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At least 91 records · Page 5

A natural basis for efficient brain-actuated control

The prospect of noninvasive brain-actuated control of computerized screen displays or locomotive devices is of interest to many and of crucial importance to a few 'locked-in' subjects who experience near total motor paralysis while retaining sensory and mental faculties. Currently several groups are attempting to achieve brain-actuated control of screen displays using operant conditioning of particular features of the spontaneous scalp electroencephalogram (EEG) including central mu-rhythms (9-12 Hz). A new EEG decomposition technique, independent component analysis (ICA), appears to be a foundation for new research in the design of systems for detection and operant control of endogenous EEG rhythms to achieve flexible EEG-based communication. ICA separates multichannel EEG data into spatially static and temporally independent components including separate components accounting for posterior alpha rhythms and central mu activities. We demonstrate using data from a visual selective attention task that ICA-derived mu-components can show much stronger spectral reactivity to motor events than activity measures for single scalp channels. ICA decompositions of spontaneous EEG would thus appear to form a natural basis for operant conditioning to achieve efficient and multidimensional brain-actuated control in motor-limited and locked-in subjects.

NASA Discipline Space Human Factors↗

Processing electrophysiological signals for the monitoring of alertness

Mathematical techniques are described for processing EEG signals associated with varying states of alertness. Fast algorithms for implementing real-time computations of alertness estimates were developed. A realization of the phase-distortionless digital filter is presented which approaches real-time filtering and a transform for EEG signals. This transform provides information for the alertness estimates and can be performed in real time. A statistical test for stationarity in EEG signals is being developed that will provide a method for determining the duration of the EEG signals necessary for estimating the short-time power or energy spectra for nonstationary analysis of EEG signals.

Lai, D. C.↗

Automated electroencephalography system and electroencephalographic coordinates of space motion sickness, part 1

A self-contained and portable device which permits clinical electroencephalography (EEG) to be conducted in remote locations by minimally trained, nontechnical personnel was developed and tested. The unit accomplishes semiautomatic acquisition of EEG data from the patient, simultaneous transmission of eight data channels to a central hospital facility over conventional telephone equipment, and automatic printing (at the remote site) of the EEG report generated at the central location. Consequently, this system enables the delivery of high-quality EEG diagnostic services in a geographically remote site with the accuracy and speed formerly possible only in certain large medical centers. Beside obvious potential clinical applications, this system serves as an initial prototype of a unit which could provide inflight EEG during future space missions.

Frost, J. D., Jr.↗

Automated electroencephalography system and electroencephalographic correlates of space motion sickness, part 4

Comparative data for further assessments of the EEG alterations seen during Skylab are elaborated. The variability of alpha, beta, theta, and delta EEG characteristics was analyzed with quantitative computer techniques in a group of six normal individuals over a period of two months, and the EEG effects of a prolonged period of bed rest were evaluated in two subjects. The results confirm that the inflight EEG changes seen during Skylab are statistically significant, but the absolute values obtained for the various parameters do not exceed the maximal range expected in a normal population. Further, the EEG manifestations of extended bed rest do not appear similar to those of space flight.

Frost, J. D., Jr.↗

Multimodal Neuroelectric Interface Development

This project aims to improve performance of NASA missions by developing multimodal neuroelectric technologies for augmented human-system interaction. Neuroelectric technologies will add completely new modes of interaction that operate in parallel with keyboards, speech, or other manual controls, thereby increasing the bandwidth of human-system interaction. We recently demonstrated the feasibility of real-time electromyographic (EMG) pattern recognition for a direct neuroelectric human-computer interface. We recorded EMG signals from an elastic sleeve with dry electrodes, while a human subject performed a range of discrete gestures. A machine-teaming algorithm was trained to recognize the EMG patterns associated with the gestures and map them to control signals. Successful applications now include piloting two Class 4 aircraft simulations (F-15 and 757) and entering data with a "virtual" numeric keyboard. Current research focuses on on-line adaptation of EMG sensing and processing and recognition of continuous gestures. We are also extending this on-line pattern recognition methodology to electroencephalographic (EEG) signals. This will allow us to bypass muscle activity and draw control signals directly from the human brain. Our system can reliably detect P-rhythm (a periodic EEG signal from motor cortex in the 10 Hz range) with a lightweight headset containing saline-soaked sponge electrodes. The data show that EEG p-rhythm can be modulated by real and imaginary motions. Current research focuses on using biofeedback to train of human subjects to modulate EEG rhythms on demand, and to examine interactions of EEG-based control with EMG-based and manual control. Viewgraphs on these neuroelectric technologies are also included.

Trejo, Leonard J.↗

Awareness during drowsiness: dynamics and electrophysiological correlates

During drowsy periods, performance on tasks requiring continuous attention becomes intermittent. Previously, we have reported that during drowsy periods of intermittent performance, 7 of 10 participants performing an auditory detection task exhibited episodes of non-responding lasting about 18 s (Makeig & Jung, 1996). Further, the time patterns of these episodes were repeated precisely in subsequent sessions. The 18-s cycles were accompanied by counterbalanced power changes within two frequency bands in the vertex EEG (near 4 Hz and circa 40 Hz). In the present experiment, performance patterns and concurrent EEG spectra were examined in four participants performing a continuous visuomotor compensatory tracking task in 15-20 minute bouts during a 42-hour sleep deprivation study. During periods of good performance, participants made compensatory trackball movements about twice per second, attempting to keep a target disk near a central ring. Autocorrelations of time series representing the distance of the target disk from the ring centre showed that during periods of poor performance marked near-18-s cycles in performance again appeared. There were phases of poor or absent performance accompanied by an increase in EEG power that was largest at 3-4 Hz. These studies show that in drowsy humans, opening and closing of the gates of behavioural awareness is marked not by the appearance of (12-14 Hz) sleep spindles, but by prominent EEG amplitude changes in the low theta band. Further, both EEG and behavioural changes during drowsiness often exhibit stereotyped 18-s cycles.

Controlled Clinical Trial↗

The electrocortical correlates of fluctuating states of attention during vigilance tasks

This study investigated the electrocortical correlates of attention. Sixteen subjects (seven females, nine males) engaged in a forty-minute target detection vigilance task. Task-irrelevant probe tones were presented every 2-4 seconds. While performing the vigilance task, the subjects were asked to press a button if they were daydreaming (i.e. having a task unrelated thought or TUT). Continuous electroencephalograms (EEG's) and event-related potentials (ERP's) were recorded from the subjects during the entire task. The continuous EEG data were analyzed for differences in absolute power throughout the task as well as before and after the subjects indicated that they were daydreaming (TUT response). ERP's elicited by task-irrelevant probe tones were analyzed in the same manner. The results indicated performance decrements as reflected by increased RT to correct detections, and decreased number of hits. Further, as the task progressed, the number of reports of daydreaming increased. The analysis of the EEG data indicated a significant difference in the absolute power of the different frequency bands across periods. The greatest difference was observed at the posterior parietal electrode sites. In addition, when the EEG data was converted into band ratios (beta/alpha and beta/alpha+theta), the pre-TUT conditions were found to be significantly different than the post-TUT conditions in the posterior sites. The ERP components (N1, N2, and P2) were not significantly different before and after a TUT response or across periods. However, the ERP's across periods exhibited amplitudes that were similar to those found in previous studies of vigilance and ERP's.

Cunningham, Stephen G.↗

Neural network classification of clinical neurophysiological data for acute care monitoring

The purpose of neurophysiological monitoring of the 'acute care' patient is to allow the accurate recognition of changing or deteriorating neurological function as close to the moment of occurrence as possible, thus permitting immediate intervention. Results confirm that: (1) neural networks are able to accurately identify electroencephalogram (EEG) patterns and evoked potential (EP) wave components, and measuring EP waveform latencies and amplitudes; (2) neural networks are able to accurately detect EP and EEG recordings that have been contaminated by noise; (3) the best performance was obtained consistently with the back propagation network for EP and the HONN for EEG's; (4) neural network performed consistently better than other methods evaluated; and (5) neural network EEG and EP analyses are readily performed on multichannel data.

Sgro, Joseph↗

Biocybernetic Control of Vigilance Task Parameters

The major focus of the present proposal was to examine psychophysiological variables that are related to hazardous states of awareness induced by monitoring automated systems. With the increased use of automation in today's work environment, people's roles in the work place are being redefined from that of active participant to one of passive monitor. Although the introduction of automated systems has a number of benefits, there are also a number of disadvantages regarding the worker performance. Byrne and Parasuraman (1996) have argued for the use of psychophysiological measures in both the development and the implementation of adaptive automation. While both performance based and model based adaptive automation have been studied, the use of psychophysiological measures, especially EEG, offers the advantage of real time evaluation of the state of the subject. Previous investigations of the closed-loop adaptive automation system in our laboratory, supported by NASA, have employed a compensatory tracking task which involved the use of a joystick to maintain the position of a cursor in the middle of a video screen. This research demonstrated that, in an adaptive automation, closed-loop environment, subjects perform a tracking task better under a negative, compared to a positive, feedback condition. While tracking is comparable to some aspects of flying an airplane, it does not simulate the environment found in the cockpit of modern commercial airplanes. Since a large part of the flying responsibilities in commercial airplanes is automated, the primary responsibility of pilots is to monitor the automation and to respond when the automation fails. Because failures are relatively rare, pilots often suffer from hazardous states of awareness induced by long term vigilance of the automated system. Consequently, the aim of the current study was to investigate the ability of the closed-loop, adaptive automation system in a vigilance paradigm. It is also important to note that tracking involves a continuous, though low level, motor response. Since it is not clear how such activity might affect performance of the adaptive automation system, it was thought to be important to evaluate how the system functioned when there was minimal motor output by the subjects. The current study used the closed-loop system, developed at NASA-Langley Research Center, to control the state of awareness of subjects while they performed a vigilance task. Several experiments were conducted to examine the use of EEG feedback to control a target dimension used in the task. Changes in a subject's arousal, as defined by specific EEG indexes, produced stimulus changes known to affect task performance. In addition, different electrode sites, compared to previous research, were sampled to determine the optimum configuration with regard to the following criteria: (1) task performance and (2) EEG index.

Freeman, Frederick G.↗

Deblurring

In most instances, traditional EEG methodology provides insufficient spatial detail to identify relationships between brain electrical events and structures and functions visualized by magnetic resonance imaging or positron emission tomography. This article describes a method called Deblurring for increasing the spatial detail of the EEG and for fusing neurophysiologic and neuroanatomic data. Deblurring estimates potentials near the outer convexity of the cortex using a realistic finite element model of the structure of a subject's head determined from their magnetic resonance images. Deblurring is not a source localization technique and thus makes no assumptions about the number or type of generator sources. The validity of Deblurring has been initially tested by comparing deblurred data with potentials measured with subdural grid recordings. Results suggest that deblurred topographic maps, registered with a subject's magnetic resonance imaging and rendered in three dimensions, provide better spatial detail than has heretofore been obtained with scalp EEG recordings. Example results are presented from research studies of somatosensory stimulation, movement, language, attention and working memory. Deblurred ictal EEG data are also presented, indicating that this technique may have future clinical application as an aid to seizure localization and surgical planning.

Non-NASA Center↗

Measures and Models for Estimating and Predicting Cognitive Fatigue

We analyzed EEG and ERPs in a fatiguing mental task and created statistical models for single subjects. Seventeen subjects (4 F, 18-38 y) viewed 4-digit problems (e.g., 3+5-2+7=15) on a computer, solved the problems, and pressed keys to respond (intertrial interval = 1 s). Subjects performed until either they felt exhausted or three hours had elapsed. Re- and post-task measures of mood (Activation Deactivation Adjective Checklist, Visual Analogue Mood Scale) confirmed that fatigue increased and energy decreased over time. We tested response times (RT); amplitudes of ERP components N1, P2, P300, readiness potentials; and amplitudes of frontal theta and parietal alpha rhythms for change as a function of time. For subjects who completed 3 h (n=9) we analyzed 12 15-min blocks. For subjects who completed at least 1.5 h (n=17), we analyzed the first-, middle-, and last 100 error-free trials. Mean RT rose from 6.7 s to 8.5 s over time. We found no changes in the amplitudes of ERP components. In both analyses, amplitudes of frontal theta and parietal alpha rose by 30% or more over time. We used 30-channel EEG frequency spectra to model the effects of time in single subjects using a kernel partial least squares classifier. We classified 3.5s EEG segments as being from the first 100 or the last 100 trials, using random sub-samples of each class. Test set accuracies ranged from 63.9% to 99.6% correct. Only 2 of 17 subjects had mean accuracies lower than 80%. The results suggest that EEG accurately classifies periods of cognitive fatigue in 90% of subjects.

Trejo, Leonard J.↗

Multichannel Brain-Signal-Amplifying and Digitizing System

An apparatus has been developed for use in acquiring multichannel electroencephalographic (EEG) data from a human subject. EEG apparatuses with many channels in use heretofore have been too heavy and bulky to be worn, and have been limited in dynamic range to no more than 18 bits. The present apparatus is small and light enough to be worn by the subject. It is capable of amplifying EEG signals and digitizing them to 22 bits in as many as 150 channels. The apparatus is controlled by software and is plugged into the USB port of a personal computer. This apparatus makes it possible, for the first time, to obtain high-resolution functional EEG images of a thinking brain in a real-life, ambulatory setting outside a research laboratory or hospital.

Gevins, Alan↗

Some sequential, distribution-free pattern classification procedures with applications

Some sequential, distribution-free pattern classification techniques are presented. The decision problem to which the proposed classification methods are applied is that of discriminating between two kinds of electroencephalogram responses recorded from a human subject: spontaneous EEG and EEG driven by a stroboscopic light stimulus at the alpha frequency. The classification procedures proposed make use of the theory of order statistics. Estimates of the probabilities of misclassification are given. The procedures were tested on Gaussian samples and the EEG responses.

Poage, J. L.↗

Electroencephalographic monitoring of complex mental tasks

Outlined here is the development of neurophysiological procedures to monitor operators during the performance of cognitive tasks. Our approach included the use of electroencepalographic (EEG) and rheoencephalographic (REG) techniques to determine changes in cortical function associated with cognition in the operator's state. A two channel tetrapolar REG, a single channel forearm impedance plethysmograph, a Lead I electrocardiogram (ECG) and a 21 channel EEG were used to measure subject responses to various visual-motor cognitive tasks. Testing, analytical, and display procedures for EEG and REG monitoring were developed that extend the state of the art and provide a valuable tool for the study of cerebral circulatory and neural activity during cognition.

Guisado, Raul↗

Functional relationships among monitoring performance: Subjective report of thought process and compromising states of awareness

A biocybernetic system for use in adaptive automation was evaluated using EEG indices based on the beta, alpha, and theta bandwidths. Subjects performed a compensatory tracking task while their EEG was recorded and one of three engagement indices was derived: beta/(alpha + theta), beta/alpha, or 1/alpha. The task was switched between manual and automatic modes as a function of the subjects' level of engagement and whether they were under a positive or negative feedback condition. It was hypothesized that negative feedback would produce more switches between manual and automatic modes, and that the beta/(alpha + theta) index would produce the strongest effect. The results confirmed these hypotheses. There were no systematic changes in these effects over three 16-minute trials. Tracking performance was found to be better under negative feedback. An analysis of the different EEG bands under positive and negative feedback in manual and automatic modes found more beta power in the positive feedback/manual condition and less in the positive feedback/automatic condition. The opposite effect was observed for alpha and theta power. The implications of biocybernetic systems for adaptive automation are discussed.

Freeman, Frederick↗

NASA Graduate Student Researchers Program (GSRP)

The primary area of research that Dr. Prinzel conducted was concerned with the effects of automation on the ability to perform various tasks which simulated those performed in an airplane cockpit. While automation is generally considered to be a positive addition to the cockpit, it also has some negative effects. The primary negative effect is related to the decrease in the number of tasks the pilot needs to perform. Having less to do can actually result in a decreased ability to be aware of and react to ongoing events, some of which may be critical to flight operations. The research was concerned with the ability of adaptive automation using psychophysiological measures, specifically brain waves (i.e. EEG), to control the degree to which tasks are automated as a function of the subject's level of alertness. Dr. Prinzel conducted and participated in the running of a number of experiments that examined adaptive automation in conjunction with the MultiAttribute Task Battery. Since there has been very little research conducted in this area, experiments needed to be conducted which established basic parameters for future research. The experiments that Dr. Prinzel was involved with examined the optimum number and location of electrode sites for recording EEG, the types of tasks which could readily be automated, the number of tasks which could be controlled by the adaptive automation system, and various EEG recording parameters which affect system functioning. A secondary area in which Dr. Prinzel conducted research concerned performance on vigiliance tasks. This research, while not initially directly related to adaptive automation, does have implication for such systems. Vigilance requires long term monitoring which often leads to the kind of negative effects seen when automation is introduced into a work environment. A third area of research in which Dr. Prinzel conducted research was concerned with gender differences in cognitive functioning and how that related to strategies for performing various tasks.

Freeman, Frederick G.↗

External Validity Considerations of a Biocybernetic System for Adaptive Automation

The report discusses the results of a research project aimed at generating a software application library termed the DAQ EEG Processor (or DEP) that collects and processes raw electroencephalographic data. The purpose of this system is to reduce raw EEG data in real time into information that is useful to researchers, such as power bands and indices of engagement. DEP improves upon existing EEG processing systems in that it can be seamlessly integrated into many software development environments to provide realtime data. DEP takes advantage of Microsoft Corporation's Component Object Model Technology (COM), which, in short, allows language independent, inter-application communication and transfer of data. According to the COM specification, COM objects can be written in different languages, run in different process spaces and on different platforms. As long as the objects adhere to the specification, they can communicate.

Scerbo, Mark W.↗

Psychophysiological Control of Acognitive Task Using Adaptive Automation

The major focus of the present proposal was to examine psychophysiological variables related to hazardous states of awareness induced by monitoring automated systems. With the increased use of automation in today's work environment, people's roles in the work place are being redefined from that of active participant to one of passive monitor. Although the introduction of automated systems has a number of benefits, there are also a number of disadvantages regarding worker performance. Byrne and Parasuraman have argued for the use of psychophysiological measures in the development and the implementation of adaptive automation. While both performance based and model based adaptive automation have been studied, the use of psychophysiological measures, especially EEG, offers the advantage of real time evaluation of the state of the subject. The current study used the closed-loop system, developed at NASA-Langley Research Center, to control the state of awareness of subjects while they performed a cognitive vigilance task. Previous research in our laboratory, supported by NASA, has demonstrated that, in an adaptive automation, closed-loop environment, subjects perform a tracking task better under a negative than a positive, feedback condition. In addition, this condition produces less subjective workload and larger P300 event related potentials to auditory stimuli presented in a concurrent oddball task. We have also recently shown that the closed-loop system used to control the level of automation in a tracking task can also be used to control the event rate of stimuli in a vigilance monitoring task. By changing the event rate based on the subject's index of arousal, we have been able to produce improved monitoring, relative to various control groups. We have demonstrated in our initial closed-loop experiments with the the vigilance paradigm that using a negative feedback contingency (i.e. increasing event rates when the EEG index is low and decreasing event rates when the EEG index is high) results in a marked decrease of the vigilance decrement over a 40 minute session. This effect is in direct contrast to performance of a positive feedback group, as well as a number of other control groups which demonstrated the typical vigilance decrement. Interestingly, however, the negative feedback group performed at virtually the same level as a yoked control group. The yoked control group received the same order of changes in event rate that were generated by the negative feedback subjects using the closed-loop system. Thus it would appear to be possible to optimize vigilance performance by controlling the stimuli which subjects are asked to process.

Freeman, Frederick↗