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All sourcesNASA NTRSDOE OSTI
DOE OSTI2024

Abstract for CRADA between National Energy Technology Laboratory and Carbon To Stone, Inc.

The National Energy Technology Laboratory (NETL) and Carbon To Stone (CTS), Inc. (Participant) will collaborate on a techno-economic assessment (TEA) and life cycle assessment (LCA) of CTS’s carbon dioxide removal (CDR) technology under an awarded project from the Department of Energy’s Direct Air Capture Pre-Commercialization Technology Prize. CTS has developed a technological platform that captures carbon dioxide (CO2) from air and mineralizes it into durable carbonates using alkaline industrial residues such as steel slag and mine tailings. In addition, CTS’s technology uses electrochemistry to recover value-added energy critical metals (ECMs) from these residues. NETL has expertise in CDR TEA and LCA development. The collaboration between CTS and NETL aims to quantify the performance, cost and lifecycle impacts of CTS’s technology and produce LCA and TEA models that can accelerate development and deployment of this technology.

54 ENVIRONMENTAL SCIENCES↗
NASA NTRS1975

Improved TWTs for electronic countermeasure application

Some efforts in the development of a multistage depressed collector (MSDC) are reviewed. The MSDC is to operate in an electronic countermeasure system (ECM) with minimum overall efficiency in the range 35 to 50%. The effects of interception, harmonic output, and skin effect losses on the design of high-efficiency tubes with a MSDC are briefly discussed. Future experimental work will attempt to put a multistage depressed collector on a 400-watt CW 4.8 to 9.6-GHz helix TWT. By using a unique valve assembly, different collector configurations can be tested while maintaining the circuit under vacuum. The work will determine the sensitivity of overall tube efficiency to the number of collector, length of the collector, aperture size, and plate angle.

Laycock, D. E.↗
NASA NTRS1976

Design and performance evaluation of small, two- and four-stage depressed collectors for a 4.8 to 9.6 GHz high-performance traveling wave tube

A program to improve the efficiency of traveling wave tubes (TWT's) for use in electronic countermeasure (ECM) systems by applying multistage depressed collector (MDC) and spent beam refocusing techniques is studied. Three dimensional electron trajectories are computed through-out the slow wave structure of the TWT, the spent beam refocuser, and the depressed collector. Both TWT and MDC performances are analytically evaluated.

Ramins, P.↗
NASA NTRS1980

Improved traveling wave tubes

Techniques, pioneered by NASA, which will allow substantial improvements in traveling wave tube (TWT) amplifier efficiency, are described. It is shown that using design techniques developed at the Lewis Research Center, it is possible to approximately double the efficiency of the critical amplifier TWT. Attention is given to a quick method of computing the expected improvement to an ECM TWT. The benefits of such improvements such as less input power, a smaller and lighter power supply, and easier cooling are surveyed, and it noted that it is now possible to build efficient TWT's which rather than operating at saturation, can be very linear amplifiers. Finally, a new approach to power supplies is also covered.

Buck, E.↗
NASA NTRS1981

A broadband RF continuously variable time delay device

A method for implementation of continuously variable time delay of broadband RF signals is described. The method uses Bragg Cell and optical heterodyne technology. The signal to be delayed is applied to the Bragg Cell acoustic transducer, and the delay time is the acoustic transit time from this transducer to the incident light beam. By translating the light beam, the delay is varied. Expressions describing the Bragg Cell diffraction, lens Fourier transformation, and the optical heterodyne processes are developed. Specifications for the variable delay including bandwidth, range of delay, and insertion loss are provided. Applications include radar signal processing, spread spectrum intercept, radar ECM, and adaptive array antenna processing.

Freyre, F. W.↗
NASA NTRS1983

Specification for a Program for an Interative Aeroelastic Solution (PIAS)

An engineering and software specification which was written for a computer program to calculate aeroelastic structural loads including the effects of nonlinear aerodynamics is presented. The procedure used in the program for an iterative aeroelastic solution (PIAS) is to alternately execute two computer codes: one to calculate aerodynamic loads for a specific wing shape, and another to calculate the deflected shape caused by this loading. A significant advantage to the design of PIAS is that the initial aerodynamic module can be replaced with others. The leading edge vortex (LEV) program is used as the aerodynamic module in PIAS. This provides the capability to calculate aeroelastic loads, including the effects of a separation induced leading edge vortex. The finite element method available in ATLAS Integrated structural analysis and design system is used to determine the deflected wing shape for the applied aerodynamics and inertia loads. The data management capabilities in ATLAS are used by the execution control monitor (ECM) of PIAS to control the solution process.

Manro, M. E.↗
NASA NTRS1987

High-angle-of-attack stability and control improvements for the EA-6B Prowler

The factors involved in high-angle-of-attack directional divergence phenomena for the EA-6B ECM aircraft have been investigated in NASA-Langley wind tunnel facilities in order to evaluate airframe modifications which would eliminate or delay such divergence to angles-of-attack farther removed from the operational flight envelope of the aircraft. The results obtained indicate that an adverse sidewash at the aft fuselage and vertical tail location is responsible for the directional stability loss, and that the sidewash is due to a vortex system generated by the fuselage-wing juncture. Modifications encompassing a wing inboard leading edge droop, a wing glove strake, and a vertical fin extension, have significantly alleviated the stability problem.

Jordan, Frank L.↗
NASA NTRS1991

Space Communications Artificial Intelligence for Link Evaluation Terminal (SCAILET)

A software application to assis end-users of the Link Evaluation Terminal (LET) for satellite communication is being developed. This software application incorporates artificial intelligence (AI) techniques and will be deployed as an interface to LET. The high burst rate (HBR) LET provides 30 GHz transmitting/20 GHz receiving, 220/110 Mbps capability for wideband communications technology experiments with the Advanced Communications Technology Satellite (ACTS). The HBR LET and ACTS are being developed at the NASA Lewis Research Center. The HBR LET can monitor and evaluate the integrity of the HBR communications uplink and downlink to the ACTS satellite. The uplink HBR transmission is performed by bursting the bit-pattern as a modulated signal to the satellite. By comparing the transmitted bit pattern with the received bit pattern, HBR LET can determine the bit error rate BER) under various atmospheric conditions. An algorithm for power augmentation is applied to enhance the system's BER performance at reduced signal strength caused by adverse conditions. Programming scripts, defined by the design engineer, set up the HBR LET terminal by programming subsystem devices through IEEE488 interfaces. However, the scripts are difficult to use, require a steep learning curve, are cryptic, and are hard to maintain. The combination of the learning curve and the complexities involved with editing the script files may discourage end-users from utilizing the full capabilities of the HBR LET system. An intelligent assistant component of SCAILET that addresses critical end-user needs in the programming of the HBR LET system as anticipated by its developers is described. A close look is taken at the various steps involved in writing ECM software for a C&P, computer and at how the intelligent assistant improves the HBR LET system and enhances the end-user's ability to perform the experiments.

Shahidi, Anoosh↗
NASA NTRS1992

Interim report on the analysis of the microwave power module

The results of a traveling wave tube multistage depressed collector (TWT-MDC) design study in support of the DARPA/DoD Microwave Power Module (MPM) Program are described. The study stressed the MDC as a key element in obtaining the required high overall efficiencies in the MPM application. The results showed that an efficient MDC, utilizing conventional design and fabrication techniques can be designed for the first generation MPM TWT, which permits a package one wavelength thick (.66 in. at 18 GHz). The overall TWT efficiency goal of 40 percent for electronic countermeasure (ECM) applications appears to be readily achievable. However, the 50 percent goal for radar applications presents a considerable challenge.

Ramins, Peter↗
NASA NTRS1995

National Center for Manufacturing Sciences: Environmentally conscious manufacturing

The purpose of this presentation is to share the results and some of the thinking of the Environmentally Conscious Manufacturing - Strategic Initiative Group (ECM-SIG) at the National Center for Manufacturing Sciences (NCMS). NCMS is a consortium of more than 185 North American Manufacturing organizations comprised of about 75 percent for profit manufacturing companies and about 25 percent nonprofit organizations that support manufacturing activities. NCMS conducts collaborative R&D programs designed to improve global competitiveness of its members and other North American manufacturers to address common issues that are important to manufacturing industries. NCMS is an industry driven organization whose agenda is established by industry with input from appropriate government agencies.

Vinton, Clare↗
NASA NTRS2000

Role of Integrin in Mechanical Loading of Osteoblasts

Mechanical forces generated by gravity, weightbearing, and muscle contraction play a key role in the genesis and maintenance of skeletal structure. The molecular mechanisms that mediate changes in osteoblast activity in response to altered patterns of skeletal loading are not known, and a better understanding of these processes may be essential for developing effective treatment strategies to prevent disuse osteoporosis. We have elucidated specific integrin/ECM (extracellular matrix) interactions that are required for osteoblast differentiation and survival and have developed a useful loading system to further explore the molecular basis of mechano-sensitivity of osteoblasts. The long term goal of our collaborative research is to understand how the ECM and cell adhesion proteins and integrins interaction to mediate the response of osteoblasts and their progenitors to mechanical loading. We suggest that integrin/ECM interactions are crucial for basic cellular processes, including differentiation and survival, as well as to participate in detecting and mediating cellular responses to mechanical stimuli.

Globus, Ruth↗
NASA NTRS2003

Hypergravity Stimulates the Extracellular Matrix/Integrin-Signaling Axis and Proliferation in Primary Osteoblasts

We set out to determine the molecular mechanisms involved in the proliferative response of primary rat osteoblasts to mechanical stimulation using cell culture centrifugation as a model for hypergravity. We hypothesized that this proliferative response is mediated by specific integrin/Extracellular Matrix (ECM) interactions. To investigate this question we developed a cell culture centrifuge and an automated system that performs cell fixation during hypergravity loading. We generated expression vectors for various focal adhesion and cytoskeletal proteins fused to GFP or dsRed and visualized these structures in transfected (or infected) osteoblasts. The actin cytoskeleton was also visualized using rhodamine-phalloidin staining and Focal Adhesion Kinase (FAK) levels were assessed biochemically. We observed that a 24 hour exposure to 50-g stimulated proliferation compared to the 1-g control when cells were plated on fibronectin, collagen Type I , and collagen Type IV, but not on uncoated tissue culture plastic surfaces. This proliferative response was greatest for osteoblasts grown on fibronectin (2-fold increase over 1-g control) and collagen Type I (1.4 fold increase over 1-g control), suggesting that specific matrices and integrins are involved in the signaling pathways required for proliferation. Exposing osteoblasts grown on different matrices to 10-g or 25-g showed that effects on proliferation depended on both matrix type and loading level. We found that osteoblasts exposed to a short pulse of hypergravity during adhesion spread further and had more GFP-FAK containing focal adhesions compared to their 1-g controls. While overall levels of FAK did not change, more FAK was in the active (phosphorylated) form under hypergravity than in the 1-g controls. Cytoskeletal F-actin organization into filaments was also more prominent after brief exposures to hypergravity during the first five minutes of adhesion. These results suggest that specific integrins sense hypergravity and activate distinct matrix-dependent FAK signaling pathways that can enhance proliferation. Our results also imply that brief exposures to hypergravity accelerate cell adhesion and spreading processes via the focal adhesion-signaling axis. These results support the role of the ECM/integrin-signaling axis in osteoblast response to hypergravity loading.

Parra, M.↗
NASA NTRS2003

Hypergravity Stimulates Osteoblast Proliferation Via Matrix-Integrin-Signaling Pathways

Extensive characterizations of the physiologic consequences of microgravity and gravity indicate that lack of weight-bearing may cause tissue atrophy through cellular and subcellular level mechanisms. We hypothesize that gravity is needed for the efficient transduction of cell growth and survival signals from the extra-cellular matrix (ECM) in mechanosensitive tissues. Recent work from our laboratory and from others shows that an increase of gravity increases bone cell growth and survival. We found that 50-g hypergravity stimulation increased osteoblast proliferation for cells grown on Collagen Type I and Fibronectin, but not on Laminin or uncoated plastic. This may be a tissue-specific response, because 50-g hypergravity stimulation caused no increase in proliferation for primary rat fibroblasts. These results combined with RT-PCR for all possible integrins indicate that beta1 integrin subunit may be involved. The osteoblast proliferation response on Collagen Type I was greater at 25-g than at 10-g or 50-g; 24-h duration of hypergravity was necessary to see an increase in proliferation. Survival was enhanced during hypergravity stimulation by the presence of matrix. Flow cytometry analysis indicated that cell cycle may be altered; BrdU incorporation in proliferating cells showed an increase in the number of actively dividing cells from about 60% at 1-g to over 90% at 25-g. To further investigate the molecular components involved, we applied fluorescence labeling of cytoskeletal and signaling molecules to cells after 2 to 30 minutes of hypergravity stimulation. While structural components did not appear to be altered, phosphorylation increased, indicating that signaling pathways may be activated. These data indicate that gravity mechanostimulation of osteoblast proliferation involves specific matrix-integrin signaling pathways which are sensitive to duration and g-level.

Vercoutere, W.↗
NASA NTRS2004

Surface Figure Measurement at 20K: Silicon Carbide and Cesic Mirrors

This report presents the facility, methods, and results of testing cryogenically-cooled spherical mirrors, using standard phase-shifting interferometry, at the Goddard Space Flight Center (GSFC). Two mirrors were supplied to GSFC by the European Space Technology Center, so that GSFC could render a second, independent cryo-measurement of their surface figures at 20K. These mirrors, produced by Galileo Avionica and its partners, demonstrate the technology of silicon carbide and SiC-composite lightweighted mirrors, designed for high accuracy (10 nm rms surface figure error) at both room temperature and 20K. The two mirrors provided for testing at GSFC include one made of sintered silicon carbide (mirror blank by Bettini), and a second made of the C/Si/SiC composite known as Cesic (supplied by ECM). Both mirrors are f/2 spheres with 150 mm clear aperture, and with integral mounts. At GSFC, the mirrors will be measured first at at room temperature, making use of standard techniques, with a predicted uncertainty of 2 nm. Then each mirror will be tested in the cryostat, down to 20K: first freely supported and, second, mounted to a Cesic plate that models a Cesic optical bench. The uncertainty of the resultant surface figure error is predicted to be about 5 nm rms. Details of the uncertainty budget are discussed in a related poster. GSFC's techniques and results can be usefully compared to the measurements performed on the same two mirrors by and for Galileo Avionica, who used a somewhat different test configuration and alignment approach.

Blake, Peter↗
NASA NTRS1993

Embryonic lung morphogenesis in organ culture: experimental evidence for a proteoglycan function in the extracellular matrix

The lung rudiment, isolated from mid-gestation (11 day) mouse embryos, can undergo morphogenesis in organ culture. Observation of living rudiments, in culture, reveals both growth and ongoing bronchiolar branching activity. To detect proteoglycan (PG) biosynthesis, and deposition in the extracellular matrix, rudiments were metabolically labeled with radioactive sulfate, then fixed, embedded, sectioned and processed for autoradiography. The sulfated glycosaminoglycan (GAG) types, composing the carbohydrate component of the proteoglycans, were evaluated by selective GAG degradative approaches that showed chondroitin sulfate PG principally associated with the interstitial matrix, and heparan sulfate PG principally associated with the basement membrane. Experiments using the proteoglycan biosynthesis disrupter, beta-xyloside, suggest that when chondroitin sulfate PG deposition into the ECM is perturbed, branching morphogenesis is compromised.

NASA Discipline Number 93-10↗
NASA NTRS2000

Particle irradiation induces FGF2 expression in normal human lens cells

Particle Irradiation Induces FGF2 Expression in Normal Human Lens Cells. Particle radiations, including both proton and helium-ion beams, have been used to successfully treat choroidal melanoma, but with the complication of radiation-induced cataract. We have investigated a role for radiation-induced changes in the expression of basic fibroblast growth factor (FGF2) gene expression as part of the mechanism(s) underlying lens cell injury associated with cataract. Normal human lens epithelial (HLE) cells were cultured in vitro on extracellular matrix (ECM) originated from bovine corneal endothelial cells. This study reports evidence for rapid but transient induction of FGF2 transcripts, an increase of between 5- and 8-fold, within 0.5 h after exposure to particle radiation, followed by another wave of increased transcription at 2-3 h postirradiation. Immunofluorescence results confirm the enhanced levels of FGF2 protein rapidly after exposure to protons or helium ions, followed by another wave of increased activity unique to helium at 6 h postirradiation. This second wave of increased immunoreactivity was not observed in the proton-irradiated samples. Total FGF2 protein analysis after helium-ion exposures shows induced expression of three FGF2 isoforms, with an increase of up to 2-fold in the 18-kDa low-molecular-weight species. Studies of the effects of protons on individual FGF2 protein isoforms are in progress. Several mechanisms involving a role for FGF2 in radiation-induced cataract are discussed.

NASA Discipline Radiation Health↗