Nature of pleural space of dogs
Pleural space of dogs investigated by spheres injection of varying density and diameter, discussing sedimentation velocities
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Pleural space of dogs investigated by spheres injection of varying density and diameter, discussing sedimentation velocities
Eating and digestion effects on arterial pressure and mesenteric and aortic blood flows in intact unanesthetized dogs
Plasma tocopherol concentrations and vitamin E deficiency in dogs, noting pathologic changes in smooth muscle, central nervous system, skeletal muscle and retina
Body position effect on oxygen saturation of regional pulmonary venous blood and arterial- venous shunts in intact dogs
Effects of positive Gy acceleration on blood oxygen saturation and pleural pressure relations in dogs breathing air and liquid fluorocarbons in whole body water immersion respirator
Eating and digestion effects on conscious dog coronary and visceral vasoactivity
Digitalis-induced bundle branch ventricular tachycardia from electrode catheter recordings of dogs specialized conducting tissues
Cardiac arrhythmias simulated by concealed bundle of His extrasystoles in open chest intact dog hearts
Dynamic respiratory and circulatory responses to hypoxia in anesthetized dogs, recording oxygen partial pressures, heart rate, blood pressure, blood flows, respiratory rate, etc
Drug effects on LF whole body vibration response of dogs administered with phenobarbital, phenoxybenzamine and morphine
The conversion mechanism was studied in vivo in the pulmonary circulation of the intact anesthetized dog and in vitro in plasma by using L-Leu-angiotensin I, D-Leu-angiotensin I, and des-Leu-angiotensin I which had been synthesized by the solid-phase technique. The results obtained indicate that pulmonary conversion in vivo and plasma conversion in vitro occur via a dipeptidylcarboxypeptidase and that a D-amino acid at the C-terminus prevents conversion.
Investigation of the relationship between coronary flow, heart rate, left ventricular function, and myocardial oxygen consumption at increasing levels of carboxyhemoglobin in conscious dogs. The results demonstrate a linear increase in coronary flow and heart rate as the carboxyhemoglobin increases up to 20%. Myocardial oxygen consumption declined during the same period.
A nonlinear theory which considered the convective accelerations of blood and the nonlinear elastic behavior and taper angle of the vascular wall was used to study the nature of blood flow in the descending thoracic aorta of living dogs under a wide range of pressures and flows. Velocity profiles, wall friction, and discharge waves were predicted from locally measured input data about the pressure-gradient wave and arterial distention. The results indicated that a major part of the mean pressure gradient was balanced by convective accelerations; the theory, which took this factor into account, predicted the correct velocity distributions and flow waves.
Experimental data which can be used as a guideline in developing a mathematical model for lateral vibrations of whole bone are reported. The study used wet and dry dog radii mounted in a cantilever configuration. Data are also given on the mechanical, geometric, and viscoelastic properties of bones.
Immunomorphological studies on dog tissues exposed to long term gamma irradiation show that the number of cells containing antibodies increased and that the blast transformation reaction was activated. Prolonged radiation did not cause a reliable change in the synthesis of nucleic acids in spleen cells.
The effect of infusions with solutions of various ionic and osmotic composition on exercise temperature responses was studied in dogs who do not regulate their temperature by sweating. The results suggest an association between plasma Na+ and Ca++ level within the normal physiological range and the control of body temperature during exercise.
Results of studies of the Bainbridge reflex in intact conscious dogs are presented. They indicate that arterial baroreflex sensitivity is reduced progressively as atrial pressure is raised by volume loading; this observation explains how heart rate can rise markedly in the presence of an elevated arterial blood pressure.
A fastigial pressor response has been elicited in the anesthetized mongrel dog. Stimulation within the rostral portions of this nucleus results in mean arterial pressure rises up to 150 mmHg above control. A proportional tachycardia is simultaneously evoked which may rapidly attain heart rates of 190 beats/min above control levels. Peak tachycardias immediately subside and often the heart rate declines below control values during stimulation while arterial pressure remains elevated. When either the carotid sinuses were isolated by ligation or a bilateral vagotomy was performed, the fastigial tachycardia was sustained. The response could still be attained when submaximal doses of alpha-chloralose anesthesia or high levels of barbiturates (30-40 mg/kg) were given. Both portions of the response result from widespread sympathetic activation; however, buffering of the response through the baroreceptor reflexes is only demonstrated in the cardiac segment of the response.