25% of their total intake) but have noted in debriefs that they would prefer more food variety and preference for the length of the missions and they tire of certain foods over six months. Limits on variety and personal preference are expected to increase as missions become further from Earth. It is possible that menu fatigue leads to decreases in acceptability and increased aversion to available foods that may contribute to the body mass loss often experienced by spaceflight crews. However, the impact of repeat food consumption on acceptability has not yet been systematically investigated across potential spaceflight food systems. Limited variety and crew preferences within food categories may have more severe physical and behavioral health and performance consequences as mission duration increases. Characterizing the relationship between food acceptability and mission duration will contribute to defining requirements for an acceptable food system that will support crew health and performance on long duration missions. This study evaluated acceptability of the food system used in the SIRIUS-21 8-month mission in Moscow, Russia. To capture in situ scoring of repeat consumption experiences, we administered a weekly food acceptability questionnaire to all 5 crewmembers throughout the mission. Crewmembers scored foods they consumed at 3 meals every 6 days on a 9-point hedonic scale and provided open-ended feedback regarding food context, attributes, and the meal. The sequence was intended to capture all days in the 7-day menu cycle. The repetition was intended to target repeat food ratings that may provide insight into onset of menu fatigue where they might stop eating some foods or limit their choices to their favorites. Every 30 days crewmembers completed two additional surveys to characterize the food system, any changes to the food system, and their experience with the food system. Data collection is complete. Data are currently being assessed by descriptive statistics and visualizations of the ratings over time. The primary goal is to look for trends in the trajectories of ratings of the food items over time – both within and between individuals – to determine if there are substantial decreases in acceptability across all foods, or within specific food categories (e.g., vegetables). The number of times a particular item is scored provides some information on the frequency of consumption (preference), and the overall number of unique items can give a measure of overall variety. We will assess whether individuals were more likely to have more observations on food items that are rated higher, and whether those who rated foods higher had more or less overall variety. Since the data are composed of longitudinal subjective ratings, repeated measures techniques will be used to quantify trends over time and how these may relate to preference and variety. We will assess how these trends relate to their characterization of and experience with the SIRIUS-21 food system. We will also provide content analysis of any additional feedback collected on the open-ended questions and debrief interviews.

Grace L. Douglas

Know Before You Go: A Community-Derived Approach to Planning for and Preventing Sexual Harassment at Oceanographic Field Sites

Sexual harassment is a pervasive problem on oceanographic research vessels and while conducting fieldwork in general. A variety of factors contribute to inadequate protection against sexual harassment, such as poor training in prevention, support, and response; the remoteness of field sites; academic hierarchies that reinforce uneven power dynamics that extend to fieldwork; and multi-institutional teams with distinct policies or reporting structures that can lead to confusion in reporting and responding to incidents in the field. In compromising individuals’ physical and mental health, sexual harassment can negatively affect research expeditions. For example, harassed individuals may decide to refrain from working on complicated team-based tasks, which can be a safety issue. A broader concern is that sexual harassment deters talented people from pursing or maintaining employment in ocean science. Harassment must be treated with the same gravity as research misconduct and safety policy infringements. When planning a research expedition, science team leaders are responsible for the safety of their team and other colleagues aboard and would benefit from resources aimed at helping team leadership create a plan to ensure safety and inclusivity. To address this resource gap and support consistent safety preparedness, 18 participants in the Workshop to Promote Field Safety in Ocean Sciences, convened by the Consortium for Ocean Leadership and held May 17-18, 2022, in Washington, D.C., developed a checklist for use by scientific leaders and others to assist in planning for participant safety and to prevent harassment the field. The checklist specifies the timing of, and who is responsible for, specific actions that should be taken to improve safety while conducting fieldwork, whether on a research vessel or on land. It also provides additional resources and suggestions for leaders on how to amend the checklist to address their specific fieldwork situations.

Oceanography

Radiation health research, 1986 - 1990

A collection of 225 abstracts of radiation research sponsored by NASA during the period 1986 through 1990 is reported. Each abstract was categorized within one of four discipline areas: physics, biology, risk assessment, and microgravity. Topic areas within each discipline were assigned as follows: Physics - atomic physics, nuclear science, space radiation, radiation transport and shielding, and instrumentation; Biology - molecular biology, cellular radiation biology, tissue, organs and organisms, radioprotectants, and plants; Risk assessment - radiation health and epidemiology, space flight radiation health physics, inter- and intraspecies extrapolation, and radiation limits and standards; and Microgravity. When applicable subareas were assigned for selected topic areas. Keywords and author indices are provided.

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An Assessment of Environmental Health Needs

Environmental health fundamentally addresses the physical, chemical, and biological risks external to the human body that can impact the health of a person by assessing and controlling these risks in order to generate and maintain a health-supportive environment. In manned spacecraft, environmental health risks are mitigated by a multi-disciplinary effort, employing several measures including active and passive controls, by establishing environmental standards (SMACs, SWEGs, microbial and acoustics limits), and through environmental monitoring. Human Health and Performance (HHP) scientists and Environmental Control and Life Support (ECLS) engineers consider environmental monitoring a vital component to an environmental health management strategy for maintaining a healthy crew and achieving mission success. ECLS engineers use environmental monitoring data to monitor and confirm the health of ECLS systems, whereas HHP scientists use the data to manage the health of the human system. Because risks can vary between missions and change over time, environmental monitoring is critical. Crew health risks associated with the environment were reviewed by agency experts with the goal of determining risk-based environmental monitoring needs for future NASA manned missions. Once determined, gaps in environmental health knowledge and technology, required to address those risks, were identified for various types of exploration missions. This agency-wide assessment of environmental health needs will help guide the activities/hardware development efforts to close those gaps and advance the knowledge required to meet NASA manned space exploration objectives. Details of the roadmap development and findings are presented in this paper.

Macatangay, Ariel V.

An Assessment of Environmental Health Needs for Manned Spacecraft

Environmental health fundamentally addresses the physical, chemical, and biological risks external to the human body that can impact the health of a person by assessing and controlling these risks in order to generate and maintain a health‐supportive environment. Environmental monitoring coupled with other measures including active and passive controls and the implementation of environmental standards (SMACs, SWEGs, microbial and acoustics limits) are used to ensure environmental health in manned spacecraft. NASA scientists and engineers consider environmental monitoring a vital component to an environmental health management strategy for maintaining a healthy crew and achieving mission success. Environmental monitoring data confirms the health of ECLS systems, in addition to contributing to the management of the health of human systems. Crew health risks associated with the environment were reviewed by agency experts with the goal of determining risk-based environmental monitoring needs for future NASA manned missions. Once determined, gaps in knowledge and technology, required to address those risks, were identified for various types of Exploration missions. This agency‐wide assessment of environmental health needs will help guide the activities/hardware development efforts to close those gaps and advance the knowledge required to meet NASA manned space exploration objectives. Details of this assessment and findings are presented in this paper.

Macatangay, Ariel V.

Space radiation health research, 1991-1992

The present volume is a collection of 227 abstracts of radiation research sponsored by the NASA Space Radiation Health Program for the period 1991-1992. Each abstract has been categorized within one of three discipline areas: Physics, Biology and Risk Assessment. Topic areas within each discipline have been assigned as follows: Physics - Atomic Physics, Theory, Cosmic Ray and Astrophysics, Experimental, Environments and Environmental Models, Solar Activity and Prediction, Experiments, Radiation Transport and Shielding, Theory and Model Development, Experimental Studies, and Instrumentation. Biology - Biology, Molecular Biology, Cellular Radiation Biology, Transformation, Mutation, Lethality, Survival, DNA Damage and Repair, Tissue, Organs, and Organisms, In Vivo/In Vitro Systems, Carcinogenesis and Life Shortening, Cataractogenesis, Genetics/Developmental, Radioprotectants, Plants, and Other Effects. Risk Assessment - Risk Assessment, Radiation Health and Epidemiology, Space Flight Radiation Health Physics, Inter- and Intraspecies Extrapolation and Radiation Limits and Standards. Section I contains refereed journals; Section II contains reports/meetings. Keywords and author indices are provided. A collection of abstracts spanning the period 1986-1990 was previously issued as NASA Technical Memorandum 4270.

Jablin, M. H.

A Digital Twin Framework Utilizing Machine Learning for Robust Predictive Maintenance: Enhancing Tire Health Monitoring

We introduce a novel digital twin (DT) framework for the predictive maintenance of long-term physical systems. Using monitoring tire health as an application, we show how the DT framework can be used to enhance automotive safety and efficiency, and how the technical challenges can be overcome using a three-step approach. First, to manage the data complexity over a long operation span, we employ data reduction techniques to concisely represent physical tires using historical performance and usage data. Relying on these data, for fast real-time prediction, we train a transformer-based model offline on our concise dataset to predict future tire health over time, represented as remaining casing potential (RCP). Based on our architecture, our model quantifies both epistemic and aleatoric uncertainties, providing reliable confidence intervals around predicted RCP. Second, to incorporate real-time data, we update the predictive model in the DT framework, ensuring its accuracy throughout its lifespan with the aid of hybrid modeling and the use of the discrepancy function. Third, to assist decision-making in predictive maintenance, we implement a tire state decision algorithm, which strategically determines the optimal timing for tire replacement based on RCP forecasted by our transformer model. This approach ensures that our DT accurately predicts system health, continually refines its digital representation, and supports predictive maintenance decisions. Furthermore, our framework effectively embodies a physical system, leveraging big data and machine learning (ML) for predictive maintenance, model updates, and decision-making.

advanced computing infrastructure

Prognostics and Health Monitoring in Li-Ion Batteries and Capacitors Using Physics-Based Modeling Approach

In order to tackle and solve the prediction problem of the lifetime of Li-ion batteries, it is essential to have awareness of the current state and health of the battery pack. To be able to accurately predict the future state of any system, one must possess knowledge of its current and future operations. Using derived models of the current and future system behavior, a model-based prognostics approach can be implemented as a solution to the prediction problem. As more and more autonomous electric vehicles progressively emerge in our daily life, a very critical challenge lies in accurate prediction of remaining useful life of the systems/subsystems. Batteries, power electronics conditioning systems, and motors are integrated to form the powertrain in electric vehicles; one of the most critical systems. In the case of electric aircrafts, computing remaining flying time is critical for safety, since an aircraft that runs out of power (battery charge) while in the air will eventually lose control leading to catastropheThis presentation covers a physics-based modeling approach implemented for case studies in capacitor and battery prognostics which are an integral part of an electrical powertrain system. The general approach of model-based prognostics will be examined as a potential solution for safety critical problems related to battery state of charge and state of health.

Physics based modeling

Influences of Regional Climate Change on Air Quality Across the Continental U.S. Projected from Downscaling IPCC AR5 Simulations

Projecting climate change scenarios to local scales is important for understanding, mitigating, and adapting to the effects of climate change on society and the environment. Many of the global climate models (GCMs) that are participating in the Intergovernmental Panel on Climate Change (IPCC) Fifth Assessment Report (AR5) do not fully resolve regional-scale processes and therefore cannot capture regional-scale changes in temperatures and precipitation. We use a regional climate model (RCM) to dynamically downscale the GCM's large-scale signal to investigate the changes in regional and local extremes of temperature and precipitation that may result from a changing climate. In this paper, we show preliminary results from downscaling the NASA/GISS ModelE IPCC AR5 Representative Concentration Pathway (RCP) 6.0 scenario. We use the Weather Research and Forecasting (WRF) model as the RCM to downscale decadal time slices (1995-2005 and 2025-2035) and illustrate potential changes in regional climate for the continental U.S. that are projected by ModelE and WRF under RCP6.0. The regional climate change scenario is further processed using the Community Multiscale Air Quality modeling system to explore influences of regional climate change on air quality.

Air quality control

The role of physical examinations and education in prospective medicine

NASA's prospective medicine program, with the principal elements of physical examinations and an educational program for health awareness is described. Participation in the voluntary physical examination program is increasing. In 1976 13,621 employees were given partial or complete examination in NASA Health Units. From the 941 examinations performed at NASA Headquarters in 1976, 522 principal findings were detected. Equipment and techniques in exercise EKG, tonometry, and colonoscopy were partially responsible for this high rate. The health awareness program includes consultations with physicians, training devices and courses, health bulletins, and special screening programs. Epidemiological studies, now underway, will be used to evaluate the health awareness programs.

Jones, W. L.

An architecture for object-oriented intelligent control of power systems in space

A control system for autonomous distribution and control of electrical power during space missions is being developed. This system should free the astronauts from localizing faults and reconfiguring loads if problems with the power distribution and generation components occur. The control system uses an object-oriented simulation model of the power system and first principle knowledge to detect, identify, and isolate faults. Each power system component is represented as a separate object with knowledge of its normal behavior. The reasoning process takes place at three different levels of abstraction: the Physical Component Model (PCM) level, the Electrical Equivalent Model (EEM) level, and the Functional System Model (FSM) level, with the PCM the lowest level of abstraction and the FSM the highest. At the EEM level the power system components are reasoned about as their electrical equivalents, e.g, a resistive load is thought of as a resistor. However, at the PCM level detailed knowledge about the component's specific characteristics is taken into account. The FSM level models the system at the subsystem level, a level appropriate for reconfiguration and scheduling. The control system operates in two modes, a reactive and a proactive mode, simultaneously. In the reactive mode the control system receives measurement data from the power system and compares these values with values determined through simulation to detect the existence of a fault. The nature of the fault is then identified through a model-based reasoning process using mainly the EEM. Compound component models are constructed at the EEM level and used in the fault identification process. In the proactive mode the reasoning takes place at the PCM level. Individual components determine their future health status using a physical model and measured historical data. In case changes in the health status seem imminent the component warns the control system about its impending failure. The fault isolation process uses the FSM level for its reasoning base.

Holmquist, Sven G.

Overionized plasma in the supernova remnant Sagittarius A East anchored by XRISM observations

Sagittarius A East is a supernova remnant with a unique surrounding environment, as it is located in the immediate vicinity of the supermassive black hole at the Galactic center, Sagittarius A$^{*}$. The X-ray emission of the remnant is suspected to show features of overionized plasma, which would require peculiar evolutionary paths. We report on the first observation of Sagittarius A East with the X-Ray Imaging and Spectroscopy Mission (XRISM). Equipped with a combination of a high-resolution microcalorimeter spectrometer and a large field-of-view CCD imager, we for the first time resolved the Fe xxv K-shell lines into fine structure lines and measured the forbidden-to-resonance intensity ratio to be $1.39 \pm 0.12$, which strongly suggests the presence of overionized plasma. We obtained a reliable constraint on the ionization temperature just before the transition into the overionization state, of $\gt\! 4\:$keV. The recombination timescale was constrained to be $\lt\! 8 \times 10^{11} \:$cm$^{-3}\:$s. The small velocity dispersion of $109 \pm 6\:$km$\:$s$^{-1}$ indicates a low Fe ion temperature $\lt\! 8\:$keV and a small expansion velocity $\lt\! 200\:$km$\:$s$^{-1}$. The high initial ionization temperature and small recombination timescale suggest that either rapid cooling of the plasma via adiabatic expansion from dense circumstellar material or intense photoionization by Sagittarius A$^{*}$ in the past may have triggered the overionization.

galaxy center

Accurate universal parameterization of absorption cross sections

We present a simple universal parameterization of total reaction cross sections for any system of colliding nuclei valid for the entire energy range from a few A MeV to a few A GeV. The universal picture presented here treats the proton-nucleus collision as a special case of the nucleus-nucleus collision, where the projectile has charge and mass number one. The parameters are associated with the physics of the collision system. In general terms Coulomb interaction modifies cross sections at lower energies and the effects of Pauli blocking are important at higher energies. The agreement between the calculated and experimental data is better than all earlier published results.

NASA Discipline Radiation Health

Chemical Process Safety at TRISO-Based, Metal-Based, and Salt-Based Fuel Fabrication Facilities: Technical Assessment and Guidance Assessment

As part of efforts to prepare for potential and ongoing safety reviews for licensing of advanced non-light-water reactor fuel cycles, the U.S. Nuclear Regulatory Commission (NRC) tasked Pacific Northwest National Laboratory to prepare an assessment on the state of knowledge of potential chemical processes at fuel cycle facilities supporting the front end of these fuel cycles, and to assess the associated regulatory guidance. This report provides a technical assessment of chemical process safety considerations to support NRC licensing reviews of fabrication processes for tri-structural isotropic (TRISO) based, metallic-based, and salt-based fuels. The assessments involved collecting publicly available information on the fuel fabrication processes to (i) identify the operational process steps, characteristics and chemicals involved, (ii) identify the physical safety considerations and health safety considerations during licensing reviews of the various process steps, and (iii) collect information to support assessments of severity of accidents and potential mitigative measures to be implemented. The assessment provides a foundational basis on chemical process safety considerations for advanced fuel fabrication activities, although it is recognized that licensing reviews may necessitate design-specific considerations. The specific conditions under which chemical hazards emerge will require process-specific considerations, highlighting the importance of process-informed interpretation. The assessment also determined that exposure guidelines and limits to assess the consequences of acute exposures are limited for some chemicals, although alternative limits and supplementary information from databases or safety data sheets provide sufficient information to evaluate consequences of acute exposures. In addition, it was identified that metallic and salt fuel fabrication processes may involve beryllium, which is an exposure hazard. The regulatory framework for the licensing of advanced fuel cycle facilities, per 10 CFR Part 70 Domestic Licensing of Special Nuclear Material, is deemed robust and flexible to address the chemical safety considerations in this report. A review was conducted on various regulatory guidance and technical basis documents. This included reviewing NUREG-1520, Revision 2, Standard Review Plan for Fuel Cycle Facilities License Applications – Final Report and the process descriptions in Appendix A of NUREG/CR-6410, Nuclear Fuel Cycle Facility Accident Analysis Handbook, to address advanced fuel types. As new fuels will involve process-specific chemical uses, process-specific considerations are provided in this report. Additionally, it is noted that the U.S. Department of Energy protective action criteria database includes Temporary Emergency Exposure Limits (TEELs) for process-specific chemicals. This report provides technical information to support chemical safety assessments of new advanced fuel cycle facilities and identifies technical and safety information to support licensing reviews. No regulatory barriers were identified for the licensing of advanced fuel cycle facilities.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS